Guide to the Human Genome
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Search of human proteins with 46409360

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46409360 G protein-coupled receptor 148 [Homo sapiens]
         (347 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46409360 G protein-coupled receptor 148 [Homo sapiens]             701   0.0  
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap...    72   6e-13
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap...    68   1e-11
gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens]             64   2e-10
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]                 62   8e-10
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]                60   4e-09
gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]          59   6e-09
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                 57   3e-08
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...    55   7e-08
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa...    55   1e-07
gi|4557865 somatostatin receptor 5 [Homo sapiens]                      53   5e-07
gi|4557265 beta-1-adrenergic receptor [Homo sapiens]                   53   5e-07
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]     52   6e-07
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]     52   6e-07
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]     52   6e-07
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]     52   6e-07
gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa...    52   6e-07
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]                   52   6e-07
gi|16876435 G protein-coupled receptor 101 [Homo sapiens]              52   6e-07
gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]           52   8e-07
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]    51   2e-06
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]    51   2e-06
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]     51   2e-06
gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo sap...    50   2e-06
gi|57165371 G protein-coupled receptor 61 [Homo sapiens]               49   5e-06
gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens]                49   7e-06
gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens]                49   7e-06
gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens]                49   7e-06
gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens]                 49   7e-06
gi|15150803 opsin 4 isoform 1 [Homo sapiens]                           49   9e-06

>gi|46409360 G protein-coupled receptor 148 [Homo sapiens]
          Length = 347

 Score =  701 bits (1808), Expect = 0.0
 Identities = 347/347 (100%), Positives = 347/347 (100%)

Query: 1   MGDELAPCPVGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLA 60
           MGDELAPCPVGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLA
Sbjct: 1   MGDELAPCPVGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLA 60

Query: 61  AATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSLGGWELGRMA 120
           AATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSLGGWELGRMA
Sbjct: 61  AATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSLGGWELGRMA 120

Query: 121 CGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFP 180
           CGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFP
Sbjct: 121 CGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFP 180

Query: 181 TFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFW 240
           TFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFW
Sbjct: 181 TFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFW 240

Query: 241 RIYAEAKTSGIWGQGYSRARGTLLIHSVLITLYVSTGVVFSLDMVLTRYHHIDSGTHTWL 300
           RIYAEAKTSGIWGQGYSRARGTLLIHSVLITLYVSTGVVFSLDMVLTRYHHIDSGTHTWL
Sbjct: 241 RIYAEAKTSGIWGQGYSRARGTLLIHSVLITLYVSTGVVFSLDMVLTRYHHIDSGTHTWL 300

Query: 301 LAANSEVLMMLPRAMLPYLYLLRYRQLLGMVRGHLPSRRHQAIFTIS 347
           LAANSEVLMMLPRAMLPYLYLLRYRQLLGMVRGHLPSRRHQAIFTIS
Sbjct: 301 LAANSEVLMMLPRAMLPYLYLLRYRQLLGMVRGHLPSRRHQAIFTIS 347


>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
           sapiens]
          Length = 390

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 72/272 (26%), Positives = 118/272 (43%), Gaps = 31/272 (11%)

Query: 7   PCPVGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAV 66
           P P G+  W     L S       A S        +   S  L W  L   LLA  TLA 
Sbjct: 11  PPPAGSETWVPQANLSS-------APSQNCSAKDYIYQDSISLPWKVLLVMLLALITLAT 63

Query: 67  S---PLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISS--SSLGGWELGRMAC 121
           +     ++ T+ R ++L    +YL+ A++ ++DL   +L M IS+  +  G W LG++ C
Sbjct: 64  TLSNAFVIATVYRTRKLHTPANYLI-ASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVC 122

Query: 122 GILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWL--VACCF 179
                +    CT++IL    I L  Y A+   + Y +  +   A   +AL+W+  ++   
Sbjct: 123 DFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISL 182

Query: 180 PTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCF 239
           P F      W+ A+ EE+ +  ++             ++ T  S +   +  T L+   +
Sbjct: 183 PPFF-----WRQAKAEEEVSECVVNTDH---------ILYTVYSTVGAFYFPTLLLIALY 228

Query: 240 WRIYAEAKTSGIWGQGYSRARGTLLIHSVLIT 271
            RIY EA+ S I  Q  +R  G  L  + LIT
Sbjct: 229 GRIYVEAR-SRILKQTPNRT-GKRLTRAQLIT 258


