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Search of human proteins with 46447820
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo
sapiens]
(512 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo s... 1070 0.0
gi|8923177 differentially expressed in FDCP 8 isoform 2 [Homo sa... 358 5e-99
gi|122937347 pleckstrin homology domain containing, family M, me... 178 1e-44
gi|40538728 pleckstrin homology domain containing, family M (wit... 161 2e-39
gi|224548938 hypothetical protein LOC9711 isoform 1 [Homo sapiens] 153 3e-37
gi|150456467 hypothetical protein LOC9711 isoform 2 [Homo sapiens] 153 3e-37
gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo ... 149 6e-36
gi|156151402 hypothetical protein LOC80183 [Homo sapiens] 140 3e-33
gi|239756837 PREDICTED: similar to pleckstrin homology domain co... 102 1e-21
gi|122937247 unc-13 homolog A [Homo sapiens] 42 0.001
gi|190684646 RAS guanyl releasing protein 1 isoform b [Homo sapi... 42 0.002
gi|190684644 RAS guanyl releasing protein 1 isoform a [Homo sapi... 42 0.002
gi|20149588 Ras association domain family 1 isoform A [Homo sapi... 41 0.003
gi|40806175 diacylglycerol kinase, theta [Homo sapiens] 41 0.003
gi|5453976 protein kinase C, theta [Homo sapiens] 40 0.005
gi|110611226 UNC13 (C. elegans)-like [Homo sapiens] 40 0.005
gi|213385270 RAS guanyl releasing protein 3 (calcium and DAG-reg... 40 0.007
gi|24762239 RAS guanyl releasing protein 3 (calcium and DAG-regu... 40 0.007
gi|7662334 RAS guanyl releasing protein 3 (calcium and DAG-regul... 40 0.007
gi|122937514 unc-13 homolog C [Homo sapiens] 40 0.007
gi|13384594 protein kinase C, gamma [Homo sapiens] 39 0.009
gi|215820619 zinc finger protein 646 [Homo sapiens] 39 0.011
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 39 0.011
gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo s... 39 0.011
gi|47157325 protein kinase C, delta [Homo sapiens] 39 0.015
gi|31377782 protein kinase C, delta [Homo sapiens] 39 0.015
gi|4885563 protein kinase C, epsilon [Homo sapiens] 38 0.019
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 38 0.019
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 38 0.019
gi|26051258 RAS guanyl releasing protein 4 isoform a [Homo sapiens] 37 0.033
>gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo
sapiens]
Length = 512
Score = 1070 bits (2767), Expect = 0.0
Identities = 512/512 (100%), Positives = 512/512 (100%)
Query: 1 MAILSLRAPGPWQAMQVWADRTLLTPHTGVTSQVLGVAAAVMTPLPGGHAAGRTREARWD 60
MAILSLRAPGPWQAMQVWADRTLLTPHTGVTSQVLGVAAAVMTPLPGGHAAGRTREARWD
Sbjct: 1 MAILSLRAPGPWQAMQVWADRTLLTPHTGVTSQVLGVAAAVMTPLPGGHAAGRTREARWD 60
Query: 61 AMEYDEKLARFRQAHLNPFNKQSGPRQHEQGPGEEVPDVTPEEALPELPPGEPEFRCPER 120
AMEYDEKLARFRQAHLNPFNKQSGPRQHEQGPGEEVPDVTPEEALPELPPGEPEFRCPER
Sbjct: 61 AMEYDEKLARFRQAHLNPFNKQSGPRQHEQGPGEEVPDVTPEEALPELPPGEPEFRCPER 120
Query: 121 VMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLK 180
VMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLK
Sbjct: 121 VMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLK 180
Query: 181 LQELKDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHS 240
LQELKDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHS
Sbjct: 181 LQELKDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHS 240
Query: 241 KCLNLISKPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYT 300
KCLNLISKPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYT
Sbjct: 241 KCLNLISKPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYT 300
Query: 301 GQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSY 360
GQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSY
Sbjct: 301 GQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSY 360
Query: 361 VEELVEIRKLRQDILLMKPYFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAG 420
VEELVEIRKLRQDILLMKPYFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAG
Sbjct: 361 VEELVEIRKLRQDILLMKPYFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAG 420
Query: 421 RLGCSLTEIHTLFAKHIKLDCERCQAKGFVCELCREGDVLFPFDSHTSVCADCSAVFHRD 480
RLGCSLTEIHTLFAKHIKLDCERCQAKGFVCELCREGDVLFPFDSHTSVCADCSAVFHRD
Sbjct: 421 RLGCSLTEIHTLFAKHIKLDCERCQAKGFVCELCREGDVLFPFDSHTSVCADCSAVFHRD 480
Query: 481 CYYDNSTTCPKCARLSLRKQSLFQEPGPDVEA 512
CYYDNSTTCPKCARLSLRKQSLFQEPGPDVEA
Sbjct: 481 CYYDNSTTCPKCARLSLRKQSLFQEPGPDVEA 512
>gi|8923177 differentially expressed in FDCP 8 isoform 2 [Homo
sapiens]
Length = 197
Score = 358 bits (920), Expect = 5e-99
Identities = 172/172 (100%), Positives = 172/172 (100%)
Query: 62 MEYDEKLARFRQAHLNPFNKQSGPRQHEQGPGEEVPDVTPEEALPELPPGEPEFRCPERV 121
MEYDEKLARFRQAHLNPFNKQSGPRQHEQGPGEEVPDVTPEEALPELPPGEPEFRCPERV
Sbjct: 1 MEYDEKLARFRQAHLNPFNKQSGPRQHEQGPGEEVPDVTPEEALPELPPGEPEFRCPERV 60
Query: 122 MDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKL 181
MDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKL
Sbjct: 61 MDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKL 120
Query: 182 QELKDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTG 233
QELKDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTG
Sbjct: 121 QELKDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTG 172
>gi|122937347 pleckstrin homology domain containing, family M,
member 3 [Homo sapiens]
Length = 761
Score = 178 bits (451), Expect = 1e-44
Identities = 85/234 (36%), Positives = 137/234 (58%), Gaps = 5/234 (2%)
Query: 268 ETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFE 327
E GL +Q ++CA C+ I L +A+ C+Y+G YYCS CH +D +IPAR+VHNWD
Sbjct: 504 ERGLTAQSFKCAGCQRSIGLSN--GKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTS 561
Query: 328 PRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKPYFITCREA 387
KVS+ + +L + P++ +++ N +L+ + E L + +LRQ + ++ Y +CR A
Sbjct: 562 KYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAA 621
Query: 388 MEARLLLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKLDCERCQAK 447
+ L ++ R++ ++ +YS+ DL V G+L L ++ H+ C C K
Sbjct: 622 VAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHV-YSCSLCSQK 680
Query: 448 GFVCELCREGDVLFPF-DSHTSVCADCSAVFHRDCYYDNSTTCPKCARLSLRKQ 500
GF+CE+C G++L+PF D TS C C AVFH +C + S CP+C R L+K+
Sbjct: 681 GFICEICNNGEILYPFEDISTSRCESCGAVFHSEC-KEKSVPCPRCVRRELQKK 733
>gi|40538728 pleckstrin homology domain containing, family M (with RUN
domain) member 1 [Homo sapiens]
Length = 1056
Score = 161 bits (407), Expect = 2e-39
Identities = 82/246 (33%), Positives = 137/246 (55%), Gaps = 5/246 (2%)
Query: 260 EYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPAR 319
+Y + I E GLDSQ CA C I V + C ++G YYC CH +D +VIPAR
Sbjct: 813 QYLVAIPMEKGLDSQGCFCAGCSRQIGFSFV--RPKLCAFSGLYYCDICHQDDASVIPAR 870
Query: 320 VVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKP 379
++HNWD R + R ++++L + ++P++ L+ +N L+ +VE + I + R+ + L+
Sbjct: 871 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGD 930
Query: 380 YFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKL 439
Y CR L +L R + +E+ +SV DL + G L + ++H+
Sbjct: 931 YLGLCRSGALKELSKRLNHRNYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHV-Y 989
Query: 440 DCERCQAKGFVCELCREGDVLFPFDSHTSV-CADCSAVFHRDCYYDNSTTCPKCA-RLSL 497
C+ C +GF+C++C+ D++FPF+ T+V CA+C VFH+ C CP+CA R
Sbjct: 990 HCDLCTQRGFICQICQHHDIIFPFEFDTTVRCAECKTVFHQSCQAVVKKGCPRCARRRKY 1049
Query: 498 RKQSLF 503
++Q++F
Sbjct: 1050 QEQNIF 1055
>gi|224548938 hypothetical protein LOC9711 isoform 1 [Homo sapiens]
Length = 927
Score = 153 bits (387), Expect = 3e-37
Identities = 90/239 (37%), Positives = 130/239 (54%), Gaps = 17/239 (7%)
Query: 274 QDYRCAECRAPISLRGVPS---EARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRK 330
