BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|46409360 G protein-coupled receptor 148 [Homo sapiens] (347 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|46409360 G protein-coupled receptor 148 [Homo sapiens] 701 0.0 gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 72 6e-13 gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap... 68 1e-11 gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens] 64 2e-10 gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 62 8e-10 gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 60 4e-09 gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens] 59 6e-09 gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 57 3e-08 gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 55 7e-08 gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 55 1e-07 gi|4557865 somatostatin receptor 5 [Homo sapiens] 53 5e-07 gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 53 5e-07 gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 52 6e-07 gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 52 6e-07 gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 52 6e-07 gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 52 6e-07 gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa... 52 6e-07 gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 52 6e-07 gi|16876435 G protein-coupled receptor 101 [Homo sapiens] 52 6e-07 gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens] 52 8e-07 gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 51 2e-06 gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 51 2e-06 gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 51 2e-06 gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo sap... 50 2e-06 gi|57165371 G protein-coupled receptor 61 [Homo sapiens] 49 5e-06 gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens] 49 7e-06 gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens] 49 7e-06 gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens] 49 7e-06 gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens] 49 7e-06 gi|15150803 opsin 4 isoform 1 [Homo sapiens] 49 9e-06 >gi|46409360 G protein-coupled receptor 148 [Homo sapiens] Length = 347 Score = 701 bits (1808), Expect = 0.0 Identities = 347/347 (100%), Positives = 347/347 (100%) Query: 1 MGDELAPCPVGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLA 60 MGDELAPCPVGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLA Sbjct: 1 MGDELAPCPVGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLA 60 Query: 61 AATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSLGGWELGRMA 120 AATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSLGGWELGRMA Sbjct: 61 AATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSLGGWELGRMA 120 Query: 121 CGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFP 180 CGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFP Sbjct: 121 CGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFP 180 Query: 181 TFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFW 240 TFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFW Sbjct: 181 TFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFW 240 Query: 241 RIYAEAKTSGIWGQGYSRARGTLLIHSVLITLYVSTGVVFSLDMVLTRYHHIDSGTHTWL 300 RIYAEAKTSGIWGQGYSRARGTLLIHSVLITLYVSTGVVFSLDMVLTRYHHIDSGTHTWL Sbjct: 241 RIYAEAKTSGIWGQGYSRARGTLLIHSVLITLYVSTGVVFSLDMVLTRYHHIDSGTHTWL 300 Query: 301 LAANSEVLMMLPRAMLPYLYLLRYRQLLGMVRGHLPSRRHQAIFTIS 347 LAANSEVLMMLPRAMLPYLYLLRYRQLLGMVRGHLPSRRHQAIFTIS Sbjct: 301 LAANSEVLMMLPRAMLPYLYLLRYRQLLGMVRGHLPSRRHQAIFTIS 347 >gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sapiens] Length = 390 Score = 72.4 bits (176), Expect = 6e-13 Identities = 72/272 (26%), Positives = 118/272 (43%), Gaps = 31/272 (11%) Query: 7 PCPVGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAV 66 P P G+ W L S A S + S L W L LLA TLA Sbjct: 11 PPPAGSETWVPQANLSS-------APSQNCSAKDYIYQDSISLPWKVLLVMLLALITLAT 63 Query: 67 S---PLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISS--SSLGGWELGRMAC 121 + ++ T+ R ++L +YL+ A++ ++DL +L M IS+ + G W LG++ C Sbjct: 64 TLSNAFVIATVYRTRKLHTPANYLI-ASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVC 122 Query: 122 GILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWL--VACCF 179 + CT++IL I L Y A+ + Y + + A +AL+W+ ++ Sbjct: 123 DFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISL 182 Query: 180 PTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCF 239 P F W+ A+ EE+ + ++ ++ T S + + T L+ + Sbjct: 183 PPFF-----WRQAKAEEEVSECVVNTDH---------ILYTVYSTVGAFYFPTLLLIALY 228 Query: 240 WRIYAEAKTSGIWGQGYSRARGTLLIHSVLIT 271 RIY EA+ S I Q +R G L + LIT Sbjct: 229 GRIYVEAR-SRILKQTPNRT-GKRLTRAQLIT 258 >gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sapiens] Length = 377 Score = 68.2 bits (165), Expect = 1e-11 Identities = 58/231 (25%), Positives = 102/231 (44%), Gaps = 27/231 (11%) Query: 28 MPQAASNTSLGLG------DLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLR 81 +PQ ASN SL D R ++ L + S++ AT+ + +L TIL ++L Sbjct: 11 LPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLH 70 Query: 82 QEPHYLLPANILLSDLAYILLHMLISSSSL--GGWELGRMACGILTDAVFAACTSTILSF 139 +YL+ ++ +DL +L M IS + W G++ C I + CT++IL Sbjct: 71 TPANYLI-GSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHL 129 Query: 140 TAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCF---PTFLIWLSKWQDAQLEE 196 I L Y A+ L Y + G A +A++W ++ C P F W+ A+ +E Sbjct: 130 CVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLF------WRQAKAQE 183 Query: 197 QGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIYAEAK 247 + + ++ S + T S ++ + L+ + RIY A+ Sbjct: 184 EMSDCLVNTSQ---------ISYTIYSTCGAFYIPSVLLIILYGRIYRAAR 225 >gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens] Length = 357 Score = 63.9 bits (154), Expect = 2e-10 Identities = 67/229 (29%), Positives = 101/229 (44%), Gaps = 34/229 (14%) Query: 33 SNTSLGLGDLRVPSSMLYWLFLPSSL-----LAAATLAVSPLLLVTILRNQRLRQEPHYL 87 +N SLG DLR PSS L +F L L AAT A + L+L TILR + + PH L Sbjct: 20 TNHSLGKDDLR-PSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNL 78 Query: 88 LPANILLSDLAYILLHM---LISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAIVL 144 + A++ +SD+ L M L+ S W+LGR C + CT++I + TAI L Sbjct: 79 V-ASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIAL 137 Query: 145 HTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCF---PTFLIWLSKWQDAQLEEQGA-- 199 Y ++ + Y + +AL W ++ P W + + E Q + Sbjct: 138 DRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSRE 197 Query: 200 -SYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIYAEAK 247 SY + ++G Y + VLF+ +W+IY AK Sbjct: 198 PSYAVFSTVG----------AFYLPLCVVLFV--------YWKIYKAAK 228 >gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] Length = 572 Score = 62.0 bits (149), Expect = 8e-10 Identities = 57/215 (26%), Positives = 100/215 (46%), Gaps = 23/215 (10%) Query: 52 LFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDL--AYILLHMLISSS 109 +FL + +L A +A + L+++++ N+ L+ +Y + N+ ++DL + +L + Sbjct: 101 VFLAAFILMA--VAGNLLVILSVACNRHLQTVTNYFI-VNLAVADLLLSATVLPFSATME 157 Query: 110 SLGGWELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAV 169 LG W GR C + CT++ILS I + Y+ V H L+Y + M+ A + Sbjct: 158 VLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAIL 217 Query: 170 ALIWLVACCFPTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYT--SILCV 227 AL+W+VA L W++ +PP + CG+ Y S +C Sbjct: 218 ALLWVVALVVSVGP--LLGWKEP----------VPPD---ERFCGITEEAGYAVFSSVCS 262 Query: 228 LFLCTALIANCFWRIYAEAK-TSGIWGQGYSRARG 261 +L A+I + R+Y