>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
           sapiens]
          Length = 377

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 58/231 (25%), Positives = 102/231 (44%), Gaps = 27/231 (11%)

Query: 28  MPQAASNTSLGLG------DLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLR 81
           +PQ ASN SL         D R   ++   L +  S++  AT+  +  +L TIL  ++L 
Sbjct: 11  LPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLH 70

Query: 82  QEPHYLLPANILLSDLAYILLHMLISSSSL--GGWELGRMACGILTDAVFAACTSTILSF 139
              +YL+  ++  +DL   +L M IS +      W  G++ C I   +    CT++IL  
Sbjct: 71  TPANYLI-GSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHL 129

Query: 140 TAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCF---PTFLIWLSKWQDAQLEE 196
             I L  Y A+   L Y    + G A   +A++W ++ C    P F      W+ A+ +E
Sbjct: 130 CVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLF------WRQAKAQE 183

Query: 197 QGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIYAEAK 247
           + +  ++  S          +  T  S     ++ + L+   + RIY  A+
Sbjct: 184 EMSDCLVNTSQ---------ISYTIYSTCGAFYIPSVLLIILYGRIYRAAR 225


>gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens]
          Length = 357

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 67/229 (29%), Positives = 101/229 (44%), Gaps = 34/229 (14%)

Query: 33  SNTSLGLGDLRVPSSMLYWLFLPSSL-----LAAATLAVSPLLLVTILRNQRLRQEPHYL 87
           +N SLG  DLR PSS L  +F    L     L AAT A + L+L TILR +   + PH L
Sbjct: 20  TNHSLGKDDLR-PSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNL 78

Query: 88  LPANILLSDLAYILLHM---LISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAIVL 144
           + A++ +SD+    L M   L+   S   W+LGR  C +        CT++I + TAI L
Sbjct: 79  V-ASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIAL 137

Query: 145 HTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCF---PTFLIWLSKWQDAQLEEQGA-- 199
             Y ++   + Y        +   +AL W ++      P    W   + +   E Q +  
Sbjct: 138 DRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSRE 197

Query: 200 -SYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIYAEAK 247
            SY +  ++G            Y  +  VLF+        +W+IY  AK
Sbjct: 198 PSYAVFSTVG----------AFYLPLCVVLFV--------YWKIYKAAK 228


>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
          Length = 572

 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 57/215 (26%), Positives = 100/215 (46%), Gaps = 23/215 (10%)

Query: 52  LFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDL--AYILLHMLISSS 109
           +FL + +L A  +A + L+++++  N+ L+   +Y +  N+ ++DL  +  +L    +  
Sbjct: 101 VFLAAFILMA--VAGNLLVILSVACNRHLQTVTNYFI-VNLAVADLLLSATVLPFSATME 157

Query: 110 SLGGWELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAV 169
            LG W  GR  C +        CT++ILS   I +  Y+ V H L+Y + M+   A   +
Sbjct: 158 VLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAIL 217

Query: 170 ALIWLVACCFPTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYT--SILCV 227
           AL+W+VA         L  W++           +PP    +  CG+     Y   S +C 
Sbjct: 218 ALLWVVALVVSVGP--LLGWKEP----------VPPD---ERFCGITEEAGYAVFSSVCS 262

Query: 228 LFLCTALIANCFWRIYAEAK-TSGIWGQGYSRARG 261
            +L  A+I   + R+Y  A+ T+     G  R RG
Sbjct: 263 FYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERG 297


>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
          Length = 408

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 52/180 (28%), Positives = 86/180 (47%), Gaps = 11/180 (6%)

Query: 15  WPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAV---SPLLL 71
           WP     ++  P +P  A NT+   G   VP    +   L  +LLA A LA    + L++
Sbjct: 4   WPHENSSLAPWPDLPTLAPNTANTSGLPGVP----WEAALAGALLALAVLATVGGNLLVI 59

Query: 72  VTILRNQRLRQEPHYLLPANILLSDLAYILLHM--LISSSSLGGWELGRMACGILTDAVF 129
           V I    RL+   +  +  ++  +DL   LL +    + +  G W LG   C + T    
Sbjct: 60  VAIAWTPRLQTMTNVFV-TSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDV 118

Query: 130 AACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKW 189
              T++I +  A+ +  YLAV +PLRY + ++   A  AV L+W+V+    +F   +S+W
Sbjct: 119 LCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAV-SFAPIMSQW 177


>gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]
          Length = 460

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 50/202 (24%), Positives = 92/202 (45%), Gaps = 23/202 (11%)

