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Search of human proteins with 4507091
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507091 survival of motor neuron 1, telomeric isoform d
[Homo sapiens]
(294 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10937869 survival of motor neuron 2, centromeric isoform d [H... 629 0.0
gi|4507091 survival of motor neuron 1, telomeric isoform d [Homo... 629 0.0
gi|13259527 survival of motor neuron 2, centromeric isoform a [H... 595 e-170
gi|13259529 survival of motor neuron 2, centromeric isoform b [H... 534 e-152
gi|13259512 survival of motor neuron 1, telomeric isoform b [Hom... 534 e-152
gi|13259531 survival of motor neuron 2, centromeric isoform c [H... 499 e-142
gi|157168329 formin 1 [Homo sapiens] 64 1e-10
gi|33356148 formin-like 1 [Homo sapiens] 62 5e-10
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 61 1e-09
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 61 1e-09
gi|210032580 SET domain containing 1B [Homo sapiens] 60 2e-09
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 60 2e-09
gi|5032113 survival motor neuron domain containing 1 [Homo sapiens] 60 2e-09
gi|160707881 formin 2 [Homo sapiens] 60 3e-09
gi|56549694 enabled homolog isoform a [Homo sapiens] 59 4e-09
gi|39930375 enabled homolog isoform b [Homo sapiens] 59 4e-09
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] 58 9e-09
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] 58 9e-09
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 57 1e-08
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 57 1e-08
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 57 2e-08
gi|55741677 SET domain containing 1A [Homo sapiens] 57 2e-08
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 57 3e-08
gi|150417989 cyclin K isoform 1 [Homo sapiens] 55 6e-08
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 55 7e-08
gi|11386183 WAS protein family, member 2 [Homo sapiens] 55 1e-07
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 55 1e-07
gi|153792074 proline rich 12 [Homo sapiens] 54 1e-07
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 54 2e-07
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 54 2e-07
>gi|10937869 survival of motor neuron 2, centromeric isoform d [Homo
sapiens]
Length = 294
Score = 629 bits (1623), Expect = 0.0
Identities = 294/294 (100%), Positives = 294/294 (100%)
Query: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC
Sbjct: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
Query: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR
Sbjct: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
Query: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS
Sbjct: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
Query: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP 240
DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP
Sbjct: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP 240
Query: 241 PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN 294
PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
Sbjct: 241 PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN 294
>gi|4507091 survival of motor neuron 1, telomeric isoform d [Homo
sapiens]
Length = 294
Score = 629 bits (1623), Expect = 0.0
Identities = 294/294 (100%), Positives = 294/294 (100%)
Query: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC
Sbjct: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
Query: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR
Sbjct: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
Query: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS
Sbjct: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
Query: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP 240
DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP
Sbjct: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP 240
Query: 241 PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN 294
PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
Sbjct: 241 PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN 294
>gi|13259527 survival of motor neuron 2, centromeric isoform a [Homo
sapiens]
Length = 282
Score = 595 bits (1534), Expect = e-170
Identities = 278/278 (100%), Positives = 278/278 (100%)
Query: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC
Sbjct: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
Query: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR
Sbjct: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
