Search of human proteins with 4557311

Search of human proteins with 4557311

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557311 adenosine monophosphate deaminase 1 (isoform M)
[Homo sapiens]
         (747 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557311 adenosine monophosphate deaminase 1 (isoform M) [Homo...  1532   0.0  
gi|4502079 adenosine monophosphate deaminase 3 isoform 1A [Homo ...   929   0.0  
gi|70906428 adenosine monophosphate deaminase 3 isoform 1C [Homo...   929   0.0  
gi|70906426 adenosine monophosphate deaminase 3 isoform 1B [Homo...   929   0.0  
gi|55925574 adenosine monophosphate deaminase 2 (isoform L) isof...   728   0.0  
gi|34147621 adenosine monophosphate deaminase 2 (isoform L) isof...   728   0.0  
gi|21264318 adenosine monophosphate deaminase 2 (isoform L) isof...   728   0.0  
gi|29029552 cat eye syndrome critical region protein 1 isoform b...    38   0.039
gi|29029550 cat eye syndrome critical region protein 1 isoform a...    38   0.039
gi|71061468 centromere protein E [Homo sapiens]                        33   1.3  
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]          31   3.7  
gi|24429574 solute carrier family 38, member 6 [Homo sapiens]          30   6.3  
gi|4504505 hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]     30   8.2  

>gi|4557311 adenosine monophosphate deaminase 1 (isoform M) [Homo
           sapiens]
          Length = 747

 Score = 1532 bits (3967), Expect = 0.0
 Identities = 747/747 (100%), Positives = 747/747 (100%)

Query: 1   MPLFKLPAEEKQIDDAMRNFAEKVFASEVKDEGGRQEISPFDVDEICPISHHEMQAHIFH 60
           MPLFKLPAEEKQIDDAMRNFAEKVFASEVKDEGGRQEISPFDVDEICPISHHEMQAHIFH
Sbjct: 1   MPLFKLPAEEKQIDDAMRNFAEKVFASEVKDEGGRQEISPFDVDEICPISHHEMQAHIFH 60

Query: 61  LETLSTSTEARRKKRFQGRKTVNLSIPLSETSSTKLSHIDEYISSSPTYQTVPDFQRVQI 120
           LETLSTSTEARRKKRFQGRKTVNLSIPLSETSSTKLSHIDEYISSSPTYQTVPDFQRVQI
Sbjct: 61  LETLSTSTEARRKKRFQGRKTVNLSIPLSETSSTKLSHIDEYISSSPTYQTVPDFQRVQI 120

Query: 121 TGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVANESF 180
           TGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVANESF
Sbjct: 121 TGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVANESF 180

Query: 181 YPVFTPPVKKGEDPFRTDNLPENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPNLDTF 240
           YPVFTPPVKKGEDPFRTDNLPENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPNLDTF
Sbjct: 181 YPVFTPPVKKGEDPFRTDNLPENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPNLDTF 240

Query: 241 LDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKV 300
           LDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKV
Sbjct: 241 LDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKV 300

Query: 301 DTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTLKELFAKLKMHPYDLTVDSL 360
           DTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTLKELFAKLKMHPYDLTVDSL
Sbjct: 301 DTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTLKELFAKLKMHPYDLTVDSL 360

Query: 361 DVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVEAKYQ 420
           DVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVEAKYQ
Sbjct: 361 DVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVEAKYQ 420

Query: 421 HAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLE 480
           HAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLE
Sbjct: 421 HAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLE 480

Query: 481 NIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGHMFSSKSPKPQEWTLEKNPS 540
           NIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGHMFSSKSPKPQEWTLEKNPS
Sbjct: 481 NIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGHMFSSKSPKPQEWTLEKNPS 540

Query: 541 YTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADDISHGLNLKK 600
           YTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADDISHGLNLKK
Sbjct: 541 YTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADDISHGLNLKK 600

Query: 601 SPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEP 660
           SPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEP
Sbjct: 601 SPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEP 660

Query: 661 LMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFLGDNYLEEGPAGNDIRRTNV 720
           LMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFLGDNYLEEGPAGNDIRRTNV
Sbjct: 661 LMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFLGDNYLEEGPAGNDIRRTNV 720

