Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4557603
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557603 gamma-aminobutyric acid A receptor, alpha 3
precursor [Homo sapiens]
(492 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 995 0.0
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 647 0.0
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 640 0.0
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 640 0.0
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 639 0.0
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 639 0.0
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 639 0.0
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 639 0.0
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 639 0.0
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 639 0.0
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 639 0.0
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 517 e-146
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 510 e-144
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 384 e-107
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 383 e-106
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 379 e-105
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform... 362 e-100
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 355 7e-98
gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p... 304 1e-82
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 276 2e-74
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 276 2e-74
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 276 4e-74
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 271 1e-72
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 271 1e-72
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 270 2e-72
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 270 2e-72
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 270 2e-72
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 270 2e-72
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 269 4e-72
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 268 8e-72
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 995 bits (2572), Expect = 0.0
Identities = 492/492 (100%), Positives = 492/492 (100%)
Query: 1 MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS 60
MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
Sbjct: 1 MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS 60
Query: 61 TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ 120
TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
Sbjct: 61 TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ 120
Query: 121 TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL 180
TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL
Sbjct: 121 TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL 180
Query: 181 YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL 240
YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL
Sbjct: 181 YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL 240
Query: 241 NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN 300
NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
Sbjct: 241 NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN 300
Query: 301 RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN 360
RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN
Sbjct: 301 RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN 360
Query: 361 YFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGA 420
YFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGA
Sbjct: 361 YFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGA 420
Query: 421 APSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN 480
APSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN
Sbjct: 421 APSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN 480
Query: 481 RESAIKGMIRKQ 492
RESAIKGMIRKQ
Sbjct: 481 RESAIKGMIRKQ 492
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 647 bits (1669), Expect = 0.0
Identities = 321/441 (72%), Positives = 357/441 (80%), Gaps = 12/441 (2%)
Query: 47 GLSPKHAPDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVS 106
G S + D++ DNITIFTRILD LLDGYDNRLRPGLG+ +T+V+TDIYVTSFGPVS
Sbjct: 29 GFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVS 88
Query: 107 DTDMEYTIDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTT 166
DT+MEYTIDVFFRQ+W DERL+F GPM+ LPLNNLLASKIWTPDTFFHNGKKS+AHNMTT
Sbjct: 89 DTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTT 148
Query: 167 PNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLG 226
PNKLLRL D+GTLLYTMRLTI AECPM LEDFPMD HACPLKFGSYAY +EVVY WT G
Sbjct: 149 PNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNG 208
Query: 227 KNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPC 286
KSV VA+DGSRLNQY L+G VGTE I +STGEY +MT HFHLKRKIGYFVIQTYLPC
Sbjct: 209 STKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPC 268
Query: 287 IMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCY 346
IMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCY
Sbjct: 269 IMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCY 328
Query: 347 AFVFSALIEFATVNYFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPIN 406
AFVFSALIEFATVNYFTKR WAW+GKK EA ++KKK K++ F ++P N
Sbjct: 329 AFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREVI-LNKSTNAFTTGKMSHPPN 387
Query: 407 LAKDTEFSTISKGAAPSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVL 466
+ K+ S+T ++ P +S KTYNS+SK+DK+SRI+FPVL
Sbjct: 388 IPKEQ--------TPAGTSNTTSVSVKPSEEKTSES---KKTYNSISKIDKMSRIVFPVL 436
Query: 467 FAIFNLVYWATYVNRESAIKG 487
F FNLVYWATY+NRE IKG
Sbjct: 437 FGTFNLVYWATYLNREPVIKG 457
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 640 bits (1651), Expect = 0.0
Identities = 321/429 (74%), Positives = 352/429 (82%), Gaps = 15/429 (3%)
Query: 58 DDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVF 117
D++ +NITIFTRILDRLLDGYDNRLRPGLGD++TEV T+IYVTSFGPVSDTDMEYTIDVF
Sbjct: 33 DEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVF 92
Query: 118 FRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNG 177
FRQ W DERLKF GPM IL LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+ D+G
Sbjct: 93 FRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDG 152
