Guide to the Human Genome
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Search of human proteins with 4557489

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557489 cone-rod homeobox protein [Homo sapiens]
         (299 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557489 cone-rod homeobox protein [Homo sapiens]                   612   e-176
gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]         266   2e-71
gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]         259   3e-69
gi|20070107 orthodenticle homeobox 1 [Homo sapiens]                   224   9e-59
gi|61969666 arginine-fifty homeobox [Homo sapiens]                    136   3e-32
gi|12707580 paired-like homeobox 2b [Homo sapiens]                    111   9e-25
gi|46249382 paired-like homeobox 2a [Homo sapiens]                    110   2e-24
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom...   107   1e-23
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom...   103   2e-22
gi|4826912 paired-like homeodomain 3 [Homo sapiens]                   100   1e-21
gi|24497589 aristaless related homeobox [Homo sapiens]                100   2e-21
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...    97   2e-20
gi|122937484 dorsal root ganglia homeobox [Homo sapiens]               97   2e-20
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                       96   3e-20
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                       96   3e-20
gi|207029223 paired box 7 isoform 3 [Homo sapiens]                     96   3e-20
gi|189083681 paired box gene 6 isoform a [Homo sapiens]                96   3e-20
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                  96   3e-20
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                  96   3e-20
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    96   4e-20
gi|113204604 aristaless-like homeobox 3 [Homo sapiens]                 94   1e-19
gi|7706659 paired related homeobox 2 [Homo sapiens]                    94   2e-19
gi|55743092 aristaless-like homeobox 4 [Homo sapiens]                  92   4e-19
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                   92   7e-19
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                 91   1e-18
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                  91   1e-18
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                  91   1e-18
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                  88   1e-17
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                  88   1e-17
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]      88   1e-17

>gi|4557489 cone-rod homeobox protein [Homo sapiens]
          Length = 299

 Score =  612 bits (1579), Expect = e-176
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK 60
           MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK
Sbjct: 1   MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK 60

Query: 61  TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK 120
           TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK
Sbjct: 61  TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK 120

Query: 121 AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLV 180
           AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLV
Sbjct: 121 AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLV 180

Query: 181 ASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGP 240
           ASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGP
Sbjct: 181 ASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGP 240

Query: 241 SVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL 299
           SVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL
Sbjct: 241 SVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL 299


>gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
          Length = 289

 Score =  266 bits (680), Expect = 2e-71
 Identities = 158/309 (51%), Positives = 197/309 (63%), Gaps = 30/309 (9%)

Query: 1   MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK 60
           MM+Y+   P Y+VN L+L+   +DL+H +V YP+ PRKQRRERTTFTR+QL+ LEALFAK
Sbjct: 1   MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAK 59

Query: 61  TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK 120
           T+YPD++ REEVALKINLPESRVQVWFKNRRAKCRQQ     QQQQ  GGQ K RPAK+K
Sbjct: 60  TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQNKVRPAKKK 114

Query: 121 AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLV 180
              +   S++      G S  ++PP      +  ++ A VSIWSPAS SPL +      +
Sbjct: 115 TSPAREVSSE-----SGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDP-----L 164

Query: 181 ASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLGGP--ALSP 236
           ++  S     Y MTY  AS +      Y   +SYF G+D   YL+PM  QL GP   LSP
Sbjct: 165 STSSSCMQRSYPMTYTQASGY---SQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSP 221

Query: 237 LSGPSVGPSLAQSPTSLSGQSYGA-----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQ 291
           +   +V   L QSP SLS Q YGA      S  D L++KD T +WK  +N  D LDYKDQ
Sbjct: 222 MGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFN-ADCLDYKDQ 280

Query: 292 -SAWKFQIL 299
            S+WKFQ+L
Sbjct: 281 TSSWKFQVL 289


>gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]
          Length = 297

 Score =  259 bits (661), Expect = 3e-69
 Identities = 158/317 (49%), Positives = 197/317 (62%), Gaps = 38/317 (11%)

Query: 1   MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYP--------SAPRKQRRERTTFTRSQLE 52
           MM+Y+   P Y+VN L+L+   +DL+H +V YP        + PRKQRRERTTFTR+QL+
Sbjct: 1   MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLD 59

Query: 53  ELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQA 112
            LEALFAKT+YPD++ REEVALKINLPESRVQVWFKNRRAKCRQQ     QQQQ  GGQ 
Sbjct: 60  VLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQN 114

