Search of human proteins with 4557727

Search of human proteins with 4557727

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557727 lipoprotein lipase precursor [Homo sapiens]
         (475 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557727 lipoprotein lipase precursor [Homo sapiens]                971   0.0  
gi|5174497 endothelial lipase precursor [Homo sapiens]                446   e-125
gi|194097335 lipase C precursor [Homo sapiens]                        397   e-110
gi|10835000 pancreatic lipase precursor [Homo sapiens]                195   7e-50
gi|5453920 pancreatic lipase-related protein 1 [Homo sapiens]         194   1e-49
gi|106507261 pancreatic lipase-related protein 2 [Homo sapiens]       186   5e-47
gi|190341077 pancreatic lipase-related protein 3 [Homo sapiens]       168   9e-42
gi|21245106 lipase, member H precursor [Homo sapiens]                 164   2e-40
gi|39752679 lipase, member I [Homo sapiens]                           161   1e-39
gi|7706661 phospholipase A1 member A [Homo sapiens]                   149   7e-36
gi|148833508 notch1 preproprotein [Homo sapiens]                       33   0.43 
gi|24308171 zinc finger protein 280C [Homo sapiens]                    32   1.6  
gi|14149712 C1q and tumor necrosis factor related protein 5 prec...    30   3.7  
gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens]       30   6.3  
gi|38683855 pentatricopeptide repeat domain 3 [Homo sapiens]           29   8.2  

>gi|4557727 lipoprotein lipase precursor [Homo sapiens]
          Length = 475

 Score =  971 bits (2511), Expect = 0.0
 Identities = 475/475 (100%), Positives = 475/475 (100%)

Query: 1   MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALRTPEDTAEDTCHLIPGV 60
           MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALRTPEDTAEDTCHLIPGV
Sbjct: 1   MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALRTPEDTAEDTCHLIPGV 60

Query: 61  AESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEH 120
           AESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEH
Sbjct: 61  AESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEH 120

Query: 121 YPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRIT 180
           YPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRIT
Sbjct: 121 YPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRIT 180

Query: 181 GLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQ 240
           GLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQ
Sbjct: 181 GLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQ 240

Query: 241 PGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKG 300
           PGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKG
Sbjct: 241 PGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKG 300

Query: 301 LCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQ 360
           LCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQ
Sbjct: 301 LCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQ 360

Query: 361 AFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDW 420
           AFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDW
Sbjct: 361 AFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDW 420

Query: 421 WSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG 475
           WSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG
Sbjct: 421 WSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG 475


>gi|5174497 endothelial lipase precursor [Homo sapiens]
          Length = 500

 Score =  446 bits (1146), Expect = e-125
 Identities = 216/441 (48%), Positives = 305/441 (69%), Gaps = 18/441 (4%)

Query: 40  KFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAAL 99
           +F LRT +D   + C+L  G ++ +  C FN ++KTF +IHGWT++G++E+W+ KLV+AL
Sbjct: 50  RFNLRTSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSAL 109

Query: 100 YKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYS 159
           + RE D+NV+VVDWL  A + Y  +   T++VG  +AR ++W++E+ ++ L NVHL+GYS
Sbjct: 110 HTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYS 169

Query: 160 LGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGR 219
           LGAH AG AG+     V RITGLDPAGP FE A+   RLSPDDADFVDVLHT+TR S G 
Sbjct: 170 LGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTR-SFGL 228

Query: 220 SIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSL 279
           SIGIQ PVGH+DIYPNGG FQPGC + + +  IA    G + ++VKC HER++HLF+DSL
Sbjct: 229 SIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIA---YGTITEVVKCEHERAVHLFVDSL 285

Query: 280 LNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYK 339
           +N++ PS A++C+    F+KG+CLSCRKNRCN++GY   K+R KR+SKMYLKTR+ MP++
Sbjct: 286 VNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFR 345

Query: 340 VFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPE-VSTNKTYSFLIYTEVD 398
           V+HYQ+KIH    ++       F ++LYGT A+S+ +P  + E +  N T +FL+YTE D
Sbjct: 346 VYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEED 405

Query: 399 IGELLMLKLKWKSDSYFSWSDWWS----------SPG--FAIQKIRVKAGETQKKVIFCS 446
           +G+LL ++L W+  S  SW + W           +PG    I++IRVK+GETQ+K+ FC+
Sbjct: 406 LGDLLKIQLTWEGASQ-SWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLTFCT 464

