Guide to the Human Genome
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Search of human proteins with 4507451

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507451 trefoil factor 1 precursor [Homo sapiens]
         (84 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507451 trefoil factor 1 precursor [Homo sapiens]                  184   2e-47
gi|4885629 trefoil factor 2 precursor [Homo sapiens]                   74   2e-14
gi|48928027 trefoil factor 3 precursor [Homo sapiens]                  72   1e-13
gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens]       39   0.001
gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens]       39   0.001
gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens]       39   0.001
gi|221316699 maltase-glucoamylase [Homo sapiens]                       31   0.24 
gi|10863987 zona pellucida glycoprotein 4 preproprotein [Homo sa...    30   0.32 
gi|66348148 zona pellucida glycoprotein 1 [Homo sapiens]               30   0.32 
gi|157364974 sucrase-isomaltase [Homo sapiens]                         29   0.70 
gi|157909822 pragmin [Homo sapiens]                                    29   0.92 
gi|30089980 chordin [Homo sapiens]                                     28   2.0  
gi|110347463 human immunodeficiency virus type I enhancer bindin...    27   4.5  
gi|183979980 chemokine (C-C motif) receptor 2 isoform A [Homo sa...    26   5.9  
gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo sa...    26   5.9  
gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo sa...    26   5.9  
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]              26   5.9  
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]              26   5.9  
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]              26   5.9  
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]              26   5.9  
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]              26   5.9  
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]              26   5.9  
gi|21717816 solute carrier family 15, member 4 [Homo sapiens]          26   7.8  

>gi|4507451 trefoil factor 1 precursor [Homo sapiens]
          Length = 84

 Score =  184 bits (466), Expect = 2e-47
 Identities = 84/84 (100%), Positives = 84/84 (100%)

Query: 1  MATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDD 60
          MATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDD
Sbjct: 1  MATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDD 60

Query: 61 TVRGVPWCFYPNTIDVPPEEECEF 84
          TVRGVPWCFYPNTIDVPPEEECEF
Sbjct: 61 TVRGVPWCFYPNTIDVPPEEECEF 84


>gi|4885629 trefoil factor 2 precursor [Homo sapiens]
          Length = 129

 Score = 73.9 bits (180), Expect = 2e-14
 Identities = 30/72 (41%), Positives = 47/72 (65%), Gaps = 1/72 (1%)

Query: 1  MATMENKVICALVLVSMLAL-GTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFD 59
          M   + +++ AL+++ + AL G+   +  +   ++P  R NCGFPG+T  QC + GCCFD
Sbjct: 1  MGRRDAQLLAALLVLGLCALAGSEKPSPCQCSRLSPHNRTNCGFPGITSDQCFDNGCCFD 60

Query: 60 DTVRGVPWCFYP 71
           +V GVPWCF+P
Sbjct: 61 SSVTGVPWCFHP 72



 Score = 66.2 bits (160), Expect = 5e-12
 Identities = 22/62 (35%), Positives = 42/62 (67%), Gaps = 5/62 (8%)

Query: 23  LAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTIDVPPEEEC 82
           L + +++ C +   +R+NCG+PG++P +CA++ CCF + +  VPWCF+P ++     E+C
Sbjct: 73  LPKQESDQCVMEVSDRRNCGYPGISPEECASRKCCFSNFIFEVPWCFFPKSV-----EDC 127

Query: 83  EF 84
            +
Sbjct: 128 HY 129


>gi|48928027 trefoil factor 3 precursor [Homo sapiens]
          Length = 130

 Score = 71.6 bits (174), Expect = 1e-13
 Identities = 35/85 (41%), Positives = 45/85 (52%), Gaps = 9/85 (10%)

Query: 4   MENKVICALVLVSMLALGTLAEA----QTETCTVAPRERQNCGFPGVTPSQCANKGCCFD 59
           M  + +C L LV  L   + AE         C V  ++R +CG+P VTP +C N+GCCFD
Sbjct: 51  MAARALCMLGLVLALLSSSSAEEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFD 110

Query: 60  DTVRGVPWCFYPNTIDVPPEEECEF 84
             + GVPWCF P       E EC F
Sbjct: 111 SRIPGVPWCFKP-----LQEAECTF 130


>gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens]
          Length = 952