Query: 721 AQIRMAYRYETWCYELNLIAEGLKSTE 747
           AQIRMAYRYETWCYELNLIAEGLKSTE
Sbjct: 721 AQIRMAYRYETWCYELNLIAEGLKSTE 747


>gi|4502079 adenosine monophosphate deaminase 3 isoform 1A [Homo
           sapiens]
          Length = 776

 Score =  929 bits (2402), Expect = 0.0
 Identities = 452/751 (60%), Positives = 571/751 (76%), Gaps = 16/751 (2%)

Query: 12  QIDDAMRNFAEKVFASEVKDEGGRQEISPFDVDEICPISHHEMQAHIFHLETLSTST--E 69
           ++D+ +R  AEKVFA  +++E  +  +S F V E CPI   E +      E     +   
Sbjct: 21  EVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVET 80

Query: 70  ARRKKRFQGRKTVNLSIPLSE--------TSSTKLSHIDEYISSSPTYQT-----VPDFQ 116
           A+RKK F+  ++ +LS+ +           +S  +S     ++ + +  T     +P+FQ
Sbjct: 81  AKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQ 140

Query: 117 RVQITGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVA 176
           RV I+GDY +G+T+ED+E   K L +AL IREKY + ++ RFP+  S+YL +   +    
Sbjct: 141 RVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYLGHPRADTAPP 200

Query: 177 NESFYPVFTPPVKKGEDPFRTDNLPENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPN 236
            E   P F PP    EDP+  D+ P NL Y + M+ G+++VY N+  +   EP  LPYP+
Sbjct: 201 EEGL-PDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYPD 259

Query: 237 LDTFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYN 296
           L+T+  DM+ +LALI  GP KTY HRRL FL SKF +H+MLNEM E KELK+NPHRDFYN
Sbjct: 260 LETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYN 319

Query: 297 CRKVDTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTLKELFAKLKMHPYDLT 356
            RKVDTHIHAAACMNQKHLLRFIK +YQ + DR V   + + +TL+++F  L M PYDLT
Sbjct: 320 VRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLT 379

Query: 357 VDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVE 416
           VDSLDVHAGRQTF RFDKFN KYNPVGASELRDLYLKT+NY+ GEYFA ++KEV  +L E
Sbjct: 380 VDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEE 439

Query: 417 AKYQHAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPRIYDVFRSKNFLPHFG 476
           +KYQ++EPRLSIYGRSP+EW  L+ WF+ ++++ PNM W+IQVPRIYD+FRSK  LP+FG
Sbjct: 440 SKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFG 499

Query: 477 KMLENIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGHMFSSKSPKPQEWTLE 536
           KMLENIF+P+F+ATINPQ   EL +FLK++TGFDSVDDESKHS HMFS KSP P  WT E
Sbjct: 500 KMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTSE 559

Query: 537 KNPSYTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADDISHGL 596
           +NP Y+YY YYMYANIMVLN+LR+ERG++TFLFRPHCGEAG++THL++AF+ AD+ISHGL
Sbjct: 560 QNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGL 619

Query: 597 NLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHF 656
            LKKSPVLQYL++LAQIPIAMSPLSNNSLFLEY+KNP  +FL KGL +SLSTDDPMQFH+
Sbjct: 620 LLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHY 679

Query: 657 TKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFLGDNYLEEGPAGNDIR 716
           TKE LMEEYAIAAQV+KLSTCD+CE+ARNSVLQ G+SH+EK KFLG NY +EGP GNDIR
Sbjct: 680 TKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIR 739

Query: 717 RTNVAQIRMAYRYETWCYELNLIAEGLKSTE 747
           +TNVAQIRMA+RYET C EL+ +++ +KS E
Sbjct: 740 KTNVAQIRMAFRYETLCNELSFLSDAMKSEE 770


>gi|70906428 adenosine monophosphate deaminase 3 isoform 1C [Homo
           sapiens]
          Length = 774

 Score =  929 bits (2402), Expect = 0.0
 Identities = 452/751 (60%), Positives = 571/751 (76%), Gaps = 16/751 (2%)

