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Search of human proteins with 109134349
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109134349 coatomer protein complex, subunit gamma 2 [Homo
sapiens]
(871 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109134349 coatomer protein complex, subunit gamma 2 [Homo sap... 1713 0.0
gi|11559929 coatomer protein complex, subunit gamma 1 [Homo sapi... 1422 0.0
gi|166197671 adaptor-related protein complex 4, beta 1 subunit [... 68 3e-11
gi|22027651 adaptor-related protein complex 1 beta 1 subunit iso... 67 9e-11
gi|22027653 adaptor-related protein complex 1 beta 1 subunit iso... 67 9e-11
gi|71773106 adaptor-related protein complex 2, beta 1 subunit is... 65 2e-10
gi|4557469 adaptor-related protein complex 2, beta 1 subunit iso... 65 2e-10
gi|71773010 adaptor-related protein complex 1, gamma 1 subunit i... 61 4e-09
gi|71772942 adaptor-related protein complex 1, gamma 1 subunit i... 57 1e-07
gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit... 47 8e-05
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H... 47 1e-04
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 39 0.021
gi|221316632 coatomer protein complex, subunit beta 1 [Homo sapi... 37 0.061
gi|221316630 coatomer protein complex, subunit beta 1 [Homo sapi... 37 0.061
gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens] 37 0.061
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 37 0.080
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] 36 0.18
gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens] 36 0.18
gi|169160755 PREDICTED: zyg-11 homolog A (C. elegans) [Homo sapi... 33 1.5
gi|88948888 PREDICTED: zyg-11 homolog A (C. elegans) [Homo sapiens] 33 1.5
gi|113408672 PREDICTED: zyg-11 homolog A [Homo sapiens] 33 1.5
gi|226437632 zyg-11 homolog A [Homo sapiens] 33 1.5
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 32 3.3
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 31 5.7
gi|142976733 surface glycoprotein, Ig superfamily member [Homo s... 31 5.7
gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens] 30 7.4
gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens] 30 7.4
gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens] 30 7.4
gi|110630018 eukaryotic translation initiation factor 4 gamma, 2... 30 7.4
gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i... 30 7.4
>gi|109134349 coatomer protein complex, subunit gamma 2 [Homo
sapiens]
Length = 871
Score = 1713 bits (4437), Expect = 0.0
Identities = 871/871 (100%), Positives = 871/871 (100%)
Query: 1 MIKKFDKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEH 60
MIKKFDKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEH
Sbjct: 1 MIKKFDKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEH 60
Query: 61 FGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVY 120
FGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVY
Sbjct: 61 FGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVY 120
Query: 121 RGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINE 180
RGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINE
Sbjct: 121 RGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINE 180
Query: 181 AQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLL 240
AQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLL
Sbjct: 181 AQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLL 240
Query: 241 KETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPK 300
KETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPK
Sbjct: 241 KETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPK 300
Query: 301 PALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRL 360
PALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRL
Sbjct: 301 PALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRL 360
Query: 361 MKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRDDGGFEYKRAIVDC 420
MKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRDDGGFEYKRAIVDC
Sbjct: 361 MKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRDDGGFEYKRAIVDC 420
Query: 421 IISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRV 480
IISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRV
Sbjct: 421 IISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRV 480
Query: 481 VLENEAVRAAAVSALAKFGAQNESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQM 540
VLENEAVRAAAVSALAKFGAQNESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQM
Sbjct: 481 VLENEAVRAAAVSALAKFGAQNESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQM 540
Query: 541 ALNATYIFNGLTVSVPGMEKALHQYTLEPSEKPFDMKSIPLAMAPVFEQKAEITLVATKP 600
ALNATYIFNGLTVSVPGMEKALHQYTLEPSEKPFDMKSIPLAMAPVFEQKAEITLVATKP
Sbjct: 541 ALNATYIFNGLTVSVPGMEKALHQYTLEPSEKPFDMKSIPLAMAPVFEQKAEITLVATKP 600
Query: 601 EKLAPSRQDIFQEQLAAIPEFLNIGPLFKSSEPVQLTEAETEYFVRCIKHMFTNHIVFQF 660
EKLAPSRQDIFQEQLAAIPEFLNIGPLFKSSEPVQLTEAETEYFVRCIKHMFTNHIVFQF
Sbjct: 601 EKLAPSRQDIFQEQLAAIPEFLNIGPLFKSSEPVQLTEAETEYFVRCIKHMFTNHIVFQF 660
Query: 661 DCTNTLNDQLLEKVTVQMEPSDSYEVLSCIPAPSLPYNQPGICYTLVRLPDDDPTAVAGS 720
DCTNTLNDQLLEKVTVQMEPSDSYEVLSCIPAPSLPYNQPGICYTLVRLPDDDPTAVAGS
Sbjct: 661 DCTNTLNDQLLEKVTVQMEPSDSYEVLSCIPAPSLPYNQPGICYTLVRLPDDDPTAVAGS 720
Query: 721 FSCTMKFTVRDCDPNTGVPDEDGYDDEYVLEDLEVTVSDHIQKVLKPNFAAAWEEVGDTF 780