Query: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS
Sbjct: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
Query: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP 240
DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP
Sbjct: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP 240
Query: 241 PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYM 278
PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYM
Sbjct: 241 PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYM 278
>gi|13259529 survival of motor neuron 2, centromeric isoform b [Homo
sapiens]
Length = 262
Score = 534 bits (1375), Expect = e-152
Identities = 262/294 (89%), Positives = 262/294 (89%), Gaps = 32/294 (10%)
Query: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC
Sbjct: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
Query: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR
Sbjct: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
Query: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS
Sbjct: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
Query: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP 240
DNIKPKSAPWNSFLPPPPPMPGPRLGPGK
Sbjct: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGK------------------------------- 209
Query: 241 PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN 294
IIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
Sbjct: 210 -IIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN 262
>gi|13259512 survival of motor neuron 1, telomeric isoform b [Homo
sapiens]
Length = 262
Score = 534 bits (1375), Expect = e-152
Identities = 262/294 (89%), Positives = 262/294 (89%), Gaps = 32/294 (10%)
Query: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC
Sbjct: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
Query: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR
Sbjct: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
Query: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS
Sbjct: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
Query: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP 240
DNIKPKSAPWNSFLPPPPPMPGPRLGPGK
Sbjct: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGK------------------------------- 209
Query: 241 PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN 294
IIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
Sbjct: 210 -IIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN 262
>gi|13259531 survival of motor neuron 2, centromeric isoform c [Homo
sapiens]
Length = 250
Score = 499 bits (1286), Expect = e-142
Identities = 246/278 (88%), Positives = 246/278 (88%), Gaps = 32/278 (11%)
Query: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC
Sbjct: 1 MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDIC 60
Query: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR
Sbjct: 61 ETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKR 120
Query: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS
Sbjct: 121 ETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKS 180
Query: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGP 240
DNIKPKSAPWNSFLPPPPPMPGPRLGPGK
Sbjct: 181 DNIKPKSAPWNSFLPPPPPMPGPRLGPGK------------------------------- 209
Query: 241 PIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYM 278
IIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYM
Sbjct: 210 -IIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYM 246
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 64.3 bits (155), Expect = 1e-10
Identities = 30/58 (51%), Positives = 32/58 (55%), Gaps = 7/58 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICP 251
LPPPPP P P P G PPPPPPPP L + PP P GPP PPPP + P
Sbjct: 680 LPPPPPPPPPLPPPSSAG-------PPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAP 730
Score = 52.0 bits (123), Expect = 6e-07
Identities = 29/64 (45%), Positives = 33/64 (51%), Gaps = 12/64 (18%)
Query: 195 PPPPPMPGP--------RLGPGKPGLKFN-GPPPPPPPPPPHLLSCWLPPFPSGPPIIPP 245
PPP +P P L P P + GPP PPPPPPP L PP +GPP PP
Sbjct: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLP---PPSSAGPPPPPP 703
Query: 246 PPPI 249
PPP+
Sbjct: 704 PPPL 707
Score = 43.1 bits (100), Expect = 3e-04
Identities = 31/75 (41%), Positives = 32/75 (42%), Gaps = 12/75 (16%)
Query: 185 PKSAPWNSFLPPPPPMPGP---RLGPGKPGLKFNGPPPPPP-----PPPPHLLSCWLPPF 236
P P +S PPPPP P P P PG GPPP PP PPPP L L
Sbjct: 688 PPLPPPSSAGPPPPPPPPPLPNSPAPPNPG----GPPPAPPPPGLAPPPPPGLFFGLGSS 743
Query: 237 PSGPPIIPPPPPICP 251
S P P P CP