Query: 113 KARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLP 172
           K RPAK+K   +   S++      G S  ++PP      +  ++ A VSIWSPAS SPL 
Sbjct: 115 KVRPAKKKTSPAREVSSE-----SGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLS 169

Query: 173 EAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLG 230
           +      +++  S     Y MTY  AS +      Y   +SYF G+D   YL+PM  QL 
Sbjct: 170 DP-----LSTSSSCMQRSYPMTYTQASGY---SQGYAGSTSYFGGMDCGSYLTPMHHQLP 221

Query: 231 GP--ALSPLSGPSVGPSLAQSPTSLSGQSYGA-----YSPVDSLEFKDPTGTWKFTYNPM 283
           GP   LSP+   +V   L QSP SLS Q YGA      S  D L++KD T +WK  +N  
Sbjct: 222 GPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFN-A 280

Query: 284 DPLDYKDQ-SAWKFQIL 299
           D LDYKDQ S+WKFQ+L
Sbjct: 281 DCLDYKDQTSSWKFQVL 297


>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
          Length = 354

 Score =  224 bits (570), Expect = 9e-59
 Identities = 152/366 (41%), Positives = 198/366 (54%), Gaps = 79/366 (21%)

Query: 1   MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK 60
           MM+Y+   P Y +N L L+GP++DL+H +V YP+ PRKQRRERTTFTRSQL+ LEALFAK
Sbjct: 1   MMSYLKQPP-YGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAK 59

Query: 61  TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK 120
           T+YPD++ REEVALKINLPESRVQVWFKNRRAKCRQQ+Q         G   K+RPAK+K
Sbjct: 60  TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQS--------GSGTKSRPAKKK 111

Query: 121 AG--------------TSPRPSTDVCPDPLGISDSYSP---PLPGPSGSPTTAVATV--- 160
           +               T P  S+         S S +P      G  G+P  A +++   
Sbjct: 112 SSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTP 171

Query: 161 ---SIWSPASESP--------LPEAQRA--------GLVASGPSLTSAPYAMTYAPASAF 201
              SIWSPAS SP        +PE   A          VA+G +  +A Y M+Y    ++
Sbjct: 172 AASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSY 231

Query: 202 CSSPSAYGSP-SSYFSGLD--PYLSPM-----VPQLGGPALSPLSGPSVGPSLAQSPTSL 253
                 Y +P SSYF G+D   YL+PM       QL   A S ++G       A  P S 
Sbjct: 232 ---GQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQ 288

Query: 254 SG-----------QSYG----AYSPVDSLEFKDP-----TGTWKFTYNPMDPLDYKDQSA 293
           S            Q YG    A++  D L++K+P     +  WK  +N  D LDYKDQ++
Sbjct: 289 SSGHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQAS 348

Query: 294 WKFQIL 299
           W+FQ+L
Sbjct: 349 WRFQVL 354


>gi|61969666 arginine-fifty homeobox [Homo sapiens]
          Length = 315

 Score =  136 bits (342), Expect = 3e-32
 Identities = 93/239 (38%), Positives = 135/239 (56%), Gaps = 9/239 (3%)

Query: 34  SAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAK 93
           +A R++ +ERT+FT  Q EELEALF++T +PD   +E++AL+++LPES V+VWF+NRR K
Sbjct: 73  TAIRRRHKERTSFTHQQYEELEALFSQTMFPDRNLQEKLALRLDLPESTVKVWFRNRRFK 132

Query: 94  CRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSP 153
            ++Q+QQQ  +Q     + +  P+K+   TSPR S         ISD YS     P    
Sbjct: 133 LKKQQQQQSAKQ-----RNQILPSKKNVPTSPRTSPSPYAFSPVISDFYSSLPSQPLDPS 187

Query: 154 TTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSS 213
             A  +    S  S+  + + Q   LVAS P+L S  Y +         + P      SS
Sbjct: 188 NWAWNSTFTESSTSDFQMQDTQWERLVASVPALYSDAYDI--FQIIELYNLPDENEISSS 245

Query: 214 YFSGLDPYLSPMVPQLG--GPALSPLSGPSVGPSLAQSPTSLSGQSYGAYSPVDSLEFK 270
            F  L  YLSP   Q+G  G +LS  +GP+VG S AQ+  +++ Q++ AYS  DSLEF+
Sbjct: 246 SFHCLYQYLSPTKYQVGGQGSSLSIFAGPAVGLSPAQTWPNMTSQAFEAYSLTDSLEFQ 304


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score =  111 bits (277), Expect = 9e-25
 Identities = 84/233 (36%), Positives = 110/233 (47%), Gaps = 30/233 (12%)