Query: 54  LPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSL-- 111
           + + LL+ AT+  + L+L++   N  L+   +Y L  ++  +DL      M + ++ L  
Sbjct: 30  ITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFL-LSLACADLIIGTFSMNLYTTYLLM 88

Query: 112 GGWELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVAL 171
           G W LG +AC +     + A  +++++   I    Y +V  PL Y +  +   A   + L
Sbjct: 89  GHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGL 148

Query: 172 IWLVACCFPTFLIW---LSKWQDAQLEE---QGASYILPPSMGTQPGCGLLVIVTYTSIL 225
            WLV     +F++W   +  WQ    E     G  YI      +QP      I+T+ + +
Sbjct: 149 AWLV-----SFVLWAPAILFWQYLVGERTVLAGQCYI---QFLSQP------IITFGTAM 194

Query: 226 CVLFLCTALIANCFWRIYAEAK 247
              +L   ++   +WRIY E +
Sbjct: 195 AAFYLPVTVMCTLYWRIYRETE 216


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 60/248 (24%), Positives = 114/248 (45%), Gaps = 30/248 (12%)

Query: 30  QAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLP 89
           Q +SN++L    L +  ++   L L + +L A  +  + L+++++  N+ LR   +Y + 
Sbjct: 30  QTSSNSTLP--QLDITRAISVGLVLGAFILFA--IVGNILVILSVACNRHLRTPTNYFI- 84

Query: 90  ANILLSDL--AYILLHMLISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAIVLHTY 147
            N+ ++DL  ++ +L    +   LG W LGR+ C I        CT++ILS  AI +  Y
Sbjct: 85  VNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRY 144

Query: 148 LAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKWQDAQLEEQGASYILPPSM 207
           + V + L+Y + ++   A  A+  +W+++      +  L  W++             P+ 
Sbjct: 145 IGVRYSLQYPTLVTRRKAILALLSVWVLSTVIS--IGPLLGWKE-------------PAP 189

Query: 208 GTQPGCGLLVIVTYT--SILCVLFLCTALIANCFWRIYAEAK------TSGIWGQGYSRA 259
                CG+     Y   S L   ++  A+I   + R+Y  AK       +G+  +  +  
Sbjct: 190 NDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSK 249

Query: 260 RGTLLIHS 267
             TL IHS
Sbjct: 250 ELTLRIHS 257


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 60/227 (26%), Positives = 93/227 (40%), Gaps = 17/227 (7%)

Query: 29  PQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLL 88
           P A S  + G G    P     W+     ++ A T A + LL+  I     LR   ++ L
Sbjct: 7   PTANSTPAWGAGPPSAPGGS-GWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFL 65

Query: 89  PANILLSDLAYILLHM--LISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAIVLHT 146
             ++  SDL   L+ M   + ++  G W L R  C + T      C+++IL+   I L  
Sbjct: 66  -VSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDR 124

Query: 147 YLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKWQDAQLEEQGASYILPPS 206
           YL ++ PLRY   M+   A   V   W +A    +FL  L  W +         +  PP 
Sbjct: 125 YLLILSPLRYKLRMTPLRALALVLGAWSLA-ALASFLPLLLGWHE-------LGHARPPV 176

Query: 207 MGTQPGCGLLVIVTYTSILCVL--FLCTALIANCFWRIYAEAKTSGI 251
            G    C LL  + +  +   L  FL +  I   + RI   A+   +
Sbjct: 177 PGQ---CRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAV 220


>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
           sapiens]
          Length = 422

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 7/165 (4%)

Query: 25  TPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEP 84
           +P  P      + G+ D+ V   ++  L L  +L+  A L  +  ++  I   + L+   
Sbjct: 14  SPPAPFETGGNTTGISDVTVSYQVITSLLL-GTLIFCAVLG-NACVVAAIALERSLQNVA 71

Query: 85  HYLLPANILLSDL--AYILLHMLISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAI 142
           +YL+  ++ ++DL  + ++L M      L  W LG++ C +        CTS+IL   AI
Sbjct: 72  NYLI-GSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAI 130

Query: 143 VLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVA--CCFPTFLIW 185
            L  Y A+  P+ Y++  +   A   ++L WL+      P  L W
Sbjct: 131 ALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGW 175


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 60/264 (22%), Positives = 113/264 (42%), Gaps = 20/264 (7%)