 Score = 38.5 bits (88), Expect = 0.001
 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 8/49 (16%)

Query: 31  CTVAPRERQNCG-FPGVTPSQCANKGCCFDDTVRGV-------PWCFYP 71
           C V P  R +C     +T  QC  +GCC+    +G+       PWCF+P
Sbjct: 82  CDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP 130


>gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens]
          Length = 952

 Score = 38.5 bits (88), Expect = 0.001
 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 8/49 (16%)

Query: 31  CTVAPRERQNCG-FPGVTPSQCANKGCCFDDTVRGV-------PWCFYP 71
           C V P  R +C     +T  QC  +GCC+    +G+       PWCF+P
Sbjct: 82  CDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP 130


>gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens]
          Length = 952

 Score = 38.5 bits (88), Expect = 0.001
 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 8/49 (16%)

Query: 31  CTVAPRERQNCG-FPGVTPSQCANKGCCFDDTVRGV-------PWCFYP 71
           C V P  R +C     +T  QC  +GCC+    +G+       PWCF+P
Sbjct: 82  CDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP 130


>gi|221316699 maltase-glucoamylase [Homo sapiens]
          Length = 1857

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 4/37 (10%)

Query: 37  ERQNCGFPGVTPSQ--CANKGCCFDDT-VRGVPWCFY 70
           ER NC  P   P++  C  +GCC++      VPWC+Y
Sbjct: 97  ERINC-IPDQPPTKATCDQRGCCWNPQGAVSVPWCYY 132


>gi|10863987 zona pellucida glycoprotein 4 preproprotein [Homo
           sapiens]
          Length = 540

 Score = 30.4 bits (67), Expect = 0.32
 Identities = 17/58 (29%), Positives = 25/58 (43%), Gaps = 3/58 (5%)

Query: 28  TETCTVAP-RERQNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTIDVPPEEECEF 84
           T+ C   P R+R  C    ++   C   GCC+      V  C+Y NT+ +    E  F
Sbjct: 140 TDWCDSIPARDRLPCAPSPISRGDCEGLGCCYSS--EEVNSCYYGNTVTLHCTREGHF 195


>gi|66348148 zona pellucida glycoprotein 1 [Homo sapiens]
          Length = 638

 Score = 30.4 bits (67), Expect = 0.32
 Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 3/48 (6%)

Query: 29  ETCTVAPRERQNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTIDV 76
           E C VA      C     +   C   GCC+D+T R VP C+Y NT  V
Sbjct: 234 EQCQVASGHLP-CIVRRTSKEACQQAGCCYDNT-REVP-CYYGNTATV 278


>gi|157364974 sucrase-isomaltase [Homo sapiens]
          Length = 1827

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 15/38 (39%), Positives = 24/38 (63%), Gaps = 8/38 (21%)

Query: 38  RQNCGFPGVTPSQ--CANKGCC---FDDTVRGVPWCFY 70
           R NC  P   P++  CA +GCC   ++D++  +PWCF+
Sbjct: 74  RINC-IPEQFPTEGICAQRGCCWRPWNDSL--IPWCFF 108


>gi|157909822 pragmin [Homo sapiens]
          Length = 1402

 Score = 28.9 bits (63), Expect = 0.92
 Identities = 11/18 (61%), Positives = 15/18 (83%)

Query: 34  APRERQNCGFPGVTPSQC 51
           AP ++Q+ G PGVTPS+C
Sbjct: 371 APEKQQDPGCPGVTPSRC 388


>gi|30089980 chordin [Homo sapiens]
          Length = 955

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 15/52 (28%), Positives = 24/52 (46%)

Query: 8   VICALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFD 59
           VIC  V+    +     +A  + C V P ++     PG+  S+   +GC FD
Sbjct: 736 VICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFD 787


>gi|110347463 human immunodeficiency virus type I enhancer binding
           protein 2 [Homo sapiens]
          Length = 2446

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 9/22 (40%), Positives = 14/22 (63%)

Query: 58  FDDTVRGVPWCFYPNTIDVPPE 79
           FD+ + G    FYP T+ +PP+
Sbjct: 566 FDERMTGSDDVFYPGTVGIPPQ 587


>gi|183979980 chemokine (C-C motif) receptor 2 isoform A [Homo
           sapiens]
          Length = 374

