Search of human proteins with 4557345

Search of human proteins with 4557345

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo
sapiens]
         (371 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]   751   0.0  
gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo sap...   619   e-177
gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]            269   3e-72
gi|32307152 oxytocin receptor [Homo sapiens]                          264   8e-71
gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]            252   4e-67
gi|46391085 G protein-coupled receptor for asthma susceptibility...   143   3e-34
gi|46395496 G protein-coupled receptor for asthma susceptibility...   142   4e-34
gi|4557865 somatostatin receptor 5 [Homo sapiens]                     111   1e-24
gi|28875799 cholecystokinin B receptor [Homo sapiens]                 104   1e-22
gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Ho...   101   1e-21
gi|40385873 G protein-coupled receptor 150 [Homo sapiens]              97   3e-20
gi|4503905 galanin receptor 2 [Homo sapiens]                           96   4e-20
gi|167000885 galanin receptor 1 [Homo sapiens]                         96   7e-20
gi|149944554 somatostatin receptor 4 [Homo sapiens]                    94   2e-19
gi|4557859 somatostatin receptor 2 [Homo sapiens]                      89   5e-18
gi|9506745 urotensin 2 receptor [Homo sapiens]                         89   8e-18
gi|222080109 orexin receptor 2 [Homo sapiens]                          88   1e-17
gi|4557857 somatostatin receptor 1 [Homo sapiens]                      87   2e-17
gi|4758474 G protein-coupled receptor 10 [Homo sapiens]                87   3e-17
gi|63477962 opioid receptor, delta 1 [Homo sapiens]                    86   4e-17
gi|4503907 galanin receptor 3 [Homo sapiens]                           86   5e-17
gi|4505513 opiate receptor-like 1 [Homo sapiens]                       86   7e-17
gi|33286424 opiate receptor-like 1 [Homo sapiens]                      86   7e-17
gi|222080095 orexin receptor 1 [Homo sapiens]                          82   6e-16
gi|4885057 apelin receptor [Homo sapiens]                              82   8e-16
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]       81   1e-15
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]        81   1e-15
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]      81   1e-15
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]      81   1e-15
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]      81   1e-15

>gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]
          Length = 371

 Score =  751 bits (1939), Expect = 0.0
 Identities = 371/371 (100%), Positives = 371/371 (100%)

Query: 1   MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA 60
           MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
Sbjct: 1   MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA 60

Query: 61  ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM 120
           ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
Sbjct: 61  ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM 120

Query: 121 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ 180
           VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
Sbjct: 121 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ 180

Query: 181 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP 240
           RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP
Sbjct: 181 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP 240

Query: 241 SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA 300
           SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA
Sbjct: 241 SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA 300

Query: 301 PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTT 360
           PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTT
Sbjct: 301 PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTT 360

Query: 361 ASSSLAKDTSS 371
           ASSSLAKDTSS
Sbjct: 361 ASSSLAKDTSS 371


>gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo
           sapiens]
          Length = 309

 Score =  619 bits (1597), Expect = e-177
 Identities = 304/304 (100%), Positives = 304/304 (100%)

Query: 1   MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA 60
           MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
Sbjct: 1   MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA 60

Query: 61  ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM 120
           ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
Sbjct: 61  ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM 120

Query: 121 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ 180
           VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
Sbjct: 121 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ 180

Query: 181 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP 240
           RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP
Sbjct: 181 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP 240

Query: 241 SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA 300
           SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA
Sbjct: 241 SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA 300

Query: 301 PLEG 304
           PLEG
Sbjct: 301 PLEG 304


>gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]
          Length = 424

 Score =  269 bits (687), Expect = 3e-72
 Identities = 154/333 (46%), Positives = 198/333 (59%), Gaps = 27/333 (8%)

Query: 32  RDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALF 91
           RD  LA+ E+ +L+ V V     N  VL  L + GR+   + +H+F+ HL L DLAVALF
Sbjct: 29  RDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKR--SRMHLFVLHLALTDLAVALF 86

Query: 92  QVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHG 151
           QVLPQL W  T RF+GPD LCRAVKYLQ++ M+AS+YM+LAMTLDR+ A+C P+ + +  
Sbjct: 87  QVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQ- 145

Query: 152 SGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIAL 211
            G      +   W  + + SLPQ+FIF+ R V  GSGV DCWA F  PWG R Y+TW  L
Sbjct: 146 PGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTL 205

Query: 212 MVFVAPTLGIAACQVLIFREIHASL-VPGPSERPGGRRRGRRT--------------GSP 256
            +FV P   + AC  LI  EI  +L V   + R GG   G RT              G P
Sbjct: 206 AIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGG--GWRTWDRPSPSTLAATTRGLP 263

Query: 257 GEGAHV---SAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAP---FVLL 310
              + +   S A  +TV+MT VIV+ Y+ CWAPFF VQ+W+ WD  AP E +    F + 
Sbjct: 264 SRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTIS 323

Query: 311 MLLASLNSCTNPWIYASFSSS-VSSELRSLLCC 342
           MLL +LNSC NPWIY  F+S  +   LR L CC
Sbjct: 324 MLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACC 356


>gi|32307152 oxytocin receptor [Homo sapiens]
          Length = 389

 Score =  264 bits (675), Expect = 8e-71
 Identities = 159/378 (42%), Positives = 216/378 (57%), Gaps = 37/378 (9%)

Query: 4   ASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALA 63
           A+  SA P     P    N +   P   R+  LAR E+A+L ++ +     N  VL AL 
Sbjct: 13  AANASAAP-----PGAEGNRTAGPP--RRNEALARVEVAVLCLILLLALSGNACVLLAL- 64

Query: 64  RRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGM 123
           R  R+ H + +  F+ HL +ADL VA+FQVLPQL W  T RF GPD LCR VKYLQ+VGM
Sbjct: 65  RTTRQKH-SRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGM 123

Query: 124 YASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNV 183
           +AS+Y++L M+LDR  AIC+P+ + R  +       VL  W   L+ S PQ+ IF+ R V
Sbjct: 124 FASTYLLLLMSLDRCLAICQPLRSLRRRTD---RLAVLATWLGCLVASAPQVHIFSLREV 180

Query: 184 EGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL------- 236
               GV DCWA F +PWG + Y+TWI L V++ P + +AAC  LI  +I  +L       
Sbjct: 181 --ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAA 238

