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Search of human proteins with 4507147
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo
sapiens]
(522 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo sapiens] 1081 0.0
gi|49533617 sterol O-acyltransferase 1 [Homo sapiens] 504 e-142
gi|145864459 diacylglycerol O-acyltransferase 1 [Homo sapiens] 134 2e-31
gi|154813191 IQ motif containing E isoform 1 [Homo sapiens] 34 0.28
gi|154813193 IQ motif containing E isoform 2 [Homo sapiens] 34 0.28
gi|45439333 porcupine isoform C [Homo sapiens] 34 0.37
gi|18426913 drebrin 1 isoform b [Homo sapiens] 33 0.63
gi|18426915 drebrin 1 isoform a [Homo sapiens] 33 0.63
gi|239754630 PREDICTED: hypothetical protein [Homo sapiens] 33 0.83
gi|239749175 PREDICTED: hypothetical protein XP_002346935 [Homo ... 33 0.83
gi|239743250 PREDICTED: hypothetical protein XP_002342811 [Homo ... 33 0.83
gi|239508925 PREDICTED: hypothetical protein [Homo sapiens] 33 0.83
gi|31377722 PERP, TP53 apoptosis effector [Homo sapiens] 32 1.1
gi|191252785 centrobin, centrosomal BRCA2 interacting protein is... 32 1.4
gi|80861396 centrobin, centrosomal BRCA2 interacting protein iso... 32 1.4
gi|57242782 MAX interactor 1 isoform a [Homo sapiens] 32 1.8
gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 31 3.1
gi|45439337 porcupine isoform E [Homo sapiens] 31 3.1
gi|45439329 porcupine isoform A [Homo sapiens] 31 3.1
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 30 4.1
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 30 4.1
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 30 4.1
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 30 4.1
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 30 4.1
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ... 30 4.1
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens] 30 4.1
gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens] 30 4.1
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 30 5.4
gi|10834994 interleukin 11 precursor [Homo sapiens] 30 5.4
gi|219689113 two pore segment channel 1 isoform 1 [Homo sapiens] 30 5.4
>gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo sapiens]
Length = 522
Score = 1081 bits (2795), Expect = 0.0
Identities = 522/522 (100%), Positives = 522/522 (100%)
Query: 1 MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQL 60
MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQL
Sbjct: 1 MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQL 60
Query: 61 RELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHF 120
RELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHF
Sbjct: 61 RELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHF 120
Query: 121 RTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLA 180
RTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLA
Sbjct: 121 RTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLA 180
Query: 181 PYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFL 240
PYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFL
Sbjct: 181 PYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFL 240
Query: 241 MKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKN 300
MKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKN
Sbjct: 241 MKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKN 300
Query: 301 FAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLH 360
FAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLH
Sbjct: 301 FAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLH 360