FSCTMKFTVRDCDPNTGVPDEDGYDDEYVLEDLEVTVSDHIQKVLKPNFAAAWEEVGDTF
Sbjct: 721 FSCTMKFTVRDCDPNTGVPDEDGYDDEYVLEDLEVTVSDHIQKVLKPNFAAAWEEVGDTF 780
Query: 781 EKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAGIFRGGYDLLVR 840
EKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAGIFRGGYDLLVR
Sbjct: 781 EKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAGIFRGGYDLLVR 840
Query: 841 SRLALADGVTMQVTVRSKERTPVDVILASVG 871
SRLALADGVTMQVTVRSKERTPVDVILASVG
Sbjct: 841 SRLALADGVTMQVTVRSKERTPVDVILASVG 871
>gi|11559929 coatomer protein complex, subunit gamma 1 [Homo
sapiens]
Length = 874
Score = 1422 bits (3680), Expect = 0.0
Identities = 704/874 (80%), Positives = 793/874 (90%), Gaps = 3/874 (0%)
Query: 1 MIKKFDKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEH 60
M+KKFDKKDEESG GSNPFQHLEKSAVLQEAR+FNETPINPR+C HILTKILYL+NQGEH
Sbjct: 1 MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEH 60
Query: 61 FGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVY 120
GTTEATEAFFAMT+LFQSND TLRRMCYLTIKEM+ I+EDVIIVTSSLTKDMTGKED Y
Sbjct: 61 LGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNY 120
Query: 121 RGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINE 180
RGPA+RALC+ITD TMLQAIERYMKQAIVDKV SVSSSALVSSLH++K S+DVVKRW+NE
Sbjct: 121 RGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNE 180
Query: 181 AQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLL 240
AQEAASSDNIMVQYHALG+LYH+RKNDRLAV+KM++K T+ GLKS FAYCM+IR+AS+ L
Sbjct: 181 AQEAASSDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHGLKSPFAYCMMIRVASKQL 240
Query: 241 KETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPK 300
+E + +SPLFDFIESCLRNKHEMV+YEAASAI++LP C+A+ELAPAVSVLQLFCSSPK
Sbjct: 241 EEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPK 300
Query: 301 PALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRL 360
ALRYAAVRTLNKVAMKHPSAVTACNLDLENL+TDSNRSIATLAITTLLKTGSESS+DRL
Sbjct: 301 AALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRL 360
Query: 361 MKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRDDGGFEYKRAIVDC 420
MKQISSF+SEISDEFKVVVVQAISALCQKYPRKH+V+M FL MLR++GGFEYKRAIVDC
Sbjct: 361 MKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDC 420
Query: 421 IISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRV 480
IISI+EEN ESKE GL+HLCEFIEDCE TVLAT+ILHLLG+EGP+T PSKYIRFI+NRV
Sbjct: 421 IISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTTNPSKYIRFIYNRV 480
Query: 481 VLENEAVRAAAVSALAKFGAQNESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQM 540
VLE+E VRA AVSALAKFGAQNE +LPSILVLL+RC+MD D+EVRDRATFYLNVL+Q+Q
Sbjct: 481 VLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQK 540
Query: 541 ALNATYIFNGLTVSVPGMEKALHQYTLEPSEKPFDMKSIPLAMAPVFEQKAEITLVAT-- 598
ALNA YI NGLTVS+PG+E+AL QYTLEPSEKPFD+KS+PLA AP+ EQ+ E T +
Sbjct: 541 ALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLKSVPLATAPMAEQRTESTPITAVK 600
Query: 599 KPEKLAPSRQDIFQEQLAAIPEFLNIGPLFKSS-EPVQLTEAETEYFVRCIKHMFTNHIV 657
+PEK+A +RQ+IFQEQLAA+PEF +GPLFKSS EPV LTE+ETEY +RC KH FTNH+V
Sbjct: 601 QPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPVALTESETEYVIRCTKHTFTNHMV 660
Query: 658 FQFDCTNTLNDQLLEKVTVQMEPSDSYEVLSCIPAPSLPYNQPGICYTLVRLPDDDPTAV 717
FQFDCTNTLNDQ LE VTVQMEP+++YEVL +PA SLPYNQPG CYTLV LP +DPTAV
Sbjct: 661 FQFDCTNTLNDQTLENVTVQMEPTEAYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAV 720
Query: 718 AGSFSCTMKFTVRDCDPNTGVPDEDGYDDEYVLEDLEVTVSDHIQKVLKPNFAAAWEEVG 777
A +FSC MKFTV+DCDP TG D++GY+DEYVLEDLEVTV+DHIQKV+K NF AAW+EVG
Sbjct: 721 ACTFSCMMKFTVKDCDPTTGETDDEGYEDEYVLEDLEVTVADHIQKVMKLNFEAAWDEVG 780
Query: 778 DTFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAGIFRGGYDL 837
D FEKEETF LS+ KTLEEAV NI+ FLGM PCERSDKVP+NKN+H+L LAG+FRGG+D+
Sbjct: 781 DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAGVFRGGHDI 840
Query: 838 LVRSRLALADGVTMQVTVRSKERTPVDVILASVG 871
LVRSRL L D VTMQVT RS E PVD+ILASVG
Sbjct: 841 LVRSRLLLLDTVTMQVTARSLEELPVDIILASVG 874
>gi|166197671 adaptor-related protein complex 4, beta 1 subunit
[Homo sapiens]
Length = 739
Score = 68.2 bits (165), Expect = 3e-11
Identities = 99/514 (19%), Positives = 217/514 (42%), Gaps = 40/514 (7%)
Query: 43 RCLHILTKILYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDV 102
R +++ +++ + QG + + F M + + D +++ YL + A + D+
Sbjct: 28 RYRNVIQRVIRYMTQG-----LDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDL 82
Query: 103 -IIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALV 161
++ ++L KD + + RG A+R++C + + + I++ + + DK S V A++
Sbjct: 83 ALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPILNGLRDKASYVRRVAVL 142
Query: 162 --SSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKND-RLAVSK----- 213
+ +H + +V +NE + +V + L L + K + + ++K
Sbjct: 143 GCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQEGGVVINKPIAHH 202
Query: 214 MLNKFTKSGLKSQFAYC-MLIRIASRLLKETEDGHESPLFDFIESCLRNKHEMVIYEAAS 272
+LN+ +K Q L+R R +E D + + ++S L++ V+ A
Sbjct: 203 LLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFD-----ILNLLDSFLKSSSPGVVMGATK 257
Query: 273 AIIHL----PNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLD 328
+ L P+ L L CSS L + A+ + ++ P ++
Sbjct: 258 LFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKK 317
Query: 329 LENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQ 388
