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Search of human proteins with 13129006
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13129006 nucleolar protein GU2 [Homo sapiens]
(737 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13129006 nucleolar protein GU2 [Homo sapiens] 1463 0.0
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 818 0.0
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 206 6e-53
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 206 6e-53
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 197 3e-50
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 196 8e-50
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 196 8e-50
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 196 8e-50
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 196 8e-50
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 194 2e-49
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 191 2e-48
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 185 1e-46
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 185 1e-46
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 185 1e-46
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 182 1e-45
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 182 1e-45
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 182 1e-45
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 181 2e-45
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 181 2e-45
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 180 4e-45
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 179 1e-44
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 178 1e-44
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 177 2e-44
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 176 9e-44
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 169 8e-42
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 169 8e-42
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 166 6e-41
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 166 7e-41
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 157 4e-38
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi... 154 3e-37
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 1463 bits (3787), Expect = 0.0
Identities = 737/737 (100%), Positives = 737/737 (100%)
Query: 1 MPGKLLWGDIMELEAPLEESESQKKERQKSDRRKSRHHYDSDEKSETRENGVTDDLDAPK 60
MPGKLLWGDIMELEAPLEESESQKKERQKSDRRKSRHHYDSDEKSETRENGVTDDLDAPK
Sbjct: 1 MPGKLLWGDIMELEAPLEESESQKKERQKSDRRKSRHHYDSDEKSETRENGVTDDLDAPK 60
Query: 61 AKKSKMKEKLNGDTEEGFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHK 120
AKKSKMKEKLNGDTEEGFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHK
Sbjct: 61 AKKSKMKEKLNGDTEEGFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHK 120
Query: 121 SSDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQ 180
SSDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQ
Sbjct: 121 SSDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQ 180
Query: 181 ARTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV 240
ARTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV
Sbjct: 181 ARTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV 240
Query: 241 ACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGF 300
ACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGF
Sbjct: 241 ACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGF 300
Query: 301 AEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAAT 360
AEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAAT
Sbjct: 301 AEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAAT 360
Query: 361 TVEHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNAQCLHG 420
TVEHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNAQCLHG
Sbjct: 361 TVEHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNAQCLHG 420
Query: 421 DIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTG 480
DIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTG
Sbjct: 421 DIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTG 480
Query: 481 RAGRTGICICFYQPRERGQLRYVEQKAGITFKRVGVPSTMDLVKSKSMDAIRSLASVSYA 540
RAGRTGICICFYQPRERGQLRYVEQKAGITFKRVGVPSTMDLVKSKSMDAIRSLASVSYA
Sbjct: 481 RAGRTGICICFYQPRERGQLRYVEQKAGITFKRVGVPSTMDLVKSKSMDAIRSLASVSYA 540
Query: 541 AVDFFRPSAQRLIEEKGAVDALAAALAHISGASSFEPRSLITSDKGFVTMTLESLEEIQD 600
AVDFFRPSAQRLIEEKGAVDALAAALAHISGASSFEPRSLITSDKGFVTMTLESLEEIQD
Sbjct: 541 AVDFFRPSAQRLIEEKGAVDALAAALAHISGASSFEPRSLITSDKGFVTMTLESLEEIQD 600
Query: 601 VSCAWKELNRKLSSNAVSQITRMCLLKGNMGVCFDVPTTESERLQAEWHDSDWILSVPAK 660
VSCAWKELNRKLSSNAVSQITRMCLLKGNMGVCFDVPTTESERLQAEWHDSDWILSVPAK
Sbjct: 601 VSCAWKELNRKLSSNAVSQITRMCLLKGNMGVCFDVPTTESERLQAEWHDSDWILSVPAK 660
Query: 661 LPEIEEYYDGNTSSNSRQRSGWSSGRSGRSGRSGGRSGGRSGRQSRQGSRSGSRQDGRRR 720
LPEIEEYYDGNTSSNSRQRSGWSSGRSGRSGRSGGRSGGRSGRQSRQGSRSGSRQDGRRR
Sbjct: 661 LPEIEEYYDGNTSSNSRQRSGWSSGRSGRSGRSGGRSGGRSGRQSRQGSRSGSRQDGRRR 720
Query: 721 SGNRNRSRSGGHKRSFD 737
SGNRNRSRSGGHKRSFD
Sbjct: 721 SGNRNRSRSGGHKRSFD 737
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 818 bits (2112), Expect = 0.0
Identities = 435/720 (60%), Positives = 521/720 (72%), Gaps = 34/720 (4%)
Query: 20 SESQKKERQKSDRRKSRHHYDSDEKSETRENGVTDDLDAPKAKKSKMKEKLNGDTEEGFN 79
S K R+K + + + +K E +++DAPK KK K ++++NG+T E
Sbjct: 89 SPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEEIDAPKPKKMKKEKEMNGETREKSP 148
Query: 80 RLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKSSDNKLEETLTREQKEGAF 139
+L + F P D + E S+ S++++E+ + EQKEGAF
Sbjct: 149 KLKNGFPH---------PEPDCNPSEAASEE-----------SNSEIEQEIPVEQKEGAF 188
Query: 140 SNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERL 199
SNFPISEETIKLLKGRGVT+LFPIQ KTF VY GKDLIAQARTGTGKTFSFAIPLIE+L
Sbjct: 189 SNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKL 248
Query: 200 QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSVACFYGGTSYQSQINHIRNG 259
+ K+ R+P+VLVLAPTRELANQV+KDF DIT+KLSVACFYGGT Y Q +RNG
Sbjct: 249 HGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNG 308
Query: 260 IDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDN 319
IDILVGTPGRIKDH+Q+G+LDL+KL+HVVLDEVDQMLD+GFA+QVE+I+ +YK DSEDN
Sbjct: 309 IDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDN 368
Query: 320 PQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAVIG 379
PQTLLFSATCP WV+ VAKKYMKS YEQVDL+GK TQK A TVEHLAI+CHW+QR AVIG
Sbjct: 369 PQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIG 428
Query: 380 DVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNAQCLHGDIAQSQREITLKGFREGSF 439
DV++VYSG +GR IIFCETKK E++ N IKQ+AQ LHGDI Q QREITLKGFR GSF
Sbjct: 429 DVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSF 488
Query: 440 KVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPRERGQ 499
VLVATNVAARGLDIPEVDLVIQSSPP+DVESYIHRSGRTGRAGRTG+CICFYQ +E Q
Sbjct: 489 GVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQ 548
Query: 500 LRYVEQKAGITFKRVGVPSTMDLVKSKSMDAIRSLASVSYAAVDFFRPSAQRLIEEKGAV 559
L VEQKAGI FKR+GVPS +++K+ S DAIR L SV A+ F+ SA++LIEEKGAV
Sbjct: 549 LVQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHFKQSAEKLIEEKGAV 608
Query: 560 DALAAALAHISGASSFEPRSLITSDKGFVTMTLESLEEIQDVSCAWKELNRKLSSNAVSQ 619