Query: 178 TLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDG 237
TLLYTMRLT+ AECPMHLEDFPMD H+CPLKFGSYAYTT+EV Y WT + SV+VA DG
Sbjct: 153 TLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDG 212
Query: 238 SRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSF 297
SRLNQYDLLG +G E I+SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVSF
Sbjct: 213 SRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSF 272
Query: 298 WLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFA 357
WLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFA
Sbjct: 273 WLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFA 332
Query: 358 TVNYFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTIS 417
TVNYFTKR WAW+GK V KK A + + + Y NL+KD STIS
Sbjct: 333 TVNYFTKRGWAWDGKSVVN----DKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTIS 388
Query: 418 KGAAPSASSTPTIIASPKATYVQDSPTET-KTYNSVSKVDKISRIIFPVLFAIFNLVYWA 476
K A +TP P ++ P E KT+NSVSK+D++SRI+FPVLF FNLVYWA
Sbjct: 389 KSA-----TTPEPNKKP-----ENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWA 438
Query: 477 TYVNRESAI 485
TY+NRE +
Sbjct: 439 TYLNREPVL 447
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 640 bits (1651), Expect = 0.0
Identities = 321/429 (74%), Positives = 352/429 (82%), Gaps = 15/429 (3%)
Query: 58 DDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVF 117
D++ +NITIFTRILDRLLDGYDNRLRPGLGD++TEV T+IYVTSFGPVSDTDMEYTIDVF
Sbjct: 33 DEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVF 92
Query: 118 FRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNG 177
FRQ W DERLKF GPM IL LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+ D+G
Sbjct: 93 FRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDG 152
Query: 178 TLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDG 237
TLLYTMRLT+ AECPMHLEDFPMD H+CPLKFGSYAYTT+EV Y WT + SV+VA DG
Sbjct: 153 TLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDG 212
Query: 238 SRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSF 297
SRLNQYDLLG +G E I+SSTGEY VMT HFHLKRKIGYFVIQTYLPCIMTVILSQVSF
Sbjct: 213 SRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSF 272
Query: 298 WLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFA 357
WLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFA
Sbjct: 273 WLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFA 332
Query: 358 TVNYFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTIS 417
TVNYFTKR WAW+GK V KK A + + + Y NL+KD STIS
Sbjct: 333 TVNYFTKRGWAWDGKSVVN----DKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTIS 388
Query: 418 KGAAPSASSTPTIIASPKATYVQDSPTET-KTYNSVSKVDKISRIIFPVLFAIFNLVYWA 476
K A +TP P ++ P E KT+NSVSK+D++SRI+FPVLF FNLVYWA
Sbjct: 389 KSA-----TTPEPNKKP-----ENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWA 438
Query: 477 TYVNRESAI 485
TY+NRE +
Sbjct: 439 TYLNREPVL 447
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 639 bits (1648), Expect = 0.0
Identities = 324/436 (74%), Positives = 357/436 (81%), Gaps = 17/436 (3%)
Query: 54 PDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYT 113
P + D+ DN T+FTRILDRLLDGYDNRLRPGLG+ VTEVKTDI+VTSFGPVSD DMEYT
Sbjct: 29 PSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYT 88
Query: 114 IDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRL 173
IDVFFRQ+W DERLKF GPM +L LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
Query: 174 VDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEV 233
++GTLLYTMRLT+ AECPMHLEDFPMD HACPLKFGSYAYT AEVVY WT +SV V
Sbjct: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
Query: 234 AQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 293
A+DGSRLNQYDLLG V + I++SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS
Sbjct: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
Query: 294 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 353
QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL
Sbjct: 269 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 328
Query: 354 IEFATVNYFTKRSWAWEGKK-VPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-DT 411
IEFATVNYFTKR +AW+GK VPE K K P K + T+ T+Y NLA+ D
Sbjct: 329 IEFATVNYFTKRGYAWDGKSVVPE----KPKKVKDPLIKKNNTYAPTATSYTPNLARGDP 384
Query: 412 EFSTISKGAAPSASSTPTIIASPKATYVQDSPTE-TKTYNSVSKVDKISRIIFPVLFAIF 470
+TI+K A PK + P E KT+NSVSK+D++SRI FP+LF IF
Sbjct: 385 GLATIAKSAT----------IEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIF 434
Query: 471 NLVYWATYVNRESAIK 486
NLVYWATY+NRE +K
Sbjct: 435 NLVYWATYLNREPQLK 450
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 639 bits (1648), Expect = 0.0
Identities = 324/436 (74%), Positives = 357/436 (81%), Gaps = 17/436 (3%)
Query: 54 PDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYT 113
P + D+ DN T+FTRILDRLLDGYDNRLRPGLG+ VTEVKTDI+VTSFGPVSD DMEYT
Sbjct: 29 PSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYT 88
Query: 114 IDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRL 173
IDVFFRQ+W DERLKF GPM +L LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
Query: 174 VDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEV 233
++GTLLYTMRLT+ AECPMHLEDFPMD HACPLKFGSYAYT AEVVY WT +SV V
Sbjct: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
Query: 234 AQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 293
A+DGSRLNQYDLLG V + I++SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS
Sbjct: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
Query: 294 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 353
QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL
Sbjct: 269 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 328
Query: 354 IEFATVNYFTKRSWAWEGKK-VPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-DT 411
IEFATVNYFTKR +AW+GK VPE K K P K + T+ T+Y NLA+ D
Sbjct: 329 IEFATVNYFTKRGYAWDGKSVVPE----KPKKVKDPLIKKNNTYAPTATSYTPNLARGDP 384
Query: 412 EFSTISKGAAPSASSTPTIIASPKATYVQDSPTE-TKTYNSVSKVDKISRIIFPVLFAIF 470
+TI+K A PK + P E KT+NSVSK+D++SRI FP+LF IF
Sbjct: 385 GLATIAKSAT----------IEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIF 434
Query: 471 NLVYWATYVNRESAIK 486
NLVYWATY+NRE +K
Sbjct: 435 NLVYWATYLNREPQLK 450
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 639 bits (1648), Expect = 0.0
Identities = 324/436 (74%), Positives = 357/436 (81%), Gaps = 17/436 (3%)
Query: 54 PDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYT 113