Query: 12  QIDDAMRNFAEKVFASEVKDEGGRQEISPFDVDEICPISHHEMQAHIFHLETLSTST--E 69
           ++D+ +R  AEKVFA  +++E  +  +S F V E CPI   E +      E     +   
Sbjct: 19  EVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVET 78

Query: 70  ARRKKRFQGRKTVNLSIPLSE--------TSSTKLSHIDEYISSSPTYQT-----VPDFQ 116
           A+RKK F+  ++ +LS+ +           +S  +S     ++ + +  T     +P+FQ
Sbjct: 79  AKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQ 138

Query: 117 RVQITGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVA 176
           RV I+GDY +G+T+ED+E   K L +AL IREKY + ++ RFP+  S+YL +   +    
Sbjct: 139 RVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYLGHPRADTAPP 198

Query: 177 NESFYPVFTPPVKKGEDPFRTDNLPENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPN 236
            E   P F PP    EDP+  D+ P NL Y + M+ G+++VY N+  +   EP  LPYP+
Sbjct: 199 EEGL-PDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYPD 257

Query: 237 LDTFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYN 296
           L+T+  DM+ +LALI  GP KTY HRRL FL SKF +H+MLNEM E KELK+NPHRDFYN
Sbjct: 258 LETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYN 317

Query: 297 CRKVDTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTLKELFAKLKMHPYDLT 356
            RKVDTHIHAAACMNQKHLLRFIK +YQ + DR V   + + +TL+++F  L M PYDLT
Sbjct: 318 VRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLT 377

Query: 357 VDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVE 416
           VDSLDVHAGRQTF RFDKFN KYNPVGASELRDLYLKT+NY+ GEYFA ++KEV  +L E
Sbjct: 378 VDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEE 437

Query: 417 AKYQHAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPRIYDVFRSKNFLPHFG 476
           +KYQ++EPRLSIYGRSP+EW  L+ WF+ ++++ PNM W+IQVPRIYD+FRSK  LP+FG
Sbjct: 438 SKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFG 497

Query: 477 KMLENIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGHMFSSKSPKPQEWTLE 536
           KMLENIF+P+F+ATINPQ   EL +FLK++TGFDSVDDESKHS HMFS KSP P  WT E
Sbjct: 498 KMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTSE 557

Query: 537 KNPSYTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADDISHGL 596
           +NP Y+YY YYMYANIMVLN+LR+ERG++TFLFRPHCGEAG++THL++AF+ AD+ISHGL
Sbjct: 558 QNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGL 617

Query: 597 NLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHF 656
            LKKSPVLQYL++LAQIPIAMSPLSNNSLFLEY+KNP  +FL KGL +SLSTDDPMQFH+
Sbjct: 618 LLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHY 677

Query: 657 TKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFLGDNYLEEGPAGNDIR 716
           TKE LMEEYAIAAQV+KLSTCD+CE+ARNSVLQ G+SH+EK KFLG NY +EGP GNDIR
Sbjct: 678 TKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIR 737

Query: 717 RTNVAQIRMAYRYETWCYELNLIAEGLKSTE 747
           +TNVAQIRMA+RYET C EL+ +++ +KS E
Sbjct: 738 KTNVAQIRMAFRYETLCNELSFLSDAMKSEE 768


>gi|70906426 adenosine monophosphate deaminase 3 isoform 1B [Homo
           sapiens]
          Length = 767

 Score =  929 bits (2402), Expect = 0.0
 Identities = 452/751 (60%), Positives = 571/751 (76%), Gaps = 16/751 (2%)

Query: 12  QIDDAMRNFAEKVFASEVKDEGGRQEISPFDVDEICPISHHEMQAHIFHLETLSTST--E 69
           ++D+ +R  AEKVFA  +++E  +  +S F V E CPI   E +      E     +   
Sbjct: 12  EVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVET 71

Query: 70  ARRKKRFQGRKTVNLSIPLSE--------TSSTKLSHIDEYISSSPTYQT-----VPDFQ 116
           A+RKK F+  ++ +LS+ +           +S  +S     ++ + +  T     +P+FQ
Sbjct: 72  AKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQ 131

