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Search of human proteins with 4557365
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557365 Bloom syndrome protein [Homo sapiens]
(1417 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557365 Bloom syndrome protein [Homo sapiens] 2838 0.0
gi|14591902 RecQ protein-like [Homo sapiens] 369 e-102
gi|14591904 RecQ protein-like [Homo sapiens] 369 e-102
gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens] 286 1e-76
gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens] 278 3e-74
gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens] 278 3e-74
gi|110735439 Werner syndrome protein [Homo sapiens] 221 4e-57
gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent... 221 4e-57
gi|116812616 RecQ protein-like 4 [Homo sapiens] 171 5e-42
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 74 1e-12
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 73 2e-12
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 73 2e-12
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 72 4e-12
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 67 9e-11
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 65 6e-10
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 64 1e-09
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 58 6e-08
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 58 7e-08
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 57 1e-07
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 56 3e-07
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 55 4e-07
gi|13129006 nucleolar protein GU2 [Homo sapiens] 55 6e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 54 1e-06
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 54 1e-06
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 52 4e-06
gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo sapi... 52 4e-06
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 52 4e-06
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 52 4e-06
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi... 52 4e-06
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 51 7e-06
>gi|4557365 Bloom syndrome protein [Homo sapiens]
Length = 1417
Score = 2838 bits (7357), Expect = 0.0
Identities = 1417/1417 (100%), Positives = 1417/1417 (100%)
Query: 1 MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL 60
MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL
Sbjct: 1 MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL 60
Query: 61 RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC 120
RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC
Sbjct: 61 RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC 120
Query: 121 TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV 180
TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV
Sbjct: 121 TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV 180
Query: 181 STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD 240
STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD
Sbjct: 181 STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD 240
Query: 241 GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF 300
GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF
Sbjct: 241 GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF 300
Query: 301 VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD 360
VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD
Sbjct: 301 VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD 360
Query: 361 CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD 420
CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD
Sbjct: 361 CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD 420
Query: 421 ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS 480
ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS
Sbjct: 421 ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS 480
Query: 481 ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI 540
ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI
Sbjct: 481 ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI 540
Query: 541 NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL 600
NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL
Sbjct: 541 NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL 600
Query: 601 SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH 660
SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH
Sbjct: 601 SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH 660
Query: 661 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI 720
KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI
Sbjct: 661 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI 720
Query: 721 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL 780
VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL
Sbjct: 721 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL 780
Query: 781 ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD 840
ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD
Sbjct: 781 ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD 840
Query: 841 ILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE 900
ILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE
Sbjct: 841 ILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE 900
Query: 901 CDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF 960
CDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
Sbjct: 901 CDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF 960
Query: 961 VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHF 1020
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHF
Sbjct: 961 VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHF 1020