Query: 27  HQAVPYPSAP-------------RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVA 73
           HQ+ PY + P             RKQRR RTTFT +QL+ELE +FA+T YPD+Y REE+A
Sbjct: 73  HQSSPYAAVPYKLFTDHGGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELA 132

Query: 74  LKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPP--GGQAKARPAKRKAGTSPRPSTDV 131
           LKI+L E+RVQVWF+NRRAK R+Q +           G   K   + R   +    STD 
Sbjct: 133 LKIDLTEARVQVWFQNRRAKFRKQERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTD- 191

Query: 132 CPDPLGISDSYSPPLP------GPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPS 185
            PD  G       P P      G  G P+ A A      P +  P       G   +  +
Sbjct: 192 -PDSTGGPGPNPNPTPSCGANGGGGGGPSPAGA------PGAAGPGGPGGEPGKGGAAAA 244

Query: 186 LTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLS 238
             +A  A   A A+A     +A G    +  G  P ++ +   LGGP  S LS
Sbjct: 245 AAAAAAAAAAAAAAAAGGLAAAGGPGQGWAPGPGP-ITSIPDSLGGPFASVLS 296


>gi|46249382 paired-like homeobox 2a [Homo sapiens]
          Length = 284

 Score =  110 bits (274), Expect = 2e-24
 Identities = 76/212 (35%), Positives = 105/212 (49%), Gaps = 28/212 (13%)

Query: 27  HQAVPYPSAP-------------RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVA 73
           HQ  PY + P             RKQRR RTTFT +QL+ELE +FA+T YPD+Y REE+A
Sbjct: 65  HQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELA 124

Query: 74  LKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCP 133
           LKI+L E+RVQVWF+NRRAK R  +Q++    +   G A A+  + +  +    S +   
Sbjct: 125 LKIDLTEARVQVWFQNRRAKFR--KQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTC 182

Query: 134 DPLGISDSYSPPLPGPS-GSP--TTAVATVSIWSPASESPLPEAQRAGLVA-------SG 183
            P   S +  PP P P   SP  + +   V++ S     P P+  +  L A        G
Sbjct: 183 SPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGG 242

Query: 184 PSLTSAPYAMTYAPASAFCSSPSAYGSPSSYF 215
           P   +A     + PA    S P  +    S F
Sbjct: 243 PGAGAAELLKAWQPAE---SGPGPFSGVLSSF 271


>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
           sapiens]
          Length = 377

 Score =  107 bits (268), Expect = 1e-23
 Identities = 89/247 (36%), Positives = 122/247 (49%), Gaps = 33/247 (13%)

Query: 12  SVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREE 71
           SV+AL L+    D++ +A  Y S  RKQRR RT FT  QLE LE  F KT YPDV  RE 
Sbjct: 40  SVHALTLAERLADIILEA-RYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRER 98

Query: 72  VALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDV 131
           +A+  NLPE+RVQVWFKNRRAK R++++  +++Q     +A+    + KA  +P P T +
Sbjct: 99  LAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKA-EAPTPDTQL 157

Query: 132 CPDPLGISDSYSPP-LPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAP 190
                   D+  PP LP   GS   A   +S+   ++    PE Q        P     P
Sbjct: 158 --------DTEQPPRLP---GSDPPAELHLSLSEQSASESAPEDQ--------PDREEDP 198

Query: 191 YAMTYAPASAFCSSPSAYGSPSSYFSGLD-PYLSPMVPQLGGPALSPLS--GPSVGPSLA 247
                    A    P A  SP +   GL     SP     G   ++P++  G  +GPS +
Sbjct: 199 --------RAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLLGPSHS 250

Query: 248 QSPTSLS 254
            S + LS
Sbjct: 251 YSSSPLS 257


>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
           sapiens]
          Length = 382

 Score =  103 bits (257), Expect = 2e-22
 Identities = 87/252 (34%), Positives = 118/252 (46%), Gaps = 32/252 (12%)

Query: 7   PGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDV 66
           P  H    A  L+G +   +     Y S  RKQRR RT FT  QLE LE  F KT YPDV
Sbjct: 39  PSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDV 98

Query: 67  YAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPR 126
             RE +A+  NLPE+RVQVWFKNRRAK R++++  +++Q     +A+    + KA  +P 
Sbjct: 99  VMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKA-EAPT 157

Query: 127 PSTDVCPDPLGISDSYSPP-LPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPS 185
           P T +        D+  PP LP   GS   A   +S+   ++    PE Q        P 
Sbjct: 158 PDTQL--------DTEQPPRLP---GSDPPAELHLSLSEQSASESAPEDQ--------PD 198