Query: 117 RVQITGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVA 176
           RV I+GDY +G+T+ED+E   K L +AL IREKY + ++ RFP+  S+YL +   +    
Sbjct: 132 RVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYLGHPRADTAPP 191

Query: 177 NESFYPVFTPPVKKGEDPFRTDNLPENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPN 236
            E   P F PP    EDP+  D+ P NL Y + M+ G+++VY N+  +   EP  LPYP+
Sbjct: 192 EEGL-PDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYPD 250

Query: 237 LDTFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYN 296
           L+T+  DM+ +LALI  GP KTY HRRL FL SKF +H+MLNEM E KELK+NPHRDFYN
Sbjct: 251 LETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYN 310

Query: 297 CRKVDTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTLKELFAKLKMHPYDLT 356
            RKVDTHIHAAACMNQKHLLRFIK +YQ + DR V   + + +TL+++F  L M PYDLT
Sbjct: 311 VRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLT 370

Query: 357 VDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVE 416
           VDSLDVHAGRQTF RFDKFN KYNPVGASELRDLYLKT+NY+ GEYFA ++KEV  +L E
Sbjct: 371 VDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEE 430

Query: 417 AKYQHAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPRIYDVFRSKNFLPHFG 476
           +KYQ++EPRLSIYGRSP+EW  L+ WF+ ++++ PNM W+IQVPRIYD+FRSK  LP+FG
Sbjct: 431 SKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFG 490

Query: 477 KMLENIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGHMFSSKSPKPQEWTLE 536
           KMLENIF+P+F+ATINPQ   EL +FLK++TGFDSVDDESKHS HMFS KSP P  WT E
Sbjct: 491 KMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTSE 550

Query: 537 KNPSYTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADDISHGL 596
           +NP Y+YY YYMYANIMVLN+LR+ERG++TFLFRPHCGEAG++THL++AF+ AD+ISHGL
Sbjct: 551 QNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGL 610

Query: 597 NLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHF 656
            LKKSPVLQYL++LAQIPIAMSPLSNNSLFLEY+KNP  +FL KGL +SLSTDDPMQFH+
Sbjct: 611 LLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHY 670

Query: 657 TKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFLGDNYLEEGPAGNDIR 716
           TKE LMEEYAIAAQV+KLSTCD+CE+ARNSVLQ G+SH+EK KFLG NY +EGP GNDIR
Sbjct: 671 TKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIR 730

Query: 717 RTNVAQIRMAYRYETWCYELNLIAEGLKSTE 747
           +TNVAQIRMA+RYET C EL+ +++ +KS E
Sbjct: 731 KTNVAQIRMAFRYETLCNELSFLSDAMKSEE 761


>gi|55925574 adenosine monophosphate deaminase 2 (isoform L) isoform
           3 [Homo sapiens]
          Length = 760

 Score =  728 bits (1878), Expect = 0.0
 Identities = 356/644 (55%), Positives = 471/644 (73%), Gaps = 13/644 (2%)

Query: 114 DFQRVQITGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEA 173
           +FQRV I+G+   GV   D     K + RAL IREKYM  S Q F  T  +YL+ +  E 
Sbjct: 99  EFQRVTISGEEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQL-AEK 157

Query: 174 WVANESFY-----------PVFTPPVKKGE-DPFRTDNLPENLGYHLKMKDGVVYVYPNE 221
            +   ++            PV  P +++   +      +P +LG  L+M  GVV+VY   
Sbjct: 158 PLETRTYEQGPDTPVSADAPVHPPALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRR 217

Query: 222 AAVSKDEPKPLPYPNLDTFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMD 281
                     LPYP+L  F+ D+N L+ALI  GP+K++ +RRL++LSSKFQ+H +LNEM 
Sbjct: 218 EPDEHCSEVELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMK 277

Query: 282 ELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTL 341
           EL   K  PHRDFYN RKVDTHIHA++CMNQKHLLRFIK++ +   + +V+  + +  TL
Sbjct: 278 ELAAQKKVPHRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTL 337