Query: 1021 NNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDD 1080
NNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDD
Sbjct: 1021 NNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDD 1080
Query: 1081 VKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH 1140
VKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
Sbjct: 1081 VKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH 1140
Query: 1141 NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKK 1200
NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKK
Sbjct: 1141 NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKK 1200
Query: 1201 QKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVL 1260
QKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVL
Sbjct: 1201 QKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVL 1260
Query: 1261 LQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP 1320
LQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
Sbjct: 1261 LQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP 1320
Query: 1321 VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSS 1380
VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSS
Sbjct: 1321 VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSS 1380
Query: 1381 SASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS 1417
SASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
Sbjct: 1381 SASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS 1417
>gi|14591902 RecQ protein-like [Homo sapiens]
Length = 649
Score = 369 bits (948), Expect = e-102
Identities = 208/552 (37%), Positives = 313/552 (56%), Gaps = 31/552 (5%)
Query: 649 FPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG 708
FP + ++ I F L FR QLE IN + G++ F++MPTGGGKSLCYQLPA S G
Sbjct: 73 FPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDG 132
Query: 709 VTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPE 768
T+VI PL SL+ DQ+ L L I AT L + ++ ++ K+ +KL+YVTPE
Sbjct: 133 FTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPE 192
Query: 769 KICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMA 828
KI S +S LE YE + R +DE HC SQWGHDFR DYK + +L+++FP+ ++
Sbjct: 193 KIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIG 252
Query: 829 LTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAF--DCLEWIRKHH 886
LTATA V D L I + F+ SFNR NL Y V K F D ++ I +
Sbjct: 253 LTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRY 312
Query: 887 PYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICAT 946
SGIIYC S+++ + + +LQ G+ A AYHA L + V +KW + + QV+ AT
Sbjct: 313 KGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW-SANEIQVVVAT 371
Query: 947 IAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIM 1006
+AFGMGIDKPDVRFVIH S+ KS+E YYQESGRAGRD + C+L+Y + D+ R+ +++
Sbjct: 372 VAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVV 431
Query: 1007 MEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNC 1066
ME G LY MV YC+NI++CRR+ + +F E +N + C K CDNC
Sbjct: 432 MENVGQ--------QKLYEMVSYCQNISKCRRVLMAQHFDE-VWNSEACNK----MCDNC 478
Query: 1067 CKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKI 1126
CK ++ +++T+ + +++ +++ + + T L+D ++G +AK+
Sbjct: 479 CKDSAFERKNITEYCRDLIKILKQAEEL-----------NEKLTPLKLIDSWMGKGAAKL 527
Query: 1127 Q-SGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNL 1185
+ +G+ R + E++ ++ + L ED A I+Y+ +G KA + N
Sbjct: 528 RVAGVV--APTLPREDLEKIIAHFLIQQYLKEDYSFTAY-ATISYLKIGPKANLLNNEAH 584
Query: 1186 KVDFMETENSSS 1197
+ T+++ +
Sbjct: 585 AITMQVTKSTQN 596
>gi|14591904 RecQ protein-like [Homo sapiens]
Length = 649
Score = 369 bits (948), Expect = e-102
Identities = 208/552 (37%), Positives = 313/552 (56%), Gaps = 31/552 (5%)
Query: 649 FPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG 708
FP + ++ I F L FR QLE IN + G++ F++MPTGGGKSLCYQLPA S G
Sbjct: 73 FPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDG 132
Query: 709 VTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPE 768
T+VI PL SL+ DQ+ L L I AT L + ++ ++ K+ +KL+YVTPE
Sbjct: 133 FTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPE 192
Query: 769 KICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMA 828
KI S +S LE YE + R +DE HC SQWGHDFR DYK + +L+++FP+ ++
Sbjct: 193 KIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIG 252
Query: 829 LTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAF--DCLEWIRKHH 886
LTATA V D L I + F+ SFNR NL Y V K F D ++ I +
Sbjct: 253 LTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRY 312
Query: 887 PYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICAT 946
SGIIYC S+++ + + +LQ G+ A AYHA L + V +KW + + QV+ AT
Sbjct: 313 KGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW-SANEIQVVVAT 371
Query: 947 IAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIM 1006
+AFGMGIDKPDVRFVIH S+ KS+E YYQESGRAGRD + C+L+Y + D+ R+ +++
Sbjct: 372 VAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVV 431
Query: 1007 MEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNC 1066
ME G LY MV YC+NI++CRR+ + +F E +N + C K CDNC
Sbjct: 432 MENVGQ--------QKLYEMVSYCQNISKCRRVLMAQHFDE-VWNSEACNK----MCDNC 478
Query: 1067 CKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKI 1126
CK ++ +++T+ + +++ +++ + + T L+D ++G +AK+
Sbjct: 479 CKDSAFERKNITEYCRDLIKILKQAEEL-----------NEKLTPLKLIDSWMGKGAAKL 527
Query: 1127 Q-SGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNL 1185
+ +G+ R + E++ ++ + L ED A I+Y+ +G KA + N
Sbjct: 528 RVAGVV--APTLPREDLEKIIAHFLIQQYLKEDYSFTAY-ATISYLKIGPKANLLNNEAH 584
Query: 1186 KVDFMETENSSS 1197
+ T+++ +
Sbjct: 585 AITMQVTKSTQN 596
>gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]
Length = 991
Score = 286 bits (731), Expect = 1e-76
Identities = 173/435 (39%), Positives = 246/435 (56%), Gaps = 27/435 (6%)