Query: 237 -----VPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQ 291
                  G +   GGR    R  S      +S A  +TV+MT +IV+ +++CW PFF VQ
Sbjct: 239 AAAEAPEGAAAGDGGRVALARVSSV---KLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQ 295

Query: 292 LWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSEL-RSLLCCA----RGR 346
           +W+ WD  AP E + F+++MLLASLNSC NPWIY  F+  +  EL +  LCC+    +GR
Sbjct: 296 MWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGR 355

Query: 347 TPPSLGPQDESCTTASSS 364
               LG    S  + SSS
Sbjct: 356 ---RLGETSASKKSNSSS 370


>gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]
          Length = 418

 Score =  252 bits (643), Expect = 4e-67
 Identities = 136/340 (40%), Positives = 187/340 (55%), Gaps = 40/340 (11%)

Query: 28  PLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLA 87
           P D R+  LA+ E+A+L++ F    L N  VL AL R  R+   + +H+FI HL LADLA
Sbjct: 42  PRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKT--SRMHLFIRHLSLADLA 99

Query: 88  VALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLA 147
           VA FQVLPQ+ W  T RFRGPD LCR VK+LQ+ GM+AS+YM++ MT DR+ A+C P+  
Sbjct: 100 VAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKT 159

Query: 148 YRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVT 207
            +  +       +  AW  S +LS PQ F+F+   V   +   DCWA F +PWG R YVT
Sbjct: 160 LQQPARRS-RLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVT 218

Query: 208 WIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAH------ 261
           W+   +FVAP + +  C   I   I  ++            RG+      +GA       
Sbjct: 219 WMTGGIFVAPVVILGTCYGFICYNIWCNV------------RGKTASRQSKGAEQAGVAF 266

Query: 262 ---------------VSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA---PLE 303
                          +S A  +TV+MT VIV  Y++CWAPFF++Q+W+ WDP +     E
Sbjct: 267 QKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESE 326

Query: 304 GAPFVLLMLLASLNSCTNPWIYASFSSSVSSE-LRSLLCC 342
                +  LL SLNSC NPWIY  FS  +  + ++S  CC
Sbjct: 327 NPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCC 366


>gi|46391085 G protein-coupled receptor for asthma susceptibility
           isoform B [Homo sapiens]
          Length = 377

 Score =  143 bits (360), Expect = 3e-34
 Identities = 92/326 (28%), Positives = 163/326 (50%), Gaps = 23/326 (7%)

Query: 40  ELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAW 99
           +L  L ++FV   + N +VL +  RR ++        F+  L + D    L  +L  + W
Sbjct: 52  QLITLWVLFVFTIVGNSVVLFSTWRRKKKSRMT---FFVTQLAITDSFTGLVNILTDINW 108

Query: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
           + T  F  PD +CR V+YLQ+V +YAS+Y+++++++DR+ AI  PM   +    A     
Sbjct: 109 RFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQA--RVL 166

Query: 160 VLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTL 219
           +++AW+ S L S+P L IF +R +  G     CWA + +      Y+T +A +V+  P  
Sbjct: 167 IVIAWSLSFLFSIPTLIIFGKRTLSNGE--VQCWALWPDDSYWTPYMTIVAFLVYFIPLT 224

Query: 220 GIAACQVLIFREI------HASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMT 273
            I+    ++ R I      + +++   S+       G+   S   G  +S A  K ++ +
Sbjct: 225 IISIMYGIVIRTIWIKSKTYETVISNCSD-------GKLCSSYNRGL-ISKAKIKAIKYS 276

Query: 274 LVIVVVYVLCWAPFFLVQLWAAWD--PEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSS 331
           ++I++ ++ CW+P+FL  +   ++  P+        V++  L +LNS  NP IY  FSSS
Sbjct: 277 IIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSS 336

Query: 332 VSSELRSLLCCARGRTPPSLGPQDES 357
           +S   R +           L PQ E+
Sbjct: 337 ISFPCRVIRLRQLQEAALMLCPQREN 362


>gi|46395496 G protein-coupled receptor for asthma susceptibility
           isoform A [Homo sapiens]
          Length = 371

 Score =  142 bits (359), Expect = 4e-34
 Identities = 88/306 (28%), Positives = 157/306 (51%), Gaps = 23/306 (7%)

Query: 40  ELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAW 99
           +L  L ++FV   + N +VL +  RR ++        F+  L + D    L  +L  + W
Sbjct: 52  QLITLWVLFVFTIVGNSVVLFSTWRRKKKSRMT---FFVTQLAITDSFTGLVNILTDINW 108

Query: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
           + T  F  PD +CR V+YLQ+V +YAS+Y+++++++DR+ AI  PM   +    A     
Sbjct: 109 RFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQA--RVL 166

Query: 160 VLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTL 219
           +++AW+ S L S+P L IF +R +  G     CWA + +      Y+T +A +V+  P  
Sbjct: 167 IVIAWSLSFLFSIPTLIIFGKRTLSNGE--VQCWALWPDDSYWTPYMTIVAFLVYFIPLT 224

Query: 220 GIAACQVLIFREI------HASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMT 273
            I+    ++ R I      + +++   S+       G+   S   G  +S A  K ++ +
Sbjct: 225 IISIMYGIVIRTIWIKSKTYETVISNCSD-------GKLCSSYNRGL-ISKAKIKAIKYS 276

Query: 274 LVIVVVYVLCWAPFFLVQLWAAWD--PEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSS 331
           ++I++ ++ CW+P+FL  +   ++  P+        V++  L +LNS  NP IY  FSSS
Sbjct: 277 IIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSS 336

Query: 332 VSSELR 337
           +S   R
Sbjct: 337 ISFPCR 342


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score =  111 bits (277), Expect = 1e-24
 Identities = 106/349 (30%), Positives = 159/349 (45%), Gaps = 57/349 (16%)

Query: 15  SLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALS----NGLVLAALARRGRRGH 70
           S P   S     R L    P  A A   L+ ++++ V  +    N LV+  + R  +   
Sbjct: 15  SSPGAASGGGDNRTLVGPAPS-AGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMK- 72