Query: 342 KELFAKLKMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGE 401
           +E+F  + +  YDL+VD+LDVHA R TF RFDKFN KYNP+G S LR++++KTDN ++G+
Sbjct: 338 REVFESMNLTAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGK 397

Query: 402 YFATIIKEVGADLVEAKYQHAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPR 461
           YFA IIKEV +DL E+KYQ+AE RLSIYGRS DEW KL+ W V +R+H PN+ W++QVPR
Sbjct: 398 YFAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPR 457

Query: 462 IYDVFRSKNFLPHFGKMLENIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGH 521
           ++DV+R+K  L +F +MLENIF+P+FEAT++P + PEL +FL+H+ GFDSVDDESK   H
Sbjct: 458 LFDVYRTKGQLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENH 517

Query: 522 MFSSKSPKPQEWTLEKNPSYTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTH 581
           +F+ +SP P+ W  E NP Y YY YY +AN+ +LN LR++RG +TF+ RPHCGEAG + H
Sbjct: 518 VFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHH 577

Query: 582 LMTAFMIADDISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKG 641
           L++AFM+A++ISHGL L+K+PVLQYL++LAQI IAMSPLSNNSLFL Y +NP  ++L +G
Sbjct: 578 LVSAFMLAENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRG 637

Query: 642 LMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFL 701
           LM+SLSTDDP+QFHFTKEPLMEEY+IA QV+KLS+CDMCE+ARNSVL  G SH+ K  +L
Sbjct: 638 LMVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWL 697

Query: 702 GDNYLEEGPAGNDIRRTNVAQIRMAYRYETWCYELNLIAEGLKS 745
           G NY +EGP GNDIRRTNV  IR+ YRYET C EL LI + ++S
Sbjct: 698 GPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQS 741


>gi|34147621 adenosine monophosphate deaminase 2 (isoform L) isoform
           2 [Homo sapiens]
          Length = 798

 Score =  728 bits (1878), Expect = 0.0
 Identities = 356/644 (55%), Positives = 471/644 (73%), Gaps = 13/644 (2%)

Query: 114 DFQRVQITGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEA 173
           +FQRV I+G+   GV   D     K + RAL IREKYM  S Q F  T  +YL+ +  E 
Sbjct: 137 EFQRVTISGEEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQL-AEK 195

Query: 174 WVANESFY-----------PVFTPPVKKGE-DPFRTDNLPENLGYHLKMKDGVVYVYPNE 221
            +   ++            PV  P +++   +      +P +LG  L+M  GVV+VY   
Sbjct: 196 PLETRTYEQGPDTPVSADAPVHPPALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRR 255

Query: 222 AAVSKDEPKPLPYPNLDTFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMD 281
                     LPYP+L  F+ D+N L+ALI  GP+K++ +RRL++LSSKFQ+H +LNEM 
Sbjct: 256 EPDEHCSEVELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMK 315

Query: 282 ELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTL 341
           EL   K  PHRDFYN RKVDTHIHA++CMNQKHLLRFIK++ +   + +V+  + +  TL
Sbjct: 316 ELAAQKKVPHRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTL 375

Query: 342 KELFAKLKMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGE 401
           +E+F  + +  YDL+VD+LDVHA R TF RFDKFN KYNP+G S LR++++KTDN ++G+
Sbjct: 376 REVFESMNLTAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGK 435

Query: 402 YFATIIKEVGADLVEAKYQHAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPR 461
           YFA IIKEV +DL E+KYQ+AE RLSIYGRS DEW KL+ W V +R+H PN+ W++QVPR
Sbjct: 436 YFAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPR 495

Query: 462 IYDVFRSKNFLPHFGKMLENIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGH 521
           ++DV+R+K  L +F +MLENIF+P+FEAT++P + PEL +FL+H+ GFDSVDDESK   H
Sbjct: 496 LFDVYRTKGQLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENH 555

Query: 522 MFSSKSPKPQEWTLEKNPSYTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTH 581
           +F+ +SP P+ W  E NP Y YY YY +AN+ +LN LR++RG +TF+ RPHCGEAG + H
Sbjct: 556 VFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHH 615

