Guide to the Human Genome
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Search of human proteins with 4557353

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557353 branched chain keto acid dehydrogenase E1 beta
precursor [Homo sapiens]
         (392 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557353 branched chain keto acid dehydrogenase E1 beta precur...   805   0.0  
gi|34101272 branched chain keto acid dehydrogenase E1 beta precu...   805   0.0  
gi|156564403 pyruvate dehydrogenase (lipoamide) beta [Homo sapiens]   183   3e-46
gi|133778974 transketolase-like 2 [Homo sapiens]                       54   3e-07
gi|225637463 transketolase-like 1 isoform c [Homo sapiens]             43   6e-04
gi|225637461 transketolase-like 1 isoform b [Homo sapiens]             43   6e-04
gi|225637459 transketolase-like 1 isoform a [Homo sapiens]             43   6e-04
gi|38788380 dehydrogenase E1 and transketolase domain containing...    39   0.011
gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase (li...    37   0.031
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ...    34   0.26 
gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens]         32   0.76 
gi|119395764 NLR family, pyrin domain containing 3 isoform a [Ho...    31   2.2  
gi|188536116 NLR family, pyrin domain containing 3 isoform c [Ho...    31   2.2  
gi|188536002 NLR family, pyrin domain containing 3 isoform d [Ho...    31   2.2  
gi|34878693 NLR family, pyrin domain containing 3 isoform a [Hom...    31   2.2  
gi|34878690 NLR family, pyrin domain containing 3 isoform b [Hom...    31   2.2  
gi|7705915 tubulin, epsilon 1 [Homo sapiens]                           30   4.9  
gi|23308587 N-acetylglutamate synthase [Homo sapiens]                  29   8.4  

>gi|4557353 branched chain keto acid dehydrogenase E1 beta precursor
           [Homo sapiens]
          Length = 392

 Score =  805 bits (2078), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP 60
           MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
Sbjct: 1   MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP 60

Query: 61  EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF 120
           EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
Sbjct: 61  EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF 120

Query: 121 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL 180
           NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
Sbjct: 121 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL 180

Query: 181 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP 240
           TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
Sbjct: 181 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP 240

Query: 241 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE 300
           KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
Sbjct: 241 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE 300

Query: 301 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV 360
           VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
Sbjct: 301 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV 360

Query: 361 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 392
           CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
Sbjct: 361 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 392


>gi|34101272 branched chain keto acid dehydrogenase E1 beta
           precursor [Homo sapiens]
          Length = 392

 Score =  805 bits (2078), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP 60
           MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
Sbjct: 1   MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP 60

Query: 61  EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF 120
           EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
Sbjct: 61  EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF 120

Query: 121 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL 180
           NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
Sbjct: 121 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL 180

Query: 181 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP 240
           TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
Sbjct: 181 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP 240

Query: 241 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE 300
           KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
Sbjct: 241 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE 300

Query: 301 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV 360
           VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
Sbjct: 301 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV 360

Query: 361 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 392
           CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
Sbjct: 361 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY 392


>gi|156564403 pyruvate dehydrogenase (lipoamide) beta [Homo sapiens]
          Length = 359

 Score =  183 bits (464), Expect = 3e-46
 Identities = 114/324 (35%), Positives = 172/324 (53%), Gaps = 11/324 (3%)

Query: 76  SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
           ++   +D  L +D    + GE+VA + G ++ + GL  KYG  R+ +TP+ E G  G  +
Sbjct: 38  AINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAV 97

Query: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
           G A+ G   I E    ++   A DQ++N AAK  Y SG L     +  R P G     A 
Sbjct: 98  GAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGL-QPVPIVFRGPNGASAGVAA 156

Query: 195 YHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAAE---EV 251
            HSQ   A++ HCPG+KVV P +   AKGL+ S I D NP +  E +++Y    E   E 
Sbjct: 157 QHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEA 216

Query: 252 PIEPYNIPLSQAEVIQEGSDVTLVAWGTQV-HVIREVASMAKEKLGVSCEVIDLRTIIPW 310
             + + IP+ +A++ ++G+ +T+V+    V H +   A ++KE  GV CEVI++RTI P 
Sbjct: 217 QSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKE--GVECEVINMRTIRPM 274

