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Search of human proteins with 46240864
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46240864 sperm associated antigen 17 [Homo sapiens]
(2223 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46240864 sperm associated antigen 17 [Homo sapiens] 4451 0.0
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 57 2e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 56 4e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 55 1e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 54 1e-06
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap... 54 1e-06
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 54 2e-06
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 53 4e-06
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 53 4e-06
gi|88759339 aster-associated protein [Homo sapiens] 52 6e-06
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 52 8e-06
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 52 8e-06
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 50 2e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 3e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 3e-05
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 50 3e-05
gi|104526627 triadin [Homo sapiens] 50 3e-05
gi|148746195 trichohyalin [Homo sapiens] 49 4e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 49 5e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 49 7e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 48 9e-05
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 48 9e-05
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 48 9e-05
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 48 1e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 48 1e-04
gi|150170670 piccolo isoform 2 [Homo sapiens] 47 2e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 47 2e-04
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 47 2e-04
gi|6005757 chromatin-specific transcription elongation factor la... 47 2e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 47 3e-04
>gi|46240864 sperm associated antigen 17 [Homo sapiens]
Length = 2223
Score = 4451 bits (11544), Expect = 0.0
Identities = 2223/2223 (100%), Positives = 2223/2223 (100%)
Query: 1 MAPKKEKGGTVNTSSKIWEPSLIAAQFNQNDWQASIAFVVGNQIEDDLLIQALTVAVQVP 60
MAPKKEKGGTVNTSSKIWEPSLIAAQFNQNDWQASIAFVVGNQIEDDLLIQALTVAVQVP
Sbjct: 1 MAPKKEKGGTVNTSSKIWEPSLIAAQFNQNDWQASIAFVVGNQIEDDLLIQALTVAVQVP 60
Query: 61 QRKLFSMVSWQDILQQINEINTLVGSASSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKL 120
QRKLFSMVSWQDILQQINEINTLVGSASSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKL
Sbjct: 61 QRKLFSMVSWQDILQQINEINTLVGSASSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKL 120
Query: 121 TLPLIGKLLKFQLLQIKFKDQQRRENEKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKG 180
TLPLIGKLLKFQLLQIKFKDQQRRENEKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKG
Sbjct: 121 TLPLIGKLLKFQLLQIKFKDQQRRENEKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKG 180
Query: 181 KGKDQPEANAPVKKTTQLKRRGEDDHTNRYIDDEPDDGAQHYIIVVGFNNPQLLAIMAEL 240
KGKDQPEANAPVKKTTQLKRRGEDDHTNRYIDDEPDDGAQHYIIVVGFNNPQLLAIMAEL
Sbjct: 181 KGKDQPEANAPVKKTTQLKRRGEDDHTNRYIDDEPDDGAQHYIIVVGFNNPQLLAIMAEL 240
Query: 241 GIPITSVIKISSENYEPLQTHLAAVNQQQEVLLQSEDLEAEKLKKENAIKELKTFWKYLE 300
GIPITSVIKISSENYEPLQTHLAAVNQQQEVLLQSEDLEAEKLKKENAIKELKTFWKYLE
Sbjct: 241 GIPITSVIKISSENYEPLQTHLAAVNQQQEVLLQSEDLEAEKLKKENAIKELKTFWKYLE 300
Query: 301 PVLNNEKPETNLFDVARLEYMVKAADFPSDWSDGEMMLKLGTDIFENIACLMYDILDWKR 360
PVLNNEKPETNLFDVARLEYMVKAADFPSDWSDGEMMLKLGTDIFENIACLMYDILDWKR
Sbjct: 301 PVLNNEKPETNLFDVARLEYMVKAADFPSDWSDGEMMLKLGTDIFENIACLMYDILDWKR 360
Query: 361 QHQHYLESMQLINVPQVVNEKPVLEAMPTSEAPQPAVPAPGKKKAQYEEPQAPPPVTSVI 420
QHQHYLESMQLINVPQVVNEKPVLEAMPTSEAPQPAVPAPGKKKAQYEEPQAPPPVTSVI
Sbjct: 361 QHQHYLESMQLINVPQVVNEKPVLEAMPTSEAPQPAVPAPGKKKAQYEEPQAPPPVTSVI 420
Query: 421 TTEVDMRYYNYLLNPIREEFISVPLILHCMLEQVVATEEDLVPPSLREPSPRADGLDHRI 480
TTEVDMRYYNYLLNPIREEFISVPLILHCMLEQVVATEEDLVPPSLREPSPRADGLDHRI
Sbjct: 421 TTEVDMRYYNYLLNPIREEFISVPLILHCMLEQVVATEEDLVPPSLREPSPRADGLDHRI 480
Query: 481 AAHIVSLLPSLCLSEREKKNLHDIFLSEEENESKAVPKGPLLLNYHDAHAHKKYALQDQK 540
AAHIVSLLPSLCLSEREKKNLHDIFLSEEENESKAVPKGPLLLNYHDAHAHKKYALQDQK
Sbjct: 481 AAHIVSLLPSLCLSEREKKNLHDIFLSEEENESKAVPKGPLLLNYHDAHAHKKYALQDQK 540
Query: 541 NFDPVQIEQEMQSKLPLWEFLQFPLPPPWNNTKRLATIHELMHFCTSDVLSWNEVERAFK 600
NFDPVQIEQEMQSKLPLWEFLQFPLPPPWNNTKRLATIHELMHFCTSDVLSWNEVERAFK
Sbjct: 541 NFDPVQIEQEMQSKLPLWEFLQFPLPPPWNNTKRLATIHELMHFCTSDVLSWNEVERAFK 600
Query: 601 VFTFESLKLSEVDEKGKLKPSGMMCGSDSEMFNIPWDNPARFAKQIRQQYVMKMNTQEAK 660
VFTFESLKLSEVDEKGKLKPSGMMCGSDSEMFNIPWDNPARFAKQIRQQYVMKMNTQEAK
Sbjct: 601 VFTFESLKLSEVDEKGKLKPSGMMCGSDSEMFNIPWDNPARFAKQIRQQYVMKMNTQEAK 660
Query: 661 QKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLKLSVPDNRQL 720
QKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLKLSVPDNRQL
Sbjct: 661 QKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLKLSVPDNRQL 720
Query: 721 LEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLM 780
LEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLM
Sbjct: 721 LEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLM 780
Query: 781 DWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIAL 840
DWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIAL
Sbjct: 781 DWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIAL 840
Query: 841 HSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKI 900
HSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKI
Sbjct: 841 HSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKI 900
Query: 901 FSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAE 960
FSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAE
Sbjct: 901 FSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAE 960
Query: 961 KKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFH 1020
KKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFH
Sbjct: 961 KKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFH 1020
Query: 1021 GYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKE 1080
GYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKE
Sbjct: 1021 GYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKE 1080
Query: 1081 IVKKEEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSN 1140
IVKKEEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSN
Sbjct: 1081 IVKKEEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSN 1140
Query: 1141 GMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEE 1200
GMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEE
Sbjct: 1141 GMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEE 1200
Query: 1201 EKKEEEVEPEPVLQETLDVPTFQSLNVSCPSGLLLTFIGQESTGQYVIDEEPTWDIMVRQ 1260
EKKEEEVEPEPVLQETLDVPTFQSLNVSCPSGLLLTFIGQESTGQYVIDEEPTWDIMVRQ
Sbjct: 1201 EKKEEEVEPEPVLQETLDVPTFQSLNVSCPSGLLLTFIGQESTGQYVIDEEPTWDIMVRQ 1260
Query: 1261 SYPQRVKHYEFYKTVMPPAEQEASRVITSQGTVVKYMLDGSTQILFADGAVSRSPNSGLI 1320
SYPQRVKHYEFYKTVMPPAEQEASRVITSQGTVVKYMLDGSTQILFADGAVSRSPNSGLI
Sbjct: 1261 SYPQRVKHYEFYKTVMPPAEQEASRVITSQGTVVKYMLDGSTQILFADGAVSRSPNSGLI 1320
Query: 1321 CPPSEMPATPHSGDLMDSISQQKSETIPSEITNTKKGKSHKSQSSMAHKGEIHDPPPEAV 1380
CPPSEMPATPHSGDLMDSISQQKSETIPSEITNTKKGKSHKSQSSMAHKGEIHDPPPEAV
Sbjct: 1321 CPPSEMPATPHSGDLMDSISQQKSETIPSEITNTKKGKSHKSQSSMAHKGEIHDPPPEAV 1380
Query: 1381 QTVTPVEVHIGTWFTTTPEGNRIGTKGLERIADLTPLLSFQATDPVNGTVMTTREDKVVI 1440
QTVTPVEVHIGTWFTTTPEGNRIGTKGLERIADLTPLLSFQATDPVNGTVMTTREDKVVI
Sbjct: 1381 QTVTPVEVHIGTWFTTTPEGNRIGTKGLERIADLTPLLSFQATDPVNGTVMTTREDKVVI 1440
Query: 1441 VERKDGTRIVDHADGTRITTFYQVYEDQIILPDDQETTEGPRTVTRQVKCMRVESSRYAT 1500
VERKDGTRIVDHADGTRITTFYQVYEDQIILPDDQETTEGPRTVTRQVKCMRVESSRYAT
Sbjct: 1441 VERKDGTRIVDHADGTRITTFYQVYEDQIILPDDQETTEGPRTVTRQVKCMRVESSRYAT 1500
Query: 1501 VIANCEDSSCCATFGDGTTIIAKPQGTYQVLPPNTGSLYIDKDCSAVYCHESSSNIYYPF 1560
VIANCEDSSCCATFGDGTTIIAKPQGTYQVLPPNTGSLYIDKDCSAVYCHESSSNIYYPF
Sbjct: 1501 VIANCEDSSCCATFGDGTTIIAKPQGTYQVLPPNTGSLYIDKDCSAVYCHESSSNIYYPF 1560
Query: 1561 QKREQLRAGRYIMRHTSEVICEVLDPEGNTFQVMADGSISTILPEKKLEDDLNEKTEGYD 1620
QKREQLRAGRYIMRHTSEVICEVLDPEGNTFQVMADGSISTILPEKKLEDDLNEKTEGYD
Sbjct: 1561 QKREQLRAGRYIMRHTSEVICEVLDPEGNTFQVMADGSISTILPEKKLEDDLNEKTEGYD 1620
Query: 1621 SLSSMHLEKNHQQIYGEHVPRFFVMYADGSGMELLRDSDIEEYLSLAYKESNTVVLQEPV 1680
SLSSMHLEKNHQQIYGEHVPRFFVMYADGSGMELLRDSDIEEYLSLAYKESNTVVLQEPV
Sbjct: 1621 SLSSMHLEKNHQQIYGEHVPRFFVMYADGSGMELLRDSDIEEYLSLAYKESNTVVLQEPV 1680
Query: 1681 QEQPGTLTITVLRPFHEASPWQVKKEDTIVPPNLRSRSWETFPSVEKKTPGPPFGTQIWK 1740
QEQPGTLTITVLRPFHEASPWQVKKEDTIVPPNLRSRSWETFPSVEKKTPGPPFGTQIWK
Sbjct: 1681 QEQPGTLTITVLRPFHEASPWQVKKEDTIVPPNLRSRSWETFPSVEKKTPGPPFGTQIWK 1740
Query: 1741 GLCIESKQLVSAPGAILKSPSVLQMRQFIQHEVIKNEVKLRLQVSLKDYINYILKKEDEL 1800
GLCIESKQLVSAPGAILKSPSVLQMRQFIQHEVIKNEVKLRLQVSLKDYINYILKKEDEL
Sbjct: 1741 GLCIESKQLVSAPGAILKSPSVLQMRQFIQHEVIKNEVKLRLQVSLKDYINYILKKEDEL 1800
Query: 1801 QEMMVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSLATPPKCP 1860
QEMMVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSLATPPKCP
Sbjct: 1801 QEMMVKDSRTEEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSLATPPKCP 1860
Query: 1861 PDTFGKDFFEKTWRHTASSKRWKEKIDKTRKEIETTQNYLMDIKNRIIPPFFKSELNQLY 1920
PDTFGKDFFEKTWRHTASSKRWKEKIDKTRKEIETTQNYLMDIKNRIIPPFFKSELNQLY
Sbjct: 1861 PDTFGKDFFEKTWRHTASSKRWKEKIDKTRKEIETTQNYLMDIKNRIIPPFFKSELNQLY 1920
Query: 1921 QSQYNHLDSLSKKLPSFTKKNEDANETAVQDTSDLNLDFKPHKVSEQKSSSVPSLPKPEI 1980
QSQYNHLDSLSKKLPSFTKKNEDANETAVQDTSDLNLDFKPHKVSEQKSSSVPSLPKPEI
Sbjct: 1921 QSQYNHLDSLSKKLPSFTKKNEDANETAVQDTSDLNLDFKPHKVSEQKSSSVPSLPKPEI 1980
Query: 1981 SADKKDFTAQNQTENLTKSPEEAESYEPVKIPTQSLLQDVAGQTRKEKVKLPHYLLSSKP 2040
SADKKDFTAQNQTENLTKSPEEAESYEPVKIPTQSLLQDVAGQTRKEKVKLPHYLLSSKP
Sbjct: 1981 SADKKDFTAQNQTENLTKSPEEAESYEPVKIPTQSLLQDVAGQTRKEKVKLPHYLLSSKP 2040
Query: 2041 KSQPLAKVQDSVGGKVNTSSVASAAINNAKSSLFGFHLLPSSVKFGVLKEGHTYATVVKL 2100
KSQPLAKVQDSVGGKVNTSSVASAAINNAKSSLFGFHLLPSSVKFGVLKEGHTYATVVKL
Sbjct: 2041 KSQPLAKVQDSVGGKVNTSSVASAAINNAKSSLFGFHLLPSSVKFGVLKEGHTYATVVKL 2100
Query: 2101 KNVGVDFCRFKVKQPPPSTGLKVTYKPGPVAAGMQTELNIELFATAVGEDGAKGSAHISH 2160
KNVGVDFCRFKVKQPPPSTGLKVTYKPGPVAAGMQTELNIELFATAVGEDGAKGSAHISH
Sbjct: 2101 KNVGVDFCRFKVKQPPPSTGLKVTYKPGPVAAGMQTELNIELFATAVGEDGAKGSAHISH 2160
Query: 2161 NIEIMTEHEVLFLPVEATVLTSSNYDKRPKDFPQGKENPMVQRTSTIYSSTLGVFMSRKV 2220
NIEIMTEHEVLFLPVEATVLTSSNYDKRPKDFPQGKENPMVQRTSTIYSSTLGVFMSRKV
Sbjct: 2161 NIEIMTEHEVLFLPVEATVLTSSNYDKRPKDFPQGKENPMVQRTSTIYSSTLGVFMSRKV 2220
Query: 2221 SPH 2223
SPH
Sbjct: 2221 SPH 2223
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 57.4 bits (137), Expect = 2e-07
Identities = 85/393 (21%), Positives = 173/393 (44%), Gaps = 56/393 (14%)
Query: 652 MKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLK 711
++ +E K + +++++ TL + L S+ E +E S + + N+M+
Sbjct: 890 LEKTCKELKHQLQVQMEN-TLKEQKELKKSL---EKEKEASHQLKLELNSMQE------- 938
Query: 712 LSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDI 771
QL++ ++ +K + E Q NE+K + K +K+ + + E + +
Sbjct: 939 -------QLIQAQNTLKQNEKEEQQLQGNINELKQSSEQK----KKQIEALQGELKIAVL 987
Query: 772 KKTQQRSLMDWSFT--------EHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFH 823
+KT+ + + T E K VL +++ + ++ + S ++ +++ LL
Sbjct: 988 QKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLAT-- 1045
Query: 824 NPMNRQRLHC--EYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTR 881
RQ L E ++A + RN + K IQ+ T + + Q+S E+ ++ R
Sbjct: 1046 ----RQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQER 1101
Query: 882 A----ELELKSSANAK--LTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEG 935
+++ + S K + SK+ I+E K + T+++++ K + E I I
Sbjct: 1102 CKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEIT-- 1159
Query: 936 SLKAWKEEQHRLAEEERLREEKKAE--KKGKEAGKKKG---KDNAEKEDSRSLKKKSPYK 990
+LK K+ L +++L + KA+ K E K+ KD +KE+ LKK+ K
Sbjct: 1160 NLKDAKQ----LLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEE-LKKEFIEK 1214
Query: 991 EKSKEEQVKIQEVTEESPHQPEPKITYPFHGYN 1023
E ++K +EV + + E K+T N
Sbjct: 1215 EAKLHSEIKEKEVGMKKHEENEAKLTMQITALN 1247
Score = 36.2 bits (82), Expect = 0.37
Identities = 88/440 (20%), Positives = 177/440 (40%), Gaps = 57/440 (12%)
Query: 637 DNPARFAKQIRQQYVMKMNTQEAKQKADIKIKD-----RTLFVDQNLSMSVQDNESNREP 691
++ A K++ Q + N +++ K+KD ++ + ++S +E + P
Sbjct: 221 EDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGP 280
Query: 692 SDPSQCDANNMKHSDLNNLKLSVPDNRQLLEQ--ESIMKAQPQHESLEQTTNNEIKDDAV 749
+ + + +L LK SV + Q + E+++K + + LE+ N E
Sbjct: 281 QEVA------VYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKN 334
Query: 750 TKADSHEKKPKKMMVEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDS 809
+A H+K D+ Q +S + S T + V L EA ++ + S
Sbjct: 335 IQATLHQK------------DLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELS 382
Query: 810 YYHTQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQ 869
T+ L F + +QR E + L S + +L +K ++ T+ +
Sbjct: 383 EVETKYQHLKAEF-KQLQQQREEKEQHGLQLQSEIN-----QLHSKLLE---TERQLGEA 433
Query: 870 ESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQ-EKEKEKEK 928
++ E+ + +L K A L K+ ++E K + TE+ Q +K K++ +
Sbjct: 434 HGRLKEQRQLSSEKLMDKEQQVADL--QLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQ 491
Query: 929 IPFILEGSLKA-WKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDN-----AEKED--- 979
L+ S A +E Q+ L + R +K + + EA +K K+N E+ED
Sbjct: 492 EQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYA 551
Query: 980 -----SRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGS 1034
+ +EK+ Q ++ ++TE+ +Q E H N+ Q+
Sbjct: 552 KIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSES------HKQAQENLHDQVQEQ 605
Query: 1035 NYYLYPSDGGQIEVEKTMFE 1054
+L + + +E ++ E
Sbjct: 606 KAHLRAAQDRVLSLETSVNE 625
Score = 31.6 bits (70), Expect = 9.1
Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 7/110 (6%)
Query: 1913 KSELNQLYQSQYNHLDSLSKKLPSFTKKNEDANETAVQ----DTSDLNLDFKPHKVSEQK 1968
KS +N+L Q ++L KK +TK E NE +V + D ++ +
Sbjct: 294 KSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRL 353
Query: 1969 SSSVPSLPKPEISADKKDFTAQNQTENLTKSPEEAESYEPVKIPTQSLLQ 2018
S+S SL + + +K Q E L+ E Y+ +K + L Q
Sbjct: 354 SASETSLHRIHVELSEKGEATQKLKEELS---EVETKYQHLKAEFKQLQQ 400
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 55.8 bits (133), Expect = 4e-07
Identities = 60/294 (20%), Positives = 133/294 (45%), Gaps = 22/294 (7%)
Query: 723 QESIMKAQPQHESL-EQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLMD 781
QE K + Q E + EQ +++ + + + ++ ++MM E + +K ++ M
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE----EKMRRLEEMM 372
Query: 782 WSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALH 841
W K + + ++ ++ H+Q + + Q+ + RQ + W
Sbjct: 373 WE-----KEEKIRELEEKMHEQEKIREQEEKRQEEEKI---REQEKRQEQEAKMWR---- 420
Query: 842 SNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIF 901
R E + + + +EE I+++ K+ E+ R E E K+ +I+
Sbjct: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIW 478
Query: 902 SIKES--KSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKA 959
KE + K + E +++EK ++ I E K W++E+ +EE++RE+++
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Query: 960 EKKGKEAGKKKGKDNAEKEDS-RSLKKKSPYKEKSKEEQVKIQEVTEESPHQPE 1012
++ +E +++ + E+E+ + +K +EK +E++ KI+E E+ Q E
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
Score = 40.4 bits (93), Expect = 0.020
Identities = 41/181 (22%), Positives = 84/181 (46%), Gaps = 10/181 (5%)
Query: 840 LHSNVGFRNYLELVAKSIQDWITKEEAIY-QESKMNEKIIRTRAELELKSSANAKLTSAS 898
+H R E V + + +EE I QE KM + + R + E K+
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
Query: 899 KIFSIKESKSNKGISKTEISDQEK-----EKEKEKIPFILEGSLKAWKEEQHRLAEEERL 953
++ +E K G + ++ +QEK EK +E+ I E K ++E+ +EE++
Sbjct: 544 EMMQEQEEKM--GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI 601
Query: 954 REEKKAEKKGKEAGKKKGKDNAEKED--SRSLKKKSPYKEKSKEEQVKIQEVTEESPHQP 1011
RE+++ ++ +E ++ + E+E+ +K +EK E++V++++ E+
Sbjct: 602 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Query: 1012 E 1012
E
Sbjct: 662 E 662
Score = 35.4 bits (80), Expect = 0.63
Identities = 32/151 (21%), Positives = 66/151 (43%), Gaps = 13/151 (8%)
Query: 860 WITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISD 919
W +E+ QE K+ E+ + R + E+ K+ + K + K + E
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE----KMQEQEKMRRQEEKIR 574
Query: 920 QEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLRE---------EKKAEKKGKEAGKKK 970
+++EK +E+ I E K W++E+ +EE ++E EK E++ K +++
Sbjct: 575 EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 634
Query: 971 GKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQ 1001
E++ + +EK +E Q ++
Sbjct: 635 KMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 54.7 bits (130), Expect = 1e-06
Identities = 94/410 (22%), Positives = 170/410 (41%), Gaps = 44/410 (10%)
Query: 837 NIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKII----RTRAELELKSSANA 892
+++ H V +++V KS ++ + EE +E+++ E++ + E E K
Sbjct: 431 SVSTHIKVKSEEKIKVVEKSEKETVIVEEQT-EETQVTEEVTEEEEKEAKEEEGKEEEGG 489
Query: 893 KLTSA------SKIFSIKESKSNKGISKTEISDQEK--------EKEKEKIPFILEGSLK 938
+ A +K +E+ S + +K+ + ++ K EKE+ K P ++ K
Sbjct: 490 EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK 549
Query: 939 AWK--EEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEE 996
A +E+ + E + E+++A+ + +K K A++E + KSP K KS +
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 997 QVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKG 1056
+ +SP + E K PT+ + P E E+ K
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS----PEKAKSPEKEEA---KS 662
Query: 1057 PTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEEEEGDEE-QSLETEVSDAKNKA 1115
P K V + + + K K EK ++EE + E+ +S E + + KA
Sbjct: 663 PEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKA 722
Query: 1116 FSKFGSFSATLENGICLSISYYGSNGMAPED-KDPDLETILNI--PSALTP------TVV 1166
S + T E + S +PE K P+ L++ P A TP +
Sbjct: 723 KSPVKEEAKTPEK----AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778
Query: 1167 PVIVTVPQSKAKGKIKGKEKPKESLKEE-EHPKEEEKKEEEVEPEPVLQE 1215
+S K ++K EK K LKE+ + P++E K+EEV+ PV +E
Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK-SPVKEE 827
Score = 50.8 bits (120), Expect = 1e-05
Identities = 90/392 (22%), Positives = 150/392 (38%), Gaps = 49/392 (12%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLT---SASKIFSIKESKSNKGISKTEISD 919
KEEA + + ++ + E KS A AK A +K + K +K E
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648
Query: 920 QEK----EKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNA 975
EK EKE+ K P + +KA E+ + KAE K E K K+ A
Sbjct: 649 PEKAKSPEKEEAKSPEKAKSPVKA------EAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 702
Query: 976 E---------KEDSRSLKK-KSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMG 1025
+ KE+++S +K KSP KE++K + V EE+ + K ++
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK 762
Query: 1026 NIPTQISGSNYYLYPSDGGQIEVEKTMFE--KGPTFIKVRVVKDNHNFMIHLNDPKEIVK 1083
+ + P+D + + + E K P K + +D KEI K
Sbjct: 763 SPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK------APEKEIPK 816
Query: 1084 KEEKGDYYLEEE-----------EEGDEEQSLET----EVSDAKNKAFSKFGSFSATLEN 1128
KEE EEE ++ +EE++ T E D+K + K + +E
Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876
Query: 1129 GICLSISYYGSNGMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPK 1188
++ + + + ++ + + + P P V V +K K K + +K
Sbjct: 877 KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEV---KEDAKPKEKTEVAKKEP 933
Query: 1189 ESLKEEEHPKEEEKKEEEVEPEPVLQETLDVP 1220
+ K +E K EKKE E + +E P
Sbjct: 934 DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKP 965
Score = 50.4 bits (119), Expect = 2e-05
Identities = 88/359 (24%), Positives = 144/359 (40%), Gaps = 34/359 (9%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFS-IKESKSNKGISKTEISDQE 921
KEEA E + ++ + KS A+ S K S +KE + +K+ + ++
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 716
Query: 922 KEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAE-KEDS 980