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 9/20 (45%), Positives = 13/20 (65%)

Query: 31  CTVAPRERQNCGFPGVTPSQ 50
           C +AP ++  CG PGV P +
Sbjct: 322 CRIAPLQKPVCGGPGVRPGK 341


>gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo
            sapiens]
          Length = 2316

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 4/42 (9%)

Query: 2    ATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGF 43
            A M+ KVI  +V  +     TL +AQ E+C +  R+R+N  F
Sbjct: 1250 AAMDEKVIGKVVDQAC----TLEKAQVESCQLNNRDRRNVDF 1287


>gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo
            sapiens]
          Length = 2342

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 4/42 (9%)

Query: 2    ATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGF 43
            A M+ KVI  +V  +     TL +AQ E+C +  R+R+N  F
Sbjct: 1276 AAMDEKVIGKVVDQAC----TLEKAQVESCQLNNRDRRNVDF 1313


>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2852

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 13/69 (18%)

Query: 27  QTETCTVAPRER----QNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTI-------D 75
           Q   CTV  +E+      C      P+ C  +  C D  +  V  C+ PN +        
Sbjct: 339 QLRQCTVHCKEKAFTYNEC--IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCV 396

Query: 76  VPPEEECEF 84
            P E  CEF
Sbjct: 397 APAECPCEF 405


>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2924

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 13/69 (18%)

Query: 27  QTETCTVAPRER----QNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTI-------D 75
           Q   CTV  +E+      C      P+ C  +  C D  +  V  C+ PN +        
Sbjct: 411 QLRQCTVHCKEKAFTYNEC--IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCV 468

Query: 76  VPPEEECEF 84
            P E  CEF
Sbjct: 469 APAECPCEF 477


>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 13/69 (18%)

Query: 27  QTETCTVAPRER----QNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTI-------D 75
           Q   CTV  +E+      C      P+ C  +  C D  +  V  C+ PN +        
Sbjct: 339 QLRQCTVHCKEKAFTYNEC--IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCV 396

Query: 76  VPPEEECEF 84
            P E  CEF
Sbjct: 397 APAECPCEF 405


>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 13/69 (18%)

Query: 27  QTETCTVAPRER----QNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTI-------D 75
           Q   CTV  +E+      C      P+ C  +  C D  +  V  C+ PN +        
Sbjct: 411 QLRQCTVHCKEKAFTYNEC--IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCV 468

Query: 76  VPPEEECEF 84
            P E  CEF
Sbjct: 469 APAECPCEF 477


>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 13/69 (18%)

Query: 27  QTETCTVAPRER----QNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTI-------D 75
           Q   CTV  +E+      C      P+ C  +  C D  +  V  C+ PN +        
Sbjct: 339 QLRQCTVHCKEKAFTYNEC--IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCV 396

Query: 76  VPPEEECEF 84
            P E  CEF
Sbjct: 397 APAECPCEF 405


>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 13/69 (18%)

Query: 27  QTETCTVAPRER----QNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTI-------D 75
           Q   CTV  +E+      C      P+ C  +  C D  +  V  C+ PN +        
Sbjct: 411 QLRQCTVHCKEKAFTYNEC--IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCV 468

Query: 76  VPPEEECEF 84
            P E  CEF
Sbjct: 469 APAECPCEF 477


>gi|21717816 solute carrier family 15, member 4 [Homo sapiens]
          Length = 577

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 19/55 (34%), Positives = 21/55 (38%), Gaps = 4/55 (7%)

Query: 11  ALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDDTVRGV 65
           AL L+ MLA   LA   T           NC  PG  P   A   CC   T  G+
Sbjct: 111 ALYLLGMLAFPLLAAPATRAALCGSARLLNCTAPG--PDAAAR--CCSPATFAGL 161


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,767,324
Number of Sequences: 37866
Number of extensions: 152135
Number of successful extensions: 367
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 356
Number of HSP's gapped (non-prelim): 24
length of query: 84
length of database: 18,247,518
effective HSP length: 56
effective length of query: 28
effective length of database: 16,127,022
effective search space: 451556616
effective search space used: 451556616
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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