Query: 582 LMTAFMIADDISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKG 641
           L++AFM+A++ISHGL L+K+PVLQYL++LAQI IAMSPLSNNSLFL Y +NP  ++L +G
Sbjct: 616 LVSAFMLAENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRG 675

Query: 642 LMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFL 701
           LM+SLSTDDP+QFHFTKEPLMEEY+IA QV+KLS+CDMCE+ARNSVL  G SH+ K  +L
Sbjct: 676 LMVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWL 735

Query: 702 GDNYLEEGPAGNDIRRTNVAQIRMAYRYETWCYELNLIAEGLKS 745
           G NY +EGP GNDIRRTNV  IR+ YRYET C EL LI + ++S
Sbjct: 736 GPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQS 779


>gi|21264318 adenosine monophosphate deaminase 2 (isoform L) isoform
           1 [Homo sapiens]
          Length = 879

 Score =  728 bits (1878), Expect = 0.0
 Identities = 356/644 (55%), Positives = 471/644 (73%), Gaps = 13/644 (2%)

Query: 114 DFQRVQITGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEA 173
           +FQRV I+G+   GV   D     K + RAL IREKYM  S Q F  T  +YL+ +  E 
Sbjct: 218 EFQRVTISGEEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQL-AEK 276

Query: 174 WVANESFY-----------PVFTPPVKKGE-DPFRTDNLPENLGYHLKMKDGVVYVYPNE 221
            +   ++            PV  P +++   +      +P +LG  L+M  GVV+VY   
Sbjct: 277 PLETRTYEQGPDTPVSADAPVHPPALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRR 336

Query: 222 AAVSKDEPKPLPYPNLDTFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMD 281
                     LPYP+L  F+ D+N L+ALI  GP+K++ +RRL++LSSKFQ+H +LNEM 
Sbjct: 337 EPDEHCSEVELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMK 396

Query: 282 ELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTL 341
           EL   K  PHRDFYN RKVDTHIHA++CMNQKHLLRFIK++ +   + +V+  + +  TL
Sbjct: 397 ELAAQKKVPHRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTL 456

Query: 342 KELFAKLKMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGE 401
           +E+F  + +  YDL+VD+LDVHA R TF RFDKFN KYNP+G S LR++++KTDN ++G+
Sbjct: 457 REVFESMNLTAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGK 516

Query: 402 YFATIIKEVGADLVEAKYQHAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPR 461
           YFA IIKEV +DL E+KYQ+AE RLSIYGRS DEW KL+ W V +R+H PN+ W++QVPR
Sbjct: 517 YFAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPR 576

Query: 462 IYDVFRSKNFLPHFGKMLENIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGH 521
           ++DV+R+K  L +F +MLENIF+P+FEAT++P + PEL +FL+H+ GFDSVDDESK   H
Sbjct: 577 LFDVYRTKGQLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENH 636

Query: 522 MFSSKSPKPQEWTLEKNPSYTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTH 581
           +F+ +SP P+ W  E NP Y YY YY +AN+ +LN LR++RG +TF+ RPHCGEAG + H
Sbjct: 637 VFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHH 696

Query: 582 LMTAFMIADDISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKG 641
           L++AFM+A++ISHGL L+K+PVLQYL++LAQI IAMSPLSNNSLFL Y +NP  ++L +G
Sbjct: 697 LVSAFMLAENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRG 756

Query: 642 LMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFL 701
           LM+SLSTDDP+QFHFTKEPLMEEY+IA QV+KLS+CDMCE+ARNSVL  G SH+ K  +L
Sbjct: 757 LMVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWL 816

Query: 702 GDNYLEEGPAGNDIRRTNVAQIRMAYRYETWCYELNLIAEGLKS 745
           G NY +EGP GNDIRRTNV  IR+ YRYET C EL LI + ++S
Sbjct: 817 GPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQS 860


>gi|29029552 cat eye syndrome critical region protein 1 isoform b
           [Homo sapiens]
          Length = 270

 Score = 37.7 bits (86), Expect = 0.039
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 5/114 (4%)