Query: 311 DVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQE-ECFLNLEAPISRVCGYDTPFPH 369
           D++TI  SV+KT  L+         G  +EI + + E   F  L+AP  RV G D P P+
Sbjct: 275 DMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPY 334

Query: 370 --IFEPFYIPDKWKCYDALRKMIN 391
             I E   IP       A++K +N
Sbjct: 335 AKILEDNSIPQVKDIIFAIKKTLN 358


>gi|133778974 transketolase-like 2 [Homo sapiens]
          Length = 626

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 67/272 (24%), Positives = 101/272 (37%), Gaps = 32/272 (11%)

Query: 86  AKDPTAVIFGEDV--AFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATA 143
           A +   V+ G+ +   F  +FR       K   +R     + EQ +V   +G A  G T 
Sbjct: 335 ANERVIVLSGDTMNSTFSEIFR-------KEHPERFIECIIAEQNMVSVALGCATRGRTI 387

Query: 144 IAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAF 203
                FA +   AFDQ+   A      +    +CG  T          G    +    A 
Sbjct: 388 AFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVSTGED-------GVSQMALEDLAM 440

Query: 204 FAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFF----EPKILYRAAAEEVPIEPYNIP 259
           F   P   V  P      +  +      K  C       E  ++Y       P E  N  
Sbjct: 441 FRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPETAVIY------TPQE--NFE 492

Query: 260 LSQAEVIQEGSD--VTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICK 317
           + QA+V++ G +  VT++  G  +H   E A    ++ G+S  VID  TI P D  TI  
Sbjct: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQ-GISVRVIDPFTIKPLDAATIIS 551

Query: 318 SVIKT-GRLLISHEAPLTGGFASEISSTVQEE 348
           S   T GR++   +    GG    + + V  E
Sbjct: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSRE 583


>gi|225637463 transketolase-like 1 isoform c [Homo sapiens]
          Length = 540

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 31/240 (12%)

Query: 117 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 176
           +R     + EQ +V   +G A  G T      FA ++  AFD I         R G L  
Sbjct: 275 ERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHI---------RIGGLAE 325

Query: 177 CGSLTIRSPWGC-VGH-GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNP 234
                I S  G  VG  GA   +    A F   P   +  P      +  +      K  
Sbjct: 326 SNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGM 385

Query: 235 CIFF----EPKILYRAAAEEVPIEPYNIPLSQAEVIQE--GSDVTLVAWGTQVHVIREVA 288
           C       E  ++Y       P E + I   QA+V++      VT++  G  V+   E  
Sbjct: 386 CFIRTTRPETMVIY------TPQERFEI--GQAKVLRHCVSDKVTVIGAGITVY---EAL 434

Query: 289 SMAKE--KLGVSCEVIDLRTIIPWDVDTICKSVIKT-GRLLISHEAPLTGGFASEISSTV 345
           + A E  K  +   VIDL TI P DV TI  S   T GR++   +    GG    + + V
Sbjct: 435 AAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAV 494


>gi|225637461 transketolase-like 1 isoform b [Homo sapiens]
          Length = 590

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 31/240 (12%)

Query: 117 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 176
           +R     + EQ +V   +G A  G T      FA ++  AFD I         R G L  
Sbjct: 325 ERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHI---------RIGGLAE 375

Query: 177 CGSLTIRSPWGC-VGH-GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNP 234
                I S  G  VG  GA   +    A F   P   +  P      +  +      K  
Sbjct: 376 SNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGM 435

Query: 235 CIFF----EPKILYRAAAEEVPIEPYNIPLSQAEVIQE--GSDVTLVAWGTQVHVIREVA 288
           C       E  ++Y       P E + I   QA+V++      VT++  G  V+   E  
Sbjct: 436 CFIRTTRPETMVIY------TPQERFEI--GQAKVLRHCVSDKVTVIGAGITVY---EAL 484

Query: 289 SMAKE--KLGVSCEVIDLRTIIPWDVDTICKSVIKT-GRLLISHEAPLTGGFASEISSTV 345
           + A E  K  +   VIDL TI P DV TI  S   T GR++   +    GG    + + V
Sbjct: 485 AAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAV 544