+ALAAALAHISGA+S + RSLI S+ GFVTM L+ E+ ++S AWKEL +L S+
Sbjct: 609 EALAAALAHISGATSVDQRSLINSNVGFVTMILQCSIEMPNISYAWKELKEQLGEEIDSK 668
Query: 620 ITRMCLLKGNMGVCFDVPTTESERLQAEWHDS-DWILSVPAKLPEIEEYYDGNTSSNSRQ 678
+ M LKG +GVCFDVPT +Q +WHDS W LSV + PE+E +G
Sbjct: 669 VKGMVFLKGKLGVCFDVPTASVTEIQEKWHDSRRWQLSVATEQPELEGPREG-------- 720
Query: 679 RSGWSSGRSGRSGRSGGRSGGRSGRQSRQGSRS--GSRQDGRRRSGNRNRSRSGGHKRSF 736
G+ R G G G R G R R R+GSR G R G +S NRS++ G KRSF
Sbjct: 721 YGGFRGQREGSRGFRGQRDGNRRFRGQREGSRGPRGQRSGGGNKS---NRSQNKGQKRSF 777
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 206 bits (524), Expect = 6e-53
Identities = 124/366 (33%), Positives = 202/366 (55%), Gaps = 14/366 (3%)
Query: 140 SNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERL 199
+NFP + + +L + T PIQ + F G+D++ A+TG+GKT ++ +P I +
Sbjct: 176 ANFP--QYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHI 233
Query: 200 QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLSVACFYGGTSYQSQINHIR 257
+Q +++ P LVLAPTRELA QV + D + +L C YGG QI +
Sbjct: 234 N-HQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE 292
Query: 258 NGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSE 317
G++I + TPGR+ D L+SG+ +L + ++VLDE D+MLD+GF Q+ I+ +
Sbjct: 293 RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQI-----R 347
Query: 318 DNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAV 377
+ QTL++SAT P+ V ++A+ +++ Y Q++ VG + A + + C S++
Sbjct: 348 PDRQTLMWSATWPKEVRQLAEDFLRD-YTQIN-VGNLELSANHNILQIVDVCMESEKDHK 405
Query: 378 IGDVLQ-VYSGSEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQSQREITLKGFR 435
+ +++ + + E + IIF ETK+ ++ A C+HGD +Q +R+ L FR
Sbjct: 406 LIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFR 465
Query: 436 EGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPR 495
G +L+AT+VA+RGLD+ +V VI P E Y+HR GRT R+ G F+ P
Sbjct: 466 SGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPG 525
Query: 496 ERGQLR 501
Q R
Sbjct: 526 NLKQAR 531
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 206 bits (524), Expect = 6e-53
Identities = 124/366 (33%), Positives = 202/366 (55%), Gaps = 14/366 (3%)
Query: 140 SNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERL 199
+NFP + + +L + T PIQ + F G+D++ A+TG+GKT ++ +P I +
Sbjct: 176 ANFP--QYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHI 233
Query: 200 QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLSVACFYGGTSYQSQINHIR 257
+Q +++ P LVLAPTRELA QV + D + +L C YGG QI +
Sbjct: 234 N-HQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE 292
Query: 258 NGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSE 317
G++I + TPGR+ D L+SG+ +L + ++VLDE D+MLD+GF Q+ I+ +
Sbjct: 293 RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQI-----R 347
Query: 318 DNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAV 377
+ QTL++SAT P+ V ++A+ +++ Y Q++ VG + A + + C S++
Sbjct: 348 PDRQTLMWSATWPKEVRQLAEDFLRD-YTQIN-VGNLELSANHNILQIVDVCMESEKDHK 405
Query: 378 IGDVLQ-VYSGSEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQSQREITLKGFR 435
+ +++ + + E + IIF ETK+ ++ A C+HGD +Q +R+ L FR
Sbjct: 406 LIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFR 465
Query: 436 EGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPR 495
G +L+AT+VA+RGLD+ +V VI P E Y+HR GRT R+ G F+ P
Sbjct: 466 SGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPG 525
Query: 496 ERGQLR 501
Q R
Sbjct: 526 NLKQAR 531
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 197 bits (501), Expect = 3e-50
Identities = 120/365 (32%), Positives = 199/365 (54%), Gaps = 14/365 (3%)
Query: 140 SNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERL 199
+NFP + + ++ + T IQ + + G D++ A+TG+GKT S+ +P I +
Sbjct: 99 ANFPAN--VMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHI 156
Query: 200 QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLSVACFYGGTSYQSQINHIR 257
+Q +++ P LVLAPTRELA QV + + R +L C YGG QI +
Sbjct: 157 N-HQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLE 215
Query: 258 NGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSE 317
G++I + TPGR+ D L+ G+ +L + ++VLDE D+MLD+GF Q+ I+ +
Sbjct: 216 RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI-----R 270
Query: 318 DNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAV 377
+ QTL++SAT P+ V ++A+ ++K Y ++ +G + A + + CH ++
Sbjct: 271 PDRQTLMWSATWPKEVRQLAEDFLKD-YIHIN-IGALELSANHNILQIVDVCHDVEKDEK 328
Query: 378 IGDVLQ-VYSGSEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQSQREITLKGFR 435
+ +++ + S E + I+F ETK+ E+ A +HGD +Q +R+ L F+
Sbjct: 329 LIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFK 388
Query: 436 EGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPR 495
G +L+AT+VA+RGLD+ +V VI P E YIHR GRT R+ +TG F+ P
Sbjct: 389 HGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPN 448
Query: 496 ERGQL 500
Q+
Sbjct: 449 NIKQV 453
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 196 bits (497), Expect = 8e-50
Identities = 141/429 (32%), Positives = 227/429 (52%), Gaps = 30/429 (6%)
Query: 78 FNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDT----STHKSSDNKLEETLTRE 133
++++ +E K K++ DLP + Y K+S S++ S K + N + L
Sbjct: 173 WDQIREEGLKWQKTKWADLPPIKKNFY-KESTATSAMSKVEADSWRKENFNITWDDLKDG 231
Query: 134 QK----------EGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQART 183
+K + AF +P E ++ +K G PIQ + + V +G DLI A+T
Sbjct: 232 EKRPIPNPTCTFDDAFQCYP---EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQT 288
Query: 184 GTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRK-LSVAC 242
GTGKT + +P L + P +LVL PTRELA QV + + K L C
Sbjct: 289 GTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVC 348
Query: 243 FYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAE 302
YGG + QI ++ G+DI++ TPGR+ D S ++L + ++VLDE D+MLD+GF
Sbjct: 349 VYGGGNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEP 408
Query: 303 QVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTV 362
Q+ I+ D + QT++ SAT P V+++A+ Y+K + VG + A ++V
Sbjct: 409 QIMKIL-----LDVRPDRQTVMTSATWPHSVHRLAQSYLKE--PMIVYVGTLDLVAVSSV 461
Query: 363 EHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQN--AQCLHG 420
+ I ++ + + LQ S ++ + I+F ++K V + + I N + LHG
Sbjct: 462 KQNIIVTTEEEKWSHMQTFLQSMSSTD-KVIVFV-SRKAVADHLSSDLILGNISVESLHG 519
Query: 421 DIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTG 480
D Q RE L+ F+ G ++L+AT++A+RGLD+ +V V P+++E Y+HR GRTG
Sbjct: 520 DREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTG 579
Query: 481 RAGRTGICI 489
RAGRTG+ I
Sbjct: 580 RAGRTGVSI 588
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 196 bits (497), Expect = 8e-50
Identities = 123/343 (35%), Positives = 194/343 (56%), Gaps = 11/343 (3%)
Query: 156 GVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQET---IKKSRSP 212
G T L P+Q + + G+DL+A A+TG+GKT +F +P++ + + T K+ + P
Sbjct: 307 GYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEP 366
Query: 213 KVLVLAPTRELANQVAKDFKDITRKLSVAC--FYGGTSYQSQINHIRNGIDILVGTPGRI 270
+ +++APTREL NQ+ + + + V YGGT I I G +IL TPGR+
Sbjct: 367 ECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRL 426
Query: 271 KDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDNPQTLLFSATCP 330