Query: 23  SKTPCMPQAASNTSLGLGDLRV-----PSSMLYWLFLPSS--LLAAATLAVSPLLLVTIL 75
           + TP    ++   + G GD R      PS+    + +P    L+ AA L  + L++  +L
Sbjct: 7   ASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVL 66

Query: 76  RNQRLRQEPH-YLLPANILLSDLAYIL-LHMLISSSSLGGWELGRMACGILTDAVFAACT 133
           R  +++   + Y+L  N+ ++D+ Y+L L  L + ++   W  G + C ++         
Sbjct: 67  RFAKMKTVTNIYIL--NLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQF 124

Query: 134 STILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKWQDAQ 193
           +++   T + +  YLAV+HPL    +     A  A A  W+++ C    L+       A 
Sbjct: 125 TSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVF-----AD 179

Query: 194 LEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIYAEAKTSGIWG 253
           ++E G      P      G    V + YT++L   F    +I  C+  I  + + +G+  
Sbjct: 180 VQEGGTCNASWPE---PVGLWGAVFIIYTAVL-GFFAPLLVICLCYLLIVVKVRAAGVRV 235

Query: 254 QGYSRARGTLLIHSVLITLYVSTG 277
               R     +   VL+ + V  G
Sbjct: 236 GCVRRRSERKVTRMVLVVVLVFAG 259


>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
          Length = 477

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 46/195 (23%), Positives = 86/195 (44%), Gaps = 12/195 (6%)

Query: 57  SLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSL--GGW 114
           +L+    +A + L++V I +  RL+   +  +  ++  +DL   LL +   ++ +  G W
Sbjct: 66  ALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFI-MSLASADLVMGLLVVPFGATIVVWGRW 124

Query: 115 ELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWL 174
           E G   C + T       T++I +   I L  YLA+  P RY S ++   A   V  +W 
Sbjct: 125 EYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWA 184

Query: 175 VACCFPTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTY--TSILCVLFLCT 232
           ++    +FL  L  W  A+ +E    Y  P        C  +    Y   S +   ++  
Sbjct: 185 IS-ALVSFLPILMHWWRAESDEARRCYNDPKC------CDFVTNRAYAIASSVVSFYVPL 237

Query: 233 ALIANCFWRIYAEAK 247
            ++A  + R++ EA+
Sbjct: 238 CIMAFVYLRVFREAQ 252


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 22/184 (11%)

Query: 69  LLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISS--SSLGGWELGRMACGILTD 126
           L+++++  ++ L    HY +  N+ ++DL      +  S+    LG W  GR+ C I   
Sbjct: 46  LVILSVACHRHLHSVTHYYI-VNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAA 104

Query: 127 AVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW---LVACCFPTFL 183
                CT++I+    I +  Y+ V +PLRY + ++      A+  +W   LV    P F 
Sbjct: 105 VDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF- 163

Query: 184 IWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIY 243
                W+    E++    I       +PG  L       S L   +L  A+I   + R+Y
Sbjct: 164 ----GWRQPAPEDETICQI-----NEEPGYVLF------SALGSFYLPLAIILVMYCRVY 208

Query: 244 AEAK 247
             AK
Sbjct: 209 VVAK 212


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 22/184 (11%)

Query: 69  LLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISS--SSLGGWELGRMACGILTD 126
           L+++++  ++ L    HY +  N+ ++DL      +  S+    LG W  GR+ C I   
Sbjct: 46  LVILSVACHRHLHSVTHYYI-VNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAA 104

Query: 127 AVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW---LVACCFPTFL 183
                CT++I+    I +  Y+ V +PLRY + ++      A+  +W   LV    P F 
Sbjct: 105 VDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF- 163

Query: 184 IWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIY 243
                W+    E++    I       +PG  L       S L   +L  A+I   + R+Y
Sbjct: 164 ----GWRQPAPEDETICQI-----NEEPGYVLF------SALGSFYLPLAIILVMYCRVY 208

Query: 244 AEAK 247
             AK
Sbjct: 209 VVAK 212


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 22/184 (11%)

Query: 69  LLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISS--SSLGGWELGRMACGILTD 126
           L+++++  ++ L    HY +  N+ ++DL      +  S+    LG W  GR+ C I   
Sbjct: 46  LVILSVACHRHLHSVTHYYI-VNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAA 104

Query: 127 AVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW---LVACCFPTFL 183
                CT++I+    I +  Y+ V +PLRY + ++      A+  +W   LV    P F 
Sbjct: 105 VDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF- 163