>gi|225637459 transketolase-like 1 isoform a [Homo sapiens]
          Length = 596

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 31/240 (12%)

Query: 117 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 176
           +R     + EQ +V   +G A  G T      FA ++  AFD I         R G L  
Sbjct: 331 ERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHI---------RIGGLAE 381

Query: 177 CGSLTIRSPWGC-VGH-GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNP 234
                I S  G  VG  GA   +    A F   P   +  P      +  +      K  
Sbjct: 382 SNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGM 441

Query: 235 CIFF----EPKILYRAAAEEVPIEPYNIPLSQAEVIQE--GSDVTLVAWGTQVHVIREVA 288
           C       E  ++Y       P E + I   QA+V++      VT++  G  V+   E  
Sbjct: 442 CFIRTTRPETMVIY------TPQERFEI--GQAKVLRHCVSDKVTVIGAGITVY---EAL 490

Query: 289 SMAKE--KLGVSCEVIDLRTIIPWDVDTICKSVIKT-GRLLISHEAPLTGGFASEISSTV 345
           + A E  K  +   VIDL TI P DV TI  S   T GR++   +    GG    + + V
Sbjct: 491 AAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAV 550


>gi|38788380 dehydrogenase E1 and transketolase domain containing 1
           [Homo sapiens]
          Length = 919

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 62/266 (23%), Positives = 110/266 (41%), Gaps = 40/266 (15%)

Query: 119 VFNTPLCEQGIVGFGIGIAVTGATAIA--EIQFADYIFPA---FDQIVNEA-AKYRYRSG 172
           V N+PL E+ ++GF  G+++     +   E QF D+   A   FD  ++   AK+  +SG
Sbjct: 633 VSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSG 692

Query: 173 DLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIK-----------VVIPRSPFQA 221
                  + I  P G  G G  + S   E F   C   +           VV P +P Q 
Sbjct: 693 -------IVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNMFVVHPTTPAQY 745

Query: 222 KGLLLSCI--EDKNPCIFFEPKILYRAAA------EEVPIEPYNIPLSQAEVIQEGSDVT 273
             LL   +    + P I   PK+L R  A      E  P   +N  +  + V  +     
Sbjct: 746 FHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVDPKKVKTL 805

Query: 274 LVAWGTQVH-VIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRL---LISH 329
           +   G   + ++++  S+  +K   +  +I +  + P+ +D++ + + K   +   + S 
Sbjct: 806 VFCSGKHFYSLVKQRESLGAKKHDFA--IIRVEELCPFPLDSLQQEMSKYKHVKDHIWSQ 863

Query: 330 EAPLTGGFASEISSTVQEE--CFLNL 353
           E P   G  S +S   +++  C L L
Sbjct: 864 EEPQNMGPWSFVSPRFEKQLACKLRL 889


>gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase
           (lipoamide) isoform 1 precursor [Homo sapiens]
          Length = 1023

 Score = 37.0 bits (84), Expect = 0.031
 Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 13/103 (12%)

Query: 119 VFNTPLCEQGIVGFGIGIAVTGATAIA--EIQFADYIFPA---FDQIVNEA-AKYRYRSG 172
           V N+ L E G++GF +G A+    A+   E QF D+   A    DQ +    AK+  ++G
Sbjct: 715 VCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNG 774

Query: 173 DLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIP 215
                  + +  P G  G G  + S  PE F   C     V+P
Sbjct: 775 -------IVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLP 810


>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
           subunit [Homo sapiens]
          Length = 1091

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 22/123 (17%)

Query: 244 YRAAAEEVPIE-PYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVS---- 298
           YR AAE++P    Y+IP S   V +      +V   T + ++ E  S     +G+     
Sbjct: 770 YRRAAEQIPGSFVYSIPFSTGPVNKSN----VVTASTSIQLLDERKSPVVAAVGIQMKLE 825

Query: 299 ------------CEVIDLRTIIPWDVDTI-CKSVIKTGRLLISHEAPLTGGFASEISSTV 345
                       C  +D +  I  D +T+ C  +   G +L+S +   TG F  EI   V
Sbjct: 826 FFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAV 885