K EK K P ++ K ++ + + EE + E+ K+ +K K K + KE++
Sbjct: 717 KSPEKAKSP--VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 981 RSLKKKSPYKEKSK-EEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYYLY 1039
RS K P K KS +E+VK E + SP + + K IP + +
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAK-SPLKEDAKAPEK-------EIPKKEEVKSPVKE 826
Query: 1040 PSDGGQIEVE----KTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEE 1095
+++V+ K EK P K KD+ KE K+E +EE+
Sbjct: 827 EEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK---------KEEAPKKEAPKPKVEEK 877
Query: 1096 EEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAPE--DKDPDLET 1153
+E E+ E++V K +A K + E + + E K+PD +
Sbjct: 878 KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD-DA 936
Query: 1154 ILNIPS--ALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPE 1210
PS A P + KAK K +EKPK K +E K K+ + + E
Sbjct: 937 KAKEPSKPAEKKEAAPEKKDTKEEKAK---KPEEKPKTEAKAKEDDKTLSKEPSKPKAE 992
Score = 50.4 bits (119), Expect = 2e-05
Identities = 41/162 (25%), Positives = 69/162 (42%), Gaps = 1/162 (0%)
Query: 854 AKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGIS 913
AK+ + I K+E + K EK + + K + K + K K+SK +
Sbjct: 807 AKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK 866
Query: 914 KTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKD 973
K + +EK++ + E ++A KEE + +E A+ + KE K K K
Sbjct: 867 KEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKT 926
Query: 974 NAEKEDSRSLKKKSPYKEKSKEEQV-KIQEVTEESPHQPEPK 1014
K++ K K P K K+E + ++ EE +PE K
Sbjct: 927 EVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968
Score = 49.7 bits (117), Expect = 3e-05
Identities = 83/358 (23%), Positives = 136/358 (37%), Gaps = 55/358 (15%)
Query: 893 KLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEER 952
K+ S S +K + K + K+E E++ E+ E + + KE + +EE
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487
Query: 953 LREEKKA------------------EKKGKEAGKKKGKDNA-----EKEDSRS-LKKKSP 988
EE++A EK+ K K++ K A EKE+++S + KSP
Sbjct: 488 GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP 547
Query: 989 YKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYYLYPSDGGQIEV 1048
K KS ++ +SP + E K P + + P++ E
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS----PAEAKSPEK 603
Query: 1049 EKTMFE---KGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEEEEGDEEQSLE 1105
K+ + K P K V ++ P E+ E+ EE + ++ +S E
Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEE-------AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
Query: 1106 TEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAPED-KDPDLETILNIPSALTPT 1164
E + + KA S + + + E + S + +PE K P E + A +P
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEK----AKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV 712
Query: 1165 VVPVIVTVPQSKAKGKIKGKEKPKESLKEEE---HPKEEEKKEEEVEPEPVLQETLDV 1219
+ +AK K K KE K E P +EE K E P +TLDV
Sbjct: 713 ---------KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761
Score = 48.1 bits (113), Expect = 9e-05
Identities = 59/274 (21%), Positives = 101/274 (36%), Gaps = 14/274 (5%)
Query: 1796 KEDELQEMMVKDSRTEEERGNAADLLK-LVMSFPKMEETTKSHVTEVAAHLTDLFKQSLA 1854
K E + VK+ E+ + + K L + P+ + K A + K +
Sbjct: 731 KTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVK 790
Query: 1855 TPPKCPPDTFGKDFFEKTWRHTASSKRWKEKIDKTRKEIETTQNYLMDIKNRIIPPFFKS 1914
K P K ++ + KE++ KE E Q ++K + P +
Sbjct: 791 EEVKSPEKA--KSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ----EVKVKEPPKKAEE 844
Query: 1915 ELNQLYQSQYNHLDSLSKKLPSFTK---KNEDANETAVQDTSDLNLDFKPHKVSEQKSSS 1971
E DS ++ P K E+ E AV+ + ++ K + ++K
Sbjct: 845 EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVP 904
Query: 1972 VPSLPKPEISADKKDFTAQNQTENLTKSPEEAESYEPVKIPTQSLLQDVAGQTRKEKVKL 2031
P P K+D + +TE K P++A++ EP K + T++EK K
Sbjct: 905 TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKK 964
Query: 2032 PHYLLSSKPKSQPLAKVQDSVGGKVNTSSVASAA 2065
P KPK++ AK D K + A A
Sbjct: 965 P----EEKPKTEAKAKEDDKTLSKEPSKPKAEKA 994
Score = 41.6 bits (96), Expect = 0.009
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 24/165 (14%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNK---------GIS 913
KEEA +E+ + ++E K + SK+ + KE +K +
Sbjct: 861 KEEAPKKEAP--------KPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPA 912
Query: 914 KTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKK--AEKKGKEAGKKKG 971
K E+ + K KEK ++ KA +E + AE++ EKK E+K K+ +K
Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKA--KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPK 970
Query: 972 KDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKIT 1016
+ KED ++L K+ K K E+ + T++ +P K T
Sbjct: 971 TEAKAKEDDKTLSKE---PSKPKAEKAEKSSSTDQKDSKPPEKAT 1012
Score = 38.5 bits (88), Expect = 0.074
Identities = 39/142 (27%), Positives = 60/142 (42%), Gaps = 11/142 (7%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEK 922
KE A+ E K+ + E E K A +KE K KTE++ +E
Sbjct: 878 KEPAV--EKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPK--EKTEVAKKEP 933
Query: 923 EKEKEKIPFILEGSLKAWKEEQHRLAE-----EERLREEKKAEKKGKEAGKKKGKDNAEK 977
+ K K P +A E++ E EE+ + E KA++ K K+ K AEK
Sbjct: 934 DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 993
Query: 978 EDSRSL--KKKSPYKEKSKEEQ 997
+ S +K S EK+ E++
Sbjct: 994 AEKSSSTDQKDSKPPEKATEDK 1015
Score = 35.8 bits (81), Expect = 0.48
Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 88 SSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKFKDQQRR-EN 146
S +KAK PV A + + KA S EK P+ + + + K++ + E
Sbjct: 662 SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEK 721
Query: 147 EKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGK------DQPEANAPVKK 194
K ++++ K + KAKSP +++A S + AK K PEA P K+
Sbjct: 722 AKSPVKEEAKTPE---KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE 772
Score = 35.8 bits (81), Expect = 0.48
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 4/110 (3%)
Query: 88 SSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKFKDQQRRENE 147
S +KAK PV A + + K S EK P K L + + K ++ +
Sbjct: 718 SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSP 777
Query: 148 KKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGKDQP---EANAPVKK 194
+K K K + KSP++ K+P + AK K+ P E +PVK+
Sbjct: 778 ADKFPEKAK-SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE 826
Score = 34.3 bits (77), Expect = 1.4
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 6/82 (7%)
Query: 139 KDQQRRENEKKVIEDKPKLEKDKGKA-KSPKEKKAPSAK-PAKGKGK-DQPEANAPVKKT 195
KD ++ E KK KPK+E+ K A + PKE K + K A+ K K PE AP K
Sbjct: 857 KDSKKEEAPKKEAP-KPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAK-- 913
Query: 196 TQLKRRGEDDHTNRYIDDEPDD 217
++K + EPDD
Sbjct: 914 VEVKEDAKPKEKTEVAKKEPDD 935
Score = 33.9 bits (76), Expect = 1.8
Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 5/53 (9%)
Query: 144 RENEKKVIEDKPKLEKDKGKAKSPKEKKAP--SAKPAKGKGKDQPEANAPVKK 194
+E K E K +K +AKSP E K+P + PAK + K PEA +P K+
Sbjct: 521 KEEAKSPAEAK---SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKE 570
Score = 33.9 bits (76), Expect = 1.8
Identities = 26/120 (21%), Positives = 52/120 (43%), Gaps = 14/120 (11%)
Query: 88 SSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKFKDQQRRENE 147
S +AK P +P+ E + A+A E+ P ++K ++ + +
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA----------EVKSPEKAKSPTK 643
Query: 148 KKVIEDKPKLEKDKGKAKSPKEKKAP----SAKPAKGKGKDQPEANAPVKKTTQLKRRGE 203
++ + +K +AKSP++ K+P + P K K + EA +P K + +K +
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703
Score = 33.1 bits (74), Expect = 3.1
Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 6/111 (5%)
Query: 86 SASSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKFKDQQRRE 145
S ++AK P +P E + A+ + S EK P K + K +++ +
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSPAE--VKSPEKAKSP--AKEEAKSPPEAKSPEKEEAK 573
Query: 146 NEKKVIEDKPKLEKDKGKAKSPKEKKAP--SAKPAKGKGKDQPEANAPVKK 194
+ +V + K +AKSP E K+P + P K + K EA +PVK+
Sbjct: 574 SPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Score = 33.1 bits (74), Expect = 3.1
Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 4/108 (3%)
Query: 88 SSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKFKDQQRR-EN 146
S +KAK PV A + + K S EK P+ + + + K++ + E
Sbjct: 676 SPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735
Query: 147 EKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGKDQPEANAPVKK 194
K ++++ K + KAKSP++ K K + K + EA +P K
Sbjct: 736 AKSPVKEEAKSPE---KAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780
Score = 32.3 bits (72), Expect = 5.3
Identities = 70/326 (21%), Positives = 120/326 (36%), Gaps = 46/326 (14%)
Query: 1751 SAPGAILKSPSVLQMRQFIQHEVIKNEVKLRLQVSLKDYINYILKKEDELQEMMVKDSRT 1810
S P + K PSV H +K+E K+++ V + I+ E++ +E V + T
Sbjct: 421 SLPEGLPKIPSVST------HIKVKSEEKIKV-VEKSEKETVIV--EEQTEETQVTEEVT 471
Query: 1811 EEERGNAADLLKLVMSFPKMEETTKSHVTEVAAHLTDLFKQSLATPPKCPPDTFGKDFFE 1870
EEE A + K EE + E T +S P+ K +
Sbjct: 472 EEEEKEAKE------EEGKEEEGGEEEEAEGGEEET----KSPPAEEAASPEKEAKSPVK 521
Query: 1871 KTWRHTASSKRWKEKIDKTRKEIETTQNYLMDIKNRI-IPPFFKSELNQLYQSQYNHLDS 1929
+ + A +K +++ K+ E+++ + K PP KS +
Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKE----------- 570
Query: 1930 LSKKLPSFTKKNEDANETAVQDTSDLNLDFKPHKVSEQKSSSVPSLPKPEISADKKDFTA 1989
K P+ K E A A ++ +E KS P E + K A
Sbjct: 571 -EAKSPAEVKSPEKAKSPAKEEAKS---------PAEAKSPEKAKSPVKEEA--KSPAEA 618
Query: 1990 QNQTENLTKSPEEAESYEPVKIPT--QSLLQDVAGQTRKEKVKLPHYLLSS-KPKSQPLA 2046
++ + KSP E +S E K PT ++ + A KE+ K P S K +++
Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE 678
Query: 2047 KVQDSVGGKVNTSSVASAAINNAKSS 2072
K + V + + A + + S
Sbjct: 679 KAKSPVKAEAKSPEKAKSPVKEEAKS 704
Score = 32.3 bits (72), Expect = 5.3
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 7/65 (10%)
Query: 144 RENEKKVIEDKPKLEK-----DKGKAKSPKEKKAPSAKPAKGKGKDQPEANAPVKKTTQL 198
+E + K E+KPK E DK +K P + KA A+ K DQ ++ P K T
Sbjct: 958 KEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAE--KSSSTDQKDSKPPEKATEDK 1015
Query: 199 KRRGE 203
+G+
Sbjct: 1016 AAKGK 1020
Score = 32.0 bits (71), Expect = 7.0
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 160 DKGKAKSPKEKKAP--SAKPAKGKGKDQPEANAPVKKTTQLKRRGE 203
+K +AKSP E K+P + PAK + K EA +P K + +K +
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613
Score = 31.6 bits (70), Expect = 9.1
Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 88 SSKKAKKPVGGNAPLYYEVLTAAKAIMDSGEKLTLPLIGKLLKFQLLQIKFKDQQRR-EN 146
S +KAK P A + + K S EK P+ + + + K + + E
Sbjct: 634 SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK 693
Query: 147 EKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGKDQ---PE-ANAPVKKTTQLKRRG 202
K ++++ K + KAKSP +++A S + AK K++ PE A +PVK+ + +
Sbjct: 694 AKSPVKEEAKSPE---KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKA 750
Query: 203 EDDHTNRYID 212
+ + +D
Sbjct: 751 KSPEKAKTLD 760
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 54.3 bits (129), Expect = 1e-06
Identities = 60/303 (19%), Positives = 133/303 (43%), Gaps = 31/303 (10%)
Query: 723 QESIMKAQPQHESL-EQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLMD 781
QE K + Q E + EQ +++ + + + ++ ++MM E + +K +++ M
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE----EKMRRQEEMM 433
Query: 782 WSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALH 841
W K + + ++ ++ H+Q + + Q+ + RQ + W
Sbjct: 434 WE-----KEEKIRELEEKMHEQEKIREQEEKRQEEEKI---REQEKRQEQEAKMWR---- 481
Query: 842 SNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIF 901
R E + + + +EE I+++ K+ E+ R E E K+ +I+
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIW 539
Query: 902 SIKES---KSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKK 958
KE + K + E +++EK ++ I E K W++E+ +EE++RE+++
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599
Query: 959 AEKKGKEAGKKKGKDNAEKEDS---------RSLKKKSPYKEKSKEEQVKIQEVTEESPH 1009
++ +E +++ + E+E+ +K +EK +E++ KI+E E+
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 659
Query: 1010 QPE 1012
Q E
Sbjct: 660 QEE 662
Score = 47.0 bits (110), Expect = 2e-04
Identities = 40/163 (24%), Positives = 83/163 (50%), Gaps = 12/163 (7%)
Query: 855 KSIQDWITK-----EEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSN 909
+ IQ+W K E+ QE K+ E+ + R + E+ K+ ++ KE K
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427
Query: 910 KGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKK 969
+ + E+ +++EK +E + E + +E++ + EEE++RE++K +++ + ++
Sbjct: 428 R---QEEMMWEKEEKIRELEEKMHEQ--EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 482
Query: 970 KGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPE 1012
+ K ++E R ++K +E+ EQ KI+E EE + E
Sbjct: 483 EEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE--EEKRQEQE 523
Score = 44.3 bits (103), Expect = 0.001
Identities = 72/372 (19%), Positives = 156/372 (41%), Gaps = 32/372 (8%)
Query: 645 QIRQQYVMKMNTQEAK-QKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMK 703
++ QQ KM QE K Q+ + KI+++ + + + E R + M+
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 413
Query: 704 HSDLNNLKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMM 763
+ + E+E M+ Q + ++ E+++ + E++ K+
Sbjct: 414 RQE-----------EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 462
Query: 764 VEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFH 823
E E K+ +Q + M W E + + ++ ++ K +R + H Q+
Sbjct: 463 EEKIREQEKRQEQEAKM-WRQEEKIREQEE-KIREQEEKMWR-QEEKIHEQEK-----IR 514
Query: 824 NPMNRQRLHCEYWNIA--LHSNVGFRNYLELVAKSIQDWITKEEAIY-QESKMNEKIIRT 880
RQ E W + E + + + +EE ++ QE KM+++ +
Sbjct: 515 EEEKRQEQE-EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI 573
Query: 881 RAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAW 940
R + E K+ + +E K + + E++ +++EK E+ + E K
Sbjct: 574 REQEEKVWRQEEKIREQEEKIREQEEKIRE---QEEMTQEQEEKMGEQEEKMCEQEEKMQ 630
Query: 941 KEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKI 1000
++E+ +EE++RE++K ++ +E +++ + E+E+ K +EK E++ K+
Sbjct: 631 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE-----KMWEQEEKMCEQEEKM 685
Query: 1001 QEVTEESPHQPE 1012
QE E+ Q E
Sbjct: 686 QEQEEKMRRQEE 697
Score = 40.0 bits (92), Expect = 0.026
Identities = 28/153 (18%), Positives = 73/153 (47%), Gaps = 15/153 (9%)
Query: 860 WITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISD 919
W +E+ QE K+ E+ + R + E+ K+ + +E K + K +
Sbjct: 581 WRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQE 640
Query: 920 QEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKED 979
++ ++++KI +E++ ++ E+E + +E++ EK ++ K ++ +E
Sbjct: 641 EKIREQEKKI-----------REQEEKIREQEEMMQEQE-EKMWEQEEKMCEQEEKMQEQ 688
Query: 980 SRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPE 1012
++++ +EK E++V++++ E+ E
Sbjct: 689 EEKMRRQ---EEKMWEQEVRLRQQEEKMQEHQE 718
Score = 38.1 bits (87), Expect = 0.097
Identities = 35/150 (23%), Positives = 72/150 (48%), Gaps = 12/150 (8%)
Query: 869 QESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKE---KE 925
QE K+ E+ + R + E K+ KI ++ + + + + E +E+E ++
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541
Query: 926 KEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKK 985
KEKI +EE+ R EE+ R+E+K + ++ +++ K ++E R ++
Sbjct: 542 KEKIHE---------QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE 592
Query: 986 KSPYKEKSKEEQVKIQEVTEESPHQPEPKI 1015
K +E+ EQ ++ + EE + E K+
Sbjct: 593 KIREQEEKIREQEEMTQEQEEKMGEQEEKM 622
Score = 32.0 bits (71), Expect = 7.0
Identities = 47/254 (18%), Positives = 103/254 (40%), Gaps = 39/254 (15%)
Query: 782 WSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALH 841
W F + + L V + K R ++ +D L ++ N + + L
Sbjct: 232 WKFAGELE-QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELK--------E 282
Query: 842 SNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIF 901
N + L+LV K E ++ K+ R + L + A+ K
Sbjct: 283 KNAKLQEKLQLVESE------KSEIQLNVKELKRKLERAKLLLP-QQQLQAEADHLGKEL 335
Query: 902 SIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKE------------EQHRLAE 949
+K + + E+ ++ ++++EK+ + E ++ W+E E+ +
Sbjct: 336 QSVSAKLQAQVEENELWNRLNQQQEEKM-WRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 394
Query: 950 EERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSK--------EEQVKIQ 1001
EE++R +++ + +E +++ + EKE+ +++ ++++ K EQ KI+
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 454
Query: 1002 EVTEESPHQPEPKI 1015
E +E Q E KI
Sbjct: 455 E--QEEKRQEEEKI 466
>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sapiens]
Length = 373
Score = 54.3 bits (129), Expect = 1e-06
Identities = 46/159 (28%), Positives = 74/159 (46%), Gaps = 28/159 (17%)
Query: 904 KESKSNKGISKTEISDQEKEK-----EKEKIPFILEGSLKAW---KEEQHRLAEEERLR- 954
KE + + E +Q+ EK E+EK I E K W K EQ R E+++
Sbjct: 154 KEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINK 213
Query: 955 --EEKKAEKKGKEAGKKKGKDNAE----KEDSRSLKKKSPYKEKSKEEQVKIQEV----- 1003
EEK A++ KE ++K K+ + K+++ ++K KEK K++Q +IQE
Sbjct: 214 EMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAE 273
Query: 1004 ------TEESPHQPEPKITYPFHGYNMGNIPTQISGSNY 1036
E + H+P P +GY G + SG++Y
Sbjct: 274 KKFQEWLENAKHKPRP--AAKSYGYANGKLTGFYSGNSY 310
Score = 32.7 bits (73), Expect = 4.1
Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 13/120 (10%)
Query: 1085 EEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAP 1144
E+ GD E+EE+ D+E+ ++ + D++ K S G + + S +
Sbjct: 79 EDDGDG--EDEEDVDDEEDVDEDAHDSEAKVASLRG-----------MELQGCASTQVES 125
Query: 1145 EDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKKE 1204
E+ + + + S LTP V I + + + ++K E+ + L++ + +E EK++
Sbjct: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRK 185
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 123
Score = 53.5 bits (127), Expect = 2e-06
Identities = 36/107 (33%), Positives = 57/107 (53%), Gaps = 15/107 (14%)
Query: 904 KESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKG 963
K+ K K +TE +E E+E+EK EG K ++E+ R+EK+ +KK
Sbjct: 2 KKKKKKKETEETE-ETEETEEEEEK-----EGKRKEKRKEK---------RKEKEKKKKT 46
Query: 964 KEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQ 1010
KE K+K K+ EK+ R KKK +E+ +EE+ + +E EE +
Sbjct: 47 KETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93
Score = 52.0 bits (123), Expect = 6e-06
Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 10/132 (7%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEK 922
K++ +E++ E+ T E E + K ++ K + K + + EK
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEK----------RKEKRKEKEKKKKTKETEK 51
Query: 923 EKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRS 982
KEKE+ + K KEE+ R EEE EEK+ E+K + +KK K KE+
Sbjct: 52 RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111
Query: 983 LKKKSPYKEKSK 994
KKK K K K
Sbjct: 112 KKKKRRRKTKKK 123
Score = 51.6 bits (122), Expect = 8e-06
Identities = 28/96 (29%), Positives = 56/96 (58%), Gaps = 2/96 (2%)
Query: 904 KESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKG 963
+E + +G K + ++ KEKEK+K E + KEE+ + + +R +++++ E++
Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKT--KETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77
Query: 964 KEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVK 999
+E +++ K+ EKE+ R KKK + K +EE+ K
Sbjct: 78 EEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113
Score = 35.0 bits (79), Expect = 0.82
Identities = 17/37 (45%), Positives = 25/37 (67%)
Query: 1174 QSKAKGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPE 1210
+ + K K K K+K +E +EEE +EEE+KEEE + E
Sbjct: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93
Score = 34.3 bits (77), Expect = 1.4
Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
Query: 957 KKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPE 1012
KK +KK KE + + + E+E+ + K+K KEK KE++ K + T+E+ + E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKK--KKTKETEKRKE 54
Score = 32.3 bits (72), Expect = 5.3
Identities = 16/37 (43%), Positives = 24/37 (64%)