P + D+ DN T+FTRILDRLLDGYDNRLRPGLG+ VTEVKTDI+VTSFGPVSD DMEYT
Sbjct: 29 PSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYT 88
Query: 114 IDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRL 173
IDVFFRQ+W DERLKF GPM +L LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
Query: 174 VDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEV 233
++GTLLYTMRLT+ AECPMHLEDFPMD HACPLKFGSYAYT AEVVY WT +SV V
Sbjct: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
Query: 234 AQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 293
A+DGSRLNQYDLLG V + I++SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS
Sbjct: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
Query: 294 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 353
QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL
Sbjct: 269 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 328
Query: 354 IEFATVNYFTKRSWAWEGKK-VPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-DT 411
IEFATVNYFTKR +AW+GK VPE K K P K + T+ T+Y NLA+ D
Sbjct: 329 IEFATVNYFTKRGYAWDGKSVVPE----KPKKVKDPLIKKNNTYAPTATSYTPNLARGDP 384
Query: 412 EFSTISKGAAPSASSTPTIIASPKATYVQDSPTE-TKTYNSVSKVDKISRIIFPVLFAIF 470
+TI+K A PK + P E KT+NSVSK+D++SRI FP+LF IF
Sbjct: 385 GLATIAKSAT----------IEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIF 434
Query: 471 NLVYWATYVNRESAIK 486
NLVYWATY+NRE +K
Sbjct: 435 NLVYWATYLNREPQLK 450
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 639 bits (1648), Expect = 0.0
Identities = 324/436 (74%), Positives = 357/436 (81%), Gaps = 17/436 (3%)
Query: 54 PDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYT 113
P + D+ DN T+FTRILDRLLDGYDNRLRPGLG+ VTEVKTDI+VTSFGPVSD DMEYT
Sbjct: 29 PSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYT 88
Query: 114 IDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRL 173
IDVFFRQ+W DERLKF GPM +L LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
Query: 174 VDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEV 233
++GTLLYTMRLT+ AECPMHLEDFPMD HACPLKFGSYAYT AEVVY WT +SV V
Sbjct: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
Query: 234 AQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 293
A+DGSRLNQYDLLG V + I++SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS
Sbjct: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
Query: 294 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 353
QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL
Sbjct: 269 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 328
Query: 354 IEFATVNYFTKRSWAWEGKK-VPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-DT 411
IEFATVNYFTKR +AW+GK VPE K K P K + T+ T+Y NLA+ D
Sbjct: 329 IEFATVNYFTKRGYAWDGKSVVPE----KPKKVKDPLIKKNNTYAPTATSYTPNLARGDP 384
Query: 412 EFSTISKGAAPSASSTPTIIASPKATYVQDSPTE-TKTYNSVSKVDKISRIIFPVLFAIF 470
+TI+K A PK + P E KT+NSVSK+D++SRI FP+LF IF
Sbjct: 385 GLATIAKSAT----------IEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIF 434
Query: 471 NLVYWATYVNRESAIK 486
NLVYWATY+NRE +K
Sbjct: 435 NLVYWATYLNREPQLK 450
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 639 bits (1648), Expect = 0.0
Identities = 324/436 (74%), Positives = 357/436 (81%), Gaps = 17/436 (3%)
Query: 54 PDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYT 113
P + D+ DN T+FTRILDRLLDGYDNRLRPGLG+ VTEVKTDI+VTSFGPVSD DMEYT
Sbjct: 29 PSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYT 88
Query: 114 IDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRL 173
IDVFFRQ+W DERLKF GPM +L LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
Query: 174 VDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEV 233
++GTLLYTMRLT+ AECPMHLEDFPMD HACPLKFGSYAYT AEVVY WT +SV V
Sbjct: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
Query: 234 AQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 293
A+DGSRLNQYDLLG V + I++SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS
Sbjct: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
Query: 294 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 353
QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL
Sbjct: 269 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 328
Query: 354 IEFATVNYFTKRSWAWEGKK-VPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-DT 411
IEFATVNYFTKR +AW+GK VPE K K P K + T+ T+Y NLA+ D
Sbjct: 329 IEFATVNYFTKRGYAWDGKSVVPE----KPKKVKDPLIKKNNTYAPTATSYTPNLARGDP 384
Query: 412 EFSTISKGAAPSASSTPTIIASPKATYVQDSPTE-TKTYNSVSKVDKISRIIFPVLFAIF 470
+TI+K A PK + P E KT+NSVSK+D++SRI FP+LF IF
Sbjct: 385 GLATIAKSAT----------IEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIF 434
Query: 471 NLVYWATYVNRESAIK 486
NLVYWATY+NRE +K
Sbjct: 435 NLVYWATYLNREPQLK 450
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 639 bits (1648), Expect = 0.0
Identities = 324/436 (74%), Positives = 357/436 (81%), Gaps = 17/436 (3%)
Query: 54 PDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYT 113
P + D+ DN T+FTRILDRLLDGYDNRLRPGLG+ VTEVKTDI+VTSFGPVSD DMEYT
Sbjct: 29 PSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYT 88
Query: 114 IDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRL 173
IDVFFRQ+W DERLKF GPM +L LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
Query: 174 VDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEV 233
++GTLLYTMRLT+ AECPMHLEDFPMD HACPLKFGSYAYT AEVVY WT +SV V
Sbjct: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
Query: 234 AQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 293
A+DGSRLNQYDLLG V + I++SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS
Sbjct: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
Query: 294 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 353
QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL
Sbjct: 269 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 328
Query: 354 IEFATVNYFTKRSWAWEGKK-VPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-DT 411
IEFATVNYFTKR +AW+GK VPE K K P K + T+ T+Y NLA+ D
Sbjct: 329 IEFATVNYFTKRGYAWDGKSVVPE----KPKKVKDPLIKKNNTYAPTATSYTPNLARGDP 384
Query: 412 EFSTISKGAAPSASSTPTIIASPKATYVQDSPTE-TKTYNSVSKVDKISRIIFPVLFAIF 470
+TI+K A PK + P E KT+NSVSK+D++SRI FP+LF IF
Sbjct: 385 GLATIAKSAT----------IEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIF 434
Query: 471 NLVYWATYVNRESAIK 486
NLVYWATY+NRE +K
Sbjct: 435 NLVYWATYLNREPQLK 450