Query: 346 QEE 348
             +
Sbjct: 886 MNK 888


>gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens]
          Length = 589

 Score = 32.3 bits (72), Expect = 0.76
 Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 14/73 (19%)

Query: 6   AAAGWLLRLRAAGAEGHWRR---LPGAGLA---------RGFLHPAATVEDAAQRRQVAH 53
           ++AGW  ++ A+G  G W R   LPGA             GFL P    E  + R   + 
Sbjct: 133 SSAGW--KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSS 190

Query: 54  FTFQPDPEPREYG 66
           F  +  P PR  G
Sbjct: 191 FVLRGSPAPRADG 203


>gi|119395764 NLR family, pyrin domain containing 3 isoform a [Homo
           sapiens]
          Length = 1036

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 192 GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCI 236
           G LY  +    F+ HC  + +V  RS      L++SC  D NP I
Sbjct: 246 GTLYQDRFDYLFYIHCREVSLVTQRS---LGDLIMSCCPDPNPPI 287


>gi|188536116 NLR family, pyrin domain containing 3 isoform c [Homo
           sapiens]
          Length = 979

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 192 GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCI 236
           G LY  +    F+ HC  + +V  RS      L++SC  D NP I
Sbjct: 246 GTLYQDRFDYLFYIHCREVSLVTQRS---LGDLIMSCCPDPNPPI 287


>gi|188536002 NLR family, pyrin domain containing 3 isoform d [Homo
           sapiens]
          Length = 979

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 192 GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCI 236
           G LY  +    F+ HC  + +V  RS      L++SC  D NP I
Sbjct: 246 GTLYQDRFDYLFYIHCREVSLVTQRS---LGDLIMSCCPDPNPPI 287


>gi|34878693 NLR family, pyrin domain containing 3 isoform a [Homo
           sapiens]
          Length = 1036

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 192 GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCI 236
           G LY  +    F+ HC  + +V  RS      L++SC  D NP I
Sbjct: 246 GTLYQDRFDYLFYIHCREVSLVTQRS---LGDLIMSCCPDPNPPI 287


>gi|34878690 NLR family, pyrin domain containing 3 isoform b [Homo
           sapiens]
          Length = 922

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 192 GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCI 236
           G LY  +    F+ HC  + +V  RS      L++SC  D NP I
Sbjct: 246 GTLYQDRFDYLFYIHCREVSLVTQRS---LGDLIMSCCPDPNPPI 287


>gi|7705915 tubulin, epsilon 1 [Homo sapiens]
          Length = 475

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 44/201 (21%), Positives = 80/201 (39%), Gaps = 34/201 (16%)

Query: 189 VGH---GALYHSQSPEAF---FAHCPGIK---VVIPRSPFQAKGL---LLSCIEDKNPCI 236
           VGH   G+LY  Q  E F     HC  ++   ++         GL   LL  +ED+ P +
Sbjct: 111 VGHKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEV 170

Query: 237 FFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKE-KL 295
           +     +Y +  ++V   PYN  L+  E+ +    V  +   +   +I ++  M    KL
Sbjct: 171 YRFVTSIYPSGEDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKL 230

Query: 296 GVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAP------LTGGFASEISSTVQEEC 349
           G + +   L T               +G L   H+ P      +       ++S+ + E 
Sbjct: 231 GTTVKPKSLVT-------------SSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEG 277

Query: 350 FLNLEAPISRVCGYDTPFPHI 370
            LN++  ++ +     PFP +
Sbjct: 278 SLNMD--LNEISMNLVPFPQL 296


>gi|23308587 N-acetylglutamate synthase [Homo sapiens]
          Length = 534

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 7/65 (10%)

Query: 1  MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP 60
          MAVV  AA    RLR  G  G  RRL      R            +  R+++    QP P
Sbjct: 6  MAVVLRAAAVAPRLRGRGGTGGARRLSCGARRR-------AARGTSPGRRLSTAWSQPQP 58

Query: 61 EPREY 65
           P EY
Sbjct: 59 PPEEY 63


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,169,575
Number of Sequences: 37866
Number of extensions: 674344
Number of successful extensions: 1380
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1374
Number of HSP's gapped (non-prelim): 18
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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