Query: 184 IWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIY 243
                W+    E++    I       +PG  L       S L   +L  A+I   + R+Y
Sbjct: 164 ----GWRQPAPEDETICQI-----NEEPGYVLF------SALGSFYLPLAIILVMYCRVY 208

Query: 244 AEAK 247
             AK
Sbjct: 209 VVAK 212


>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
          Length = 429

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 22/184 (11%)

Query: 69  LLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISS--SSLGGWELGRMACGILTD 126
           L+++++  ++ L    HY +  N+ ++DL      +  S+    LG W  GR+ C I   
Sbjct: 46  LVILSVACHRHLHSVTHYYI-VNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAA 104

Query: 127 AVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW---LVACCFPTFL 183
                CT++I+    I +  Y+ V +PLRY + ++      A+  +W   LV    P F 
Sbjct: 105 VDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF- 163

Query: 184 IWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIY 243
                W+    E++    I       +PG  L       S L   +L  A+I   + R+Y
Sbjct: 164 ----GWRQPAPEDETICQI-----NEEPGYVLF------SALGSFYLPLAIILVMYCRVY 208

Query: 244 AEAK 247
             AK
Sbjct: 209 VVAK 212


>gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo
           sapiens]
          Length = 366

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 49/211 (23%), Positives = 88/211 (41%), Gaps = 24/211 (11%)

Query: 43  RVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILL 102
           R+PS +L  L L  S LA  T  ++ L++  I+  ++L    +YL+  ++ ++D    +L
Sbjct: 19  RMPSKILVSLTL--SGLALMTTTINSLVIAAIIVTRKLHHPANYLI-CSLAVTDFLVAVL 75

Query: 103 HMLISSSSL--GGWELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFM 160
            M  S   +    W +G++ C I        CT +IL  +AI L  Y A+   + Y    
Sbjct: 76  VMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKR 135

Query: 161 SHGAAWKAVALIWLVACCF---PTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLV 217
           +   A   + ++W+++      P F      W+           I              +
Sbjct: 136 TPKHAGIMITIVWIISVFISMPPLF------WRHQGTSRDDECIIKHDH----------I 179

Query: 218 IVTYTSILCVLFLCTALIANCFWRIYAEAKT 248
           + T  S     ++  ALI   +++IY  AKT
Sbjct: 180 VSTIYSTFGAFYIPLALILILYYKIYRAAKT 210


>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
          Length = 384

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 60/286 (20%), Positives = 120/286 (41%), Gaps = 28/286 (9%)

Query: 41  DLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDL--A 98
           D  +P +M++ L L    +    ++ +  L++ IL+ + +R   + L+  N+  SDL  A
Sbjct: 32  DCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILI-VNLSFSDLLVA 90

Query: 99  YILLHMLISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLS 158
            + L      + +  W  G   C +       + T +I S   I +  +  +I+P  +  
Sbjct: 91  IMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRP 150

Query: 159 FMSHGAAWKAVALIWLVACCFPT-FLIWL----SKWQDAQLEEQGASYI----LPPSMGT 209
              H  A+  +A+IW++A      FLI+       +Q+  L+     Y+     P     
Sbjct: 151 NNRH--AYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHR 208

Query: 210 QPGCGLLVIVTYTSILCVLFLCTALIANCFWRIYAEAKTSG----IWGQGYSRARGTLLI 265
                LL+++ Y   LC +F+       C+++IY   K              R+  T  I
Sbjct: 209 LSYTTLLLVLQYFGPLCFIFI-------CYFKIYIRLKRRNNMMDKMRDNKYRSSETKRI 261

Query: 266 HSVLITLYVSTGVVFSLDMVLTRYHHIDSGTHTWLLAANSEVLMML 311
           + +L+++ V+  V +   + LT ++ +    H  +   N  +L +L
Sbjct: 262 NIMLLSIVVAFAVCW---LPLTIFNTVFDWNHQIIATCNHNLLFLL 304


>gi|16876435 G protein-coupled receptor 101 [Homo sapiens]
          Length = 508

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 54/216 (25%), Positives = 96/216 (44%), Gaps = 17/216 (7%)

Query: 23  SKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQ 82
           S   CMP +    SL  G +R   S +  +FL +S +    LA     LV   + Q L+ 
Sbjct: 14  SSHTCMPLSKMPISLAHGIIR---STVLVIFLAASFVGNIVLA-----LVLQRKPQLLQV 65