Sbjct: 744 SSQCPRKPAIEPSCP 758
Score = 39.7 bits (91), Expect = 0.003
Identities = 21/44 (47%), Positives = 24/44 (54%), Gaps = 9/44 (20%)
Query: 217 PPPPPP-PPPPHLLSCW--------LPPFPSGPPIIPPPPPICP 251
PPPP PPPP L S +PP +GPP+ PPPPP P
Sbjct: 646 PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPP 689
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 62.4 bits (150), Expect = 5e-10
Identities = 37/84 (44%), Positives = 41/84 (48%), Gaps = 8/84 (9%)
Query: 176 PGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPP 235
PG S P SAP P PP+PG P P L + PPPPPPPPPP P
Sbjct: 549 PGLPSPQEAPPSAP-----PQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTD---GP 600
Query: 236 FPSGPPIIPPPPPICPDSLDDADA 259
P PP PPPP PD+L D+
Sbjct: 601 VPPPPPPPPPPPGGPPDALGRRDS 624
Score = 42.0 bits (97), Expect = 6e-04
Identities = 37/124 (29%), Positives = 46/124 (37%), Gaps = 38/124 (30%)
Query: 165 VSTDESENSRSPGNKSDNIKPKSAPW-----NSFLPPPPPMPGPRLGPGKPGLKFNGPPP 219
V+T ++ +PG + + P AP + PPPPP+PG P
Sbjct: 508 VATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPG-----------LPSPQE 556
Query: 220 PPP--------------PPPPHLLSCWLPPFPSGP--------PIIPPPPPICPDSLDDA 257
PP PPP L LPP P P P+ PPPPP P
Sbjct: 557 APPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPP 616
Query: 258 DALG 261
DALG
Sbjct: 617 DALG 620
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 61.2 bits (147), Expect = 1e-09
Identities = 35/78 (44%), Positives = 39/78 (50%), Gaps = 15/78 (19%)
Query: 185 PKSAPWNSFLPPPPPMPG----PRLGPGKPGLKFNGPPPPP--------PPPPPHLLSCW 232
P S P + +PPPPP+PG P P PG PPPPP PPPPP
Sbjct: 657 PSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 716
Query: 233 L---PPFPSGPPIIPPPP 247
+ PPFP GP I PPPP
Sbjct: 717 IPPPPPFPGGPGIPPPPP 734
Score = 56.6 bits (135), Expect = 3e-08
Identities = 39/129 (30%), Positives = 54/129 (41%), Gaps = 27/129 (20%)
Query: 135 EQNLSDLLSPICEVANNIEQNAQENENESQ--VSTDESENSRSP--------GNKSDNIK 184
E +S L + ++ +E +E + S ++ S SR+P G+ I
Sbjct: 529 EAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIP 588
Query: 185 PKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIP 244
P AP +S PPPPP PPPPPPPP P + PP G I
Sbjct: 589 PPPAPGDSTTPPPPP-----------------PPPPPPPPLPGGVCISSPPSLPGGTAIS 631
Query: 245 PPPPICPDS 253
PPPP+ D+
Sbjct: 632 PPPPLSGDA 640
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/144 (29%), Positives = 58/144 (40%), Gaps = 32/144 (22%)
Query: 135 EQNLSDLLSPICEVANNIEQNAQENEN-ESQVSTDESENSRSPGNKSDNIK--------- 184
EQ L DL + + +Q A E ++ E++VS E ++ D K
Sbjct: 501 EQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAA 560
Query: 185 ---PKSAPWNSFLPPPPPMPGPR--LGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSG 239
P S P + +PP PP+PG + P P + PPPPPPPP
Sbjct: 561 ITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP-------------- 606
Query: 240 PPIIPPPPPIC---PDSLDDADAL 260
PP P P +C P SL A+
Sbjct: 607 PPPPPLPGGVCISSPPSLPGGTAI 630
Score = 42.7 bits (99), Expect = 4e-04
Identities = 28/72 (38%), Positives = 29/72 (40%), Gaps = 15/72 (20%)
Query: 176 PGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPP 235
PG P P +PPPPP PG GPG P PPP PPP PP
Sbjct: 699 PGEAGMPPPPPPLPGGPGIPPPPPFPG---GPGIP-----PPPPGMGMPPP-------PP 743
Query: 236 FPSGPPIIPPPP 247
F G P P P
Sbjct: 744 FGFGVPAAPVLP 755
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 61.2 bits (147), Expect = 1e-09
Identities = 35/78 (44%), Positives = 39/78 (50%), Gaps = 15/78 (19%)
Query: 185 PKSAPWNSFLPPPPPMPG----PRLGPGKPGLKFNGPPPPP--------PPPPPHLLSCW 232
P S P + +PPPPP+PG P P PG PPPPP PPPPP
Sbjct: 666 PSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 725
Query: 233 L---PPFPSGPPIIPPPP 247
+ PPFP GP I PPPP
Sbjct: 726 IPPPPPFPGGPGIPPPPP 743
Score = 56.6 bits (135), Expect = 3e-08
Identities = 39/129 (30%), Positives = 54/129 (41%), Gaps = 27/129 (20%)
Query: 135 EQNLSDLLSPICEVANNIEQNAQENENESQ--VSTDESENSRSP--------GNKSDNIK 184
E +S L + ++ +E +E + S ++ S SR+P G+ I
Sbjct: 538 EAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIP 597
Query: 185 PKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIP 244
P AP +S PPPPP PPPPPPPP P + PP G I
Sbjct: 598 PPPAPGDSTTPPPPP-----------------PPPPPPPPLPGGVCISSPPSLPGGTAIS 640
Query: 245 PPPPICPDS 253
PPPP+ D+
Sbjct: 641 PPPPLSGDA 649
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/144 (29%), Positives = 58/144 (40%), Gaps = 32/144 (22%)
Query: 135 EQNLSDLLSPICEVANNIEQNAQENEN-ESQVSTDESENSRSPGNKSDNIK--------- 184
EQ L DL + + +Q A E ++ E++VS E ++ D K
Sbjct: 510 EQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAA 569