Query: 447 REKVSHLQKGKAPAVFVKCHD 467
            +  +          F KC D
Sbjct: 465 EDPENTSISPGRELWFRKCRD 485


>gi|194097335 lipase C precursor [Homo sapiens]
          Length = 499

 Score =  397 bits (1019), Expect = e-110
 Identities = 201/436 (46%), Positives = 279/436 (63%), Gaps = 18/436 (4%)

Query: 54  CHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDS--NVIVV 111
           C +     +++  C FN S    M+IHGW+V G+ E+W+ ++VAAL K +P    NV +V
Sbjct: 62  CQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAAL-KSQPAQPVNVGLV 120

Query: 112 DWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSL 171
           DW++ A +HY ++   T+LVG++VA  + W+EE       +VHL+GYSLGAH +G AGS 
Sbjct: 121 DWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSS 180

Query: 172 TN--KKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGH 229
                K+ RITGLD AGP FE +   +RLSPDDA+FVD +HTFTR   G S+GI++P+GH
Sbjct: 181 IGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGH 240

Query: 230 VDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAY 289
            D YPNGG+FQPGC+  E  R IA+ G   + Q +KCSHERS+HLFIDSLL+    S AY
Sbjct: 241 YDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAY 300

Query: 290 RCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHF 349
            C    +F +GLCLSC+K RCN LGY + +    +S +++L TR+Q P+KV+HYQ KI F
Sbjct: 301 PCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQF 360

Query: 350 SGTESETHTNQAFEISLYGTVAESENIPFTLPE-VSTNKTYSFLIYTEVDIGELLMLKLK 408
              ++ET     F +SL GT  + + IP TL + +++NKTYSFLI  +VDIGEL+M+K K
Sbjct: 361 I-NQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFK 419

Query: 409 WKSDSYFS-----------WSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGK 457
           W++ + ++           WS      G  ++ IRVKAGETQ+++ FCS      L +  
Sbjct: 420 WENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPT 479

Query: 458 APAVFVKCHDKSLNKK 473
              +FVKC  KS   K
Sbjct: 480 QEKIFVKCEIKSKTSK 495


>gi|10835000 pancreatic lipase precursor [Homo sapiens]
          Length = 465

 Score =  195 bits (496), Expect = 7e-50
 Identities = 129/420 (30%), Positives = 205/420 (48%), Gaps = 20/420 (4%)

Query: 36  DIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKL 95
           D+ ++F L T E+   +    +   + S++  +F  + KT  +IHG+   G  E+W+  +
Sbjct: 50  DVNTRFLLYTNENP--NNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGE-ENWLANV 106

Query: 96  VAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHL 155
              L+K E   N I VDW   ++  Y  ++   ++VG +VA F+ +++  F Y   NVH+
Sbjct: 107 CKNLFKVE-SVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHV 165

Query: 156 LGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRG 215
           +G+SLGAHAAG AG  TN  + RITGLDPA P F+      RL P DA FVDV+HT    
Sbjct: 166 IGHSLGAHAAGEAGRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAP 225

Query: 216 -SPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGD-VDQLVKCSHERSIH 273
             P    G+ + VGH+D +PNGG   PGC      +++   G+ +       C+H RS  
Sbjct: 226 IVPNLGFGMSQVVGHLDFFPNGGVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYK 285

Query: 274 LFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRS---SKMYL 330
            + DS++N +     + C+S   F    C  C    C  +G+  ++   K +    K YL
Sbjct: 286 YYTDSIVNPDG-FAGFPCASYNVFTANKCFPCPSGGCPQMGHYADRYPGKTNDVGQKFYL 344

Query: 331 KTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYS 390
            T     +  + Y+V +  SG +   H      +SL+G    S+        +  + T+S
Sbjct: 345 DTGDASNFARWRYKVSVTLSGKKVTGH----ILVSLFGNKGNSKQYEIFKGTLKPDSTHS 400

Query: 391 FLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKV 450
               ++VD+G+L M+K  W ++         + P     KI V+     K+  FCS E V
Sbjct: 401 NEFDSDVDVGDLQMVKFIWYNNVINP-----TLPRVGASKIIVET-NVGKQFNFCSPETV 454


>gi|5453920 pancreatic lipase-related protein 1 [Homo sapiens]
          Length = 467

 Score =  194 bits (493), Expect = 1e-49
 Identities = 132/419 (31%), Positives = 205/419 (48%), Gaps = 19/419 (4%)

Query: 37  IESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLV 96
           I ++F L T E+       L+   + ++   +F    KT  +IHG+   G  ESWV  + 
Sbjct: 52  IGTRFLLYTNENPNNFQILLLSDPS-TIEASNFQMDRKTRFIIHGFIDKGD-ESWVTDMC 109