Query: 186 LTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD-PYLSPMVPQLGGPALSPLS--GPSV 242
               P         A    P A  SP +   GL     SP     G   ++P++  G  +
Sbjct: 199 REEDP--------RAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLL 250

Query: 243 GPSLAQSPTSLS 254
           GPS + S + LS
Sbjct: 251 GPSHSYSSSPLS 262


>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
          Length = 302

 Score =  100 bits (250), Expect = 1e-21
 Identities = 75/205 (36%), Positives = 97/205 (47%), Gaps = 29/205 (14%)

Query: 34  SAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAK 93
           S  +KQRR+RT FT  QL+ELEA F + +YPD+  REE+A+  NL E+RV+VWFKNRRAK
Sbjct: 57  SLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 116

Query: 94  CRQQRQQQKQQ------QQPPGG-----------------QAKARPAKRKAGTSPRPSTD 130
            R++ + Q+ +        P GG                   KA      A T P     
Sbjct: 117 WRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNS 176

Query: 131 VCPDPLGISDSYSPPLP-GPSGSPTTAVATVSIWSPASESPL---PEAQRAGLVASGPSL 186
           V   PL     +SPP     S  P+ A A  ++  P +   L   P       V+SG   
Sbjct: 177 VNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSG--A 234

Query: 187 TSAPYAMTYAPASAFCSSPSAYGSP 211
            S PYA   A A+A  SSP  Y  P
Sbjct: 235 VSCPYASAAAAAAAAASSPYVYRDP 259


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score =  100 bits (249), Expect = 2e-21
 Identities = 75/215 (34%), Positives = 102/215 (47%), Gaps = 35/215 (16%)

Query: 37  RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQ 96
           RKQRR RTTFT  QLEELE  F KT YPDV+ REE+A++++L E+RVQVWF+NRRAK R+
Sbjct: 326 RKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRK 385

Query: 97  QRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTA 156
                                + KAG    P     P PL  +   SP L   S  P   
Sbjct: 386 ---------------------REKAGAQTHPPGLPFPGPLSATHPLSPYLDA-SPFPPHH 423

Query: 157 VATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFS 216
            A  S W+ A+         A   A+ PSL   P + +  P+ A     +  G+      
Sbjct: 424 PALDSAWTAAA---------AAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHP 474

Query: 217 GLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPT 251
               ++SP   +L    ++PL+  S   +L + PT
Sbjct: 475 A---FISPAFGRLFS-TMAPLTSASTAAALLRQPT 505


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 59/140 (42%), Positives = 74/140 (52%), Gaps = 8/140 (5%)

Query: 37  RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQ 96
           +K RR RTTFT  QL ELE  F K+ YPDVY+REE+A K+NLPE RVQVWF+NRRAK R+
Sbjct: 134 KKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRR 193

Query: 97  QRQ----QQKQQQQPPGGQAKARPAKRKA--GTSPRPSTDVCPDPLGISDSYSPPLPGPS 150
           Q +      K Q  P    +++ P+   +  G  P          L +     PPLPG  
Sbjct: 194 QEKLEVSSMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWLGPPLPG-- 251

Query: 151 GSPTTAVATVSIWSPASESP 170
           G  T   +      PA   P
Sbjct: 252 GGATALQSLPGFGPPAQSLP 271



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 5/68 (7%)

Query: 185 SLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGP 244
           S + +P + T +P  A    P + G P+     L+ +L P +P  G  AL  L  P  GP
Sbjct: 211 SFSRSPPSATLSPLGA---GPGSGGGPAGGALPLESWLGPPLPGGGATALQSL--PGFGP 265

Query: 245 SLAQSPTS 252
                P S
Sbjct: 266 PAQSLPAS 273


>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
          Length = 268

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 52/94 (55%), Positives = 65/94 (69%), Gaps = 5/94 (5%)

Query: 37  RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQ 96
           RKQRR RTTFT  QLE LEA+FA+T YPDV+ REE+A+KINL E+RVQVWF+NRRAK R 
Sbjct: 36  RKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWR- 94

Query: 97  QRQQQKQQQQPPGGQ---AKARPAKRKAGTSPRP 127
            + ++    Q PG +   A+  P   +   SP P
Sbjct: 95  -KTERGASDQEPGAKEPMAEVTPPPVRNINSPPP 127


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 73/220 (33%), Positives = 104/220 (47%), Gaps = 29/220 (13%)