Query: 83  EPHYLLPANILLSDLAYILL--HMLISSSSLGGWELGRMACGILTDAVFAACTSTILSFT 140
              ++   N+L++DL  I L    ++++S    W L    C  L         +++ +  
Sbjct: 66  TNRFIF--NLLVTDLLQISLVAPWVVATSVPLFWPLNSHFCTALVSLTHLFAFASVNTIV 123

Query: 141 AIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKWQDAQLEEQGAS 200
            + +  YL++IHPL Y S M+    +  +   W+VA    T  ++   W  A  +E+ A 
Sbjct: 124 VVSVDRYLSIIHPLSYPSKMTQRRGYLLLYGTWIVAILQSTPPLY--GWGQAAFDERNA- 180

Query: 201 YILPPSMGTQPGCGLLVIVTYTSI-LCVLFLCTALI 235
            +     G  P   +L +V++  I L V+  C +++
Sbjct: 181 -LCSMIWGASPSYTILSVVSFIVIPLIVMIACYSVV 215


>gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]
          Length = 590

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 39/196 (19%), Positives = 87/196 (44%), Gaps = 15/196 (7%)

Query: 56  SSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDL--AYILLHMLISSSSLGG 113
           + +LA  T+  + L++V+   N++L+   +Y L  ++  +DL    I +++  +   +  
Sbjct: 75  TGILALVTIIGNILVIVSFKVNKQLKTVNNYFL-LSLACADLIIGVISMNLFTTYIIMNR 133

Query: 114 WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW 173
           W LG +AC +     + A  +++++   I    Y ++  PL Y +  +   A   + L W
Sbjct: 134 WALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAW 193

Query: 174 LVACCF--PTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLC 231
           +++     P  L W   +   +    G  +I   S  T         +T+ + +   ++ 
Sbjct: 194 VISFVLWAPAILFW-QYFVGKRTVPPGECFIQFLSEPT---------ITFGTAIAAFYMP 243

Query: 232 TALIANCFWRIYAEAK 247
             ++   +WRIY E +
Sbjct: 244 VTIMTILYWRIYKETE 259


>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
          Length = 432

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 34/140 (24%), Positives = 66/140 (47%), Gaps = 6/140 (4%)

Query: 57  SLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHM-LISSSSL--GG 113
           +L+   T+A + L+++++   ++LRQ  +YL+  ++ L+DL+  +  M  +S + L  G 
Sbjct: 89  TLITLLTIAGNCLVVISVCFVKKLRQPSNYLI-VSLALADLSVAVAVMPFVSVTDLIGGK 147

Query: 114 WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW 173
           W  G   C +        CT++I++   I +  YL +  PL Y    +     K +  +W
Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207

Query: 174 LVAC--CFPTFLIWLSKWQD 191
           L++     P    W     D
Sbjct: 208 LLSASITLPPLFGWAQNVND 227


>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
          Length = 479

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 34/140 (24%), Positives = 66/140 (47%), Gaps = 6/140 (4%)

Query: 57  SLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHM-LISSSSL--GG 113
           +L+   T+A + L+++++   ++LRQ  +YL+  ++ L+DL+  +  M  +S + L  G 
Sbjct: 89  TLITLLTIAGNCLVVISVCFVKKLRQPSNYLI-VSLALADLSVAVAVMPFVSVTDLIGGK 147

Query: 114 WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW 173
           W  G   C +        CT++I++   I +  YL +  PL Y    +     K +  +W
Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207

Query: 174 LVAC--CFPTFLIWLSKWQD 191
           L++     P    W     D
Sbjct: 208 LLSASITLPPLFGWAQNVND 227


>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
          Length = 445

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 34/140 (24%), Positives = 66/140 (47%), Gaps = 6/140 (4%)

Query: 57  SLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHM-LISSSSL--GG 113
           +L+   T+A + L+++++   ++LRQ  +YL+  ++ L+DL+  +  M  +S + L  G 
Sbjct: 89  TLITLLTIAGNCLVVISVCFVKKLRQPSNYLI-VSLALADLSVAVAVMPFVSVTDLIGGK 147

Query: 114 WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW 173
           W  G   C +        CT++I++   I +  YL +  PL Y    +     K +  +W
Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207

Query: 174 LVAC--CFPTFLIWLSKWQD 191
           L++     P    W     D
Sbjct: 208 LLSASITLPPLFGWAQNVND 227


>gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo
           sapiens]
          Length = 458

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 39/170 (22%), Positives = 77/170 (45%), Gaps = 6/170 (3%)

