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Search of human proteins with 4507379
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507379 TATA box binding protein [Homo sapiens]
(339 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507379 TATA box binding protein [Homo sapiens] 667 0.0
gi|39930602 TATA box binding protein like 2 [Homo sapiens] 369 e-102
gi|4759234 TBP-like 1 [Homo sapiens] 137 1e-32
gi|33286444 mastermind-like 2 [Homo sapiens] 94 1e-19
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 88 1e-17
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 88 1e-17
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 88 1e-17
gi|110347429 mediator complex subunit 12 [Homo sapiens] 88 1e-17
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 79 8e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 78 1e-14
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 77 3e-14
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 77 3e-14
gi|40354197 THAP domain containing 11 [Homo sapiens] 77 3e-14
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 72 5e-13
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 72 5e-13
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 72 5e-13
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 72 9e-13
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 72 9e-13
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 70 3e-12
gi|189491748 ataxin 1 [Homo sapiens] 70 4e-12
gi|51479158 ataxin 1 [Homo sapiens] 70 4e-12
gi|56549696 E1A binding protein p400 [Homo sapiens] 70 4e-12
gi|38158015 mastermind-like 3 [Homo sapiens] 69 5e-12
gi|226246533 TOX high mobility group box family member 3 isoform... 67 2e-11
gi|226054295 TOX high mobility group box family member 3 isoform... 67 2e-11
gi|55956910 meningioma 1 [Homo sapiens] 67 2e-11
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 67 2e-11
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s... 64 1e-10
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 64 1e-10
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 64 1e-10
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 667 bits (1720), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQ 60
MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQ
Sbjct: 1 MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQ 60
Query: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
Query: 121 LFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDL 180
LFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDL
Sbjct: 121 LFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDL 180
Query: 181 KTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARV 240
KTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARV
Sbjct: 181 KTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARV 240
Query: 241 VQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRI 300
VQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRI
Sbjct: 241 VQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRI 300
Query: 301 VLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT 339
VLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
Sbjct: 301 VLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT 339
>gi|39930602 TATA box binding protein like 2 [Homo sapiens]
Length = 375
Score = 369 bits (948), Expect = e-102
Identities = 204/350 (58%), Positives = 237/350 (67%), Gaps = 21/350 (6%)
Query: 1 MDQNNS-LPPYAQGLASPQGAMTPGIPIFSPMMPYGTGL------------TPQPIQNTN 47
M+Q + L Y A+ G P P+FSP++PY + P+ + +
Sbjct: 33 MEQEETYLELYLDQCAAQDGLAPPRSPLFSPVVPYDMYILNASNPDTAFNSNPEVKETSG 92
Query: 48 SLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTS 107
S ++ + Q+ + Q + + ++ + Q Q + +Q V S S
Sbjct: 93 DFSSVDLSFLPDEVTQENKDQPVISKHETEENSESQSPQSRLPSPSEQDVGLGLNSSSLS 152
Query: 108 QQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQN 167
+Q L T + P P + +TP+TP TP SE GIVPQLQN
Sbjct: 153 NSHSQ--------LHPGDTDSVQPSPEKPNSDSLSLASITPMTPMTPISECCGIVPQLQN 204
Query: 168 IVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSE 227
IVSTVNL CKLDLK IAL A+NAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSE
Sbjct: 205 IVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSE 264
Query: 228 EQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPEL 287
EQSRLAARKYARVVQKLGFPA+FLDFKIQNMVGSCDV+FPIRLEGLVLTHQQFSSYEPEL
Sbjct: 265 EQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPEL 324
Query: 288 FPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRK 337
FPGLIYRM+KPRIVLLIFVSGKVVLTGAK R+EIYEAFENIYPILKGF+K
Sbjct: 325 FPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFKK 374
>gi|4759234 TBP-like 1 [Homo sapiens]
Length = 186
Score = 137 bits (345), Expect = 1e-32
Identities = 73/173 (42%), Positives = 106/173 (61%), Gaps = 2/173 (1%)
Query: 165 LQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGA 224
+ N+V C L+L+ IAL N Y + V+M++R+PR TA I+SSGK++CTGA
Sbjct: 13 ITNVVCVFRTRCHLNLRKIALEGANVIYK-RDVGKVLMKLRKPRITATIWSSGKIICTGA 71
Query: 225 KSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYE 284
SEE+++ AR+ AR +QKLGF F DFK+ N++ C++ F IRL ++ +SYE
Sbjct: 72 TSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYE 131
Query: 285 PELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRK 337
PEL P + YR+ R L IF +G + +TG V+A + A E IYP + RK
Sbjct: 132 PELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKA-VATAVEQIYPFVFESRK 183
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 94.4 bits (233), Expect = 1e-19
Identities = 65/142 (45%), Positives = 73/142 (51%), Gaps = 24/142 (16%)
Query: 16 SPQGAMTPGIPIFSPMMPYGTGLTPQ------PIQNTNSL-SILEEQQRQQQQQQQQQQQ 68
+P AM P P+ + + Q P QN SL ++QQ+QQQQQQQQQQQ
Sbjct: 544 NPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQ 603
Query: 69 QQQQQQQQQQQQQQQQQQ-----------------QQQQQQQQQAVAAAAVQQSTSQQAT 111
QQQQQQQQQQQQQQQQQQ QQQQQQQQQ QQ QQ
Sbjct: 604 QQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQ 663
Query: 112 QGTSGQAPQLFHSQTLTTAPLP 133
Q S Q Q SQ L +PLP
Sbjct: 664 QQPSSQPAQSLPSQPLLRSPLP 685
Score = 67.0 bits (162), Expect = 2e-11
Identities = 50/141 (35%), Positives = 66/141 (46%), Gaps = 10/141 (7%)
Query: 44 QNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103
Q S + QQ+QQQQQQQQQQQQQQQQQQQQQQQQ Q Q Q + +Q
Sbjct: 628 QQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ 687
Query: 104 QS--TSQQATQGTSGQAPQLFHSQTLTTAPLPG-TTPLYPSPMTPMTPITPATPASESSG 160
Q Q Q +G Q+ Q + G T PSP P + + SG
Sbjct: 688 QKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSP-------NPCSNPNTGSG 740
Query: 161 IVPQLQNIVSTVNLGCKLDLK 181
+ Q++++ +G K L+
Sbjct: 741 YMNSQQSLLNQQLMGKKQTLQ 761
Score = 32.7 bits (73), Expect = 0.48
Identities = 53/212 (25%), Positives = 81/212 (38%), Gaps = 16/212 (7%)
Query: 35 GTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----QQ 89
G +P P N N+ S Q+ QQ ++Q Q+Q +Q+QQ QQQ ++
Sbjct: 724 GPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEK 783
Query: 90 QQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPI 149
Q Q + + + P +S +T L L +P++ T +
Sbjct: 784 IAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQAL-ANPVSTHTIL 842
Query: 150 TP-ATPASESSGI-VPQLQNIVSTV----NLGCKLD---LKTIALRARNAEYNPKRFAAV 200
TP ++ S S G +P L V + NL C T + + NPK+ A
Sbjct: 843 TPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLAN 902
Query: 201 IMRIREPRTTALIFSSGKMVCT-GAKSEEQSR 231
PR L S+ V T GA S S+
Sbjct: 903 QNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQ 934
Score = 29.3 bits (64), Expect = 5.3
Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 66 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQ---APQLF 122
Q+ QQ +Q +QQ + QQ QQQ Q +A+ S + G GQ F
Sbjct: 428 QEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAG--PSPGPFGQEKIPSPSF 485
Query: 123 HSQTLT--TAPLPG 134
QT + ++P+PG
Sbjct: 486 GQQTFSPQSSPMPG 499
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 88.2 bits (217), Expect = 1e-17
Identities = 50/76 (65%), Positives = 54/76 (71%), Gaps = 2/76 (2%)
Query: 52 LEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQAT 111