++ + I + L + ++ +V ++++++ + +++S +F + AI + +
Sbjct: 318 FFCSYSEPH-YIKLQKVEVLCELVNDENVQQVLEELRGYCTDVSADFAQAAIFAIGGIAR 376
Query: 389 KYPRKHSVMMTFLSNMLRDDGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEH 448
Y + ++T L + ++ +V +V P+ EA +C+ + CE
Sbjct: 377 TYTDQCVQILTELLGLRQE----HITTVVVQTFRDLVWLCPQCTEA----VCQALPGCEE 428
Query: 449 TVLATK----ILHLLGKEGPRTP-VPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQNE 503
+ ++ ++ LLG G R P P F+ N AV+ ++AL +
Sbjct: 429 NIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTALLRLFLSRP 488
Query: 504 SLLPSIL-VLLQRCMMDTDD-EVRDRATFYLNVL 535
+ +L LL C+ + D VRDR FY +L
Sbjct: 489 AECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLL 522
>gi|22027651 adaptor-related protein complex 1 beta 1 subunit
isoform a [Homo sapiens]
Length = 949
Score = 66.6 bits (161), Expect = 9e-11
Identities = 86/500 (17%), Positives = 213/500 (42%), Gaps = 32/500 (6%)
Query: 65 EATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDV-IIVTSSLTKDMTGKEDVYRGP 123
+ + F + Q+++ L+++ YL + A D+ I+ ++ KD + R
Sbjct: 46 DVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRAL 105
Query: 124 AIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKR--WINEA 181
A+R + I + + + +++ + D+ V +A V + I+ +V+ +++
Sbjct: 106 AVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTL 165
Query: 182 QEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYC-------MLIR 234
++ S N MV +A+ L + ++ + LN + + L + C +L
Sbjct: 166 KDLISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDC 225
Query: 235 IASRLLKETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQL 294
+A+ + K+ D + + + L + + V+ A ++ +++L ++L+
Sbjct: 226 LANYMPKD--DREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKK 283
Query: 295 FCS------SPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATL--AIT 346
S +P L+Y A+R +N + K P + +++ N I +
Sbjct: 284 LAPPLVTLLSAEPELQYVALRNINLIVQKRPEIL---KHEMKVFFVKYNDPIYVKLEKLD 340
Query: 347 TLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLR 406
+++ S++++ +++ ++ + +E+ +F V+AI K + ++ L ++++
Sbjct: 341 IMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQ 400
Query: 407 DDGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRT 466
+ + AIV I I + P E+ +A LCE ++ + ++ ++G+ R
Sbjct: 401 TKVNYVVQEAIV-VIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERI 459
Query: 467 PVPSKYIRFIFNRVVLENEAVRAAAVSALAKF----GAQNESLLPSILVLLQRCMMDTDD 522
+ + E+ V+ ++A+ K + + L+ +L L D+D+
Sbjct: 460 DNADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSL---ATQDSDN 516
Query: 523 -EVRDRATFYLNVLQQRQMA 541
++RDR Y +L +A
Sbjct: 517 PDLRDRGYIYWRLLSTDPVA 536
>gi|22027653 adaptor-related protein complex 1 beta 1 subunit
isoform b [Homo sapiens]
Length = 942
Score = 66.6 bits (161), Expect = 9e-11
Identities = 86/500 (17%), Positives = 213/500 (42%), Gaps = 32/500 (6%)
Query: 65 EATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDV-IIVTSSLTKDMTGKEDVYRGP 123
+ + F + Q+++ L+++ YL + A D+ I+ ++ KD + R
Sbjct: 46 DVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRAL 105
Query: 124 AIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKR--WINEA 181
A+R + I + + + +++ + D+ V +A V + I+ +V+ +++
Sbjct: 106 AVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTL 165
Query: 182 QEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYC-------MLIR 234
++ S N MV +A+ L + ++ + LN + + L + C +L
Sbjct: 166 KDLISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDC 225
Query: 235 IASRLLKETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQL 294
+A+ + K+ D + + + L + + V+ A ++ +++L ++L+
Sbjct: 226 LANYMPKD--DREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKK 283
Query: 295 FCS------SPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATL--AIT 346
S +P L+Y A+R +N + K P + +++ N I +
Sbjct: 284 LAPPLVTLLSAEPELQYVALRNINLIVQKRPEIL---KHEMKVFFVKYNDPIYVKLEKLD 340
Query: 347 TLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLR 406
+++ S++++ +++ ++ + +E+ +F V+AI K + ++ L ++++
Sbjct: 341 IMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQ 400
Query: 407 DDGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRT 466
+ + AIV I I + P E+ +A LCE ++ + ++ ++G+ R
Sbjct: 401 TKVNYVVQEAIV-VIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERI 459
Query: 467 PVPSKYIRFIFNRVVLENEAVRAAAVSALAKF----GAQNESLLPSILVLLQRCMMDTDD 522
+ + E+ V+ ++A+ K + + L+ +L L D+D+
Sbjct: 460 DNADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSL---ATQDSDN 516
Query: 523 -EVRDRATFYLNVLQQRQMA 541
++RDR Y +L +A
Sbjct: 517 PDLRDRGYIYWRLLSTDPVA 536
>gi|71773106 adaptor-related protein complex 2, beta 1 subunit
isoform a [Homo sapiens]
Length = 951
Score = 65.5 bits (158), Expect = 2e-10
Identities = 86/493 (17%), Positives = 206/493 (41%), Gaps = 30/493 (6%)
Query: 65 EATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDV-IIVTSSLTKDMTGKEDVYRGP 123
+ + F + Q+++ L+++ YL + A D+ I+ +S KD + R
Sbjct: 46 DVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRAL 105
Query: 124 AIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKR--WINEA 181
A+R + I + + + +++ + D+ V +A V + I+ +V+ +++
Sbjct: 106 AVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSL 165
Query: 182 QEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYC-----MLIRIA 236