Query: 71  WAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFR--GPDALCRAVKYLQMVGMYASSY 128
               +++I +L +AD+   L   LP LA +    F   GP  LCR V  L  V  + S +
Sbjct: 73  -TVTNIYILNLAVADVLYMLG--LPFLATQNAASFWPFGP-VLCRLVMTLDGVNQFTSVF 128

Query: 129 MILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLV------AWAFSLLLSLPQLFIFAQRN 182
            +  M++DR+ A+  P+      S A W RP +       AW  SL +SLP L +FA   
Sbjct: 129 CLTVMSVDRYLAVVHPL------SSARWRRPRVAKLASAAAWVLSLCMSLP-LLVFADVQ 181

Query: 183 VEGGSGVTDCWACFAEP---WGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPG 239
            EGG+    C A + EP   WG   ++ + A++ F AP L I  C +LI  ++ A+ V  
Sbjct: 182 -EGGT----CNASWPEPVGLWGA-VFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGV-- 233

Query: 240 PSERPGG-RRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQL--WAAW 296
              R G  RRR  R               K  RM LV+V+V+  CW PFF V +   A  
Sbjct: 234 ---RVGCVRRRSER---------------KVTRMVLVVVLVFAGCWLPFFTVNIVNLAVA 275

Query: 297 DPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARG 345
            P+ P     +  +++L+  NSC NP +Y   S +     + +LC  +G
Sbjct: 276 LPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKG 324


>gi|28875799 cholecystokinin B receptor [Homo sapiens]
          Length = 447

 Score =  104 bits (260), Expect = 1e-22
 Identities = 112/423 (26%), Positives = 173/423 (40%), Gaps = 77/423 (18%)

Query: 11  PGHPSLPSLP-SNSSQERP----LDTRDPLLARAELALLSIVFVAVALSNGLVLAAL--A 63
           PG P L S    N S E P      TR+  LA   + L +++F+     N L++  L  +
Sbjct: 24  PGAPLLNSSSVGNLSCEPPRIRGAGTRELELA-IRITLYAVIFLMSVGGNMLIIVVLGLS 82

Query: 64  RRGRRGHWAPIHVFIGHLCLADLAVAL----FQVLPQLAWKATDRFRGPDALCRAVKYLQ 119
           RR R       + F+  L ++DL +A+    F +LP L       F     +C+AV YL 
Sbjct: 83  RRLR----TVTNAFLLSLAVSDLLLAVACMPFTLLPNLM----GTFIFGTVICKAVSYLM 134

Query: 120 MVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFA 179
            V +  S+  ++A+ L+R+ AICRP+ A    + +H  R ++  W  S LL +P      
Sbjct: 135 GVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTV 194

Query: 180 QRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL--- 236
            + V  G  V  C   +     R+T+   + L++F  P + +A    LI RE++  L   
Sbjct: 195 VQPV--GPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFD 252

Query: 237 ----------------VPG--------------------------PSERPGGRRRGRRTG 254
                           +PG                          P  RP          
Sbjct: 253 GDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAP 312

Query: 255 SPGEGAHVS----AAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWD---PEAPLEGAPF 307
            PG G+  +     A  + VRM LVIVV++ LCW P +    W A+D       L GAP 
Sbjct: 313 GPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPI 372

Query: 308 VLLMLLASLNSCTNPWIYASFSSSVSSELRSLL--CCAR-GRTPPSLGPQDESCTTASSS 364
             + LL+  ++C NP +Y                 CC R  R  P   P ++  T + +S
Sbjct: 373 SFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIAS 432

Query: 365 LAK 367
           L++
Sbjct: 433 LSR 435


>gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Homo
           sapiens]
          Length = 328

 Score =  101 bits (251), Expect = 1e-21
 Identities = 81/298 (27%), Positives = 137/298 (45%), Gaps = 24/298 (8%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGH-WAPIHVFIGHLCLADLAVALFQVLPQLAW 99
           L LLS  F A  L   L L    ++  +G   + + + + HL LA+L   L  +     W
Sbjct: 45  LFLLSATFNASFL---LKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMW 101

Query: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
             T ++   + LC+ + YL++  MYA ++M++ ++LDR  AI RP LA +  S    +  
Sbjct: 102 NITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRP-LALKSNSKVGQSM- 159

Query: 160 VLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWA------CFAEPWGRRTYVTWIALMV 213
           V +AW  S + + PQL+IF   ++   SG T  ++       F++ W +  Y  +    +
Sbjct: 160 VGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCL 219

Query: 214 FVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMT 273
           F+ P   +  C   I   +   L   P E    + +           ++  A  KT++MT
Sbjct: 220 FIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKN----------NIPRARLKTLKMT 269

Query: 274 LVIVVVYVLCWAPFFLVQLWAAWDPEA--PLEGAPFVLLMLLASLNSCTNPWIYASFS 329
           +     + +CW P++++ +W  +DPE    L         L A LN C +P IY  FS
Sbjct: 270 VAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFS 327


>gi|40385873 G protein-coupled receptor 150 [Homo sapiens]
          Length = 434

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 98/362 (27%), Positives = 145/362 (40%), Gaps = 53/362 (14%)

Query: 34  PLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWA-----PIHVFIGHLCLADLAV 88
           P   R  L  L ++ V     N  VL  L   G  G WA      +   +  L LADL  
Sbjct: 39  PPSRRVRLVFLGVILVVAVAGNTTVLCRLCGGG--GPWAGPKRRKMDFLLVQLALADLYA 96

Query: 89  ALFQVLPQLAWKATDRFRGP--DALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPML 146
                L QLAW+     R    D  CR ++ LQ  G  AS+++++ + L+R RA+  P  
Sbjct: 97  CGGTALSQLAWELLGEPRAATGDLACRFLQLLQASGRGASAHLVVLIALERRRAVRLP-- 154

Query: 147 AYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIF--------------------AQRNVEGG 186
              HG          + W  +LLL+LP  F+                     A       
Sbjct: 155 ---HGRPLPARALAALGWLLALLLALPPAFVVRGDSPSPLPPPPPPTSLQPGAPPAARAW 211

Query: 187 SGVTDCWACFA--EPWGRRTYVTWIALMVFVAP--TLGIAACQVLIFREIHASLVPGPSE 242
            G   C   FA    W  + Y  + A+  FVAP   LG+A   +L     H    P  + 
Sbjct: 212 PGERRCHGIFAPLPRWHLQVYAFYEAVAGFVAPVTVLGVACGHLLSVWWRHRPQAPA-AA 270