Q+YRCA C +R P R C+Y G+Y+C CH N IP+RV+ WDF
Sbjct: 672 QNYRCAGC----GIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYY 727
Query: 331 VSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKPYFITCREAMEA 390
VS S L + + P+ +++IN L+ V+ L ++R LR + MK F TCR A E
Sbjct: 728 VSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKE- 786
Query: 391 RLLLQLQDR--QHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKLDCERCQAKG 448
LL D H E+ +YS+ DL G LG L E+ A H++ C CQAKG
Sbjct: 787 --LLDSFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVE-RCMLCQAKG 843
Query: 449 FVCELCR-EGDVLFPFDSH-TSVCADCSAVFHRDCYYDNSTTCPKCARLSLRKQSLFQE 505
F+CE C+ E D++FPF+ H C +C A +H+ C+ S +CP+C RL R+++L ++
Sbjct: 844 FICEFCQNEDDIIFPFELHKCRTCEECKACYHKACF--KSGSCPRCERLQARREALARQ 900
>gi|150456467 hypothetical protein LOC9711 isoform 2 [Homo sapiens]
Length = 972
Score = 153 bits (387), Expect = 3e-37
Identities = 90/239 (37%), Positives = 130/239 (54%), Gaps = 17/239 (7%)
Query: 274 QDYRCAECRAPISLRGVPS---EARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRK 330
Q+YRCA C +R P R C+Y G+Y+C CH N IP+RV+ WDF
Sbjct: 717 QNYRCAGC----GIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYY 772
Query: 331 VSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKPYFITCREAMEA 390
VS S L + + P+ +++IN L+ V+ L ++R LR + MK F TCR A E
Sbjct: 773 VSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKE- 831
Query: 391 RLLLQLQDR--QHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKLDCERCQAKG 448
LL D H E+ +YS+ DL G LG L E+ A H++ C CQAKG
Sbjct: 832 --LLDSFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVE-RCMLCQAKG 888
Query: 449 FVCELCR-EGDVLFPFDSH-TSVCADCSAVFHRDCYYDNSTTCPKCARLSLRKQSLFQE 505
F+CE C+ E D++FPF+ H C +C A +H+ C+ S +CP+C RL R+++L ++
Sbjct: 889 FICEFCQNEDDIIFPFELHKCRTCEECKACYHKACF--KSGSCPRCERLQARREALARQ 945
>gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo
sapiens]
Length = 528
Score = 149 bits (376), Expect = 6e-36
Identities = 77/236 (32%), Positives = 125/236 (52%), Gaps = 4/236 (1%)
Query: 260 EYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPAR 319
+Y + I E GLDSQ CA C I V + C ++G YYC CH +D +VIPAR
Sbjct: 296 QYLVAIPMEKGLDSQGCFCAGCSRQIGFSFV--RPKLCAFSGLYYCDICHQDDASVIPAR 353
Query: 320 VVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKP 379
++HNWD R + R ++++L + ++P++ L+ +N L+ +VE + I + R+ + L+
Sbjct: 354 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGD 413
Query: 380 YFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKL 439
Y CR L +L R + +E+ + V DL + A + + FA
Sbjct: 414 YLGLCRSGALKELSKRLNHRNYLLESPHRFRVADLRQI-ADEVYEGFLKALIEFASQHVY 472
Query: 440 DCERCQAKGFVCELCREGDVLFPFDSHTSV-CADCSAVFHRDCYYDNSTTCPKCAR 494
C+ C + F+C++C+ D++FP + T+V CA C VFH+ C CP+CAR
Sbjct: 473 HCDLCTQRSFICQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528
>gi|156151402 hypothetical protein LOC80183 [Homo sapiens]
Length = 662
Score = 140 bits (353), Expect = 3e-33
Identities = 76/231 (32%), Positives = 126/231 (54%), Gaps = 6/231 (2%)
Query: 273 SQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVS 332
+Q++ CA C P+ + V R C+Y G+Y+C CH + IPAR++ WDF+ VS
Sbjct: 429 AQNFFCAGCGTPVEPKFV-KRLRYCEYLGKYFCDCCHSYAESCIPARILMMWDFKKYYVS 487
Query: 333 RCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKPYFITCREAMEARL 392
S + L + +P+ L I L++ +EL ++++++ + +K TCR A A
Sbjct: 488 NFSKQLLDSIWHQPIFNLLSIGQSLYAKAKELDRVKEIQEQLFHIKKLLKTCRFANSALK 547
Query: 393 LLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKLDCERCQAKGFVCE 452
+ Q H + ++S++DL+ + G L L +I H+ CE CQ KGF+CE
Sbjct: 548 EFE-QVPGHLTDELHLFSLEDLVRIKKGLLAPLLKDILKASLAHV-AGCELCQGKGFICE 605
Query: 453 LCREGDVLFPFDSHT-SVCADCSAVFHRDCYYDNSTTCPKCARLSLRKQSL 502
C+ V+FPF + T C+ C A FH+ C+ S+ CP+CAR++ R++ L