L+ Q+QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ A +Q QQ
Sbjct: 148 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 207
Query: 112 QGTSGQAPQLFHSQTL 127
Q + Q QL Q L
Sbjct: 208 QQLAAQ--QLVFQQQL 221
Score = 87.0 bits (214), Expect = 2e-17
Identities = 61/119 (51%), Positives = 68/119 (57%), Gaps = 17/119 (14%)
Query: 49 LSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------QQQQQQQA 96
L +L++QQ+QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQ
Sbjct: 148 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 207
Query: 97 VAAAAVQQSTSQQATQGTSGQAPQLFHS---QTLTTAPLPGTTPLYPSPMTPMTPITPA 152
AA Q QQ Q Q Q S Q L + P PG L P P ++PA
Sbjct: 208 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIP-PGQAAL-PVQSLPQAGLSPA 264
Score = 75.5 bits (184), Expect = 6e-14
Identities = 48/95 (50%), Positives = 58/95 (61%), Gaps = 12/95 (12%)
Query: 38 LTPQPIQ---NTNSLSILEEQQRQQ---QQQQQ------QQQQQQQQQQQQQQQQQQQQQ 85
L+PQ +Q +L++QQ Q+ +QQ+Q QQQQQQQQQQQQQQQQQQQQQ
Sbjct: 113 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 172
Query: 86 QQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
QQQQQQQQQQ QQ +QA + Q Q
Sbjct: 173 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 207
Score = 71.6 bits (174), Expect = 9e-13
Identities = 60/151 (39%), Positives = 68/151 (45%), Gaps = 26/151 (17%)
Query: 7 LPPYAQGLASPQGAMTPG---IPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQ---QQ 60
L GL SP+ + +P+ MM +TPQ +Q +L QQ Q QQ
Sbjct: 66 LQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQV-ITPQQMQQILQQQVLSPQQLQALLQQ 124
Query: 61 QQ----QQQQQQ---------------QQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAA 101
QQ QQQQ Q QQQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 125 QQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 184
Query: 102 VQQSTSQQATQGTSGQAPQLFHSQTLTTAPL 132
QQ Q + Q Q Q L L
Sbjct: 185 QQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215
Score = 30.0 bits (66), Expect = 3.1
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 13/77 (16%)
Query: 53 EEQQRQQQQQQ-------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAA 99
E+QQ+QQQQQQ Q QQ QQQQ Q+Q Q Q++
Sbjct: 199 EQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQ 258
Query: 100 AAVQQSTSQQATQGTSG 116
A + + QQ + +G
Sbjct: 259 AGLSPAEIQQLWKEVTG 275
Score = 28.5 bits (62), Expect = 9.0
Identities = 21/122 (17%), Positives = 47/122 (38%), Gaps = 19/122 (15%)
Query: 41 QPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAA 100
Q +++ N+ L+++ Q + Q Q QQ + Q +++++ Q + + +
Sbjct: 362 QFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPK 421
Query: 101 AVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSG 160
+ +S ++ +PQ P TP TP P TP ++
Sbjct: 422 PLNLVSSVTMSKNMLETSPQSL-------------------PQTPTTPTAPVTPITQGPS 462
Query: 161 IV 162
++
Sbjct: 463 VI 464
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 88.2 bits (217), Expect = 1e-17
Identities = 50/76 (65%), Positives = 54/76 (71%), Gaps = 2/76 (2%)
Query: 52 LEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQAT 111
L+ Q+QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ A +Q QQ
Sbjct: 56 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 115
Query: 112 QGTSGQAPQLFHSQTL 127
Q + Q QL Q L
Sbjct: 116 QQLAAQ--QLVFQQQL 129
Score = 87.0 bits (214), Expect = 2e-17
Identities = 61/119 (51%), Positives = 68/119 (57%), Gaps = 17/119 (14%)
Query: 49 LSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------QQQQQQQA 96
L +L++QQ+QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQ
Sbjct: 56 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 115
Query: 97 VAAAAVQQSTSQQATQGTSGQAPQLFHS---QTLTTAPLPGTTPLYPSPMTPMTPITPA 152
AA Q QQ Q Q Q S Q L + P PG L P P ++PA
Sbjct: 116 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIP-PGQAAL-PVQSLPQAGLSPA 172
Score = 75.5 bits (184), Expect = 6e-14
Identities = 48/95 (50%), Positives = 58/95 (61%), Gaps = 12/95 (12%)
Query: 38 LTPQPIQ---NTNSLSILEEQQRQQ---QQQQQ------QQQQQQQQQQQQQQQQQQQQQ 85
L+PQ +Q +L++QQ Q+ +QQ+Q QQQQQQQQQQQQQQQQQQQQQ
Sbjct: 21 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 80
Query: 86 QQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
QQQQQQQQQQ QQ +QA + Q Q
Sbjct: 81 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 115
Score = 62.4 bits (150), Expect = 6e-10
Identities = 44/106 (41%), Positives = 48/106 (45%), Gaps = 23/106 (21%)
Query: 38 LTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQ-----------------------QQ 74
+TPQ I IL++Q QQ Q QQQQ QQ
Sbjct: 2 MTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQ 61
Query: 75 QQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
QQQQQQQQQQQQQQQQQQQQQ QQ QQ Q QA +
Sbjct: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKE 107
Score = 62.4 bits (150), Expect = 6e-10
Identities = 47/118 (39%), Positives = 51/118 (43%), Gaps = 24/118 (20%)
Query: 38 LTPQPIQNTNSLSILEEQQRQQQQQQQQQQQ-----------------------QQQQQQ 74
+TPQ +Q +L QQ Q QQQQ QQQQQQ
Sbjct: 7 ITPQQMQQILQQQVLSPQQLQALLQQQQAV-MLQQQQLQEFYKKQQEQLHLQLLQQQQQQ 65
Query: 75 QQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPL 132
QQQQQQQQQQQQQQQQQQQQQ QQ Q + Q Q Q L L
Sbjct: 66 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 123
Score = 30.0 bits (66), Expect = 3.1
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 13/77 (16%)
Query: 53 EEQQRQQQQQQ-------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAA 99
E+QQ+QQQQQQ Q QQ QQQQ Q+Q Q Q++
Sbjct: 107 EQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQ 166
Query: 100 AAVQQSTSQQATQGTSG 116
A + + QQ + +G
Sbjct: 167 AGLSPAEIQQLWKEVTG 183
Score = 28.5 bits (62), Expect = 9.0
Identities = 21/122 (17%), Positives = 47/122 (38%), Gaps = 19/122 (15%)
Query: 41 QPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAA 100
Q +++ N+ L+++ Q + Q Q QQ + Q +++++ Q + + +
Sbjct: 270 QFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPK 329
Query: 101 AVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSG 160
+ +S ++ +PQ P TP TP P TP ++
Sbjct: 330 PLNLVSSVTMSKNMLETSPQSL-------------------PQTPTTPTAPVTPITQGPS 370
Query: 161 IV 162
++
Sbjct: 371 VI 372
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 88.2 bits (217), Expect = 1e-17
Identities = 50/76 (65%), Positives = 54/76 (71%), Gaps = 2/76 (2%)
Query: 52 LEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQAT 111
L+ Q+QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ A +Q QQ
Sbjct: 173 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232
Query: 112 QGTSGQAPQLFHSQTL 127
Q + Q QL Q L
Sbjct: 233 QQLAAQ--QLVFQQQL 246
Score = 87.0 bits (214), Expect = 2e-17
Identities = 61/119 (51%), Positives = 68/119 (57%), Gaps = 17/119 (14%)
Query: 49 LSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------QQQQQQQA 96
L +L++QQ+QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQ
Sbjct: 173 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232
Query: 97 VAAAAVQQSTSQQATQGTSGQAPQLFHS---QTLTTAPLPGTTPLYPSPMTPMTPITPA 152
AA Q QQ Q Q Q S Q L + P PG L P P ++PA
Sbjct: 233 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIP-PGQAAL-PVQSLPQAGLSPA 289
Score = 75.5 bits (184), Expect = 6e-14
Identities = 48/95 (50%), Positives = 58/95 (61%), Gaps = 12/95 (12%)
Query: 38 LTPQPIQ---NTNSLSILEEQQRQQ---QQQQQ------QQQQQQQQQQQQQQQQQQQQQ 85
L+PQ +Q +L++QQ Q+ +QQ+Q QQQQQQQQQQQQQQQQQQQQQ
Sbjct: 138 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 197
Query: 86 QQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
QQQQQQQQQQ QQ +QA + Q Q
Sbjct: 198 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232
Score = 62.8 bits (151), Expect = 4e-10
Identities = 51/134 (38%), Positives = 57/134 (42%), Gaps = 25/134 (18%)
Query: 22 TPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQ------------- 68
T +P+ MM +TPQ +Q +L QQ Q QQQQ
Sbjct: 109 TFAVPVSVAMMTPQV-ITPQQMQQILQQQVLSPQQLQALLQQQQAV-MLQQQQLQEFYKK 166
Query: 69 ----------QQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQA 118
QQQQQQQQQQQQQQQQQQQQQQQQQQQ QQ Q + Q