Query: 243 RPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWD--PEA 300
            P     GR   +P   A +  A  ++++M+L++ +++V C  P+F  +L AAW   P  
Sbjct: 271 APWSASPGR---APAPSA-LPRAKVQSLKMSLLLALLFVGCELPYFAARLAAAWSSGPAG 326

Query: 301 PLEGAPF-VLLMLLASLNSCTNPWIYASFSS-------SVSSELRSLLCCARGRTPPSLG 352
             EG      L ++A  NS  NP++Y  F +        +   L SL C  +G      G
Sbjct: 327 DWEGEGLSAALRVVAMANSALNPFVYLFFQAGDCRLRRQLRKRLGSLCCAPQGGAEDEEG 386

Query: 353 PQ 354
           P+
Sbjct: 387 PR 388


>gi|4503905 galanin receptor 2 [Homo sapiens]
          Length = 387

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 84/309 (27%), Positives = 138/309 (44%), Gaps = 27/309 (8%)

Query: 43  LLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKAT 102
           L +++F+   + N LVLA L R G+    +  ++FI +L +ADL   L  V  Q      
Sbjct: 31  LFALIFLVGTVGNTLVLAVLLRGGQAV--STTNLFILNLGVADLCFILCCVPFQATIYTL 88

Query: 103 DRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLV 162
           D +     LC+AV +L  + M+ASS+ + A++LDR+ AI  P+ +    +  +    + +
Sbjct: 89  DGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGL 148

Query: 163 AWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIA 222
            W  SLL S P L  + Q  +   + +T C   ++ P  RR       +  ++ P L + 
Sbjct: 149 IWGLSLLFSGPYLSYYRQSQL---ANLTVCHPAWSAP-RRRAMDICTFVFSYLLPVLVLG 204

Query: 223 ACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVL 282
                  R +  ++   P     G RR +R               K  RM L++  ++ L
Sbjct: 205 LTYARTLRYLWRAV--DPVAAGSGARRAKR---------------KVTRMILIVAALFCL 247

Query: 283 CWAPFFLVQLWAAWDPEAPLEGAPF---VLLMLLASLNSCTNPWIYASFSSSVSSELRSL 339
           CW P   + L   W  + PL  A +   +L  L++  NSC NP +YA  S       R++
Sbjct: 248 CWMPHHALIL-CVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTI 306

Query: 340 LCCARGRTP 348
                GR P
Sbjct: 307 CAGLLGRAP 315


>gi|167000885 galanin receptor 1 [Homo sapiens]
          Length = 349

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 82/312 (26%), Positives = 134/312 (42%), Gaps = 38/312 (12%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWK 100
           L +  ++F    L N LV+  LAR       +  ++FI +L +ADLA  LF +  Q    
Sbjct: 37  LVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVY 96

Query: 101 ATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPV 160
           A   +     +C+ + Y   V M  S + + AM++DR+ AI       R  S    +R  
Sbjct: 97  ALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHS----RRSSSLRVSRNA 152

Query: 161 LVA----WAFSLLLSLPQLF---IFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMV 213
           L+     WA S+ ++ P  +   +F  R     S  T CW  + +P  ++ YV    +  
Sbjct: 153 LLGVGCIWALSIAMASPVAYHQGLFHPR----ASNQTFCWEQWPDPRHKKAYVVCTFVFG 208

Query: 214 FVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMT 273
           ++ P L I  C   +   +H  L          +   +++          A+  KT +  
Sbjct: 209 YLLPLLLICFCYAKVLNHLHKKL----------KNMSKKS---------EASKKKTAQTV 249

Query: 274 LVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLM---LLASLNSCTNPWIYASFSS 330
           LV+VVV+ + W P  ++ LWA +    PL  A F+  +    LA  NS  NP IYA  S 
Sbjct: 250 LVVVVVFGISWLPHHIIHLWAEFG-VFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSE 308

Query: 331 SVSSELRSLLCC 342
           +     + +  C
Sbjct: 309 NFRKAYKQVFKC 320


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 83/303 (27%), Positives = 142/303 (46%), Gaps = 32/303 (10%)

Query: 43  LLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQV-LPQLAWKA 101
           + ++V +   + N LV+  + R  +       ++++ +L +AD    LF + +P +A  A
Sbjct: 53  IYALVCLVGLVGNALVIFVILRYAKMK--TATNIYLLNLAVAD---ELFMLSVPFVASSA 107

Query: 102 TDR-FRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLA--YRHGSGAHWNR 158
             R +     LCRAV  +  + M+ S + +  +++DR+ A+  P+ A  YR  S A    
Sbjct: 108 ALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLIN 167

Query: 159 PVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPT 218
             L  W  SLL++LP       R   GG  V  C   +  P     +V +  L+ F+ P 
Sbjct: 168 --LGVWLASLLVTLPIAIFADTRPARGGQAVA-CNLQWPHPAWSAVFVVYTFLLGFLLPV 224

Query: 219 LGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVV 278
           L I  C +LI  ++ A  +     R G ++R R             +  K  R+ L++VV
Sbjct: 225 LAIGLCYLLIVGKMRAVAL-----RAGWQQRRR-------------SEKKITRLVLMVVV 266

Query: 279 VYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRS 338
           V+VLCW PF++VQL   +     L+     + ++L+  NSC NP +Y   S +     + 
Sbjct: 267 VFVLCWMPFYVVQLLNLF--VTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQR 324

Query: 339 LLC 341
           +LC
Sbjct: 325 VLC 327


>gi|4557859 somatostatin receptor 2 [Homo sapiens]
          Length = 369

 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 80/320 (25%), Positives = 145/320 (45%), Gaps = 49/320 (15%)

Query: 42  ALLSIVFVAVAL----SNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQV-LPQ 96
           A+L+ ++  V +     N LV+  + R  +       +++I +L +AD    LF + LP 
Sbjct: 44  AVLTFIYFVVCIIGLCGNTLVIYVILRYAKMK--TITNIYILNLAIAD---ELFMLGLPF 98

Query: 97  LAWK-ATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAH 155
           LA + A   +    A+CR V  +  +  + S + +  M++DR+ A+  P+        A 
Sbjct: 99  LAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPI------KSAK 152