Query: 185 ---PKSAPWNSFLPPPPPMPGPR--LGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSG 239
P S P + +PP PP+PG + P P + PPPPPPPP
Sbjct: 570 ITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP-------------- 615
Query: 240 PPIIPPPPPIC---PDSLDDADAL 260
PP P P +C P SL A+
Sbjct: 616 PPPPPLPGGVCISSPPSLPGGTAI 639
Score = 42.7 bits (99), Expect = 4e-04
Identities = 28/72 (38%), Positives = 29/72 (40%), Gaps = 15/72 (20%)
Query: 176 PGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPP 235
PG P P +PPPPP PG GPG P PPP PPP PP
Sbjct: 708 PGEAGMPPPPPPLPGGPGIPPPPPFPG---GPGIP-----PPPPGMGMPPP-------PP 752
Query: 236 FPSGPPIIPPPP 247
F G P P P
Sbjct: 753 FGFGVPAAPVLP 764
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 60.5 bits (145), Expect = 2e-09
Identities = 31/59 (52%), Positives = 34/59 (57%), Gaps = 5/59 (8%)
Query: 194 LPPPPPMPGPRLG-PGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICP 251
LPPPPP P P+ G P P L PPPPPPPPP H PP PP +PPPP + P
Sbjct: 690 LPPPPPPPPPQPGFPMPPPL----PPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPP 744
Score = 53.9 bits (128), Expect = 2e-07
Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 25/125 (20%)
Query: 140 DLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPK---------SAPW 190
DL+ + +++ Q + + ++S DE ++ P +D KP +AP
Sbjct: 616 DLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSA--PITSADCPKPMVVTPGAAAVAAP- 672
Query: 191 NSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPP------PPHLLSCWLPPFPSGPPIIP 244
S L P P+P P PG P L PPPPPPPP PP L PP P+ P +
Sbjct: 673 -SVLAPTLPLPPP---PGFPPLP---PPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTV 725
Query: 245 PPPPI 249
PPPP+
Sbjct: 726 PPPPL 730
Score = 45.1 bits (105), Expect = 8e-05
Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 13/68 (19%)
Query: 185 PKSAPWNSF-LPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPII 243
P P F +PPP P P P P P + PPPP P PP +PP PPI+
Sbjct: 695 PPPPPQPGFPMPPPLPPPPPPPPPAHPAVTV--PPPPLPAPP------GVPP----PPIL 742
Query: 244 PPPPPICP 251
PP PP P
Sbjct: 743 PPLPPFPP 750
Score = 37.4 bits (85), Expect = 0.016
Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 3/71 (4%)
Query: 175 SPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLP 234
+PG KS P P F PPP + +F P PPP PP L+ P
Sbjct: 390 APGFKSA-FSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKP 448
Query: 235 PFPSGPPIIPP 245
P GPP PP
Sbjct: 449 GTPPGPP--PP 457
Score = 34.7 bits (78), Expect = 0.10
Identities = 23/60 (38%), Positives = 24/60 (40%), Gaps = 11/60 (18%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSL 254
P P P P L F P PPPP LPP P PP PPPP+ P L
Sbjct: 1513 PQTPVFPSTH-DPRTVTLDFRNAGIPAPPPP-------LPPQPPPPP---PPPPVEPTKL 1561
Score = 34.7 bits (78), Expect = 0.10
Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 24/64 (37%)
Query: 191 NSFLP-PPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLP------PFPSGPPII 243
N+ +P PPPP+P P PPPPPPPP + LP +PS I
Sbjct: 1533 NAGIPAPPPPLP---------------PQPPPPPPPPPVEPTKLPFKELDNQWPS--EAI 1575
Query: 244 PPPP 247
PP P
Sbjct: 1576 PPGP 1579
Score = 32.3 bits (72), Expect = 0.51
Identities = 30/114 (26%), Positives = 38/114 (33%), Gaps = 18/114 (15%)
Query: 160 ENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPR------LGPGKPGLK 213
E E + T+ P + P + PP PG L P P +
Sbjct: 1188 EEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKE 1247
Query: 214 FNGPPPPPP-----------PPPPHLLSCWL-PPFPSGPPIIPPPPPICPDSLD 255
PP P P PP +L L PP P P PP PP P++ D
Sbjct: 1248 VEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTD 1301
Score = 32.3 bits (72), Expect = 0.51
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 8/57 (14%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPIC 250
LP PP+P PR P +P P PPP P +PP P P P +C
Sbjct: 1276 LPLQPPLPPPR--PPRP------PSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLC 1324
Score = 30.0 bits (66), Expect = 2.5
Identities = 15/33 (45%), Positives = 16/33 (48%), Gaps = 5/33 (15%)
Query: 216 GPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPP 248
G P PPPP PP PP P PP+ P P
Sbjct: 1535 GIPAPPPPLPPQP-----PPPPPPPPVEPTKLP 1562
Score = 29.6 bits (65), Expect = 3.3
Identities = 23/62 (37%), Positives = 25/62 (40%), Gaps = 2/62 (3%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDS 253
LP P P+P P P + P P PP P L SC PP P P P S
Sbjct: 1431 LPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASC--PPPMKRKPGRPRRSPPSMLS 1488
Query: 254 LD 255
LD
Sbjct: 1489 LD 1490