Sbjct: 167 QQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ 226
Query: 119 PQLFHSQTLTTAPL 132
Q Q L L
Sbjct: 227 QQQQQQQQLAAQQL 240
Score = 47.0 bits (110), Expect = 2e-05
Identities = 38/111 (34%), Positives = 42/111 (37%), Gaps = 23/111 (20%)
Query: 33 PYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQ------------ 80
P+ T P + I +Q +Q QQQ QQ Q QQQQ
Sbjct: 106 PHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYK 165
Query: 81 -----------QQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
QQQQQQQQQQQQQQQ QQ QQ Q Q Q
Sbjct: 166 KQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 216
Score = 30.0 bits (66), Expect = 3.1
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 13/77 (16%)
Query: 53 EEQQRQQQQQQ-------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAA 99
E+QQ+QQQQQQ Q QQ QQQQ Q+Q Q Q++
Sbjct: 224 EQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQ 283
Query: 100 AAVQQSTSQQATQGTSG 116
A + + QQ + +G
Sbjct: 284 AGLSPAEIQQLWKEVTG 300
Score = 28.5 bits (62), Expect = 9.0
Identities = 21/122 (17%), Positives = 47/122 (38%), Gaps = 19/122 (15%)
Query: 41 QPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAA 100
Q +++ N+ L+++ Q + Q Q QQ + Q +++++ Q + + +
Sbjct: 387 QFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPK 446
Query: 101 AVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSG 160
+ +S ++ +PQ P TP TP P TP ++
Sbjct: 447 PLNLVSSVTMSKNMLETSPQSL-------------------PQTPTTPTAPVTPITQGPS 487
Query: 161 IV 162
++
Sbjct: 488 VI 489
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 87.8 bits (216), Expect = 1e-17
Identities = 72/173 (41%), Positives = 87/173 (50%), Gaps = 23/173 (13%)
Query: 8 PPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQ-NTNSLSILEEQQRQQQQQQ--Q 64
P Y GL S Q + +PM+ T ++ Q +Q S +IL EQQ+QQQQQQ Q
Sbjct: 2004 PTYGHGLTSTQRFSHQTLQQ-TPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQ 2062
Query: 65 QQQQQQQQQQQQQQ----QQQQQQ---QQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQ 117
QQQQQQQQQQQQQQ QQQQQQ QQQQQQQQQQQ QQ QQ Q Q
Sbjct: 2063 QQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ-------QQQQQQQQQQQQQQQ 2115
Query: 118 APQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVS 170
Q Q P P + P + T +++ +V QLQ +S
Sbjct: 2116 HQQQQQQQAAPPQPQPQSQPQFQRQGLQQT-----QQQQQTAALVRQLQQQLS 2163
Score = 58.9 bits (141), Expect = 6e-09
Identities = 34/64 (53%), Positives = 39/64 (60%), Gaps = 4/64 (6%)
Query: 53 EEQQRQQQQQQQQQQQQQQ----QQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQ 108
++QQ+QQQQQQ QQQQQQQ Q Q Q Q Q Q+Q QQ QQQQQ A +QQ S
Sbjct: 2105 QQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSN 2164
Query: 109 QATQ 112
Q
Sbjct: 2165 TQPQ 2168
Score = 53.1 bits (126), Expect = 3e-07
Identities = 29/63 (46%), Positives = 37/63 (58%)
Query: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
++QQ+Q QQQQQQQ Q Q Q Q Q Q+Q QQ QQQQQ A+ QQ ++ Q
Sbjct: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
Query: 113 GTS 115
T+
Sbjct: 2170 STN 2172
Score = 35.4 bits (80), Expect = 0.073
Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 5/167 (2%)
Query: 3 QNNSLPPYAQGLASPQGA--MTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQ 60
+ S+ Y Q P G + P P+ PM T T + T ++ + +
Sbjct: 1835 RQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYK 1894
Query: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
+QQQ Q Q+ +QQ QQ Q Q Q +++ TSQ T S Q
Sbjct: 1895 TSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQ 1954
Query: 121 LFHSQTLTTAPLPGTTPLYPS--PMTPMTPITPATPASE-SSGIVPQ 164
T P ++ Y S P T T + P + SG V Q
Sbjct: 1955 QHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQ 2001
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 78.6 bits (192), Expect = 8e-15
Identities = 71/196 (36%), Positives = 83/196 (42%), Gaps = 32/196 (16%)
Query: 4 NNSLPPYAQGLASPQGAMTP---GIPIFSPMMPYGTGLTP----QPIQNTNSLSILEEQQ 56
N L P AS AM P G+ I P G+ P QP+ ++ Q
Sbjct: 200 NPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQ 259
Query: 57 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQ-------- 108
QQQQQQQQQQQQQQQQQQQQQQQQQ Q + QQ QQQQ + +Q
Sbjct: 260 LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWN 319
Query: 109 QATQGTSGQAPQLFHSQTLTT------APLPG----TTPLYPSPMTPMTPITPATP---- 154
Q G P T+T APLPG PS T TP P P
Sbjct: 320 QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFG 379
Query: 155 ---ASESSGIVPQLQN 167
AS++ PQ+ N
Sbjct: 380 SQQASQAHTNFPQMSN 395
Score = 49.3 bits (116), Expect = 5e-06
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 18/132 (13%)
Query: 38 LTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAV 97
+ PQ +Q+ +QQ Q Q QQQQ Q Q QQQQQQQQQ QQ
Sbjct: 986 MPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKS 1045
Query: 98 AAAAVQQST----------SQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMT 147
V Q+ SQ+ SG P + L G + PSP
Sbjct: 1046 VRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVM--------VSLQGPASVPPSPDKQRM 1097
Query: 148 PITPATPASESS 159
P+ TP +S
Sbjct: 1098 PMPVNTPLGSNS 1109
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 77.8 bits (190), Expect = 1e-14
Identities = 51/110 (46%), Positives = 59/110 (53%), Gaps = 1/110 (0%)
Query: 18 QGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQ 77
QG+M G+ + +G Q SL L++QQ+ QQQQQ QQQQQQQ QQQQQ
Sbjct: 3867 QGSMA-GLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQ 3925
Query: 78 QQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTL 127
QQQQ QQQQQQQQ QQQ QQ QQ Q Q Q Q +
Sbjct: 3926 LQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQM 3975
Score = 77.8 bits (190), Expect = 1e-14
Identities = 49/109 (44%), Positives = 57/109 (52%)
Query: 41 QPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAA 100
Q +Q L ++ Q+QQQQQ QQQQQ QQQQ QQQQQQQQ QQQQQQQ QQQQ
Sbjct: 3898 QQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQ 3957
Query: 101 AVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPI 149
QQ Q Q Q L S+TL + + P P P+
Sbjct: 3958 QQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPL 4006
Score = 69.7 bits (169), Expect = 4e-12
Identities = 39/71 (54%), Positives = 44/71 (61%)
Query: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
++ Q+QQQQQ QQQQQQ QQQQQQQQQQ QQQQQQQQ Q+ + QQ QQ
Sbjct: 3938 QQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVAL 3997
Query: 113 GTSGQAPQLFH 123
G A L H
Sbjct: 3998 GPGMPAKPLQH 4008
Score = 67.4 bits (163), Expect = 2e-11
Identities = 51/131 (38%), Positives = 63/131 (48%), Gaps = 21/131 (16%)
Query: 54 EQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-------------QQQQQQQQAVAAA 100
+QQ+QQQ QQQQQQ QQQQQQQQQQ QQQQQQQQ QQQQQQQ A+
Sbjct: 3941 QQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPG 4000
Query: 101 AVQQSTSQQATQGTSGQAPQLFHSQTLTTAP------LPGTTPLYPSPMTPMTPITPATP 154
+ ++ G G L + T P G + P+ T TP +
Sbjct: 4001 MPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGT--TPESM 4058
Query: 155 ASESSGIVPQL 165
A+E + P L
Sbjct: 4059 ATEPGEVKPSL 4069
Score = 59.3 bits (142), Expect = 5e-09
Identities = 60/194 (30%), Positives = 69/194 (35%), Gaps = 72/194 (37%)
Query: 4 NNSLPPYAQGL-------------------ASPQGAMTPG-IPIFSPMMPYGTG------ 37
N +L P QGL PQG + P + + P G
Sbjct: 3766 NQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHR 3825
Query: 38 ----------LTPQPIQNTNSL---SILEEQQRQQQQQQQQQ------------------ 66
+PQ Q L ++ QQ+QQQQQ QQQ
Sbjct: 3826 QVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSG 3885
Query: 67 ---------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQAT 111
QQQQQ QQQQQ QQQQQQQ QQQQQ QQQ + QQ QQ
Sbjct: 3886 QPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQ 3945
Query: 112 QGTSGQAPQLFHSQ 125
Q Q QL Q
Sbjct: 3946 QQLQQQQQQLQQQQ 3959
Score = 52.4 bits (124), Expect = 6e-07
Identities = 29/68 (42%), Positives = 42/68 (61%), Gaps = 4/68 (5%)
Query: 42 PIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQ----QQQQQQQQQQQQQQQQQQQQQAV 97
P + L ++ EQQ + Q+Q Q ++QQ++ + + +QQQQQQQQQQQQQQ AV
Sbjct: 3557 PEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAV 3616