Sbjct: 606 FCQNTTVIFPFQTATCRRCSACRACFHKQCF--QSSECPRCARITARRKLL 654
>gi|239756837 PREDICTED: similar to pleckstrin homology domain
containing, family M (with RUN domain) member 1, partial
[Homo sapiens]
Length = 623
Score = 102 bits (253), Expect = 1e-21
Identities = 77/260 (29%), Positives = 121/260 (46%), Gaps = 32/260 (12%)
Query: 260 EYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPAR 319
+Y + I E GLDSQ CA C I V + C ++G YYC CH +D +VIPAR
Sbjct: 379 QYLVAIPMEKGLDSQGCFCAGCSRQIGFSFV--RPKLCAFSGLYYCDICHQDDASVIPAR 436
Query: 320 VVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKP 379
++HNWD R + R ++++L + ++P++ L+ +N L+ +VE + I + R+ + L+
Sbjct: 437 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGD 496
Query: 380 YFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKL 439
Y CR L +L R E S++ + L L E L A+ + L
Sbjct: 497 YLGLCRSG----ALKELSKR----AGPESASLKTASSI----LAAVLPEPGLLRAR-VCL 543
Query: 440 DCERCQAKGFVCELCREGDVLFP---------------FDSHTSVCADCSAVFHRDCYYD 484
+ ++G V L G L P D CA+C VFH+ C
Sbjct: 544 EQVPRGSQGVVKSL-GSGGALSPSLVKEPGTCTGMQTCVDQMPVGCAECKTVFHQSCQAV 602
Query: 485 NSTTCPKCA-RLSLRKQSLF 503
CP+CA R ++Q++F
Sbjct: 603 VKKGCPRCARRRKYQEQNIF 622
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 42.0 bits (97), Expect = 0.001
Identities = 13/48 (27%), Positives = 26/48 (54%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVSHQAEY 261
C +C ++WG+ + CT C +CH KC +L++ C+ +++
Sbjct: 655 CYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADCLQRAAEKSSKH 702
>gi|190684646 RAS guanyl releasing protein 1 isoform b [Homo
sapiens]
Length = 762
Score = 41.6 bits (96), Expect = 0.002
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
CD C +WG+I+ Y C C CH +C +L+ C
Sbjct: 520 CDNCAGFLWGVIKQGYRCKDCGMNCHKQCKDLVVFEC 556
>gi|190684644 RAS guanyl releasing protein 1 isoform a [Homo
sapiens]
Length = 797
Score = 41.6 bits (96), Expect = 0.002
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
CD C +WG+I+ Y C C CH +C +L+ C
Sbjct: 555 CDNCAGFLWGVIKQGYRCKDCGMNCHKQCKDLVVFEC 591
>gi|20149588 Ras association domain family 1 isoform A [Homo
sapiens]
Length = 340
Score = 40.8 bits (94), Expect = 0.003
Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 1/51 (1%)
Query: 200 HRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
HRF + + CD C IWG+++ C C + CH +C L+ C
Sbjct: 52 HRF-QPAGPATHTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRCRALVCLDC 101
>gi|40806175 diacylglycerol kinase, theta [Homo sapiens]
Length = 942
Score = 40.8 bits (94), Expect = 0.003
Identities = 31/119 (26%), Positives = 46/119 (38%), Gaps = 24/119 (20%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVS---------------HQ 258
C C+ IWGL + C C + H KCL + PC S S H+
Sbjct: 74 CHLCSDFIWGL--AGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPVAHCFGPRGLHK 131
Query: 259 AEYELNICPETGLDSQDYRCAECRAPISLRGVP---SEARQCDYTG--QYYCSHCHWND 312
++ +C + L++ C C + VP S+ RQC G + H HW +
Sbjct: 132 RKF-CAVCRKV-LEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHDTHHHHWRE 188
>gi|5453976 protein kinase C, theta [Homo sapiens]
Length = 706
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/95 (21%), Positives = 36/95 (37%), Gaps = 19/95 (20%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVSHQAEYELNICPETGLDS 273
C C+ +WGL + Y C C H KC++ + C S ++ + ET
Sbjct: 173 CSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSAINSR---------ETMFHK 223
Query: 274 QDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHC 308
+ ++ +P + +Y +C HC
Sbjct: 224 ERFKI----------DMPHRFKVYNYKSPTFCEHC 248
Score = 38.5 bits (88), Expect = 0.015
Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 195 RVLLEHRF--YKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC-V 251
++ + HRF Y KS + C+ C T++WGL + C C H +C ++ C +