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 639 bits (1648), Expect = 0.0
Identities = 324/436 (74%), Positives = 357/436 (81%), Gaps = 17/436 (3%)
Query: 54 PDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYT 113
P + D+ DN T+FTRILDRLLDGYDNRLRPGLG+ VTEVKTDI+VTSFGPVSD DMEYT
Sbjct: 29 PSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYT 88
Query: 114 IDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRL 173
IDVFFRQ+W DERLKF GPM +L LNNL+ASKIWTPDTFFHNGKKSVAHNMT PNKLLR+
Sbjct: 89 IDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRI 148
Query: 174 VDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEV 233
++GTLLYTMRLT+ AECPMHLEDFPMD HACPLKFGSYAYT AEVVY WT +SV V
Sbjct: 149 TEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVV 208
Query: 234 AQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 293
A+DGSRLNQYDLLG V + I++SSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS
Sbjct: 209 AEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILS 268
Query: 294 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 353
QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL
Sbjct: 269 QVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSAL 328
Query: 354 IEFATVNYFTKRSWAWEGKK-VPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-DT 411
IEFATVNYFTKR +AW+GK VPE K K P K + T+ T+Y NLA+ D
Sbjct: 329 IEFATVNYFTKRGYAWDGKSVVPE----KPKKVKDPLIKKNNTYAPTATSYTPNLARGDP 384
Query: 412 EFSTISKGAAPSASSTPTIIASPKATYVQDSPTE-TKTYNSVSKVDKISRIIFPVLFAIF 470
+TI+K A PK + P E KT+NSVSK+D++SRI FP+LF IF
Sbjct: 385 GLATIAKSAT----------IEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIF 434
Query: 471 NLVYWATYVNRESAIK 486
NLVYWATY+NRE +K
Sbjct: 435 NLVYWATYLNREPQLK 450
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 517 bits (1331), Expect = e-146
Identities = 264/428 (61%), Positives = 321/428 (75%), Gaps = 27/428 (6%)
Query: 68 TRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
+RILD LL+GYDNRLRPG G AVTEVKTDIYVTSFGPVSD +MEYT+DVFFRQTW DERL
Sbjct: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
Query: 128 KFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTI 187
KF GP +IL LNNL+ SKIWTPDTFF NGKKS+AHNMTTPNKL R++ NGT+LYTMRLTI
Sbjct: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
Query: 188 HAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLG 247
+A+CPM L +FPMD HACPLKFGSYAY +E++Y+W G SVEV ++ S L QYDL+G
Sbjct: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
Query: 248 HVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 307
V +E I+S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
Query: 308 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSW 367
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNL-- 330
Query: 368 AWEGKKVPEALEMKKKTP-AAPAKKTSTTFNIVGTTYPIN----LAKDTEF---STISKG 419
+ + K+K AAP T I T P+ L D+++ I+
Sbjct: 331 --------QTQKAKRKAQFAAP-----PTVTISKATEPLEAEIVLHPDSKYHLKKRITSL 377
Query: 420 AAPSASSTPTIIASPKATYVQDSPTE----TKTYNSVSKVDKISRIIFPVLFAIFNLVYW 475
+ P SS+ +A +Q +P + + SK+D+ SRI+FPV FA FNLVYW
Sbjct: 378 SLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYW 437
Query: 476 ATYVNRES 483
Y+++++
Sbjct: 438 VVYLSKDT 445
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 510 bits (1313), Expect = e-144
Identities = 273/503 (54%), Positives = 334/503 (66%), Gaps = 84/503 (16%)
Query: 67 FTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDER 126
FTRILD LLDGYDNRLRPG G VTEVKTDIYVTSFGPVSD +MEYT+DVFFRQTW D+R
Sbjct: 48 FTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKR 107
Query: 127 LKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
LK+DGP++IL LNN++ +K+WTPDTFF NGKKSV+HNMT PNKL R++ NGT+LYTMRLT
Sbjct: 108 LKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLT 167
Query: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
I AECPM L DFPMD HACPLKFGSYAY +E++Y+WT G KSVEV ++ S L QYDL+
Sbjct: 168 ISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLI 227
Query: 247 GHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 306
G V +E I+S TGEY+VMT +FHL+RK+GYF+IQTY+PCIMTVILSQVSFW+N+ESVPA
Sbjct: 228 GQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPA 287
Query: 307 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT--- 363
RTVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 288 RTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQ 347
Query: 364 ----KRSWAWEGKKVPEA------------------LEMKKKTPAAP------------- 388
KR + ++VP A L M+K+T A
Sbjct: 348 MEKAKRKTSKPPQEVPAAPVQREKHPEAPLQNTNANLNMRKRTNALVHSESDVGNRTEVG 407
Query: 389 --AKKTSTTFN----------IVGTTYPINLAKDTEFSTISKGAAPSASSTP-------- 428
+ K+ST + + P + A E + ++ A PSAS T
Sbjct: 408 NHSSKSSTVVQESSKGTPRSYLASSPNPFSRANAAETISAAR-ALPSASPTSIRTGYMPR 466
Query: 429 -------------------------TIIASPKATYVQDSPTETKTYNSVSKVDKISRIIF 463
TI A+ K + + + SK+DK +RI+F
Sbjct: 467 KASVGSASTRHVFGSRLQRIKTTVNTIGATGKLSATPPPSAPPPSGSGTSKIDKYARILF 526
Query: 464 PVLFAIFNLVYWATYVNRESAIK 486
PV F FN+VYW Y+++++ K
Sbjct: 527 PVTFGAFNMVYWVVYLSKDTMEK 549
>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
precursor [Homo sapiens]
Length = 467
Score = 384 bits (987), Expect = e-107
Identities = 207/467 (44%), Positives = 290/467 (62%), Gaps = 31/467 (6%)
Query: 16 ILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLL 75
IL L+++ PG T Q E D+ L+PK +P+ T IL+ LL
Sbjct: 27 ILLLLSLYPGFTSQKSDDDYE--DYASNKTWVLTPK----VPEGDV------TVILNNLL 74
Query: 76 DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKI 135
+GYDN+LRP +G T + TD+YV S GPV+ +MEYTID+FF QTW+D RLKF+ +K+
Sbjct: 75 EGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKV 134
Query: 136 LPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHL 195
L LN+ + KIW PDTFF N KK+ AH +TTPN++LR+ ++G +LYT+RLTI AEC + L
Sbjct: 135 LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQL 194
Query: 196 EDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGS-RLNQYDLLGHVVGTEI 254
+FPMD H+CPL+F SY Y E+VY W K SVEV S RL Q+ +G TE+
Sbjct: 195 HNFPMDEHSCPLEFSSYGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFVGLRNTTEV 251
Query: 255 IRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTT 314
+++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TT
Sbjct: 252 VKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITT 311
Query: 315 VLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKV 374
VLTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF +K
Sbjct: 312 VLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV------SNRKP 365
Query: 375 PEALEMKKKTPA--APAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASSTPTIIA 432
+ + KKK PA + S T + T+ +D E+ AS
Sbjct: 366 SKDKDKKKKNPAPTIDIRPRSATIQMNNATH--LQERDEEYGYECLDGKDCASFFCCFED 423
Query: 433 SPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYV 479
+ + + ++K+D +RI FP F +FNLVYW +Y+
Sbjct: 424 CRTGAW-----RHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
precursor [Homo sapiens]
Length = 475
Score = 383 bits (984), Expect = e-106
Identities = 209/469 (44%), Positives = 290/469 (61%), Gaps = 27/469 (5%)
Query: 16 ILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLL 75
IL L+++ PG T Q E D+ L+PK +P+ T IL+ LL
Sbjct: 27 ILLLLSLYPGFTSQKSDDDYE--DYASNKTWVLTPK----VPEGDV------TVILNNLL 74
Query: 76 DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKI 135
+GYDN+LRP +G T + TD+YV S GPV+ +MEYTID+FF QTW+D RLKF+ +K+
Sbjct: 75 EGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKV 134
Query: 136 LPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHL 195
L LN+ + KIW PDTFF N KK+ AH +TTPN++LR+ ++G +LYT+RLTI AEC + L
Sbjct: 135 LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQL 194
Query: 196 EDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGS-RLNQYDLLGHVVGTEI 254
+FPMD H+CPL+F SY Y E+VY W K SVEV S RL Q+ +G TE+
Sbjct: 195 HNFPMDEHSCPLEFSSYGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFVGLRNTTEV 251
Query: 255 IRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTT 314
+++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TT
Sbjct: 252 VKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITT 311
Query: 315 VLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---KRSWAWEG 371
VLTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF K S +
Sbjct: 312 VLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDK 371
Query: 372 KKVPEALEM-KKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASSTPTI 430
KK L M K P + S T + T+ +D E+ AS
Sbjct: 372 KKKNPLLRMFSFKAPTIDIRPRSATIQMNNATH--LQERDEEYGYECLDGKDCASFFCCF 429
Query: 431 IASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYV 479
+ + + ++K+D +RI FP F +FNLVYW +Y+
Sbjct: 430 EDCRTGAW-----RHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 473
>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
[Homo sapiens]
Length = 465
Score = 379 bits (974), Expect = e-105
Identities = 196/413 (47%), Positives = 269/413 (65%), Gaps = 15/413 (3%)
Query: 68 TRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
T+IL+ LL GYDN+LRP +G T ++TD+YV S GPV +MEYTID+ F QTW D RL
Sbjct: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
Query: 128 KFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTI 187
KF+ MK+L LN+ + KIW PDTFF N +KS AH +TTPN+LLR+ ++G +LYT+RLTI
Sbjct: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
Query: 188 HAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGS-RLNQYDLL 246
+AEC + L +FPMD H+CPL+F SY Y E+ Y W K SVEVA RL Q+ +
Sbjct: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKW---KKPSVEVADPKYWRLYQFAFV 241
Query: 247 GHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 306
G TEI + +G+YV+MT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPA
Sbjct: 242 GLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPA 301
Query: 307 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRS 366
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 302 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQ 361
Query: 367 WAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASS 426
+GK + ++K K P +T + I++ ++ ++ AS
Sbjct: 362 ---KGKTATKDRKLKNKASMTPGLHPGSTLIPMNN---ISVPQEDDYGYQCLEGKDCASF 415
Query: 427 TPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYV 479
++ E + + ++K+D SRI FP FA+FNLVYW Y+
Sbjct: 416 FCCFEDCRTGSW-----REGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
precursor [Homo sapiens]
Length = 515
Score = 362 bits (929), Expect = e-100
Identities = 208/509 (40%), Positives = 291/509 (57%), Gaps = 67/509 (13%)
Query: 16 ILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLL 75
IL L+++ PG T Q E D+ L+PK +P+ T IL+ LL
Sbjct: 27 ILLLLSLYPGFTSQKSDDDYE--DYASNKTWVLTPK----VPEGDV------TVILNNLL 74
Query: 76 DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKI 135
+GYDN+LRP +G T + TD+YV S GPV+ +MEYTID+FF QTW+D RLKF+ +K+
Sbjct: 75 EGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKV 134
Query: 136 LPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHL 195
L LN+ + KIW PDTFF N KK+ AH +TTPN++LR+ ++G +LYT+RLTI AEC + L
Sbjct: 135 LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQL 194
Query: 196 EDFPMDVHACPLKFGSYA----------------------------------------YT 215
+FPMD H+CPL+F S++ Y
Sbjct: 195 HNFPMDEHSCPLEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPPTLASRVAGISDGYP 254
Query: 216 TAEVVYSWTLGKNKSVEVAQDGS-RLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRK 274
E+VY W K SVEV S RL Q+ +G TE++++++G+YVVM+ +F L R+
Sbjct: 255 REEIVYQW---KRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRR 311
Query: 275 IGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAY 334
+GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTVLTMTTLS AR SLPKV+Y
Sbjct: 312 MGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSY 371
Query: 335 ATAMDWFIAVCYAFVFSALIEFATVNYFT---KRSWAWEGKKVPEALEM-KKKTPAAPAK 390
TAMD F++VC+ FVFSAL+E+ T++YF K S + KK L M K P +
Sbjct: 372 VTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRMFSFKAPTIDIR 431
Query: 391 KTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASSTPTIIASPKATYVQDSPTETKTYN 450
S T + T+ +D E+ AS + + +
Sbjct: 432 PRSATIQMNNATH--LQERDEEYGYECLDGKDCASFFCCFEDCRTGAW-----RHGRIHI 484
Query: 451 SVSKVDKISRIIFPVLFAIFNLVYWATYV 479
++K+D +RI FP F +FNLVYW +Y+
Sbjct: 485 RIAKMDSYARIFFPTAFCLFNLVYWVSYL 513
>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
Length = 467
Score = 355 bits (910), Expect = 7e-98
Identities = 189/425 (44%), Positives = 261/425 (61%), Gaps = 14/425 (3%)
Query: 65 TIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHD 124
T T IL++LL YD +LRP +G T + DIYV S GPVS +MEY ID+FF QTW D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 125 ERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMR 184