Query: 98 AAAAVQQS 105
A + QS
Sbjct: 3617 LALSPSQS 3624
Score = 52.4 bits (124), Expect = 6e-07
Identities = 46/133 (34%), Positives = 53/133 (39%), Gaps = 20/133 (15%)
Query: 11 AQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQ 70
A LA P G PG + P +L+E+Q Q QQQ+ Q Q+
Sbjct: 3689 AGSLAGPSGGFFPGNLALRSLGP--------------DSRLLQERQLQLQQQRMQLAQKL 3734
Query: 71 QQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTA 130
QQQQQQQQQQQ Q QQQQQQ T+Q G P H Q L
Sbjct: 3735 QQQQQQQQQQQHLLGQVAIQQQQQQGPGV-----QTNQALGPKPQGLMPPSSH-QGLLVQ 3788
Query: 131 PLPGTTPLYPSPM 143
L P P M
Sbjct: 3789 QLSPQPPQGPQGM 3801
Score = 48.5 bits (114), Expect = 8e-06
Identities = 48/133 (36%), Positives = 54/133 (40%), Gaps = 24/133 (18%)
Query: 19 GAMTPGIPIFSPMMPYGTGLT-PQPIQNTNSLS---ILEEQQRQQQQQQQQQ-------- 66
GA+ P P +M L+ PQ Q L ++ QQ+QQQQQ QQQ
Sbjct: 3816 GALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSH 3875
Query: 67 -QQQQQQQQQQ-----------QQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114
QQ Q QQ QQQQQ QQQQQ QQQQ QQ QQ Q
Sbjct: 3876 LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQ 3935
Query: 115 SGQAPQLFHSQTL 127
Q Q Q L
Sbjct: 3936 QQQQLQQQQQQQL 3948
Score = 42.7 bits (99), Expect = 5e-04
Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 6/118 (5%)
Query: 32 MPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 91
+P G + + S + E + + ++++ Q++QQ Q Q QQQQQQQQ
Sbjct: 3222 LPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQ 3281
Query: 92 QQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGT-TPLYPSPMTPMTP 148
Q A Q + G +P L SQ + L G P P P+ P P
Sbjct: 3282 QHSLLSAPGPAQAMSLPH-----EGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQP 3334
Score = 42.7 bits (99), Expect = 5e-04
Identities = 27/66 (40%), Positives = 36/66 (54%), Gaps = 11/66 (16%)
Query: 63 QQQQQQQQQQQQQQQQQQQ-----------QQQQQQQQQQQQQQAVAAAAVQQSTSQQAT 111
+QQ + Q+Q Q ++QQ++ QQQQQQQQQQQQQQ A A+ S S +
Sbjct: 3569 EQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLL 3628
Query: 112 QGTSGQ 117
GQ
Sbjct: 3629 TKLPGQ 3634
Score = 42.4 bits (98), Expect = 6e-04
Identities = 45/171 (26%), Positives = 63/171 (36%), Gaps = 7/171 (4%)
Query: 3 QNNSLP-PYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQ 61
QNN+ P P G G PG+ I + L +N + +QQ+Q Q
Sbjct: 4165 QNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQA 4224
Query: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQAVAAAAVQQSTSQQATQGTSGQ 117
Q+Q QQ Q +Q Q+ Q Q Q Q Q Q+ G Q
Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQ 4284
Query: 118 APQLFHSQ--TLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQ 166
P + L+T P+ G P P +P P P+ S SS + + Q
Sbjct: 4285 GPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQ 4335
Score = 42.0 bits (97), Expect = 8e-04
Identities = 28/82 (34%), Positives = 36/82 (43%)
Query: 70 QQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTT 129
Q++Q Q QQQ+ Q Q+ QQQQQQQQ Q + QQ QG Q Q +
Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGL 3776
Query: 130 APLPGTTPLYPSPMTPMTPITP 151
P L ++P P P
Sbjct: 3777 MPPSSHQGLLVQQLSPQPPQGP 3798
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/164 (30%), Positives = 61/164 (37%), Gaps = 19/164 (11%)
Query: 5 NSLPPYAQGLASP-QGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQ 63
N L P L P Q P P P++ G GL I T + + + Q Q
Sbjct: 4151 NLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPT-----VGQLRAQLQGVL 4205
Query: 64 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFH 123
+ Q + QQQQQ Q Q+Q QQ Q + T QG G PQ
Sbjct: 4206 AKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQ--- 4262
Query: 124 SQTLTTAPLPGTTPLY-----PSPMTPMTPITPATPASESSGIV 162
L P P T PL P P P P PA P + S+G V
Sbjct: 4263 ---LGGFPGPQTGPLQELGAGPRPQGP--PRLPAPPGALSTGPV 4301
Score = 39.3 bits (90), Expect = 0.005
Identities = 19/46 (41%), Positives = 28/46 (60%)
Query: 38 LTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQ 83
+T Q + L + +QQ++ + + +QQQQQQQQQQQQQQ
Sbjct: 3567 VTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612
Score = 34.3 bits (77), Expect = 0.16
Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 7/72 (9%)
Query: 84 QQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPM 143
QQQQQQ QQQQA AA +++ + S + S P+L + +PL G + P P
Sbjct: 2811 QQQQQQLWQQQQATAATSMRFAMS---ARFPSTPGPEL--GRQALGSPLAGISTRLPGPG 2865
Query: 144 TPMTPITPATPA 155
P+ PA PA
Sbjct: 2866 EPVP--GPAGPA 2875
Score = 33.5 bits (75), Expect = 0.28
Identities = 38/169 (22%), Positives = 64/169 (37%), Gaps = 23/169 (13%)
Query: 4 NNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQ 63
+ SLP + G + G +P P G+ L + T + Q
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGT-------QDPGMSGLSQ 2674
Query: 64 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFH 123
+ ++Q+Q+Q+ ++ +QQ Q+ +Q+++ A AAA + +S QL
Sbjct: 2675 TELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSR 2734
Query: 124 SQ-----TLTTAPLPGTTP-----------LYPSPMTPMTPITPATPAS 156
Q T + L G P +PS P PATP+S
Sbjct: 2735 GQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSS 2783
Score = 28.5 bits (62), Expect = 9.0
Identities = 23/111 (20%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
Query: 55 QQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114
+QR ++ ++ + ++ + +QQ + Q+Q Q ++QQ + + ++Q Q
Sbjct: 3545 KQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQ 3604
Query: 115 SGQAPQLFHSQTLTTAP--LPGTTPLYPSPMTPMTPITP--ATPASESSGI 161
Q Q HS L +P P P + P + P P ++ G+
Sbjct: 3605 QQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGL 3655
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 76.6 bits (187), Expect = 3e-14
Identities = 64/186 (34%), Positives = 75/186 (40%), Gaps = 36/186 (19%)
Query: 7 LPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEE----------QQ 56
L P G P+GA+ PG P + G G QP Q L L++ Q
Sbjct: 399 LAPGEFGNHRPKGALRPGN---GPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQH 455
Query: 57 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----------------------QQQQQQQ 93
R QQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQ Q
Sbjct: 456 RHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQ 515
Query: 94 QQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPAT 153
QQ + + Q S Q Q F Q + P P +T +PA
Sbjct: 516 QQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSPQEFSPAL 575
Query: 154 PASESS 159
+ SS
Sbjct: 576 VSYTSS 581
Score = 32.3 bits (72), Expect = 0.62
Identities = 30/93 (32%), Positives = 38/93 (40%), Gaps = 14/93 (15%)
Query: 51 ILEEQQRQQQQQQQQQQQQQQQQ---------QQQQQQQQQQQQQQQQQQQQQQAVAAAA 101
+L++ QQ Q QQQQ QQQ Q Q Q QQ QQQ +A
Sbjct: 495 LLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLA--- 551
Query: 102 VQQSTSQQATQGTSGQAPQLFHSQTLT-TAPLP 133
Q SQQ +PQ F ++ T+ LP
Sbjct: 552 -QHQPSQQQASPEYLTSPQEFSPALVSYTSSLP 583
Score = 28.9 bits (63), Expect = 6.9
Identities = 19/57 (33%), Positives = 23/57 (40%)
Query: 58 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114
Q Q QQ QQQ Q Q QQQ + Q + A V ++S A GT
Sbjct: 532 QYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSPQEFSPALVSYTSSLPAQVGT 588
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 76.6 bits (187), Expect = 3e-14
Identities = 64/186 (34%), Positives = 75/186 (40%), Gaps = 36/186 (19%)
Query: 7 LPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEE----------QQ 56
L P G P+GA+ PG P + G G QP Q L L++ Q
Sbjct: 399 LAPGEFGNHRPKGALRPGN---GPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQH 455
Query: 57 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----------------------QQQQQQQ 93
R QQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQ Q
Sbjct: 456 RHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQ 515
Query: 94 QQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPAT 153
QQ + + Q S Q Q F Q + P P +T +PA
Sbjct: 516 QQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSPQEFSPAL 575
Query: 154 PASESS 159
+ SS
Sbjct: 576 VSYTSS 581
Score = 32.3 bits (72), Expect = 0.62
Identities = 30/93 (32%), Positives = 38/93 (40%), Gaps = 14/93 (15%)