Query: 1174 QSKAKGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPE 1210
+ K + + K K K K+ +EEE +EEE++EEE E E
Sbjct: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEE 89
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 52.8 bits (125), Expect = 4e-06
Identities = 85/364 (23%), Positives = 142/364 (39%), Gaps = 63/364 (17%)
Query: 862 TKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQE 921
TK +E E+ +AE+ K + + K +A + KE+K K E +E
Sbjct: 598 TKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKV-----KPEDKKEE 652
Query: 922 KEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSR 981
KEK K+++ A KE++ + +EE+ ++E+ K+ KK+ K +KE +
Sbjct: 653 KEKPKKEV---------AKKEDKTPIKKEEKPKKEEV-----KKEVKKEIKKEEKKEPKK 698
Query: 982 SLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYYLYPS 1041
+KK++P KE KE VK +E E + EPK + +P S+ L +
Sbjct: 699 EVKKETPPKEVKKE--VKKEEKKEVKKEEKEPK-------KEIKKLPKDAKKSSTPLSEA 749
Query: 1042 DGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEEEEGDEE 1101
K P +K +V K + D K +EKG + ++E G
Sbjct: 750 -------------KKPAALKPKVPKKEESVK---KDSVAAGKPKEKGKIKVIKKE-GKAA 792
Query: 1102 QSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAPEDKDPDLETILNIPSAL 1161
+++ V A + A + G + S +PED D E + +
Sbjct: 793 EAVAAAVGTGATTAAVMAAAGIAAI--GPAKELEAERSLMSSPEDLTKDFEELKAEEVDV 850
Query: 1162 TPTVVPVIVTVPQS---------------KAKGKIKGK-EKPKESLKEEEHPKEEEKKEE 1205
T + P + + K + KG E P E + E E E+ E
Sbjct: 851 TKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPE 910
Query: 1206 EVEP 1209
E+EP
Sbjct: 911 ELEP 914
Score = 50.1 bits (118), Expect = 2e-05
Identities = 35/125 (28%), Positives = 70/125 (56%), Gaps = 5/125 (4%)
Query: 893 KLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEER 952
K+ S K+ +K+ K K +K ++++E ++E P E + K + + + A+E+
Sbjct: 579 KVESKEKVM-VKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKT 637
Query: 953 LREEKKAEKKGKEAGKKKGKDN-AEKEDSRSLKKKS-PYKEKSKEEQVKIQEVTEESPHQ 1010
+++E K + + K+ K+K K A+KED +KK+ P KE+ K+E K E+ +E +
Sbjct: 638 VKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKK--EIKKEEKKE 695
Query: 1011 PEPKI 1015
P+ ++
Sbjct: 696 PKKEV 700
Score = 41.2 bits (95), Expect = 0.011
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 13/165 (7%)
Query: 851 ELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNK 910
E A ++ KE+ + +E+K+ + + E K A + + K KE K K
Sbjct: 622 EKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIK----KEEKPKK 677
Query: 911 GISKTEISDQEKEKEKE--KIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEA-- 966
K E+ + K++EK+ K E K K+E + ++E +EEK+ +K+ K+
Sbjct: 678 EEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPK 737
Query: 967 -GKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQ 1010
KK +E + +LK K P KEE VK V P +
Sbjct: 738 DAKKSSTPLSEAKKPAALKPKVP----KKEESVKKDSVAAGKPKE 778
Score = 35.0 bits (79), Expect = 0.82
Identities = 63/273 (23%), Positives = 103/273 (37%), Gaps = 60/273 (21%)
Query: 861 ITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQ 920
+ K+ + Q + E + L KS + SK + + +K N ++ +
Sbjct: 529 VVKQTKLKQRADSRESLKPAAKPLPSKS-----VRKESKEETPEVTKVNHVEKPPKVESK 583
Query: 921 EKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDS 980
EK K+ P E ++E E ++ E AEK+ + K K+ K+++
Sbjct: 584 EKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEV-AEKQATDVKPKAAKEKTVKKET 642
Query: 981 R-SLKKKSPYKEKSKEEQVKIQEVT----EESPHQPEPKITYPFHGYNMGNIPTQISGSN 1035
+ + K KEK K+E K ++ T EE P + E K
Sbjct: 643 KVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVK--------------------- 681
Query: 1036 YYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEI---VKKEEKGDYYL 1092
EV+K + ++ K V K+ PKE+ VKKEEK +
Sbjct: 682 ----------KEVKKEIKKEEKKEPKKEVKKE--------TPPKEVKKEVKKEEKKEVKK 723
Query: 1093 EEEEEGDEEQSL-------ETEVSDAKNKAFSK 1118
EE+E E + L T +S+AK A K
Sbjct: 724 EEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALK 756
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 52.8 bits (125), Expect = 4e-06
Identities = 73/328 (22%), Positives = 133/328 (40%), Gaps = 30/328 (9%)
Query: 690 EPSDPSQCDANNMKHSDLNNLKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAV 749
EP PS A+ +K D DN E AQ + + EQ ++ +
Sbjct: 290 EPERPSILSASELKELDKF-------DNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGS 342
Query: 750 TKADSHEKKPKKMMVEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQE--AHKQYRCV 807
+ + + + E+ K+T + S S +P V + + Q R
Sbjct: 343 NSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGT 402
Query: 808 DSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAI 867
S+ LL H P +RQ A+ G + VA + W +
Sbjct: 403 SSHLPPPPK-LLAQQHPPPDRQ---------AVPGRPGPFPSKQQVADEDEIWKQRRRQQ 452
Query: 868 YQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKS--NKGISKTEISDQEKEKE 925
+ S E+ + R E E + K A K+ + E K S EI ++E+EKE
Sbjct: 453 SEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKE 512
Query: 926 KEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKK 985
+E+ K ++EQ + E+ER ++ ++ ++K KE K++ K +++ + K+
Sbjct: 513 RER--------EKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE 564
Query: 986 KSPYKEKSKEEQV-KIQEVTEESPHQPE 1012
K ++K KE+++ K++E +E + E
Sbjct: 565 KELERQKEKEKELQKMKEQEKECELEKE 592
Score = 39.7 bits (91), Expect = 0.033
Identities = 29/119 (24%), Positives = 59/119 (49%), Gaps = 6/119 (5%)
Query: 904 KESKSNKGISKTEISDQEKE------KEKEKIPFILEGSLKAWKEEQHRLAEEERLREEK 957
KE + K + K + ++EKE +++EK + + K + E+ R E+E+ E +
Sbjct: 511 KEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQ 570
Query: 958 KAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKIT 1016
K ++K + K++ K+ +++ L++K +E + E V+ QE + EP T
Sbjct: 571 KEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFT 629
Score = 34.7 bits (78), Expect = 1.1
Identities = 25/114 (21%), Positives = 59/114 (51%), Gaps = 4/114 (3%)
Query: 902 SIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEK 961
+++ ++ + + + +Q K EK+ + E K E+ EE R RE +K +
Sbjct: 458 AVERARKRREEEERRMEEQRKAACAEKLKRLDE---KLGILEKQPSPEEIREREREKERE 514
Query: 962 KGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKI 1015
+ KE K++ ++ EKE + +++ +++ ++EQ K +E+ +E + E ++
Sbjct: 515 REKELEKEQEQER-EKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKEL 567
Score = 34.3 bits (77), Expect = 1.4
Identities = 31/122 (25%), Positives = 48/122 (39%), Gaps = 21/122 (17%)
Query: 644 KQIRQQYVMKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMK 703
+QI Y ++ N EA KAD + V + LS SV+D P DANN
Sbjct: 841 EQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVR-------PHHTDANN-- 891
Query: 704 HSDLNNLKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMM 763
+ PD + L + PQ E + + + +V+ +H +KP +
Sbjct: 892 ----QSACFEAPDQKTL--------SAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQR 939
Query: 764 VE 765
E
Sbjct: 940 SE 941
Score = 33.5 bits (75), Expect = 2.4
Identities = 36/142 (25%), Positives = 58/142 (40%), Gaps = 31/142 (21%)
Query: 1078 PKEIVKKEEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYY 1137
P+EI ++E + + E+E E ++EQ E E + + K E +
Sbjct: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKE-- 558
Query: 1138 GSNGMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHP 1197
++K+ +LE + K K K +K KE KE E
Sbjct: 559 -----RKQEKEKELE-----------------------RQKEKEKELQKMKEQEKECELE 590
Query: 1198 KEEEKKEEEVEP-EPVLQETLD 1218
KE EK EE++EP EP L+ ++
Sbjct: 591 KEREKLEEKIEPREPNLEPMVE 612
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 52.0 bits (123), Expect = 6e-06
Identities = 42/167 (25%), Positives = 81/167 (48%), Gaps = 13/167 (7%)
Query: 858 QDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIF----SIKESKSNKGIS 913
Q+W+ K+ E ++I ++ + AK A F ++KE ++ K +
Sbjct: 430 QEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAA 489
Query: 914 KTEISDQEKEKEKEKIPFILEGSLKA---WKEEQHRLAEEERLRE---EKKAEKKGKEAG 967
K + ++ K+K +E+ +L+A WKE++ +E+ +E E+ ++K +E
Sbjct: 490 KKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETV 549
Query: 968 KKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPK 1014
+K KDN + + KK++ +K+K KE KI E +E + E K
Sbjct: 550 AEKKKDNLTAVEKWNEKKEAFFKQKEKE---KINEKRKEELKRAEKK 593
Score = 33.1 bits (74), Expect = 3.1
Identities = 77/442 (17%), Positives = 162/442 (36%), Gaps = 56/442 (12%)
Query: 608 KLSEVDEKGKLKPSGMMCGSDSEMFNIPWDNPARFAKQIRQQYVMKMNTQEAKQKADIKI 667
K S ++EK L+ + E+ + P P Q+ + + + +
Sbjct: 184 KKSHMEEKDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSL 243
Query: 668 KDRTL--FVDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLKLSVPDNRQLLEQES 725
+L + + S + N S ++P++ + N++K + S +E+
Sbjct: 244 ASSSLKQILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSK 303
Query: 726 IMKAQPQHESLEQTTNNEIKDD------------AVTKADSHEKKPKKMMVEADLEDIKK 773
+ E+ I DD ++ + S KK + + ++++ K
Sbjct: 304 ESQVTADDLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKS 363
Query: 774 TQQRS------LMDWSFTEHFKPKV-------------LLQVLQEAHKQYRCVDSYYHTQ 814
T R+ LM F + K L+VL + Q + ++
Sbjct: 364 TNNRASSASARLMTSEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEP--DRA 421
Query: 815 DNSLLLVFHNPMNRQRLHCEYWNIALH---SNVGFRNYLELVAKSIQDWITKEEAIYQES 871
DN V+ + ++ ++ + N+ +N + AK ++ + EA
Sbjct: 422 DNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKR-EEALASFEAWKAMK 480
Query: 872 KMNEKIIRTRAELELKSSANAKLTSASK-------IFSIKESK----SNKGISKTEISDQ 920
+ K I + LE K+ + +A++ KE K K + E
Sbjct: 481 EKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERA 540
Query: 921 EKEKEKEKIPFILEGSLKA---WKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEK 977
+K+KE+E + + +L A W E++ ++ +E++K +K KE K+ K + +K
Sbjct: 541 KKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQ---KEKEKINEKRKEELKRAEKKDKDK 597
Query: 978 EDSRSLKKKSPYKEKSKEEQVK 999
+ +K KEK + + K
Sbjct: 598 QAINEYEKWLENKEKQERIERK 619
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 51.6 bits (122), Expect = 8e-06
Identities = 32/119 (26%), Positives = 64/119 (53%), Gaps = 3/119 (2%)
Query: 902 SIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEK 961
S+ +K + +S +E+ K+ K+ E S KA ++++ RL +++R +E+K+ +K
Sbjct: 16 SLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVS-KAPEDKKKRLEDDKRKKEDKERKK 74
Query: 962 KGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFH 1020
K +E K K ++ ++K++ KK + K +EEQ K Q+ E + E + + H
Sbjct: 75 KDEE--KVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
Score = 42.7 bits (99), Expect = 0.004
Identities = 33/136 (24%), Positives = 70/136 (51%), Gaps = 13/136 (9%)
Query: 882 AELELKSSA---NAKLTSASKIFSIKESKSN--KGISKTEISDQEKEKEKEKIPFILEGS 936
A +E K S K S + S KE + K +K E+S ++K+K LE
Sbjct: 9 ASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKR-----LEDD 63
Query: 937 LKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKED---SRSLKKKSPYKEKS 993
+ ++++ + +EE+++ E++++KK +E KK ++ +K++ R ++++ + K
Sbjct: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
Query: 994 KEEQVKIQEVTEESPH 1009
KEE +++ + E H
Sbjct: 124 KEESIQLHQEAWERHH 139
Score = 39.3 bits (90), Expect = 0.044
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 924 KEKEKIPFILEGSLKAWKEEQHRLAEEERLREE-----KKAEKKGKEAGKKKGKDNAEKE 978
+EK+ +P E E+ ++ +ER +++ KK K E KK+ +D+ K+
Sbjct: 12 EEKDSLPNNKEKDCS----ERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKK 67
Query: 979 DSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPK 1014
+ + KKK K K++EE K +E E+ HQ E +
Sbjct: 68 EDKERKKKDEEKVKAEEESKKKEE-EEKKKHQEEER 102
Score = 38.9 bits (89), Expect = 0.057
Identities = 32/133 (24%), Positives = 65/133 (48%), Gaps = 11/133 (8%)
Query: 879 RTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLK 938
R + +++L + K +++ K K + + D+EK K +E+ S K
Sbjct: 36 RPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEE-------SKK 88
Query: 939 AWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEK-SKEEQ 997
+EE+ + EEER ++E++A+++ +E + K EKE+S L +++ + KE +
Sbjct: 89 KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK---EKEESIQLHQEAWERHHLRKELR 145
Query: 998 VKIQEVTEESPHQ 1010
K Q + P +
Sbjct: 146 SKNQNAPDSRPEE 158
Score = 33.9 bits (76), Expect = 1.8
Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 5/65 (7%)
Query: 141 QQRRENEKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGKDQPEANAPVKKTTQLKR 200
++R E++K+ EDK + +KD+ K K+ +E K K + K K Q E K+ Q KR
Sbjct: 57 KKRLEDDKRKKEDKERKKKDEEKVKAEEESK---KKEEEEKKKHQEEERK--KQEEQAKR 111
Query: 201 RGEDD 205
+ E++
Sbjct: 112 QQEEE 116
Score = 31.6 bits (70), Expect = 9.1
Identities = 16/71 (22%), Positives = 34/71 (47%)
Query: 144 RENEKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGKDQPEANAPVKKTTQLKRRGE 203
++ K EDK K +D + K KE+K + K + + + + KK + +R+ +
Sbjct: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ 105
Query: 204 DDHTNRYIDDE 214
++ R ++E
Sbjct: 106 EEQAKRQQEEE 116
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 51.6 bits (122), Expect = 8e-06
Identities = 32/119 (26%), Positives = 64/119 (53%), Gaps = 3/119 (2%)
Query: 902 SIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEK 961
S+ +K + +S +E+ K+ K+ E S KA ++++ RL +++R +E+K+ +K
Sbjct: 16 SLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVS-KAPEDKKKRLEDDKRKKEDKERKK 74
Query: 962 KGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFH 1020
K +E K K ++ ++K++ KK + K +EEQ K Q+ E + E + + H
Sbjct: 75 KDEE--KVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
Score = 42.7 bits (99), Expect = 0.004
Identities = 33/136 (24%), Positives = 70/136 (51%), Gaps = 13/136 (9%)
Query: 882 AELELKSSA---NAKLTSASKIFSIKESKSN--KGISKTEISDQEKEKEKEKIPFILEGS 936
A +E K S K S + S KE + K +K E+S ++K+K LE
Sbjct: 9 ASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKR-----LEDD 63
Query: 937 LKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKED---SRSLKKKSPYKEKS 993
+ ++++ + +EE+++ E++++KK +E KK ++ +K++ R ++++ + K
Sbjct: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
Query: 994 KEEQVKIQEVTEESPH 1009
KEE +++ + E H
Sbjct: 124 KEESIQLHQEAWERHH 139
Score = 39.3 bits (90), Expect = 0.044
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 924 KEKEKIPFILEGSLKAWKEEQHRLAEEERLREE-----KKAEKKGKEAGKKKGKDNAEKE 978
+EK+ +P E E+ ++ +ER +++ KK K E KK+ +D+ K+
Sbjct: 12 EEKDSLPNNKEKDCS----ERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKK 67
Query: 979 DSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPK 1014
+ + KKK K K++EE K +E E+ HQ E +
Sbjct: 68 EDKERKKKDEEKVKAEEESKKKEE-EEKKKHQEEER 102
Score = 38.9 bits (89), Expect = 0.057
Identities = 32/133 (24%), Positives = 65/133 (48%), Gaps = 11/133 (8%)
Query: 879 RTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLK 938
R + +++L + K +++ K K + + D+EK K +E+ S K
Sbjct: 36 RPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEE-------SKK 88
Query: 939 AWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEK-SKEEQ 997
+EE+ + EEER ++E++A+++ +E + K EKE+S L +++ + KE +
Sbjct: 89 KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK---EKEESIQLHQEAWERHHLRKELR 145
Query: 998 VKIQEVTEESPHQ 1010
K Q + P +
Sbjct: 146 SKNQNAPDSRPEE 158
Score = 33.9 bits (76), Expect = 1.8
Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 5/65 (7%)
Query: 141 QQRRENEKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGKDQPEANAPVKKTTQLKR 200
++R E++K+ EDK + +KD+ K K+ +E K K + K K Q E K+ Q KR
Sbjct: 57 KKRLEDDKRKKEDKERKKKDEEKVKAEEESK---KKEEEEKKKHQEEERK--KQEEQAKR 111
Query: 201 RGEDD 205
+ E++
Sbjct: 112 QQEEE 116
Score = 31.6 bits (70), Expect = 9.1
Identities = 16/71 (22%), Positives = 34/71 (47%)
Query: 144 RENEKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGKDQPEANAPVKKTTQLKRRGE 203
++ K EDK K +D + K KE+K + K + + + + KK + +R+ +
Sbjct: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ 105
Query: 204 DDHTNRYIDDE 214
++ R ++E
Sbjct: 106 EEQAKRQQEEE 116
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens]
Length = 1031
Score = 50.4 bits (119), Expect = 2e-05
Identities = 53/229 (23%), Positives = 98/229 (42%), Gaps = 12/229 (5%)
Query: 879 RTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLK 938
R R +S +S+ S K ++ KT+ + KEK+K+K E
Sbjct: 88 RDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKD 147
Query: 939 AWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAE--KEDSRSLKKKSPYKEKSKEE 996
A +Q++L EE +R+ K+ +K +E +KK +N K++ +K+ + + ++
Sbjct: 148 AGNFDQNKL--EEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDD 205
Query: 997 QVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKG 1056
E+ ++ E + P Y M + ++ N GG EK + G
Sbjct: 206 DEDDPAEAEKEGNEMEGEELDPLDAY-MEEVKEEVKKFNMRSVKGGGGN---EK---KSG 258
Query: 1057 PTFIKVRVVKDNHNFMIHLNDPK-EIVKKEEKGDYYLEEEEEGDEEQSL 1104
PT KV V ++ + K E+++ ++ Y EEEE D + +L
Sbjct: 259 PTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTAL 307
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 49.7 bits (117), Expect = 3e-05
Identities = 78/378 (20%), Positives = 158/378 (41%), Gaps = 47/378 (12%)
Query: 645 QIRQQYVMKMNTQEAK-QKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMK 703
++ QQ KM QE K Q+ + KI+++ + + + E R + M+
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 704 HSDLNNLKLSVPDNRQ---LLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPK 760
+ + RQ + E+E M+ Q + ++ E+++ + E++ K
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Query: 761 KMMVEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLL 820
+ E E K+ +Q + M W E + + + ++E K+ + H Q+
Sbjct: 413 RQEEEKIREQEKRQEQEAKM-WRQEEKIREQE--EKIREQEKKMWRQEEKIHEQEK---- 465
Query: 821 VFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMN---EKI 877
RQ E W E + + + W KE+ QE K+ EK+
Sbjct: 466 -IREEEKRQEQE-EMWRQE-----------EKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 878 IRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKE-KEKEKIPFILEGS 936
R ++ + I+E + + +I +QE+ +E+EK +
Sbjct: 513 WRQEEKIREQEE------------KIREQEEKMWRQEEKIREQEEMWREEEK----MHEQ 556
Query: 937 LKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYK--EKSK 994
K W+EE+ + E++ R+E+K ++ ++ +++ K E+E+ R +++ +K EK +
Sbjct: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR-EQEEKRQEQEEKMWKQEEKIR 615
Query: 995 EEQVKIQEVTEESPHQPE 1012
E++ KIQE E+ Q E
Sbjct: 616 EQEEKIQEQEEKIREQEE 633
Score = 48.1 bits (113), Expect = 9e-05
Identities = 61/318 (19%), Positives = 135/318 (42%), Gaps = 38/318 (11%)
Query: 723 QESIMKAQPQHESL-EQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLMD 781
QE K + Q E + EQ +++ + + + ++ ++MM E + +K +++ M
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE----EKMRRQEEMM 372
Query: 782 WSFTEHF---------KPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLH 832
W E K + + ++ ++ H+Q + + Q+ + RQ
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI---REQEKRQEQE 429
Query: 833 CEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANA 892
+ W R E + + + +EE I+++ K+ E+ R E E
Sbjct: 430 AKMWR----QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEE 483
Query: 893 KLTSASKIFSIKES---KSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQ----- 944
K+ +I+ KE + K + E +++EK +E+ I E K W++E+
Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 543
Query: 945 -------HRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQ 997
++ E+E++ EE+K +++ + +++ K ++E ++K +E+ ++EQ
Sbjct: 544 EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQ 603
Query: 998 VKIQEVTEESPHQPEPKI 1015
+ EE + E KI
Sbjct: 604 EEKMWKQEEKIREQEEKI 621
Score = 46.2 bits (108), Expect = 4e-04
Identities = 67/361 (18%), Positives = 148/361 (40%), Gaps = 35/361 (9%)
Query: 653 KMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLKL 712
K+ QE K++ + KI+++ +Q M Q+ + + + + + + + +
Sbjct: 405 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 464
Query: 713 SVPDNRQLLEQESIMKAQPQ-HESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDI 771
+ + + EQE + + + + HE E E + K E+K + + ++
Sbjct: 465 KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEE 524
Query: 772 KKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRL 831
K +Q M W E ++E + +R + H Q+ RQ