Query: 156 WNRP------VLVAWAFSLLLSLPQLFIFA--QRNVEGGSGVTDCWACFAEPWGRRTYVT 207
           W RP       +  W  SLL+ LP + I+A  + N  G S  T  W   +  W    ++ 
Sbjct: 153 WRRPRTAKMITMAVWGVSLLVILP-IMIYAGLRSNQWGRSSCTINWPGESGAW-YTGFII 210

Query: 208 WIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVA 267
           +  ++ F+ P   I  C + I  ++ +S +     R G  +R +             +  
Sbjct: 211 YTFILGFLVPLTIICLCYLFIIIKVKSSGI-----RVGSSKRKK-------------SEK 252

Query: 268 KTVRMTLVIVVVYVLCWAPFFLVQLWA---AWDPEAPLEGAPFVLLMLLASLNSCTNPWI 324
           K  RM  ++V V++ CW PF++  + +   A  P   L+G  F  +++L   NSC NP +
Sbjct: 253 KVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGM-FDFVVVLTYANSCANPIL 311

Query: 325 YASFSSSVSSELRSLLCCAR 344
           YA  S +     +++LC  +
Sbjct: 312 YAFLSDNFKKSFQNVLCLVK 331


>gi|9506745 urotensin 2 receptor [Homo sapiens]
          Length = 389

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 101/365 (27%), Positives = 160/365 (43%), Gaps = 43/365 (11%)

Query: 3   MASTTSAVPGHPSLPSLPSNSSQERPLD--TRDPLLARAELA-LLSIVFVAVALSNGLVL 59
           +A+T S+VP  P  P+   NSS   P +  + + L+A   +  LLS + V   + N   L
Sbjct: 14  LAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSAMGVVGVVGNAYTL 73

Query: 60  AALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQ 119
               R  R    A ++V++ +L LADL + L  +   +A   T  +   D  CR +  L 
Sbjct: 74  VVTCRSLRAV--ASMYVYVVNLALADL-LYLLSIPFIVATYVTKEWHFGDVGCRVLFGLD 130

Query: 120 MVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFA 179
            + M+AS + +  M+ +R+ A+ RP+   +   G +     L  W  +LLL+LP   + A
Sbjct: 131 FLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKG-YRKLLALGTWLLALLLTLP--VMLA 187

Query: 180 QRNVEGG--SGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLV 237
            R V  G  S     W     P   R Y+T +       P L I      + R    S  
Sbjct: 188 MRLVRRGPKSLCLPAWG----PRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRRS-- 241

Query: 238 PGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWD 297
                +    +R RR G            A+ +R+ L IV+++  C+ PF+L QL A + 
Sbjct: 242 -----QRASFKRARRPG------------ARALRLVLGIVLLFWACFLPFWLWQLLAQYH 284

Query: 298 PEAPLEGAPFVLLMLLASL----NSCTNPWIYASFSSSVSSELRSLL---CCARGRTP-P 349
            +APL      ++  L +     NSC NP++Y   + +    LR  +       GR P P
Sbjct: 285 -QAPLAPRTARIVNYLTTCLTYGNSCANPFLYTLLTRNYRDHLRGRVRGPGSGGGRGPVP 343

Query: 350 SLGPQ 354
           SL P+
Sbjct: 344 SLQPR 348


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 80/328 (24%), Positives = 137/328 (41%), Gaps = 33/328 (10%)

Query: 46  IVFVAVALSNGLVLAALARRGRRGHWAPI-HVFIGHLCLADLAVALFQVLPQLAWKATDR 104
           IVFV   + N LV  A+    +  H   + + FI +L LAD+ V +  +   L    T+ 
Sbjct: 63  IVFVVALIGNVLVCVAV---WKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITET 119

Query: 105 FRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAW 164
           +    +LC+ + YLQ V +  S   +  + LDR  AIC P++       A     +++ W
Sbjct: 120 WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRA--RNSIVIIW 177

Query: 165 AFSLLLSLPQLFIFAQRNV-EGGSGVTDCWACFAEPWG----RRTYVTWIALMVFVAPTL 219
             S ++ +PQ  +     V  G +  T  +    E WG     + Y     L+ ++AP  
Sbjct: 178 IVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLC 237

Query: 220 GIAACQVLIFREIHASLVPGPSE---------RPGGRRRGRRTGSPGEGAHVSAAV---- 266
            +    + IFR++    +PG S          +P  + RG    +    + V+A +    
Sbjct: 238 LMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIR 297

Query: 267 --AKTVRMTLVIVVVYVLCWAPFFLVQL------WAAWDPEAPLEGAPFVLLMLLASLNS 318
              KT RM +++++V+ +C+ P  ++ +        A   +     A F     L   NS
Sbjct: 298 ARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANS 357

Query: 319 CTNPWIYASFSSSVSSELRSLL-CCARG 345
             NP IY   S     E ++   CC  G
Sbjct: 358 AANPIIYNFLSGKFREEFKAAFSCCCLG 385


>gi|4557857 somatostatin receptor 1 [Homo sapiens]
          Length = 391

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 79/306 (25%), Positives = 131/306 (42%), Gaps = 33/306 (10%)

Query: 43  LLSIVFVAVAL----SNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLA 98
           L+S ++  V L     N +V+  + R  +       +++I +L +AD  + L   +P L 
Sbjct: 60  LISFIYSVVCLVGLCGNSMVIYVILRYAKMK--TATNIYILNLAIADELLMLS--VPFLV 115

Query: 99  WKATDRFRGPDAL-CRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWN 157
                R     AL CR V  +  V M+ S Y +  +++DR+ A+  P+ A R+       
Sbjct: 116 TSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAK 175

Query: 158 RPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRT--YVTWIALMVFV 215
              L  W  SLL+ LP   +   R      G   C     EP  R    +V +  LM F+
Sbjct: 176 VVNLGVWVLSLLVILP--IVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFL 233

Query: 216 APTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLV 275
            P   I  C VLI  ++    +    ++   R+R  R               K   M ++
Sbjct: 234 LPVGAICLCYVLIIAKMRMVALKAGWQQ---RKRSER---------------KITLMVMM 275