Query: 37  RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQ 96
           RKQRR RTTFT  QLEELE  F +T YPD+Y REE+A +  L E+RVQVWF NRRA+ R+
Sbjct: 215 RKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRK 274

Query: 97  QRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTA 156
           Q           G    A       G  P       P P  + D         S  PTT 
Sbjct: 275 Q----------AGANQLAAFNHLLPGGFPPTGMPTLP-PYQLPD---------STYPTTT 314

Query: 157 VATVSIWSPASESPLPEA--QRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSY 214
           ++     +     PLP +   + GL A+     +A  +  Y    +F S   ++ +P++ 
Sbjct: 315 ISQDGGSTVHRPQPLPPSTMHQGGLAAAA---AAADTSSAYGARHSFSSYSDSFMNPAAP 371

Query: 215 FSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLS 254
            + ++P  + + PQ+    +S L  PS  P   Q+  S+S
Sbjct: 372 SNHMNPVSNGLSPQV----MSILGNPSAVPPQPQADFSIS 407


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 73/220 (33%), Positives = 104/220 (47%), Gaps = 29/220 (13%)

Query: 37  RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQ 96
           RKQRR RTTFT  QLEELE  F +T YPD+Y REE+A +  L E+RVQVWF NRRA+ R+
Sbjct: 213 RKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRK 272

Query: 97  QRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTA 156
           Q           G    A       G  P       P P  + D         S  PTT 
Sbjct: 273 Q----------AGANQLAAFNHLLPGGFPPTGMPTLP-PYQLPD---------STYPTTT 312

Query: 157 VATVSIWSPASESPLPEA--QRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSY 214
           ++     +     PLP +   + GL A+     +A  +  Y    +F S   ++ +P++ 
Sbjct: 313 ISQDGGSTVHRPQPLPPSTMHQGGLAAAA---AAADTSSAYGARHSFSSYSDSFMNPAAP 369

Query: 215 FSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLS 254
            + ++P  + + PQ+    +S L  PS  P   Q+  S+S
Sbjct: 370 SNHMNPVSNGLSPQV----MSILGNPSAVPPQPQADFSIS 405


>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 73/220 (33%), Positives = 104/220 (47%), Gaps = 29/220 (13%)

Query: 37  RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQ 96
           RKQRR RTTFT  QLEELE  F +T YPD+Y REE+A +  L E+RVQVWF NRRA+ R+
Sbjct: 215 RKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRK 274

Query: 97  QRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTA 156
           Q           G    A       G  P       P P  + D         S  PTT 
Sbjct: 275 Q----------AGANQLAAFNHLLPGGFPPTGMPTLP-PYQLPD---------STYPTTT 314

Query: 157 VATVSIWSPASESPLPEA--QRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSY 214
           ++     +     PLP +   + GL A+     +A  +  Y    +F S   ++ +P++ 
Sbjct: 315 ISQDGGSTVHRPQPLPPSTMHQGGLAAAA---AAADTSSAYGARHSFSSYSDSFMNPAAP 371

Query: 215 FSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLS 254
            + ++P  + + PQ+    +S L  PS  P   Q+  S+S
Sbjct: 372 SNHMNPVSNGLSPQV----MSILGNPSAVPPQPQADFSIS 407


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 71/237 (29%), Positives = 104/237 (43%), Gaps = 37/237 (15%)

Query: 37  RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQ 96
           RK +R RT+FT+ Q+E LE  F +T YPDV+ARE +A KI+LPE+R+QVWF NRRAK R+
Sbjct: 208 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 267

Query: 97  QRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTA 156
           + + + Q++Q                          P  + IS S+S  +  P   PTT 
Sbjct: 268 EEKLRNQRRQASN----------------------TPSHIPISSSFSTSVYQPIPQPTTP 305

Query: 157 VATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFS 216
           V++ +  S    +          +   PS T A       P  +  SS S          
Sbjct: 306 VSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSC--------- 356

Query: 217 GLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSG-QSYGAYSPVDSLEFKDP 272
                + P  P + G +    + P +   +   P   SG  S G  SP  S+  + P
Sbjct: 357 -----MLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVP 408


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 71/237 (29%), Positives = 104/237 (43%), Gaps = 37/237 (15%)

Query: 37  RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQ 96
           RK +R RT+FT+ Q+E LE  F +T YPDV+ARE +A KI+LPE+R+QVWF NRRAK R+
Sbjct: 222 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 281