Sbjct: 525 KIREQEEKM-WRQEEK---------IREQEEMWR-EEEKMHEQEK-----IWEEEKRQEQ 568
Query: 832 HCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSAN 891
+ W R ++ + + W +E+ QE K E+ + + E
Sbjct: 569 EDKMW----------RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 892 AKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEE 951
K+ + +E K + + E++ +++EK E+ + E K ++E+ +EE
Sbjct: 619 EKIQEQEEKIREQEEKIRE---QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675
Query: 952 RLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQP 1011
++RE++K ++ +E +++ + E+E+ K +EK E++ K+QE E+ Q
Sbjct: 676 KIREQEKKIREQEEKIREQEEMMQEQEE-----KMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Query: 1012 E 1012
E
Sbjct: 731 E 731
Score = 41.2 bits (95), Expect = 0.011
Identities = 65/306 (21%), Positives = 133/306 (43%), Gaps = 42/306 (13%)
Query: 722 EQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLMD 781
EQE I + + + + E+ E + + K E+K ++ E+ + Q++ +
Sbjct: 402 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ------EEKIREQEKKMWR 455
Query: 782 WSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALH 841
H + K+ + ++ ++ + H Q+ ++++H + I
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW-------RQKEKMHEQEEKI--- 505
Query: 842 SNVGFRNYLELVAKSIQDWITKEEAIY-QESKM--NEKIIRTRAEL---ELKSSANAKLT 895
R E V + + +EE I QE KM E+ IR + E+ E K K+
Sbjct: 506 -----RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW 560
Query: 896 SASKIFSIKESKSNKGISKTEISDQEK------EKEKEKIPFILEGSLKAWKEEQHRLAE 949
K +E + + +I +QE+ EK +E+ E K WK+E+ +
Sbjct: 561 EEEKR---QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
Query: 950 EERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPH 1009
EE+++E+++ ++ +E +++ + E+E+ K +EK E++ K+QE EE+
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEE-----KMGEQEEKMCEQEEKMQE-QEETMW 671
Query: 1010 QPEPKI 1015
+ E KI
Sbjct: 672 RQEEKI 677
Score = 31.6 bits (70), Expect = 9.1
Identities = 31/145 (21%), Positives = 72/145 (49%), Gaps = 17/145 (11%)
Query: 870 ESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKI 929
+ ++ EK + + +L+L S +++ ++KE K +K + Q+ + E + +
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQ-----LNVKELKRKLERAKLLLPQQQLQAEADHL 270
Query: 930 PFILEG---SLKAWKEEQ------HRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDS 980
L+ L+A EE ++ EE+ R+E+K ++ ++ +++ K ++E
Sbjct: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 981 RSLKKKSPYKEK---SKEEQVKIQE 1002
R ++K +E+ KEE+++ QE
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQE 355
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 49.7 bits (117), Expect = 3e-05
Identities = 43/168 (25%), Positives = 81/168 (48%), Gaps = 18/168 (10%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEK 922
+EE + +E +M E+ + R E E+ K+ + +E K + K + +++
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640
Query: 923 EKEKEKI----------PFILEGSLKAWK----EEQHRLAE-EERLREEKKAEKKGKEAG 967
+++EK+ + E K W+ +EQ ++ E EE++ E++K EKK +E
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700
Query: 968 KKKGKDN--AEKEDSRSLKKKSPYKEK-SKEEQVKIQEVTEESPHQPE 1012
KK E+E R +KK +E+ +E++ K+QE E+ Q E
Sbjct: 701 KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Score = 44.3 bits (103), Expect = 0.001
Identities = 71/392 (18%), Positives = 165/392 (42%), Gaps = 51/392 (13%)
Query: 636 WDNPARFAKQIR-QQYVMKMNTQEAKQKADIKIKDRTLFV-DQNLSMSVQDNESNREPSD 693
W+ + ++ + Q+ K QE K + + +I++R + ++ +M Q+ + ++ +
Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Query: 694 PSQCDANNMKHSDLNNLKLSVPDNRQLLEQES-IMKAQPQHESLEQTTNNEIK------- 745
+ + + L K + + ++ EQE I + + + E+ E K
Sbjct: 480 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 539
Query: 746 ---DDAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHK 802
+D + + + + ++ M + + KKTQ++ W E + + + ++E K
Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREE---ERMREREK 596
Query: 803 QYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWIT 862
+ R + Q+ + Q + W ++ + + W
Sbjct: 597 KMREEEEMMREQEEKMQ---EQEEKMQEQEEKMWE----------QEEKMQEQEEKMWEQ 643
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEK 922
+E+ QE KM E+ + E + K + K+ K+ +E +I +QEK
Sbjct: 644 EEKMWEQEEKMWEQ--QRLPEQKEKLWEHEKMQEQEKMQEQEE----------KIWEQEK 691
Query: 923 EKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRS 982
++K + E K W +E+ R EEE +RE +K ++ +E +++ + E+E+
Sbjct: 692 MEKKTQ-----EQEKKTWDQEKMR--EEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744
Query: 983 LKKKSPYKEKSK--EEQVKIQEVTEESPHQPE 1012
+++ ++++ K E++ K+ E + P Q E
Sbjct: 745 EQEEEMWEQEEKMWEQEEKMWE-QQRLPEQKE 775
Score = 43.5 bits (101), Expect = 0.002
Identities = 39/171 (22%), Positives = 79/171 (46%), Gaps = 17/171 (9%)
Query: 860 WITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFS----IKESKSNKGISKT 915
W ++ QE ++ E+ R + EL+ K++ ++E + +
Sbjct: 317 WRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 376
Query: 916 EISDQEKEKEKEKIPFILEGSLKAW------KEEQHRLAEEERLRE--EKKAEKKGKEAG 967
+ +QEK+ +E+ + + + W +E++ R+ E+E++ E EK E+K +
Sbjct: 377 RLWEQEKQM-REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQ 435
Query: 968 KKKGKDNAEK----EDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPK 1014
+KK +D EK E R +KK +E++ EQ + + EE+ + E K
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Score = 43.1 bits (100), Expect = 0.003
Identities = 62/298 (20%), Positives = 131/298 (43%), Gaps = 33/298 (11%)
Query: 719 QLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEAD-LEDIKKTQQR 777
+L EQE M+ Q Q + +Q +D+ + + + ++ +KM + + + + KK Q++
Sbjct: 377 RLWEQEKQMREQEQ-KMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQ 435
Query: 778 SLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWN 837
E + + + ++E K+ R + Q+ + N ++ +
Sbjct: 436 EKKTRDQEEKMQEE---ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492
Query: 838 IALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAEL---ELKSSANAKL 894
+ + + +Q+ +EE I+++ E+ IR + E+ E K K+
Sbjct: 493 LPEQKEKLWEQ------EKMQE---QEEKIWEQ----EEKIRDQEEMWGQEKKMWRQEKM 539
Query: 895 TSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLR 954
+E K + ++ DQE+ EK+ E K W +E+ ++ EEER+R
Sbjct: 540 REQEDQMWEQEEKMRD--QEQKMWDQEERMEKKT----QEQEKKTWDQEE-KMREEERMR 592
Query: 955 EEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPE 1012
E +K ++ +E +++ + E+E+ K +EK E++ K+QE E+ Q E
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEE-----KMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Score = 41.6 bits (96), Expect = 0.009
Identities = 34/154 (22%), Positives = 72/154 (46%), Gaps = 6/154 (3%)
Query: 860 WITKEEAIYQESKMNEKIIRT-RAELELKSSANAKLTSASKIFSIKESKSNKGISKTEIS 918
W +E QE KM E+ + R E L+ ++ KE + + E
Sbjct: 296 WRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQE-----EQM 350
Query: 919 DQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKE 978
+++EK E+ + E K W++E+ +E+++RE+++ + +E ++ + EKE
Sbjct: 351 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 410
Query: 979 DSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPE 1012
+ ++K + + E+ K+QE +++ Q E
Sbjct: 411 ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Score = 40.8 bits (94), Expect = 0.015
Identities = 36/153 (23%), Positives = 78/153 (50%), Gaps = 6/153 (3%)
Query: 860 WITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISD 919
W +E QE +M E+ + R + E + +L + +E K + + K + +
Sbjct: 372 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE-KMWEQVEK--MRE 428
Query: 920 QEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKED 979
++K +E+EK E ++ EE+ E+++REE++ ++ +E +K+ ++ E+E+
Sbjct: 429 EKKMQEQEKKTRDQEEKMQ---EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 485
Query: 980 SRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPE 1012
+++ P +++ EQ K+QE E+ Q E
Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518
Score = 40.8 bits (94), Expect = 0.015
Identities = 39/162 (24%), Positives = 77/162 (47%), Gaps = 9/162 (5%)
Query: 858 QDWITKEEAIYQESKM---NEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISK 914
Q W +E+ QE KM E++ + E E K+ + + +E K + +
Sbjct: 545 QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE---E 601
Query: 915 TEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERL--REEKKAEKKGKEAGKKKGK 972
E+ +++EK +E+ + E K W++E+ +EE++ +EEK E++ K +++
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 973 DNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPK 1014
+ EK K + K + +EE++ QE E+ + E K
Sbjct: 662 EQKEKLWEHE-KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Score = 40.8 bits (94), Expect = 0.015
Identities = 79/386 (20%), Positives = 152/386 (39%), Gaps = 66/386 (17%)
Query: 636 WDNPARFAKQIRQQYVMKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPS 695
WD R K+ ++Q K QE K + + ++++R + + M + E +E +
Sbjct: 561 WDQEERMEKKTQEQE-KKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 619
Query: 696 QCDANNMKHSDLNNLKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSH 755
Q M + + ++ EQE M Q + + EQ E K+ K H
Sbjct: 620 QEQEEKMWEQE----EKMQEQEEKMWEQEEKMWEQ-EEKMWEQQRLPEQKE----KLWEH 670
Query: 756 EKKPKKMMVEADLEDI-------KKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVD 808
EK ++ ++ E I KKTQ++ W E + + + ++E K+ R +
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD-QEKMREE---ESMREREKKMREEE 726
Query: 809 SYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIY 868
Q+ M Q ++ + + W +E+
Sbjct: 727 EMMREQEEK--------MQEQEE-------------------KMQEQEEEMWEQEEKMWE 759
Query: 869 QESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEK 928
QE KM E+ + E + K + K+ KI+ +E K K +++ ++EK
Sbjct: 760 QEEKMWEQ--QRLPEQKEKLWEHEKMQEQEKIWE-QEEKMRDQEEKMRGQEEKMRGQEEK 816
Query: 929 IPFILEGSLKAWKEEQHRLAEEERL--REEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKK 986
+ E K W +E+ +EE++ +EEK ++ K K +G++ +E
Sbjct: 817 MRGQEE---KMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ------- 866
Query: 987 SPYKEKSKEEQVKIQEVTEESPHQPE 1012
+EK + ++ K++E E+ Q E
Sbjct: 867 ---EEKMRGQEEKMREQEEKMRGQEE 889
Score = 40.0 bits (92), Expect = 0.026
Identities = 42/174 (24%), Positives = 84/174 (48%), Gaps = 14/174 (8%)
Query: 849 YLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKS 908
Y+E + K +D ++ E +Y+ + NE++ + AEL+ K S ++ ++KE K
Sbjct: 198 YIEELTKE-RDALSLE--LYRNTITNEELKKKNAELQEKLPLAESEKSEIQL-NVKELKR 253
Query: 909 NKGISK-------TEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEK 961
+K T +E +++E++ E K K+E+ +EERLRE++ +
Sbjct: 254 KLERAKFLLPQVQTNTLQEEMWRQEEELR---EQEKKIRKQEEKMWRQEERLREQEGKMR 310
Query: 962 KGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKI 1015
+ +E ++ K E+E ++K ++K EQ + + EE + E K+
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM 364
Score = 37.7 bits (86), Expect = 0.13
Identities = 62/326 (19%), Positives = 134/326 (41%), Gaps = 35/326 (10%)
Query: 719 QLLEQESIMKAQPQ-----HESLEQTTNNEIK-----DDAVTKADSHEKKPKKMMVEADL 768
Q+ EQE M+ Q Q E +E+ T + K ++ + + + ++ KKM E ++
Sbjct: 545 QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 604
Query: 769 ---------EDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQ---DN 816
E +K Q++ W E + + ++ ++ K + + + Q +
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE-KMWEQEEKMWEQEEKMWEQQRLPEQ 663
Query: 817 SLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEK 876
L H M Q E + + +E + + +E + +E M E+
Sbjct: 664 KEKLWEHEKMQEQEKMQEQ-----EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 877 IIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEK-EKEKIPFILEG 935
+ R E E+ K+ + ++E + + ++ +QE++ E++++P E
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEE--KMQEQEEEMWEQEEKMWEQEEKMWEQQRLP---EQ 773
Query: 936 SLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKE 995
K W+ E+ + E+ +EEK +++ K G+++ K ++E R ++K +E+
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEE-KMRGQEEKMRGQEEKMWGQEEKMW 832
Query: 996 EQVKIQEVTEESPHQPEPKITYPFHG 1021
Q + EE E K+ G
Sbjct: 833 GQEEKMWGQEEKMWGQEEKMEEKMQG 858
Score = 35.0 bits (79), Expect = 0.82
Identities = 35/195 (17%), Positives = 84/195 (43%), Gaps = 16/195 (8%)
Query: 920 QEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKED 979
+++E+ +E+ + E K W++E+ +E+ LRE++K ++ KE +++ + ++E
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEE- 355
Query: 980 SRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYYLY 1039
K +EK +E++ K+ E Q + M ++ ++
Sbjct: 356 -----KMWEQEEKMREQEEKMWRQEERLWEQEK----------QMREQEQKMRDQEERMW 400
Query: 1040 PSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEEEEGD 1099
D E E+ M E+ + +V +++ ++ +K ++ + E E++
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMR 460
Query: 1100 EEQSLETEVSDAKNK 1114
EE+ E + K
Sbjct: 461 EEEETMREQEEKMQK 475
Score = 33.5 bits (75), Expect = 2.4
Identities = 36/158 (22%), Positives = 71/158 (44%), Gaps = 14/158 (8%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEK 922
+E+ QE KM E+ + R + E +L K +E K + D+
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406
Query: 923 EKEKEKIPFILEGSLKAWKE-----EQHRLAEEE---RLREEKKAEKKGKEAGKKKGKDN 974
+++E+ + K W++ E+ ++ E+E R +EEK E++ +KK ++
Sbjct: 407 REKEER----MREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE- 461
Query: 975 AEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPE 1012
E+E R ++K +E++ EQ + + + P Q E
Sbjct: 462 -EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 498
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 49.7 bits (117), Expect = 3e-05
Identities = 47/156 (30%), Positives = 76/156 (48%), Gaps = 15/156 (9%)
Query: 838 IALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSA 897
I L +++ N L+ V K +D KEE + + K+ EK + E LK K T+
Sbjct: 672 ILLENDLSTENKLK-VLKHDRDHFKKEEKL-SKMKLEEKEWLFKDEKSLK---RIKDTNK 726
Query: 898 SKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEK 957
S +E K ++ E S +EK ++EK L+ +KEE+ + +++ + EK
Sbjct: 727 DISRSFREEKDRSNKAEKERSLKEKSPKEEK--------LRLYKEERKKKSKDRPSKLEK 778
Query: 958 KAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKS 993
K + K + K+K K KED LKK+ Y+E S
Sbjct: 779 KNDLKEDKISKEKEK--IFKEDKEKLKKEKVYREDS 812
Score = 42.0 bits (97), Expect = 0.007
Identities = 42/166 (25%), Positives = 85/166 (51%), Gaps = 20/166 (12%)
Query: 861 ITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGIS-KTEISD 919
+ KE + ++ K K + + + + S KL S + + + KS+K I + ++S
Sbjct: 622 LDKEGKVVKKHKTKHKH-KNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLST 680
Query: 920 QEKEKEKEKIPFILEGSLKAWKEEQH----RLAEEERLREEKKAEKKGKEAGK------K 969
+ K K +L+ +K+E+ +L E+E L +++K+ K+ K+ K +
Sbjct: 681 ENKLK-------VLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFR 733
Query: 970 KGKDNAEK-EDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPK 1014
+ KD + K E RSLK+KSP +EK + + + ++ +++ P + E K
Sbjct: 734 EEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKK 779
Score = 40.4 bits (93), Expect = 0.020
Identities = 46/151 (30%), Positives = 74/151 (49%), Gaps = 17/151 (11%)
Query: 861 ITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQ 920
I E + E+K+ K+++ + K +K+ K + K+ KS K I T D
Sbjct: 672 ILLENDLSTENKL--KVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTN-KDI 728
Query: 921 EKEKEKEKIPFILEGSLKAWKEE--QHRLAEEERLR---EEKKAEKKGKEAGKKKGKDNA 975
+ +EK + S KA KE + + +EE+LR EE+K KK K+ K K N
Sbjct: 729 SRSFREEK-----DRSNKAEKERSLKEKSPKEEKLRLYKEERK--KKSKDRPSKLEKKND 781
Query: 976 EKEDSRSLKKKSPYKEKSKEEQVKIQEVTEE 1006
KED S +K+ +KE +E++K ++V E
Sbjct: 782 LKEDKISKEKEKIFKE--DKEKLKKEKVYRE 810
Score = 39.7 bits (91), Expect = 0.033
Identities = 61/315 (19%), Positives = 128/315 (40%), Gaps = 43/315 (13%)
Query: 920 QEKEKEKEKIPFILE---GSLKAWKEEQHRLAEEERLREEKKAEKKGKEA---------- 966
Q E++K+K P G+ A ++++ ++ E+ + +++K++ +K K+
Sbjct: 1171 QHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQ 1230
Query: 967 ---GKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQP---EPKITYPFH 1020
K+K + AEK+ + K KS +KEKS +E K ++ + + + E H
Sbjct: 1231 DKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALH 1290
Query: 1021 GY--NMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVR---------VVKDNH 1069
Y + + +++S ++ + G + F + P K R K+ H
Sbjct: 1291 EYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEKLKEKERH 1350
Query: 1070 NFMIHLND--------PKEIVKKEEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSKFGS 1121
+ KE +K+EKG+ Y +E G + S + E + A+ +
Sbjct: 1351 RHSSSSSKKSHDRERAKKEKAEKKEKGEDY---KEGGSRKDSGQYEKDFLEADAYGVSYN 1407
Query: 1122 FSATLENGICLSISYYGSNGMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKI 1181
A +E+ + +I + + + D + E I L P I + + K + K
Sbjct: 1408 MKADIEDELDKTIELFSTE--KKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKH 1465
Query: 1182 KGKEKPKESLKEEEH 1196
+ K + ++ + H
Sbjct: 1466 REKWRDEKERHRDRH 1480
Score = 33.9 bits (76), Expect = 1.8
Identities = 86/418 (20%), Positives = 160/418 (38%), Gaps = 75/418 (17%)
Query: 637 DNPARFAKQIRQQYVMKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQ 696
+N + K R + K + +K K + K LF D+ ++D + S +
Sbjct: 681 ENKLKVLKHDRDHF--KKEEKLSKMKLEEK---EWLFKDEKSLKRIKDTNKDISRSFREE 735
Query: 697 CDANNMKHSDLNNLKLSVP--DNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADS 754
D +N + +LK P + +L ++E K++ + LE+ N++K+D ++K
Sbjct: 736 KDRSNKAEKE-RSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEK--KNDLKEDKISKE-- 790
Query: 755 HEKKPKKMMVEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQV------------------ 796
K+ + + D E +KK ++ D +F E+ L+
Sbjct: 791 -----KEKIFKEDKEKLKK-EKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSD 844
Query: 797 LQEAHKQYRCVDS-------YYHTQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNY 849
L ++ ++ DS Y + +S+ + + + A R+Y
Sbjct: 845 LSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREK----RDY 900
Query: 850 LE-LVAKSIQDWITKEEAIYQESKMNEKIIR---TRAELELKSSANAKLTSASKIFSIKE 905
E K +D++ K +E K + + + + + SA A + S KE
Sbjct: 901 REPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKE 960
Query: 906 SKSNKGISKTEISDQEKEKE-------KEKIPFILEGSLKAWKEEQHRLAEEERL----- 953
+ G +K E + +E+ KE K+K L+ W E H E+E+
Sbjct: 961 RRD--GRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPW-ERHHPAREKEKKDGPDK 1017
Query: 954 -REEKKAEKKGKEAGKKKGKDNA--------EKEDSRSLKKKSPYKEKSKEEQVKIQE 1002
R+EK ++ KE K K +KE + K+K KEK K+ K +E
Sbjct: 1018 ERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKE 1075
Score = 33.9 bits (76), Expect = 1.8
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 2/108 (1%)
Query: 883 ELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQ-EKEKEKEKIPFILEGSLKAWK 941
E E K + + +K KE S+K S+ I ++ +K+KE +K F + K
Sbjct: 1008 EKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKC-FKEKKDTKEKH 1066
Query: 942 EEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPY 989
++ H +E + ++ EKK K +D +EK+D + K+KS Y
Sbjct: 1067 KDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWY 1114
Score = 32.7 bits (73), Expect = 4.1
Identities = 63/408 (15%), Positives = 155/408 (37%), Gaps = 49/408 (12%)
Query: 636 WDNPARFAKQIRQQYVMKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREP---- 691
WD+P + ++ V K+ + K+ + + +D ++ REP
Sbjct: 858 WDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSR----------AREKRDYREPFFRK 907
Query: 692 SDPSQCDANNMKHSDLNNLKLSVP---DNRQLLEQESIMKAQPQHESLEQTTNNEIKDDA 748
D D N+ K + SVP + +ES + + ++LE E +D
Sbjct: 908 KDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESC--KERRDGR 965
Query: 749 VTKADSHEKKPKKMMVEADLED------------------IKKTQQRSLMDWSFTEHFKP 790
++H ++ K+ E+ +D ++ +++ D E KP
Sbjct: 966 AKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKP 1025
Query: 791 KVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYL 850
+ + + K + + +D F + + H +
Sbjct: 1026 ERYKEKSSDKDKSEKSILEKCQ-KDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGK 1084
Query: 851 ELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNK 910
E K+ I+++ + ++ K ++ A++ S + + + F + E+
Sbjct: 1085 EKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEA---- 1140