Query: 649 FPHTKEMMKIFHKKFGLHNFRTNQLEAINAALL--GEDCFILMPTGGGKSLCYQLPACVS 706
F + + K FG +F+T E+ A++ +D F+ MPTG GKSLCYQLPA ++
Sbjct: 10 FDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLA 69
Query: 707 PGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVT 766
G+T+V+SPL +LI DQV L +L + + L + E + L ++ P K+LY+T
Sbjct: 70 KGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYIT 129
Query: 767 PEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPV 826
PE + AS+ TL +L R LL+ V+DEAHCVSQWGHDFR DY R+ LR + P
Sbjct: 130 PE-MAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPC 188
Query: 827 MALTATANPRVQKDILTQLKILRP-QVFSMSFNRHNLKYYVLPKKPKKVAFD-----CLE 880
+ALTATA P+VQ+D+ L + +P +F R NL Y V K+ + CL+
Sbjct: 189 VALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLK 248
Query: 881 WIRKHHP---YDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQ 937
+ + GI+YC +R C+ +A L G+ A AYHAGL S R VQ W+ +
Sbjct: 249 ALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWM-E 307
Query: 938 DGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHD 997
+ VI ATI+FGMG+DK +VRFV H ++ KS+ GYYQESGRAGRDG+ S C L+Y+ +D
Sbjct: 308 EKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRND 367
Query: 998 VTRLKRLI------MMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFN 1051
++ LI + EK GN + + ++V +CE + CR + YFG+
Sbjct: 368 RDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEEL-GCRHAAIAKYFGD---A 423
Query: 1052 PDFCKKHPDVSCDNC 1066
C K CD+C
Sbjct: 424 LPACAK----GCDHC 434
>gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens]
Length = 410
Score = 278 bits (711), Expect = 3e-74
Identities = 163/402 (40%), Positives = 233/402 (57%), Gaps = 19/402 (4%)
Query: 649 FPHTKEMMKIFHKKFGLHNFRTNQLEAINAALL--GEDCFILMPTGGGKSLCYQLPACVS 706
F + + K FG +F+T E+ A++ +D F+ MPTG GKSLCYQLPA ++
Sbjct: 10 FDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLA 69
Query: 707 PGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVT 766
G+T+V+SPL +LI DQV L +L + + L + E + L ++ P K+LY+T
Sbjct: 70 KGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYIT 129
Query: 767 PEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPV 826
PE + AS+ TL +L R LL+ V+DEAHCVSQWGHDFR DY R+ LR + P
Sbjct: 130 PE-MAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPC 188
Query: 827 MALTATANPRVQKDILTQLKILRP-QVFSMSFNRHNLKYYVLPKKPKKVAFD-----CLE 880
+ALTATA P+VQ+D+ L + +P +F R NL Y V K+ + CL+
Sbjct: 189 VALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLK 248
Query: 881 WIRKHHPYD---SGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQ 937
+ + GI+YC +R C+ +A L G+ A AYHAGL S R VQ W+ +
Sbjct: 249 ALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWM-E 307
Query: 938 DGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHD 997
+ VI ATI+FGMG+DK +VRFV H ++ KS+ GYYQESGRAGRDG+ S C L+Y+ +D
Sbjct: 308 EKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRND 367
Query: 998 VTRLKRLI------MMEKDGNHHTRETHFNNLYSMVHYCENI 1033
++ LI + EK GN + + ++V +CE +
Sbjct: 368 RDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEEL 409
>gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens]
Length = 435
Score = 278 bits (711), Expect = 3e-74
Identities = 163/402 (40%), Positives = 233/402 (57%), Gaps = 19/402 (4%)
Query: 649 FPHTKEMMKIFHKKFGLHNFRTNQLEAINAALL--GEDCFILMPTGGGKSLCYQLPACVS 706
F + + K FG +F+T E+ A++ +D F+ MPTG GKSLCYQLPA ++
Sbjct: 10 FDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLA 69
Query: 707 PGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVT 766
G+T+V+SPL +LI DQV L +L + + L + E + L ++ P K+LY+T
Sbjct: 70 KGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYIT 129
Query: 767 PEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPV 826
PE + AS+ TL +L R LL+ V+DEAHCVSQWGHDFR DY R+ LR + P
Sbjct: 130 PE-MAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPC 188
Query: 827 MALTATANPRVQKDILTQLKILRP-QVFSMSFNRHNLKYYVLPKKPKKVAFD-----CLE 880
+ALTATA P+VQ+D+ L + +P +F R NL Y V K+ + CL+
Sbjct: 189 VALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLK 248
Query: 881 WIRKHHPYD---SGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQ 937
+ + GI+YC +R C+ +A L G+ A AYHAGL S R VQ W+ +
Sbjct: 249 ALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWM-E 307
Query: 938 DGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHD 997
+ VI ATI+FGMG+DK +VRFV H ++ KS+ GYYQESGRAGRDG+ S C L+Y+ +D
Sbjct: 308 EKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRND 367
Query: 998 VTRLKRLI------MMEKDGNHHTRETHFNNLYSMVHYCENI 1033
++ LI + EK GN + + ++V +CE +
Sbjct: 368 RDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEEL 409
>gi|110735439 Werner syndrome protein [Homo sapiens]
Length = 1432
Score = 221 bits (563), Expect = 4e-57
Identities = 147/426 (34%), Positives = 230/426 (53%), Gaps = 20/426 (4%)
Query: 653 KEMMKIFHKKFGLHNFRTNQLEAINAALLGE-DCFILMPTGGGKSLCYQLPACVSPGVTV 711
+E + FG +F+ Q + I++ L D +M TG GKSLC+Q P + +
Sbjct: 534 EEQVTCLKMYFGHSSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGKIGL 593
Query: 712 VISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKIC 771
VISPL SL+ DQV +L +IPA +L ++++ T+I +L K +++YVTPE
Sbjct: 594 VISPLISLMEDQVLQLKMSNIPACFLGSAQSENVLTDI--KLGK----YRIVYVTPEYCS 647
Query: 772 ASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTA 831
+ L+ LE L+A +DEAHC+S+WGHDFR ++++ L+ P VP++ALTA
Sbjct: 648 GNMGLLQQLEADIGITLIA---VDEAHCISEWGHDFRDSFRKLGSLKTALPMVPIVALTA 704
Query: 832 TANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRK---HHPY 888
TA+ +++DI+ L + PQ+ F+R NL Y + +K + D ++ K H +
Sbjct: 705 TASSSIREDIVRCLNLRNPQITCTGFDRPNL-YLEVRRKTGNILQDLQPFLVKTSSHWEF 763
Query: 889 DS-GIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATI 947
+ IIYC SR+ + L++ L+ YHAG+S S R ++ +++ +D Q + ATI