++ + N MV +A+ L + ++ + LN + L + C + I
Sbjct: 166 RDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDC 225
Query: 237 SRLLKETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIH----LP------NCTARELA 286
+D + + + L + + V+ A ++ LP N ++LA
Sbjct: 226 LSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLA 285
Query: 287 PAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATL--A 344
P + L S +P ++Y A+R +N + K P + +++ N I
Sbjct: 286 PPLVTLL----SGEPEVQYVALRNINLIVQKRPEIL---KQEIKVFFVKYNDPIYVKLEK 338
Query: 345 ITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNM 404
+ +++ S++++ +++ ++ + +E+ +F V+AI K + ++ L ++
Sbjct: 339 LDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDL 398
Query: 405 LRDDGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGP 464
++ + + AIV I I + P E+ +A LCE ++ + ++ ++G+
Sbjct: 399 IQTKVNYVVQEAIV-VIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAE 457
Query: 465 RTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQNESLLPSIL-VLLQRCMMDTDD- 522
R + + E+ V+ ++A+ K + S ++ +L D+D+
Sbjct: 458 RIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNP 517
Query: 523 EVRDRATFYLNVL 535
++RDR Y +L
Sbjct: 518 DLRDRGYIYWRLL 530
>gi|4557469 adaptor-related protein complex 2, beta 1 subunit
isoform b [Homo sapiens]
Length = 937
Score = 65.5 bits (158), Expect = 2e-10
Identities = 86/493 (17%), Positives = 206/493 (41%), Gaps = 30/493 (6%)
Query: 65 EATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDV-IIVTSSLTKDMTGKEDVYRGP 123
+ + F + Q+++ L+++ YL + A D+ I+ +S KD + R
Sbjct: 46 DVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRAL 105
Query: 124 AIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKR--WINEA 181
A+R + I + + + +++ + D+ V +A V + I+ +V+ +++
Sbjct: 106 AVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSL 165
Query: 182 QEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYC-----MLIRIA 236
++ + N MV +A+ L + ++ + LN + L + C + I
Sbjct: 166 RDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDC 225
Query: 237 SRLLKETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIH----LP------NCTARELA 286
+D + + + L + + V+ A ++ LP N ++LA
Sbjct: 226 LSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLA 285
Query: 287 PAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATL--A 344
P + L S +P ++Y A+R +N + K P + +++ N I
Sbjct: 286 PPLVTLL----SGEPEVQYVALRNINLIVQKRPEIL---KQEIKVFFVKYNDPIYVKLEK 338
Query: 345 ITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNM 404
+ +++ S++++ +++ ++ + +E+ +F V+AI K + ++ L ++
Sbjct: 339 LDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDL 398
Query: 405 LRDDGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGP 464
++ + + AIV I I + P E+ +A LCE ++ + ++ ++G+
Sbjct: 399 IQTKVNYVVQEAIV-VIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAE 457
Query: 465 RTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQNESLLPSIL-VLLQRCMMDTDD- 522
R + + E+ V+ ++A+ K + S ++ +L D+D+
Sbjct: 458 RIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNP 517
Query: 523 EVRDRATFYLNVL 535
++RDR Y +L
Sbjct: 518 DLRDRGYIYWRLL 530
>gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
isoform a [Homo sapiens]
Length = 825
Score = 61.2 bits (147), Expect = 4e-09
Identities = 81/407 (19%), Positives = 164/407 (40%), Gaps = 48/407 (11%)
Query: 40 NPRRCLHILTKILYL--LNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMAT 97
N RC ++ K+LY+ L HFG E +L S T +R+ YL +
Sbjct: 43 NTYRCRNV-AKLLYMHMLGYPAHFGQLECL-------KLIASQKFTDKRIGYLGAMLLLD 94
Query: 98 ISEDV-IIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVS 156
+DV +++T+ + D+ +G A+ L + M + + +++ + S +
Sbjct: 95 ERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLR 154
Query: 157 SSALVSSLH-------MMKISYDVVKRWINEAQEAASSDNIMVQYHAL----GVLYHLRK 205
A + ++H +M++ K +NE ++++ +L H RK
Sbjct: 155 KKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK 214
Query: 206 NDRLA-----------VSKMLNKFTKSGLKSQFAYCMLIRIASRLLKETEDGHESPLFDF 254
N++L +S + SG+ F ++R+ R+L +D + D
Sbjct: 215 NEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDI 273
Query: 255 IESCLRNKH------EMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPKPALRYAAV 308
+ N ++YE I+ + + + + A+++L F + +RY A+
Sbjct: 274 LAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVL-AINILGRFLLNNDKNIRYVAL 332
Query: 309 RTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFV 368
+L K +AV + + + D + SI A+ + +++ +MK++ F+
Sbjct: 333 TSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFL 392
Query: 369 SEISDEFKVVVVQAISALCQKY-PRKH----SVM--MTFLSNMLRDD 408
EFK I +KY P K ++M +T + +RDD
Sbjct: 393 DSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDD 439
>gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
isoform b [Homo sapiens]
Length = 822
Score = 56.6 bits (135), Expect = 1e-07
Identities = 80/404 (19%), Positives = 161/404 (39%), Gaps = 45/404 (11%)
Query: 40 NPRRCLHILTKILYL--LNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMAT 97
N RC ++ K+LY+ L HFG E +L S T +R+ YL +
Sbjct: 43 NTYRCRNV-AKLLYMHMLGYPAHFGQLECL-------KLIASQKFTDKRIGYLGAMLLLD 94
Query: 98 ISEDV-IIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVS 156
+DV +++T+ + D+ +G A+ L + M + + +++ + S +
Sbjct: 95 ERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLR 154