Query: 911 GISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKK 970
S +D +EKE+ + + + K+ ++QH ++++ +++ ++ +AG+ K
Sbjct: 1141 --SDLPRTDGLQEKEEGREAYASDRHRKS-SDKQHPERQKDKEPRDRRKDRGAADAGRDK 1197
Query: 971 G----KDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPK 1014
+ + EK+D S +K K+++ + + ++ ++ P + E K
Sbjct: 1198 KEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKK 1245
Score = 32.3 bits (72), Expect = 5.3
Identities = 34/143 (23%), Positives = 62/143 (43%), Gaps = 21/143 (14%)
Query: 885 ELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQ 944
+L A K + K S + KS+K SK S + + EK + + E +L ++E+
Sbjct: 1237 KLPEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDS 1296
Query: 945 HRLAEE-------ERLRE------------EKKAEKKGKEAG--KKKGKDNAEKEDSRSL 983
+ E +R +E E + K +E+ +K K+ S S
Sbjct: 1297 NDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEKLKEKERHRHSSSS 1356
Query: 984 KKKSPYKEKSKEEQVKIQEVTEE 1006
KKS +E++K+E+ + +E E+
Sbjct: 1357 SKKSHDRERAKKEKAEKKEKGED 1379
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 49.7 bits (117), Expect = 3e-05
Identities = 70/322 (21%), Positives = 133/322 (41%), Gaps = 57/322 (17%)
Query: 904 KESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKG 963
K+ K + I +T+++ +EKEK KEK+ + ++ + + +E++ +++K E K
Sbjct: 150 KQEKPERKI-QTKVTHKEKEKGKEKV--------REKEKPEKKATHKEKIEKKEKPETKT 200
Query: 964 KEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYN 1023
+KK K + E+ + K +EK K+ K++EV +++P +P+ K +
Sbjct: 201 LAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEV-QKTPSKPKEKEDKEKAAVS 259
Query: 1024 MGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVK 1083
Q + Y + +F G +K + I P E
Sbjct: 260 KHEQKDQYAFCRYMI------------DIFVHGD-------LKPGQSPAIPPPLPTEQAS 300
Query: 1084 KEEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMA 1143
+ L EE+EG+++++ + S+ K K S
Sbjct: 301 RPTPASPAL-EEKEGEKKKAEKKVTSETKKKEKEDIKKKS-------------------- 339
Query: 1144 PEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLK--EEEHP--KE 1199
+K+ ++ P + T + Q+ AK K + KE K++ K E E P K+
Sbjct: 340 --EKETAIDVEKKEPGKASETKQGTVKIAAQAAAK-KDEKKEDSKKTKKPAEVEQPKGKK 396
Query: 1200 EEKKEEEVEPEPVLQETLDVPT 1221
+EKKE+ VEP ++ VP+
Sbjct: 397 QEKKEKHVEPAKSPKKEHSVPS 418
Score = 40.4 bits (93), Expect = 0.020
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 16/140 (11%)
Query: 886 LKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQH 945
L + ++ T AS KE + K K ++KEKE K E ++ K+E
Sbjct: 294 LPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPG 353
Query: 946 RLAE---------------EERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYK 990
+ +E ++ +E+ K KK E + KGK EK++ KSP K
Sbjct: 354 KASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGK-KQEKKEKHVEPAKSPKK 412
Query: 991 EKSKEEQVKIQEVTEESPHQ 1010
E S +++ TE + +
Sbjct: 413 EHSVPSDKQVKAKTERAKEE 432
Score = 40.0 bits (92), Expect = 0.026
Identities = 96/387 (24%), Positives = 155/387 (40%), Gaps = 83/387 (21%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSI---KESKSNKGISKTEISD 919
K + + + +K ++ + ++K +A AK+ K S KE K +SK E D
Sbjct: 207 KAKTAEKSEEKTKKEVKGGKQEKVKQTA-AKVKEVQKTPSKPKEKEDKEKAAVSKHEQKD 265
Query: 920 QEKEKEKEKIPFILEGSLKAWK----------EEQHRL-----AEEERLREEKKAEKKGK 964
Q + I + G LK + E+ R A EE+ E+KKAEKK
Sbjct: 266 QYAFC-RYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVT 324
Query: 965 EAGKKKGKDN----AEKEDSRSLKKKSPYK-EKSKEEQVKI--QEVTEESPHQPEPKITY 1017
KKK K++ +EKE + ++KK P K ++K+ VKI Q ++ + + K T
Sbjct: 325 SETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKT- 383
Query: 1018 PFHGYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMF-EKGPTFIKVRVVKDNHNFMIHLN 1076
P ++ P Q + EK + K P K H+ +
Sbjct: 384 --------KKPAEVE------QPKGKKQEKKEKHVEPAKSP--------KKEHS----VP 417
Query: 1077 DPKEIVKKEEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISY 1136
K++ K E+ +EE G S++ V K + +K T+E I S
Sbjct: 418 SDKQVKAKTERA-----KEEIG--AVSIKKAVPGKKEEKTTK------TVEQEIRKEKS- 463
Query: 1137 YGSNGMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGK---------EKP 1187
G +DK+P +P++L SKA ++K K EKP
Sbjct: 464 -GKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKP 522
Query: 1188 KESLKEEEHPKEEEK----KEEEVEPE 1210
+ +K+E P EK K++ V+PE
Sbjct: 523 EPQIKKEAKPAISEKVQIHKQDIVKPE 549
Score = 34.3 bits (77), Expect = 1.4
Identities = 44/187 (23%), Positives = 74/187 (39%), Gaps = 31/187 (16%)
Query: 851 ELVAKSIQDWITKEEAIYQESKMN---------EKIIRTRAELELKSSANAKLTSASKIF 901
E K+++ I KE++ S + EK+ + E E ++ + K++ A K
Sbjct: 448 EKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEV 507
Query: 902 SIKESK-SNKGISKTE--ISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLRE--- 955
K + K K E I + K EK+ + +K K H EE+ L++
Sbjct: 508 KPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKA 567
Query: 956 -----------EKKAEKKGKE-----AGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVK 999
KKAE + +E K K E + S KKK+ EK +E+
Sbjct: 568 VTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKAD 627
Query: 1000 IQEVTEE 1006
++ + EE
Sbjct: 628 MKHLREE 634
Score = 33.1 bits (74), Expect = 3.1
Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 23/163 (14%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANA----KLTSASKIFSIKESKSNKGISKTEIS 918
KE ++ + ++ K R + E+ S A K +K + K G + + +
Sbjct: 412 KEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILK 471
Query: 919 DQEKEKEKE-KIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEK 977
D+E K KE K+P SLK +E ++++K K GKE K + +K
Sbjct: 472 DKEPIKGKEEKVP----ASLKE---------KEPETKKDEKMSKAGKEVKPKPPQLQGKK 518
Query: 978 EDSRSLK-KKSPYKEKSKEEQVKIQEVTEE----SPHQPEPKI 1015
E+ + KK S++ Q+ Q++ + S +PE K+
Sbjct: 519 EEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKV 561
Score = 32.3 bits (72), Expect = 5.3
Identities = 17/62 (27%), Positives = 28/62 (45%)
Query: 139 KDQQRRENEKKVIEDKPKLEKDKGKAKSPKEKKAPSAKPAKGKGKDQPEANAPVKKTTQL 198
K+ ++++ EKKV + K EK+ K KS KE K GK + + +
Sbjct: 312 KEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAA 371
Query: 199 KR 200
K+
Sbjct: 372 KK 373
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 49.3 bits (116), Expect = 4e-05
Identities = 77/386 (19%), Positives = 165/386 (42%), Gaps = 43/386 (11%)
Query: 645 QIRQQYVMKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPS-QCDANNMK 703
Q QQ + Q+ +Q D K ++ ++ L ++ + +R+ D + + ++
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFRE-----EEQLRQEREEQQLSRQERDRKFRLEEQKVR 1589
Query: 704 HSDLNNLKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKK----- 758
+ R+ +E E ++ Q + L Q + + ++D + E++
Sbjct: 1590 RQE---------QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Query: 759 --PKKMMVEADLEDIKKTQQ-RSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQD 815
K + E L ++ QQ R D F E + LLQ +E + + D + ++
Sbjct: 1641 RDRKFLEEEPQLRRQEREQQLRHDRDRKFREE---EQLLQEGEEQQLRRQERDRKFREEE 1697
Query: 816 NSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEA---IYQESK 872
L R+ L E FR +L ++ Q+ + ++E I +E +
Sbjct: 1698 QQLR---RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754
Query: 873 MN----EKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEK 928
+ E+ +R R E + K +L + ++ +S++ + E QE+E+++ +
Sbjct: 1755 LRPEREEQQLR-RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLR 1813
Query: 929 IPFILEGSLKAWKEEQHRLAEEE-RLREEKKAEKKGKEAGKKKGKDNAEKED---SRSLK 984
P +G + W+EEQ +L E+E RLR+E+ + + +E + K E+++ K
Sbjct: 1814 -PQQRDGKYR-WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQK 1871
Query: 985 KKSPYKEKSKEEQVKIQEVTEESPHQ 1010
++ + K +EE ++ Q+ E+ Q
Sbjct: 1872 RRQERERKLREEHIRRQQKEEQRHRQ 1897
Score = 41.6 bits (96), Expect = 0.009
Identities = 28/149 (18%), Positives = 77/149 (51%), Gaps = 6/149 (4%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSN-KGISKTEISDQE 921
+++ ++QE + EK R R + K + + ++E + + + + E+ +
Sbjct: 233 RQDRVFQEEE--EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
Query: 922 KEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSR 981
+E+E+++ E L+ +EE+ R +EER ++++ E++ + +++ + E+E+ R
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE---RREQQLRREQEERR 347
Query: 982 SLKKKSPYKEKSKEEQVKIQEVTEESPHQ 1010
+ + +E+ +E+Q++ ++ E Q
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQ 376
Score = 40.4 bits (93), Expect = 0.020
Identities = 33/147 (22%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Query: 869 QESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEK 928
QE + ++K R +LE + A + K + + + E Q +E+EK +
Sbjct: 866 QEQRRDQK---WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922
Query: 929 IPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSP 988
+ + ++EE+ EEE+L E++ +++ +E ++ KD ++ L + P
Sbjct: 923 ----RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP 978
Query: 989 YKEKSKEEQVKIQEVTEESPHQPEPKI 1015
K + +E + K +E EE Q E ++
Sbjct: 979 EKRRRQEREKKYRE--EEELQQEEEQL 1003
Score = 39.3 bits (90), Expect = 0.044
Identities = 56/359 (15%), Positives = 142/359 (39%), Gaps = 13/359 (3%)
Query: 654 MNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLKLS 713
+ +E K + + + R L ++ ++ E RE + Q + L +
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 714 VPDNRQLLEQESIMKAQPQHESLEQTTNNEIKD--DAVTKADSHEKKPKKMMVEADLEDI 771
+Q +E + + Q E EQ E ++ + + + E++ ++ + E+
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
Query: 772 KKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRL 831
++ Q R + + + L+ Q+ ++ + ++ L +R
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL----RREQQLRRE 428
Query: 832 HCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSAN 891
E + H L+ + +DW+ +EE + + K R + E +
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 892 AKLTSASKIFSIKESKSNKGISKTEISDQ--EKEKEKEKIPFILEGSLKAWKEEQHRLAE 949
KL + + + + E +Q ++++E+E++ L + +E++ R +
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 950 EERLREEKKAEKKGKEAGKKKGKDN-----AEKEDSRSLKKKSPYKEKSKEEQVKIQEV 1003
+ EEK+ E++ +E K+ ++ ++E+ R ++ +E+ E+++K +EV
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV 607
Score = 39.3 bits (90), Expect = 0.044
Identities = 71/384 (18%), Positives = 153/384 (39%), Gaps = 39/384 (10%)
Query: 647 RQQYVMKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNRE----PSDPSQCDANNM 702
R+ + + +E ++ ++ R +Q + RE P + +
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
Query: 703 KHSDLNNLKLSVPDNRQLLEQESIMKAQPQHESL----EQTTNNEIKDDAVTKADSHEKK 758
+ L+ + + QL +E + Q + + L E+ + E + D + E++
Sbjct: 824 RREREKELQF-LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER 882
Query: 759 PKKMMV----EADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQ 814
++ A E ++K QQ L+ E + + + QE +QYR + +
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQ--LLQEEEEELQREEREKRRRQEQERQYR-EEEQLQQE 939
Query: 815 DNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMN 874
+ LL RQ +Y R +L K Q + EE + +
Sbjct: 940 EEQLLREEREKRRRQERERQY-----------RKDKKLQQKEEQ--LLGEEPEKRRRQER 986
Query: 875 EKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKE---KEKEKIPF 931
EK R EL+ + +L + ++ + K E+ +E++ +E+EK
Sbjct: 987 EKKYREEEELQQEEE---QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR- 1042
Query: 932 ILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKE 991
L+ + ++EE+ EEE+L E++ ++ +E ++ K+ +++ L ++ P K
Sbjct: 1043 -LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Query: 992 KSKEEQVKIQEVTEESPHQPEPKI 1015
+ +E + + +E EE Q E ++
Sbjct: 1102 RRQERERQCRE--EEELQQEEEQL 1123
Score = 38.9 bits (89), Expect = 0.057
Identities = 67/396 (16%), Positives = 149/396 (37%), Gaps = 26/396 (6%)
Query: 645 QIRQQYVMKMNTQEAKQKADIKI-KDRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMK 703
Q+ ++ + +T AK ++ K++ L ++ + ++ E R Q
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 704 HSDLNNLKLSVPDNRQLLEQE-SIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKM 762
+ L + R+ E+E K + + EQ E + + + ++ +++
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 763 MVEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQV--------------LQEAHKQYRCVD 808
E + ++ ++R +W ++ K LQ LQE +QYR +
Sbjct: 997 QQEEEQLLREEREKRRRQEWE--RQYRKKDELQQEEEQLLREEREKRRLQERERQYR-EE 1053
Query: 809 SYYHTQDNSLLLVFHNPMNRQRLHCEYWN---IALHSNVGFRNYLELVAKSIQDWITKEE 865
++ LL RQ L +Y + R E + ++ +EE
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE 1113
Query: 866 AIYQESK----MNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQE 921
Q+ + E+ R R ELE + ++ + +E + + +E
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE 1173
Query: 922 KEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSR 981
+E ++E+ + E K +E + + EEE L+ +K+ ++ E + K E E
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKEN 1233
Query: 982 SLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITY 1017
+++ Y + + EQ + E ++ Q + + +
Sbjct: 1234 AVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH 1269
Score = 38.5 bits (88), Expect = 0.074
Identities = 25/108 (23%), Positives = 57/108 (52%), Gaps = 15/108 (13%)
Query: 903 IKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLR--EEKKAE 960
+++ +S + + QE+++E+E+ + W++ EEE+L E+K+A+
Sbjct: 1258 LRDRQSQQDLQHLLGEQQERDREQER---------RRWQQRDRHFPEEEQLEREEQKEAK 1308
Query: 961 KKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESP 1008
++ +++ ++K E+E+ R ++ K +EE+ +QE EE P
Sbjct: 1309 RRDRKSQEEKQLLREEREEKR---RRQETDRKFREEEQLLQE-REEQP 1352
Score = 38.1 bits (87), Expect = 0.097
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 37/172 (21%)
Query: 858 QDWITKEEAIYQESKM------------NEKIIRTRAELELKSSANAKLTSASKIFSIKE 905
Q+W +EE +E ++ +E+ +R R LEL+ +E
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGR------------EE 225
Query: 906 SKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEE-----RLREEKKAE 960
+ + + + +E+EKE K +L ++E+ +L EEE L+EE++
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVL-------RKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 961 KKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPE 1012
+K + ++ + E++ R L+++ + K +EE+ + QE E + E
Sbjct: 279 RKLERQELRRERQEEEQQQQR-LRREQQLRRKQEEERREQQEERREQQERRE 329
Score = 35.0 bits (79), Expect = 0.82
Identities = 26/123 (21%), Positives = 62/123 (50%), Gaps = 12/123 (9%)
Query: 904 KESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEK------ 957
+E + +G ++E ++ +++++++ L + W+E + R AEEE+L+ K
Sbjct: 144 QERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE 203
Query: 958 ---KAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEV---TEESPHQP 1011
+ + + +E + + K EK+ R ++ ++E+ ++E K + V EE +
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEE 263
Query: 1012 EPK 1014
EP+
Sbjct: 264 EPQ 266
Score = 35.0 bits (79), Expect = 0.82
Identities = 62/370 (16%), Positives = 147/370 (39%), Gaps = 67/370 (18%)
Query: 648 QQYVMKMNTQEAKQKADIKIK----DRTLFVDQNLSMSVQDNESNREPSDPSQCDANNMK 703
Q+ K ++ Q++D+K + D + ++NE R+ D D + +
Sbjct: 1206 QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQ 1265
Query: 704 HSDLNNLKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMM 763
DL +L L R ++ + + +H E+ E + +A K + + +K +
Sbjct: 1266 --DLQHL-LGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEA--KRRDRKSQEEKQL 1320
Query: 764 VEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFH 823
+ + E+ ++ Q+ D F E Q+LQE +Q
Sbjct: 1321 LREEREEKRRRQET---DRKFREEE------QLLQEREEQ-------------------- 1351
Query: 824 NPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAE 883
P+ RQ ++ L R +LE EE + + K ++ +
Sbjct: 1352 -PLRRQERDRKFREEELRHQEQGRKFLE------------EEQRLRRQERERKFLKEEQQ 1398
Query: 884 LELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEE 943
L + + F +E + +S+ E + +E+E++ ++ + E
Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQ----LSRQERDRKFREEEQQ---------VRRQERE 1445
Query: 944 QHRLAEEERLREEKKAEKKGKE---AGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKI 1000
+ L EE++LR+E+ + + +E +++ + + ++ D + L+++ + + ++ + +
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
Query: 1001 QEVTEESPHQ 1010
QE+ + P +
Sbjct: 1506 QELRSQEPER 1515
Score = 34.3 bits (77), Expect = 1.4
Identities = 61/402 (15%), Positives = 157/402 (39%), Gaps = 50/402 (12%)
Query: 722 EQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQ----QR 777
EQE ++ + + E +E+ E ++ + + + E++ ++++ + E+ ++ Q Q+
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 778 SLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWN 837
+ + + L Q L+ H++ R + R + W
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA-------RERIKSRIPKWQ 705
Query: 838 IALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSA 897
L S R + K+E + + EK R +EL+ + A
Sbjct: 706 WQLESEADARQ------SKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ- 758
Query: 898 SKIFSIKESKSNKGISKTEISDQEKEKEKEKI---PFILEGSLKAWKEEQHRLAEEERLR 954
+E + + + ++++ E+ ++++ P + E + + E+ + E+ L
Sbjct: 759 ------QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLP 812
Query: 955 EEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQ--VKIQEVTEESPHQPE 1012
EE++ E++ ++ +++ K+ E+ L+++ ++ +EE + QE + +
Sbjct: 813 EEEEKEQRRRQR-REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD 871
Query: 1013 PKITYPFHGYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFM 1072
K + T Y P+ Q+ E+ + ++ ++
Sbjct: 872 QKWRWQLEEERKRRRHT------LYAKPALQEQLRKEQQLLQEEEEELQ----------- 914
Query: 1073 IHLNDPKEIVKKEEKGDYYLEEEEEGDEEQSLETEVSDAKNK 1114
+ +E +++E+ Y EEE+ EE+ L E + + +
Sbjct: 915 ---REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR 953
Score = 33.9 bits (76), Expect = 1.8
Identities = 70/424 (16%), Positives = 171/424 (40%), Gaps = 57/424 (13%)
Query: 636 WDNPARFAKQIRQQYVMKMNTQEAKQKADIKIKDRTLFVD-QNLSMSVQDNESNREPSDP 694
W+ A + + Y ++ +Q D +++DR D Q+L Q+ + +E
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW 1286
Query: 695 SQCDANNMKHSDLNN--LKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKA 752
Q D + + L K + +R+ E++ +++ + + + Q T+ + +++
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346
Query: 753 DSHEKKPKKMMVEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYH 812
+ E+ ++ E +K ++ L F + QE +++ +
Sbjct: 1347 EREEQPLRRQ------ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
Query: 813 TQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQD--WITKEEAIYQE 870
Q+ L +R+ E + FR + V + ++ ++ +E+ + QE
Sbjct: 1401 CQEREQQL--RQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
Query: 871 S----KMNEKIIRTRAELEL-KSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEK- 924
+ E++++ R E +L + + K + ++ + ++ + E+ QE E+
Sbjct: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ--QLRRQERDRKFREQELRSQEPERK 1516
Query: 925 --EKEKIPFILEGSLKAWKEEQH----------------RLAEEERLREEKKAEKKGKEA 966
E+E+ + K +EEQ + EEE+LR+E++ ++ ++
Sbjct: 1517 FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Query: 967 GKKKGKDNAEK-----------EDSRSLKKKSPYKE-------KSKEEQVKIQEVTEESP 1008
+K + +K ED + L+++ ++ K +E++ +QE E+
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQL 1636
Query: 1009 HQPE 1012
H+ E
Sbjct: 1637 HRQE 1640
Score = 32.3 bits (72), Expect = 5.3
Identities = 29/150 (19%), Positives = 75/150 (50%), Gaps = 14/150 (9%)
Query: 863 KEEAIYQESKMNEKIIRT---RAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISD 919
+EE + Q + +++ R R E LK +L + +K + + + ++
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEER---RDQLLK 580
Query: 920 QEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGK----EAGKKKGKDNA 975
+E+E+ ++++ E L E++ + E ERL +E++ E++ K E +++ +
Sbjct: 581 REEERRQQRLKREQEERL----EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636
Query: 976 EKEDSRSLKKKSPYKEKSKEEQVKIQEVTE 1005
E+++ R ++ +++ +E+++K +E E
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEE 666
Score = 32.0 bits (71), Expect = 7.0
Identities = 51/304 (16%), Positives = 122/304 (40%), Gaps = 30/304 (9%)
Query: 719 QLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDIKKTQQRS 778
Q L +E ++ + + E EQ E ++ + + + K E + + ++ +Q+
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476
Query: 779 LMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNI 838