Query: 361 CWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARG 420
CWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARG
Sbjct: 361 CWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARG 420
Query: 421 VAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTM 480
VAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTM
Sbjct: 421 VAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTM 480
Query: 481 LFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT 522
LFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT
Sbjct: 481 LFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT 522
>gi|49533617 sterol O-acyltransferase 1 [Homo sapiens]
Length = 550
Score = 504 bits (1297), Expect = e-142
Identities = 239/427 (55%), Positives = 296/427 (69%), Gaps = 8/427 (1%)
Query: 102 KVFIIRKSLLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFG 161
K+FI R+SLLDEL+EV H RTIYHMFIA L +FI+STL +D+IDEGRL+LEF LL ++FG
Sbjct: 120 KIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFG 179
Query: 162 QLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGL------GCALLAAHAVVLCALP 215
+ P + TW MFLST PY + WA G + L G + VL P
Sbjct: 180 KFPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGP 239
Query: 216 VHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEG--IQAPSFSSYLY 273
+V + + LPPASR +++FEQ+RF+MK++SF+RE VP L + + + + P+ + YLY
Sbjct: 240 TYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLY 299
Query: 274 FLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFST 333
FLF PTLIYR++YPR P VRW YVA FAQ GC Y +I RLC P+F N+ +EPFS
Sbjct: 300 FLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSA 359
Query: 334 RALVLSILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRT 393
R LVL + ++ LPG+ +L L FFAFLHCWLNAFAEMLRFGDRMFY+DWWNSTS+SNYYRT
Sbjct: 360 RVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRT 419
Query: 394 WNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILF 453
WNVVVHDWLY Y Y+D L R + AML VF VSAV HEY L FFYPV+ +LF
Sbjct: 420 WNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLF 479
Query: 454 LVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLV 513
+ G NF+++D R P WNVLMWT LFLG G+ + Y QEWYAR+HCPL TF V
Sbjct: 480 MFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYV 539
Query: 514 TPRSWSC 520
PRSW+C
Sbjct: 540 RPRSWTC 546
>gi|145864459 diacylglycerol O-acyltransferase 1 [Homo sapiens]
Length = 488
Score = 134 bits (337), Expect = 2e-31
Identities = 96/342 (28%), Positives = 151/342 (44%), Gaps = 32/342 (9%)
Query: 179 LAPYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVR 238
+A +Q + A G T+ GL +A A +LC V + + P + +
Sbjct: 145 VAAFQVEKRLAVGALTEQAGL-LLHVANLATILCFPAAVVLLVESITPVGSLLALMAHTI 203
Query: 239 FLMKSYSFL-------REAVPGTLRARRGEGIQAPSFSSY---------LYFLFCPTLIY 282
+K +S+ R ++ AP SY YFLF PTL Y
Sbjct: 204 LFLKLFSYRDVNSWCRRARAKAASAGKKASSAAAPHTVSYPDNLTYRDLYYFLFAPTLCY 263
Query: 283 RETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTR---ALVLS 339
+PR+P +R ++ + + L ++ + VP N S +PF ++
Sbjct: 264 ELNFPRSPRIRKRFLLRRILEMLFFTQLQVGLIQQWMVPTIQN-SMKPFKDMDYSRIIER 322
Query: 340 ILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVH 399
+L +P + L+ F+ H LNA AE+++FGDR FYRDWWNS S + +++ WN+ VH
Sbjct: 323 LLKLAVPNHLIWLIFFYWLFHSCLNAVAELMQFGDREFYRDWWNSESVTYFWQNWNIPVH 382
Query: 400 DWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGM 459
W + Y+ LR ++ +A GVFL SA HEY+ L F L+ G M
Sbjct: 383 KWCIRHFYKPMLR--RGSSKWMARTGVFLASAFFHEYLVSVPLRMFR-----LWAFTGMM 435