Query: 97  AALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLL 156
             L++ E + N I VDW   +Q  Y  +A   ++VG  VA+ ++ +  E++YP   VHL+
Sbjct: 110 KKLFEVE-EVNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLI 168

Query: 157 GYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRG- 215
           G+SLGAH AG AGS T   ++RITGLDP   +FE      RL P DADFVDV+HT     
Sbjct: 169 GHSLGAHVAGEAGSKT-PGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPL 227

Query: 216 SPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGL-GDVDQLVKCSHERSIHL 274
            P    G  + +GH+D +PNGG   PGC      +++   G+       V C+H RS   
Sbjct: 228 IPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKY 287

Query: 275 FIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRS---SKMYLK 331
           +++S+LN +    AY C+S ++FE   C  C    C  +G+  +K   + S    K +L 
Sbjct: 288 YLESILNPDG-FAAYPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFFLN 346

Query: 332 TRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSF 391
           T     +  + Y V I  SG    T T Q  +++L+G    +         +    T+S+
Sbjct: 347 TGEASNFARWRYGVSITLSG---RTATGQ-IKVALFGNKGNTHQYSIFRGILKPGSTHSY 402

Query: 392 LIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKV 450
               ++D+G +  +K  W ++         + P     KI V+ GE +    FCS + V
Sbjct: 403 EFDAKLDVGTIEKVKFLWNNNVINP-----TLPKVGATKITVQKGEEKTVYNFCSEDTV 456


>gi|106507261 pancreatic lipase-related protein 2 [Homo sapiens]
          Length = 470

 Score =  186 bits (471), Expect = 5e-47
 Identities = 123/421 (29%), Positives = 203/421 (48%), Gaps = 19/421 (4%)

Query: 36  DIESKFALRTPEDTAEDTCHLIPGVA-ESVATCHFNHSSKTFMVIHGWTVTGMYESWVPK 94
           DI+++F L T E+   +   LI G   +++   +F    KT  +IHG+ +    +SW   
Sbjct: 52  DIDTRFLLYTNENP--NNFQLITGTEPDTIEASNFQLDRKTRFIIHGF-LDKAEDSWPSD 108

Query: 95  LVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVH 154
           +   +++ E   N I VDW   ++  Y  +    ++VG + A  I  +  +  Y L++VH
Sbjct: 109 MCKKMFEVEK-VNCICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQALSTQLGYSLEDVH 167

Query: 155 LLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTR 214
           ++G+SLGAH A  AG     +V RITGLDPAGP F+      RL P DA FVDV+HT + 
Sbjct: 168 VIGHSLGAHTAAEAGRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSS 227

Query: 215 G-SPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGD-VDQLVKCSHERSI 272
              P    G+ + VGH+D +PNGG   PGC       +    G+ + +   V C+H RS 
Sbjct: 228 PIVPSLGFGMSQKVGHLDFFPNGGKEMPGCKKNVLSTITDIDGIWEGIGGFVSCNHLRSF 287

Query: 273 HLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSS---KMY 329
             +  S+LN +     Y C+S + F++  C  C    C  +G+  ++ + K S+     +
Sbjct: 288 EYYSSSVLNPDG-FLGYPCASYDEFQESKCFPCPAEGCPKMGHYADQFKGKTSAVEQTFF 346

Query: 330 LKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTY 389
           L T     +  + Y+V +  SG E     N    I+LYG+   S+        +  + ++
Sbjct: 347 LNTGESGNFTSWRYKVSVTLSGKEK---VNGYIRIALYGSNENSKQYEIFKGSLKPDASH 403

Query: 390 SFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREK 449
           +  I  + ++G++  +K  W            S P     +I V++GE   +  FCS + 
Sbjct: 404 TCAIDVDFNVGKIQKVKFLWNKRGIN-----LSEPKLGASQITVQSGEDGTEYNFCSSDT 458

Query: 450 V 450
           V
Sbjct: 459 V 459


>gi|190341077 pancreatic lipase-related protein 3 [Homo sapiens]
          Length = 467

 Score =  168 bits (426), Expect = 9e-42
 Identities = 118/395 (29%), Positives = 188/395 (47%), Gaps = 22/395 (5%)

Query: 61  AESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEH 120
           + ++   +F     T + I GW   G    W   +   L + E D N I +DW++ ++E 
Sbjct: 75  SSTIQASYFGTDKITRINIAGWKTDG---KWQRDMCNVLLQLE-DINCINLDWINGSRE- 129

Query: 121 YPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRIT 180
           Y  +    ++VG +VA FI+ + ++F Y    VHL+G+SLGAH AG AGS     + RIT
Sbjct: 130 YIHAVNNLRVVGAEVAYFIDVLMKKFEYSPSKVHLIGHSLGAHLAGEAGSRI-PGLGRIT 188