Sbjct: 764 EGPTIIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFV-RDEIQCVIATI 822
Query: 948 AFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMM 1007
AFGMGI+K D+R VIH PK +E YYQE GRAGRDG S C + + D+ + L+
Sbjct: 823 AFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPADINLNRHLLTE 882
Query: 1008 EKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF-NPDFCKKHPDVSCDNC 1066
+ N R + M Y + + CRR +L++F + + CDNC
Sbjct: 883 IR--NEKFRLYKLKMMAKMEKYLHS-SRCRRQIILSHFEDKQVQKASLGIMGTEKCCDNC 939
Query: 1067 CKTKDY 1072
D+
Sbjct: 940 RSRLDH 945
>gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent
helicase, partial [Homo sapiens]
Length = 1140
Score = 221 bits (563), Expect = 4e-57
Identities = 147/426 (34%), Positives = 230/426 (53%), Gaps = 20/426 (4%)
Query: 653 KEMMKIFHKKFGLHNFRTNQLEAINAALLGE-DCFILMPTGGGKSLCYQLPACVSPGVTV 711
+E + FG +F+ Q + I++ L D +M TG GKSLC+Q P + +
Sbjct: 242 EEQVTCLKMYFGHSSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGKIGL 301
Query: 712 VISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKIC 771
VISPL SL+ DQV +L +IPA +L ++++ T+I +L K +++YVTPE
Sbjct: 302 VISPLISLMEDQVLQLKMSNIPACFLGSAQSENVLTDI--KLGK----YRIVYVTPEYCS 355
Query: 772 ASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTA 831
+ L+ LE L+A +DEAHC+S+WGHDFR ++++ L+ P VP++ALTA
Sbjct: 356 GNMGLLQQLEADIGITLIA---VDEAHCISEWGHDFRDSFRKLGSLKTALPMVPIVALTA 412
Query: 832 TANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRK---HHPY 888
TA+ +++DI+ L + PQ+ F+R NL Y + +K + D ++ K H +
Sbjct: 413 TASSSIREDIVRCLNLRNPQITCTGFDRPNL-YLEVRRKTGNILQDLQPFLVKTSSHWEF 471
Query: 889 DS-GIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATI 947
+ IIYC SR+ + L++ L+ YHAG+S S R ++ +++ +D Q + ATI
Sbjct: 472 EGPTIIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFV-RDEIQCVIATI 530
Query: 948 AFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMM 1007
AFGMGI+K D+R VIH PK +E YYQE GRAGRDG S C + + D+ + L+
Sbjct: 531 AFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPADINLNRHLLTE 590
Query: 1008 EKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF-NPDFCKKHPDVSCDNC 1066
+ N R + M Y + + CRR +L++F + + CDNC
Sbjct: 591 IR--NEKFRLYKLKMMAKMEKYLHS-SRCRRQIILSHFEDKQVQKASLGIMGTEKCCDNC 647
Query: 1067 CKTKDY 1072
D+
Sbjct: 648 RSRLDH 653
>gi|116812616 RecQ protein-like 4 [Homo sapiens]
Length = 1208
Score = 171 bits (433), Expect = 5e-42
Identities = 122/352 (34%), Positives = 177/352 (50%), Gaps = 28/352 (7%)
Query: 661 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACV----SPGVTVVISPL 716
++ G FR Q A+ L G +++PTG GKSLCYQLPA + SP +T+V+SPL
Sbjct: 474 EQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPL 533
Query: 717 RSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRL 776
SL+ DQV L + A + T + ++ ++ + +L +TPE + + L
Sbjct: 534 LSLMDDQVSGLPPC-LKAACIHSGMTRKQRESVLQKIRAAQ--VHVLMLTPEALVGAGGL 590
Query: 777 ISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRM-NMLRQKFPSVPVMALTATANP 835
+ +A IDEAHC+SQW H+FR Y R+ +LR++ + LTATA
Sbjct: 591 PPAAQ----LPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATR 646
Query: 836 RVQKDILTQLKILR-PQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIY 894
R D+ L + P + + NL V + A L ++ DS IIY
Sbjct: 647 RTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIY 706
Query: 895 CLSRRECDTMADTLQR--------------DGLAALAYHAGLSDSARDEVQQKWINQDGC 940
C R + + +A L+ A AYHAG+ R VQ+ ++ Q
Sbjct: 707 CNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFM-QGQL 765
Query: 941 QVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLF 992
+V+ AT+AFGMG+D+PDVR V+H LP S E Y Q GRAGRDG+ +HC LF
Sbjct: 766 RVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLF 817
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 73.9 bits (180), Expect = 1e-12
Identities = 93/361 (25%), Positives = 148/361 (40%), Gaps = 37/361 (10%)
Query: 672 QLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG-----------VTVVISPLRSLI 720
Q + AL G D + TG GK+L Y LPA V + +V++P R L
Sbjct: 121 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTREL- 179
Query: 721 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL 780
QVQ++ + A L ++T IY K I L I RLI L
Sbjct: 180 AQQVQQVAAEYCRACRL-------KSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFL 232
Query: 781 E----NLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPR 836
E NL L V+DEA + G + Q K ++ +R ++ A +
Sbjct: 233 ECGKTNLRRTTYL---VLDEADRMLDMGFE-PQIRKIVDQIRPDRQTLMWSATWPKEVRQ 288
Query: 837 VQKDILTQLKILRPQVFSMSFNRHNLKYYV-----LPKKPKKVAFDCLEWIRKHHPYDSG 891
+ +D L + +S N HN+ V + K K + +E I +
Sbjct: 289 LAEDFLKDYIHINIGALELSAN-HNILQIVDVCHDVEKDEKLIRL--MEEIMSEKE-NKT 344
Query: 892 IIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGM 951
I++ ++R CD + ++RDG A+ H S RD V ++ ++ AT
Sbjct: 345 IVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEF-KHGKAPILIATDVASR 403
Query: 952 GIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDG 1011
G+D DV+FVI+ P S E Y GR R + F+T +++ ++ LI + ++
Sbjct: 404 GLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREA 463
Query: 1012 N 1012
N
Sbjct: 464 N 464
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 73.2 bits (178), Expect = 2e-12
Identities = 89/356 (25%), Positives = 143/356 (40%), Gaps = 27/356 (7%)
Query: 672 QLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG-----------VTVVISPLRSLI 720
Q + AL G D + TG GK+L Y LPA V + +V++P R L
Sbjct: 198 QCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTREL- 256
Query: 721 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL 780
QVQ++ Y G + ++T IY K I L I RLI L
Sbjct: 257 AQQVQQVAD-----DY--GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFL 309
Query: 781 EN-LYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQK 839
E+ + V+DEA + G + Q K ++ +R ++ A ++ +