Query: 460 ----LNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWY 497
L + + G N +W L +GQ I V +Y ++Y
Sbjct: 436 AQIPLAWFVGRFFQGNYGNAAVWLSLIIGQPIAVLMYVHDYY 477
>gi|154813191 IQ motif containing E isoform 1 [Homo sapiens]
Length = 695
Score = 34.3 bits (77), Expect = 0.28
Identities = 30/120 (25%), Positives = 46/120 (38%), Gaps = 15/120 (12%)
Query: 17 GGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQA----QGQLRELLDRAMREAI 72
G R R PC DG + QW + K +L++A Q R L R A
Sbjct: 506 GLPRPRSPCSDGRRDAAARVLQAQWKVYKHKKKKAVLDEAAVVLQAAFRGHLTRTKLLAS 565
Query: 73 QSY----------PSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRT 122
+++ P Q P+P P T P + ++ + II+ +L L +H T
Sbjct: 566 KAHGSEPPSVPGLPDQSSPVPRVPSPIAQATGSP-VQEEAIVIIQSALRAHLARARHSAT 624
>gi|154813193 IQ motif containing E isoform 2 [Homo sapiens]
Length = 679
Score = 34.3 bits (77), Expect = 0.28
Identities = 30/120 (25%), Positives = 46/120 (38%), Gaps = 15/120 (12%)
Query: 17 GGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQA----QGQLRELLDRAMREAI 72
G R R PC DG + QW + K +L++A Q R L R A
Sbjct: 490 GLPRPRSPCSDGRRDAAARVLQAQWKVYKHKKKKAVLDEAAVVLQAAFRGHLTRTKLLAS 549
Query: 73 QSY----------PSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRT 122
+++ P Q P+P P T P + ++ + II+ +L L +H T
Sbjct: 550 KAHGSEPPSVPGLPDQSSPVPRVPSPIAQATGSP-VQEEAIVIIQSALRAHLARARHSAT 608
>gi|45439333 porcupine isoform C [Homo sapiens]
Length = 455
Score = 33.9 bits (76), Expect = 0.37
Identities = 49/203 (24%), Positives = 78/203 (38%), Gaps = 29/203 (14%)
Query: 259 RGEGIQAPS---FSSYLYFL----FCPTLIYRE----TYPRTPYVRW-NYVAKNFAQALG 306
RGE PS F YLYF+ F P + + R RW VA++ A AL
Sbjct: 143 RGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALALL 202
Query: 307 C-VLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNA 365
C VL C +G P F ++ + + ++ L A + +F A
Sbjct: 203 CLVLSTC--VGPYLFPYFIPLNGDRLLRKGTMVRWLRAYESAVSFHFSNYFVGFLSEATA 260
Query: 366 FAEMLRFGDRMFYRDWWNSTS----------FSNYYRTWNVVVHDWLYSYVYQDGLRLLG 415
F + + +W + S +WN+ + WL +YV+++ LRL
Sbjct: 261 TLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRL-- 318
Query: 416 ARARGVAMLGVFLVSAVAHEYIF 438
A+L + SA+ H + F
Sbjct: 319 --GTFSAVLVTYAASALLHGFSF 339
>gi|18426913 drebrin 1 isoform b [Homo sapiens]
Length = 651
Score = 33.1 bits (74), Expect = 0.63
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 4/42 (9%)
Query: 56 AQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPS 97
A + E ++RA+ E S P PLPPPPP TQEPS
Sbjct: 346 ASTPVAEQIERALDEVTSSQPP---PLPPPPP-PAQETQEPS 383
>gi|18426915 drebrin 1 isoform a [Homo sapiens]
Length = 649
Score = 33.1 bits (74), Expect = 0.63
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 4/42 (9%)
Query: 56 AQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPS 97
A + E ++RA+ E S P PLPPPPP TQEPS
Sbjct: 344 ASTPVAEQIERALDEVTSSQPP---PLPPPPP-PAQETQEPS 381
>gi|239754630 PREDICTED: hypothetical protein [Homo sapiens]
Length = 377
Score = 32.7 bits (73), Expect = 0.83
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 28/115 (24%)
Query: 247 LREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALG 306
L EA+PG R G+G Q TY ++P V W Y KN +A+
Sbjct: 23 LEEAIPGKASFRAGKGRQG-------------------TYCKSPQVGW-YFGKNVKEAIK 62
Query: 307 CVLYACFILGRLCVPVFANMSREPFSTR----ALVLSILHATLPGIFMLLLIFFA 357
F+ G++ +P F + +R P + A+V S A+ PG L++ FA
Sbjct: 63 DRTGRGFLPGKV-IPPFPSPTRPPTHGKKIKTAVVASACAASSPG---ALIVAFA 113
>gi|239749175 PREDICTED: hypothetical protein XP_002346935 [Homo
sapiens]
Length = 377
Score = 32.7 bits (73), Expect = 0.83