Query: 181 GLDPAGPNFEYAEAPSRLSPDDADFVDVLHT-FTRGSPGRSIGIQKPVGHVDIYPNGGTF 239
           GLDPAGP F       RL P DA+FVDV+HT   R      +G     GH+D YPNGG  
Sbjct: 189 GLDPAGPFFHNTPKEVRLDPSDANFVDVIHTNAARILFELGVGTIDACGHLDFYPNGGKH 248

Query: 240 QPGCN--IGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAF 297
            PGC   I   ++        ++     C+H RS   + +S+LN +    AY C S  +F
Sbjct: 249 MPGCEDLITPLLKFNFNAYKKEMASFFDCNHARSYQFYAESILNPD-AFIAYPCRSYTSF 307

Query: 298 EKGLCLSCRKNRCNNLGYEINKVRAK----RSSKMYLKTRSQMPYKVFHYQVKIHFSGTE 353
           + G C  C K  C  +G+  ++   K      S  +L T S  P+  + +++ +  SG+E
Sbjct: 308 KAGNCFFCSKEGCPTMGHFADRFHFKNMKTNGSHYFLNTGSLSPFARWRHKLSVKLSGSE 367

Query: 354 SETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDS 413
               T     + + G V ++        ++    TY+ LI  +V++G +  ++  WK   
Sbjct: 368 V---TQGTVFLRVGGAVRKTGEFAIVSGKLEPGMTYTKLIDADVNVGNITSVQFIWKKHL 424

Query: 414 YFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSRE 448
           +       S      + +   +G+   K  FCS++
Sbjct: 425 FED-----SQNKLGAEMVINTSGKYGYKSTFCSQD 454


>gi|21245106 lipase, member H precursor [Homo sapiens]
          Length = 451

 Score =  164 bits (415), Expect = 2e-40
 Identities = 108/295 (36%), Positives = 156/295 (52%), Gaps = 28/295 (9%)

Query: 63  SVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEH-Y 121
           S A  + N + KT  ++HG+  TG    W+  LV  L   E D NV+VVDW   A    Y
Sbjct: 59  SSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVE-DMNVVVVDWNRGATTLIY 117

Query: 122 PVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITG 181
             ++  T+ V   +  FI+ M  E    LD+++++G SLGAH +G  G + +  + RITG
Sbjct: 118 THASSKTRKVAMVLKEFIDQMLAE-GASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITG 176

Query: 182 LDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQP 241
           LDPAGP F       RL P DA FVDV+H+ T      ++G ++P+G++D YPNGG  QP
Sbjct: 177 LDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDT-----DALGYKEPLGNIDFYPNGGLDQP 231

Query: 242 GCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGL 301
           GC          +  LG   Q  KC H+RS++L++ S L E     AY C S + +  G 
Sbjct: 232 GC---------PKTILGGF-QYFKCDHQRSVYLYLSS-LRESCTITAYPCDSYQDYRNGK 280

Query: 302 CLSC---RKNRCNNLGYEINK----VRAK--RSSKMYLKTRSQMPYKVFHYQVKI 347
           C+SC   +K  C  LGY  +     +R K    +K +  T  + P+ ++HY V I
Sbjct: 281 CVSCGTSQKESCPLLGYYADNWKDHLRGKDPPMTKAFFDTAEESPFCMYHYFVDI 335


>gi|39752679 lipase, member I [Homo sapiens]
          Length = 481

 Score =  161 bits (407), Expect = 1e-39
 Identities = 100/293 (34%), Positives = 148/293 (50%), Gaps = 31/293 (10%)

Query: 68  HFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEH-YPVSAG 126
           +FN   KT  +IHG+   G    W+   V  L   E D NVIVVDW   A    Y  +  
Sbjct: 90  NFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEE-DMNVIVVDWSRGATTFIYNRAVK 148

Query: 127 YTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAG 186
            T+ V   ++  I  + +     LDN H +G SLGAH +G  G + + ++ RITGLDPAG
Sbjct: 149 NTRKVAVSLSVHIKNLLKH-GASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAG 207

Query: 187 PNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIG 246
           P F      SRL   DA FVDV+H+ + G     +GIQ+P+GH+D YPNGG  QPGC   
Sbjct: 208 PRFSRKPPYSRLDYTDAKFVDVIHSDSNG-----LGIQEPLGHIDFYPNGGNKQPGC--- 259