D + ++ L +++++VLDE D+MLD+GF +++ +I S++ QTL+FSAT P
Sbjct: 427 MDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI-SCPGMPSKEQRQTLMFSATFP 485
Query: 331 QWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAVIGDVLQVYSGSEG 390
+ + ++A +++KS Y V VG++ A V+ +Q + + ++L+ + +
Sbjct: 486 EEIQRLAAEFLKSNYLFV-AVGQVGG-ACRDVQQTVLQVGQFSKREKLVEILR--NIGDE 541
Query: 391 RAIIFCETKKNVTEMA-MNPHIKQNAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAA 449
R ++F ETKK +A K + +HGD Q +RE L FR G VLVAT+VAA
Sbjct: 542 RTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAA 601
Query: 450 RGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFY 492
RGLDI V VI P ++ Y+HR GRTGR G TG I F+
Sbjct: 602 RGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFF 644
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 196 bits (497), Expect = 8e-50
Identities = 123/343 (35%), Positives = 194/343 (56%), Gaps = 11/343 (3%)
Query: 156 GVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQET---IKKSRSP 212
G T L P+Q + + G+DL+A A+TG+GKT +F +P++ + + T K+ + P
Sbjct: 307 GYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEP 366
Query: 213 KVLVLAPTRELANQVAKDFKDITRKLSVAC--FYGGTSYQSQINHIRNGIDILVGTPGRI 270
+ +++APTREL NQ+ + + + V YGGT I I G +IL TPGR+
Sbjct: 367 ECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRL 426
Query: 271 KDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDNPQTLLFSATCP 330
D + ++ L +++++VLDE D+MLD+GF +++ +I S++ QTL+FSAT P
Sbjct: 427 MDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI-SCPGMPSKEQRQTLMFSATFP 485
Query: 331 QWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAVIGDVLQVYSGSEG 390
+ + ++A +++KS Y V VG++ A V+ +Q + + ++L+ + +
Sbjct: 486 EEIQRLAAEFLKSNYLFV-AVGQVGG-ACRDVQQTVLQVGQFSKREKLVEILR--NIGDE 541
Query: 391 RAIIFCETKKNVTEMA-MNPHIKQNAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAA 449
R ++F ETKK +A K + +HGD Q +RE L FR G VLVAT+VAA
Sbjct: 542 RTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAA 601
Query: 450 RGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFY 492
RGLDI V VI P ++ Y+HR GRTGR G TG I F+
Sbjct: 602 RGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFF 644
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 196 bits (497), Expect = 8e-50
Identities = 123/343 (35%), Positives = 194/343 (56%), Gaps = 11/343 (3%)
Query: 156 GVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQET---IKKSRSP 212
G T L P+Q + + G+DL+A A+TG+GKT +F +P++ + + T K+ + P
Sbjct: 273 GYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEP 332
Query: 213 KVLVLAPTRELANQVAKDFKDITRKLSVAC--FYGGTSYQSQINHIRNGIDILVGTPGRI 270
+ +++APTREL NQ+ + + + V YGGT I I G +IL TPGR+
Sbjct: 333 ECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRL 392
Query: 271 KDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDNPQTLLFSATCP 330
D + ++ L +++++VLDE D+MLD+GF +++ +I S++ QTL+FSAT P
Sbjct: 393 MDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI-SCPGMPSKEQRQTLMFSATFP 451
Query: 331 QWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAVIGDVLQVYSGSEG 390
+ + ++A +++KS Y V VG++ A V+ +Q + + ++L+ + +
Sbjct: 452 EEIQRLAAEFLKSNYLFV-AVGQVGG-ACRDVQQTVLQVGQFSKREKLVEILR--NIGDE 507
Query: 391 RAIIFCETKKNVTEMA-MNPHIKQNAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAA 449
R ++F ETKK +A K + +HGD Q +RE L FR G VLVAT+VAA
Sbjct: 508 RTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAA 567
Query: 450 RGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFY 492
RGLDI V VI P ++ Y+HR GRTGR G TG I F+
Sbjct: 568 RGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFF 610
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 194 bits (494), Expect = 2e-49
Identities = 126/355 (35%), Positives = 201/355 (56%), Gaps = 18/355 (5%)
Query: 144 ISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQ 203
IS + + LK G PIQ + + G+DLI A+TG+GKT +F +P+ + +Q
Sbjct: 379 ISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIM-DQ 437
Query: 204 ETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLS--VACFYGGTSYQSQINHIRNGID 261
++++ P +++ PTRELA Q+ K+ K ++ L V C YGGT QI ++ G +
Sbjct: 438 RSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAE 497
Query: 262 ILVGTPGRIKDHL--QSGRL-DLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSED 318
I+V TPGR+ D L SGR+ +L ++ +VVLDE D+M D+GF QV I+ ++ + D
Sbjct: 498 IIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIV-DNVRPDR-- 554
Query: 319 NPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAVI 378
QT++FSAT P+ + +A++ + E V + G+ + VE I ++ +
Sbjct: 555 --QTVMFSATFPRAMEALARRILSKPIE-VQVGGRSV--VCSDVEQQVIVIEEEKKFLKL 609
Query: 379 GDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNAQC--LHGDIAQSQREITLKGFRE 436
++L Y S G IIF + +++ + + ++ + C LHG I Q R+ + F+
Sbjct: 610 LELLGHYQES-GSVIIFVDKQEHADGL-LKDLMRASYPCMSLHGGIDQYDRDSIINDFKN 667
Query: 437 GSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICF 491
G+ K+LVAT+VAARGLD+ + LV+ S P E Y+HR+GRTGRAG G F
Sbjct: 668 GTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTF 722
Score = 38.5 bits (88), Expect = 0.023
Identities = 27/65 (41%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 670 GNTSSNSRQRSGWSSGRSGRSGRSGGRSGGRSGRQSRQGSRSGSRQDGRRRSGNRNRSRS 729
G S + R+RS S GRSG RS S RS R + SRS R R RS +R++ RS
Sbjct: 2 GRESRHYRKRSA-SRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRS 60
Query: 730 GGHKR 734
R
Sbjct: 61 RSRDR 65
Score = 35.4 bits (80), Expect = 0.19
Identities = 23/54 (42%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 686 RSGRSGRSGGRSGGR--SGRQSRQGSRSGSRQDGRRRSGNRNRSRSGGHKRSFD 737
RS GRSG RS R S ++S++G SR R R R+RSR RS D
Sbjct: 11 RSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRD 64
Score = 33.9 bits (76), Expect = 0.56
Identities = 31/140 (22%), Positives = 64/140 (45%), Gaps = 17/140 (12%)
Query: 17 LEESESQKKERQKSDRRKSRHHYDSDEKSETRENGVTDDLDAPKAKKSKMKEKLNGDTEE 76
L S S++++R + +RR+SR +S +R K+KK++ + + T+
Sbjct: 68 LRRSRSRERDRSR-ERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDG 126
Query: 77 GFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKSSDNKLEETLTR---E 133
G +S K ++KD D+ ++K K + D + + K +E + + E
Sbjct: 127 G---------ESSKEKKKDKD----DKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREE 173
Query: 134 QKEGAFSNFPISEETIKLLK 153
Q++ A N ++ I+ +K
Sbjct: 174 QRKKAMENIGELKKEIEEMK 193
Score = 33.5 bits (75), Expect = 0.73
Identities = 23/55 (41%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 685 GRSGRSGRSGGRSGGRSGRQSRQGSRSG--SRQDGRRRSGNRNRSRSGGHKRSFD 737
GR R R S GRSG +SR S S S++ RRS +R+R R RS D
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRD 56
Score = 33.1 bits (74), Expect = 0.95
Identities = 32/138 (23%), Positives = 60/138 (43%), Gaps = 8/138 (5%)
Query: 20 SESQKKERQKSDRR-KSRHHYDSDEKSETRENGVTDDLDAPKAKKSKMKEKLNGDTEEGF 78
S S K+ ++ DRR +SR E+S +R+ + D + ++S+ +E+ + E
Sbjct: 26 SPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRER-DRSRERRR 84
Query: 79 NRLSDEFSKSHKSR----RKDLPNGDIDEYEKKSKRVSSLD--TSTHKSSDNKLEETLTR 132
+R D +SR R P + E +S+ D S+ + +K ++ +
Sbjct: 85 SRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEK 144
Query: 133 EQKEGAFSNFPISEETIK 150