Query: 157 SSALVSSLH-------MMKISYDVVKRWINEAQEAASSDNIMVQYHAL----GVLYHLRK 205
A + ++H +M++ K +NE ++++ +L H RK
Sbjct: 155 KKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK 214
Query: 206 N--------DRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLLKETEDGHESPLFDFIES 257
L +S + SG+ F ++R+ R+L +D + D +
Sbjct: 215 LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDILAQ 273
Query: 258 CLRNKH------EMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPKPALRYAAVRTL 311
N ++YE I+ + + + + A+++L F + +RY A+ +L
Sbjct: 274 VATNTETSKNVGNAILYETVLTIMDIKSESGLRVL-AINILGRFLLNNDKNIRYVALTSL 332
Query: 312 NKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEI 371
K +AV + + + D + SI A+ + +++ +MK++ F+
Sbjct: 333 LKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSC 392
Query: 372 SDEFKVVVVQAISALCQKY-PRKH----SVM--MTFLSNMLRDD 408
EFK I +KY P K ++M +T + +RDD
Sbjct: 393 EPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDD 436
>gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit
[Homo sapiens]
Length = 1137
Score = 47.0 bits (110), Expect = 8e-05
Identities = 92/542 (16%), Positives = 215/542 (39%), Gaps = 48/542 (8%)
Query: 20 QHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEHFGTTEATEAFFAMTRLFQS 79
+H E+ + QE T P L ++ + + L E G +A+ + +L Q
Sbjct: 49 KHEEEKLIQQELSSLKATVSAPTTTLKMMKECMVRLIYCEMLGY-DASFGYIHAIKLAQQ 107
Query: 80 NDQTLRRMCYLTIKEMATISEDVIIV-TSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQ 138
+ +R+ YL + S +++++ +++ KD+ V A+ + +I M+
Sbjct: 108 GNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVVSQIFPCEMIP 167
Query: 139 AIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALG 198
A+ ++ + V A+++ I+ + V+ + ++A ++ V +L
Sbjct: 168 AVLPLIEDKLQHSKEIVRRKAVLALYKFHLIAPNQVQHIHIKFRKALCDRDVGVMAASLH 227
Query: 199 VLYHLRKND----------------RLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLLKE 242
+ + K + ++ K+ +F + + + L+RI L K+
Sbjct: 228 IYLRMIKENSSGYKDLTGSFVTILKQVVGGKLPVEFNYHSVPAPWLQIQLLRILGLLGKD 287
Query: 243 TEDGHESPLFDFIESCLR------NKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFC 296
+ E ++D ++ LR N +++E + + + L A + F
Sbjct: 288 DQRTSEL-MYDVLDESLRRAELNHNVTYAILFECVHTVYSIYP-KSELLEKAAKCIGKFV 345
Query: 297 SSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESS 356
SPK L+Y ++ L V + P+ + + + + I + L + + +
Sbjct: 346 LSPKINLKYLGLKALTYVIQQDPTLALQHQMTIIECLDHPDPIIKRETLELLYRITNAQN 405
Query: 357 VDRLMKQISSFVSEISDEFKVV-VVQAISALCQKYPRKHSVMMTFLSNMLRDDGGFEYKR 415
+ +++++ ++ + +E+ +V +V I+ L +KY ++ + + N + GG
Sbjct: 406 ITVIVQKMLEYLHQSKEEYVIVNLVGKIAELAEKYAPDNAWFIQTM-NAVFSVGGDVMHP 464
Query: 416 AIVDCIISIV----EENPESKEAGLAHLCEFIE--DCEHTVLATKIL-----------HL 458
I + + ++ ++ E ++ L + ++ D E+ + L +L
Sbjct: 465 DIPNNFLRLLAEGFDDETEDQQLRLYAVQSYLTLLDMENVFYPQRFLQVMSWVLGEYSYL 524
Query: 459 LGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQN---ESLLPSILVLLQR 515
L KE P + Y + + V E +A AAV+ L + E L+ + L
Sbjct: 525 LDKETPEEVIAKLYKLLMNDSVSSETKAWLIAAVTKLTSQAHSSNTVERLIHEFTISLDT 584
Query: 516 CM 517
CM
Sbjct: 585 CM 586
>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
sapiens]
Length = 785
Score = 46.6 bits (109), Expect = 1e-04
Identities = 62/371 (16%), Positives = 154/371 (41%), Gaps = 37/371 (9%)
Query: 48 LTKILY--LLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDV-II 104
L K+LY +L HFG E +L S+ T +R+ YL + D ++
Sbjct: 51 LAKLLYVHMLGYPAHFGQMECL-------KLIASSRFTDKRVGYLGAMLLLDERHDAHLL 103
Query: 105 VTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSL 164
+T+S+ D++ +G A+ L + M + + +++ ++ V A+++++
Sbjct: 104 ITNSIKNDLSQGIQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQPSPYVRKKAILTAV 163
Query: 165 HMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKND-------RLAVSKMLN- 216
HM++ ++ ++ + + + + ++ L + R V ++++
Sbjct: 164 HMIRKVPELSSVFLPPCAQLLHERHHGILLGTITLITELCERSPAALRHFRKVVPQLVHI 223
Query: 217 -----------KFTKSGLKSQFAYCMLIRIASRLLKETEDGHESPLFDFIESCL------ 259
+ + SG+ F ++R+ L + E+ E+ + D +
Sbjct: 224 LRTLVTMGYSTEHSISGVSDPFLQVQILRLLRILGRNHEESSET-MNDLLAQVATNTDTS 282
Query: 260 RNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHP 319
RN V++E I+ + + + AV++L F + +RY A+ +L ++
Sbjct: 283 RNAGNAVLFETVLTIMDIRSAAGLRVL-AVNILGRFLLNSDRNIRYVALTSLLRLVQSDH 341
Query: 320 SAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVV 379
SAV + + +++ S++ A+ L + S+V +M+++ +F+ + +
Sbjct: 342 SAVQRHRPTVVECLRETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADC 401
Query: 380 VQAISALCQKY 390
I +++
Sbjct: 402 ASGILLAAERF 412
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 38.9 bits (89), Expect = 0.021
Identities = 36/195 (18%), Positives = 79/195 (40%), Gaps = 7/195 (3%)
Query: 340 IATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMT 399
I TL + L +E+++ L+++ ++V +F +Q I +
Sbjct: 385 IKTLKLEILTNLANEANISTLLREFQTYVKSQDKQFAAATIQTIGRCATNILEVTDTCLN 444
Query: 400 FLSNMLRDDGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLL 459
L +L + ++V I +++ P + H+ + ++ V IL L+
Sbjct: 445 GLVCLLSNRDEIVVAESVV-VIKKLLQMQPAQHGEIIKHMAKLLDSITVPVARASILWLI 503
Query: 460 GKEGPRTP-VPSKYIRFIFNRVVLENEAVRAAAVSALAKF---GAQNESLLPSILVLLQR 515
G+ R P + +R + E++ V+ ++ AK ++ LL ++ L +
Sbjct: 504 GENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLGAKLYLTNSKQTKLLTQYILNLGK 563
Query: 516 CMMDTDDEVRDRATF 530
D + ++RDR F
Sbjct: 564 --YDQNYDIRDRTRF 576