Query: 276 IVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSE 335
           +V+V+V+CW PF++VQL   +  +   +     L ++L   NSC NP +Y   S +    
Sbjct: 276 VVMVFVICWMPFYVVQLVNVFAEQD--DATVSQLSVILGYANSCANPILYGFLSDNFKRS 333

Query: 336 LRSLLC 341
            + +LC
Sbjct: 334 FQRILC 339


>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
          Length = 370

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 96/339 (28%), Positives = 145/339 (42%), Gaps = 52/339 (15%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWK 100
           + LL  V V V L    +L  +  R RR H    +  IG+L L+D+ +    V   LA+ 
Sbjct: 63  IVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVT-NFLIGNLALSDVLMCTACVPLTLAYA 121

Query: 101 ATDR---FRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPM---LAYRHGSGA 154
              R   F G   LC  V +LQ V +Y S + +  + +DR+  +  P+   ++ R  + A
Sbjct: 122 FEPRGWVFGG--GLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYA 179

Query: 155 HWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWG-----RRTYVTWI 209
                VL  WA S +L+LP     A           D   C  E WG     R+ Y   +
Sbjct: 180 -----VLAIWALSAVLALPA----AVHTYHVELKPHDVRLC-EEFWGSQERQRQLYAWGL 229

Query: 210 ALMVFVAPTLGIAACQVLIFREIHASLVPG---PSERPGGRRRGRRTGSPGEGAHVSAAV 266
            L+ ++ P L I    V +  ++   +VPG    S+    R R RRT             
Sbjct: 230 LLVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFC----------- 278

Query: 267 AKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLML----LASLNSCTNP 322
                + +V+VVV+ +CW P  +  L    DP A ++   F L+ L    LA  ++C NP
Sbjct: 279 -----LLVVVVVVFAVCWLPLHVFNLLRDLDPHA-IDPYAFGLVQLLCHWLAMSSACYNP 332

Query: 323 WIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTA 361
           +IYA    S   ELR LL       P  + P  ++ T +
Sbjct: 333 FIYAWLHDSFREELRKLLVA----WPRKIAPHGQNMTVS 367


>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
          Length = 372

 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 97/357 (27%), Positives = 146/357 (40%), Gaps = 36/357 (10%)

Query: 2   LMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPL-LARAELALLSIVFVAVALSNGLVLA 60
           L A+ + A P   + PS  +N+S      +   L LA A  AL S V     L N LV+ 
Sbjct: 15  LFANASDAYPS--ACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMF 72

Query: 61  ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM 120
            + R  +      I++F  +L LAD A+A   +  Q A    + +   + LC+AV  +  
Sbjct: 73  GIVRYTKMKTATNIYIF--NLALAD-ALATSTLPFQSAKYLMETWPFGELLCKAVLSIDY 129

Query: 121 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ 180
             M+ S + +  M++DR+ A+C P+ A    + A      +  W  +  + +P + +   
Sbjct: 130 YNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVT 189

Query: 181 RNVEGGSGVTDCWACFAEP---WGRRTYVTWIALMVFVAPTLGIAACQ-VLIFREIHASL 236
           R  +   G   C   F  P   W   T +  + L  FV P L I  C  +++ R     L
Sbjct: 190 RPRD---GAVVCMLQFPSPSWYWDTVTKIC-VFLFAFVVPILIITVCYGLMLLRLRSVRL 245

Query: 237 VPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAP---FFLVQLW 293
           + G  E+    RR                     RM LV+V  +V+CWAP   F +V   
Sbjct: 246 LSGSKEKDRSLRR-------------------ITRMVLVVVGAFVVCWAPIHIFVIVWTL 286

Query: 294 AAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPS 350
              D   PL  A   L + L   NS  NP +YA    +     R L     GR  PS
Sbjct: 287 VDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPS 343


>gi|4503907 galanin receptor 3 [Homo sapiens]
          Length = 368

 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 84/328 (25%), Positives = 131/328 (39%), Gaps = 24/328 (7%)

Query: 24  SQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAP---IHVFIGH 80
           +Q   LD+   + A A   + +++F+   + NGLVLA L + G      P     +FI +
Sbjct: 4   AQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILN 63

Query: 81  LCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRA 140
           L +ADL   L  V  Q      D +     +C+AV  L  + MYASS+ + A+++DR+ A
Sbjct: 64  LAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLA 123

Query: 141 ICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPW 200
           +  P+ +    +  +    V + W  + L S P L  +              W    E  
Sbjct: 124 VRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAW----EDA 179

Query: 201 GRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGA 260
            RR          ++ P   ++       R + A++  GP+       R R TG  G   
Sbjct: 180 RRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAV--GPAGAAAAEARRRATGRAG--- 234

Query: 261 HVSAAVAKTVRMTLVIVVVYVLCWAPF--FLVQLWAAWDPEAPLEGAPFVLLMLLASLNS 318
                     R  L +  +Y LCW P    ++  W      +P   A  +    LA  NS
Sbjct: 235 ----------RAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANS 284

Query: 319 CTNPWIYASFSSSVSSELRSLLCCARGR 346
           C NP +YA  S    +  R L  C R R
Sbjct: 285 CLNPLVYALASRHFRARFRRLWPCGRRR 312


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 87/340 (25%), Positives = 138/340 (40%), Gaps = 47/340 (13%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWK 100
           + L   V V   L N LV+  + R  +      I++F  +L LAD  V L      L ++
Sbjct: 55  VGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIF--NLALADTLVLL-----TLPFQ 107

Query: 101 ATDRFRG----PDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHW 156
            TD   G     +ALC+ V  +    M+ S++ + AM++DR+ AIC P+ A    + +  
Sbjct: 108 GTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKA 167

Query: 157 NRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEP---WGRRTYVTWIALMV 213
               +  WA + ++ +P + I     VE      +C      P   WG   +   I L  
Sbjct: 168 QAVNVAIWALASVVGVP-VAIMGSAQVEDEE--IECLVEIPTPQDYWG-PVFAICIFLFS 223

Query: 214 FVAPTLGIAACQVLIFREIH-ASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRM 272
           F+ P L I+ C  L+ R +    L+ G  E+    RR                     R+
Sbjct: 224 FIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRR-------------------ITRL 264

Query: 273 TLVIVVVYVLCWAP--FFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSS 330
            LV+V V+V CW P   F++       P +    A       L  +NSC NP +YA    
Sbjct: 265 VLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDE 324