D E + + L+ + +Q R Q+ QRL +
Sbjct: 477 KRDQE-EERRERWLKLEEEERREQQERREQQLRREQEER---------REQRLKRQEEEE 526
Query: 839 ALHSNVGFRNYLELVAKSIQDWITK--EEAIYQESKMNEKIIRTRAELELKSSANAKLTS 896
L + L + ++ + K EE ++ + +++ R + E + +
Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 897 ASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRL-----AEEE 951
++ +E + + + + E+ E+E+ +E+ LK + E+ R +EE+
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQ-------RLKREEPEEERRQQLLKSEEQ 639
Query: 952 RLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQP 1011
R +++ ++ +E +++ K E+E+ + K ++E+ +E QE+ EE Q
Sbjct: 640 EERRQQQLRREQQERREQRLK-REEEEERLEQRLKREHEEERRE-----QELAEEEQEQA 693
Query: 1012 EPKI 1015
+I
Sbjct: 694 RERI 697
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 48.9 bits (115), Expect = 5e-05
Identities = 71/373 (19%), Positives = 162/373 (43%), Gaps = 40/373 (10%)
Query: 656 TQEAKQKADIKIKDRTLFVDQNLS---MSVQDNESNRE------PSDPSQCDANNMK--- 703
T E ++ + K++++ V+ S ++V++ + E P Q +A+++
Sbjct: 203 TDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 262
Query: 704 HSDLNNLKLSVPDNR--QLLEQESIMKAQPQHESLEQTTNN-EIKDDAVTKADSHEKKPK 760
S L+ V +N L Q+ K Q E +++ + +++ + + + ++ +
Sbjct: 263 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQE 322
Query: 761 KMMVEADLEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLL 820
+MM E + +K +++ M W K + + ++ ++ H+Q + + Q+ +
Sbjct: 323 EMMWEKE----EKMRRQEEMMWE-----KEEKIRELEEKMHEQEKIREQEEKRQEEEKI- 372
Query: 821 VFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAI-YQESKMNEKIIR 879
RQ + W R E + + + +EE + QE KM E+
Sbjct: 373 --REQEKRQEQEAKMWR----QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE 426
Query: 880 TRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKA 939
+ + E K+ K +E K + + E+ +++EK E+ + E K
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIRE---QEEMMQEQEEKMGEQEGKMCEQEAKM 483
Query: 940 WKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVK 999
++E+ +EE++RE++K ++ +E +++ + E+E+ K +EK E++ K
Sbjct: 484 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE-----KMWEQEEKMCEQEEK 538
Query: 1000 IQEVTEESPHQPE 1012
+QE E+ Q E
Sbjct: 539 MQEQEEKMRRQEE 551
Score = 45.1 bits (105), Expect = 8e-04
Identities = 46/177 (25%), Positives = 83/177 (46%), Gaps = 24/177 (13%)
Query: 863 KEEAIY-QESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESK----SNKGISKTEI 917
+EE I QE K+ E+ + R + E+ K+ ++ KE K K + +I
Sbjct: 300 REEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 359
Query: 918 SDQE-KEKEKEKI---PFILEGSLKAWKEEQHRLAEEERLREEKKA-----EKKGKEAGK 968
+QE K +E+EKI E K W++E+ +EE++RE+++ EK G++ K
Sbjct: 360 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 419
Query: 969 ----------KKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKI 1015
++ K ++E R +KK +E+ EQ ++ + EE + E K+
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKM 476
Score = 35.0 bits (79), Expect = 0.82
Identities = 41/238 (17%), Positives = 106/238 (44%), Gaps = 15/238 (6%)
Query: 782 WSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALH 841
W F + + L V + K R ++ +D L ++ N + + L + N L
Sbjct: 159 WKFAGELE-QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK--NAKLQ 215
Query: 842 SNVGF----RNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSA 897
+ ++ ++L K ++ + + + + + ++ + EL+ S+
Sbjct: 216 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 275
Query: 898 SKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEK 957
+++++ + + + + E QE+E++ I E K ++E+ +EE + E++
Sbjct: 276 NELWNRLNQQQEEKMWRQEEKIQEREEK------IQEQEEKIREQEEKMRRQEEMMWEKE 329
Query: 958 KAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKI 1015
+ ++ +E +K + E E+ ++K +E+ ++E+ KI+E +E + E K+
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE--QEKRQEQEAKM 385
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 48.5 bits (114), Expect = 7e-05
Identities = 68/304 (22%), Positives = 130/304 (42%), Gaps = 26/304 (8%)
Query: 721 LEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLEDI-------KK 773
LE + I KA + +++ T NNE + + K +K K+ + D E++ KK
Sbjct: 67 LEAQGI-KADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKK 125
Query: 774 TQQRSLMDWSFTE-----HFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNR 828
T + + +S ++ + PK Q+++K++ D +DNS + + +N
Sbjct: 126 TAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKW---DGSEEDEDNSKKIKERSRINS 182
Query: 829 QRLHCEYWNIALHSNVGFR-NYLELVAKSIQDWITKEEAIYQ-ESKMNEKIIRTRAELEL 886
+ + L S G + N +I+ ++A ++ ++ +K + E +
Sbjct: 183 SGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKK 242
Query: 887 KSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHR 946
+ AKL + ++ K ++ K E+E K K+ + G + A +E+
Sbjct: 243 RDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVT-VDTGVIPASEEKAET 301
Query: 947 LAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEE 1006
E ++ + +KK K+ KKKG EKE+ KKK P K K Q + ++ EE
Sbjct: 302 PTAAE---DDNEGDKKKKDKKKKKG----EKEEKEKEKKKGPSKATVKAMQEALAKLKEE 354
Query: 1007 SPHQ 1010
Q
Sbjct: 355 EERQ 358
Score = 48.1 bits (113), Expect = 9e-05
Identities = 100/447 (22%), Positives = 166/447 (37%), Gaps = 69/447 (15%)
Query: 863 KEEAIYQES--KMNEKIIRTRAELE---LKSSANAKLTSASKIFSIKESKSNKGISKTEI 917
K+++ +ES K E+ ++++ ++ + +S T + + K K K +
Sbjct: 264 KDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKG 323
Query: 918 SDQEKEKEKEKIPF-----ILEGSLKAWKEEQHRLA--EEERLR-----EEKKAEKKGKE 965
+EKEKEK+K P ++ +L KEE+ R EEER++ E K+ E++ E
Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE 383
Query: 966 AGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVT---------EESPHQPEPKIT 1016
K++ K EKE LKK+ KS+ E E T E PK
Sbjct: 384 QEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKR 443
Query: 1017 YPFHGYNMGNIPTQISGSNYYLYPSDGGQIEV-EKTMFEKGPTFIKVRVVKDNHNFMIHL 1075
+ IP Q+ +EV E+ + EK T V ++ L
Sbjct: 444 PIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGL 503
Query: 1076 ND-------------------------PKEIVKKEEKGDYYLEEEEEGDEEQSLETEVSD 1110
+D P+E ++EE+ + E EEE +EE E D
Sbjct: 504 DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGD 563
Query: 1111 AKNKAFSKFGSFSATLENGICLSIS----YYGSNGMAPEDKDPD----------LETILN 1156
+++ S TL+ +S Y + E++ D LE N
Sbjct: 564 EEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKN 623
Query: 1157 I-PSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPEPVLQE 1215
+ L ++ V+ V K KI K + E ++ V E + ++
Sbjct: 624 VNTEKLRAPIICVLGHVDTGKT--KILDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQ 681
Query: 1216 TLDVPTFQSLNVSCPSGLLLTFIGQES 1242
T + F NV P L++ G ES
Sbjct: 682 TKMIKNFDRENVRIPGMLIIDTPGHES 708
Score = 37.0 bits (84), Expect = 0.22
Identities = 63/293 (21%), Positives = 111/293 (37%), Gaps = 57/293 (19%)
Query: 865 EAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEK 924
E + + ++K + + E+ S + K K KSNK +E + +K
Sbjct: 114 EELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKK 173
Query: 925 EKEKIPFILEG-----------SLKAWKEEQHRLA----------EEERLREEKKAEKKG 963
KE+ G S K K+ Q ++ + + A+KK
Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKA 233
Query: 964 KEAGKKKGKDNAEKEDSRSLKKKSPY------KEKSKEEQVKIQEVTEESPHQPEPKITY 1017
++ +++ K + EK R LK+K + K KE Q K +E T +S K+T
Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKS------KVT- 286
Query: 1018 PFHGYNMGNIPTQISGSNYYLYPSDG--------------GQIEVEKTMFEKGPTFIKVR 1063
+ G IP + D G+ E ++ +KGP+ V+
Sbjct: 287 ----VDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVK 342
Query: 1064 VVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEEEEG--DEEQSLETEVSDAKNK 1114
+++ + L + +E K+EE+ EE E EE+ LE E + K +
Sbjct: 343 AMQE---ALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQ 392
Score = 33.5 bits (75), Expect = 2.4
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 156 KLEKDKGKAKSPKEKKAPSAK--PAKGKGKDQPEANAPVKKTTQLKRRGEDDHTNR 209
K +KDK K K KE+K K P+K K EA A +K+ + ++R E++ R
Sbjct: 313 KKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKR 368
Score = 33.1 bits (74), Expect = 3.1
Identities = 83/350 (23%), Positives = 139/350 (39%), Gaps = 68/350 (19%)
Query: 882 AELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWK 941
AE+E +A + SK KE K K + + + KE E++ +G +KA +
Sbjct: 24 AEIEGAGAAKEQEPQKSKGKKKKEKK------KQDFDEDDILKELEELSLEAQG-IKADR 76
Query: 942 E----EQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKE----DSRSLK--------- 984
E + EEE ++KK KKG++ K+ DN +E DS+S K
Sbjct: 77 ETVAVKPTENNEEEFTSKDKK--KKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMY 134
Query: 985 ---------KKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSN 1035
K P K K K ++ + E KI + G + S+
Sbjct: 135 SGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDE---SD 191
Query: 1036 YYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEE 1095
+L S GQ + +K + GP I+ D+ +F I K+ KKE + EE+
Sbjct: 192 EFLQ-SRKGQKKNQKN--KPGPN-IESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEK 247
Query: 1096 ---EEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAPEDKDPDLE 1152
+ E++ LET D + S+ T+++ + + G+ P ++
Sbjct: 248 AKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVD------TGVIPASEE---- 297
Query: 1153 TILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEK 1202
A TPT + +G K K+K K+ ++EE KE++K
Sbjct: 298 ------KAETPTAA-------EDDNEGDKKKKDKKKKKGEKEEKEKEKKK 334
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 48.1 bits (113), Expect = 9e-05
Identities = 43/159 (27%), Positives = 74/159 (46%), Gaps = 7/159 (4%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEK 922
+E +E + EK R R + + + K + K + E ++EK
Sbjct: 55 RESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEK 114
Query: 923 EKEKEKIP---FILEGSLKAWKEEQHRLAEEERLREEKKAEK--KGKEAGKKKGKDNAEK 977
K+KEK EG + KEE+ R +ER R++++ EK + KE K++ K EK
Sbjct: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK 174
Query: 978 EDSRSLKKKSPYK--EKSKEEQVKIQEVTEESPHQPEPK 1014
E+ R K++ K E++++E+ K +E E + E K
Sbjct: 175 EEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
Score = 48.1 bits (113), Expect = 9e-05
Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 13/142 (9%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAK----LTSASKIFSIKESKSNKGISKTEIS 918
K+E ++ + EK + E E + K + K KE + + + E
Sbjct: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
Query: 919 DQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEK-KAEKKGKEAGKKKGKDNAEK 977
+E+EKE+E+ + K E+ ++ E+E R+EK + E+K +E +K+ K E+
Sbjct: 151 KEEREKERER--------KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
Query: 978 EDSRSLKKKSPYKEKSKEEQVK 999
++ R KK+ KE+ K+E+ K
Sbjct: 203 KERRERKKERKKKEERKKERQK 224
Score = 42.4 bits (98), Expect = 0.005
Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 6/86 (6%)
Query: 914 KTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKD 973
++EI ++E+E E K EG + E + E E+ + E++ E+K +E GKK+ K
Sbjct: 35 QSEIREREREIETRK-----EGKKERESERKKERREREKRKREREKERK-RERGKKEKKG 88
Query: 974 NAEKEDSRSLKKKSPYKEKSKEEQVK 999
+KE+ K++ + K EE+ K
Sbjct: 89 ERKKEERERKKRRREKENKEGEEKEK 114
Score = 41.6 bits (96), Expect = 0.009
Identities = 33/139 (23%), Positives = 67/139 (48%), Gaps = 11/139 (7%)
Query: 878 IRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSL 937
++ EL++ S ++ + + + + I + +E+E E++K
Sbjct: 11 VKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKK--------E 62
Query: 938 KAWKEEQHRLAEEERLREEKKAEKKG--KEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKE 995
+ +E++ R E+ER RE K EKKG K+ +++ K EKE+ ++K K+K K+
Sbjct: 63 RREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEG-EEKEKRKKKEKK 121
Query: 996 EQVKIQEVTEESPHQPEPK 1014
E+ + + +E + E K
Sbjct: 122 ERGRTSKEGKERERKEERK 140
Score = 40.8 bits (94), Expect = 0.015
Identities = 33/124 (26%), Positives = 57/124 (45%), Gaps = 12/124 (9%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEK 922
KE +E K E+ R R + E + K ++ + K + + E +EK
Sbjct: 131 KERERKEERKREERKERERKKEEREKERERKE---------RKKRERKQVGEKEEERKEK 181
Query: 923 EKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRS 982
E+++ K E + K K+E+ R ER +E KK E++ KE K + + EKE +
Sbjct: 182 ERKERKKR---ERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKR 238
Query: 983 LKKK 986
+K+
Sbjct: 239 ERKE 242
Score = 39.7 bits (91), Expect = 0.033
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 13/158 (8%)
Query: 870 ESKMNEKIIRTRAE--LELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKE 927
E + E+ I TR E E +S + K +E + + K E + K++E+E
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 928 KIPFILEGSLKAWKEEQHRLAEEERLR--------EEKKAEKKGKEAGKKKGKDNAEKED 979
+ E K +E++ R +E++ R E ++ E++ +E K++ + E+E
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 980 SRSLKKKSPYKEK---SKEEQVKIQEVTEESPHQPEPK 1014
R K++ + K KEE+ K +E E + K
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK 194
Score = 37.0 bits (84), Expect = 0.22
Identities = 31/132 (23%), Positives = 57/132 (43%), Gaps = 3/132 (2%)
Query: 863 KEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEK 922
KE ++ K EK R R E K + K KE + K + E +E+
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKE---ERKREERKERERKKEEREKERERKER 163
Query: 923 EKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRS 982
+K + K E K + ++ + E R +K+ E+K + KK+ K E++ R
Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQ 223
Query: 983 LKKKSPYKEKSK 994
+++ ++EK +
Sbjct: 224 KDRQTNWREKER 235
Score = 36.2 bits (82), Expect = 0.37
Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query: 904 KESKSNKGISKTEISDQEKE-KEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKK 962
+E K K + ++ ++E+E KEKE+ E + ++ + E + R E+K E+K
Sbjct: 158 RERKERKKRERKQVGEKEEERKEKER----KERKKRERNRKERKKERERKERRERKKERK 213
Query: 963 GKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSK 994
KE KK+ + + + + K KE+ K
Sbjct: 214 KKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 48.1 bits (113), Expect = 9e-05
Identities = 45/182 (24%), Positives = 85/182 (46%), Gaps = 30/182 (16%)
Query: 841 HSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTR------AELELKSSANAKL 894
H V RN ++ ++ +D +E + +E +E R R AELE ++ + K
Sbjct: 1325 HKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE-ENQRSYKQ 1383
Query: 895 TSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLR 954
+ ++E S++ S +E ++EKE+E+E EE+ EEE
Sbjct: 1384 KKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEE--------------EEEEEEEEEEDEN 1429
Query: 955 EEKKAEKKGKEAGKKKGKD--------NAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEE 1006
++ K+ KG++ +K KD NA KE+ +K+ +E+ +E+ ++ E+ +
Sbjct: 1430 DDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEER-RKRIAEREREREKLREVIEIEDA 1488
Query: 1007 SP 1008
SP
Sbjct: 1489 SP 1490
Score = 37.7 bits (86), Expect = 0.13
Identities = 23/105 (21%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 904 KESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRL--AEEERLREEKKAEK 961
KE K KG ++ ++S ++ E + + E ++ E++ R A++ L E +++ K
Sbjct: 1323 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1382
Query: 962 KGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEE 1006
+ K+ + K ++++ E+ + +++ KE+ +EE+ + +E E+
Sbjct: 1383 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1427
Score = 37.0 bits (84), Expect = 0.22
Identities = 31/143 (21%), Positives = 65/143 (45%), Gaps = 19/143 (13%)
Query: 875 EKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILE 934
EK + + E+K K++S E + ++ +S++ E E E+ P
Sbjct: 1317 EKKTKPKEHKEVKGRNRRKVSS--------EDSEDSDFQESGVSEEVSESEDEQRP---- 1364
Query: 935 GSLKAWKEEQHRLAEEERLREEKKAEK--KGKEAGKKKGKDNAEKEDSRSLKKKSPYKEK 992
+ ++ L E +R ++KK + K +E + K N+E+E+ K++ +E+
Sbjct: 1365 ---RTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEE--KEEEEEEEE 1419
Query: 993 SKEEQVKIQEVTEESPHQPEPKI 1015
+EE+ + + +SP + KI
Sbjct: 1420 EEEEEEEDENDDSKSPGKGRKKI 1442
Score = 35.8 bits (81), Expect = 0.48
Identities = 99/499 (19%), Positives = 182/499 (36%), Gaps = 81/499 (16%)
Query: 642 FAKQIRQQYVMKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANN 701
F K I+Q +K T + ++K+ KI+D+T LS + + + CD++
Sbjct: 990 FPKGIKQ---IKNGTTDGEKKSK-KIRDKTSKKKDELS-----DYAEKSTGKGDSCDSSE 1040
Query: 702 MKHSDLNNLKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKAD-------- 753
K S N R L +S K Q S T +K+D +D
Sbjct: 1041 DKKS--KNGAYGREKKRCKLLGKSSRKRQDCSSS--DTEKYSMKEDGCNSSDKRLKRIEL 1096
Query: 754 ------SHEKKPKKMM-------VEADLEDIKKTQQR-SLMDWSFTEHFKPKVLLQVLQE 799
S ++ K++ E ED KK +QR S + K + L+ +
Sbjct: 1097 RERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTK 1156
Query: 800 AHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYL--ELVAKSI 857
+ S +D+ + + Q++ N+ L S+ GF E ++KS+
Sbjct: 1157 RKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSV 1216
Query: 858 QDWITKEEAIYQ-ESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTE 916
+ ++ E+++ +K++ + L S + + E K G E
Sbjct: 1217 PVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPE-----EGKKRTGKQNEE 1271
Query: 917 ISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAE 976
E+ K + + + EE + RL K G+ +KK K
Sbjct: 1272 NPGDEEAKNQ------VNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEH 1325
Query: 977 KEDSRSLKKK--SPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGS 1034
KE ++K S E S ++ + E ES + P+
Sbjct: 1326 KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR------------------ 1367
Query: 1035 NYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEE 1094
+ ++E + +++ +++V +D+ + N +E +KEE EE
Sbjct: 1368 -----SAKKAELEENQRSYKQKKKRRRIKVQEDSSSEN-KSNSEEEEEEKEE------EE 1415
Query: 1095 EEEGDEEQSLETEVSDAKN 1113
EEE +EE+ E E D+K+
Sbjct: 1416 EEEEEEEEEEEDENDDSKS 1434
Score = 33.9 bits (76), Expect = 1.8
Identities = 82/391 (20%), Positives = 143/391 (36%), Gaps = 63/391 (16%)
Query: 879 RTRAELELKSSANAKLTSASKI--FSIKE---SKSNKGISKTEISDQEKEKEKEKIPFIL 933
+ R +L KSS + S+S +S+KE + S+K + + E+ ++ K I
Sbjct: 1053 KKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQ 1112
Query: 934 EGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKK-------- 985
GS + EE +E+ + ++++ + KK K+K +++ R
Sbjct: 1113 SGSSSSDAEES---SEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSD 1169
Query: 986 -----KSPYKEKSKEEQVKIQEVTEE---SPHQP----------EPKITYPFHGYNMGNI 1027
++ E S +EQ KI+ VTE S H + + N
Sbjct: 1170 IEDDDQNSIGEGSSDEQ-KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDND 1228
Query: 1028 PTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHN------FMIHLNDPKEI 1081
P L E + P K R K N +N +
Sbjct: 1229 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS 1288
Query: 1082 VKKEEKGDYY----------LEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGIC 1131
+E K Y + + E G+E+++ E + K + K S +
Sbjct: 1289 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDS------- 1341
Query: 1132 LSISYYGSNGMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKE----KP 1187
S + +G++ E + + E SA + + Q K + +IK +E +
Sbjct: 1342 -EDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSEN 1400
Query: 1188 KESLKEEEHPKEEEKKEEEVEPEPVLQETLD 1218
K + +EEE KEEE++EEE E E E D
Sbjct: 1401 KSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1431
Score = 32.7 bits (73), Expect = 4.1
Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
Query: 878 IRTRAELELKSSANAKLTSASKIFSIKESKSNKG--ISKTEISDQEKEKEKEKIPFILEG 935
++T+A + K K +++ F K+ KS K ISK + ++ + E LE
Sbjct: 729 LKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKK---RQTQSESSNYDSELEK 785
Query: 936 SLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKE 995
+K+ + ++R+ K + E KKG DN ++ ++ ++ S + K+
Sbjct: 786 EIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQ 845
Query: 996 EQ 997
E+
Sbjct: 846 ER 847
Score = 32.3 bits (72), Expect = 5.3
Identities = 76/364 (20%), Positives = 136/364 (37%), Gaps = 43/364 (11%)
Query: 674 VDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLKLS--VPDNRQLLEQESIMK--A 729
V + +SV + ++ S S D N K + L K S V N E +I+K +
Sbjct: 647 VKEKQKLSVPVRKKDKRNSSDSAID--NPKPNKLPKSKQSETVDQNSDSDEMLAILKEVS 704