>gi|221316632 coatomer protein complex, subunit beta 1 [Homo
sapiens]
Length = 953
Score = 37.4 bits (85), Expect = 0.061
Identities = 52/274 (18%), Positives = 117/274 (42%), Gaps = 59/274 (21%)
Query: 101 DVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSAL 160
++I+V + KD+ + RG +R LC++ + +L+ + ++ + + S V +A+
Sbjct: 97 EMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAV 156
Query: 161 VSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTK 220
++ + Y + I +A E +++ N++ A K
Sbjct: 157 LA----IYTIYRNFEHLIPDAPE---------------LIHDFLVNEKDASCK------- 190
Query: 221 SGLKSQFAYCMLIRIASRLLKETEDGHESPLFDFIESCLRNKH------EMVIYEAASAI 274
+ A+ MLI + D++ +C+ ++VI E +
Sbjct: 191 -----RNAFMMLIH-----------ADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKV 234
Query: 275 IHL-PNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTA---CNLDLE 330
H P+ AR + ++LQ S PA++Y A TL ++ P+A+ A C +DL
Sbjct: 235 CHANPSERARFIRCIYNLLQ----SSSPAVKYEAAGTLVTLS-SAPTAIKAAAQCYIDL- 288
Query: 331 NLITDSNRSIATLAITTLLKTGSESSVDRLMKQI 364
+I +S+ ++ + + L++ + +R+++ +
Sbjct: 289 -IIKESDNNVKLIVLDRLIELKEHPAHERVLQDL 321
>gi|221316630 coatomer protein complex, subunit beta 1 [Homo
sapiens]
Length = 953
Score = 37.4 bits (85), Expect = 0.061
Identities = 52/274 (18%), Positives = 117/274 (42%), Gaps = 59/274 (21%)
Query: 101 DVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSAL 160
++I+V + KD+ + RG +R LC++ + +L+ + ++ + + S V +A+
Sbjct: 97 EMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAV 156
Query: 161 VSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTK 220
++ + Y + I +A E +++ N++ A K
Sbjct: 157 LA----IYTIYRNFEHLIPDAPE---------------LIHDFLVNEKDASCK------- 190
Query: 221 SGLKSQFAYCMLIRIASRLLKETEDGHESPLFDFIESCLRNKH------EMVIYEAASAI 274
+ A+ MLI + D++ +C+ ++VI E +
Sbjct: 191 -----RNAFMMLIH-----------ADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKV 234
Query: 275 IHL-PNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTA---CNLDLE 330
H P+ AR + ++LQ S PA++Y A TL ++ P+A+ A C +DL
Sbjct: 235 CHANPSERARFIRCIYNLLQ----SSSPAVKYEAAGTLVTLS-SAPTAIKAAAQCYIDL- 288
Query: 331 NLITDSNRSIATLAITTLLKTGSESSVDRLMKQI 364
+I +S+ ++ + + L++ + +R+++ +
Sbjct: 289 -IIKESDNNVKLIVLDRLIELKEHPAHERVLQDL 321
>gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens]
Length = 953
Score = 37.4 bits (85), Expect = 0.061
Identities = 52/274 (18%), Positives = 117/274 (42%), Gaps = 59/274 (21%)
Query: 101 DVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSAL 160
++I+V + KD+ + RG +R LC++ + +L+ + ++ + + S V +A+
Sbjct: 97 EMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAV 156
Query: 161 VSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTK 220
++ + Y + I +A E +++ N++ A K
Sbjct: 157 LA----IYTIYRNFEHLIPDAPE---------------LIHDFLVNEKDASCK------- 190
Query: 221 SGLKSQFAYCMLIRIASRLLKETEDGHESPLFDFIESCLRNKH------EMVIYEAASAI 274
+ A+ MLI + D++ +C+ ++VI E +
Sbjct: 191 -----RNAFMMLIH-----------ADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKV 234
Query: 275 IHL-PNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTA---CNLDLE 330
H P+ AR + ++LQ S PA++Y A TL ++ P+A+ A C +DL
Sbjct: 235 CHANPSERARFIRCIYNLLQ----SSSPAVKYEAAGTLVTLS-SAPTAIKAAAQCYIDL- 288
Query: 331 NLITDSNRSIATLAITTLLKTGSESSVDRLMKQI 364
+I +S+ ++ + + L++ + +R+++ +
Sbjct: 289 -IIKESDNNVKLIVLDRLIELKEHPAHERVLQDL 321
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 37.0 bits (84), Expect = 0.080
Identities = 66/362 (18%), Positives = 143/362 (39%), Gaps = 27/362 (7%)
Query: 69 AFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSS-LTKDMTGKEDVYRGPAIRA 127
A F + + ++ T +R+ YL + DVI++T++ + KD++ G A+
Sbjct: 75 AAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTG 134
Query: 128 L-CRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISY-DVVKRWINEAQEAA 185
L C +T M ++ V ++ + + Y + ++ +E
Sbjct: 135 LSCFVTPDLARDLANDIM--TLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKL 192
Query: 186 SSDNIMVQYHALGVLYHL-RKNDR--LAVSKMLNKFTKSGLKSQFAYCMLIRIASRLLKE 242
+ VQ A+ V+ L R+N + L+++ + K S + ++ + E
Sbjct: 193 EDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLE 252
Query: 243 TEDGHE--SPLFDFIESCLRNKHEMVIYEAASAIIH--------LPNCTARELAPAVSVL 292
G + PL + I S ++YE + +I +PN +A + V L
Sbjct: 253 PRLGKKLIEPLTNLIHS---TSAMSLLYECVNTVIAVLISLSSGMPNHSA-SIQLCVQKL 308
Query: 293 QLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTG 352
++ L+Y + ++K+ HP +V + + + D + SI A+ L
Sbjct: 309 RILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMV 368
Query: 353 SESSVDRLMKQISSFVSEIS-----DEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRD 407
S+ ++ ++K++ + V + DE ++ S +Y ++ L + R
Sbjct: 369 SKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRL 428
Query: 408 DG 409
+G
Sbjct: 429 EG 430
Score = 34.3 bits (77), Expect = 0.52
Identities = 29/147 (19%), Positives = 63/147 (42%), Gaps = 6/147 (4%)
Query: 282 ARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIA 341
AR+LA + L S KP +R AV + KV +K+P ++ L+ + D + +
Sbjct: 144 ARDLANDIMTLM---SHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQ 200
Query: 342 TLAITTLLKTGSESSVDRLMKQISSF---VSEISDEFKVVVVQAISALCQKYPRKHSVMM 398
+ A+ + + + + L F S ++ + +++ AL PR ++
Sbjct: 201 SAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLI 260
Query: 399 TFLSNMLRDDGGFEYKRAIVDCIISIV 425