Query: 10  VGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPL 69
           +G   W   I  +S    +     NTS G G  + P  +  W  L   ++   T+  + L
Sbjct: 16  IGLLVWQCDIS-VSPVAAIVTDIFNTSDG-GRFKFPDGVQNWPALSIVIIIIMTIGGNIL 73

Query: 70  LLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSL---GGWELGRMACGILTD 126
           +++ +   ++L    +Y L  ++ ++D+   LL M +S  ++     W L R  C +   
Sbjct: 74  VIMAVSMEKKLHNATNYFL-MSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWIS 132

Query: 127 AVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVA 176
                 T++I+   AI L  Y+A+ +P+ +  F S   A   +A++W ++
Sbjct: 133 LDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAIS 182


>gi|57165371 G protein-coupled receptor 61 [Homo sapiens]
          Length = 451

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 59/231 (25%), Positives = 98/231 (42%), Gaps = 34/231 (14%)

Query: 22  ISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLR 81
           + +TP    A+    +GL D+   S  L+++ L      A   AV    +  I +   LR
Sbjct: 19  VPQTPGPSTASGVPEVGLRDVASESVALFFMLLLDLTAVAGNAAV----MAVIAKTPALR 74

Query: 82  QEPHYLLPANILLSDLAYILLHM---LISSSSLGGWEL-GRMACGILTDAVFAACTSTIL 137
           +   ++   ++ L DL   L  M   ++SSS+L    L G +AC +         +  IL
Sbjct: 75  K---FVFVFHLCLVDLLAALTLMPLAMLSSSALFDHALFGEVACRLYLFLSVCFVSLAIL 131

Query: 138 SFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTF-LIWLSKWQDAQLEE 196
           S +AI +  Y  V+HP+RY   M+ G     +  +W+ A    +  ++    W      E
Sbjct: 132 SVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVSW------E 185

Query: 197 QGASYILPPSMGTQPGCGL---------LVIVTYTSILCVLFLCTALIANC 238
           +GA     PS+   PGC L         L +V +  +  +L L   L+  C
Sbjct: 186 EGA-----PSV--PPGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYC 229


>gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens]
          Length = 328

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 55/196 (28%), Positives = 84/196 (42%), Gaps = 17/196 (8%)

Query: 52  LFLPS--SLLAAATLAVSPLLLVTILRNQR-LRQEPHYLLPANILLSDLAYIL-LHMLIS 107
           L LP   S + AA L ++  ++  I  ++R L +   Y L  N+ L+DL Y   L +LI 
Sbjct: 27  LLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTL--NLALADLLYACSLPLLIY 84

Query: 108 SSSLGG-WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLR-YLSFMSHGAA 165
           + + G  W  G  AC ++    +A    +IL  T I    YL + HPL  +       AA
Sbjct: 85  NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAA 144

Query: 166 WKAVALIWLVAC--CFPTFLIWLSKWQDAQLEEQGASYIL-PPSMGT--QPGCGLLVIVT 220
           W     +WL     C PT +   +  Q      +   Y L PP++ T   P    L ++ 
Sbjct: 145 WLVCVAVWLAVTTQCLPTAIFAATGIQ----RNRTVCYDLSPPALATHYMPYGMALTVIG 200

Query: 221 YTSILCVLFLCTALIA 236
           +      L  C  L+A
Sbjct: 201 FLLPFAALLACYCLLA 216


>gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens]
          Length = 328

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 55/196 (28%), Positives = 84/196 (42%), Gaps = 17/196 (8%)

Query: 52  LFLPS--SLLAAATLAVSPLLLVTILRNQR-LRQEPHYLLPANILLSDLAYIL-LHMLIS 107
           L LP   S + AA L ++  ++  I  ++R L +   Y L  N+ L+DL Y   L +LI 
Sbjct: 27  LLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTL--NLALADLLYACSLPLLIY 84

Query: 108 SSSLGG-WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLR-YLSFMSHGAA 165
           + + G  W  G  AC ++    +A    +IL  T I    YL + HPL  +       AA
Sbjct: 85  NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAA 144

Query: 166 WKAVALIWLVAC--CFPTFLIWLSKWQDAQLEEQGASYIL-PPSMGT--QPGCGLLVIVT 220
           W     +WL     C PT +   +  Q      +   Y L PP++ T   P    L ++ 
Sbjct: 145 WLVCVAVWLAVTTQCLPTAIFAATGIQ----RNRTVCYDLSPPALATHYMPYGMALTVIG 200

