Guide to the Human Genome
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Search of human proteins with 45592954

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45592954 cortexin 1 [Homo sapiens]
         (82 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45592954 cortexin 1 [Homo sapiens]                                 169   4e-43
gi|188497722 cortexin 3 [Homo sapiens]                                 75   1e-14
gi|115392142 cortexin 3 [Homo sapiens]                                 75   1e-14
gi|224586838 cortexin 2 [Homo sapiens]                                 69   8e-13
gi|239756833 PREDICTED: hypothetical protein [Homo sapiens]            30   0.41 
gi|239751318 PREDICTED: hypothetical protein XP_002347804 [Homo ...    30   0.41 
gi|239745817 PREDICTED: hypothetical protein XP_002343597 [Homo ...    30   0.41 
gi|116534898 desmoglein 2 preproprotein [Homo sapiens]                 28   2.1  
gi|126032338 ryanodine receptor 3 [Homo sapiens]                       28   2.1  
gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo s...    28   2.1  
gi|169215850 PREDICTED: transmembrane protein 46-like [Homo sapi...    27   4.6  
gi|113429443 PREDICTED: transmembrane protein 46-like [Homo sapi...    27   4.6  
gi|239743666 PREDICTED: hypothetical protein XP_002342940 isofor...    27   4.6  
gi|239743664 PREDICTED: hypothetical protein XP_002342939 isofor...    27   4.6  
gi|167466201 WAS protein family homolog 1 [Homo sapiens]               27   4.6  
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ...    26   6.0  
gi|4885197 ephrin A4 isoform a [Homo sapiens]                          26   6.0  
gi|239755085 PREDICTED: hypothetical protein [Homo sapiens]            26   7.8  
gi|169176429 PREDICTED: hypothetical protein [Homo sapiens]            26   7.8  
gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]                     26   7.8  
gi|18450371 protein tyrosine phosphatase, receptor type, A isofo...    26   7.8  
gi|18450369 protein tyrosine phosphatase, receptor type, A isofo...    26   7.8  
gi|28872814 semaphorin 4G [Homo sapiens]                               26   7.8  
gi|153792110 HEG homolog 1 [Homo sapiens]                              26   7.8  
gi|90991712 CD207 antigen, langerin [Homo sapiens]                     26   7.8  
gi|157694497 zinc finger and BTB domain containing 10 isoform b ...    26   7.8  
gi|157694499 zinc finger and BTB domain containing 10 isoform a ...    26   7.8  

>gi|45592954 cortexin 1 [Homo sapiens]
          Length = 82

 Score =  169 bits (428), Expect = 4e-43
 Identities = 82/82 (100%), Positives = 82/82 (100%)

Query: 1  MSATWTLSPEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRM 60
          MSATWTLSPEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRM
Sbjct: 1  MSATWTLSPEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRM 60

Query: 61 PASSWTDHKEALERGQFDYALV 82
          PASSWTDHKEALERGQFDYALV
Sbjct: 61 PASSWTDHKEALERGQFDYALV 82


>gi|188497722 cortexin 3 [Homo sapiens]
          Length = 81

 Score = 75.1 bits (183), Expect = 1e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)

Query: 9  PEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRMPASSWTDH 68
          P  L P       + +  EQ+  F FV+ L + L +L+VRC RILLDPY  MP S+W D 
Sbjct: 8  PSSLVPLGNESADSSMSLEQKMTFVFVILLFIFLGILIVRCFRILLDPYRSMPTSTWADG 67

Query: 69 KEALERGQFDYAL 81
           E LE+GQFD+AL
Sbjct: 68 LEGLEKGQFDHAL 80


>gi|115392142 cortexin 3 [Homo sapiens]
          Length = 81

 Score = 75.1 bits (183), Expect = 1e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)

Query: 9  PEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRMPASSWTDH 68
          P  L P       + +  EQ+  F FV+ L + L +L+VRC RILLDPY  MP S+W D 
Sbjct: 8  PSSLVPLGNESADSSMSLEQKMTFVFVILLFIFLGILIVRCFRILLDPYRSMPTSTWADG 67

Query: 69 KEALERGQFDYAL 81
           E LE+GQFD+AL
Sbjct: 68 LEGLEKGQFDHAL 80


>gi|224586838 cortexin 2 [Homo sapiens]
          Length = 81

 Score = 68.9 bits (167), Expect = 8e-13
 Identities = 32/58 (55%), Positives = 42/58 (72%)