E+ G F + EE K
Sbjct: 145 EKDAGNFDQNKLEEEMRK 162
Score = 31.6 bits (70), Expect = 2.8
Identities = 23/61 (37%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
Query: 673 SSNSRQRSGWSSGRSGRSGRSGGRSGGRSGRQSRQGSRSGSRQDGRRRSGNRNRSRSGGH 732
S + +R S R R RS R R R SR+ RS R+ R R R+RSRS G
Sbjct: 42 SRDRDRRRERSRSRDKRRSRSRDRKRLRRSR-SRERDRSRERRRSRSRDRRRSRSRSRGR 100
Query: 733 K 733
+
Sbjct: 101 R 101
Score = 30.4 bits (67), Expect = 6.2
Identities = 23/59 (38%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 676 SRQRSGWSSGRSGRSGRSGGRSGGRSGRQSRQGSRSGSRQDGRRRS-GNRNRSRSGGHK 733
SR R S R RS R + R+ SRS R+ R RS G R+RS S G+K
Sbjct: 52 SRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNK 110
Score = 30.4 bits (67), Expect = 6.2
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
Query: 674 SNSRQRSGWSSGRSGRSGRSGGRSGGRSGRQSR---QGSRSGSRQDGRRRSGNRNRSRS 729
S R+R S R R RS R R+SR +G RS S G + NRSRS
Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS 120
Score = 30.0 bits (66), Expect = 8.0
Identities = 28/81 (34%), Positives = 32/81 (39%), Gaps = 16/81 (19%)
Query: 670 GNTSSNSRQRSGWSSGRSGRSGRSGGRSGGRSGRQSRQGSR---------------SGSR 714
G + S SR RS S RS R RS R R+ R SR S SR
Sbjct: 16 GRSGSRSRSRSP-SDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSR 74
Query: 715 QDGRRRSGNRNRSRSGGHKRS 735
+ R R R+RSR RS
Sbjct: 75 ERDRSRERRRSRSRDRRRSRS 95
Score = 30.0 bits (66), Expect = 8.0
Identities = 25/69 (36%), Positives = 28/69 (40%), Gaps = 7/69 (10%)
Query: 673 SSNSRQRSGWSSGRSGRSGRSGGRSGGRSG-------RQSRQGSRSGSRQDGRRRSGNRN 725
S R S R R RS R RS R+SR R SR+ R RS +R
Sbjct: 32 SKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRR 91
Query: 726 RSRSGGHKR 734
RSRS R
Sbjct: 92 RSRSRSRGR 100
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 191 bits (485), Expect = 2e-48
Identities = 152/491 (30%), Positives = 249/491 (50%), Gaps = 43/491 (8%)
Query: 45 SETRENGVTDD-LDAPKAKKSKMKEKLNGDTEEGFNRLSDEFSKSHKSRRKDLPNGDIDE 103
SET+ G++ + + K KS K + + E + E K K +RK + + + D
Sbjct: 66 SETQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSNSESKKKKKKKRKMVNDAEPDT 125
Query: 104 YEKKSKRVSSLD---TSTHKSSDNKLEETLTREQKE----------GAFSNFP------- 143
+ K++ + T K ++N +E+ E + GAF +
Sbjct: 126 KKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNL 185
Query: 144 ISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQ 203
++E T+K +K G T + IQ K+ P+ EG+DL+A A+TG+GKT +F IP +E + + +
Sbjct: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 245
Query: 204 ETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKL--SVACFYGGTSYQSQINHIRNGID 261
+ VL+L+PTRELA Q K++ + GG++ ++ + NGI+
Sbjct: 246 FMPRNGTG--VLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGIN 303
Query: 262 ILVGTPGRIKDHLQSGRLDLSK-LRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDNP 320
I+V TPGR+ DH+Q+ + K L+ +V+DE D++LD+GF E+++ II
Sbjct: 304 IIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLL-----PTRR 358
Query: 321 QTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLA---IQCHWSQRPAV 377
QT+LFSAT + V +A+ +K ++ VG KA TV+ L + C +R +
Sbjct: 359 QTMLFSATQTRKVEDLARISLK---KEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLL 415
Query: 378 IGDVLQVYSGSEGRAIIFCETKKNVT-EMAMNPHIKQNAQCLHGDIAQSQREITLKGFRE 436
+ L+ + + ++F + +V + +I +HG Q++R T F
Sbjct: 416 LFTFLK--KNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCN 473
Query: 437 GSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRA--GRTGICICFYQP 494
L+ T+VAARGLDIPEVD ++Q PP D + YIHR GRT R GR G + +P
Sbjct: 474 ADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGR-GHALLILRP 532
Query: 495 RERGQLRYVEQ 505
E G LRY++Q
Sbjct: 533 EELGFLRYLKQ 543
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 185 bits (470), Expect = 1e-46
Identities = 118/379 (31%), Positives = 203/379 (53%), Gaps = 14/379 (3%)
Query: 120 KSSDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIA 179
KS + +L T K+ AF +P + +K + G+ PIQ + + + +G DLI
Sbjct: 209 KSGEKRLIPKPTCRFKD-AFQQYP---DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIV 264
Query: 180 QARTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRK-L 238
A+TGTGKT S+ +P L + ++ P +LVL PTRELA V + + K L
Sbjct: 265 VAQTGTGKTLSYLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSYKGL 324
Query: 239 SVACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDL 298
C YGG + QI I G+DI++ TPGR+ D + ++L + ++V+DE D+MLD+
Sbjct: 325 KSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDM 384
Query: 299 GFAEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKA 358
F Q+ I+ D + QT++ SAT P V ++A Y+K + VG + A
Sbjct: 385 EFEPQIRKIL-----LDVRPDRQTVMTSATWPDTVRQLALSYLKD--PMIVYVGNLNLVA 437
Query: 359 ATTVEHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQ-NAQC 417
TV+ I ++ A+ + ++ S ++ + I+F K +++ + +I+ +A+
Sbjct: 438 VNTVKQNIIVTTEKEKRALTQEFVENMSPND-KVIMFVSQKHIADDLSSDFNIQGISAES 496
Query: 418 LHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSG 477
LHG+ QS +E ++ F+ G+ K+L+ T++ +RGLD+ +V V P++++ Y+HR G
Sbjct: 497 LHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVG 556
Query: 478 RTGRAGRTGICICFYQPRE 496
GR G+TG + R+
Sbjct: 557 YIGRTGKTGTSVTLITQRD 575
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 185 bits (470), Expect = 1e-46
Identities = 119/373 (31%), Positives = 201/373 (53%), Gaps = 23/373 (6%)
Query: 138 AFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIE 197
+F + +SE ++ + G IQ + P +G D+IAQA++GTGKT +FAI +++
Sbjct: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92
Query: 198 RLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSVACF--YGGTSYQSQINH 255
+++ + ++ + LVLAPTRELA Q+ K + + +C GGT+ ++++
Sbjct: 93 QIELDL------KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQK 146
Query: 256 IR-NGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKT 314
++ I+VGTPGR+ D L L ++ VLDE D+ML GF +Q+ DI +
Sbjct: 147 LQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKL--- 203
Query: 315 DSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLA-IQCHWSQ 373
N Q +L SAT P V +V KK+M+ D + + +K T+E + + +
Sbjct: 204 --NSNTQVVLLSATMPSDVLEVTKKFMR------DPIRILVKKEELTLEGIRQFYINVER 255
Query: 374 RPAVIGDVLQVYSG-SEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQSQREITL 431
+ + +Y + +A+IF T++ V + H + +HGD+ Q +R++ +
Sbjct: 256 EEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIM 315
Query: 432 KGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICF 491
+ FR GS +VL+ T++ ARG+D+ +V LVI P + E+YIHR GR GR GR G+ I
Sbjct: 316 REFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINM 375
Query: 492 YQPRERGQLRYVE 504
++ LR +E
Sbjct: 376 VTEEDKRTLRDIE 388
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 185 bits (469), Expect = 1e-46
Identities = 119/376 (31%), Positives = 194/376 (51%), Gaps = 26/376 (6%)
Query: 138 AFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIE 197
+FS+ + E + ++ T P+Q + E +DL+A A+TG+GKT +F +P++
Sbjct: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240
Query: 198 RL------------QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV--ACF 243
++ + N ++ + P LVLAPTRELA Q+ ++ + + + V
Sbjct: 241 QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 300