RL+F+ MKIL LN+ + IW PDT F N K + AH +TTPN+LLR+ ++G +LYT+R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 185 LTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGS-RLNQY 243
LTI+AEC + L +FPMD H+CPL F SY Y E++Y W + SVE A S RL Q+
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRW---RKNSVEAADQKSWRLYQF 221
Query: 244 DLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRES 303
D +G TEI+ +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+ +++
Sbjct: 222 DFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDA 281
Query: 304 VPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT 363
PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+NY++
Sbjct: 282 TPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYS 341
Query: 364 KRSWAWEGKKVPEAL--EMKKKTPAAPAKKTSTTFNIVGTTYP----INLAKDT---EFS 414
KK L + + P + + + ++++ P I L EF
Sbjct: 342 SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFE 401
Query: 415 TISKGAAPSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVY 474
+ + S + + + + ++D SR+ FP F +FNLVY
Sbjct: 402 DTCVYECLDGKDCQSFFCCYEEC-KSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVY 460
Query: 475 WATYV 479
W Y+
Sbjct: 461 WVGYL 465
>gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon
precursor [Homo sapiens]
Length = 506
Score = 304 bits (779), Expect = 1e-82
Identities = 163/437 (37%), Positives = 252/437 (57%), Gaps = 27/437 (6%)
Query: 68 TRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
+RIL+ +L YD++LRPG+G+ T V +I V S GP+S DMEYTID+ F QTW+DERL
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERL 131
Query: 128 KFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTI 187
++ + L LN + S++W PDTFF N K++ H +T PN+++R+ +G +LYT+R+TI
Sbjct: 132 CYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTI 191
Query: 188 HAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGS-RLNQYDLL 246
A C +H+ FPMD H+CPL F S++Y E++Y W +N +E+ + S +L Q+D
Sbjct: 192 DAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKW---ENFKLEINEKNSWKLFQFDFT 248
Query: 247 GHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 306
G TEII + G+++VMT F++ R+ GY Q Y+P +T +LS VSFW+ ES PA
Sbjct: 249 GVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPA 308
Query: 307 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT-KR 365
RT G+T+VLTMTTL +R + P+V+Y TA+D++IA+C+ F F AL+EFA +N+ +
Sbjct: 309 RTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIYNQ 368
Query: 366 SWAWEGKKV------PEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKG 419
+ A K+ A + A A++ F T + ++ + +
Sbjct: 369 TKAHASPKLRHPRINSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEERPSCSAQQP 428
Query: 420 AAPSASSTPTIIASP----------KATYVQDSPTETKTYNS------VSKVDKISRIIF 463
+P + P + S K + E T+ V ++D SR++F
Sbjct: 429 PSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYRLDNYSRVVF 488
Query: 464 PVLFAIFNLVYWATYVN 480
PV F FN++YW +N
Sbjct: 489 PVTFFFFNVLYWLVCLN 505
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 276 bits (707), Expect = 2e-74
Identities = 159/446 (35%), Positives = 239/446 (53%), Gaps = 33/446 (7%)
Query: 63 NITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTW 122
N++ +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W
Sbjct: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92
Query: 123 HDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYT 182
D+RL + G L L+N +A ++W PDT+F N KKS H +T N+++RL +GT+LY
Sbjct: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152
Query: 183 MRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQ 242
+R+T A C M L +P+D C L+ SY YTT ++ + W G +K+V + L Q
Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWR-GGDKAV-TGVERIELPQ 210
Query: 243 YDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 302
+ ++ H + + + +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N +
Sbjct: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270
Query: 303 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYF 362
+ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY
Sbjct: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330
Query: 363 TKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAP 422
KK+ E K +K S + G +L E + +S G
Sbjct: 331 FFGRGPQRQKKLAEKTAKAKND---RSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGD 387
Query: 423 SASSTPTIIASPKATYVQDSPTE-------------TKTY---------------NSVSK 454
+ +S + S Q P E KT+ V+
Sbjct: 388 TRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNA 447
Query: 455 VDKISRIIFPVLFAIFNLVYWATYVN 480
+D+ SRI+FP F++FNLVYW YVN
Sbjct: 448 IDRWSRIVFPFTFSLFNLVYWLYYVN 473
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 276 bits (707), Expect = 2e-74
Identities = 159/446 (35%), Positives = 239/446 (53%), Gaps = 33/446 (7%)
Query: 63 NITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTW 122
N++ +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W
Sbjct: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92
Query: 123 HDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYT 182
D+RL + G L L+N +A ++W PDT+F N KKS H +T N+++RL +GT+LY
Sbjct: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152
Query: 183 MRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQ 242
+R+T A C M L +P+D C L+ SY YTT ++ + W G +K+V + L Q
Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWR-GGDKAV-TGVERIELPQ 210
Query: 243 YDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 302
+ ++ H + + + +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N +
Sbjct: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270
Query: 303 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYF 362
+ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY
Sbjct: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330
Query: 363 TKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAP 422
KK+ E K +K S + G +L E + +S G
Sbjct: 331 FFGRGPQRQKKLAEKTAKAKND---RSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGD 387
Query: 423 SASSTPTIIASPKATYVQDSPTE-------------TKTY---------------NSVSK 454
+ +S + S Q P E KT+ V+
Sbjct: 388 TRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNA 447
Query: 455 VDKISRIIFPVLFAIFNLVYWATYVN 480
+D+ SRI+FP F++FNLVYW YVN
Sbjct: 448 IDRWSRIVFPFTFSLFNLVYWLYYVN 473
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 276 bits (705), Expect = 4e-74
Identities = 158/445 (35%), Positives = 239/445 (53%), Gaps = 29/445 (6%)