Query: 51 ILEEQQRQQQQQQQQQQQQQQQQ---------QQQQQQQQQQQQQQQQQQQQQQAVAAAA 101
+L++ QQ Q QQQQ QQQ Q Q Q QQ QQQ +A
Sbjct: 495 LLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLA--- 551
Query: 102 VQQSTSQQATQGTSGQAPQLFHSQTLT-TAPLP 133
Q SQQ +PQ F ++ T+ LP
Sbjct: 552 -QHQPSQQQASPEYLTSPQEFSPALVSYTSSLP 583
Score = 28.9 bits (63), Expect = 6.9
Identities = 19/57 (33%), Positives = 23/57 (40%)
Query: 58 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114
Q Q QQ QQQ Q Q QQQ + Q + A V ++S A GT
Sbjct: 532 QYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSPQEFSPALVSYTSSLPAQVGT 588
>gi|40354197 THAP domain containing 11 [Homo sapiens]
Length = 314
Score = 76.6 bits (187), Expect = 3e-14
Identities = 41/82 (50%), Positives = 57/82 (69%), Gaps = 2/82 (2%)
Query: 64 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFH 123
+++QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ+ +A+ Q+ Q ++ A L
Sbjct: 101 RRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQPNLVSASAAVLLTL 160
Query: 124 SQTLTTAPLPGTTPLYPSPMTP 145
T+ ++ PG+ + P+P+TP
Sbjct: 161 QATVDSSQAPGS--VQPAPITP 180
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/87 (35%), Positives = 37/87 (42%), Gaps = 10/87 (11%)
Query: 33 PYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 92
P G + Q ++QQ+QQQQQQ QQQQQQQQ Q Q
Sbjct: 94 PAGAAAARRRQQQQQQQQQQQQQQQQQQQQQ--------QQQQQQQQSSPSASTAQTAQL 145
Query: 93 QQQAVAAAAVQQSTSQQATQGTSGQAP 119
Q V+A+A T Q S QAP
Sbjct: 146 QPNLVSASAAVLLTLQATVD--SSQAP 170
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 72.4 bits (176), Expect = 5e-13
Identities = 39/71 (54%), Positives = 43/71 (60%)
Query: 24 GIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQ 83
G + PMM G + S +L RQQ+ QQQQQQQQQQQQQQQQQQ
Sbjct: 1202 GAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQ 1261
Query: 84 QQQQQQQQQQQ 94
QQQQQQQQQQQ
Sbjct: 1262 QQQQQQQQQQQ 1272
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 72.4 bits (176), Expect = 5e-13
Identities = 59/164 (35%), Positives = 75/164 (45%), Gaps = 17/164 (10%)
Query: 7 LPPYAQGLASPQGAMTPGIPIF-----SPMMPYGTGLTPQPIQNTNSLSILEEQQRQQ-Q 60
+P Q ++ P +P P+ + ++ Y QP+ T L++ ++ Q
Sbjct: 157 IPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQ 216
Query: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
QQQQQQQQQQQQQQQQQQQQQQ QQQ Q Q QQ QQ + SG P+
Sbjct: 217 QQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQ--------QQQPALVNYNRPSGPGPE 268
Query: 121 LFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQ 164
L T P+P PSP P PA S VPQ
Sbjct: 269 LSGPSTPQKLPVPAPGG-RPSPAPPAAAQPPAAAVPGPS--VPQ 309
Score = 52.0 bits (123), Expect = 8e-07
Identities = 54/218 (24%), Positives = 87/218 (39%), Gaps = 36/218 (16%)
Query: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
++QQ+QQQQQQQQQ QQQ Q Q QQQQQ + ++ + Q A
Sbjct: 225 QQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPG 284
Query: 113 GTSGQAPQLFHSQTLTTAP---LPGTTPLYPSPMTPM-TPITPATPASESSGIVP----- 163
G AP P +P P PSP+ + + +P + G+ P
Sbjct: 285 GRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQ 344
Query: 164 ---------------QLQNIVSTV--NLGCKLDLKTIALRARNAEYNPKRFAAVIMRIRE 206
+L+N+ ++ +L K ++ ALR N + ++ MR
Sbjct: 345 EREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDT 404
Query: 207 PRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKL 244
TAL +K+ ++S+ + AR+ +KL
Sbjct: 405 TLETAL----------NSKAYKRSKRQTLREARMTEKL 432
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 72.4 bits (176), Expect = 5e-13
Identities = 59/164 (35%), Positives = 75/164 (45%), Gaps = 17/164 (10%)
Query: 7 LPPYAQGLASPQGAMTPGIPIF-----SPMMPYGTGLTPQPIQNTNSLSILEEQQRQQ-Q 60
+P Q ++ P +P P+ + ++ Y QP+ T L++ ++ Q
Sbjct: 157 IPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQ 216
Query: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
QQQQQQQQQQQQQQQQQQQQQQ QQQ Q Q QQ QQ + SG P+
Sbjct: 217 QQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQ--------QQQPALVNYNRPSGPGPE 268
Query: 121 LFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQ 164
L T P+P PSP P PA S VPQ
Sbjct: 269 LSGPSTPQKLPVPAPGG-RPSPAPPAAAQPPAAAVPGPS--VPQ 309
Score = 52.0 bits (123), Expect = 8e-07
Identities = 54/218 (24%), Positives = 87/218 (39%), Gaps = 36/218 (16%)
Query: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
++QQ+QQQQQQQQQ QQQ Q Q QQQQQ + ++ + Q A
Sbjct: 225 QQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPG 284
Query: 113 GTSGQAPQLFHSQTLTTAP---LPGTTPLYPSPMTPM-TPITPATPASESSGIVP----- 163
G AP P +P P PSP+ + + +P + G+ P
Sbjct: 285 GRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQ 344
Query: 164 ---------------QLQNIVSTV--NLGCKLDLKTIALRARNAEYNPKRFAAVIMRIRE 206
+L+N+ ++ +L K ++ ALR N + ++ MR
Sbjct: 345 EREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDT 404
Query: 207 PRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKL 244
TAL +K+ ++S+ + AR+ +KL
Sbjct: 405 TLETAL----------NSKAYKRSKRQTLREARMTEKL 432
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 71.6 bits (174), Expect = 9e-13
Identities = 54/129 (41%), Positives = 65/129 (50%), Gaps = 28/129 (21%)
Query: 58 QQQQQQQQQQQQQQ-------------QQQQQQ-------QQQQQQQQQQQQQQQQQQAV 97
QQQQQ QQQQQQQQ QQQQQQ Q QQQQQQQQQQQQQQQQA+
Sbjct: 205 QQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL 264
Query: 98 -AAAAVQQSTSQQ----ATQGTSGQAPQLFHSQTLTTAPLPGTTPL---YPSPMTPMTPI 149
A +QQ QQ +Q Q Q+ H+Q P P P+ PS + P +
Sbjct: 265 QAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQT 324
Query: 150 TPATPASES 158
P +++
Sbjct: 325 QPLVSQAQA 333
Score = 66.6 bits (161), Expect = 3e-11
Identities = 58/164 (35%), Positives = 68/164 (41%), Gaps = 25/164 (15%)
Query: 16 SPQGAMTPGIPIFSP-MMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQ 74
S G PG +P M + TPQ +++ ++QQ+QQ QQQQQ QQQQQQ
Sbjct: 124 SLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQ 183
Query: 75 QQQQQ----------------QQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ------ 112
QQQQQ QQQQQ QQQQQQQQ QQ QQ Q
Sbjct: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ 243
Query: 113 -GTSGQAPQLFHSQTLTTAPLPGTTPLYPSPM-TPMTPITPATP 154
Q Q Q L P+ PM P P + A P
Sbjct: 244 LQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287
Score = 65.5 bits (158), Expect = 7e-11
Identities = 46/120 (38%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Query: 8 PPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQ 67
P + G GAM + + P +G+ P + ++ + + Q QQ QQQQQ
Sbjct: 106 PGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ 165
Query: 68 QQQQQQQQQQQQQQQQQQQQQQQQQQQQAVA----AAAVQQSTSQQATQGTSGQAPQLFH 123
QQQ QQQQQ QQQQQQQQQQQ Q QQ+ A VQQ Q Q +L H
Sbjct: 166 QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHH 225
Score = 28.5 bits (62), Expect = 9.0
Identities = 39/168 (23%), Positives = 59/168 (35%), Gaps = 12/168 (7%)
Query: 8 PPYAQGLAS--PQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEE---QQRQQQQQ 62
PP AQ S P + T + + +P T P++ + ++++ Q + QQQQ
Sbjct: 308 PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367
Query: 63 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLF 122
Q Q Q Q + Q + + AV S G A
Sbjct: 368 TAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQ 427
Query: 123 HSQTLTTAPLPGTTPLYPS--PMTPMTPITPATPASE-----SSGIVP 163
S + ++P PG P P P P P+S+ SSG P
Sbjct: 428 SSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAP 475
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 71.6 bits (174), Expect = 9e-13
Identities = 54/129 (41%), Positives = 65/129 (50%), Gaps = 28/129 (21%)
Query: 58 QQQQQQQQQQQQQQ-------------QQQQQQ-------QQQQQQQQQQQQQQQQQQAV 97
QQQQQ QQQQQQQQ QQQQQQ Q QQQQQQQQQQQQQQQQA+
Sbjct: 205 QQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL 264
Query: 98 -AAAAVQQSTSQQ----ATQGTSGQAPQLFHSQTLTTAPLPGTTPL---YPSPMTPMTPI 149
A +QQ QQ +Q Q Q+ H+Q P P P+ PS + P +
Sbjct: 265 QAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQT 324
Query: 150 TPATPASES 158
P +++
Sbjct: 325 QPLVSQAQA 333
Score = 66.6 bits (161), Expect = 3e-11
Identities = 58/164 (35%), Positives = 68/164 (41%), Gaps = 25/164 (15%)