Query: 244 YGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQ 303
YGG QI + G +LV TPGR+ D ++ G++ L +++VLDE D+MLD+GF Q
Sbjct: 301 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 360
Query: 304 VEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVE 363
+ I+ + + T++FSAT P+ + +A+ ++ + + + +T E
Sbjct: 361 IRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIFLAVGRVGSTSE 413
Query: 364 HLAIQCHW---SQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMA-MNPHIKQNAQCLH 419
++ + W S + + + D+L +G + ++F ETKK + H +H
Sbjct: 414 NITQKVVWVEESDKRSFLLDLLNA-TGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIH 472
Query: 420 GDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRT 479
GD +Q RE L FR G +LVAT VAARGLDI V VI P D+E Y+HR GRT
Sbjct: 473 GDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRT 532
Query: 480 GRAGRTGICICFYQPR 495
GR G G+ F+ R
Sbjct: 533 GRVGNLGLATSFFNER 548
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 182 bits (462), Expect = 1e-45
Identities = 141/491 (28%), Positives = 236/491 (48%), Gaps = 60/491 (12%)
Query: 28 QKSDRRKSRHHYDSDEKSETRENGVTDDLDAPKAKKSKMKEKLNGDTEEGFNRLSDEFSK 87
++ R +SR + D EK T E ++ K +K + K++ +
Sbjct: 310 KQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQR---------------WDD 354
Query: 88 SHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKSSDNKLEETLTREQKEGAFSNFPISEE 147
H S++K +DE + R+ D S + K+ + R K+ + +
Sbjct: 355 RHWSQKK------LDEMTDRDWRIFREDYSI-TTKGGKIPNPI-RSWKDSS-----LPPH 401
Query: 148 TIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPL---IERLQRNQE 204
++++ G PIQ + + +D+I A TG+GKT +F IPL I L +
Sbjct: 402 ILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDR 461
Query: 205 TIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV--ACFYGGTSYQSQINHIRNGIDI 262
+ + P ++LAPTRELA Q+ ++ + L + GG S + Q +R G +I
Sbjct: 462 IEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEI 521
Query: 263 LVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDII------HESYKTDS 316
++ TPGR+ D L++ L LS+ +VVLDE D+M+D+GF V+ I+ ++ TD
Sbjct: 522 VIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDE 581
Query: 317 EDNP---------------QTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATT 361
++P QT++F+AT P V ++A+ Y+ R V +G +
Sbjct: 582 AEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYL--RRPAVVYIGSAGKPHERV 639
Query: 362 VEHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMN-PHIKQNAQCLHG 420
+ + + +R ++ + Q G + IIF KK +A + + NA LHG
Sbjct: 640 EQKVFLMSESEKRKKLLAILEQ---GFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHG 696
Query: 421 DIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTG 480
Q QRE L + G+ +LVAT+VA RG+DI +V +V+ +++E YIHR GRTG
Sbjct: 697 GKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTG 756
Query: 481 RAGRTGICICF 491
RAG++G+ I F
Sbjct: 757 RAGKSGVAITF 767
Score = 31.2 bits (69), Expect = 3.6
Identities = 13/48 (27%), Positives = 28/48 (58%)
Query: 7 WGDIMELEAPLEESESQKKERQKSDRRKSRHHYDSDEKSETRENGVTD 54
+GD+ME LEE E ++ +K +++++ +D S+ + + +TD
Sbjct: 320 YGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTD 367
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 182 bits (461), Expect = 1e-45
Identities = 120/376 (31%), Positives = 196/376 (52%), Gaps = 28/376 (7%)
Query: 139 FSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGK-DLIAQARTGTGKTFSFAIPLIE 197
FS+ + E + ++ T P+Q P+ +GK DL+A A+TG+GKT +F +P++
Sbjct: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAI-PIIKGKRDLMACAQTGSGKTAAFLLPILS 238
Query: 198 RL------------QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV--ACF 243
++ + N ++ + P LVLAPTRELA Q+ ++ + + + V
Sbjct: 239 QIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 298
Query: 244 YGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQ 303
YGG QI + G +LV TPGR+ D ++ G++ L +++VLDE D+MLD+GF Q
Sbjct: 299 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 358
Query: 304 VEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVE 363
+ I+ + + T++FSAT P+ + +A+ ++ + + + +T E
Sbjct: 359 IRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIFLAVGRVGSTSE 411
Query: 364 HLAIQCHWSQ---RPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMA-MNPHIKQNAQCLH 419
++ + W + + + + D+L +GS+ ++F ETKK + H +H
Sbjct: 412 NITQKVVWVEDLDKRSFLLDILGA-TGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIH 470
Query: 420 GDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRT 479
GD +Q RE L FR G +LVAT VAARGLDI V VI P D+E Y+HR GRT
Sbjct: 471 GDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRT 530
Query: 480 GRAGRTGICICFYQPR 495
GR G G+ F+ +
Sbjct: 531 GRVGNLGLATSFFNEK 546
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 182 bits (461), Expect = 1e-45
Identities = 120/376 (31%), Positives = 196/376 (52%), Gaps = 28/376 (7%)
Query: 139 FSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGK-DLIAQARTGTGKTFSFAIPLIE 197
FS+ + E + ++ T P+Q P+ +GK DL+A A+TG+GKT +F +P++
Sbjct: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAI-PIIKGKRDLMACAQTGSGKTAAFLLPILS 238
Query: 198 RL------------QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV--ACF 243
++ + N ++ + P LVLAPTRELA Q+ ++ + + + V
Sbjct: 239 QIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 298
Query: 244 YGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQ 303
YGG QI + G +LV TPGR+ D ++ G++ L +++VLDE D+MLD+GF Q
Sbjct: 299 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 358
Query: 304 VEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVE 363
+ I+ + + T++FSAT P+ + +A+ ++ + + + +T E
Sbjct: 359 IRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIFLAVGRVGSTSE 411
Query: 364 HLAIQCHWSQ---RPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMA-MNPHIKQNAQCLH 419
++ + W + + + + D+L +GS+ ++F ETKK + H +H
Sbjct: 412 NITQKVVWVEDLDKRSFLLDILGA-TGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIH 470
Query: 420 GDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRT 479
GD +Q RE L FR G +LVAT VAARGLDI V VI P D+E Y+HR GRT
Sbjct: 471 GDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRT 530
Query: 480 GRAGRTGICICFYQPR 495
GR G G+ F+ +
Sbjct: 531 GRVGNLGLATSFFNEK 546
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 181 bits (459), Expect = 2e-45
Identities = 147/505 (29%), Positives = 237/505 (46%), Gaps = 57/505 (11%)
Query: 17 LEESESQKK-------ERQKSDRRKSRHHYDSDEKS-----ETRENGVTDDLDA-PKAKK 63
LEE + ++K + ++ D +++ Y ++ + E E+ + D D P A
Sbjct: 134 LEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPT 193
Query: 64 SKMKEKLN--GDTEEGFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKS 121
K+ + L +E + F H+ P ID K + RVS S
Sbjct: 194 KKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGS 253
Query: 122 SDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQA 181
S F++F E+ + ++ T PIQ + G+D+I A
Sbjct: 254 S----------------FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIA 297
Query: 182 RTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLS 239
+TG+GKT +F P++ + +Q+ ++ P +++ PTREL Q+ + K + L
Sbjct: 298 KTGSGKTAAFIWPMLIHIM-DQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLR 356
Query: 240 VACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLG 299