Sbjct: 310 ESGKTNLRRCTYLVLDEADRMLDMGFE-PQIRKIVDQIRPDRQTLMWSATWPKEVRQLAE 368
Query: 840 DILTQLKILRPQVFSMSFNRHNLKYYV---LPKKPKKVAFDCLEWIRKHHPYDSGIIYCL 896
D L + +S N HN+ V + + +E I + II+
Sbjct: 369 DFLRDYTQINVGNLELSAN-HNILQIVDVCMESEKDHKLIQLMEEIMAEKE-NKTIIFVE 426
Query: 897 SRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKP 956
++R CD + ++RDG A+ H S RD V ++ ++ AT G+D
Sbjct: 427 TKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEF-RSGKAPILIATDVASRGLDVE 485
Query: 957 DVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGN 1012
DV+FVI+ P S E Y GR R F+T ++ + + LI + ++ N
Sbjct: 486 DVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEAN 541
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 73.2 bits (178), Expect = 2e-12
Identities = 89/356 (25%), Positives = 143/356 (40%), Gaps = 27/356 (7%)
Query: 672 QLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG-----------VTVVISPLRSLI 720
Q + AL G D + TG GK+L Y LPA V + +V++P R L
Sbjct: 198 QCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTREL- 256
Query: 721 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL 780
QVQ++ Y G + ++T IY K I L I RLI L
Sbjct: 257 AQQVQQVAD-----DY--GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFL 309
Query: 781 EN-LYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQK 839
E+ + V+DEA + G + Q K ++ +R ++ A ++ +
Sbjct: 310 ESGKTNLRRCTYLVLDEADRMLDMGFE-PQIRKIVDQIRPDRQTLMWSATWPKEVRQLAE 368
Query: 840 DILTQLKILRPQVFSMSFNRHNLKYYV---LPKKPKKVAFDCLEWIRKHHPYDSGIIYCL 896
D L + +S N HN+ V + + +E I + II+
Sbjct: 369 DFLRDYTQINVGNLELSAN-HNILQIVDVCMESEKDHKLIQLMEEIMAEKE-NKTIIFVE 426
Query: 897 SRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKP 956
++R CD + ++RDG A+ H S RD V ++ ++ AT G+D
Sbjct: 427 TKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEF-RSGKAPILIATDVASRGLDVE 485
Query: 957 DVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGN 1012
DV+FVI+ P S E Y GR R F+T ++ + + LI + ++ N
Sbjct: 486 DVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEAN 541
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 [Homo
sapiens]
Length = 455
Score = 72.0 bits (175), Expect = 4e-12
Identities = 91/349 (26%), Positives = 144/349 (41%), Gaps = 37/349 (10%)
Query: 672 QLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVT------VVISPLRSL---IVD 722
Q+EAI AL G D L TG GK+ + LP + T +V++P R L I +
Sbjct: 51 QIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISE 110
Query: 723 QVQKL-TSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLE 781
Q + L +S+ + + + G DS + + L L+KK II I RLI LE
Sbjct: 111 QFEALGSSIGVQSAVIVGG-IDSMSQS--LALAKKPHII---------IATPGRLIDHLE 158
Query: 782 NL--YERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQK 839
N + + L V+DEA + + D + R + +AT +VQK
Sbjct: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR----KTFLFSATMTKKVQK 214
Query: 840 DILTQLKILRPQVFSMSFNRHNLK----YYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYC 895
L + + P ++S ++ YY+ P K L +I +S +I+C
Sbjct: 215 --LQRAALKNPVKCAVSSKYQTVEKLQQYYIFI--PSKFKDTYLVYILNELAGNSFMIFC 270
Query: 896 LSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDK 955
+ A L+ G A+ H +S S R K+ ++ AT G+D
Sbjct: 271 STCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKF-KAKARSILLATDVASRGLDI 329
Query: 956 PDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRL 1004
P V V++ +P + Y GR R G + F T +DV +R+
Sbjct: 330 PHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRI 378
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 67.4 bits (163), Expect = 9e-11
Identities = 80/358 (22%), Positives = 145/358 (40%), Gaps = 33/358 (9%)
Query: 656 MKIFH--KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPA--------CV 705
MKI + KK G Q +AI A + G D + TG GK++ + LP +
Sbjct: 381 MKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSL 440
Query: 706 SPG---VTVVISPLRSLIVD------QVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKK 756
G + V+++P R L + + K L + Y T I Q+++
Sbjct: 441 EEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVY--------GGTGISEQIAEL 492
Query: 757 DPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNM 816
+++ TP ++ + L + + + + V+DEA + G + Q + ++
Sbjct: 493 KRGAEIIVCTPGRMI--DMLAANSGRVTNLRRVTYVVLDEADRMFDMGFE-PQVMRIVDN 549
Query: 817 LRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAF 876
+R +V A A + + IL+ K + QV S +++ V+ + +K
Sbjct: 550 VRPDRQTVMFSATFPRAMEALARRILS--KPIEVQVGGRSVVCSDVEQQVIVIEEEKKFL 607
Query: 877 DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWIN 936
LE + + S II+ + D + L R ++ H G+ RD + + N
Sbjct: 608 KLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKN 667
Query: 937 QDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYT 994
C+++ AT G+D + V++ S P E Y +GR GR G + F T
Sbjct: 668 GT-CKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFIT 724
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapiens]
Length = 483
Score = 64.7 bits (156), Expect = 6e-10
Identities = 83/344 (24%), Positives = 142/344 (41%), Gaps = 28/344 (8%)
Query: 672 QLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGV------TVVISPLRSLIVDQVQ 725
Q E+I AL G D G GKS Y +P + +VI P R L + Q
Sbjct: 123 QEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQ 182
Query: 726 KLTSLDIPATYLTGDKT--DSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENL 783
+ + ++ G K + TN+ + + D + ++ TP +I L + +
Sbjct: 183 ICIQV---SKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRI-----LDLIKKGV 234
Query: 784 YERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILT 843
+ + V+DEA + DF Q + + + K + ++ +AT VQK + +
Sbjct: 235 AKVDHVQMIVLDEADKLLS--QDFVQIMEDIILTLPK--NRQILLYSATFPLSVQKFMNS 290
Query: 844 QLKILRPQVFSMSFN---RHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE 900