Query: 16 SPQGAMTPGIPIFSP-MMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQ 74
S G PG +P M + TPQ +++ ++QQ+QQ QQQQQ QQQQQQ
Sbjct: 124 SLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQ 183
Query: 75 QQQQQ----------------QQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ------ 112
QQQQQ QQQQQ QQQQQQQQ QQ QQ Q
Sbjct: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ 243
Query: 113 -GTSGQAPQLFHSQTLTTAPLPGTTPLYPSPM-TPMTPITPATP 154
Q Q Q L P+ PM P P + A P
Sbjct: 244 LQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287
Score = 65.5 bits (158), Expect = 7e-11
Identities = 46/120 (38%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Query: 8 PPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQ 67
P + G GAM + + P +G+ P + ++ + + Q QQ QQQQQ
Sbjct: 106 PGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ 165
Query: 68 QQQQQQQQQQQQQQQQQQQQQQQQQQQQAVA----AAAVQQSTSQQATQGTSGQAPQLFH 123
QQQ QQQQQ QQQQQQQQQQQ Q QQ+ A VQQ Q Q +L H
Sbjct: 166 QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHH 225
Score = 35.4 bits (80), Expect = 0.073
Identities = 34/155 (21%), Positives = 53/155 (34%), Gaps = 4/155 (2%)
Query: 8 PPYAQGLAS--PQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQ 65
PP AQ S P + T + + +P T P++ + ++++ Q Q QQQQ
Sbjct: 308 PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367
Query: 66 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQ 125
Q Q Q Q Q QS P +
Sbjct: 368 TAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNS 427
Query: 126 TLTTAPLPGTTPLYPSP--MTPMTPITPATPASES 158
+++ P P + PSP +P+T TP + S
Sbjct: 428 NVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFS 462
Score = 33.9 bits (76), Expect = 0.21
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)
Query: 72 QQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAP 131
QQ Q Q QQQQ Q Q Q V QS+ + + GQ Q+ Q++ P
Sbjct: 355 QQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQ--QVQTPQSMPPPP 412
Query: 132 LPGTTPLYPSPMTPMTPITPATPASESSGIVP 163
P P PS P + ++ + PA S +P
Sbjct: 413 QPSPQPGQPSSQ-PNSNVS-SGPAPSPSSFLP 442
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 70.1 bits (170), Expect = 3e-12
Identities = 37/69 (53%), Positives = 42/69 (60%)
Query: 26 PIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 85
P+ P + G + S +L RQQ+ QQQQQQQQQQQQQQQQQQQQ
Sbjct: 1208 PMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQ 1267
Query: 86 QQQQQQQQQ 94
QQQQQQQQQ
Sbjct: 1268 QQQQQQQQQ 1276
Score = 57.4 bits (137), Expect = 2e-08
Identities = 45/127 (35%), Positives = 57/127 (44%), Gaps = 17/127 (13%)
Query: 24 GIPIFSPMMPYGTGLTPQPIQNTNSLS--ILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQ 81
G + PMM PQ L+ ++ ++ R+ +QQ+ QQQQQQQQ
Sbjct: 1202 GAAVMRPMMQ------PQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQ 1255
Query: 82 QQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPS 141
QQQQQQQQQQQQQ QQ QQ TQ S P + S ++ T P P
Sbjct: 1256 QQQQQQQQQQQQQ--------QQQQQQQQTQAFS-PPPNVTASPSMDGLLAGPTMPQAPP 1306
Query: 142 PMTPMTP 148
P P
Sbjct: 1307 QQFPYQP 1313
>gi|189491748 ataxin 1 [Homo sapiens]
Length = 815
Score = 69.7 bits (169), Expect = 4e-12
Identities = 62/174 (35%), Positives = 76/174 (43%), Gaps = 24/174 (13%)
Query: 9 PYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQ 68
P +AS GA TP S + Y T L N SLS + +QQQQQQQQQQ
Sbjct: 154 PVTSAVASAAGATTPSQR--SQLEAYSTLLA-----NMGSLSQTPGHKAEQQQQQQQQQQ 206
Query: 69 QQQQQQQQQQQQQQQQQQQQQQQ-------------QQQQAVAAAAVQQSTSQQATQGTS 115
QQ Q QQQQQQQQQQQQQQ + QQ Q V ++ Q+T + A+
Sbjct: 207 QQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAI 266
Query: 116 G---QAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQ 166
Q TLT P Y + P AT +ESS + +Q
Sbjct: 267 PVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVP-REATKKAESSRLQQAIQ 319
>gi|51479158 ataxin 1 [Homo sapiens]
Length = 815
Score = 69.7 bits (169), Expect = 4e-12
Identities = 62/174 (35%), Positives = 76/174 (43%), Gaps = 24/174 (13%)
Query: 9 PYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQ 68
P +AS GA TP S + Y T L N SLS + +QQQQQQQQQQ
Sbjct: 154 PVTSAVASAAGATTPSQR--SQLEAYSTLLA-----NMGSLSQTPGHKAEQQQQQQQQQQ 206
Query: 69 QQQQQQQQQQQQQQQQQQQQQQQ-------------QQQQAVAAAAVQQSTSQQATQGTS 115
QQ Q QQQQQQQQQQQQQQ + QQ Q V ++ Q+T + A+
Sbjct: 207 QQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAI 266
Query: 116 G---QAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQ 166
Q TLT P Y + P AT +ESS + +Q
Sbjct: 267 PVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVP-REATKKAESSRLQQAIQ 319
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 69.7 bits (169), Expect = 4e-12
Identities = 54/157 (34%), Positives = 69/157 (43%), Gaps = 26/157 (16%)
Query: 16 SPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQ 75
+P ++ P + + + G +TP Q +L +QQ+QQQQQQQQQQQQQQQQQQ
Sbjct: 2687 TPARSLVPQVSQATGVQLPGKTITPAHFQ------LLRQQQQQQQQQQQQQQQQQQQQQQ 2740
Query: 76 QQQQQQQ-----QQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTA 130
QQQQQQQ Q Q Q Q Q Q AV + T + + Q L
Sbjct: 2741 QQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIK---------MQKQKLQMP 2791
Query: 131 PLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQN 167
P P P P P P + PQ Q+
Sbjct: 2792 PQP------PPPQAQSAPPQPTAQVQVQTSQPPQQQS 2822
Score = 44.3 bits (103), Expect = 2e-04
Identities = 57/177 (32%), Positives = 70/177 (39%), Gaps = 18/177 (10%)
Query: 8 PPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQ 67
P AQG A+ Q +T I +P QP T L+ Q ++ QQ Q
Sbjct: 2945 PQAAQGPAAVQQKITAQ-QITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQT 3003
Query: 68 QQQQQQQQQQQQQQQ-----QQQQQQQQQQQQQAVA----AAAVQQSTSQQATQGTSGQA 118
Q Q + Q QQQ QQ QQ Q VA AA QQ A T+
Sbjct: 3004 QIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVV 3063
Query: 119 PQ-LFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNL 174
Q L Q +TTA P TP P+P PA +S+S P+LQ V V L
Sbjct: 3064 QQKLIQQQVVTTASAPLQTPGAPNPAQ-----VPA--SSDSPSQQPKLQMRVPAVRL 3113
Score = 36.6 bits (83), Expect = 0.033
Identities = 41/147 (27%), Positives = 56/147 (38%), Gaps = 13/147 (8%)
Query: 36 TGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----- 90
T +T + TN L+ ++ R Q Q Q + Q +QQQQQ
Sbjct: 2670 TSVTASAVVTTN-LTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQ 2728
Query: 91 QQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPM---- 146
QQQQQ QQ QQ T + Q PQ+ Q + A + L P + M
Sbjct: 2729 QQQQQQQQQQQQQQQQQQQTTTTSQVQVPQI-QGQAQSPAQIKAVGKLTPEHLIKMQKQK 2787
Query: 147 --TPITPATPASESSGIVPQLQNIVST 171
P P P ++S+ P Q V T
Sbjct: 2788 LQMPPQPPPPQAQSAPPQPTAQVQVQT 2814
Score = 36.2 bits (82), Expect = 0.043
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 8/129 (6%)
Query: 3 QNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQ 62
Q + P LA P P + SP G+T P+ + + Q+ Q
Sbjct: 2865 QTQAPQPAQVALAKPPVVSVPAAVVSSP------GVTTLPMNVAGISVAIGQPQKAAGQT 2918
Query: 63 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAV--QQSTSQQATQGTSGQAPQ 120
Q QQ + +QQ QQQ+ Q Q Q A + QQ T+ A Q + A
Sbjct: 2919 VVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQP 2978
Query: 121 LFHSQTLTT 129
+Q LTT
Sbjct: 2979 ALKTQFLTT 2987
Score = 36.2 bits (82), Expect = 0.043
Identities = 34/143 (23%), Positives = 51/143 (35%), Gaps = 7/143 (4%)
Query: 17 PQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQ 76
P + I P G + QP+ +++ + +QQ QQQ+ Q Q Q
Sbjct: 2898 PMNVAGISVAIGQPQKAAGQTVVAQPVH-------MQQLLKLKQQAVQQQKAIQPQAAQG 2950
Query: 77 QQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTT 136
QQ+ QQ Q A A Q + Q QA +L +Q + T
Sbjct: 2951 PAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKL 3010
Query: 137 PLYPSPMTPMTPITPATPASESS 159
P TP+ I AS+ +
Sbjct: 3011 PQVVQQQTPVASIQQVASASQQA 3033
Score = 34.7 bits (78), Expect = 0.13
Identities = 36/146 (24%), Positives = 48/146 (32%), Gaps = 19/146 (13%)
Query: 12 QGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQ 71
QG+ G+P+ M G+ P P Q Q Q+Q QQQ
Sbjct: 490 QGVVFQHPGADAGVPLQQLMPTAQGGMPPTP---------------QAAQLAGQRQSQQQ 534