YGG S Q ++ G +I+V TPGR+ DH++ +L ++ ++V DE D+M D+G
Sbjct: 357 SVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMG 416
Query: 300 FAEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKS--RYEQVDLVGKMTQK 357
F QV I + + QTLLFSAT + + K+A+ + R Q D +G+ +
Sbjct: 417 FEYQVRSIA-----SHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGD-IGEANED 470
Query: 358 AATTVEHL---AIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQ- 413
VE L + +W R V S G ++F K N E+A N +KQ
Sbjct: 471 VTQIVEILHSGPSKWNWLTRRLV-------EFTSSGSVLLFVTKKANAEELANN--LKQE 521
Query: 414 --NAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVES 471
N LHGD+ QS+R + F++ VLVAT+VAARGLDIP + VI +D+++
Sbjct: 522 GHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDT 581
Query: 472 YIHRSGRTGRAGRTGICICFYQPRE 496
+ HR GRTGRAG G+ P++
Sbjct: 582 HTHRIGRTGRAGEKGVAYTLLTPKD 606
Score = 34.7 bits (78), Expect = 0.33
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 21/119 (17%)
Query: 635 DVPTTESERLQAEWHDSDWILSVPAKLPEIEEYYDGNTSS--NSRQRSGWSSGRSGR--- 689
D P T + + + ++ I P P NT+S NSR+ +G S+G+ R
Sbjct: 753 DSPVTSAAKGIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRERYTE 812
Query: 690 --------SGRSGGR--------SGGRSGRQSRQGSRSGSRQDGRRRSGNRNRSRSGGH 732
G +G R GGR G R S DG R NR+ +G H
Sbjct: 813 NRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESSSRHTDGHRHGENRHGGSAGRH 871
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 181 bits (459), Expect = 2e-45
Identities = 147/505 (29%), Positives = 237/505 (46%), Gaps = 57/505 (11%)
Query: 17 LEESESQKK-------ERQKSDRRKSRHHYDSDEKS-----ETRENGVTDDLDA-PKAKK 63
LEE + ++K + ++ D +++ Y ++ + E E+ + D D P A
Sbjct: 134 LEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPT 193
Query: 64 SKMKEKLN--GDTEEGFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKS 121
K+ + L +E + F H+ P ID K + RVS S
Sbjct: 194 KKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGS 253
Query: 122 SDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQA 181
S F++F E+ + ++ T PIQ + G+D+I A
Sbjct: 254 S----------------FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIA 297
Query: 182 RTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLS 239
+TG+GKT +F P++ + +Q+ ++ P +++ PTREL Q+ + K + L
Sbjct: 298 KTGSGKTAAFIWPMLIHIM-DQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLR 356
Query: 240 VACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLG 299
YGG S Q ++ G +I+V TPGR+ DH++ +L ++ ++V DE D+M D+G
Sbjct: 357 SVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMG 416
Query: 300 FAEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKS--RYEQVDLVGKMTQK 357
F QV I + + QTLLFSAT + + K+A+ + R Q D +G+ +
Sbjct: 417 FEYQVRSIA-----SHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGD-IGEANED 470
Query: 358 AATTVEHL---AIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQ- 413
VE L + +W R V S G ++F K N E+A N +KQ
Sbjct: 471 VTQIVEILHSGPSKWNWLTRRLV-------EFTSSGSVLLFVTKKANAEELANN--LKQE 521
Query: 414 --NAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVES 471
N LHGD+ QS+R + F++ VLVAT+VAARGLDIP + VI +D+++
Sbjct: 522 GHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDT 581
Query: 472 YIHRSGRTGRAGRTGICICFYQPRE 496
+ HR GRTGRAG G+ P++
Sbjct: 582 HTHRIGRTGRAGEKGVAYTLLTPKD 606
Score = 34.7 bits (78), Expect = 0.33
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 21/119 (17%)
Query: 635 DVPTTESERLQAEWHDSDWILSVPAKLPEIEEYYDGNTSS--NSRQRSGWSSGRSGR--- 689
D P T + + + ++ I P P NT+S NSR+ +G S+G+ R
Sbjct: 753 DSPVTSAAKGIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRERYTE 812
Query: 690 --------SGRSGGR--------SGGRSGRQSRQGSRSGSRQDGRRRSGNRNRSRSGGH 732
G +G R GGR G R S DG R NR+ +G H
Sbjct: 813 NRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESSSRHTDGHRHGENRHGGSAGRH 871
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 180 bits (457), Expect = 4e-45
Identities = 168/541 (31%), Positives = 245/541 (45%), Gaps = 60/541 (11%)
Query: 30 SDRRKSRHHYDSDEKSE-TRENGVTDDLDAPKAKKSKMKEKLNGDTEEGFNRL--SDEFS 86
S +K R DEK E R+ T+D +A K K KE G + L +DE
Sbjct: 106 SQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEG 165
Query: 87 KSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKSSDNKLEET------LTREQKEGAFS 140
++ D + D E + +L K K +E ++ + +F
Sbjct: 166 SEDEASETDYSSAD----ENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENLSFQ 221
Query: 141 NFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQ 200
+ +S +K + G PIQ GKD+ A A TGTGKT +FA+P++ERL
Sbjct: 222 DMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERL- 280
Query: 201 RNQETIKKSRSP--KVLVLAPTRELANQVAKDFKDITRKLSVAC------FYGGTSYQSQ 252
K ++P +VLVL PTREL QV +TR+L+ C GG +SQ
Sbjct: 281 ----IYKPRQAPVTRVLVLVPTRELGIQV----HSVTRQLAQFCNITTCLAVGGLDVKSQ 332
Query: 253 INHIRNGIDILVGTPGRIKDHLQS-GRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHES 311
+R DIL+ TPGR+ DHL + LS + ++LDE D+MLD F EQ+++II
Sbjct: 333 EAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMC 392
Query: 312 YKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHW 371
+ QT+LFSAT V +A +K+ ++ + T V Q
Sbjct: 393 -----SHHRQTMLFSATMTDEVKDLASVSLKNPV-------RIFVNSNTDVAPFLRQEFI 440
Query: 372 SQRPAVIGDVLQVYSGSEGRA-----IIFCETKKNVTEMAMNPHIKQNAQCL-----HGD 421
RP GD + + R ++F +TKK M HI L HG+
Sbjct: 441 RIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRM----HILLGLMGLQVGELHGN 496
Query: 422 IAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGR 481
++Q+QR L+ F++ +LVAT+VAARGLDI V VI + P ++ Y+HR GRT R
Sbjct: 497 LSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTAR 556
Query: 482 AGRTGICICFYQPRERGQLRYVEQKAGITFKRVGVPSTMDLVKSKSMDAIRSLASVSYAA 541
AGR G + ER L+ + + A K +P + L K D I + YA
Sbjct: 557 AGRAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVIL---KFRDKIEKMEKDVYAV 613
Query: 542 V 542
+
Sbjct: 614 L 614
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 179 bits (453), Expect = 1e-44
Identities = 119/372 (31%), Positives = 198/372 (53%), Gaps = 23/372 (6%)
Query: 139 FSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIER 198
F + + E ++ + G IQ + P +G D+IAQA++GTGKT +FAI ++++
Sbjct: 35 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
Query: 199 LQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSVACF--YGGTSYQSQINHI 256
L+ + + + LVLAPTRELA Q+ K + + C GGT+ ++++ +
Sbjct: 95 LEI------EFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKL 148
Query: 257 R-NGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTD 315
+ I+VGTPGR+ D L L ++ VLDE D+ML GF +Q+ +I +
Sbjct: 149 QAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKL---- 204
Query: 316 SEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLA-IQCHWSQR 374
+ Q +L SAT P V +V KK+M+ D + + +K T+E + + +
Sbjct: 205 -NTSIQVVLLSATMPTDVLEVTKKFMR------DPIRILVKKEELTLEGIKQFYINVERE 257
Query: 375 PAVIGDVLQVYSG-SEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQSQREITLK 432
+ + +Y + +A+IF T++ V + H + LHGD+ Q +R++ ++
Sbjct: 258 EWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMR 317
Query: 433 GFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFY 492
FR GS +VL+ T++ ARG+D+ +V LVI P + E+YIHR GR GR GR G+ I F
Sbjct: 318 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFV 377