L+ +P ++ + +YY + +KV CL + + II+C S +
Sbjct: 291 HLQ--KPYEINLMEELTLKGVTQYYAYVTERQKV--HCLNTLFSRLQINQSIIFCNSSQR 346
Query: 901 CDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF 960
+ +A + + G + HA + R+ V + N C+ + T F GID V
Sbjct: 347 VELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRN-GLCRNLVCTDLFTRGIDIQAVNV 405
Query: 961 VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRL 1004
VI+ PK E Y GR+GR G + + TY D LK +
Sbjct: 406 VINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSI 449
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 63.5 bits (153), Expect = 1e-09
Identities = 88/386 (22%), Positives = 146/386 (37%), Gaps = 51/386 (13%)
Query: 650 PHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGV 709
PH E++ K G Q +AI L D + TG GK+ + +P V
Sbjct: 400 PHILEVID----KCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITT 455
Query: 710 TVVISPLR-------SLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKL 762
I + ++I+ ++L T G + +S++D +L
Sbjct: 456 LPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRL 515
Query: 763 LYVTPEKICASNRLISTLENLYERKLLAR---FVIDEAHCVSQWGH-------------- 805
I RLI LEN Y +L+R V+DEA + G
Sbjct: 516 RMGCEIVIATPGRLIDVLENRY--LVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVS 573
Query: 806 ------DFRQDYKRM--NMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMS- 856
D +D ++M N K + TAT P V++ L + + RP V +
Sbjct: 574 NQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVER--LARSYLRRPAVVYIGS 631
Query: 857 ----FNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE-CDTMADTLQRD 911
R K +++ + K+ + +D II +++++ CD +A +L++
Sbjct: 632 AGKPHERVEQKVFLMSESEKRKKLLAI----LEQGFDPPIIIFVNQKKGCDVLAKSLEKM 687
Query: 912 GLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVE 971
G A H G R+ + ++ AT G GID DV V++ + K++E
Sbjct: 688 GYNACTLHGGKGQEQREFALSN-LKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIE 746
Query: 972 GYYQESGRAGRDGEISHCLLFYTYHD 997
Y GR GR G+ + F T D
Sbjct: 747 DYIHRIGRTGRAGKSGVAITFLTKED 772
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 58.2 bits (139), Expect = 6e-08
Identities = 80/361 (22%), Positives = 153/361 (42%), Gaps = 29/361 (8%)
Query: 644 FQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPA 703
F+ S P E++ KK G Q++ I LLG D TG GK+ + LP
Sbjct: 205 FEHCSLP---EVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPV 261
Query: 704 CV-------SPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYL--QLS 754
+ +P ++++P R L + ++ L + L KT + L QL
Sbjct: 262 IMRALFESKTPSA-LILTPTRELAIQIERQAKEL---MSGLPRMKTVLLVGGLPLPPQLY 317
Query: 755 KKDPIIKLLYVTPEKICASNRLISTL-ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKR 813
+ +K++ TP RL+ + ++ E + V+DEA + + G +Q
Sbjct: 318 RLQQHVKVIIATP------GRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQ-QQVLDI 370
Query: 814 MNMLRQKFPSVPVMALTATANPRVQKDIL-TQLKILRPQVFSMSFNRHNLKYYVLPKKPK 872
+ + ++ V A T+ ++ +L ++I+ + N + +V K
Sbjct: 371 LENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKK 430
Query: 873 KVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQR-DGLAALAYHAGLSDSARDEVQ 931
K F+ L + P + C + D +++ +Q+ GL +++ H+ S R +
Sbjct: 431 KKLFEILNDKKLFKPPVLVFVDC--KLGADLLSEAVQKITGLKSISIHSEKSQIERKNIL 488
Query: 932 QKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLL 991
+ + D +V+ +T G G+D VR V++ +P S++ Y + GR GR G+ +
Sbjct: 489 KGLLEGD-YEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAIT 547
Query: 992 F 992
F
Sbjct: 548 F 548
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 57.8 bits (138), Expect = 7e-08
Identities = 94/456 (20%), Positives = 179/456 (39%), Gaps = 53/456 (11%)
Query: 565 DDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQ 624
D + + A K S Q +E + ++SV+E + + V A+ I + + I+
Sbjct: 89 DQHQHLKEKAEARKESAKEKQLKEEEKILESVAEGRA-----LMSVKEMAKGITYDDPIK 143
Query: 625 NYTDKSAQNLASRNLKHERFQSL---------------SFPHTKEMMKIFH--KKFGLHN 667
L+ +HER + SF K I KK G+H+
Sbjct: 144 TSWTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHH 203
Query: 668 FRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPA---CVSPGVTVVISPLRS---LIV 721
Q++ I L G D + TG GK+L + LP C+ + S LI+
Sbjct: 204 PTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLII 263
Query: 722 DQVQKLTS-----LDIPATYLTGDKTDSEATNIYLQ-LSKKDPIIKLLYVTPEKICASNR 775
++L L+ L D + + + +S K+ + + + + R
Sbjct: 264 CPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGR 323
Query: 776 LISTLENLYERKLLARFV-IDEAHCVSQWGH--DFRQDYKRMNMLRQKFPSVPVMALTAT 832
L+ L+ + R++ +DEA + G D R + RQ + +AT
Sbjct: 324 LMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYFKGQRQ------TLLFSAT 377
Query: 833 ANPRVQKDILTQLKILRPQVFSM----SFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPY 888
++Q + +++P ++ + + ++ K+ K+ + LE ++K P
Sbjct: 378 MPKKIQN--FAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAKMVY-LLECLQKTPP- 433
Query: 889 DSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIA 948
+I+ + + D + + L G+ A+A H G R + + + + V+ AT
Sbjct: 434 -PVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAF-REGKKDVLVATDV 491
Query: 949 FGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDG 984
G+D P ++ VI+ +P+ +E Y GR GR G
Sbjct: 492 ASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSG 527
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapiens]
Length = 783
Score = 57.0 bits (136), Expect = 1e-07
Identities = 35/112 (31%), Positives = 55/112 (49%), Gaps = 6/112 (5%)
Query: 892 IIYCLSRRECDTMADT--LQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAF 949
II+C +++E ++ +++D A + H + R E+ K V+ AT
Sbjct: 442 IIFCETKKEAQELSQNSAIKQD---AQSLHGDIPQKQR-EITLKGFRNGSFGVLVATNVA 497
Query: 950 GMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRL 1001
G+D P+V VI +S PK VE Y SGR GR G C+ FY + + +L