Sbjct: 227 KIDMPHRFKVYNYKSPTF---CEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLCGI 283
Query: 252 SSKVSHQA 259
+ K+ +A
Sbjct: 284 NQKLMAEA 291
>gi|110611226 UNC13 (C. elegans)-like [Homo sapiens]
Length = 1591
Score = 40.0 bits (92), Expect = 0.005
Identities = 12/38 (31%), Positives = 23/38 (60%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCV 251
C +C ++WG+ + C+ C +CH KC +L++ C+
Sbjct: 491 CYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCL 528
>gi|213385270 RAS guanyl releasing protein 3 (calcium and
DAG-regulated) isoform 1 [Homo sapiens]
Length = 690
Score = 39.7 bits (91), Expect = 0.007
Identities = 13/37 (35%), Positives = 20/37 (54%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
C+ C +WG+I+ Y C C CH +C +L+ C
Sbjct: 508 CEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLAC 544
>gi|24762239 RAS guanyl releasing protein 3 (calcium and
DAG-regulated) isoform 1 [Homo sapiens]
Length = 690
Score = 39.7 bits (91), Expect = 0.007
Identities = 13/37 (35%), Positives = 20/37 (54%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
C+ C +WG+I+ Y C C CH +C +L+ C
Sbjct: 508 CEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLAC 544
>gi|7662334 RAS guanyl releasing protein 3 (calcium and
DAG-regulated) isoform 2 [Homo sapiens]
Length = 689
Score = 39.7 bits (91), Expect = 0.007
Identities = 13/37 (35%), Positives = 20/37 (54%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
C+ C +WG+I+ Y C C CH +C +L+ C
Sbjct: 507 CEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLAC 543
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 39.7 bits (91), Expect = 0.007
Identities = 12/48 (25%), Positives = 25/48 (52%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVSHQAEY 261
C +C ++WG+ + C C +CH KC +L++ C+ +++
Sbjct: 1111 CYECEGLLWGIARQGMKCLECGVKCHEKCQDLLNADCLQRAAEKSSKH 1158
>gi|13384594 protein kinase C, gamma [Homo sapiens]
Length = 697
Score = 39.3 bits (90), Expect = 0.009
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 185 KDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLN 244
K P D+P + H+F + S S CD C ++++GL+ C+ C H +C+
Sbjct: 90 KGPQTDDPRNK----HKF-RLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCVR 144
Query: 245 LISKPCVSSKVSHQAEYELNI 265
+ C + +L I
Sbjct: 145 SVPSLCGVDHTERRGRLQLEI 165
>gi|215820619 zinc finger protein 646 [Homo sapiens]
Length = 1832
Score = 38.9 bits (89), Expect = 0.011
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
Query: 249 PCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHC 308
P + ++ +H+ E + P T LD + Y+C+EC RG R TG+Y CS C
Sbjct: 442 PLLLAETTHKEEED----PTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGEYQCSLC 497
>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
sapiens]
Length = 1719
Score = 38.9 bits (89), Expect = 0.011
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 200 HRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVSHQA 259
H+F+ KS + C +C +++ GLI+ +C C + CH C+N P Q
Sbjct: 1000 HQFFV-KSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVN--KAPTTCPVPPEQT 1056
Query: 260 EYELNICPETGL 271
+ L I P+ G+
Sbjct: 1057 KGPLGIDPQKGI 1068
>gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo
sapiens]
Length = 1638
Score = 38.9 bits (89), Expect = 0.011
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 200 HRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVSHQA 259
H+F+ KS + C +C +++ GLI+ +C C + CH C+N P Q
Sbjct: 919 HQFFV-KSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVN--KAPTTCPVPPEQT 975
Query: 260 EYELNICPETGL 271
+ L I P+ G+
Sbjct: 976 KGPLGIDPQKGI 987
>gi|47157325 protein kinase C, delta [Homo sapiens]
Length = 676
Score = 38.5 bits (88), Expect = 0.015
Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