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 60.1 bits (144), Expect = 2e-09
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 11/110 (10%)
Query: 161 NESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPP 220
++++ ++ + + N PK P LP PP PGP+ G G PPP
Sbjct: 484 DDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPQAPTSPNGRPMQGGPPP 543
Query: 221 PPPPPPHLLSCWLPPFPSGPPIIPPP--PPICPDSLDDADALGSMLISWY 268
PPPPPP P GPP +P P P+ P L D + S +
Sbjct: 544 PPPPPPP---------PPGPPQMPMPVHEPLSPQQLQQQDMYNKKIPSLF 584
Score = 37.4 bits (85), Expect = 0.016
Identities = 20/41 (48%), Positives = 21/41 (51%), Gaps = 13/41 (31%)
Query: 216 GPPPPPP---PPPPHLLSCWLPPFPSGPPIIPPPPPICPDS 253
G PPPPP PPPP PP PP P PPP PD+
Sbjct: 6 GTPPPPPSESPPPPS------PP----PPSTPSPPPCSPDA 36
Score = 34.7 bits (78), Expect = 0.10
Identities = 26/81 (32%), Positives = 32/81 (39%), Gaps = 15/81 (18%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHL---------LSCWLPPFPS---GPPI 242
PP P PGP +GP P GP P P H + +P P GPP+
Sbjct: 608 PPGPMGPGPNMGPPGP---MGGPMHPDMHPDMHPDMHPDMHADMHADMPMGPGMNPGPPM 664
Query: 243 IPPPPPICPDSLDDADALGSM 263
P PP+ P D+ G M
Sbjct: 665 GPGGPPMMPYGPGDSPHSGMM 685
Score = 34.3 bits (77), Expect = 0.13
Identities = 19/48 (39%), Positives = 20/48 (41%), Gaps = 8/48 (16%)
Query: 207 PGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSL 254
PG P + PPPP PPPP PS PP P P P L
Sbjct: 5 PGTPPPPPSESPPPPSPPPPST--------PSPPPCSPDARPATPHLL 44
Score = 33.5 bits (75), Expect = 0.23
Identities = 20/64 (31%), Positives = 26/64 (40%), Gaps = 13/64 (20%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSL 254
PPPPP P PP PPPP P C P+ P ++ P+ PD
Sbjct: 8 PPPPPSESPP------------PPSPPPPSTPSPPPCSPDARPATPHLLHHRLPL-PDDR 54
Query: 255 DDAD 258
+D +
Sbjct: 55 EDGE 58
Score = 32.7 bits (73), Expect = 0.39
Identities = 35/130 (26%), Positives = 43/130 (33%), Gaps = 49/130 (37%)
Query: 174 RSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPG------------------------- 208
R PG ++ P P PPPPP P P GP
Sbjct: 522 RPPGPQAPT-SPNGRPMQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQDMYNKKI 580
Query: 209 ----------------KPGLKFNGP--PPPPPPPPPHLLSCWLPPFPSGPPIIPP-PPPI 249
K G++F GP PP P P P++ PP P G P+ P P +
Sbjct: 581 PSLFEIVVRPTGQLAEKLGVRFPGPGGPPGPMGPGPNM----GPPGPMGGPMHPDMHPDM 636
Query: 250 CPDSLDDADA 259
PD D A
Sbjct: 637 HPDMHPDMHA 646
Score = 30.0 bits (66), Expect = 2.5
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 6/45 (13%)
Query: 188 APWNSFLPPPPPM-PGPRLGPGKPGLKFNGPPPPP-----PPPPP 226
A ++ +P P M PGP +GPG P + GP P PP PP
Sbjct: 646 ADMHADMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPP 690
>gi|5032113 survival motor neuron domain containing 1 [Homo sapiens]
Length = 238
Score = 60.1 bits (144), Expect = 2e-09
Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
Query: 92 WKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPICEVANN 151
WKVGDKC A+WSEDG Y A I ID + T + + GYGN E L + L P+ E
Sbjct: 73 WKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLN-LKPVEEGRKA 131
Query: 152 IEQNAQENENESQVSTDESENSRSPG-NKSDNIK 184
E + + ++ ++ + E + K+ IK
Sbjct: 132 KEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIK 165
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 59.7 bits (143), Expect = 3e-09
Identities = 31/63 (49%), Positives = 37/63 (58%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P + IPPP
Sbjct: 1052 IPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1110
Query: 247 PPI 249
PP+
Sbjct: 1111 PPL 1113
Score = 59.3 bits (142), Expect = 4e-09
Identities = 31/63 (49%), Positives = 37/63 (58%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P + IPPP
Sbjct: 1096 IPPPPPLPGVGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154
Query: 247 PPI 249
PP+
Sbjct: 1155 PPL 1157
Score = 59.3 bits (142), Expect = 4e-09
Identities = 29/62 (46%), Positives = 36/62 (58%), Gaps = 6/62 (9%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPP-----PPPPPHLLSCWLPPFPSGPPI-IPPPP 247
+PPPPP+PG + P P + PPPPP PPPP L +PP P P + IPPPP
Sbjct: 1129 IPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1188
Query: 248 PI 249
P+
Sbjct: 1189 PL 1190
Score = 58.5 bits (140), Expect = 7e-09
Identities = 33/71 (46%), Positives = 40/71 (56%), Gaps = 13/71 (18%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPIIP--- 244
+PPPPP+PG + P P L G PPPPP PPPP L +PP P+ PP+ P
Sbjct: 1173 IPPPPPLPGVGIPPPPP-LPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA-PPLPPPGT 1230
Query: 245 --PPPPICPDS 253
PPPP+ P S
Sbjct: 1231 GIPPPPLLPVS 1241