Query: 97  QRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTA 156
           + + + Q++Q                          P  + IS S+S  +  P   PTT 
Sbjct: 282 EEKLRNQRRQASN----------------------TPSHIPISSSFSTSVYQPIPQPTTP 319

Query: 157 VATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFS 216
           V++ +  S    +          +   PS T A       P  +  SS S          
Sbjct: 320 VSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSC--------- 370

Query: 217 GLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSG-QSYGAYSPVDSLEFKDP 272
                + P  P + G +    + P +   +   P   SG  S G  SP  S+  + P
Sbjct: 371 -----MLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVP 422


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 71/237 (29%), Positives = 104/237 (43%), Gaps = 37/237 (15%)

Query: 37  RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQ 96
           RK +R RT+FT+ Q+E LE  F +T YPDV+ARE +A KI+LPE+R+QVWF NRRAK R+
Sbjct: 208 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 267

Query: 97  QRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTA 156
           + + + Q++Q                          P  + IS S+S  +  P   PTT 
Sbjct: 268 EEKLRNQRRQASN----------------------TPSHIPISSSFSTSVYQPIPQPTTP 305

Query: 157 VATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFS 216
           V++ +  S    +          +   PS T A       P  +  SS S          
Sbjct: 306 VSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSC--------- 356

Query: 217 GLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSG-QSYGAYSPVDSLEFKDP 272
                + P  P + G +    + P +   +   P   SG  S G  SP  S+  + P
Sbjct: 357 -----MLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVP 408


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score = 95.9 bits (237), Expect = 4e-20
 Identities = 84/262 (32%), Positives = 112/262 (42%), Gaps = 40/262 (15%)

Query: 18  LSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKIN 77
           + GP      Q    P  P ++RR RT FT+ QL+ELE  F ++QYPDV ARE +A ++N
Sbjct: 118 VEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLN 177

Query: 78  LPESRVQVWFKNRRAKCRQQRQQQKQQQQPP-----------GGQAKARPAKRKA----- 121
           L E RVQVWF+NRRAK ++ ++    +               GG   A PA   A     
Sbjct: 178 LTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHL 237

Query: 122 -GTSPRPST----DVCPDPLGISDSYSPPL-------PGPSGS------PTTAVATVSIW 163
               PRP       + P P  +     PP+       P P GS      P   +A V  W
Sbjct: 238 VPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPW 297

Query: 164 SPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLS 223
            P   +P+P       V +GP +   P     A        P A   P    + L P   
Sbjct: 298 PPM--APVPPWPPMAPVPTGPPMAPVPPGPPMARVPP--GPPMARVPPGPPMAPLPPG-P 352

Query: 224 PMVPQLGGPALSPL-SGPSVGP 244
           PM P   GP ++PL  GP + P
Sbjct: 353 PMAPLPPGPPMAPLPPGPPMAP 374


>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
          Length = 343

 Score = 94.4 bits (233), Expect = 1e-19
 Identities = 84/242 (34%), Positives = 109/242 (45%), Gaps = 41/242 (16%)

Query: 6   NPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPD 65
           +PGP  +   L LS    D M  A        K+RR RTTF+  QLEELE +F KT YPD
Sbjct: 124 SPGPCLASLHLPLSPGLPDSMELA----KNKSKKRRNRTTFSTFQLEELEKVFQKTHYPD 179

Query: 66  VYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSP 125
           VYARE++AL+ +L E+RVQVWF+NRRAK R++ +  K Q+          P       S 
Sbjct: 180 VYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQE-------GRNPFTAAYDISV 232

Query: 126 RPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPS 185
            P TD  P  L  S   SP    P G             P   SP       G+    PS
Sbjct: 233 LPRTDSHPQ-LQNSLWASPGSGSPGG-------------PCLVSP------EGI----PS 268

Query: 186 LTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLS-GPSVGP 244
              +PY+  +   + F   P+   +    +S     +    P LGG +  P S G    P
Sbjct: 269 PCMSPYSHPHGSVAGFMGVPAPSAAHPGIYS-----IHGFPPTLGGHSFEPSSDGDYKSP 323

Query: 245 SL 246
           SL
Sbjct: 324 SL 325


>gi|7706659 paired related homeobox 2 [Homo sapiens]
          Length = 253

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 55/126 (43%), Positives = 75/126 (59%), Gaps = 6/126 (4%)

Query: 37  RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQ 96
           +KQRR RTTF  SQL+ LE +F +T YPD + REE+A ++NL E+RVQVWF+NRRAK R+
Sbjct: 102 KKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRR 161