Query: 72 QQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAP 131
Q Q + A V + A Q Q PQ+ +QT P
Sbjct: 535 YDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQ--FAQQPQVVEAQTQLQIP 592
Query: 132 LPGTTPLYPSPMTPMT--PITPATPA 155
+ P P P P + PI P+ PA
Sbjct: 593 VKTQQPNVPIPAPPSSQLPIPPSQPA 618
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 69.3 bits (168), Expect = 5e-12
Identities = 51/148 (34%), Positives = 63/148 (42%), Gaps = 20/148 (13%)
Query: 12 QGLASPQGAMTPGIP--------IFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQ 63
Q +P A TPG + +P G P+ +S EQ +Q QQ
Sbjct: 416 QSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQ 475
Query: 64 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFH 123
QQ+ + QQ+QQQQQQQQQQQQQQQQQQQQQ + T S P
Sbjct: 476 QQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHS------------NQTSNWSPLGPPSSP 523
Query: 124 SQTLTTAPLPGTTPLYPSPMTPMTPITP 151
TA P + +YP PI P
Sbjct: 524 YGAAFTAEKPNSPMMYPQAFNNQNPIVP 551
Score = 49.7 bits (117), Expect = 4e-06
Identities = 50/161 (31%), Positives = 67/161 (41%), Gaps = 12/161 (7%)
Query: 5 NSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQ 64
+S+PP + G+ S PG F P + I L EQQ+QQ ++Q
Sbjct: 705 SSVPPGSGGMVSGASPAGPG---FLGSQPQAAIMKQMLIDQRAQLI---EQQKQQFLREQ 758
Query: 65 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQ-STSQQATQGTSGQAPQLFH 123
+QQQQQQQQ +QQ QQ +Q Q Q+ V Q S Q QA
Sbjct: 759 RQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSM 818
Query: 124 SQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESS-GIVP 163
+ A G + PS P T AT A++S G+ P
Sbjct: 819 RTSRLMAQNAGMMGIGPS----QNPGTMATAAAQSEMGLAP 855
Score = 48.1 bits (113), Expect = 1e-05
Identities = 39/126 (30%), Positives = 56/126 (44%), Gaps = 23/126 (18%)
Query: 38 LTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----- 92
+TP P+ N N ++ Q+QQQQQQQQQQQQQQQQ Q Q + + Q++
Sbjct: 612 MTP-PVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMK 670
Query: 93 ----QQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTP 148
Q +A AA+ +Q G TT P+ + P P ++
Sbjct: 671 QKGVMNQPMAYAALPSHGQEQHPVGL-----------PRTTGPMQSSVP--PGSGGMVSG 717
Query: 149 ITPATP 154
+PA P
Sbjct: 718 ASPAGP 723
Score = 43.9 bits (102), Expect = 2e-04
Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 5/112 (4%)
Query: 6 SLPPYAQ-----GLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQ 60
+LP + Q GL G M +P S M G + + + +Q Q
Sbjct: 683 ALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQ 742
Query: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
+ Q +QQ+QQ ++Q+QQQQQQQQ +QQ QQ + +Q + Q
Sbjct: 743 RAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQ 794
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 67.4 bits (163), Expect = 2e-11
Identities = 62/170 (36%), Positives = 77/170 (45%), Gaps = 25/170 (14%)
Query: 24 GIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQ---- 79
G P+ S M G P +T ++ QQ Q Q QQQQQQQQQQ QQ QQQQ
Sbjct: 407 GAPLISSMGTTMVGSAP----STQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQH 462
Query: 80 ------QQQQQQQ------QQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTL 127
QQQ QQQ QQ QQQQQ + QQ QQ Q Q QL H Q
Sbjct: 463 QMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRL--QLQQLQHMQHQ 520
Query: 128 TTAPLPGTTPLYPSPMTPMTPITPATPASE--SSGIVPQLQ-NIVSTVNL 174
+ +P+ +P+ I PAS+ S I Q Q ++S V++
Sbjct: 521 SQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVLSQVSI 570
Score = 54.3 bits (129), Expect = 2e-07
Identities = 40/120 (33%), Positives = 47/120 (39%), Gaps = 1/120 (0%)
Query: 6 SLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQ 65
S+ P + P + + I + MP G T + Q Q QQ
Sbjct: 377 SIAPKPLTMRLPMNQIVTSVTI-AANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQ 435
Query: 66 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQ 125
Q Q QQQQQQQQQQ QQ QQQQ QQ Q +QQ Q Q Q Q Q
Sbjct: 436 HQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQ 495
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 67.4 bits (163), Expect = 2e-11
Identities = 62/170 (36%), Positives = 77/170 (45%), Gaps = 25/170 (14%)
Query: 24 GIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQ---- 79
G P+ S M G P +T ++ QQ Q Q QQQQQQQQQQ QQ QQQQ
Sbjct: 412 GAPLISSMGTTMVGSAP----STQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQH 467
Query: 80 ------QQQQQQQ------QQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTL 127
QQQ QQQ QQ QQQQQ + QQ QQ Q Q QL H Q
Sbjct: 468 QMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRL--QLQQLQHMQHQ 525
Query: 128 TTAPLPGTTPLYPSPMTPMTPITPATPASE--SSGIVPQLQ-NIVSTVNL 174
+ +P+ +P+ I PAS+ S I Q Q ++S V++
Sbjct: 526 SQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVLSQVSI 575
Score = 54.3 bits (129), Expect = 2e-07
Identities = 40/120 (33%), Positives = 47/120 (39%), Gaps = 1/120 (0%)
Query: 6 SLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQ 65
S+ P + P + + I + MP G T + Q Q QQ
Sbjct: 382 SIAPKPLTMRLPMNQIVTSVTI-AANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQ 440
Query: 66 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQ 125
Q Q QQQQQQQQQQ QQ QQQQ QQ Q +QQ Q Q Q Q Q
Sbjct: 441 HQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQ 500
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 67.4 bits (163), Expect = 2e-11
Identities = 43/87 (49%), Positives = 53/87 (60%), Gaps = 7/87 (8%)
Query: 23 PGIP-IFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQ 81
PG+P F+P +P P P+Q+ + Q QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 492 PGLPGEFTPPVPDSFPSGP-PLQHP-----APDHQSLQQQQQQQQQQQQQQQQQQQQQQQ 545
Query: 82 QQQQQQQQQQQQQQAVAAAAVQQSTSQ 108
QQQQQ+Q + +A+ QQ Q
Sbjct: 546 QQQQQRQNAALMIKQMASRNQQQRLRQ 572
Score = 67.4 bits (163), Expect = 2e-11
Identities = 37/68 (54%), Positives = 41/68 (60%)
Query: 56 QRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTS 115
Q Q QQQQQQQQQQQQQQQQQQQQQQQQQQQQ+Q A Q ++ Q +
Sbjct: 513 QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572
Query: 116 GQAPQLFH 123
QL H
Sbjct: 573 PNLAQLGH 580
Score = 66.6 bits (161), Expect = 3e-11
Identities = 35/55 (63%), Positives = 37/55 (67%)
Query: 55 QQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQ 109
Q Q QQQQQQQQQQQQQQQQQQQQQQQQQQQQ+Q A S +QQ
Sbjct: 513 QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQ 567
Score = 50.4 bits (119), Expect = 2e-06
Identities = 30/70 (42%), Positives = 33/70 (47%)
Query: 65 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHS 124
Q Q QQQQQQQQQQQQQQQQQQQQQ +Q+ + Q S Q
Sbjct: 513 QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572
Query: 125 QTLTTAPLPG 134
L PG
Sbjct: 573 PNLAQLGHPG 582
Score = 45.4 bits (106), Expect = 7e-05
Identities = 47/150 (31%), Positives = 54/150 (36%), Gaps = 48/150 (32%)
Query: 2 DQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQ 61
D LP YA G P GA PG + MP G+ LS + Q QQQ
Sbjct: 251 DSEGQLPHYAAGRQVPGGAF-PG----ASAMPRAAGMV--------GLSKMHAQPPQQQP 297
Query: 62 QQQQQQQQQQQQQ-------------------------------QQQQQQQQQQQQQQQQ 90
QQQQQ QQQQQQ QQ QQQ QQ
Sbjct: 298 QQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPP 357
Query: 91 QQQQQAVAAAAVQQSTSQQA----TQGTSG 116
QQQ V+Q++ A QG +G
Sbjct: 358 QQQPPPPPGLLVRQNSCPPALPRPQQGEAG 387
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 67.0 bits (162), Expect = 2e-11
Identities = 49/141 (34%), Positives = 62/141 (43%), Gaps = 8/141 (5%)
Query: 50 SILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQ 109
S+L QQ+QQQQQQQQQQQQQQQQQQQQ+ +QQQQQQ + QA +
Sbjct: 53 SLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDE 112
Query: 110 ATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIV 169
Q + Q+ H + P PG + P P E P +++
Sbjct: 113 EQQPSQPQSALECHPER-GCVPEPGAAVAASKGLPQQLP----APPDEDDSAAPSTLSLL 167
Query: 170 STVNLG---CKLDLKTIALRA 187
G C DLK I A
Sbjct: 168 GPTFPGLSSCSADLKDILSEA 188
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 10/85 (11%)
Query: 23 PGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQ 82
P P + P G L Q ++QQ+QQQQQQQ+ +QQQQQQ + Q
Sbjct: 39 PRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQ 98