Query: 592 ISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFL--EYAKNPFLDFLQKGLMISLSTD 649
           I HG  L K P ++   +   IPI + P+SN  L L  +   +P    +  G  + +S+D
Sbjct: 141 IGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSD 200

Query: 650 DPMQFHFTKEPLMEEYAIAAQV--FKLSTCDMCEVARNSVLQCGISHEEKVKFL 701
           DP  F   K    + Y +   +   K     + ++A NS+    +   EK  F+
Sbjct: 201 DPAMFG-AKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFM 253


>gi|29029550 cat eye syndrome critical region protein 1 isoform a
           precursor [Homo sapiens]
          Length = 511

 Score = 37.7 bits (86), Expect = 0.039
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 5/114 (4%)

Query: 592 ISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFL--EYAKNPFLDFLQKGLMISLSTD 649
           I HG  L K P ++   +   IPI + P+SN  L L  +   +P    +  G  + +S+D
Sbjct: 382 IGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSD 441

Query: 650 DPMQFHFTKEPLMEEYAIAAQV--FKLSTCDMCEVARNSVLQCGISHEEKVKFL 701
           DP  F   K    + Y +   +   K     + ++A NS+    +   EK  F+
Sbjct: 442 DPAMFG-AKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFM 494


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 39/173 (22%), Positives = 68/173 (39%), Gaps = 27/173 (15%)

Query: 254  GPVKTYTHRRLKFLSSKF-QVHQMLNEMDELKELKNNPHRDFYNCRKVDTHI-------- 304
            G +KT    + + L  K  +V + LNEM++LKE   N         +  T I        
Sbjct: 862  GALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTL 921

Query: 305  -HAAACMNQKHLLRFIKKSYQIDADRV---VYSTKEKNL----TLKELFAKLKMHPYDLT 356
                    +K  L+ +++S QI+ D++   ++ T   N+     L+     LK H   + 
Sbjct: 922  EEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETIN 981

Query: 357  V--------DSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGE 401
                      S ++H    T +  D+F  K   VG  + +DL  K    +  +
Sbjct: 982  TLKSKISEEVSRNLHMEENTGETKDEFQQKM--VGIDKKQDLEAKNTQTLTAD 1032


>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
          Length = 4646

 Score = 31.2 bits (69), Expect = 3.7
 Identities = 34/98 (34%), Positives = 49/98 (50%), Gaps = 9/98 (9%)

Query: 249 ALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKEL---KNNPHRDFYNCRKVDTHIH 305
           AL A    K+   +  KFLS   QVH +L E   LKE    +    ++F +   ++  IH
Sbjct: 51  ALEAALEEKSALEQMRKFLSDP-QVHTVLVERSTLKEDVGDEGEEEKEFISYN-INIDIH 108

Query: 306 AAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTLKE 343
                N    L FIK++  IDAD+ V S++ + LTL E
Sbjct: 109 YGVKSNS---LAFIKRTPVIDADKPV-SSQLRVLTLSE 142


>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
          Length = 456

 Score = 30.4 bits (67), Expect = 6.3
 Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 5/40 (12%)

Query: 635 LDFLQKGLMISLSTDD--PMQFHFTKEPLMEEYAIAAQVF 672
           L++++KG  IS  TDD  P  FHF+KE     YA+    F
Sbjct: 222 LNYVEKGFQISNVTDDCKPKLFHFSKE---SAYALPTMAF 258


>gi|4504505 hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
          Length = 736

 Score = 30.0 bits (66), Expect = 8.2
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 364 AGRQTFQRF-DKFNDKYNPVGASELRDLY----LKTDNYINGE--YFATIIKEVGADLVE 416
           + R+  Q+F D    ++  + A   + +Y    L+T+ +  G   +F T ++E G  ++ 
Sbjct: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599

Query: 417 AKYQHAEPRLSIYGRSPDEWSKLSSWFVCNRI 448
             Y    P      ++P E  KL S FV   I
Sbjct: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEI 631


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,632,024
Number of Sequences: 37866
Number of extensions: 1300699
Number of successful extensions: 2760
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2737
Number of HSP's gapped (non-prelim): 16
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.