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 975 IPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1033
Query: 247 PPI 249
PP+
Sbjct: 1034 PPL 1036
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 986 IPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1044
Query: 247 PPI 249
PP+
Sbjct: 1045 PPL 1047
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 997 IPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1055
Query: 247 PPI 249
PP+
Sbjct: 1056 PPL 1058
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 1008 IPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1066
Query: 247 PPI 249
PP+
Sbjct: 1067 PPL 1069
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 1019 IPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1077
Query: 247 PPI 249
PP+
Sbjct: 1078 PPL 1080
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 1030 IPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1088
Query: 247 PPI 249
PP+
Sbjct: 1089 PPL 1091
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 1041 IPPPPPLPGAGI-PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1099
Query: 247 PPI 249
PP+
Sbjct: 1100 PPL 1102
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 1074 IPPPPPLPGAGI-PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1132
Query: 247 PPI 249
PP+
Sbjct: 1133 PPL 1135
Score = 58.2 bits (139), Expect = 9e-09
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 1118 IPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1176
Query: 247 PPI 249
PP+
Sbjct: 1177 PPL 1179
Score = 57.8 bits (138), Expect = 1e-08
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 1063 IPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPP 1121
Query: 247 PPI 249
PP+
Sbjct: 1122 PPL 1124
Score = 57.8 bits (138), Expect = 1e-08
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 1085 IPPPPPLPGAGIPPPPP-LPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1143
Query: 247 PPI 249
PP+
Sbjct: 1144 PPL 1146
Score = 57.4 bits (137), Expect = 1e-08
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 953 IPPPPPLPGAGI-PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1011
Query: 247 PPI 249
PP+
Sbjct: 1012 PPL 1014
Score = 57.4 bits (137), Expect = 1e-08
Identities = 31/63 (49%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 1107 IPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP 1165
Query: 247 PPI 249
PP+
Sbjct: 1166 PPL 1168
Score = 54.7 bits (130), Expect = 1e-07
Identities = 30/63 (47%), Positives = 35/63 (55%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+PPPPP+PG + P P L G P PPP PPPP L +PP P P IPPP
Sbjct: 942 IPPPPPLPGAAIPPPPP-LPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1000
Query: 247 PPI 249
PP+
Sbjct: 1001 PPL 1003
Score = 54.3 bits (129), Expect = 1e-07
Identities = 30/63 (47%), Positives = 35/63 (55%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLPPFPSGPPI-IPPP 246
+P PPP+PG + P P L G PPPPP PPPP L +PP P P IPPP
Sbjct: 964 IPLPPPLPGAGI-PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1022
Query: 247 PPI 249
PP+
Sbjct: 1023 PPL 1025
Score = 53.1 bits (126), Expect = 3e-07
Identities = 30/63 (47%), Positives = 35/63 (55%), Gaps = 8/63 (12%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPP------PPPPHLLSCWLP-PFPSGPPIIPPP 246
+PPPPP+PG + P P L G PPPPP PPPP L +P P P IPPP
Sbjct: 920 IPPPPPLPGAGILP-LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP 978
Query: 247 PPI 249
PP+
Sbjct: 979 PPL 981
Score = 50.1 bits (118), Expect = 2e-06
Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 13/68 (19%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFP----SGPPIIP----- 244
+PPPPP+PG + P P PP P PP PP +PP P SGPP++P
Sbjct: 1195 IPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPP--GTGIPPPPLLPVSGPPLLPQVGSS 1252
Query: 245 --PPPPIC 250
P P +C
Sbjct: 1253 TLPTPQVC 1260
Score = 49.3 bits (116), Expect = 4e-06
Identities = 32/71 (45%), Positives = 36/71 (50%), Gaps = 16/71 (22%)
Query: 195 PPPPPMPG---PRLG----PGKPGLKFNG--PPPPPP------PPPPHLLSCWLPPFPSG 239
PPPPP+PG P L P P L+ PPPPPP PPPP L + P P
Sbjct: 878 PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPL 937
Query: 240 PPI-IPPPPPI 249
P IPPPPP+
Sbjct: 938 PGAGIPPPPPL 948
Score = 48.5 bits (114), Expect = 7e-06
Identities = 29/74 (39%), Positives = 34/74 (45%), Gaps = 20/74 (27%)
Query: 194 LPPPPPMPGPRLGPGKPGLKFNGPPPPP--------------PPPPPHLLSCWLPPFPSG 239
+P PPP+P PGL PPPPP P PPP + LPP P
Sbjct: 855 IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPP-- 912
Query: 240 PPI----IPPPPPI 249
PP+ IPPPPP+
Sbjct: 913 PPLPGAGIPPPPPL 926