Query: 331 SVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTS 370
           +  +  R   C +  R       +D   +    S+AKD +
Sbjct: 325 NFKACFRKFCCASALR-------RDVQVSDRVRSIAKDVA 357


>gi|33286424 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 87/340 (25%), Positives = 138/340 (40%), Gaps = 47/340 (13%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWK 100
           + L   V V   L N LV+  + R  +      I++F  +L LAD  V L      L ++
Sbjct: 55  VGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIF--NLALADTLVLL-----TLPFQ 107

Query: 101 ATDRFRG----PDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHW 156
            TD   G     +ALC+ V  +    M+ S++ + AM++DR+ AIC P+ A    + +  
Sbjct: 108 GTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKA 167

Query: 157 NRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEP---WGRRTYVTWIALMV 213
               +  WA + ++ +P + I     VE      +C      P   WG   +   I L  
Sbjct: 168 QAVNVAIWALASVVGVP-VAIMGSAQVEDEE--IECLVEIPTPQDYWG-PVFAICIFLFS 223

Query: 214 FVAPTLGIAACQVLIFREIH-ASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRM 272
           F+ P L I+ C  L+ R +    L+ G  E+    RR                     R+
Sbjct: 224 FIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRR-------------------ITRL 264

Query: 273 TLVIVVVYVLCWAP--FFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSS 330
            LV+V V+V CW P   F++       P +    A       L  +NSC NP +YA    
Sbjct: 265 VLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDE 324

Query: 331 SVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTS 370
           +  +  R   C +  R       +D   +    S+AKD +
Sbjct: 325 NFKACFRKFCCASALR-------RDVQVSDRVRSIAKDVA 357


>gi|222080095 orexin receptor 1 [Homo sapiens]
          Length = 425

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 90/345 (26%), Positives = 143/345 (41%), Gaps = 44/345 (12%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPI-HVFIGHLCLADLAVALFQVLPQLAW 99
           +A    VFV   + N LV  A+    R  H   + + FI +L LAD+ V    +   L  
Sbjct: 50  IAAYVAVFVVALVGNTLVCLAV---WRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLV 106

Query: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
             T+ +    ALC+ + YLQ V +  +   +  + LDR  AIC P+L       A  +  
Sbjct: 107 DITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGS-- 164

Query: 160 VLVAWAFSLLLSLPQLFIFAQRNV-EGGSGVTDCWACFAEPWG----RRTYVTWIALMVF 214
           +L  WA SL + +PQ  +    +V    +  T  ++   E W      + Y +   ++ +
Sbjct: 165 ILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTY 224

Query: 215 VAPTLGIAACQVLIFREIHASLVPG-----------PSERPGGRRRGRRTGSPGEGAHVS 263
           +AP   +A     IFR++    +PG           PS++ G   +G  +G P   A   
Sbjct: 225 LAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQG-LSGEPQPRARAF 283

Query: 264 AAVA-------KTVRMTLVIVVVYVLCWAPFFLVQLW--------AAWDPEAPLEGAPFV 308
            A         KT +M +V+++V+ LC+ P  ++ +          A D EA    A F 
Sbjct: 284 LAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVY--ACFT 341

Query: 309 LLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGP 353
               L   NS  NP IY   S     + ++   C      P LGP
Sbjct: 342 FSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCCL----PGLGP 382


>gi|4885057 apelin receptor [Homo sapiens]
          Length = 380

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 86/324 (26%), Positives = 134/324 (41%), Gaps = 45/324 (13%)

Query: 42  ALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKA 101
           A+  +VF+     NGLVL  + R  R    +   +FI  L +ADL   +   LP   W A
Sbjct: 33  AIYMLVFLLGTTGNGLVLWTVFRSSREKRRSA-DIFIASLAVADLTFVV--TLP--LW-A 86

Query: 102 TDRFRGPD-----ALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHW 156
           T  +R  D       C+   YL  V MYAS + +  ++ DR+ AI RP+   R       
Sbjct: 87  TYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSG 146

Query: 157 NRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCW------ACFAEPWGRRTYVTWIA 210
                V W  + LL++P + +    ++E  + V  C+      A  +  W     +   +
Sbjct: 147 AVATAVLWVLAALLAMPVMVLRTTGDLENTTKV-QCYMDYSMVATVSSEWAWEVGLGVSS 205

Query: 211 LMV-FVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKT 269
             V FV P   +  C   I + I         ER  G R+ RR  S              
Sbjct: 206 TTVGFVVPFTIMLTCYFFIAQTIAGHF---RKERIEGLRKRRRLLS-------------- 248

Query: 270 VRMTLVIVVVYVLCWAPFFLVQLWAAWDP--EAPLEGAPFVLLML-----LASLNSCTNP 322
             + +V+VV + LCW P+ LV+           P +   F++ +      ++ +NSC NP
Sbjct: 249 --IIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYVNSCLNP 306

Query: 323 WIYASFSSSVSSELRSLLCCARGR 346
           ++YA F         S+LCC + R
Sbjct: 307 FLYAFFDPRFRQACTSMLCCGQSR 330


>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
          Length = 493

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 77/325 (23%), Positives = 129/325 (39%), Gaps = 38/325 (11%)

Query: 11  PGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGH 70
           P  P+   L    S   P  +   + A   +AL SIV V     N LV+  + R  +   
Sbjct: 137 PCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKT 196

Query: 71  WAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGP----DALCRAVKYLQMVGMYAS 126
              I++F  +L LAD           L +++ +   G       LC+ V  +    M+ S
Sbjct: 197 ATNIYIF--NLALADALAT-----STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTS 249

Query: 127 SYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGG 186
            + +  M++DR+ A+C P+ A    +  +     +  W  S  + LP +F+   +  +G 
Sbjct: 250 IFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS 309

Query: 187 SGVTDCWACFAEP--WGRRTYVTWIALMVFVAPTLGIAACQ-VLIFREIHASLVPGPSER 243
               DC   F+ P  +        + +  F+ P L I  C  ++I R     ++ G  E+
Sbjct: 310 ---IDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEK 366

Query: 244 PGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAA--WDPEAP 301
               RR                     RM LV+V V+++CW P  +  +  A    PE  
Sbjct: 367 DRNLRR-------------------ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETT 407