Query: 221 YTSILCVLFLCTALIA 236
           +      L  C  L+A
Sbjct: 201 FLLPFAALLACYCLLA 216


>gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens]
          Length = 328

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 55/196 (28%), Positives = 84/196 (42%), Gaps = 17/196 (8%)

Query: 52  LFLPS--SLLAAATLAVSPLLLVTILRNQR-LRQEPHYLLPANILLSDLAYIL-LHMLIS 107
           L LP   S + AA L ++  ++  I  ++R L +   Y L  N+ L+DL Y   L +LI 
Sbjct: 27  LLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTL--NLALADLLYACSLPLLIY 84

Query: 108 SSSLGG-WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLR-YLSFMSHGAA 165
           + + G  W  G  AC ++    +A    +IL  T I    YL + HPL  +       AA
Sbjct: 85  NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAA 144

Query: 166 WKAVALIWLVAC--CFPTFLIWLSKWQDAQLEEQGASYIL-PPSMGT--QPGCGLLVIVT 220
           W     +WL     C PT +   +  Q      +   Y L PP++ T   P    L ++ 
Sbjct: 145 WLVCVAVWLAVTTQCLPTAIFAATGIQ----RNRTVCYDLSPPALATHYMPYGMALTVIG 200

Query: 221 YTSILCVLFLCTALIA 236
           +      L  C  L+A
Sbjct: 201 FLLPFAALLACYCLLA 216


>gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens]
          Length = 328

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 55/196 (28%), Positives = 84/196 (42%), Gaps = 17/196 (8%)

Query: 52  LFLPS--SLLAAATLAVSPLLLVTILRNQR-LRQEPHYLLPANILLSDLAYIL-LHMLIS 107
           L LP   S + AA L ++  ++  I  ++R L +   Y L  N+ L+DL Y   L +LI 
Sbjct: 27  LLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTL--NLALADLLYACSLPLLIY 84

Query: 108 SSSLGG-WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLR-YLSFMSHGAA 165
           + + G  W  G  AC ++    +A    +IL  T I    YL + HPL  +       AA
Sbjct: 85  NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAA 144

Query: 166 WKAVALIWLVAC--CFPTFLIWLSKWQDAQLEEQGASYIL-PPSMGT--QPGCGLLVIVT 220
           W     +WL     C PT +   +  Q      +   Y L PP++ T   P    L ++ 
Sbjct: 145 WLVCVAVWLAVTTQCLPTAIFAATGIQ----RNRTVCYDLSPPALATHYMPYGMALTVIG 200

Query: 221 YTSILCVLFLCTALIA 236
           +      L  C  L+A
Sbjct: 201 FLLPFAALLACYCLLA 216


>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
          Length = 478

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 58/251 (23%), Positives = 98/251 (39%), Gaps = 17/251 (6%)

Query: 17  ALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILR 76
           +L +L S +P  P   +   + L  + VP    Y L     L+    +  +  ++ T  R
Sbjct: 38  SLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCR 97

Query: 77  NQRLRQEPHYLLPANILLSD--LAYILLHMLISSSSLGGWELGRMACGILTDAVFAACTS 134
           ++ LR  P  +   N+ +SD  +++    +  +SS    W  G   C            S
Sbjct: 98  SRSLRT-PANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGIS 156

Query: 135 TILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCF--PTFLIWLSKWQDA 192
           ++++ TAI L  YL +  PL      S   A   +  +WL A  +  P F  W +   + 
Sbjct: 157 SMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEG 216

Query: 193 QLEEQGASYILPPSMGTQPGCGLLVIVTYTSILC--VLFLCTALIANCFWRIYAEAKTSG 250
            L      Y     M   P      +  YT +LC  V FL   +I  C+  I+   + +G
Sbjct: 217 LLTSCSWDY-----MSFTP-----AVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETG 266

Query: 251 IWGQGYSRARG 261
              Q +   +G
Sbjct: 267 RALQTFGACKG 277


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.138    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,804,346
Number of Sequences: 37866
Number of extensions: 525382
Number of successful extensions: 2223
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 188
Number of HSP's successfully gapped in prelim test: 266
Number of HSP's that attempted gapping in prelim test: 1920
Number of HSP's gapped (non-prelim): 488
length of query: 347
length of database: 18,247,518
effective HSP length: 103
effective length of query: 244
effective length of database: 14,347,320
effective search space: 3500746080
effective search space used: 3500746080
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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