Score = 36.6 bits (83), Expect = 0.027
Identities = 30/107 (28%), Positives = 35/107 (32%), Gaps = 50/107 (46%)
Query: 195 PPPPPMPGPRLGPGKPGLK------------------------FNGPPPPP--------- 221
PPPPP G G+PG + N P PPP
Sbjct: 810 PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSS 869
Query: 222 -------PPPPPHLLSCWLPPFPS----------GPPIIPPPPPICP 251
PPPPP L +P PS G ++PPPPP P
Sbjct: 870 MPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP 916
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 59.3 bits (142), Expect = 4e-09
Identities = 30/60 (50%), Positives = 33/60 (55%), Gaps = 8/60 (13%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPI---IPPPPPICP 251
PPPPP+P PG PPPP PPPPP L S PP P PP+ +PPPPP P
Sbjct: 314 PPPPPLP-----PGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/125 (32%), Positives = 51/125 (40%), Gaps = 23/125 (18%)
Query: 147 EVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSA--PWNSFL-------PPP 197
E +E+ QE E + Q+ ++ E R S P S P NS L P
Sbjct: 233 ERLERLERERQERERQEQLEREQLEWERER-RISSAAAPASVETPLNSVLGDSSASEPGL 291
Query: 198 PPMPGPRLGPGKPGLKFN--GPPPPPP-PPPPHLLSCWLPPFP----------SGPPIIP 244
P P + G+ PPPPPP PP P S LPP P +GPP P
Sbjct: 292 QAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPP 351
Query: 245 PPPPI 249
PPPP+
Sbjct: 352 PPPPL 356
Score = 46.6 bits (109), Expect = 3e-05
Identities = 25/55 (45%), Positives = 27/55 (49%), Gaps = 7/55 (12%)
Query: 176 PGNKSDNIKPKSAPWNSFLPPPPPMP--GPRLGPGKPGLKFNGPPPPPPPPPPHL 228
P S + P P PPPPP+P GP P P L PPPPPPPP P L
Sbjct: 323 PAQASVALPPPPGP-----PPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPL 372
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 59.3 bits (142), Expect = 4e-09
Identities = 30/60 (50%), Positives = 33/60 (55%), Gaps = 8/60 (13%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPI---IPPPPPICP 251
PPPPP+P PG PPPP PPPPP L S PP P PP+ +PPPPP P
Sbjct: 314 PPPPPLP-----PGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/125 (32%), Positives = 51/125 (40%), Gaps = 23/125 (18%)
Query: 147 EVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSA--PWNSFL-------PPP 197
E +E+ QE E + Q+ ++ E R S P S P NS L P
Sbjct: 233 ERLERLERERQERERQEQLEREQLEWERER-RISSAAAPASVETPLNSVLGDSSASEPGL 291
Query: 198 PPMPGPRLGPGKPGLKFN--GPPPPPP-PPPPHLLSCWLPPFP----------SGPPIIP 244
P P + G+ PPPPPP PP P S LPP P +GPP P
Sbjct: 292 QAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPP 351
Query: 245 PPPPI 249
PPPP+
Sbjct: 352 PPPPL 356
Score = 46.6 bits (109), Expect = 3e-05
Identities = 25/55 (45%), Positives = 27/55 (49%), Gaps = 7/55 (12%)
Query: 176 PGNKSDNIKPKSAPWNSFLPPPPPMP--GPRLGPGKPGLKFNGPPPPPPPPPPHL 228
P S + P P PPPPP+P GP P P L PPPPPPPP P L
Sbjct: 323 PAQASVALPPPPGP-----PPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPL 372
>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
Length = 849
Score = 58.2 bits (139), Expect = 9e-09
Identities = 35/99 (35%), Positives = 52/99 (52%), Gaps = 16/99 (16%)
Query: 153 EQNAQENENESQVSTDESENSRSPGNKSDNIKP--KSAPWNSFLPPPPPMPGPRLGPGKP 210
++ A+ NE ++++ +S+ P + + + P + +S LPPPPP+P
Sbjct: 269 KKEAKINELQAELQAFKSQFGALPADCNIPLPPSKEGGTGHSALPPPPPLPSG------- 321
Query: 211 GLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPI 249
G PPPPPPPPP L PF SGP +PPPPP+
Sbjct: 322 ----GGVPPPPPPPPPPPLPGMRMPF-SGP--VPPPPPL 353
Score = 33.5 bits (75), Expect = 0.23
Identities = 29/94 (30%), Positives = 33/94 (35%), Gaps = 21/94 (22%)
Query: 167 TDESENSRSPGNKSDNIKPKSAPWNSF------LPPPPPMPGPRLGPGKPGLKFNGPPPP 220
TD E K I A +F LP +P P P K G + PP
Sbjct: 258 TDHQETQAELQKKEAKINELQAELQAFKSQFGALPADCNIPLP---PSKEGGTGHSALPP 314
Query: 221 PPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSL 254
PPP PSG + PPPPP P L
Sbjct: 315 PPP------------LPSGGGVPPPPPPPPPPPL 336
>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
Length = 1193
Score = 58.2 bits (139), Expect = 9e-09
Identities = 35/99 (35%), Positives = 52/99 (52%), Gaps = 16/99 (16%)
Query: 153 EQNAQENENESQVSTDESENSRSPGNKSDNIKP--KSAPWNSFLPPPPPMPGPRLGPGKP 210
++ A+ NE ++++ +S+ P + + + P + +S LPPPPP+P
Sbjct: 532 KKEAKINELQAELQAFKSQFGALPADCNIPLPPSKEGGTGHSALPPPPPLPSG------- 584
Query: 211 GLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPI 249
G PPPPPPPPP L PF SGP +PPPPP+
Sbjct: 585 ----GGVPPPPPPPPPPPLPGMRMPF-SGP--VPPPPPL 616
Score = 33.5 bits (75), Expect = 0.23
Identities = 29/94 (30%), Positives = 33/94 (35%), Gaps = 21/94 (22%)
Query: 167 TDESENSRSPGNKSDNIKPKSAPWNSF------LPPPPPMPGPRLGPGKPGLKFNGPPPP 220
TD E K I A +F LP +P P P K G + PP