Query: 730 QPQHESLEQTTNNEIKD------DAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLMDWS 783
+ H S T NEI D T+A +K +K D + +S
Sbjct: 705 RMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSA---- 760
Query: 784 FTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRL----HCEYWNIA 839
K ++ + ++ + DS + S+ + ++R+ +
Sbjct: 761 -----KSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDE 815
Query: 840 LHSNVGFRNYLELVAKSIQDWITKEEAIYQESKM----------NEKIIRTRAELELKSS 889
HS G N K+ Q+ + + QE + + I+ R L K
Sbjct: 816 KHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQ 875
Query: 890 ANAKLTSASKIFSIKESKSNKGISKT-EISDQEKEKEKEKIPFILEGSLKAWKEEQHRLA 948
A+A K+ ++S ++ + K E ++ K + + + +G ++ +
Sbjct: 876 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQ 935
Query: 949 EEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESP 1008
+E ++KK KKG E KKK D +K +K + Y E S + K+ E EE
Sbjct: 936 SDETSEDDKKQSKKGTEE-KKKPSDFKKK----VIKMEQQY-ESSSDGTEKLPE-REEIC 988
Query: 1009 HQPE 1012
H P+
Sbjct: 989 HFPK 992
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 48.1 bits (113), Expect = 9e-05
Identities = 45/182 (24%), Positives = 85/182 (46%), Gaps = 30/182 (16%)
Query: 841 HSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTR------AELELKSSANAKL 894
H V RN ++ ++ +D +E + +E +E R R AELE ++ + K
Sbjct: 1363 HKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE-ENQRSYKQ 1421
Query: 895 TSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLR 954
+ ++E S++ S +E ++EKE+E+E EE+ EEE
Sbjct: 1422 KKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEE--------------EEEEEEEEEEDEN 1467
Query: 955 EEKKAEKKGKEAGKKKGKD--------NAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEE 1006
++ K+ KG++ +K KD NA KE+ +K+ +E+ +E+ ++ E+ +
Sbjct: 1468 DDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEER-RKRIAEREREREKLREVIEIEDA 1526
Query: 1007 SP 1008
SP
Sbjct: 1527 SP 1528
Score = 37.7 bits (86), Expect = 0.13
Identities = 23/105 (21%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 904 KESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRL--AEEERLREEKKAEK 961
KE K KG ++ ++S ++ E + + E ++ E++ R A++ L E +++ K
Sbjct: 1361 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1420
Query: 962 KGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEE 1006
+ K+ + K ++++ E+ + +++ KE+ +EE+ + +E E+
Sbjct: 1421 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1465
Score = 37.0 bits (84), Expect = 0.22
Identities = 31/143 (21%), Positives = 65/143 (45%), Gaps = 19/143 (13%)
Query: 875 EKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILE 934
EK + + E+K K++S E + ++ +S++ E E E+ P
Sbjct: 1355 EKKTKPKEHKEVKGRNRRKVSS--------EDSEDSDFQESGVSEEVSESEDEQRP---- 1402
Query: 935 GSLKAWKEEQHRLAEEERLREEKKAEK--KGKEAGKKKGKDNAEKEDSRSLKKKSPYKEK 992
+ ++ L E +R ++KK + K +E + K N+E+E+ K++ +E+
Sbjct: 1403 ---RTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEE--KEEEEEEEE 1457
Query: 993 SKEEQVKIQEVTEESPHQPEPKI 1015
+EE+ + + +SP + KI
Sbjct: 1458 EEEEEEEDENDDSKSPGKGRKKI 1480
Score = 35.8 bits (81), Expect = 0.48
Identities = 99/499 (19%), Positives = 182/499 (36%), Gaps = 81/499 (16%)
Query: 642 FAKQIRQQYVMKMNTQEAKQKADIKIKDRTLFVDQNLSMSVQDNESNREPSDPSQCDANN 701
F K I+Q +K T + ++K+ KI+D+T LS + + + CD++
Sbjct: 1028 FPKGIKQ---IKNGTTDGEKKSK-KIRDKTSKKKDELS-----DYAEKSTGKGDSCDSSE 1078
Query: 702 MKHSDLNNLKLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKAD-------- 753
K S N R L +S K Q S T +K+D +D
Sbjct: 1079 DKKS--KNGAYGREKKRCKLLGKSSRKRQDCSSS--DTEKYSMKEDGCNSSDKRLKRIEL 1134
Query: 754 ------SHEKKPKKMM-------VEADLEDIKKTQQR-SLMDWSFTEHFKPKVLLQVLQE 799
S ++ K++ E ED KK +QR S + K + L+ +
Sbjct: 1135 RERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTK 1194
Query: 800 AHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYL--ELVAKSI 857
+ S +D+ + + Q++ N+ L S+ GF E ++KS+
Sbjct: 1195 RKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSV 1254
Query: 858 QDWITKEEAIYQ-ESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTE 916
+ ++ E+++ +K++ + L S + + E K G E
Sbjct: 1255 PVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPE-----EGKKRTGKQNEE 1309
Query: 917 ISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAE 976
E+ K + + + EE + RL K G+ +KK K
Sbjct: 1310 NPGDEEAKNQ------VNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEH 1363
Query: 977 KEDSRSLKKK--SPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGS 1034
KE ++K S E S ++ + E ES + P+
Sbjct: 1364 KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR------------------ 1405
Query: 1035 NYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEE 1094
+ ++E + +++ +++V +D+ + N +E +KEE EE
Sbjct: 1406 -----SAKKAELEENQRSYKQKKKRRRIKVQEDSSSEN-KSNSEEEEEEKEE------EE 1453
Query: 1095 EEEGDEEQSLETEVSDAKN 1113
EEE +EE+ E E D+K+
Sbjct: 1454 EEEEEEEEEEEDENDDSKS 1472
Score = 33.9 bits (76), Expect = 1.8
Identities = 82/391 (20%), Positives = 143/391 (36%), Gaps = 63/391 (16%)
Query: 879 RTRAELELKSSANAKLTSASKI--FSIKE---SKSNKGISKTEISDQEKEKEKEKIPFIL 933
+ R +L KSS + S+S +S+KE + S+K + + E+ ++ K I
Sbjct: 1091 KKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQ 1150
Query: 934 EGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKK-------- 985
GS + EE +E+ + ++++ + KK K+K +++ R
Sbjct: 1151 SGSSSSDAEES---SEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSD 1207
Query: 986 -----KSPYKEKSKEEQVKIQEVTEE---SPHQP----------EPKITYPFHGYNMGNI 1027
++ E S +EQ KI+ VTE S H + + N
Sbjct: 1208 IEDDDQNSIGEGSSDEQ-KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDND 1266
Query: 1028 PTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHN------FMIHLNDPKEI 1081
P L E + P K R K N +N +
Sbjct: 1267 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS 1326
Query: 1082 VKKEEKGDYY----------LEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGIC 1131
+E K Y + + E G+E+++ E + K + K S +
Sbjct: 1327 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDS------- 1379
Query: 1132 LSISYYGSNGMAPEDKDPDLETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKE----KP 1187
S + +G++ E + + E SA + + Q K + +IK +E +
Sbjct: 1380 -EDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSEN 1438
Query: 1188 KESLKEEEHPKEEEKKEEEVEPEPVLQETLD 1218
K + +EEE KEEE++EEE E E E D
Sbjct: 1439 KSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1469
Score = 32.7 bits (73), Expect = 4.1
Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
Query: 878 IRTRAELELKSSANAKLTSASKIFSIKESKSNKG--ISKTEISDQEKEKEKEKIPFILEG 935
++T+A + K K +++ F K+ KS K ISK + ++ + E LE
Sbjct: 767 LKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKK---RQTQSESSNYDSELEK 823
Query: 936 SLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKE 995
+K+ + ++R+ K + E KKG DN ++ ++ ++ S + K+
Sbjct: 824 EIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQ 883
Query: 996 EQ 997
E+
Sbjct: 884 ER 885
Score = 32.3 bits (72), Expect = 5.3
Identities = 76/364 (20%), Positives = 136/364 (37%), Gaps = 43/364 (11%)
Query: 674 VDQNLSMSVQDNESNREPSDPSQCDANNMKHSDLNNLKLS--VPDNRQLLEQESIMK--A 729
V + +SV + ++ S S D N K + L K S V N E +I+K +
Sbjct: 685 VKEKQKLSVPVRKKDKRNSSDSAID--NPKPNKLPKSKQSETVDQNSDSDEMLAILKEVS 742
Query: 730 QPQHESLEQTTNNEIKD------DAVTKADSHEKKPKKMMVEADLEDIKKTQQRSLMDWS 783
+ H S T NEI D T+A +K +K D + +S
Sbjct: 743 RMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSA---- 798
Query: 784 FTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNRQRL----HCEYWNIA 839
K ++ + ++ + DS + S+ + ++R+ +
Sbjct: 799 -----KSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDE 853
Query: 840 LHSNVGFRNYLELVAKSIQDWITKEEAIYQESKM----------NEKIIRTRAELELKSS 889
HS G N K+ Q+ + + QE + + I+ R L K
Sbjct: 854 KHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQ 913
Query: 890 ANAKLTSASKIFSIKESKSNKGISKT-EISDQEKEKEKEKIPFILEGSLKAWKEEQHRLA 948
A+A K+ ++S ++ + K E ++ K + + + +G ++ +
Sbjct: 914 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQ 973
Query: 949 EEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESP 1008
+E ++KK KKG E KKK D +K +K + Y E S + K+ E EE
Sbjct: 974 SDETSEDDKKQSKKGTEE-KKKPSDFKKK----VIKMEQQY-ESSSDGTEKLPE-REEIC 1026
Query: 1009 HQPE 1012
H P+
Sbjct: 1027 HFPK 1030
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 47.8 bits (112), Expect = 1e-04
Identities = 66/291 (22%), Positives = 118/291 (40%), Gaps = 48/291 (16%)
Query: 935 GSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKK-KSPYKEKS 993
G K E + RL E+ G+ G+ + + E+E+ + +KK K +E S
Sbjct: 1464 GDSSMHKYEMPQYGSRRRLLPPAGQEEYGEVVGEAEEEYEEEEEEPKKIKKPKVEIREPS 1523
Query: 994 KEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMF 1053
+EE+V VT E P EP T I ++ G G +++E +
Sbjct: 1524 EEEEVV---VTIEKPPAAEPTYTTWKRARIFPMIFKKVRG-----LADKRGIVDLEGEEW 1575
Query: 1054 EKGPTFIKVRVVKDNHNFMIHLNDPKEIVK------KEEKGDY--YLEEEEEGDEEQSLE 1105
++ R+ +++ +++ D +E + +E DY Y EEE E E ++ E
Sbjct: 1576 QR-------RLEEEDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTE 1628
Query: 1106 TEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAPEDKDPDLETILNIPSALTPTV 1165
E S+++ + + S + E+ S + + P +E + +
Sbjct: 1629 EE-SESETPSEEEESSTPESEESESTESEGEKARKNIVLARRRPMVEEVKEV-------- 1679
Query: 1166 VPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPEPVLQET 1216
KG+ KE+P+E KE + +EE +EEE P PV + T
Sbjct: 1680 ------------KGR---KEEPQEEQKEPKMEEEEHSEEEESGPAPVEEST 1715
Score = 33.5 bits (75), Expect = 2.4
Identities = 37/178 (20%), Positives = 72/178 (40%), Gaps = 15/178 (8%)
Query: 847 RNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKES 906
++YL+L Q+ T+ +E ++ + E E S + S S+ S +E
Sbjct: 1584 KDYLKLTLD--QEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESESETPSEEEE 1641
Query: 907 KSNKGISKTEISDQEKEKEKEKI------PFILE-GSLKAWKEE------QHRLAEEERL 953
S ++E ++ E EK ++ I P + E +K KEE + ++ EEE
Sbjct: 1642 SSTPESEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQEEQKEPKMEEEEHS 1701
Query: 954 REEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQP 1011
EE+ +E+ + +D E+ + S + + + + E +E P
Sbjct: 1702 EEEESGPAPVEESTDPEAQDIPEEGSAESASVEGGVESEEESESGSSSSSSESQSGGP 1759
Score = 32.7 bits (73), Expect = 4.1
Identities = 37/154 (24%), Positives = 56/154 (36%), Gaps = 17/154 (11%)
Query: 881 RAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAW 940
R E E K L S ES+ TE S++E E E
Sbjct: 1578 RLEEEDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESE--------FSESETTEE 1629
Query: 941 KEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKI 1000
+ E +EEE + E + E+ +K + N L ++ P E+ KE + +
Sbjct: 1630 ESESETPSEEEESSTPESEESESTESEGEKARKNIV------LARRRPMVEEVKEVKGRK 1683
Query: 1001 QEVTEESPHQPEPKITYPFHGYNMGNIPTQISGS 1034
+E EE Q EPK+ H + P + S
Sbjct: 1684 EEPQEE---QKEPKMEEEEHSEEEESGPAPVEES 1714
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 47.8 bits (112), Expect = 1e-04
Identities = 71/355 (20%), Positives = 132/355 (37%), Gaps = 51/355 (14%)
Query: 859 DWITKEEAIYQESKMNEKIIRTRAELE----LKSSANAKLTSASKIFSIKESKSNKGISK 914
D I+ E + +E K + R R E E +K+ + K+ +E + + +
Sbjct: 249 DEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERER 308
Query: 915 TEISDQEKEKEKEKIPFILEGSLKAWK----EEQHRLAEEERLREEKKAEKKGKEAGKKK 970
E ++E+ +E+EK +K + EE+ R+ EEE+ E++ K +E +
Sbjct: 309 REAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 368
Query: 971 GKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQ 1030
+ A E+ K + + K EE+ + T+ + E KI +
Sbjct: 369 ERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKI--------------E 414
Query: 1031 ISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDY 1090
N D Q V K E+ T ++ + K L + K KKEE D
Sbjct: 415 GKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK--------LQEDKPTFKKEEIKDE 466
Query: 1091 YLEEEEEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAPEDKDPD 1150
+++++E EE + + K F++ S NG K
Sbjct: 467 KIKKDKEPKEEVKSFMD----RKKGFTEVKS-----------------QNGEFMTHKLKH 505
Query: 1151 LETILNIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKKEE 1205
E + P PQ +A +++ + + + EE K ++K++E
Sbjct: 506 TENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQE 560
Score = 42.4 bits (98), Expect = 0.005
Identities = 32/121 (26%), Positives = 65/121 (53%), Gaps = 6/121 (4%)
Query: 881 RAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAW 940
RA ++ K + A A K ++E + +G +TE + EK K+K++ + LK
Sbjct: 516 RASVDTKEAEGAPQVEAGK--RLEELRRRRG--ETESEEFEKLKQKQQEAALELEELKKK 571
Query: 941 KEEQHR-LAEEERLREEKKAEKK-GKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQV 998
+EE+ + L EEE+ R++++A++K +E K++ K+ E+ + + +K+ E +
Sbjct: 572 REERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDK 631
Query: 999 K 999
K
Sbjct: 632 K 632
Score = 40.4 bits (93), Expect = 0.020
Identities = 98/507 (19%), Positives = 197/507 (38%), Gaps = 78/507 (15%)
Query: 656 TQEAKQKADIKIKDRTLFVDQNLSMSVQDN------ESNREPSDPSQCDANNMKHSDL-- 707
T E ++K++ + + + + ++ S Q N E+ +E + + + K +
Sbjct: 146 TTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGE 205
Query: 708 NNLKLSVPDNRQLLEQESIMKA---------QPQHESLEQTTNNEIKD-DAVTKADSHEK 757
N +++ V + ++E+++ + +P+ E + ++EI + + + D
Sbjct: 206 NQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERA 265
Query: 758 KPKKMMVEAD-LEDIKKTQQRSLMDWSFTEHFKPKVLLQVLQ--EAHKQYRCVDSYYHTQ 814
+ ++ +EA+ E IK Q + + D + K Q + EA ++ R +
Sbjct: 266 EAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAA 325
Query: 815 DNSLLLVFHNPMNRQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMN 874
+ RQR+ E E A + I +EE E +
Sbjct: 326 EE-----------RQRIKEE----------------EKRAAEERQRIKEEEKRAAEERQR 358
Query: 875 EKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILE 934
K RA E + A A+ +K+ +E K NK + + + + QE + + EK+ +E
Sbjct: 359 IKEEEKRAAEE-RQRARAEEEEKAKV---EEQKRNKQLEEKKHAMQETKIKGEKVEQKIE 414
Query: 935 GS----------------LKAWKEEQHRL--AEEERLREEKKAEKKGKEAGKKKGKDNAE 976
G LK EE+ A+ E+L+E+K KK + +K KD
Sbjct: 415 GKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEP 474
Query: 977 KEDSRSL--KKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGS 1034
KE+ +S +KK + KS+ + ++ P P +G
Sbjct: 475 KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGK 534
Query: 1035 NYYLYPSDGGQIE---VEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYY 1091
G+ E EK ++ +++ +K + + +E +K+E+ D
Sbjct: 535 RLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRK 594
Query: 1092 LEEEEEGDEEQSLETEVSDAKNKAFSK 1118
L EEE E++ L+ E+ + +A K
Sbjct: 595 LREEE---EKRRLKEEIERRRAEAAEK 618
Score = 36.6 bits (83), Expect = 0.28
Identities = 28/139 (20%), Positives = 68/139 (48%), Gaps = 7/139 (5%)
Query: 879 RTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGS-- 936
R + LE + + +T AS S+ + ++ E +++E++ E + + +E +
Sbjct: 110 RLQEALERQKEFDPTITDAS--LSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETET 167
Query: 937 -LKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKE 995
K++++ R AEE + +++K E++ E K+G + + +K + +E++
Sbjct: 168 VTKSYQKNDWRDAEENKKEDKEKEEEE--EEKPKRGSIGENQVEVMVEEKTTESQEETVV 225
Query: 996 EQVKIQEVTEESPHQPEPK 1014
+K +++ E P Q E +
Sbjct: 226 MSLKNGQISSEEPKQEEER 244
Score = 35.4 bits (80), Expect = 0.63
Identities = 43/194 (22%), Positives = 80/194 (41%), Gaps = 36/194 (18%)
Query: 923 EKEKEKIPFILEGSLKA-WKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSR 981
E++KE P I + SL + Q+ AE E +E+K+E + ++ E E++
Sbjct: 116 ERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESR---------QERYEIEETE 166
Query: 982 SLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYYLYPS 1041
++ K + E+ K ++ +E + +PK G+I
Sbjct: 167 TVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPK---------RGSI-------------- 203
Query: 1042 DGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEEEEGDEE 1101
G+ +VE + EK + VV N I +PK+ ++E+ D + E+ +EE
Sbjct: 204 --GENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSD-EISHHEKMEEE 260
Query: 1102 QSLETEVSDAKNKA 1115
E A+ +A
Sbjct: 261 DKERAEAERARLEA 274
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 47.4 bits (111), Expect = 2e-04
Identities = 140/709 (19%), Positives = 259/709 (36%), Gaps = 101/709 (14%)
Query: 838 IALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAE--LELKSSANAKLT 895
I L+S + + E K + +E + ES + R+R E L +S+ T
Sbjct: 1670 IELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGT 1729
Query: 896 SASKIFSIKE-SKSNKGISKTEISDQEKEKEKEKIPFI--LEGSLKA--WKEEQHRLAEE 950
S + + S+ E S S+ K E Q K + + P + +E S + +EE+ L E+
Sbjct: 1730 SPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQ 1789
Query: 951 ERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKK-----SPYKEKSKEEQVK----IQ 1001
E+ RE ++ ++K KK KD + R K SP ++ S E+++ ++
Sbjct: 1790 EKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEME 1849
Query: 1002 EVTEESPHQPEPKITYPFHGYNMG-----------NIPTQISGSNYYLY-PSDGGQIEVE 1049
E+ S + P I G+ + +PT +S LY P+D E
Sbjct: 1850 ELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVS-----LYSPTD------E 1898
Query: 1050 KTMFEKGPTFIKVRVVKDNHNFMIH-LNDPKEIVKKEEKGDYYLEEEEEGD---EEQSLE 1105
+++ +K + ++ ++ + M+H + K E+ + + +E G E+ E
Sbjct: 1899 QSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYE 1958
Query: 1106 TEVSDAKNKAFSKFGSFSATLENG----------ICLSISYYGSNGMAPEDKDPDLETIL 1155
+ V D N + ENG I LS Y D + +
Sbjct: 1959 SLVEDTYNGSVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELE 2018
Query: 1156 NIPSAL-TPTVVPVIVTVPQSKA---KGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPEP 1211
++ S + +V +P+S G + + + L + + EE K ++++ P
Sbjct: 2019 SLHSVVPQEDIVSSSFIIPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTP 2078
Query: 1212 ------------VLQETLDVPTF--QSLNVSCPSGLLLTFIGQESTGQYVIDEEPTWDIM 1257
+ + T+D SL S SG LT +ST + D+
Sbjct: 2079 GSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLT----DSTSSATLSIP---DVK 2131
Query: 1258 VRQSYPQRVKHYEFYKTVMPPAEQEASRVITSQGTVVKYM--LDGSTQILFADGAVSRSP 1315
+ Q + E + +E +I + ++ Y + +T + +D S
Sbjct: 2132 ITQHFSTE----EIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSS 2187
Query: 1316 NSGLICPPSEMPATPHSGDLMDSISQQKSETIPSEITNTKKGKSHKSQSSMAHKGEIHDP 1375
S + S P T +DSI+ +E + TK S + SS G I D
Sbjct: 2188 VSSVCTTDSSSPIT-----TLDSITTVYTEPVD---MITKFEDSEEISSSTYFPGSIID- 2238
Query: 1376 PPEAVQTVTPVEVHIGTWFTTTPEGNRIGTKGLERIADLTPLLSFQATDPVNGTVMTTRE 1435
P E+ + T P+G + ++D+ + G V T
Sbjct: 2239 --------YPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVS 2290
Query: 1436 DKVVIVERKDGTRIVDHADGTRITTFYQVYEDQIILPDDQETTEGPRTV 1484
++I E+ + I + Y D+ L ++ + TV
Sbjct: 2291 TDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETV 2339
Score = 40.0 bits (92), Expect = 0.026
Identities = 83/364 (22%), Positives = 142/364 (39%), Gaps = 58/364 (15%)
Query: 870 ESKMNEKIIRTRAELELKSSANAKLTSASKIF--SIKESKSNKGISKTEISDQEKEKEK- 926
ES + + + +L K K T A K+ +KE+ S + I +DQ++E+ K
Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVK-TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL 1200
Query: 927 ---------EKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEK 977
EK P E L +EE+ R E++ L EEKK + K+ + K +A +
Sbjct: 1201 EKDKASALQEKKPLPEEKKLIP-EEEKIRSEEKKPLLEEKKPTPEDKKL-LPEAKTSAPE 1258
Query: 978 EDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYY 1037
E L K + K E ++ T + QP+ K M +P SG+
Sbjct: 1259 EQKHDLLKSQVQIAEEKLEG-RVAPKTVQEGKQPQTK---------MEGLP---SGTPQS 1305
Query: 1038 LYPSDGGQIEVEKTMFE--KGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEE 1095
L D + KT+ E + P K V+ ++ K+++K D ++
Sbjct: 1306 LPKEDD---KTTKTIKEQPQPPCTAKPDQVEPG---------KEKTEKEDDKSDTSSSQQ 1353
Query: 1096 EEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAPEDKDPDLETIL 1155
+ + S SD + + + S T E I + + + DL
Sbjct: 1354 PKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDL---- 1409
Query: 1156 NIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPEPVLQE 1215
+ L TV+ ++ + A K + K +P E E PK++EK + L E
Sbjct: 1410 ---AKLESTVLSILEAQASTLADEKSEKKTQPHE--VSPEQPKDQEKTQS-------LSE 1457
Query: 1216 TLDV 1219
TL++
Sbjct: 1458 TLEI 1461
Score = 33.9 bits (76), Expect = 1.8
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 10/76 (13%)