Sbjct: 498 ARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQL 549
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 55.8 bits (133), Expect = 3e-07
Identities = 72/356 (20%), Positives = 143/356 (40%), Gaps = 37/356 (10%)
Query: 663 FGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPA--CVSPGV----TVVISPL 716
+G Q AI + G D +G GK+ + + C+ V ++++P
Sbjct: 56 YGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPT 115
Query: 717 RSLIVDQVQKLTSLDIPATYLTGDKTDSEA------TNIYLQLSKKDPIIKLLYVTPEKI 770
R L V Q+QK GD + + TN+ + K D ++ TP ++
Sbjct: 116 RELAV-QIQK-------GLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRV 167
Query: 771 CASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALT 830
R S + + V+DEA + G F++ ++ R P+ V+ ++
Sbjct: 168 FDMIRRRSL-----RTRAIKMLVLDEADEMLNKG--FKEQI--YDVYRYLPPATQVVLIS 218
Query: 831 ATANPRV----QKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHH 886
AT + K + ++IL V +K + + + ++ FD L +
Sbjct: 219 ATLPHEILEMTNKFMTDPIRIL---VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTL 275
Query: 887 PYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICAT 946
+I+C ++R+ D + + ++ + H + R+ + +++ +V+ +T
Sbjct: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEF-RSGASRVLIST 334
Query: 947 IAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLK 1002
+ G+D P V +I+ LP + E Y GR+GR G + F D+ L+
Sbjct: 335 DVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILR 390
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 55.5 bits (132), Expect = 4e-07
Identities = 76/352 (21%), Positives = 136/352 (38%), Gaps = 26/352 (7%)
Query: 661 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG------VTVVIS 714
++ GL QL I A L G DC TG GK+ + LP +V++
Sbjct: 18 RQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLT 77
Query: 715 PLRSLIVDQVQKLTSLDIP-----ATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEK 769
P R L ++ L P + G ++A L+LS+K ++ TP +
Sbjct: 78 PTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQA----LELSRKPHVV---IATPGR 130
Query: 770 ICASNRLISTLENLYERKLLARFVIDEAHCVSQWG-HDFRQDYKRMNMLRQKFPSVPVMA 828
+ R N + K + V+DEA + + G DF D + + + +
Sbjct: 131 LADHLRS----SNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLFS 186
Query: 829 LTATANPRVQKDILTQLKIL-RPQVFSMSFNRHNLKYYVLPKKPKKVAF-DCLEWIRKHH 886
T T R + + T Q + + + +Y ++P+K K ++ + H
Sbjct: 187 ATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEH 246
Query: 887 PYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICAT 946
S II+ + + C + L++ +A H+ + R K+ +++ AT
Sbjct: 247 EDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKF-KSSIYRILIAT 305
Query: 947 IAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDV 998
G+D P V+ VI+ + P + Y GR R G + T +D+
Sbjct: 306 DVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI 357
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 54.7 bits (130), Expect = 6e-07
Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
Query: 892 IIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGM 951
II+C +++ MA A H ++ S R E+ K + +V+ AT
Sbjct: 393 IIFCETKKNVTEMAMN-PHIKQNAQCLHGDIAQSQR-EITLKGFREGSFKVLVATNVAAR 450
Query: 952 GIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFY 993
G+D P+V VI +S P+ VE Y SGR GR G C+ FY
Sbjct: 451 GLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFY 492
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 53.9 bits (128), Expect = 1e-06
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 9/128 (7%)
Query: 1286 SEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYF---------ASKTRNERKR 1336
S +S + SS S SSS G S+++ +PV A K R
Sbjct: 2535 SSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR 2594
Query: 1337 KKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKL 1396
P + KRR ++SS S + S++ SS + SSS SSS+S +S ++S + +K
Sbjct: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654
Query: 1397 GIMAPPKP 1404
G A PKP
Sbjct: 2655 GPQALPKP 2662
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 53.5 bits (127), Expect = 1e-06
Identities = 78/347 (22%), Positives = 131/347 (37%), Gaps = 28/347 (8%)
Query: 663 FGLHNFRTNQLEAINAALLGEDCFILMPTGGGK------SLCYQLPACVSPGVTVVISPL 716
+G Q AI + G D +G GK S+ QL +V++P
Sbjct: 51 YGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPT 110
Query: 717 RSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICAS-NR 775
R L Q+QK+ GD + + ++ + KL P + + R
Sbjct: 111 REL-AQQIQKVI-------LALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGR 162
Query: 776 LISTLENLY-ERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATAN 834
+ L Y K + FV+DEA + G Q Y+ L S+ V+ L+AT
Sbjct: 163 VFDMLNRRYLSPKWIKMFVLDEADEMLSRGFK-DQIYEIFQKLNT---SIQVVLLSATMP 218
Query: 835 PRV----QKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDS 890
V +K + ++IL V +K + + + ++ D L + +
Sbjct: 219 TDVLEVTKKFMRDPIRIL---VKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQ 275
Query: 891 GIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFG 950
+I+ +RR+ D + + + A H + RD + +++ +V+ T
Sbjct: 276 AVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREF-RSGSSRVLITTDLLA 334
Query: 951 MGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHD 997
GID V VI+ LP + E Y GR GR G + F T D
Sbjct: 335 RGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEED 381
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 52.0 bits (123), Expect = 4e-06
Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 892 IIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGM 951
+++ +++ D++ D L +G A + H S R+E ++ ++ AT
Sbjct: 445 LVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQF-RSGKSPILVATAVAAR 503
Query: 952 GIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLI 1005
G+D +V+ VI+ LP +E Y GR GR G + F+ ++ K L+
Sbjct: 504 GLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLL 557
>gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo
sapiens]
Length = 824
Score = 52.0 bits (123), Expect = 4e-06
Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 51/342 (14%)
Query: 672 QLEAINAALLGEDCFILMPTGGGKSLCYQ---LPACVSPGVT---VVISPLRSLIVDQVQ 725
QL+AI G D + +G GK+ + L + V ++ ++++P R + V
Sbjct: 89 QLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHS 148
Query: 726 KLTSLDIP-----------ATYLTGDKTDSEATNIYL-QLSKKDPIIKLLYVTPEKICAS 773
+T++ I T L+ DKT + +I + + +I+L Y+ P I
Sbjct: 149 VITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSI--- 205
Query: 774 NRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATA 833
RL F++DEA + + G F++ ++N + P+ M +
Sbjct: 206 -RL---------------FILDEADKLLEEG-SFQE---QINWIYSSLPASKQMLAVSAT 245
Query: 834 NPRVQKDILTQ---------LKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRK 884
P + LT+ L P + + + Y L K + L+ +
Sbjct: 246 YPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFS 305
Query: 885 HHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVIC 944
P++ +++ +AD L G A ++ + R + K + C+V+
Sbjct: 306 RIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAK-LKHFHCRVLI 364
Query: 945 ATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEI 986
+T GID V V++ +P E Y GRAGR G +
Sbjct: 365 STDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTL 406
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo
sapiens]
Length = 660
Score = 52.0 bits (123), Expect = 4e-06
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 892 IIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGM 951
+++ +++ D++ D L +G A + H S R+E ++ ++ AT
Sbjct: 443 LVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQF-RSGKSPILVATAVAAR 501
Query: 952 GIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLI 1005
G+D +VR VI+ LP +E Y GR GR G + F+ ++ K L+
Sbjct: 502 GLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLL 555
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Homo
sapiens]
Length = 660
Score = 52.0 bits (123), Expect = 4e-06
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 892 IIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGM 951
+++ +++ D++ D L +G A + H S R+E ++ ++ AT
Sbjct: 443 LVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQF-RSGKSPILVATAVAAR 501
Query: 952 GIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLI 1005
G+D +VR VI+ LP +E Y GR GR G + F+ ++ K L+
Sbjct: 502 GLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLL 555
>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
sapiens]
Length = 427
Score = 52.0 bits (123), Expect = 4e-06
Identities = 77/328 (23%), Positives = 138/328 (42%), Gaps = 32/328 (9%)
Query: 672 QLEAINAALLGEDCFILMPTGGGKSLCYQLPAC-----VSPGVTVVISPLRSLIVDQVQK 726
Q E I A+LG D +G GK+ + L V+ VTV++ + Q+ K
Sbjct: 71 QHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCHTRELAFQISK 130
Query: 727 LTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIK-----LLYVTPEKICASNRLISTLE 781
+ + Y+ K L + K + ++K ++ TP +I A R S
Sbjct: 131 --EYERFSKYMPSVKVSVFFGG--LSIKKDEEVLKKNCPHVVVGTPGRILALVRNRS--- 183
Query: 782 NLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATAN--PRVQK 839
+ K + FV+DE + + D R+D + + L + + T + + P +K
Sbjct: 184 --FSLKNVKHFVLDECDKMLEQ-LDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCRK 240
Query: 840 DILTQLKILRPQVFSMSFNRHNLK-YYVLPKKPKK--VAFDCLEWIRKHHPYDSGIIYCL 896
+ +++ ++ H L+ YYV K +K FD L+ + ++ II+
Sbjct: 241 FMQDPMEVFVDDETKLTL--HGLQQYYVKLKDSEKNRKLFDLLDVLE----FNQVIIFVK 294
Query: 897 SRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKP 956
S + C +A L A+A H G++ R Q++ + +++ AT FG G+D
Sbjct: 295 SVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQR-RILVATNLFGRGMDIE 353
Query: 957 DVRFVIHASLPKSVEGYYQESGRAGRDG 984
V V + +P+ + Y RAGR G
Sbjct: 354 RVNIVFNYDMPEDSDTYLHRVARAGRFG 381
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 51.2 bits (121), Expect = 7e-06
Identities = 77/355 (21%), Positives = 134/355 (37%), Gaps = 34/355 (9%)
Query: 663 FGLHNFRTNQLEAINAALLGEDCFILMPTGGGK------SLCYQLPACVSPGVTVVISPL 716
+G Q AI + G D +G GK S+ Q+ + +V++P
Sbjct: 50 YGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPT 109
Query: 717 RSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICAS-NR 775
R L Q+QK+ GD + + + + KL P I + R
Sbjct: 110 REL-AQQIQKVVMA-------LGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 161
Query: 776 LISTLENLY-ERKLLARFVIDEA-HCVSQWGHDFRQD-YKRMNMLRQKFPSVPVMALTAT 832
+ L Y K + FV+DEA +S+ D D ++++N Q V+ L+AT
Sbjct: 162 VFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQ------VVLLSAT 215
Query: 833 ANPRVQKDILTQLKI-----LRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHP 887
+ D+L K +R V ++ + + + ++ D L + +
Sbjct: 216 ----MPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLT 271
Query: 888 YDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATI 947
+I+ +RR+ D + + + A H + RD + +++ +V+ T
Sbjct: 272 ITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREF-RSGSSRVLITTD 330
Query: 948 AFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLK 1002
GID V VI+ LP + E Y GR GR G + T D L+
Sbjct: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLR 385
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,951,315
Number of Sequences: 37866
Number of extensions: 2468662
Number of successful extensions: 9018
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 165
Number of HSP's that attempted gapping in prelim test: 8035
Number of HSP's gapped (non-prelim): 781
length of query: 1417
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1302
effective length of database: 13,892,928
effective search space: 18088592256
effective search space used: 18088592256
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.