A+ T+ G R RG Sbjct: 263 FYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERG 297 >gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] Length = 408 Score = 59.7 bits (143), Expect = 4e-09 Identities = 52/180 (28%), Positives = 86/180 (47%), Gaps = 11/180 (6%) Query: 15 WPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAV---SPLLL 71 WP ++ P +P A NT+ G VP + L +LLA A LA + L++ Sbjct: 4 WPHENSSLAPWPDLPTLAPNTANTSGLPGVP----WEAALAGALLALAVLATVGGNLLVI 59 Query: 72 VTILRNQRLRQEPHYLLPANILLSDLAYILLHM--LISSSSLGGWELGRMACGILTDAVF 129 V I RL+ + + ++ +DL LL + + + G W LG C + T Sbjct: 60 VAIAWTPRLQTMTNVFV-TSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDV 118 Query: 130 AACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKW 189 T++I + A+ + YLAV +PLRY + ++ A AV L+W+V+ +F +S+W Sbjct: 119 LCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAV-SFAPIMSQW 177 >gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens] Length = 460 Score = 58.9 bits (141), Expect = 6e-09 Identities = 50/202 (24%), Positives = 92/202 (45%), Gaps = 23/202 (11%) Query: 54 LPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSL-- 111 + + LL+ AT+ + L+L++ N L+ +Y L ++ +DL M + ++ L Sbjct: 30 ITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFL-LSLACADLIIGTFSMNLYTTYLLM 88 Query: 112 GGWELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVAL 171 G W LG +AC + + A +++++ I Y +V PL Y + + A + L Sbjct: 89 GHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGL 148 Query: 172 IWLVACCFPTFLIW---LSKWQDAQLEE---QGASYILPPSMGTQPGCGLLVIVTYTSIL 225 WLV +F++W + WQ E G YI +QP I+T+ + + Sbjct: 149 AWLV-----SFVLWAPAILFWQYLVGERTVLAGQCYI---QFLSQP------IITFGTAM 194 Query: 226 CVLFLCTALIANCFWRIYAEAK 247 +L ++ +WRIY E + Sbjct: 195 AAFYLPVTVMCTLYWRIYRETE 216 >gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] Length = 520 Score = 56.6 bits (135), Expect = 3e-08 Identities = 60/248 (24%), Positives = 114/248 (45%), Gaps = 30/248 (12%) Query: 30 QAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLP 89 Q +SN++L L + ++ L L + +L A + + L+++++ N+ LR +Y + Sbjct: 30 QTSSNSTLP--QLDITRAISVGLVLGAFILFA--IVGNILVILSVACNRHLRTPTNYFI- 84 Query: 90 ANILLSDL--AYILLHMLISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAIVLHTY 147 N+ ++DL ++ +L + LG W LGR+ C I CT++ILS AI + Y Sbjct: 85 VNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRY 144 Query: 148 LAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKWQDAQLEEQGASYILPPSM 207 + V + L+Y + ++ A A+ +W+++ + L W++ P+ Sbjct: 145 IGVRYSLQYPTLVTRRKAILALLSVWVLSTVIS--IGPLLGWKE-------------PAP 189 Query: 208 GTQPGCGLLVIVTYT--SILCVLFLCTALIANCFWRIYAEAK------TSGIWGQGYSRA 259 CG+ Y S L ++ A+I + R+Y AK +G+ + + Sbjct: 190 NDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSK 249 Query: 260 RGTLLIHS 267 TL IHS Sbjct: 250 ELTLRIHS 257 >gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapiens] Length = 440 Score = 55.5 bits (132), Expect = 7e-08 Identities = 60/227 (26%), Positives = 93/227 (40%), Gaps = 17/227 (7%) Query: 29 PQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLL 88 P A S + G G P W+ ++ A T A + LL+ I LR ++ L Sbjct: 7 PTANSTPAWGAGPPSAPGGS-GWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFL 65 Query: 89 PANILLSDLAYILLHM--LISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAIVLHT 146 ++ SDL L+ M + ++ G W L R C + T C+++IL+ I L Sbjct: 66 -VSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDR 124 Query: 147 YLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKWQDAQLEEQGASYILPPS 206 YL ++ PLRY M+ A V W +A +FL L W + + PP Sbjct: 125 YLLILSPLRYKLRMTPLRALALVLGAWSLA-ALASFLPLLLGWHE-------LGHARPPV 176 Query: 207 MGTQPGCGLLVIVTYTSILCVL--FLCTALIANCFWRIYAEAKTSGI 251 G C LL + + + L FL + I + RI A+ + Sbjct: 177 PGQ---CRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAV 220 >gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sapiens] Length = 422 Score = 54.7 bits (130), Expect = 1e-07 Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 7/165 (4%) Query: 25 TPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEP 84 +P P + G+ D+ V ++ L L +L+ A L + ++ I + L+ Sbjct: 14 SPPAPFETGGNTTGISDVTVSYQVITSLLL-GTLIFCAVLG-NACVVAAIALERSLQNVA 71 Query: 85 HYLLPANILLSDL--AYILLHMLISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAI 142 +YL+ ++ ++DL + ++L M L W LG++ C + CTS+IL AI Sbjct: 72 NYLI-GSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAI 130 Query: 143 VLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVA--CCFPTFLIW 185 L Y A+ P+ Y++ + A ++L WL+ P L W Sbjct: 131 ALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGW 175 >gi|4557865 somatostatin receptor 5 [Homo sapiens] Length = 364 Score = 52.8 bits (125), Expect = 5e-07 Identities = 60/264 (22%), Positives = 113/264 (42%), Gaps = 20/264 (7%) Query: 23 SKTPCMPQAASNTSLGLGDLRV-----PSSMLYWLFLPSS--LLAAATLAVSPLLLVTIL 75 + TP ++ + G GD R PS+ + +P L+ AA L + L++ +L Sbjct: 7 ASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVL 66 Query: 76 RNQRLRQEPH-YLLPANILLSDLAYIL-LHMLISSSSLGGWELGRMACGILTDAVFAACT 133 R +++ + Y+L N+ ++D+ Y+L L L + ++ W G + C ++ Sbjct: 67 RFAKMKTVTNIYIL--NLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQF 124 Query: 134 STILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKWQDAQ 193 +++ T + + YLAV+HPL + A A A W+++ C L+ A Sbjct: 125 TSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVF-----AD 179 Query: 194 LEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIYAEAKTSGIWG 253 ++E G P G V + YT++L F +I C+ I + + +G+ Sbjct: 180 VQEGGTCNASWPE---PVGLWGAVFIIYTAVL-GFFAPLLVICLCYLLIVVKVRAAGVRV 235 Query: 254 QGYSRARGTLLIHSVLITLYVSTG 277 R + VL+ + V G Sbjct: 236 GCVRRRSERKVTRMVLVVVLVFAG 259 >gi|4557265 beta-1-adrenergic receptor [Homo sapiens] Length = 477 Score = 52.8 bits (125), Expect = 5e-07 Identities = 46/195 (23%), Positives = 86/195 (44%), Gaps = 12/195 (6%) Query: 57 SLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSL--GGW 114 +L+ +A + L++V I + RL+ + + ++ +DL LL + ++ + G W Sbjct: 66 ALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFI-MSLASADLVMGLLVVPFGATIVVWGRW 124 Query: 115 ELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWL 174 E G C + T T++I + I L YLA+ P RY S ++ A V +W Sbjct: 125 EYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWA 184 Query: 175 VACCFPTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTY--TSILCVLFLCT 232 ++ +FL L W A+ +E Y P C + Y S + ++ Sbjct: 185 IS-ALVSFLPILMHWWRAESDEARRCYNDPKC------CDFVTNRAYAIASSVVSFYVPL 237 Query: 233 ALIANCFWRIYAEAK 247 ++A + R++ EA+ Sbjct: 238 CIMAFVYLRVFREAQ 252 >gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] Length = 455 Score = 52.4 bits (124), Expect = 6e-07 Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 22/184 (11%) Query: 69 LLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISS--SSLGGWELGRMACGILTD 126 L+++++ ++ L HY + N+ ++DL + S+ LG W GR+ C I Sbjct: 46 LVILSVACHRHLHSVTHYYI-VNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAA 104 Query: 127 AVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW---LVACCFPTFL 183 CT++I+ I + Y+ V +PLRY + ++ A+ +W LV P F Sbjct: 105 VDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF- 163 Query: 184 IWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIY 243 W+ E++ I +PG L S L +L A+I + R+Y Sbjct: 164 ----GWRQPAPEDETICQI-----NEEPGYVLF------SALGSFYLPLAIILVMYCRVY 208 Query: 244 AEAK 247 AK Sbjct: 209 VVAK 212 >gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] Length = 466 Score = 52.4 bits (124), Expect = 6e-07 Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 22/184 (11%) Query: 69 LLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISS--SSLGGWELGRMACGILTD 126 L+++++ ++ L HY + N+ ++DL + S+ LG W GR+ C I Sbjct: 46 LVILSVACHRHLHSVTHYYI-VNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAA 104 Query: 127 AVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW---LVACCFPTFL 183 CT++I+ I + Y+ V +PLRY + ++ A+ +W LV P F Sbjct: 105 VDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF- 163 Query: 184 IWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIY 243 W+ E++ I +PG L S L +L A+I + R+Y Sbjct: 164 ----GWRQPAPEDETICQI-----NEEPGYVLF------SALGSFYLPLAIILVMYCRVY 208 Query: 244 AEAK 247 AK Sbjct: 209 VVAK 212 >gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] Length = 475 Score = 52.4 bits (124), Expect = 6e-07 Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 22/184 (11%) Query: 69 LLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISS--SSLGGWELGRMACGILTD 126 L+++++ ++ L HY + N+ ++DL + S+ LG W GR+ C I Sbjct: 46 LVILSVACHRHLHSVTHYYI-VNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAA 104 Query: 127 AVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW---LVACCFPTFL 183 CT++I+ I + Y+ V +PLRY + ++ A+ +W LV P F Sbjct: 105 VDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF- 163 Query: 184 IWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIY 243 W+ E++ I +PG L S L +L A+I + R+Y Sbjct: 164 ----GWRQPAPEDETICQI-----NEEPGYVLF------SALGSFYLPLAIILVMYCRVY 208 Query: 244 AEAK 247 AK Sbjct: 209 VVAK 212 >gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] Length = 429 Score = 52.4 bits (124), Expect = 6e-07 Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 22/184 (11%) Query: 69 LLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISS--SSLGGWELGRMACGILTD 126 L+++++ ++ L HY + N+ ++DL + S+ LG W GR+ C I Sbjct: 46 LVILSVACHRHLHSVTHYYI-VNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAA 104 Query: 127 AVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW---LVACCFPTFL 183 CT++I+ I + Y+ V +PLRY + ++ A+ +W LV P F Sbjct: 105 VDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF- 163 Query: 184 IWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLCTALIANCFWRIY 243 W+ E++ I +PG L S L +L A+I + R+Y Sbjct: 164 ----GWRQPAPEDETICQI-----NEEPGYVLF------SALGSFYLPLAIILVMYCRVY 208 Query: 244 AEAK 247 AK Sbjct: 209 VVAK 212 >gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sapiens] Length = 366 Score = 52.4 bits (124), Expect = 6e-07 Identities = 49/211 (23%), Positives = 88/211 (41%), Gaps = 24/211 (11%) Query: 43 RVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILL 102 R+PS +L L L S LA T ++ L++ I+ ++L +YL+ ++ ++D +L Sbjct: 19 RMPSKILVSLTL--SGLALMTTTINSLVIAAIIVTRKLHHPANYLI-CSLAVTDFLVAVL 75 Query: 103 HMLISSSSL--GGWELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFM 160 M S + W +G++ C I CT +IL +AI L Y A+ + Y Sbjct: 76 VMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKR 135 Query: 161 SHGAAWKAVALIWLVACCF---PTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLV 217 + A + ++W+++ P F W+ I + Sbjct: 136 TPKHAGIMITIVWIISVFISMPPLF------WRHQGTSRDDECIIKHDH----------I 179 Query: 218 IVTYTSILCVLFLCTALIANCFWRIYAEAKT 248 + T S ++ ALI +++IY AKT Sbjct: 180 VSTIYSTFGAFYIPLALILILYYKIYRAAKT 210 >gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] Length = 384 Score = 52.4 bits (124), Expect = 6e-07 Identities = 60/286 (20%), Positives = 120/286 (41%), Gaps = 28/286 (9%) Query: 41 DLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDL--A 98 D +P +M++ L L + ++ + L++ IL+ + +R + L+ N+ SDL A Sbjct: 32 DCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILI-VNLSFSDLLVA 90 Query: 99 YILLHMLISSSSLGGWELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLS 158 + L + + W G C + + T +I S I + + +I+P + Sbjct: 91 IMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRP 150 Query: 159 FMSHGAAWKAVALIWLVACCFPT-FLIWL----SKWQDAQLEEQGASYI----LPPSMGT 209 H A+ +A+IW++A FLI+ +Q+ L+ Y+ P Sbjct: 151 NNRH--AYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHR 208 Query: 210 QPGCGLLVIVTYTSILCVLFLCTALIANCFWRIYAEAKTSG----IWGQGYSRARGTLLI 265 LL+++ Y LC +F+ C+++IY K R+ T I Sbjct: 209 LSYTTLLLVLQYFGPLCFIFI-------CYFKIYIRLKRRNNMMDKMRDNKYRSSETKRI 261 Query: 266 HSVLITLYVSTGVVFSLDMVLTRYHHIDSGTHTWLLAANSEVLMML 311 + +L+++ V+ V + + LT ++ + H + N +L +L Sbjct: 262 NIMLLSIVVAFAVCW---LPLTIFNTVFDWNHQIIATCNHNLLFLL 304 >gi|16876435 G protein-coupled receptor 101 [Homo sapiens] Length = 508 Score = 52.4 bits (124), Expect = 6e-07 Identities = 54/216 (25%), Positives = 96/216 (44%), Gaps = 17/216 (7%) Query: 23 SKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLRQ 82 S CMP + SL G +R S + +FL +S + LA LV + Q L+ Sbjct: 14 SSHTCMPLSKMPISLAHGIIR---STVLVIFLAASFVGNIVLA-----LVLQRKPQLLQV 65 Query: 83 EPHYLLPANILLSDLAYILL--HMLISSSSLGGWELGRMACGILTDAVFAACTSTILSFT 140 ++ N+L++DL I L ++++S W L C L +++ + Sbjct: 66 TNRFIF--NLLVTDLLQISLVAPWVVATSVPLFWPLNSHFCTALVSLTHLFAFASVNTIV 123 Query: 141 AIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTFLIWLSKWQDAQLEEQGAS 200 + + YL++IHPL Y S M+ + + W+VA T ++ W A +E+ A Sbjct: 124 VVSVDRYLSIIHPLSYPSKMTQRRGYLLLYGTWIVAILQSTPPLY--GWGQAAFDERNA- 180 Query: 201 YILPPSMGTQPGCGLLVIVTYTSI-LCVLFLCTALI 235 + G P +L +V++ I L V+ C +++ Sbjct: 181 -LCSMIWGASPSYTILSVVSFIVIPLIVMIACYSVV 215 >gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens] Length = 590 Score = 52.0 bits (123), Expect = 8e-07 Identities = 39/196 (19%), Positives = 87/196 (44%), Gaps = 15/196 (7%) Query: 56 SSLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDL--AYILLHMLISSSSLGG 113 + +LA T+ + L++V+ N++L+ +Y L ++ +DL I +++ + + Sbjct: 75 TGILALVTIIGNILVIVSFKVNKQLKTVNNYFL-LSLACADLIIGVISMNLFTTYIIMNR 133 Query: 114 WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW 173 W LG +AC + + A +++++ I Y ++ PL Y + + A + L W Sbjct: 134 WALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAW 193 Query: 174 LVACCF--PTFLIWLSKWQDAQLEEQGASYILPPSMGTQPGCGLLVIVTYTSILCVLFLC 231 +++ P L W + + G +I S T +T+ + + ++ Sbjct: 194 VISFVLWAPAILFW-QYFVGKRTVPPGECFIQFLSEPT---------ITFGTAIAAFYMP 243 Query: 232 TALIANCFWRIYAEAK 247 ++ +WRIY E + Sbjct: 244 VTIMTILYWRIYKETE 259 >gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] Length = 432 Score = 50.8 bits (120), Expect = 2e-06 Identities = 34/140 (24%), Positives = 66/140 (47%), Gaps = 6/140 (4%) Query: 57 SLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHM-LISSSSL--GG 113 +L+ T+A + L+++++ ++LRQ +YL+ ++ L+DL+ + M +S + L G Sbjct: 89 TLITLLTIAGNCLVVISVCFVKKLRQPSNYLI-VSLALADLSVAVAVMPFVSVTDLIGGK 147 Query: 114 WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW 173 W G C + CT++I++ I + YL + PL Y + K + +W Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207 Query: 174 LVAC--CFPTFLIWLSKWQD 191 L++ P W D Sbjct: 208 LLSASITLPPLFGWAQNVND 227 >gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] Length = 479 Score = 50.8 bits (120), Expect = 2e-06 Identities = 34/140 (24%), Positives = 66/140 (47%), Gaps = 6/140 (4%) Query: 57 SLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHM-LISSSSL--GG 113 +L+ T+A + L+++++ ++LRQ +YL+ ++ L+DL+ + M +S + L G Sbjct: 89 TLITLLTIAGNCLVVISVCFVKKLRQPSNYLI-VSLALADLSVAVAVMPFVSVTDLIGGK 147 Query: 114 WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW 173 W G C + CT++I++ I + YL + PL Y + K + +W Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207 Query: 174 LVAC--CFPTFLIWLSKWQD 191 L++ P W D Sbjct: 208 LLSASITLPPLFGWAQNVND 227 >gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] Length = 445 Score = 50.8 bits (120), Expect = 2e-06 Identities = 34/140 (24%), Positives = 66/140 (47%), Gaps = 6/140 (4%) Query: 57 SLLAAATLAVSPLLLVTILRNQRLRQEPHYLLPANILLSDLAYILLHM-LISSSSL--GG 113 +L+ T+A + L+++++ ++LRQ +YL+ ++ L+DL+ + M +S + L G Sbjct: 89 TLITLLTIAGNCLVVISVCFVKKLRQPSNYLI-VSLALADLSVAVAVMPFVSVTDLIGGK 147 Query: 114 WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIW 173 W G C + CT++I++ I + YL + PL Y + K + +W Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207 Query: 174 LVAC--CFPTFLIWLSKWQD 191 L++ P W D Sbjct: 208 LLSASITLPPLFGWAQNVND 227 >gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo sapiens] Length = 458 Score = 50.4 bits (119), Expect = 2e-06 Identities = 39/170 (22%), Positives = 77/170 (45%), Gaps = 6/170 (3%) Query: 10 VGTTAWPALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPL 69 +G W I +S + NTS G G + P + W L ++ T+ + L Sbjct: 16 IGLLVWQCDIS-VSPVAAIVTDIFNTSDG-GRFKFPDGVQNWPALSIVIIIIMTIGGNIL 73 Query: 70 LLVTILRNQRLRQEPHYLLPANILLSDLAYILLHMLISSSSL---GGWELGRMACGILTD 126 +++ + ++L +Y L ++ ++D+ LL M +S ++ W L R C + Sbjct: 74 VIMAVSMEKKLHNATNYFL-MSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWIS 132 Query: 127 AVFAACTSTILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVA 176 T++I+ AI L Y+A+ +P+ + F S A +A++W ++ Sbjct: 133 LDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAIS 182 >gi|57165371 G protein-coupled receptor 61 [Homo sapiens] Length = 451 Score = 49.3 bits (116), Expect = 5e-06 Identities = 59/231 (25%), Positives = 98/231 (42%), Gaps = 34/231 (14%) Query: 22 ISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILRNQRLR 81 + +TP A+ +GL D+ S L+++ L A AV + I + LR Sbjct: 19 VPQTPGPSTASGVPEVGLRDVASESVALFFMLLLDLTAVAGNAAV----MAVIAKTPALR 74 Query: 82 QEPHYLLPANILLSDLAYILLHM---LISSSSLGGWEL-GRMACGILTDAVFAACTSTIL 137 + ++ ++ L DL L M ++SSS+L L G +AC + + IL Sbjct: 75 K---FVFVFHLCLVDLLAALTLMPLAMLSSSALFDHALFGEVACRLYLFLSVCFVSLAIL 131 Query: 138 SFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCFPTF-LIWLSKWQDAQLEE 196 S +AI + Y V+HP+RY M+ G + +W+ A + ++ W E Sbjct: 132 SVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVSW------E 185 Query: 197 QGASYILPPSMGTQPGCGL---------LVIVTYTSILCVLFLCTALIANC 238 +GA PS+ PGC L L +V + + +L L L+ C Sbjct: 186 EGA-----PSV--PPGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYC 229 >gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens] Length = 328 Score = 48.9 bits (115), Expect = 7e-06 Identities = 55/196 (28%), Positives = 84/196 (42%), Gaps = 17/196 (8%) Query: 52 LFLPS--SLLAAATLAVSPLLLVTILRNQR-LRQEPHYLLPANILLSDLAYIL-LHMLIS 107 L LP S + AA L ++ ++ I ++R L + Y L N+ L+DL Y L +LI Sbjct: 27 LLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTL--NLALADLLYACSLPLLIY 84 Query: 108 SSSLGG-WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLR-YLSFMSHGAA 165 + + G W G AC ++ +A +IL T I YL + HPL + AA Sbjct: 85 NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAA 144 Query: 166 WKAVALIWLVAC--CFPTFLIWLSKWQDAQLEEQGASYIL-PPSMGT--QPGCGLLVIVT 220 W +WL C PT + + Q + Y L PP++ T P L ++ Sbjct: 145 WLVCVAVWLAVTTQCLPTAIFAATGIQ----RNRTVCYDLSPPALATHYMPYGMALTVIG 200 Query: 221 YTSILCVLFLCTALIA 236 + L C L+A Sbjct: 201 FLLPFAALLACYCLLA 216 >gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens] Length = 328 Score = 48.9 bits (115), Expect = 7e-06 Identities = 55/196 (28%), Positives = 84/196 (42%), Gaps = 17/196 (8%) Query: 52 LFLPS--SLLAAATLAVSPLLLVTILRNQR-LRQEPHYLLPANILLSDLAYIL-LHMLIS 107 L LP S + AA L ++ ++ I ++R L + Y L N+ L+DL Y L +LI Sbjct: 27 LLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTL--NLALADLLYACSLPLLIY 84 Query: 108 SSSLGG-WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLR-YLSFMSHGAA 165 + + G W G AC ++ +A +IL T I YL + HPL + AA Sbjct: 85 NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAA 144 Query: 166 