Query: 97  QRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLG--ISDSYS---PPLPGPSG 151
             +     +     ++ ++ A  +   +PRP T + PD L    S  YS   P  PG SG
Sbjct: 162 NERAMLASRSASLLKSYSQEAAIEQPVAPRP-TALSPDYLSWTASSPYSTVPPYSPGSSG 220

Query: 152 SPTTAV 157
             T  V
Sbjct: 221 PATPGV 226


>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
          Length = 411

 Score = 92.4 bits (228), Expect = 4e-19
 Identities = 68/176 (38%), Positives = 87/176 (49%), Gaps = 25/176 (14%)

Query: 10  HYSVNALALSGPSVDLMHQAVPYP-------SAPRKQRRERTTFTRSQLEELEALFAKTQ 62
           + SV    + GP  D     +P P       S   K+RR RTTFT  QLEELE +F KT 
Sbjct: 179 YLSVKEAGVKGPQ-DRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTH 237

Query: 63  YPDVYAREEVALKINLPESRVQVWFKNRRAKCR-QQRQQQKQQQQPPGGQAKARPAKRKA 121
           YPDVYARE++A++ +L E+RVQVWF+NRRAK R ++R  Q QQ +     A   P   +A
Sbjct: 238 YPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRA 297

Query: 122 ----------------GTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVS 161
                             SP P+  V  DP+    S     PG   S  T   +VS
Sbjct: 298 ENYAQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVS 353


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score = 91.7 bits (226), Expect = 7e-19
 Identities = 94/304 (30%), Positives = 129/304 (42%), Gaps = 47/304 (15%)

Query: 19  SGPSVDLMHQAVPYPSAP--RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKI 76
           S P  D        P  P  RKQRR RTTFT  QLEELE  F +T YPD+Y REE+A + 
Sbjct: 197 SAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRA 256

Query: 77  NLPESRVQVWFKNRRAKCRQQ---RQQQKQQQQPPGG----QAKARPAKRKAGTSPRPST 129
            L E+RVQVWF NRRA+ R+Q    Q        PGG         P  + + TS +P++
Sbjct: 257 KLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTS 316

Query: 130 DVCPDPLGISD-SYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTS 188
                P  +SD S +   P P    T   +T+     +S +    + R G          
Sbjct: 317 ----IPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGF--------- 363

Query: 189 APYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGP--------ALSPLSGP 240
           + Y  ++ P     S PS   +P +  +GL P +  ++   GG         ALSPL+G 
Sbjct: 364 SSYTDSFVPP----SGPSNPMNP-TIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTG- 417

Query: 241 SVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDP--TGTWKFTYNPMDPL------DYKDQS 292
             G     + ++   Q       +DSL         T+  T   MDP+       Y    
Sbjct: 418 --GLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSK 475

Query: 293 AWKF 296
            W F
Sbjct: 476 PWTF 479


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 81/239 (33%), Positives = 110/239 (46%), Gaps = 36/239 (15%)

Query: 19  SGPSVDLMHQAVPYPSAP--RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKI 76
           S P  D        P  P  RKQRR RTTFT  QLEELE  F +T YPD+Y REE+A + 
Sbjct: 196 SAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRA 255

Query: 77  NLPESRVQVWFKNRRAKCRQQ---RQQQKQQQQPPGG----QAKARPAKRKAGTSPRPST 129
            L E+RVQVWF NRRA+ R+Q    Q        PGG         P  + + TS +P++
Sbjct: 256 KLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTS 315

Query: 130 DVCPDPLGISD-SYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTS 188
                P  +SD S +   P P    T   +T+     +S +    + R G          
Sbjct: 316 ----IPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGF--------- 362

Query: 189 APYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGP--------ALSPLSG 239
           + Y  ++ P     S PS   +P +  +GL P +  ++   GG         ALSPL+G
Sbjct: 363 SSYTDSFVPP----SGPSNPMNP-TIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTG 416


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 81/239 (33%), Positives = 110/239 (46%), Gaps = 36/239 (15%)

Query: 19  SGPSVDLMHQAVPYPSAP--RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKI 76
           S P  D        P  P  RKQRR RTTFT  QLEELE  F +T YPD+Y REE+A + 
Sbjct: 197 SAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRA 256

Query: 77  NLPESRVQVWFKNRRAKCRQQ---RQQQKQQQQPPGG----QAKARPAKRKAGTSPRPST 129
            L E+RVQVWF NRRA+ R+Q    Q        PGG         P  + + TS +P++
Sbjct: 257 KLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTS 316