Query: 63 NITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTW 122
N+++ +DRLL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W
Sbjct: 32 NMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAW 91
Query: 123 HDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYT 182
D+RL ++ L L+N +A ++W PDT+F N KKS H +T N+++RL +GT+LY
Sbjct: 92 RDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 151
Query: 183 MRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQ 242
+R+T A C M L +P+D C L+ SY YTT ++ + W N V + L Q
Sbjct: 152 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTK--IELPQ 209
Query: 243 YDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 302
+ ++ + + T+ + STG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N +
Sbjct: 210 FSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYD 269
Query: 303 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 361
+ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY
Sbjct: 270 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
Query: 362 FTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPIN--------------- 406
F R + K +A + K NI+ +T I
Sbjct: 330 FFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDP 389
Query: 407 ----LAKDTEFSTISKGAAPSASSTPTII---ASPKATYVQDSPTETK----TYNSVSKV 455
LA D K P S + + K + ++ ++ K V+ +
Sbjct: 390 RSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAI 449
Query: 456 DKISRIIFPVLFAIFNLVYWATYVN 480
D+ SRI FPV+F+ FN+VYW YVN
Sbjct: 450 DRWSRIFFPVVFSFFNIVYWLYYVN 474
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 271 bits (692), Expect = 1e-72
Identities = 159/419 (37%), Positives = 238/419 (56%), Gaps = 23/419 (5%)
Query: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
LD+L+ GYD R+RP V +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
Query: 128 KFDG-PMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
++ P L L+ + IW PD FF N K + H +TT NKLLR+ NG +LY++R+T
Sbjct: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
Query: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
+ CPM L++FPMDV C ++ S+ YT ++++ W + +V+VA DG L Q+ L
Sbjct: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ--EQGAVQVA-DGLTLPQFILK 218
Query: 247 GHVVGTEIIRS-STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 305
+ +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ P
Sbjct: 219 EEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAP 278
Query: 306 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 279 ARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR- 337
Query: 366 SWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSAS 425
+ K++ ++ A + F+ G AKD KGA S +
Sbjct: 338 ----QHKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKD---GISVKGANNSNT 390
Query: 426 STPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATY--VNRE 482
+ P P A K+DKISRI FP+ F IFN+ YW Y V RE
Sbjct: 391 TNP-----PPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRRE 444
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 271 bits (692), Expect = 1e-72
Identities = 160/456 (35%), Positives = 242/456 (53%), Gaps = 52/456 (11%)
Query: 63 NITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTW 122
N++ +DRLL GYD RLRP G +V I V S VS+ +M+YT+ ++F+Q+W
Sbjct: 33 NMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSW 92
Query: 123 HDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYT 182
D+RL + G L L+N +A ++W PDT+F N KKS H +T N+++RL +GT+LY
Sbjct: 93 KDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152
Query: 183 MRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQ 242
+R+T A C M L +P+D C L+ SY YTT ++ + W G+ V + L Q
Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGV--NKIELPQ 210
Query: 243 YDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 302
+ ++ + + ++ + +TG Y ++ F LKR IGYF++QTY+P + ILS VSFW+N +
Sbjct: 211 FSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYD 270
Query: 303 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYF 362
+ AR G+TTVLTMTT+S R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY
Sbjct: 271 ASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYI 330
Query: 363 TKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAP 422
+ GK P+ K+ +A +K N V N+ ST+
Sbjct: 331 ------FFGKG-PQKKGASKQDQSA-NEKNKLEMNKVQVDAHGNIL----LSTLEIRNET 378
Query: 423 SASSTPTIIASPKAT-YVQDSPT------------------------------------- 444
S S T ++ PKAT Y DS +
Sbjct: 379 SGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKV 438
Query: 445 ETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN 480
+ V+ +DK SR+ FP+ F++FN+VYW YV+
Sbjct: 439 KIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 474
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 270 bits (691), Expect = 2e-72
Identities = 154/413 (37%), Positives = 235/413 (56%), Gaps = 24/413 (5%)
Query: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
LD+L+ GYD R+RP V +I++ SFG V++T M+Y +++F RQ W+D RL
Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRL 107
Query: 128 KF-DGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
+ + P L L+ + IW PD FF N K + H++TT NKLLR+ NG +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
Query: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
+ CPM L++FPMDV C ++ S+ YT ++++ W + V+VA+ G L Q+ L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVAE-GLTLPQFILK 224
Query: 247 GHV-VGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 305
+G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
Query: 306 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR- 343
Query: 366 SWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSAS 425
+ K+ +K+ + FN G Y + + G A A+
Sbjct: 344 ----QHKEFLRLRRRQKRQNKEEDVTRESRFNFSG--YGMG-----HCLQVKDGTAVKAT 392
Query: 426 STPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATY 478
+ PK + K + ++D ISR FP+ F IFN+ YW TY
Sbjct: 393 PANPLPQPPK----DGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 270 bits (691), Expect = 2e-72
Identities = 159/416 (38%), Positives = 235/416 (56%), Gaps = 34/416 (8%)
Query: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
LD+L+ GYD R+RP V +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
Query: 128 KF-DGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
+ + P L L+ + IW PD FF N K + H +TT NKLLR+ NG +LY++RLT