WKAVALIWLVAC--CFPTFLIWLSKWQDAQLEEQGASYIL-PPSMGT--QPGCGLLVIVT 220 W +WL C PT + + Q + Y L PP++ T P L ++ Sbjct: 145 WLVCVAVWLAVTTQCLPTAIFAATGIQ----RNRTVCYDLSPPALATHYMPYGMALTVIG 200 Query: 221 YTSILCVLFLCTALIA 236 + L C L+A Sbjct: 201 FLLPFAALLACYCLLA 216 >gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens] Length = 328 Score = 48.9 bits (115), Expect = 7e-06 Identities = 55/196 (28%), Positives = 84/196 (42%), Gaps = 17/196 (8%) Query: 52 LFLPS--SLLAAATLAVSPLLLVTILRNQR-LRQEPHYLLPANILLSDLAYIL-LHMLIS 107 L LP S + AA L ++ ++ I ++R L + Y L N+ L+DL Y L +LI Sbjct: 27 LLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTL--NLALADLLYACSLPLLIY 84 Query: 108 SSSLGG-WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLR-YLSFMSHGAA 165 + + G W G AC ++ +A +IL T I YL + HPL + AA Sbjct: 85 NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAA 144 Query: 166 WKAVALIWLVAC--CFPTFLIWLSKWQDAQLEEQGASYIL-PPSMGT--QPGCGLLVIVT 220 W +WL C PT + + Q + Y L PP++ T P L ++ Sbjct: 145 WLVCVAVWLAVTTQCLPTAIFAATGIQ----RNRTVCYDLSPPALATHYMPYGMALTVIG 200 Query: 221 YTSILCVLFLCTALIA 236 + L C L+A Sbjct: 201 FLLPFAALLACYCLLA 216 >gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens] Length = 328 Score = 48.9 bits (115), Expect = 7e-06 Identities = 55/196 (28%), Positives = 84/196 (42%), Gaps = 17/196 (8%) Query: 52 LFLPS--SLLAAATLAVSPLLLVTILRNQR-LRQEPHYLLPANILLSDLAYIL-LHMLIS 107 L LP S + AA L ++ ++ I ++R L + Y L N+ L+DL Y L +LI Sbjct: 27 LLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTL--NLALADLLYACSLPLLIY 84 Query: 108 SSSLGG-WELGRMACGILTDAVFAACTSTILSFTAIVLHTYLAVIHPLR-YLSFMSHGAA 165 + + G W G AC ++ +A +IL T I YL + HPL + AA Sbjct: 85 NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAA 144 Query: 166 WKAVALIWLVAC--CFPTFLIWLSKWQDAQLEEQGASYIL-PPSMGT--QPGCGLLVIVT 220 W +WL C PT + + Q + Y L PP++ T P L ++ Sbjct: 145 WLVCVAVWLAVTTQCLPTAIFAATGIQ----RNRTVCYDLSPPALATHYMPYGMALTVIG 200 Query: 221 YTSILCVLFLCTALIA 236 + L C L+A Sbjct: 201 FLLPFAALLACYCLLA 216 >gi|15150803 opsin 4 isoform 1 [Homo sapiens] Length = 478 Score = 48.5 bits (114), Expect = 9e-06 Identities = 58/251 (23%), Positives = 98/251 (39%), Gaps = 17/251 (6%) Query: 17 ALIQLISKTPCMPQAASNTSLGLGDLRVPSSMLYWLFLPSSLLAAATLAVSPLLLVTILR 76 +L +L S +P P + + L + VP Y L L+ + + ++ T R Sbjct: 38 SLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCR 97 Query: 77 NQRLRQEPHYLLPANILLSD--LAYILLHMLISSSSLGGWELGRMACGILTDAVFAACTS 134 ++ LR P + N+ +SD +++ + +SS W G C S Sbjct: 98 SRSLRT-PANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGIS 156 Query: 135 TILSFTAIVLHTYLAVIHPLRYLSFMSHGAAWKAVALIWLVACCF--PTFLIWLSKWQDA 192 ++++ TAI L YL + PL S A + +WL A + P F W + + Sbjct: 157 SMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEG 216 Query: 193 QLEEQGASYILPPSMGTQPGCGLLVIVTYTSILC--VLFLCTALIANCFWRIYAEAKTSG 250 L Y M P + YT +LC V FL +I C+ I+ + +G Sbjct: 217 LLTSCSWDY-----MSFTP-----AVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETG 266 Query: 251 IWGQGYSRARG 261 Q + +G Sbjct: 267 RALQTFGACKG 277 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.328 0.138 0.444 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,804,346 Number of Sequences: 37866 Number of extensions: 525382 Number of successful extensions: 2223 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 188 Number of HSP's successfully gapped in prelim test: 266 Number of HSP's that attempted gapping in prelim test: 1920 Number of HSP's gapped (non-prelim): 488 length of query: 347 length of database: 18,247,518 effective HSP length: 103 effective length of query: 244 effective length of database: 14,347,320 effective search space: 3500746080 effective search space used: 3500746080 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.8 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.