Query: 24 LDAEQRTVFAFVLCLLVVLVLLMVRCVRILLDPYSRMPASSWTDHKEALERGQFDYAL 81
          L  EQ+T FAFV  L + L LL++RC +ILLDPYS MP+S+W D  E  ++G F+YAL
Sbjct: 23 LTLEQKTGFAFVGILCIFLGLLIIRCFKILLDPYSSMPSSTWEDEVEEFDKGTFEYAL 80


>gi|239756833 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 281

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 14/23 (60%), Positives = 14/23 (60%)

Query: 13 PPSTGPPVGAGLDAEQRTVFAFV 35
          PP TGP VGAG   EQR V   V
Sbjct: 57 PPETGPRVGAGSHLEQRVVQVLV 79


>gi|239751318 PREDICTED: hypothetical protein XP_002347804 [Homo
           sapiens]
          Length = 346

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 14/23 (60%), Positives = 14/23 (60%)

Query: 13  PPSTGPPVGAGLDAEQRTVFAFV 35
           PP TGP VGAG   EQR V   V
Sbjct: 122 PPETGPRVGAGSHLEQRVVQVLV 144


>gi|239745817 PREDICTED: hypothetical protein XP_002343597 [Homo
           sapiens]
          Length = 346

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 14/23 (60%), Positives = 14/23 (60%)

Query: 13  PPSTGPPVGAGLDAEQRTVFAFV 35
           PP TGP VGAG   EQR V   V
Sbjct: 122 PPETGPRVGAGSHLEQRVVQVLV 144


>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
          Length = 1118

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 15/30 (50%), Positives = 18/30 (60%)

Query: 20  VGAGLDAEQRTVFAFVLCLLVVLVLLMVRC 49
           VG G  A    + AF+L LLV L+LLM  C
Sbjct: 608 VGLGPAAIALMILAFLLLLLVPLLLLMCHC 637


>gi|126032338 ryanodine receptor 3 [Homo sapiens]
          Length = 4870

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 11/18 (61%), Positives = 12/18 (66%)

Query: 1    MSATWTLSPEPLPPSTGP 18
            +S  W   PE LPPSTGP
Sbjct: 3142 LSYWWERGPENLPPSTGP 3159


>gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo
           sapiens]
          Length = 348

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 18/69 (26%)

Query: 3   ATWTLS---------------PEPLPPSTGPP---VGAGLDAEQRTVFAFVLCLLVVLVL 44
           ATWT+                PE L  S GP    VG    +E  T F F+ C +V L L
Sbjct: 156 ATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSL 215

Query: 45  LMVRCVRIL 53
           +     ++L
Sbjct: 216 ICFSYTQLL 224


>gi|169215850 PREDICTED: transmembrane protein 46-like [Homo
           sapiens]
          Length = 547

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 9/12 (75%), Positives = 11/12 (91%)

Query: 10  EPLPPSTGPPVG 21
           EPLPP+ GPP+G
Sbjct: 190 EPLPPTLGPPLG 201


>gi|113429443 PREDICTED: transmembrane protein 46-like [Homo
           sapiens]
          Length = 492

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 9/12 (75%), Positives = 11/12 (91%)

Query: 10  EPLPPSTGPPVG 21
           EPLPP+ GPP+G
Sbjct: 190 EPLPPTLGPPLG 201


>gi|239743666 PREDICTED: hypothetical protein XP_002342940 isoform 2
           [Homo sapiens]
          Length = 465

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 8   SPEPLPPSTGPPVGAG 23
           S  PLPPST  PVG G
Sbjct: 319 SAPPLPPSTAAPVGQG 334


>gi|239743664 PREDICTED: hypothetical protein XP_002342939 isoform 1
           [Homo sapiens]
          Length = 482

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 8   SPEPLPPSTGPPVGAG 23
           S  PLPPST  PVG G
Sbjct: 336 SAPPLPPSTAAPVGQG 351


>gi|167466201 WAS protein family homolog 1 [Homo sapiens]
          Length = 465

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 8   SPEPLPPSTGPPVGAG 23
           S  PLPPST  PVG G
Sbjct: 319 SAPPLPPSTAAPVGQG 334


>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2
           [Homo sapiens]
          Length = 910

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 14/44 (31%), Positives = 17/44 (38%)

Query: 6   TLSPEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVLLMVRC 49
           T  P P P S GPP+G     E+ T        +   V   V C
Sbjct: 130 TAPPPPSPASPGPPLGPEGGEEETTTTIITTTTVTTTVTSPVLC 173


>gi|4885197 ephrin A4 isoform a [Homo sapiens]
          Length = 201

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 11/18 (61%), Positives = 17/18 (94%)