Query: 1157 IPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKK----EEEV---EP 1209
+ L+ +P +VT Q + + K+ EK K S +E+ P EEKK EE++ E
Sbjct: 1176 VKETLSMEKIPPMVTTDQKQEESKL---EKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
Query: 1210 EPVLQETLDVPTFQSL 1225
+P+L+E P + L
Sbjct: 1233 KPLLEEKKPTPEDKKL 1248
Score = 33.5 bits (75), Expect = 2.4
Identities = 65/353 (18%), Positives = 136/353 (38%), Gaps = 40/353 (11%)
Query: 679 SMSVQDNESNREPS-----DPSQCDANNMKHSDLNNLKLSVPDNRQLLEQESIMKAQPQH 733
S+S D +S+ PS Q A + H L + +L E+E ++K Q +
Sbjct: 1733 SVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQ 1792
Query: 734 ESLEQ-----TTNNEIKDDAVTKADSHEKKPK----------------KMMVEADLEDIK 772
+EQ ++ KD +A ++PK ++ A++E++
Sbjct: 1793 REIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELH 1852
Query: 773 KT--QQRSLMDWSFTEHFK--PKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNR 828
++ + S S E F+ P+ +++V Q+ +K V Y T + S++
Sbjct: 1853 RSSCSEYSPSIESDPEGFEISPEKIIEV-QKVYKLPTAVSLYSPTDEQSIMQK-EGSQKA 1910
Query: 829 QRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKS 888
+ E + +H Y A + +D + ++E +Y + + I + E
Sbjct: 1911 LKSAEEMYEEMMHKT---HKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNG 1967
Query: 889 SANAK-LTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRL 947
S + LT + + K + K +S+Q E +KI + + + E H +
Sbjct: 1968 SVDGSLLTRQEEENGFMQQKGRE--QKIRLSEQIYEDPMQKITDLQKEFYEL--ESLHSV 2023
Query: 948 AEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKI 1000
+E + + E + +E+ + L + Y+E K +Q+++
Sbjct: 2024 VPQEDIVSSSFIIPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQL 2076
Score = 32.0 bits (71), Expect = 7.0
Identities = 42/197 (21%), Positives = 78/197 (39%), Gaps = 27/197 (13%)
Query: 113 IMDSGEKLTLPLIGKLLKFQLLQIKFKDQQRRENEKKVIEDKPKLEKDKGKAKSPKEKKA 172
I DS E+ L +LLK Q Q + + QQR+ + K K +KDK + ++ + ++
Sbjct: 1770 IEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSK-------KSKKDKDELRAQRRRER 1822
Query: 173 PSAKPAKGKGKDQPEANAPVKKTTQLKRRGEDDHTNRYIDDEPDDGAQHYIIVVGFNNPQ 232
P P+ + T +L++ E + +R E + ++P+
Sbjct: 1823 PKTPPSNLSPIED------ASPTEELRQAAEMEELHRSSCSEYSPSIE--------SDPE 1868
Query: 233 LLAIMAELGIPITSVIKISSENYEPLQTHLAAVNQQQEVLLQSEDLEAEKLKKENAIKEL 292
I E I + V K+ P L + +Q ++ + +A K +E + +
Sbjct: 1869 GFEISPEKIIEVQKVYKL------PTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEMM 1922
Query: 293 KTFWKYLEPVLNNEKPE 309
KY NE+ E
Sbjct: 1923 HKTHKYKAFPAANERDE 1939
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 47.4 bits (111), Expect = 2e-04
Identities = 140/709 (19%), Positives = 259/709 (36%), Gaps = 101/709 (14%)
Query: 838 IALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAE--LELKSSANAKLT 895
I L+S + + E K + +E + ES + R+R E L +S+ T
Sbjct: 1670 IELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGT 1729
Query: 896 SASKIFSIKE-SKSNKGISKTEISDQEKEKEKEKIPFI--LEGSLKA--WKEEQHRLAEE 950
S + + S+ E S S+ K E Q K + + P + +E S + +EE+ L E+
Sbjct: 1730 SPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQ 1789
Query: 951 ERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKK-----SPYKEKSKEEQVK----IQ 1001
E+ RE ++ ++K KK KD + R K SP ++ S E+++ ++
Sbjct: 1790 EKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEME 1849
Query: 1002 EVTEESPHQPEPKITYPFHGYNMG-----------NIPTQISGSNYYLY-PSDGGQIEVE 1049
E+ S + P I G+ + +PT +S LY P+D E
Sbjct: 1850 ELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVS-----LYSPTD------E 1898
Query: 1050 KTMFEKGPTFIKVRVVKDNHNFMIH-LNDPKEIVKKEEKGDYYLEEEEEGD---EEQSLE 1105
+++ +K + ++ ++ + M+H + K E+ + + +E G E+ E
Sbjct: 1899 QSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYE 1958
Query: 1106 TEVSDAKNKAFSKFGSFSATLENG----------ICLSISYYGSNGMAPEDKDPDLETIL 1155
+ V D N + ENG I LS Y D + +
Sbjct: 1959 SLVEDTYNGSVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELE 2018
Query: 1156 NIPSAL-TPTVVPVIVTVPQSKA---KGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPEP 1211
++ S + +V +P+S G + + + L + + EE K ++++ P
Sbjct: 2019 SLHSVVPQEDIVSSSFIIPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTP 2078
Query: 1212 ------------VLQETLDVPTF--QSLNVSCPSGLLLTFIGQESTGQYVIDEEPTWDIM 1257
+ + T+D SL S SG LT +ST + D+
Sbjct: 2079 GSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLT----DSTSSATLSIP---DVK 2131
Query: 1258 VRQSYPQRVKHYEFYKTVMPPAEQEASRVITSQGTVVKYM--LDGSTQILFADGAVSRSP 1315
+ Q + E + +E +I + ++ Y + +T + +D S
Sbjct: 2132 ITQHFSTE----EIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSS 2187
Query: 1316 NSGLICPPSEMPATPHSGDLMDSISQQKSETIPSEITNTKKGKSHKSQSSMAHKGEIHDP 1375
S + S P T +DSI+ +E + TK S + SS G I D
Sbjct: 2188 VSSVCTTDSSSPIT-----TLDSITTVYTEPVD---MITKFEDSEEISSSTYFPGSIID- 2238
Query: 1376 PPEAVQTVTPVEVHIGTWFTTTPEGNRIGTKGLERIADLTPLLSFQATDPVNGTVMTTRE 1435
P E+ + T P+G + ++D+ + G V T
Sbjct: 2239 --------YPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVS 2290
Query: 1436 DKVVIVERKDGTRIVDHADGTRITTFYQVYEDQIILPDDQETTEGPRTV 1484
++I E+ + I + Y D+ L ++ + TV
Sbjct: 2291 TDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETV 2339
Score = 40.0 bits (92), Expect = 0.026
Identities = 83/364 (22%), Positives = 142/364 (39%), Gaps = 58/364 (15%)
Query: 870 ESKMNEKIIRTRAELELKSSANAKLTSASKIF--SIKESKSNKGISKTEISDQEKEKEK- 926
ES + + + +L K K T A K+ +KE+ S + I +DQ++E+ K
Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVK-TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL 1200
Query: 927 ---------EKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEK 977
EK P E L +EE+ R E++ L EEKK + K+ + K +A +
Sbjct: 1201 EKDKASALQEKKPLPEEKKLIP-EEEKIRSEEKKPLLEEKKPTPEDKKL-LPEAKTSAPE 1258
Query: 978 EDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYNMGNIPTQISGSNYY 1037
E L K + K E ++ T + QP+ K M +P SG+
Sbjct: 1259 EQKHDLLKSQVQIAEEKLEG-RVAPKTVQEGKQPQTK---------MEGLP---SGTPQS 1305
Query: 1038 LYPSDGGQIEVEKTMFE--KGPTFIKVRVVKDNHNFMIHLNDPKEIVKKEEKGDYYLEEE 1095
L D + KT+ E + P K V+ ++ K+++K D ++
Sbjct: 1306 LPKEDD---KTTKTIKEQPQPPCTAKPDQVEPG---------KEKTEKEDDKSDTSSSQQ 1353
Query: 1096 EEGDEEQSLETEVSDAKNKAFSKFGSFSATLENGICLSISYYGSNGMAPEDKDPDLETIL 1155
+ + S SD + + + S T E I + + + DL
Sbjct: 1354 PKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDL---- 1409
Query: 1156 NIPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKKEEEVEPEPVLQE 1215
+ L TV+ ++ + A K + K +P E E PK++EK + L E
Sbjct: 1410 ---AKLESTVLSILEAQASTLADEKSEKKTQPHE--VSPEQPKDQEKTQS-------LSE 1457
Query: 1216 TLDV 1219
TL++
Sbjct: 1458 TLEI 1461
Score = 33.9 bits (76), Expect = 1.8
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 10/76 (13%)
Query: 1157 IPSALTPTVVPVIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKK----EEEV---EP 1209
+ L+ +P +VT Q + + K+ EK K S +E+ P EEKK EE++ E
Sbjct: 1176 VKETLSMEKIPPMVTTDQKQEESKL---EKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
Query: 1210 EPVLQETLDVPTFQSL 1225
+P+L+E P + L
Sbjct: 1233 KPLLEEKKPTPEDKKL 1248
Score = 33.5 bits (75), Expect = 2.4
Identities = 65/353 (18%), Positives = 136/353 (38%), Gaps = 40/353 (11%)
Query: 679 SMSVQDNESNREPS-----DPSQCDANNMKHSDLNNLKLSVPDNRQLLEQESIMKAQPQH 733
S+S D +S+ PS Q A + H L + +L E+E ++K Q +
Sbjct: 1733 SVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQ 1792
Query: 734 ESLEQ-----TTNNEIKDDAVTKADSHEKKPK----------------KMMVEADLEDIK 772
+EQ ++ KD +A ++PK ++ A++E++
Sbjct: 1793 REIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELH 1852
Query: 773 KT--QQRSLMDWSFTEHFK--PKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMNR 828
++ + S S E F+ P+ +++V Q+ +K V Y T + S++
Sbjct: 1853 RSSCSEYSPSIESDPEGFEISPEKIIEV-QKVYKLPTAVSLYSPTDEQSIMQK-EGSQKA 1910
Query: 829 QRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKS 888
+ E + +H Y A + +D + ++E +Y + + I + E
Sbjct: 1911 LKSAEEMYEEMMHKT---HKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNG 1967
Query: 889 SANAK-LTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRL 947
S + LT + + K + K +S+Q E +KI + + + E H +
Sbjct: 1968 SVDGSLLTRQEEENGFMQQKGRE--QKIRLSEQIYEDPMQKITDLQKEFYEL--ESLHSV 2023
Query: 948 AEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKI 1000
+E + + E + +E+ + L + Y+E K +Q+++
Sbjct: 2024 VPQEDIVSSSFIIPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQL 2076
Score = 32.0 bits (71), Expect = 7.0
Identities = 42/197 (21%), Positives = 78/197 (39%), Gaps = 27/197 (13%)
Query: 113 IMDSGEKLTLPLIGKLLKFQLLQIKFKDQQRRENEKKVIEDKPKLEKDKGKAKSPKEKKA 172
I DS E+ L +LLK Q Q + + QQR+ + K K +KDK + ++ + ++
Sbjct: 1770 IEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSK-------KSKKDKDELRAQRRRER 1822
Query: 173 PSAKPAKGKGKDQPEANAPVKKTTQLKRRGEDDHTNRYIDDEPDDGAQHYIIVVGFNNPQ 232
P P+ + T +L++ E + +R E + ++P+
Sbjct: 1823 PKTPPSNLSPIED------ASPTEELRQAAEMEELHRSSCSEYSPSIE--------SDPE 1868
Query: 233 LLAIMAELGIPITSVIKISSENYEPLQTHLAAVNQQQEVLLQSEDLEAEKLKKENAIKEL 292
I E I + V K+ P L + +Q ++ + +A K +E + +
Sbjct: 1869 GFEISPEKIIEVQKVYKL------PTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEMM 1922
Query: 293 KTFWKYLEPVLNNEKPE 309
KY NE+ E
Sbjct: 1923 HKTHKYKAFPAANERDE 1939
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 47.0 bits (110), Expect = 2e-04
Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 4/140 (2%)
Query: 862 TKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQE 921
T E + ES EK I+ + + K S + S K +SK K + S
Sbjct: 273 TSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEK----DKSKKRKLHEELSSSHHN 328
Query: 922 KEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSR 981
+EK KEK F+ S + + H ++++ + EK+G E + + + +E SR
Sbjct: 329 REKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSR 388
Query: 982 SLKKKSPYKEKSKEEQVKIQ 1001
+ +SP K +E + + Q
Sbjct: 389 RSRSRSPGSYKQRETRKRAQ 408
Score = 38.5 bits (88), Expect = 0.074
Identities = 35/171 (20%), Positives = 71/171 (41%), Gaps = 5/171 (2%)
Query: 838 IALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSA 897
IA N GF ++ +++ +E + E + + ++ ++ L + KL
Sbjct: 171 IAEMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKS---LTTKQKQKLLRK 227
Query: 898 SKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEK 957
K+ K ++ K + S + +K K S + E +E E +EK
Sbjct: 228 LDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEK 287
Query: 958 KAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESP 1008
K ++K ++ K G +N++ E+ KK+ ++E S + E +E P
Sbjct: 288 KIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNR--EKAKEKP 336
>gi|6005757 chromatin-specific transcription elongation factor large
subunit [Homo sapiens]
Length = 1047
Score = 47.0 bits (110), Expect = 2e-04
Identities = 41/154 (26%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 897 ASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFIL-EGSLKAWKEEQHR---LAEEER 952
A+ + S+K+ N GI ++E+E+EK++ +L GS A E+ R AEE+R
Sbjct: 415 ATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKR 474
Query: 953 LREEKK-AEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKS---KEEQVKIQEVTEESP 1008
+K+ A + +EA ++ + E++ ++ K YK S KE ++ ++ +
Sbjct: 475 RAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKK 534
Query: 1009 HQ----PEPKITYPFHGYNMGNIPTQISGSNYYL 1038
++ P I PFH + NI + G YL
Sbjct: 535 YETVIMPVFGIATPFHIATIKNISMSVEGDYTYL 568
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 46.6 bits (109), Expect = 3e-04
Identities = 41/169 (24%), Positives = 75/169 (44%), Gaps = 21/169 (12%)
Query: 853 VAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIK-------- 904
+A ++ I KEE + +E K+ R +E+ L + I +K
Sbjct: 2146 LANKMRRMINKEEKMTEEES---KLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKE 2202
Query: 905 -------ESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEK 957
+ K + + + E + E+ + + + + + +EE+ R EEER EE
Sbjct: 2203 AKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEV 2262
Query: 958 KAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEE 1006
+ E++ ++ ++ + EKE+ KKK KEK KEE + +EV EE
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKK---KEKKKEEVQEKEEVFEE 2308
Score = 44.7 bits (104), Expect = 0.001
Identities = 67/319 (21%), Positives = 140/319 (43%), Gaps = 32/319 (10%)
Query: 711 KLSVPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADLED 770
KL+ + + ++ES+ K + + + +D+ K E K KM +++
Sbjct: 2051 KLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDER--KLTQEEIKMTKMKRALFVKE 2108
Query: 771 IKKTQQRSLMD---WSFTEHFKPKVLLQVLQEAHKQYRCVDSYYHTQDNSLLLVFHNPMN 827
+ + ++S +D W F+E K L + ++ ++ R + + N +
Sbjct: 2109 RRLSIEQSKLDIKEWDFSE--KRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESK 2166
Query: 828 RQRLHCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKIIRTRAELELK 887
R H E I G E++ + W ++EA + K EK E+E +
Sbjct: 2167 LARKHSEV--ILDDEEEGGIEEEEVIPFLKRRWRKRKEA-KRGDKPKEKFSSQVDEVESE 2223
Query: 888 SSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRL 947
+ ++ S +ES S++ + E ++E+E+E+E++ E + + E+ ++
Sbjct: 2224 EHFSEEMESLLDELEKQESLSSE---EEEEREEEEEREEEEVREEEEERKEEEEGEEKQV 2280
Query: 948 AEEERLREEKKAEKKGKEAGKKKG-----------------KDNAEKEDSRSLKKKSPYK 990
+EE +++KK EKK +E +K+ D E+E+S SL+++ +
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340
Query: 991 EK--SKEEQVKIQEVTEES 1007
++ KE+Q K+QE +S
Sbjct: 2341 KEILKKEKQFKLQEQRRKS 2359
Score = 40.8 bits (94), Expect = 0.015
Identities = 59/269 (21%), Positives = 114/269 (42%), Gaps = 60/269 (22%)
Query: 857 IQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTE 916
I++W E+ + +K +K+ R + +L K ++ + + + +ESK + S+
Sbjct: 2120 IKEWDFSEKRS-ELTKDEKKLARKQRKLANKMR---RMINKEEKMTEEESKLARKHSEVI 2175
Query: 917 ISDQEKE--KEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGK-- 972
+ D+E+ +E+E IPF+ + W++ + E R +K EK + + + +
Sbjct: 2176 LDDEEEGGIEEEEVIPFLK----RRWRKRK------EAKRGDKPKEKFSSQVDEVESEEH 2225
Query: 973 ---------DNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPEPKITYPFHGYN 1023
D EK++S S +++ +E+ + E+ +++E EE + E
Sbjct: 2226 FSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEE----------- 2274
Query: 1024 MGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIVK 1083
G + +VEK EK K K+ + + KE +
Sbjct: 2275 -------------------GEEKQVEKEEEEKKKK--KKEKKKEEVQEKEEVFEEKEEIM 2313
Query: 1084 KEEKGDYYLEEEEEGDEEQSLETEVSDAK 1112
EE+ + +EEEE +E SLE EV K
Sbjct: 2314 SEEETESLSDEEEE-EESCSLEEEVDREK 2341
Score = 37.4 bits (85), Expect = 0.17
Identities = 62/305 (20%), Positives = 126/305 (41%), Gaps = 43/305 (14%)
Query: 714 VPDNRQLLEQESIMKAQPQHESLEQTTNNEIKDDAVTKADSHEKKPKKMMVEADL----- 768
V + ++L E+E + Q + S E+T + ++ + + + + +KM E +
Sbjct: 1743 VEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKR 1802
Query: 769 -----EDIKKTQQRSLMDWSFTEHFKPKVLL----QVLQEAHKQYRCVDSYYHTQDNSLL 819
+ +K Q+R S E K K++L + QE + + ++N L
Sbjct: 1803 EQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLY 1862
Query: 820 LVFHNPMNRQRL-HCEYWNIALHSNVGFRNYLELVAKSIQDWITKEEAIYQESKMNEKII 878
N++RL H + + + + +G N + +++ +T+E+ + K EK+
Sbjct: 1863 -------NKERLTHSKKQLVQVKNKLGMFNK---ILAQVEEKLTQEKETVIKKK--EKLA 1910
Query: 879 RTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKEKEKEKIPFILEGSLK 938
T +L + AK K + + K + K + +++ L G L
Sbjct: 1911 ETEKKLVQVEDSLAK-----KQEKLAQEKMKLALEKAMVQGKKR----------LRGELD 1955
Query: 939 AWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSLKKKSPYKEK-SKEEQ 997
KEE+ E +RL EEK +GKE K ++ + ++ ++ K S EE+
Sbjct: 1956 IAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEK 2015
Query: 998 VKIQE 1002
+ + E
Sbjct: 2016 ILLHE 2020
Score = 37.0 bits (84), Expect = 0.22
Identities = 35/143 (24%), Positives = 67/143 (46%), Gaps = 3/143 (2%)
Query: 864 EEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKE 923
E+ + K+ +K + E E + KL I + K + + + ++E
Sbjct: 1656 EKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELA 1715
Query: 924 KEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKGKEAGKKKGKDNAEKEDSRSL 983
+E E++ + +E +WKEE+ EE +L EEKK + +EA + + +E+E +
Sbjct: 1716 QELEELEWDMEEL--SWKEEELN-QEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQ 1772
Query: 984 KKKSPYKEKSKEEQVKIQEVTEE 1006
+++ +EK K Q K + EE
Sbjct: 1773 EEELLIQEKEKLAQHKEKMPEEE 1795
Score = 35.8 bits (81), Expect = 0.48
Identities = 41/168 (24%), Positives = 77/168 (45%), Gaps = 22/168 (13%)
Query: 865 EAIYQESKMNE-KIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGISKTEISDQEKE 923
+A+ +E K+ + K T+ E ++ T K+ +K+ I +T K+
Sbjct: 1405 KAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKV--VKQEGKLVMIERTPSWQDWKK 1462
Query: 924 K--EKEKIPFILEGSLKAWKEE-QHRLA---------------EEERLREEKKAE-KKGK 964
E +++ S KAWKEE + RL EEE L+E+KK + ++ K
Sbjct: 1463 AWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWK 1522
Query: 965 EAGKKKGKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEESPHQPE 1012
+ + ++++ + ++ + +E S+E + K Q+VTEE H E
Sbjct: 1523 QVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQE 1570
Score = 35.8 bits (81), Expect = 0.48
Identities = 99/413 (23%), Positives = 171/413 (41%), Gaps = 69/413 (16%)
Query: 857 IQDWITKEEAIYQESKMN---EKII-----RTRAELELKSSANAKLTSASKIFSIK---- 904
++D + K++ + KM EK + R R EL++ A ++ K
Sbjct: 1919 VEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLV 1978
Query: 905 ESKSNKGISKT-EISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKKAEKKG 963
E K +T E S Q K + E+ F + SL EE+ L E+ L E+ KG
Sbjct: 1979 EGKETLSKGETPETSRQRKMTQVEQELFERKLSL----EEKILLHEDRILAMEESEIAKG 2034
Query: 964 K---EAGKK---KGKDNAEKEDSRSLKKK-SPYKEKSKEEQV--KIQEVT--EESPHQPE 1012
K G++ +G+ K + +KK+ S KE +K ++ +Q++T E Q E
Sbjct: 2035 KLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEE 2094
Query: 1013 PKITYPFHGYNMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFM 1072
K+T + I S + D + E T EK K R + + M
Sbjct: 2095 IKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEK-KLARKQRKLANKMRRM 2153
Query: 1073 IHLNDPKEIVKKEEK-----GDYYLEEEEEG--DEEQSLE------TEVSDAK--NKAFS 1117
I N +++ ++E K + L++EEEG +EE+ + + +AK +K
Sbjct: 2154 I--NKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKE 2211
Query: 1118 KFGS----------FSATLENGICLSISYYGSNGMAPEDKDPDLETILNIPSALTPTVVP 1167
KF S FS +E+ + + E+++ + E
Sbjct: 2212 KFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER------------EE 2259
Query: 1168 VIVTVPQSKAKGKIKGKEKPKESLKEEEHPKEEEKKEEEV-EPEPVLQETLDV 1219
V + + K + +G+EK E +EE+ K++EKK+EEV E E V +E ++
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEI 2312
Score = 31.6 bits (70), Expect = 9.1
Identities = 58/276 (21%), Positives = 111/276 (40%), Gaps = 47/276 (17%)
Query: 853 VAKSIQDWITKEEAIYQESKMNEKIIRTRAELELKSSANAKLTSASKIFSIKESKSNKGI 912
+AK+ + I K E++ +E KI++ A KLT + + +E K K
Sbjct: 2052 LAKASRKLIKKRESLSKEPAKLNKILK----------ALQKLTRDERKLTQEEIKMTKMK 2101
Query: 913 SKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEERLREEKK-AEKKGKEAGKKKG 971
+ ++ E+ K+ +K W + R E ++EKK A K+ K A K +
Sbjct: 2102 RALFVKERRLSIEQSKL------DIKEWDFSEKR---SELTKDEKKLARKQRKLANKMRR 2152
Query: 972 KDNAEK----EDSRSLKKKSPY-----KEKSKEEQVKIQEVTEESPHQPEPKITYPFHGY 1022
N E+ E+S+ +K S +E EE+ I + + E K
Sbjct: 2153 MINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAK-------- 2204
Query: 1023 NMGNIPTQISGSNYYLYPSDGGQIEVEKTMFEKGPTFIKVRVVKDNHNFMIHLNDPKEIV 1082
G+ P + + S ++E E+ E+ + + ++ + + +E
Sbjct: 2205 -RGDKPKE-------KFSSQVDEVESEEHFSEEMESLLDE--LEKQESLSSEEEEEREEE 2254
Query: 1083 KKEEKGDYYLEEEEEGDEEQSLETEVSDAKNKAFSK 1118
++ E+ + EEEE +EE+ E +V + + K
Sbjct: 2255 EEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK 2290
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,779,455
Number of Sequences: 37866
Number of extensions: 4459899
Number of successful extensions: 38082
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 713
Number of HSP's that attempted gapping in prelim test: 22342
Number of HSP's gapped (non-prelim): 11343
length of query: 2223
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2105
effective length of database: 13,779,330
effective search space: 29005489650
effective search space used: 29005489650
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.