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 28/115 (24%)
Query: 247 LREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALG 306
L EA+PG R G+G Q TY ++P V W Y KN +A+
Sbjct: 23 LEEAIPGKASFRAGKGRQG-------------------TYCKSPQVGW-YFGKNVKEAIK 62
Query: 307 CVLYACFILGRLCVPVFANMSREPFSTR----ALVLSILHATLPGIFMLLLIFFA 357
F+ G++ +P F + +R P + A+V S A+ PG L++ FA
Sbjct: 63 DRTGRGFLPGKV-IPPFPSPTRPPTHGKKIKTAVVASACAASSPG---ALIVAFA 113
>gi|239743250 PREDICTED: hypothetical protein XP_002342811 [Homo
sapiens]
Length = 377
Score = 32.7 bits (73), Expect = 0.83
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 28/115 (24%)
Query: 247 LREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALG 306
L EA+PG R G+G Q TY ++P V W Y KN +A+
Sbjct: 23 LEEAIPGKASFRAGKGRQG-------------------TYCKSPQVGW-YFGKNVKEAIK 62
Query: 307 CVLYACFILGRLCVPVFANMSREPFSTR----ALVLSILHATLPGIFMLLLIFFA 357
F+ G++ +P F + +R P + A+V S A+ PG L++ FA
Sbjct: 63 DRTGRGFLPGKV-IPPFPSPTRPPTHGKKIKTAVVASACAASSPG---ALIVAFA 113
>gi|239508925 PREDICTED: hypothetical protein [Homo sapiens]
Length = 377
Score = 32.7 bits (73), Expect = 0.83
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 28/115 (24%)
Query: 247 LREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALG 306
L EA+PG R G+G Q TY ++P V W Y KN +A+
Sbjct: 23 LEEAIPGKASFRAGKGRQG-------------------TYCKSPQVGW-YFGKNVKEAIK 62
Query: 307 CVLYACFILGRLCVPVFANMSREPFSTR----ALVLSILHATLPGIFMLLLIFFA 357
F+ G++ +P F + +R P + A+V S A+ PG L++ FA
Sbjct: 63 DRTGRGFLPGKV-IPPFPSPTRPPTHGKKIKTAVVASACAASSPG---ALIVAFA 113
>gi|31377722 PERP, TP53 apoptosis effector [Homo sapiens]
Length = 193
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 379 RDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIF 438
R W S+ W + S Y++G + L A G A + + +
Sbjct: 33 RGWLQSSDHGQTSSLWWKCSQEGGGSGSYEEGCQSLMEYAWGRAAAAMLFCGFII--LVI 90
Query: 439 CFVLGFFY---PVMLILFLVIGGML 460
CF+L FF P ML+ VIGG+L
Sbjct: 91 CFILSFFALCGPQMLVFLRVIGGLL 115
>gi|191252785 centrobin, centrosomal BRCA2 interacting protein
isoform alpha [Homo sapiens]
Length = 903
Score = 32.0 bits (71), Expect = 1.4
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 19 ERERQPCGDGNT----ETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQS 74
ER++Q D E R +L + +E + +L+E+ Q L+ D A + +
Sbjct: 512 ERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQAHWDEANQLLSTT 571
Query: 75 YPSQDKPLPPPPPGSLSRTQEPSLGKQKVF 104
P + P PP P S QEP +++V+
Sbjct: 572 LPPPNPPAPPAGPSS-PGPQEPEKEERRVW 600
>gi|80861396 centrobin, centrosomal BRCA2 interacting protein
isoform beta [Homo sapiens]
Length = 925
Score = 32.0 bits (71), Expect = 1.4
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 19 ERERQPCGDGNT----ETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQS 74
ER++Q D E R +L + +E + +L+E+ Q L+ D A + +
Sbjct: 512 ERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQAHWDEANQLLSTT 571
Query: 75 YPSQDKPLPPPPPGSLSRTQEPSLGKQKVF 104
P + P PP P S QEP +++V+
Sbjct: 572 LPPPNPPAPPAGPSS-PGPQEPEKEERRVW 600
>gi|57242782 MAX interactor 1 isoform a [Homo sapiens]
Length = 228
Score = 31.6 bits (70), Expect = 1.8
Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 15/80 (18%)
Query: 45 MEAVKA----QLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPP------PPGSLSRTQ 94
ME VK +LLE A E L+R RE Y S +P P PP LSR Q
Sbjct: 1 MERVKMINVQRLLEAA-----EFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQ 55
Query: 95 EPSLGKQKVFIIRKSLLDEL 114
+ S G +S +EL
Sbjct: 56 KHSSGSSNTSTANRSTHNEL 75