Query: 493 QPRERGQLRYVE 504
++ LR +E
Sbjct: 378 TEEDKRILRDIE 389
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 178 bits (452), Expect = 1e-44
Identities = 123/374 (32%), Positives = 201/374 (53%), Gaps = 26/374 (6%)
Query: 139 FSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIER 198
F + E+ ++ + G IQ + + +G+D+IAQ+++GTGKT +F+I +++
Sbjct: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99
Query: 199 LQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSVACF--YGGTSYQSQINHI 256
L + R + L+LAPTRELA Q+ K + ++V C GGT+ I +
Sbjct: 100 LDI------QVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKL 153
Query: 257 RNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDS 316
G ++ GTPGR+ D ++ L ++ +VLDE D+ML+ GF EQ+ D+ Y +
Sbjct: 154 DYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYR--YLPPA 211
Query: 317 EDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPA 376
Q +L SAT P + ++ K+M D + + ++ T+E + +R
Sbjct: 212 T---QVVLISATLPHEILEMTNKFM------TDPIRILVKRDELTLEGIKQFFVAVEREE 262
Query: 377 VIGDVL-QVYSG-SEGRAIIFCETKKNV---TEMAMNPHIKQNAQCLHGDIAQSQREITL 431
D L +Y + +A+IFC TK+ V TE + ++ +HGD+ Q +RE +
Sbjct: 263 WKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSS--MHGDMPQKERESIM 320
Query: 432 KGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICF 491
K FR G+ +VL++T+V ARGLD+P+V L+I P + E YIHR GR+GR GR G+ I F
Sbjct: 321 KEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINF 380
Query: 492 YQPRERGQLRYVEQ 505
+ + LR +EQ
Sbjct: 381 VKNDDIRILRDIEQ 394
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 177 bits (450), Expect = 2e-44
Identities = 137/442 (30%), Positives = 222/442 (50%), Gaps = 31/442 (7%)
Query: 73 DTEEGFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKSSDNKLEETLTR 132
D FNR + S +++ E++ + + +S L + K + N++
Sbjct: 15 DPVRSFNRWKKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNYEKINVNEITR---- 70
Query: 133 EQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFA 192
FS+FP+S++T+K L+ + IQ +T G +GKD++ A+TG+GKT +F
Sbjct: 71 ------FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFL 124
Query: 193 IPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRK--LSVACFYGGTSYQ 250
+P++E L R Q T VL+++PTRELA Q + + + + S GG +
Sbjct: 125 VPVLEALYRLQWTSTDGLG--VLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 182
Query: 251 SQINHIRNGIDILVGTPGRIKDHL-QSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIH 309
+ I N I+ILV TPGR+ H+ ++ + L+ +VLDE D++LD+GFA+ + +I
Sbjct: 183 HEAERINN-INILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIE 241
Query: 310 ESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQC 369
K QTLLFSAT + V +A+ +K+ E V + K T+E I C
Sbjct: 242 NLPK-----KRQTLLFSATQTKSVKDLARLSLKNP-EYVWVHEKAKYSTPATLEQNYIVC 295
Query: 370 HWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEM-----AMNPHIKQNAQCLHGDIAQ 424
Q+ +V+ L+ S + ++I+F + K V + + P + A LHG Q
Sbjct: 296 ELQQKISVLYSFLR--SHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILA--LHGRQQQ 351
Query: 425 SQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGR 484
+R F VL AT++AARGLD P V+ V+Q P+D +YIHR+GRT R
Sbjct: 352 MRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKE 411
Query: 485 TGICICFYQPRERGQLRYVEQK 506
G + P E+ ++ + QK
Sbjct: 412 DGEALLILLPSEKAMVQQLLQK 433
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 176 bits (445), Expect = 9e-44
Identities = 120/366 (32%), Positives = 186/366 (50%), Gaps = 24/366 (6%)
Query: 138 AFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIE 197
+F ++ LK +G+ + PIQ++ + G+D+I A TG+GKT F +P+I
Sbjct: 182 SFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIM 241
Query: 198 RLQRNQETI--KKSRSPKVLVLAPTRELANQVAKDFK--------DITRKLSVACFYGGT 247
++ + K P L++ P+RELA Q + D + L A GG
Sbjct: 242 FCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGM 301
Query: 248 SYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDI 307
S + Q+ IR+G+ ++V TPGR+ D LQ + L R++ LDE D+M+D+GF + I
Sbjct: 302 SVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTI 361
Query: 308 IHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYM-KSRYEQVDLVGKMTQKAATTVEHLA 366
SY + QTLLFSAT P+ + AK + K V G + VE++
Sbjct: 362 F--SY---FKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYV- 415
Query: 367 IQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQS 425
+ A + +L+ + +IF E K +V + +K A +HG Q
Sbjct: 416 ------KEEAKMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQE 469
Query: 426 QREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRT 485
+R ++ FREG VLVAT+VA++GLD P + VI P+++E+Y+HR GRTGR+G T
Sbjct: 470 ERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNT 529
Query: 486 GICICF 491
GI F
Sbjct: 530 GIATTF 535
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 169 bits (428), Expect = 8e-42
Identities = 117/370 (31%), Positives = 184/370 (49%), Gaps = 19/370 (5%)
Query: 132 REQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSF 191
+++K G F + +S K + +G PIQ KT + +GKD++A ARTG+GKT F
Sbjct: 91 KKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACF 150
Query: 192 AIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLSVACFYGGTSY 249
+P+ ERL+ T + L+L+PTRELA Q K K++ + L A GG
Sbjct: 151 LLPMFERLK----THSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRM 206
Query: 250 QSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIH 309
+ Q + DI++ TPGR+ L L + +VV DE D++ ++GFAEQ+++II
Sbjct: 207 EDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIA 266
Query: 310 ESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYE-QVDLVGKMTQKAATTVEHLAIQ 368
QT+LFSAT P+ + + A+ + ++D+ K+ ++ T+
Sbjct: 267 RL-----PGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSF----FL 317
Query: 369 CHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNAQCLH--GDIAQSQ 426
+ AV+ +L + + ++F TK + E Q C H + +
Sbjct: 318 VREDTKAAVLLHLLHNVVRPQDQTVVFVATKHHA-EYLTELLTTQRVSCAHIYSALDPTA 376
Query: 427 REITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTG 486
R+I L F G L+ T++AARGLDIP +D VI S P + ++HR GR RAGR+G
Sbjct: 377 RKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSG 436
Query: 487 ICICFYQPRE 496
P E
Sbjct: 437 TAYSLVAPDE 446
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 169 bits (428), Expect = 8e-42
Identities = 117/370 (31%), Positives = 184/370 (49%), Gaps = 19/370 (5%)
Query: 132 REQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSF 191
+++K G F + +S K + +G PIQ KT + +GKD++A ARTG+GKT F
Sbjct: 91 KKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACF 150
Query: 192 AIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLSVACFYGGTSY 249
+P+ ERL+ T + L+L+PTRELA Q K K++ + L A GG
Sbjct: 151 LLPMFERLK----THSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRM 206
Query: 250 QSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIH 309
+ Q + DI++ TPGR+ L L + +VV DE D++ ++GFAEQ+++II
Sbjct: 207 EDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIA 266
Query: 310 ESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYE-QVDLVGKMTQKAATTVEHLAIQ 368
QT+LFSAT P+ + + A+ + ++D+ K+ ++ T+
Sbjct: 267 RL-----PGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSF----FL 317