Query: 83 QQQ----------QQQQQQQQQQAV 97
+ ++QQ Q Q A+
Sbjct: 99 AHRRGPTGYLVLDEEQQPSQPQSAL 123
>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1662
Score = 64.3 bits (155), Expect = 1e-10
Identities = 33/56 (58%), Positives = 37/56 (66%)
Query: 59 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114
++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A AA A + T T
Sbjct: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSAT 1648
Score = 62.8 bits (151), Expect = 4e-10
Identities = 31/44 (70%), Positives = 34/44 (77%)
Query: 57 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAA 100
R ++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ AAA
Sbjct: 1590 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAA 1633
Score = 62.8 bits (151), Expect = 4e-10
Identities = 31/46 (67%), Positives = 35/46 (76%)
Query: 58 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103
++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A A AA +
Sbjct: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATE 1638
Score = 60.5 bits (145), Expect = 2e-09
Identities = 34/65 (52%), Positives = 38/65 (58%)
Query: 47 NSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQST 106
N +L + + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A AA +
Sbjct: 1584 NYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGS 1643
Query: 107 SQQAT 111
AT
Sbjct: 1644 PTSAT 1648
Score = 59.7 bits (143), Expect = 4e-09
Identities = 32/61 (52%), Positives = 36/61 (59%)
Query: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQL 121
++ + QQQQQQQQQQQQQQQQQQQQQQQQQ AAA +T TS
Sbjct: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST 1652
Query: 122 F 122
F
Sbjct: 1653 F 1653
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 8/77 (10%)
Query: 44 QNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103
Q L+ +EE R + ++ + QQQQQQQQQQQQQQQQQQQ Q
Sbjct: 1570 QRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQ--------Q 1621
Query: 104 QSTSQQATQGTSGQAPQ 120
Q QQ +G A +
Sbjct: 1622 QQQQQQQVAAAAGAATE 1638
Score = 30.0 bits (66), Expect = 3.1
Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 10/100 (10%)
Query: 51 ILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQA 110
+ E QRQ+ + ++ + + ++ + QQQQQQQQ QQ QQ
Sbjct: 1565 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQ------QQQQQQQQ 1618
Query: 111 TQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPIT 150
Q Q Q+ + T PG+ P+ T M+ T
Sbjct: 1619 QQQQQQQQQQVAAAAGAATEHPPGS----PTSATVMSTFT 1654
>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 64.3 bits (155), Expect = 1e-10
Identities = 33/56 (58%), Positives = 37/56 (66%)
Query: 59 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114
++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A AA A + T T
Sbjct: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSAT 1796
Score = 62.8 bits (151), Expect = 4e-10
Identities = 31/44 (70%), Positives = 34/44 (77%)
Query: 57 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAA 100
R ++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ AAA
Sbjct: 1738 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAA 1781
Score = 62.8 bits (151), Expect = 4e-10
Identities = 31/46 (67%), Positives = 35/46 (76%)
Query: 58 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103
++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A A AA +
Sbjct: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATE 1786
Score = 60.5 bits (145), Expect = 2e-09
Identities = 34/65 (52%), Positives = 38/65 (58%)
Query: 47 NSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQST 106
N +L + + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A AA +
Sbjct: 1732 NYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGS 1791
Query: 107 SQQAT 111
AT
Sbjct: 1792 PTSAT 1796
Score = 59.7 bits (143), Expect = 4e-09
Identities = 32/61 (52%), Positives = 36/61 (59%)
Query: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQL 121
++ + QQQQQQQQQQQQQQQQQQQQQQQQQ AAA +T TS
Sbjct: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST 1800
Query: 122 F 122
F
Sbjct: 1801 F 1801
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 8/77 (10%)
Query: 44 QNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103
Q L+ +EE R + ++ + QQQQQQQQQQQQQQQQQQQ Q
Sbjct: 1718 QRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQ--------Q 1769
Query: 104 QSTSQQATQGTSGQAPQ 120
Q QQ +G A +
Sbjct: 1770 QQQQQQQVAAAAGAATE 1786
Score = 30.0 bits (66), Expect = 3.1
Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 10/100 (10%)
Query: 51 ILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQA 110
+ E QRQ+ + ++ + + ++ + QQQQQQQQ QQ QQ
Sbjct: 1713 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQ------QQQQQQQQ 1766
Query: 111 TQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPIT 150
Q Q Q+ + T PG+ P+ T M+ T
Sbjct: 1767 QQQQQQQQQQVAAAAGAATEHPPGS----PTSATVMSTFT 1802
>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 64.3 bits (155), Expect = 1e-10
Identities = 33/56 (58%), Positives = 37/56 (66%)
Query: 59 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114
++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A AA A + T T
Sbjct: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSAT 1796
Score = 62.8 bits (151), Expect = 4e-10
Identities = 31/44 (70%), Positives = 34/44 (77%)
Query: 57 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAA 100
R ++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ AAA
Sbjct: 1738 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAA 1781
Score = 62.8 bits (151), Expect = 4e-10
Identities = 31/46 (67%), Positives = 35/46 (76%)
Query: 58 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103
++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A A AA +
Sbjct: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATE 1786
Score = 60.5 bits (145), Expect = 2e-09
Identities = 34/65 (52%), Positives = 38/65 (58%)
Query: 47 NSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQST 106
N +L + + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A AA +
Sbjct: 1732 NYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGS 1791
Query: 107 SQQAT 111
AT
Sbjct: 1792 PTSAT 1796
Score = 59.7 bits (143), Expect = 4e-09
Identities = 32/61 (52%), Positives = 36/61 (59%)
Query: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQL 121
++ + QQQQQQQQQQQQQQQQQQQQQQQQQ AAA +T TS
Sbjct: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST 1800
Query: 122 F 122
F
Sbjct: 1801 F 1801
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 8/77 (10%)
Query: 44 QNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103
Q L+ +EE R + ++ + QQQQQQQQQQQQQQQQQQQ Q
Sbjct: 1718 QRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQ--------Q 1769
Query: 104 QSTSQQATQGTSGQAPQ 120
Q QQ +G A +
Sbjct: 1770 QQQQQQQVAAAAGAATE 1786
Score = 30.0 bits (66), Expect = 3.1
Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 10/100 (10%)
Query: 51 ILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQA 110
+ E QRQ+ + ++ + + ++ + QQQQQQQQ QQ QQ
Sbjct: 1713 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQ------QQQQQQQQ 1766
Query: 111 TQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPIT 150
Q Q Q+ + T PG+ P+ T M+ T
Sbjct: 1767 QQQQQQQQQQVAAAAGAATEHPPGS----PTSATVMSTFT 1802
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.129 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,780,288
Number of Sequences: 37866
Number of extensions: 648869
Number of successful extensions: 50857
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 824
Number of HSP's successfully gapped in prelim test: 300
Number of HSP's that attempted gapping in prelim test: 11884
Number of HSP's gapped (non-prelim): 12973
length of query: 339
length of database: 18,247,518
effective HSP length: 103
effective length of query: 236
effective length of database: 14,347,320
effective search space: 3385967520
effective search space used: 3385967520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.