>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
member 1 interacting protein [Homo sapiens]
Length = 666
Score = 30.8 bits (68), Expect = 3.1
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 76 PSQDKPLPPPPPGSLSRTQEPSLGK 100
P D PLPPPPP LS+ +E + K
Sbjct: 135 PVLDLPLPPPPPEPLSQEEEEAQAK 159
>gi|45439337 porcupine isoform E [Homo sapiens]
Length = 379
Score = 30.8 bits (68), Expect = 3.1
Identities = 51/203 (25%), Positives = 76/203 (37%), Gaps = 34/203 (16%)
Query: 259 RGEGIQAPS---FSSYLYFL----FCPTLIYRE----TYPRTPYVRW-NYVAKNFAQALG 306
RGE PS F YLYF+ F P + + R RW VA++ A AL
Sbjct: 72 RGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALALL 131
Query: 307 C-VLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNA 365
C VL C +G P F P + L+ L A + +F A
Sbjct: 132 CLVLSTC--VGPYLFPYFI-----PLNGDRLLRKWLRAYESAVSFHFSNYFVGFLSEATA 184
Query: 366 FAEMLRFGDRMFYRDWWNSTS----------FSNYYRTWNVVVHDWLYSYVYQDGLRLLG 415
F + + +W + S +WN+ + WL +YV+++ LRL
Sbjct: 185 TLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRL-- 242
Query: 416 ARARGVAMLGVFLVSAVAHEYIF 438
A+L + SA+ H + F
Sbjct: 243 --GTFSAVLVTYAASALLHGFSF 263
>gi|45439329 porcupine isoform A [Homo sapiens]
Length = 450
Score = 30.8 bits (68), Expect = 3.1
Identities = 51/203 (25%), Positives = 76/203 (37%), Gaps = 34/203 (16%)
Query: 259 RGEGIQAPS---FSSYLYFL----FCPTLIYRE----TYPRTPYVRW-NYVAKNFAQALG 306
RGE PS F YLYF+ F P + + R RW VA++ A AL
Sbjct: 143 RGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALALL 202
Query: 307 C-VLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNA 365
C VL C +G P F P + L+ L A + +F A
Sbjct: 203 CLVLSTC--VGPYLFPYFI-----PLNGDRLLRKWLRAYESAVSFHFSNYFVGFLSEATA 255
Query: 366 FAEMLRFGDRMFYRDWWNSTS----------FSNYYRTWNVVVHDWLYSYVYQDGLRLLG 415
F + + +W + S +WN+ + WL +YV+++ LRL
Sbjct: 256 TLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRL-- 313
Query: 416 ARARGVAMLGVFLVSAVAHEYIF 438
A+L + SA+ H + F
Sbjct: 314 --GTFSAVLVTYAASALLHGFSF 334
>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
sapiens]
Length = 1135
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 411 LRLLG-ARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLV------IGGMLNFM 463
LR+ G ++A G + L +A+A I L P++ + FL+ + L +
Sbjct: 592 LRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTL 651
Query: 464 MHDQRTGPAWNVLMWTMLFLGQGIQVSL-YCQEWY 497
+ P + W + F+G I ++L + WY
Sbjct: 652 LRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 686
>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
sapiens]
Length = 1141
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 411 LRLLG-ARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLV------IGGMLNFM 463
LR+ G ++A G + L +A+A I L P++ + FL+ + L +
Sbjct: 598 LRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTL 657
Query: 464 MHDQRTGPAWNVLMWTMLFLGQGIQVSL-YCQEWY 497
+ P + W + F+G I ++L + WY
Sbjct: 658 LRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 692
>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 411 LRLLG-ARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLV------IGGMLNFM 463
LR+ G ++A G + L +A+A I L P++ + FL+ + L +
Sbjct: 548 LRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTL 607
Query: 464 MHDQRTGPAWNVLMWTMLFLGQGIQVSL-YCQEWY 497
+ P + W + F+G I ++L + WY
Sbjct: 608 LRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 642
>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 411 LRLLG-ARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLV------IGGMLNFM 463
LR+ G ++A G + L +A+A I L P++ + FL+ + L +