Query: 247 EAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSC- 305
                   + +    Q +KC+H+R++HLF+ SL    N   ++ C S + ++  LC+ C 
Sbjct: 260 -------PKSIFSGIQFIKCNHQRAVHLFMASLETNCN-FISFPCRSYKDYKTSLCVDCD 311

Query: 306 --RKNRCNNLGYEINKVRAKRSSKM---------YLKTRSQMPYKVFHYQVKI 347
             ++  C  LGY+    +     +M         +L T    P+  +++ + I
Sbjct: 312 CFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSI 364


>gi|7706661 phospholipase A1 member A [Homo sapiens]
          Length = 456

 Score =  149 bits (375), Expect = 7e-36
 Identities = 103/320 (32%), Positives = 158/320 (49%), Gaps = 28/320 (8%)

Query: 36  DIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKL 95
           D++ +F L  P + +   C  +   +  +    FN +  T ++IHG+ V G   SW+   
Sbjct: 48  DLKVQFLLFVPSNPS---CGQLVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTF 104

Query: 96  VAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHL 155
           +  L  R  ++NVI VDW+  +   Y  +      +  +++ F+N +         ++H+
Sbjct: 105 IRTLL-RATNANVIAVDWIYGSTGVYFSAVKNVIKLSLEISLFLNKLLV-LGVSESSIHI 162

Query: 156 LGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRG 215
           +G SLGAH  G+ G L   ++ +ITGLDPAGP +  A    RL   DA FV+ +HT T  
Sbjct: 163 IGVSLGAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDT-- 220

Query: 216 SPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLF 275
               ++GI+ PVGHVD + NGG  QPGC            G       + C H R++HL+
Sbjct: 221 ---DNLGIRIPVGHVDYFVNGGQDQPGC------PTFFYAGY----SYLICDHMRAVHLY 267

Query: 276 IDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKN---RCNNLG-YEINKVRAK---RSSKM 328
           I +L N   P  A+ C+S +AF  G CL C       C  +G  E   V+ +   +  K+
Sbjct: 268 ISALEN-SCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQGGVKIEPLPKEVKV 326

Query: 329 YLKTRSQMPYKVFHYQVKIH 348
           YL T S  PY + H  V+ H
Sbjct: 327 YLLTTSSAPYCMHHSLVEFH 346


>gi|148833508 notch1 preproprotein [Homo sapiens]
          Length = 2555

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 11/32 (34%), Positives = 17/32 (53%)

Query: 52  DTCHLIPGVAESVATCHFNHSSKTFMVIHGWT 83
           D C L+P   ++  TCH  H     + ++GWT
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNCVCVNGWT 328


>gi|24308171 zinc finger protein 280C [Homo sapiens]
          Length = 737

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 14/57 (24%), Positives = 29/57 (50%)

Query: 306 RKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAF 362
           ++NR N +   +  +R +R     ++  S++     H+ + IH S  +  T+ N+AF
Sbjct: 598 QRNRKNKMSLALKNIRCRRGIHKCIECHSKIKDFASHFSIYIHCSFCKYNTNCNKAF 654


>gi|14149712 C1q and tumor necrosis factor related protein 5
           precursor [Homo sapiens]
          Length = 243

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 4/39 (10%)

Query: 393 IYTEVDIGELLMLKLKWKSDSYFS----WSDWWSSPGFA 427
           ++ +V +G+ + +    K+DS FS    +SDW SSP FA
Sbjct: 205 VWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA 243


>gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens]
          Length = 701

 Score = 29.6 bits (65), Expect = 6.3
 Identities = 17/81 (20%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 343 YQVKIHFSGTESETHTNQAFEISLYGTVAESEN--IPFTLPEVSTNKTYSFLIYTEVDIG 400
           Y+V++  +GT+  + T  +  +++ GT  ES    +     + +T     + +    D+G
Sbjct: 4   YKVRVA-TGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQDLG 62

Query: 401 ELLMLKLKWKSDSYFSWSDWW 421
           EL++++L  +  ++F    W+
Sbjct: 63  ELIIIRLHKERYAFFPKDPWY 83


>gi|38683855 pentatricopeptide repeat domain 3 [Homo sapiens]
          Length = 689

 Score = 29.3 bits (64), Expect = 8.2
 Identities = 13/36 (36%), Positives = 18/36 (50%)

Query: 59 GVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPK 94
          G+ E   +C F   S T   + G  VTG+ E  +PK
Sbjct: 26 GLCEQARSCRFYSGSATLSKVEGTDVTGIEEVVIPK 61


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,345,987
Number of Sequences: 37866
Number of extensions: 833759
Number of successful extensions: 1814
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1760
Number of HSP's gapped (non-prelim): 16
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.