Query: 36  LCLLVVLVLLMVRCVRIL 53
           LCLL++L+LL++R +RIL
Sbjct: 184 LCLLLLLLLLILRLLRIL 201


>gi|239755085 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 310

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 6/31 (19%)

Query: 9   PEPLPPSTG------PPVGAGLDAEQRTVFA 33
           P PLPP TG      P VG GL + ++ V +
Sbjct: 72  PCPLPPDTGAPLGVLPAVGCGLPSRKKPVLS 102


>gi|169176429 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 310

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 6/31 (19%)

Query: 9   PEPLPPSTG------PPVGAGLDAEQRTVFA 33
           P PLPP TG      P VG GL + ++ V +
Sbjct: 72  PCPLPPDTGAPLGVLPAVGCGLPSRKKPVLS 102


>gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]
          Length = 1503

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 4/43 (9%)

Query: 18 PPVGAGLD---AEQRTVFAFV-LCLLVVLVLLMVRCVRILLDP 56
          P  GAG     AE  + F  + +C L++L++L+  CV    DP
Sbjct: 30 PQTGAGEAPPAAEVSSSFVILCVCSLIILIVLIANCVSCCKDP 72


>gi|18450371 protein tyrosine phosphatase, receptor type, A isoform
           2 precursor [Homo sapiens]
          Length = 793

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 14/47 (29%), Positives = 27/47 (57%), Gaps = 4/47 (8%)

Query: 2   SATWTLSPEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVLLMVR 48
           S+T   +PE  PPS   P+ A + A    + + ++ + +++VL M+R
Sbjct: 125 SSTAATTPETFPPSDETPIIAVMVA----LSSLLVIVFIIIVLYMLR 167


>gi|18450369 protein tyrosine phosphatase, receptor type, A isoform
           2 precursor [Homo sapiens]
          Length = 793

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 14/47 (29%), Positives = 27/47 (57%), Gaps = 4/47 (8%)

Query: 2   SATWTLSPEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVLLMVR 48
           S+T   +PE  PPS   P+ A + A    + + ++ + +++VL M+R
Sbjct: 125 SSTAATTPETFPPSDETPIIAVMVA----LSSLLVIVFIIIVLYMLR 167


>gi|28872814 semaphorin 4G [Homo sapiens]
          Length = 843

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 10/59 (16%)

Query: 3   ATWTLSPEPLPPSTGPPV----GAGLDAEQRTVFAFV------LCLLVVLVLLMVRCVR 51
           A+++L+  P  P+  P      GA L  + R ++         LCL++   LL V C+R
Sbjct: 649 ASYSLTVRPATPAPAPKAPATPGAQLAPDVRLLYVLAIAALGGLCLILASSLLYVACLR 707


>gi|153792110 HEG homolog 1 [Homo sapiens]
          Length = 1381

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 12/30 (40%), Positives = 14/30 (46%)

Query: 2   SATWTLSPEPLPPSTGPPVGAGLDAEQRTV 31
           S  W+ SP PLP S      A L   Q T+
Sbjct: 709 STPWSSSPSPLPVSLTTSTSAPLSVSQTTL 738


>gi|90991712 CD207 antigen, langerin [Homo sapiens]
          Length = 328

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 3/38 (7%)

Query: 6  TLSPEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLV 43
          +L P   PP +GP +  G   +  TV A ++CL +VLV
Sbjct: 20 SLWPREPPPKSGPSLVPG---KTPTVRAALICLTLVLV 54


>gi|157694497 zinc finger and BTB domain containing 10 isoform b
          [Homo sapiens]
          Length = 847

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 10/19 (52%), Positives = 11/19 (57%)

Query: 9  PEPLPPSTGPPVGAGLDAE 27
          P P PP+  PP G G D E
Sbjct: 48 PPPAPPALQPPNGRGADEE 66


>gi|157694499 zinc finger and BTB domain containing 10 isoform a
          [Homo sapiens]
          Length = 871

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 10/19 (52%), Positives = 11/19 (57%)

Query: 9  PEPLPPSTGPPVGAGLDAE 27
          P P PP+  PP G G D E
Sbjct: 48 PPPAPPALQPPNGRGADEE 66


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,845,654
Number of Sequences: 37866
Number of extensions: 147270
Number of successful extensions: 1191
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1170
Number of HSP's gapped (non-prelim): 29
length of query: 82
length of database: 18,247,518
effective HSP length: 54
effective length of query: 28
effective length of database: 16,202,754
effective search space: 453677112
effective search space used: 453677112
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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