Query: 369 CHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNAQCLH--GDIAQSQ 426
+ AV+ +L + + ++F TK + E Q C H + +
Sbjct: 318 VREDTKAAVLLHLLHNVVRPQDQTVVFVATKHHA-EYLTELLTTQRVSCAHIYSALDPTA 376
Query: 427 REITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTG 486
R+I L F G L+ T++AARGLDIP +D VI S P + ++HR GR RAGR+G
Sbjct: 377 RKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSG 436
Query: 487 ICICFYQPRE 496
P E
Sbjct: 437 TAYSLVAPDE 446
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 166 bits (421), Expect = 6e-41
Identities = 116/403 (28%), Positives = 204/403 (50%), Gaps = 23/403 (5%)
Query: 123 DNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQAR 182
D +++ + K F ++ + E + + G PIQ ++ G+D++A+A+
Sbjct: 82 DLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAK 141
Query: 183 TGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLS--- 239
GTGK+ ++ IPL+ERL ++ I+ +V+ PTRELA QV++ +++ +
Sbjct: 142 NGTGKSGAYLIPLLERLDLKKDNIQ------AMVIVPTRELALQVSQICIQVSKHMGGAK 195
Query: 240 VACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLG 299
V GGT+ + I + + + +++ TPGRI D ++ G + ++ +VLDE D++L
Sbjct: 196 VMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQD 255
Query: 300 FAEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAA 359
F + +EDII K N Q LL+SAT P V K +++ YE ++L+ ++T K
Sbjct: 256 FVQIMEDIILTLPK-----NRQILLYSATFPLSVQKFMNSHLQKPYE-INLMEELTLKGV 309
Query: 360 TTVEHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMN-PHIKQNAQCL 418
T + + LQ+ ++IIFC + + V +A + + +
Sbjct: 310 TQYYAYVTERQKVHCLNTLFSRLQI-----NQSIIFCNSSQRVELLAKKISQLGYSCFYI 364
Query: 419 HGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGR 478
H + Q R FR G + LV T++ RG+DI V++VI P+ E+Y+HR GR
Sbjct: 365 HAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGR 424
Query: 479 TGRAGRTGICICFYQPRERGQLRYVEQKAGITFKRVGVPSTMD 521
+GR G G+ I +R L+ +E++ G K +PS +D
Sbjct: 425 SGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIK--PIPSNID 465
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 166 bits (420), Expect = 7e-41
Identities = 128/409 (31%), Positives = 207/409 (50%), Gaps = 28/409 (6%)
Query: 122 SDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQA 181
S + + + E++ F + +++ + G T IQ++ +G+D+I A
Sbjct: 9 SPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLA 68
Query: 182 RTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV- 240
TG+GKT +FA+P++ L + + LVL PTRELA Q+++ F+ + + V
Sbjct: 69 ETGSGKTGAFALPILNALLETPQRLF------ALVLTPTRELAFQISEQFEALGSSIGVQ 122
Query: 241 -ACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGR-LDLSKLRHVVLDEVDQMLDL 298
A GG SQ + I++ TPGR+ DHL++ + +L L+++V+DE D++L++
Sbjct: 123 SAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNM 182
Query: 299 GFAEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKA 358
F +V+ I+ K D +T LFSAT + V K+ + +K+ V
Sbjct: 183 DFETEVDKIL----KVIPRDR-KTFLFSATMTKKVQKLQRAALKNP------VKCAVSSK 231
Query: 359 ATTVEHLAIQCHWSQRPAVIGDVLQVYSGSE---GRAIIFCETKKNVTEMAMN-PHIKQN 414
TVE L Q ++ P+ D VY +E +IFC T N A+ ++
Sbjct: 232 YQTVEKL--QQYYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFT 289
Query: 415 AQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIH 474
A LHG ++QS+R +L F+ + +L+AT+VA+RGLDIP VD+V+ P + YIH
Sbjct: 290 AIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIH 349
Query: 475 RSGRTGRAGRTGICICFYQPRERGQLRYVEQKAGITFKRVGVPSTMDLV 523
R GRT RAGR+G I F + + +E G K G P+ D V
Sbjct: 350 RVGRTARAGRSGKAITFVTQYDVELFQRIEHLIG--KKLPGFPTQDDEV 396
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 157 bits (396), Expect = 4e-38
Identities = 101/348 (29%), Positives = 180/348 (51%), Gaps = 25/348 (7%)
Query: 152 LKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQETIKKSRS 211
LK G PIQ++ G+D++A A TG+GKT +F +P+I R + +S++
Sbjct: 218 LKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR------ALFESKT 271
Query: 212 PKVLVLAPTRELANQVAKDFKDITR---KLSVACFYGGTSYQSQINHIRNGIDILVGTPG 268
P L+L PTRELA Q+ + K++ ++ GG Q+ ++ + +++ TPG
Sbjct: 272 PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPG 331
Query: 269 RIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDNPQTLLFSAT 328
R+ D ++ ++L ++ VV+DE D ML +GF +QV DI+ E+ D QT+L SAT
Sbjct: 332 RLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDIL-ENIPNDC----QTILVSAT 386
Query: 329 CPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAVIGDVLQVYSGS 388
P + ++A + + + V ++ V + + W + PA + ++ +
Sbjct: 387 IPTSIEQLASQLL---HNPVRIITGEKNLPCANVRQIIL---WVEDPAKKKKLFEILNDK 440
Query: 389 E---GRAIIF--CETKKNVTEMAMNPHIKQNAQCLHGDIAQSQREITLKGFREGSFKVLV 443
+ ++F C+ ++ A+ + +H + +Q +R+ LKG EG ++V+V
Sbjct: 441 KLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVV 500
Query: 444 ATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICF 491
+T V RGLD+ V LV+ P ++ Y+H+ GR GR G+ G I F
Sbjct: 501 STGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITF 548
>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
sapiens]
Length = 600
Score = 154 bits (389), Expect = 3e-37
Identities = 113/387 (29%), Positives = 199/387 (51%), Gaps = 28/387 (7%)
Query: 136 EGAFSNFPIS--EETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAI 193
EG++ + P+ + + L+ G Y+ P+Q T KD+ A+A TG+GKT +F I
Sbjct: 6 EGSWESLPVPLHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVI 65
Query: 194 PLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR---KLSVACFYGGTSYQ 250
P++E L R +E +KKS+ +++ PTRELA Q+ + T+ + S + GG +
Sbjct: 66 PILEILLRREEKLKKSQVGAIII-TPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPG 124
Query: 251 SQINHIRN-GIDILVGTPGRIKDHLQ--SGRLDLSK----LRHVVLDEVDQMLDLGFAEQ 303
+ + G +I+V TPGR++D + + LDL+ L +VLDE D++LD+GF
Sbjct: 125 EDVERFKQQGGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEAS 184
Query: 304 VEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKS----RYEQVDLVGKMTQKAA 359
+ I+ K +T LFSAT Q V + + +++ ++ + QK
Sbjct: 185 INTILEFLPK-----QRRTGLFSATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTP 239
Query: 360 TTVEHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEM--AMNPHIKQ-NAQ 416
+ +E+ + C ++ + L+ + + + ++F T V A+ +K
Sbjct: 240 SRLENYYMVCKADEKFNQLVHFLRNHK--QEKHLVFFSTCACVEYYGKALEVLVKGVKIM 297
Query: 417 CLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRS 476
C+HG + + +I ++ FR+ +LV T+V ARG+DIPEV+ V+Q PP + +++HR
Sbjct: 298 CIHGKMKYKRNKIFME-FRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRC 356
Query: 477 GRTGRAGRTGICICFYQPRERGQLRYV 503
GRT R G G + F P E + ++
Sbjct: 357 GRTARIGHGGSALVFLLPMEESYINFL 383
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,192,187
Number of Sequences: 37866
Number of extensions: 1249176
Number of successful extensions: 9942
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 215
Number of HSP's successfully gapped in prelim test: 335
Number of HSP's that attempted gapping in prelim test: 6292
Number of HSP's gapped (non-prelim): 2968
length of query: 737
length of database: 18,247,518
effective HSP length: 110
effective length of query: 627
effective length of database: 14,082,258
effective search space: 8829575766
effective search space used: 8829575766
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.