Sbjct: 548 LRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTL 607
Query: 464 MHDQRTGPAWNVLMWTMLFLGQGIQVSL-YCQEWY 497
+ P + W + F+G I ++L + WY
Sbjct: 608 LRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 642
>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
sapiens]
Length = 1099
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 411 LRLLG-ARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLV------IGGMLNFM 463
LR+ G ++A G + L +A+A I L P++ + FL+ + L +
Sbjct: 556 LRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTL 615
Query: 464 MHDQRTGPAWNVLMWTMLFLGQGIQVSL-YCQEWY 497
+ P + W + F+G I ++L + WY
Sbjct: 616 LRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 650
>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
sapiens]
Length = 1150
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 411 LRLLG-ARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLV------IGGMLNFM 463
LR+ G ++A G + L +A+A I L P++ + FL+ + L +
Sbjct: 607 LRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTL 666
Query: 464 MHDQRTGPAWNVLMWTMLFLGQGIQVSL-YCQEWY 497
+ P + W + F+G I ++L + WY
Sbjct: 667 LRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 701
>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
Length = 755
Score = 30.4 bits (67), Expect = 4.1
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 6/41 (14%)
Query: 73 QSYPSQDKPL---PPPPPGSLSRTQE---PSLGKQKVFIIR 107
QS P D+P PPPPPG L+R+ E P L ++ +R
Sbjct: 58 QSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVR 98
>gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]
Length = 560
Score = 30.4 bits (67), Expect = 4.1
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 6/41 (14%)
Query: 73 QSYPSQDKPL---PPPPPGSLSRTQE---PSLGKQKVFIIR 107
QS P D+P PPPPPG L+R+ E P L ++ +R
Sbjct: 58 QSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVR 98
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 30.0 bits (66), Expect = 5.4
Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 36 PDLVQWTRHMEAVKAQLLEQAQGQLRE--LLDRAMREAIQSYPSQDKPLPPPPPGSLSRT 93
PDL +AQL + +L + D+ EA++ + +PLPPPPP S
Sbjct: 265 PDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGN 324
Query: 94 QEP 96
Q P
Sbjct: 325 QLP 327
>gi|10834994 interleukin 11 precursor [Homo sapiens]
Length = 199
Score = 30.0 bits (66), Expect = 5.4
Identities = 17/49 (34%), Positives = 20/49 (40%)
Query: 39 VQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPP 87
VQW R + LE G L+ LDR +R P PPP P
Sbjct: 108 VQWLRRAGGSSLKTLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDP 156
>gi|219689113 two pore segment channel 1 isoform 1 [Homo sapiens]
Length = 888
Score = 30.0 bits (66), Expect = 5.4
Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 141 IDFIDEGRLLLEFDLLIFSF-GQLPLALVTWVPMFLSTLLAPYQALRLW 188
++++ G L +F + +F+F G L LAL P + +L P Q LRL+
Sbjct: 572 VEYLSSGWNLFDFSVTVFAFLGLLALAL-NMEPFYFIVVLRPLQLLRLF 619
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.142 0.470
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,136,716
Number of Sequences: 37866
Number of extensions: 965899
Number of successful extensions: 6408
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 6303
Number of HSP's gapped (non-prelim): 114
length of query: 522
length of database: 18,247,518
effective HSP length: 107
effective length of query: 415
effective length of database: 14,195,856
effective search space: 5891280240
effective search space used: 5891280240
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.