Query: 302 LEGAPFVLLMLLASLNSCTNPWIYA 326
            +   +   + L   NSC NP +YA
Sbjct: 408 FQTVSWHFCIALGYTNSCLNPVLYA 432


>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
          Length = 400

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 77/325 (23%), Positives = 129/325 (39%), Gaps = 38/325 (11%)

Query: 11  PGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGH 70
           P  P+   L    S   P  +   + A   +AL SIV V     N LV+  + R  +   
Sbjct: 44  PCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKT 103

Query: 71  WAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGP----DALCRAVKYLQMVGMYAS 126
              I++F  +L LAD           L +++ +   G       LC+ V  +    M+ S
Sbjct: 104 ATNIYIF--NLALADALAT-----STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTS 156

Query: 127 SYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGG 186
            + +  M++DR+ A+C P+ A    +  +     +  W  S  + LP +F+   +  +G 
Sbjct: 157 IFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS 216

Query: 187 SGVTDCWACFAEP--WGRRTYVTWIALMVFVAPTLGIAACQ-VLIFREIHASLVPGPSER 243
               DC   F+ P  +        + +  F+ P L I  C  ++I R     ++ G  E+
Sbjct: 217 ---IDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEK 273

Query: 244 PGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAA--WDPEAP 301
               RR                     RM LV+V V+++CW P  +  +  A    PE  
Sbjct: 274 DRNLRR-------------------ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETT 314

Query: 302 LEGAPFVLLMLLASLNSCTNPWIYA 326
            +   +   + L   NSC NP +YA
Sbjct: 315 FQTVSWHFCIALGYTNSCLNPVLYA 339


>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
          Length = 420

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 77/325 (23%), Positives = 129/325 (39%), Gaps = 38/325 (11%)

Query: 11  PGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGH 70
           P  P+   L    S   P  +   + A   +AL SIV V     N LV+  + R  +   
Sbjct: 44  PCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKT 103

Query: 71  WAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGP----DALCRAVKYLQMVGMYAS 126
              I++F  +L LAD           L +++ +   G       LC+ V  +    M+ S
Sbjct: 104 ATNIYIF--NLALADALAT-----STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTS 156

Query: 127 SYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGG 186
            + +  M++DR+ A+C P+ A    +  +     +  W  S  + LP +F+   +  +G 
Sbjct: 157 IFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS 216

Query: 187 SGVTDCWACFAEP--WGRRTYVTWIALMVFVAPTLGIAACQ-VLIFREIHASLVPGPSER 243
               DC   F+ P  +        + +  F+ P L I  C  ++I R     ++ G  E+
Sbjct: 217 ---IDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEK 273

Query: 244 PGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAA--WDPEAP 301
               RR                     RM LV+V V+++CW P  +  +  A    PE  
Sbjct: 274 DRNLRR-------------------ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETT 314

Query: 302 LEGAPFVLLMLLASLNSCTNPWIYA 326
            +   +   + L   NSC NP +YA
Sbjct: 315 FQTVSWHFCIALGYTNSCLNPVLYA 339


>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
          Length = 397

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 77/325 (23%), Positives = 129/325 (39%), Gaps = 38/325 (11%)

Query: 11  PGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGH 70
           P  P+   L    S   P  +   + A   +AL SIV V     N LV+  + R  +   
Sbjct: 44  PCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKT 103

Query: 71  WAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGP----DALCRAVKYLQMVGMYAS 126
              I++F  +L LAD           L +++ +   G       LC+ V  +    M+ S
Sbjct: 104 ATNIYIF--NLALADALAT-----STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTS 156

Query: 127 SYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGG 186
            + +  M++DR+ A+C P+ A    +  +     +  W  S  + LP +F+   +  +G 
Sbjct: 157 IFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS 216

Query: 187 SGVTDCWACFAEP--WGRRTYVTWIALMVFVAPTLGIAACQ-VLIFREIHASLVPGPSER 243
               DC   F+ P  +        + +  F+ P L I  C  ++I R     ++ G  E+
Sbjct: 217 ---IDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEK 273

Query: 244 PGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAA--WDPEAP 301
               RR                     RM LV+V V+++CW P  +  +  A    PE  
Sbjct: 274 DRNLRR-------------------ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETT 314

Query: 302 LEGAPFVLLMLLASLNSCTNPWIYA 326
            +   +   + L   NSC NP +YA
Sbjct: 315 FQTVSWHFCIALGYTNSCLNPVLYA 339


>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
          Length = 403

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 77/325 (23%), Positives = 129/325 (39%), Gaps = 38/325 (11%)

Query: 11  PGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGH 70
           P  P+   L    S   P  +   + A   +AL SIV V     N LV+  + R  +   
Sbjct: 44  PCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKT 103

Query: 71  WAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGP----DALCRAVKYLQMVGMYAS 126
              I++F  +L LAD           L +++ +   G       LC+ V  +    M+ S
Sbjct: 104 ATNIYIF--NLALADALAT-----STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTS 156

Query: 127 SYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGG 186
            + +  M++DR+ A+C P+ A    +  +     +  W  S  + LP +F+   +  +G 
Sbjct: 157 IFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS 216

Query: 187 SGVTDCWACFAEP--WGRRTYVTWIALMVFVAPTLGIAACQ-VLIFREIHASLVPGPSER 243
               DC   F+ P  +        + +  F+ P L I  C  ++I R     ++ G  E+
Sbjct: 217 ---IDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEK 273

Query: 244 PGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAA--WDPEAP 301
               RR                     RM LV+V V+++CW P  +  +  A    PE  
Sbjct: 274 DRNLRR-------------------ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETT 314

Query: 302 LEGAPFVLLMLLASLNSCTNPWIYA 326
            +   +   + L   NSC NP +YA
Sbjct: 315 FQTVSWHFCIALGYTNSCLNPVLYA 339


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.135    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,919,663
Number of Sequences: 37866
Number of extensions: 649988
Number of successful extensions: 4431
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 208
Number of HSP's successfully gapped in prelim test: 346
Number of HSP's that attempted gapping in prelim test: 3691
Number of HSP's gapped (non-prelim): 680
length of query: 371
length of database: 18,247,518
effective HSP length: 104
effective length of query: 267
effective length of database: 14,309,454
effective search space: 3820624218
effective search space used: 3820624218
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.