L+N++ V+ +I+++
Sbjct: 261 EPLTNLIHSTSAMSLLYECVNTVIAVL 287
>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
Length = 1236
Score = 35.8 bits (81), Expect = 0.18
Identities = 61/259 (23%), Positives = 107/259 (41%), Gaps = 38/259 (14%)
Query: 285 LAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKH-----PSAVTACNLDLENLITDSNRS 339
LA A+ +L F + ALR A + L+ +A PSAV A +L L+ +S+
Sbjct: 650 LAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMH 709
Query: 340 IATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQA---------ISAL---- 386
+A LA+ L T +++ L++ +SE+ + ++ A + AL
Sbjct: 710 VAQLAV-DFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTR 768
Query: 387 --CQKYPRKHSVMMTFLSNMLRDDGGFEYKR---AIVDCIISIVEENPESKEAGLAHL-C 440
C Y + S++ + D G +K+ ++ C+ ++ P+ + + L C
Sbjct: 769 PPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVC 828
Query: 441 EFIEDCEHTVLATKILHLLG------KEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSA 494
+ H+ K+L L GP K + + + +E VRAAA A
Sbjct: 829 D--ARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAV--LLEALGSPSEDVRAAASYA 884
Query: 495 LAKFGAQNESLLPSILVLL 513
L + GA + LP L L
Sbjct: 885 LGRVGAGS---LPDFLPFL 900
>gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]
Length = 1119
Score = 35.8 bits (81), Expect = 0.18
Identities = 61/259 (23%), Positives = 107/259 (41%), Gaps = 38/259 (14%)
Query: 285 LAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKH-----PSAVTACNLDLENLITDSNRS 339
LA A+ +L F + ALR A + L+ +A PSAV A +L L+ +S+
Sbjct: 557 LAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMH 616
Query: 340 IATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQA---------ISAL---- 386
+A LA+ L T +++ L++ +SE+ + ++ A + AL
Sbjct: 617 VAQLAV-DFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTR 675
Query: 387 --CQKYPRKHSVMMTFLSNMLRDDGGFEYKR---AIVDCIISIVEENPESKEAGLAHL-C 440
C Y + S++ + D G +K+ ++ C+ ++ P+ + + L C
Sbjct: 676 PPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVC 735
Query: 441 EFIEDCEHTVLATKILHLLG------KEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSA 494
+ H+ K+L L GP K + + + +E VRAAA A
Sbjct: 736 D--ARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAV--LLEALGSPSEDVRAAASYA 791
Query: 495 LAKFGAQNESLLPSILVLL 513
L + GA + LP L L
Sbjct: 792 LGRVGAGS---LPDFLPFL 807
>gi|169160755 PREDICTED: zyg-11 homolog A (C. elegans) [Homo
sapiens]
Length = 736
Score = 32.7 bits (73), Expect = 1.5
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 98 ISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGT---------------MLQAIER 142
+ E + IV T+++ +DV ++AL +TDG+ +Q +E
Sbjct: 513 VKELLAIVKQKTTENL---DDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLET 569
Query: 143 YMKQAIVDKVSSVSSS-ALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLY 201
+ + AI KV + ++ A V L ++ DV+K S + V Y A G++
Sbjct: 570 FSESAIQSKVLGLLNNIAEVRELSSKLVTEDVLKH----INSLLCSREMEVSYFAAGIIA 625
Query: 202 HLRKNDRLAVSKMLNKFT 219
HL + +L +S+ + T
Sbjct: 626 HLTSDRQLWISRDFQRRT 643
>gi|88948888 PREDICTED: zyg-11 homolog A (C. elegans) [Homo sapiens]
Length = 736
Score = 32.7 bits (73), Expect = 1.5
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 98 ISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGT---------------MLQAIER 142
+ E + IV T+++ +DV ++AL +TDG+ +Q +E
Sbjct: 513 VKELLAIVKQKTTENL---DDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLET 569
Query: 143 YMKQAIVDKVSSVSSS-ALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLY 201
+ + AI KV + ++ A V L ++ DV+K S + V Y A G++
Sbjct: 570 FSESAIQSKVLGLLNNIAEVRELSSKLVTEDVLKH----INSLLCSREMEVSYFAAGIIA 625
Query: 202 HLRKNDRLAVSKMLNKFT 219
HL + +L +S+ + T
Sbjct: 626 HLTSDRQLWISRDFQRRT 643
>gi|113408672 PREDICTED: zyg-11 homolog A [Homo sapiens]
Length = 759
Score = 32.7 bits (73), Expect = 1.5
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 98 ISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGT---------------MLQAIER 142
+ E + IV T+++ +DV ++AL +TDG+ +Q +E
Sbjct: 513 VKELLAIVKQKTTENL---DDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLET 569
Query: 143 YMKQAIVDKVSSVSSS-ALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLY 201
+ + AI KV + ++ A V L ++ DV+K S + V Y A G++
Sbjct: 570 FSESAIQSKVLGLLNNIAEVRELSSKLVTEDVLKH----INSLLCSREMEVSYFAAGIIA 625
Query: 202 HLRKNDRLAVSKMLNKFT 219
HL + +L +S+ + T
Sbjct: 626 HLTSDRQLWISRDFQRRT 643
>gi|226437632 zyg-11 homolog A [Homo sapiens]
Length = 759
Score = 32.7 bits (73), Expect = 1.5
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 98 ISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGT---------------MLQAIER 142
+ E + IV T+++ +DV ++AL +TDG+ +Q +E
Sbjct: 513 VKELLAIVKQKTTENL---DDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLET 569
Query: 143 YMKQAIVDKVSSVSSS-ALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLY 201
+ + AI KV + ++ A V L ++ DV+K S + V Y A G++
Sbjct: 570 FSESAIQSKVLGLLNNIAEVRELSSKLVTEDVLKH----INSLLCSREMEVSYFAAGIIA 625
Query: 202 HLRKNDRLAVSKMLNKFT 219
HL + +L +S+ + T
Sbjct: 626 HLTSDRQLWISRDFQRRT 643
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 31.6 bits (70), Expect = 3.3
Identities = 29/157 (18%), Positives = 65/157 (41%), Gaps = 14/157 (8%)
Query: 266 VIYEAASAIIH--------LPNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMK 317