Query: 130 DVCPDPLGISD-SYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTS 188
                P  +SD S +   P P    T   +T+     +S +    + R G          
Sbjct: 317 ----IPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGF--------- 363

Query: 189 APYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGP--------ALSPLSG 239
           + Y  ++ P     S PS   +P +  +GL P +  ++   GG         ALSPL+G
Sbjct: 364 SSYTDSFVPP----SGPSNPMNP-TIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTG 417


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 81/239 (33%), Positives = 110/239 (46%), Gaps = 36/239 (15%)

Query: 19  SGPSVDLMHQAVPYPSAP--RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKI 76
           S P  D        P  P  RKQRR RTTFT  QLEELE  F +T YPD+Y REE+A + 
Sbjct: 197 SAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRA 256

Query: 77  NLPESRVQVWFKNRRAKCRQQ---RQQQKQQQQPPGG----QAKARPAKRKAGTSPRPST 129
            L E+RVQVWF NRRA+ R+Q    Q        PGG         P  + + TS +P++
Sbjct: 257 KLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTS 316

Query: 130 DVCPDPLGISD-SYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTS 188
                P  +SD S +   P P    T   +T+     +S +    + R G          
Sbjct: 317 ----IPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGF--------- 363

Query: 189 APYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGP--------ALSPLSG 239
           + Y  ++ P     S PS   +P +  +GL P +  ++   GG         ALSPL+G
Sbjct: 364 SSYTDSFVPP----SGPSNPMNP-TIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTG 417


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 75/220 (34%), Positives = 96/220 (43%), Gaps = 34/220 (15%)

Query: 19  SGPSVDLMHQAVPYPSAP--RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKI 76
           S P  D        P  P  RKQRR RTTFT  QLEELE  F +T YPD+Y REE+A + 
Sbjct: 197 SAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRA 256

Query: 77  NLPESRVQVWFKNRRAKCRQQ---RQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCP 133
            L E+RVQVWF NRRA+ R+Q    Q        PGG              P  +    P
Sbjct: 257 KLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGG-------------FPPTAMPTLP 303

Query: 134 DPLGISDSYSP-PLPGPSGSPTTAVATVSIWSPASESPLPEAQ-RAGLVASGPSLTSAPY 191
                  SY P  +P     P++ V            PLP +      + S P  +SA Y
Sbjct: 304 TYQLSETSYQPTSIPQAVSDPSSTV--------HRPQPLPPSTVHQSTIPSNPDSSSA-Y 354

Query: 192 AMTYAPASAFCSSPSAYGSPSSYFSGLDPY----LSPMVP 227
            +  +    F S   ++  PS   + ++P     LSP VP
Sbjct: 355 CLP-STRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVP 393


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 75/220 (34%), Positives = 96/220 (43%), Gaps = 34/220 (15%)

Query: 19  SGPSVDLMHQAVPYPSAP--RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKI 76
           S P  D        P  P  RKQRR RTTFT  QLEELE  F +T YPD+Y REE+A + 
Sbjct: 197 SAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRA 256

Query: 77  NLPESRVQVWFKNRRAKCRQQ---RQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCP 133
            L E+RVQVWF NRRA+ R+Q    Q        PGG              P  +    P
Sbjct: 257 KLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGG-------------FPPTAMPTLP 303

Query: 134 DPLGISDSYSP-PLPGPSGSPTTAVATVSIWSPASESPLPEAQ-RAGLVASGPSLTSAPY 191
                  SY P  +P     P++ V            PLP +      + S P  +SA Y
Sbjct: 304 TYQLSETSYQPTSIPQAVSDPSSTV--------HRPQPLPPSTVHQSTIPSNPDSSSA-Y 354

Query: 192 AMTYAPASAFCSSPSAYGSPSSYFSGLDPY----LSPMVP 227
            +  +    F S   ++  PS   + ++P     LSP VP
Sbjct: 355 CLP-STRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVP 393


>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
          Length = 326

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 42/68 (61%), Positives = 53/68 (77%)

Query: 38  KQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQ 97
           K+RR RTTFT  QLEELE +F KT YPDVY RE++AL+  L E+RVQVWF+NRRAK R++
Sbjct: 131 KKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKR 190

Query: 98  RQQQKQQQ 105
            +  + QQ
Sbjct: 191 ERYGQIQQ 198


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,308,797
Number of Sequences: 37866
Number of extensions: 950727
Number of successful extensions: 8374
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 391
Number of HSP's successfully gapped in prelim test: 737
Number of HSP's that attempted gapping in prelim test: 5182
Number of HSP's gapped (non-prelim): 2666
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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