Query: 198 LEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
+ HRF K + CD C +++WGL++ C C H KC ++ C
Sbjct: 229 MPHRF-KVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLC 280
Score = 37.7 bits (86), Expect = 0.025
Identities = 23/95 (24%), Positives = 35/95 (36%), Gaps = 19/95 (20%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVSHQAEYELNICPETGLDS 273
C C +WGL + Y C C H KC++ I + C T +S
Sbjct: 172 CSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKI----------------IGRCTGTAANS 215
Query: 274 QDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHC 308
+D + R I + P + +Y +C HC
Sbjct: 216 RDTIFQKERFNIDM---PHRFKVHNYMSPTFCDHC 247
>gi|31377782 protein kinase C, delta [Homo sapiens]
Length = 676
Score = 38.5 bits (88), Expect = 0.015
Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
Query: 198 LEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
+ HRF K + CD C +++WGL++ C C H KC ++ C
Sbjct: 229 MPHRF-KVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLC 280
Score = 37.7 bits (86), Expect = 0.025
Identities = 23/95 (24%), Positives = 35/95 (36%), Gaps = 19/95 (20%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVSHQAEYELNICPETGLDS 273
C C +WGL + Y C C H KC++ I + C T +S
Sbjct: 172 CSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKI----------------IGRCTGTAANS 215
Query: 274 QDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHC 308
+D + R I + P + +Y +C HC
Sbjct: 216 RDTIFQKERFNIDM---PHRFKVHNYMSPTFCDHC 247
>gi|4885563 protein kinase C, epsilon [Homo sapiens]
Length = 737
Score = 38.1 bits (87), Expect = 0.019
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 179 LKLQELKDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRC 238
LK QE D + V + H+F K V CD C +++WGL++ C C
Sbjct: 223 LKKQETPDQVGSQ-RFSVNMPHKFGIHNYK-VPTFCDHCGSLLWGLLRQGLQCKVCKMNV 280
Query: 239 HSKCLNLISKPC-VSSKVSHQAEYELNICPE 268
H +C ++ C V ++ + +L + P+
Sbjct: 281 HRRCETNVAPNCGVDARGIAKVLADLGVTPD 311
Score = 32.3 bits (72), Expect = 1.1
Identities = 15/42 (35%), Positives = 18/42 (42%), Gaps = 1/42 (2%)
Query: 214 CDKCNTIIWGLI-QTWYTCTGCYYRCHSKCLNLISKPCVSSK 254
C C IWG+I + Y C C H +C LI C K
Sbjct: 183 CSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLK 224
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 38.1 bits (87), Expect = 0.019
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 195 RVLLEHR--FYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
R + EH + S+ Q+C++C + IW L+ C+ C CH KC++ I C
Sbjct: 1625 RAVQEHNGHVFASYQVSIPQSCEQCLSYIW-LMDKALLCSVCKMTCHKKCVHKIQSHC 1681
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 38.1 bits (87), Expect = 0.019
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 195 RVLLEHR--FYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
R + EH + S+ Q+C++C + IW L+ C+ C CH KC++ I C
Sbjct: 1625 RAVQEHNGHVFASYQVSIPQSCEQCLSYIW-LMDKALLCSVCKMTCHKKCVHKIQSHC 1681
>gi|26051258 RAS guanyl releasing protein 4 isoform a [Homo sapiens]
Length = 673
Score = 37.4 bits (85), Expect = 0.033
Identities = 12/37 (32%), Positives = 18/37 (48%)
Query: 214 CDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPC 250
CD C+ +WG+ + Y C C CH C + + C
Sbjct: 554 CDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVEC 590
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,216,240
Number of Sequences: 37866
Number of extensions: 1118804
Number of successful extensions: 3877
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 3714
Number of HSP's gapped (non-prelim): 231
length of query: 512
length of database: 18,247,518
effective HSP length: 107
effective length of query: 405
effective length of database: 14,195,856
effective search space: 5749321680
effective search space used: 5749321680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.