++YE + +I +PN +A + V L++ L+Y + ++K+
Sbjct: 184 LLYECVNTVIAVLISLSSGMPNHSA-SIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKT 242
Query: 318 HPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEIS----- 372
HP +V + + + D + SI A+ L S+ ++ ++K++ + V +
Sbjct: 243 HPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYR 302
Query: 373 DEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRDDG 409
DE ++ S +Y ++ L + R +G
Sbjct: 303 DELLTKIIDICSQSNYQYITNFEWYISILVELTRLEG 339
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 30.8 bits (68), Expect = 5.7
Identities = 34/154 (22%), Positives = 65/154 (42%), Gaps = 27/154 (17%)
Query: 289 VSVLQLFCSSPKPALRYAAVRTLNKV---AMKHPSAVTACNLDLENLIT---DSN----- 337
+SV++ ++P P++R A+ LN + A H T N E+ +T +SN
Sbjct: 2177 ISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAG 2236
Query: 338 -RSIATLAITT---------------LLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQ 381
R I L IT+ LL GS + D ++ + +F S +++
Sbjct: 2237 LRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIAN 2296
Query: 382 AISALCQKYPRKHSVMMTFLSNMLRDDGGFEYKR 415
A ++L + +K + + L ++ + +KR
Sbjct: 2297 APTSLINIFSKKETKENILNALSLFENINYHFKR 2330
>gi|142976733 surface glycoprotein, Ig superfamily member [Homo
sapiens]
Length = 1264
Score = 30.8 bits (68), Expect = 5.7
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 3/88 (3%)
Query: 552 TVSVPGMEKALHQYTLEPSEKPFDMKSIPLAMAPVFEQKAEITLVATKPEKLAPSRQDIF 611
TV VPG E LH LEPS + + +A + E + + T EK A S+
Sbjct: 630 TVRVPGSENELHLAELEPSSL---YEVLMVARSAAGEGQPAMLTFRTSKEKTASSKNTQA 686
Query: 612 QEQLAAIPEFLNIGPLFKSSEPVQLTEA 639
IP++ + ++ V LT++
Sbjct: 687 SSPPVGIPKYPVVSEAANNNFGVVLTDS 714
>gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens]
Length = 522
Score = 30.4 bits (67), Expect = 7.4
Identities = 37/164 (22%), Positives = 66/164 (40%), Gaps = 30/164 (18%)
Query: 6 DKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQG---EHFG 62
+KK E+S S S+ F+HL +L E F L ++LY++ Q +H
Sbjct: 49 NKKLEKSSSASDVFEHLLAEDLLSEEDPF------------FLAELLYIIRQKKLLQHLN 96
Query: 63 TTEATEAFFAMTR----LFQS---------NDQTLRRMCYLTIKEMATISEDVIIVTSSL 109
T+ TR LF++ + + L+ M +L + + + L
Sbjct: 97 CTKEEVERLLPTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFL 156
Query: 110 TKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVS 153
K GK D + LC+ +L+ IE+Y ++ + V+
Sbjct: 157 EKQ--GKIDEDNLTCLEDLCKTVVPKLLRNIEKYKREKAIQIVT 198
>gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens]
Length = 521
Score = 30.4 bits (67), Expect = 7.4
Identities = 37/164 (22%), Positives = 66/164 (40%), Gaps = 30/164 (18%)
Query: 6 DKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQG---EHFG 62
+KK E+S S S+ F+HL +L E F L ++LY++ Q +H
Sbjct: 49 NKKLEKSSSASDVFEHLLAEDLLSEEDPF------------FLAELLYIIRQKKLLQHLN 96
Query: 63 TTEATEAFFAMTR----LFQS---------NDQTLRRMCYLTIKEMATISEDVIIVTSSL 109
T+ TR LF++ + + L+ M +L + + + L
Sbjct: 97 CTKEEVERLLPTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFL 156
Query: 110 TKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVS 153
K GK D + LC+ +L+ IE+Y ++ + V+
Sbjct: 157 EKQ--GKIDEDNLTCLEDLCKTVVPKLLRNIEKYKREKAIQIVT 198
>gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens]
Length = 479
Score = 30.4 bits (67), Expect = 7.4
Identities = 37/164 (22%), Positives = 66/164 (40%), Gaps = 30/164 (18%)
Query: 6 DKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQG---EHFG 62
+KK E+S S S+ F+HL +L E F L ++LY++ Q +H
Sbjct: 49 NKKLEKSSSASDVFEHLLAEDLLSEEDPF------------FLAELLYIIRQKKLLQHLN 96
Query: 63 TTEATEAFFAMTR----LFQS---------NDQTLRRMCYLTIKEMATISEDVIIVTSSL 109
T+ TR LF++ + + L+ M +L + + + L
Sbjct: 97 CTKEEVERLLPTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFL 156
Query: 110 TKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVS 153
K GK D + LC+ +L+ IE+Y ++ + V+
Sbjct: 157 EKQ--GKIDEDNLTCLEDLCKTVVPKLLRNIEKYKREKAIQIVT 198
>gi|110630018 eukaryotic translation initiation factor 4 gamma, 2
isoform 2 [Homo sapiens]
Length = 869
Score = 30.4 bits (67), Expect = 7.4
Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 567 LEPSEKPFDMKSIPLAMAPVFEQKAEITLVATKPEKLA----PSRQDIFQEQLAAIPEFL 622
+ PS +P ++ PL P K L+ KP K + PS++++ + + E+L
Sbjct: 459 IPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYL 518
Query: 623 NIG 625
N G
Sbjct: 519 NSG 521
>gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
isoform 1 [Homo sapiens]
Length = 907
Score = 30.4 bits (67), Expect = 7.4
Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 567 LEPSEKPFDMKSIPLAMAPVFEQKAEITLVATKPEKLA----PSRQDIFQEQLAAIPEFL 622
+ PS +P ++ PL P K L+ KP K + PS++++ + + E+L
Sbjct: 497 IPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYL 556
Query: 623 NIG 625
N G
Sbjct: 557 NSG 559
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,228,156
Number of Sequences: 37866
Number of extensions: 1307163
Number of successful extensions: 3191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 3149
Number of HSP's gapped (non-prelim): 60
length of query: 871
length of database: 18,247,518
effective HSP length: 111
effective length of query: 760
effective length of database: 14,044,392
effective search space: 10673737920
effective search space used: 10673737920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.