Sbjct: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
Query: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
+ CPM L++FPMDV C ++ S+ YT ++++ W V+VA+ G L Q+ LL
Sbjct: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ--DEAPVQVAE-GLTLPQF-LL 222
Query: 247 GHVVGTEIIRS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 304
+TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
Query: 305 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 364
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
Query: 365 RSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSA 424
+ K K+K +++ +F G P AKD G P
Sbjct: 343 Q------HKELLRFRRKRKNKDDEVRESRFSFTAYGMG-PCLQAKD--------GMTPKG 387
Query: 425 SSTPTIIASPKATYVQDSPTETKT--YNSVSKVDKISRIIFPVLFAIFNLVYWATY 478
+ P + PK SP E + + K+D ISR FP+ F IFN+ YW Y
Sbjct: 388 PNHP-VQVMPK------SPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 270 bits (691), Expect = 2e-72
Identities = 154/413 (37%), Positives = 235/413 (56%), Gaps = 24/413 (5%)
Query: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
LD+L+ GYD R+RP V +I++ SFG V++T M+Y +++F RQ W+D RL
Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRL 107
Query: 128 KF-DGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
+ + P L L+ + IW PD FF N K + H++TT NKLLR+ NG +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
Query: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
+ CPM L++FPMDV C ++ S+ YT ++++ W + V+VA+ G L Q+ L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVAE-GLTLPQFILK 224
Query: 247 GHV-VGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 305
+G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
Query: 306 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR- 343
Query: 366 SWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSAS 425
+ K+ +K+ + FN G Y + + G A A+
Sbjct: 344 ----QHKEFLRLRRRQKRQNKEEDVTRESRFNFSG--YGMG-----HCLQVKDGTAVKAT 392
Query: 426 STPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATY 478
+ PK + K + ++D ISR FP+ F IFN+ YW TY
Sbjct: 393 PANPLPQPPK----DGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 270 bits (690), Expect = 2e-72
Identities = 153/413 (37%), Positives = 235/413 (56%), Gaps = 24/413 (5%)
Query: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
LD+L+ GYD R+RP V +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
Query: 128 KF-DGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
+ + P L L+ + IW PD FF N K + H++TT NKLLR+ NG +LY++RLT
Sbjct: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
Query: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
+ CPM L++FPMDV C ++ S+ YT ++++ W + V+VA+ G L Q+ L
Sbjct: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVAE-GLTLPQFILK 224
Query: 247 GHV-VGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 305
+G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
Query: 306 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR- 343
Query: 366 SWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSAS 425
+ K+ +K+ + FN G Y + + G A A+
Sbjct: 344 ----QHKEFLRLRRRQKRQNKEEDVTRESRFNFSG--YGMG-----HCLQVKDGTAVKAT 392
Query: 426 STPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATY 478
+ PK + K + ++D ISR FP+ F IFN+ YW TY
Sbjct: 393 PANPLPQPPK----DGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 269 bits (688), Expect = 4e-72
Identities = 161/422 (38%), Positives = 236/422 (55%), Gaps = 21/422 (4%)
Query: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
LD+L+ GYD R+RP V +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
Query: 128 KFDG-PMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
++ P L L+ + IW PD FF N K + H +TT NKLLR+ NG +LY++R+T
Sbjct: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
Query: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
+ CPM L++FPMDV C ++ S+ YT ++++ W + +V+VA DG L Q+ L
Sbjct: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ--EQGAVQVA-DGLTLPQFILK 218
Query: 247 GHVVGTEIIRS-STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 305
+ +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ P
Sbjct: 219 EEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAP 278
Query: 306 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT-- 363
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 279 ARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ 338
Query: 364 -KRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAP 422
K + K+ M A + F+ G AKD KGA
Sbjct: 339 HKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKD---GISVKGANN 395
Query: 423 SASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATY--VN 480
S ++ P P A K+DKISRI FP+ F IFN+ YW Y V
Sbjct: 396 SNTTNP-----PPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVR 450
Query: 481 RE 482
RE
Sbjct: 451 RE 452
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 268 bits (685), Expect = 8e-72
Identities = 156/419 (37%), Positives = 238/419 (56%), Gaps = 25/419 (5%)
Query: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
LD+L+ GYD R+RP V +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
Query: 128 KF-DGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
+ + P L L+ + IW PD FF N K + H +TT NKLLR+ NG +LY++RLT
Sbjct: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
Query: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
+ CPM L++FPMDV C ++ S+ YT ++++ W V+VA+ G L Q+ LL
Sbjct: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ--DEAPVQVAE-GLTLPQF-LL 222
Query: 247 GHVVGTEIIRS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 304
+TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
Query: 305 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 364
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
Query: 365 RSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSA 424
+ K++ +K A A + F+ + + +++ FS + G P
Sbjct: 343 -----QHKELLRFRRKRKNKTEAFALEKFYRFSDMD-----DEVRESRFSFTAYGMGPCL 392
Query: 425 SSTPTIIASPKATYVQ---DSPTETKT--YNSVSKVDKISRIIFPVLFAIFNLVYWATY 478
+ + VQ SP E + + K+D ISR FP+ F IFN+ YW Y
Sbjct: 393 QAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,557,676
Number of Sequences: 37866
Number of extensions: 749674
Number of successful extensions: 2306
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 2036
Number of HSP's gapped (non-prelim): 237
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.