Sbjct: 521 TDHQETQAELQKKEAKINELQAELQAFKSQFGALPADCNIPLP---PSKEGGTGHSALPP 577
Query: 221 PPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSL 254
PPP PSG + PPPPP P L
Sbjct: 578 PPP------------LPSGGGVPPPPPPPPPPPL 599
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 57.4 bits (137), Expect = 1e-08
Identities = 35/72 (48%), Positives = 38/72 (52%), Gaps = 21/72 (29%)
Query: 195 PPPPPMPG--------PRLGPGKPG-LKFNGPPPPP------PPPPPHLLSCWLPPFPSG 239
PPPPP+PG P L P PG +F PPPPP PPPPP LL P G
Sbjct: 458 PPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLL----PGMGWG 513
Query: 240 PPIIPPPPPICP 251
PP PPPPP+ P
Sbjct: 514 PP--PPPPPLLP 523
Score = 55.1 bits (131), Expect = 7e-08
Identities = 29/74 (39%), Positives = 37/74 (50%), Gaps = 11/74 (14%)
Query: 184 KPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPI- 242
+P++ + PPPPP P P PG PPPPPPPP P + + LP P PP+
Sbjct: 410 QPRALEQQASTPPPPPPP-----PLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLP 464
Query: 243 -----IPPPPPICP 251
PP PP+ P
Sbjct: 465 GLGAMAPPAPPLPP 478
Score = 51.2 bits (121), Expect = 1e-06
Identities = 30/74 (40%), Positives = 32/74 (43%), Gaps = 12/74 (16%)
Query: 185 PKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPP--- 241
P P +S PPPPP P P G L P PPPPP L PP P PP
Sbjct: 427 PPLLPGSSAEPPPPPPPPPLPSVGAKAL-----PTAPPPPPLPGLGAMAPPAPPLPPPLP 481
Query: 242 ----IIPPPPPICP 251
+PPPPP P
Sbjct: 482 GSCEFLPPPPPPLP 495
Score = 50.1 bits (118), Expect = 2e-06
Identities = 33/72 (45%), Positives = 37/72 (51%), Gaps = 17/72 (23%)
Query: 195 PPPPPMPGPRLG----------PGKPGLKFNGPPPPP-PPPPPHLLSC-WLPPFPSGPPI 242
PPPPP P P +G P PGL PP PP PPP P SC +LPP P P
Sbjct: 439 PPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPG--SCEFLPPPPPPLPG 496
Query: 243 I---PPPPPICP 251
+ PPPPP+ P
Sbjct: 497 LGCPPPPPPLLP 508
Score = 42.0 bits (97), Expect = 6e-04
Identities = 21/45 (46%), Positives = 22/45 (48%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSG 239
PPPPP+PG P P L PPPPPPP L PP G
Sbjct: 489 PPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGG 533
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 57.4 bits (137), Expect = 1e-08
Identities = 35/72 (48%), Positives = 38/72 (52%), Gaps = 21/72 (29%)
Query: 195 PPPPPMPG--------PRLGPGKPG-LKFNGPPPPP------PPPPPHLLSCWLPPFPSG 239
PPPPP+PG P L P PG +F PPPPP PPPPP LL P G
Sbjct: 458 PPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLL----PGMGWG 513
Query: 240 PPIIPPPPPICP 251
PP PPPPP+ P
Sbjct: 514 PP--PPPPPLLP 523
Score = 55.1 bits (131), Expect = 7e-08
Identities = 29/74 (39%), Positives = 37/74 (50%), Gaps = 11/74 (14%)
Query: 184 KPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPI- 242
+P++ + PPPPP P P PG PPPPPPPP P + + LP P PP+
Sbjct: 410 QPRALEQQASTPPPPPPP-----PLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLP 464
Query: 243 -----IPPPPPICP 251
PP PP+ P
Sbjct: 465 GLGAMAPPAPPLPP 478
Score = 51.2 bits (121), Expect = 1e-06
Identities = 30/74 (40%), Positives = 32/74 (43%), Gaps = 12/74 (16%)
Query: 185 PKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPP--- 241
P P +S PPPPP P P G L P PPPPP L PP P PP
Sbjct: 427 PPLLPGSSAEPPPPPPPPPLPSVGAKAL-----PTAPPPPPLPGLGAMAPPAPPLPPPLP 481
Query: 242 ----IIPPPPPICP 251
+PPPPP P
Sbjct: 482 GSCEFLPPPPPPLP 495
Score = 50.1 bits (118), Expect = 2e-06
Identities = 33/72 (45%), Positives = 37/72 (51%), Gaps = 17/72 (23%)
Query: 195 PPPPPMPGPRLG----------PGKPGLKFNGPPPPP-PPPPPHLLSC-WLPPFPSGPPI 242
PPPPP P P +G P PGL PP PP PPP P SC +LPP P P
Sbjct: 439 PPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPG--SCEFLPPPPPPLPG 496
Query: 243 I---PPPPPICP 251
+ PPPPP+ P
Sbjct: 497 LGCPPPPPPLLP 508
Score = 42.0 bits (97), Expect = 6e-04
Identities = 21/45 (46%), Positives = 22/45 (48%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSG 239
PPPPP+PG P P L PPPPPPP L PP G
Sbjct: 489 PPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGG 533
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 57.0 bits (136), Expect = 2e-08
Identities = 30/68 (44%), Positives = 33/68 (48%), Gaps = 10/68 (14%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPP---------PPPPPHLLSCWLPPFPSGPPIIPP 245
PPPPP P GP P + G PPPP PPPPP S +PP P + PP
Sbjct: 287 PPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP-PPPNRMYPP 345
Query: 246 PPPICPDS 253
PPP P S
Sbjct: 346 PPPALPSS 353
Score = 54.3 bits (129), Expect = 1e-07
Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 12/83 (14%)
Query: 185 PKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPP--------PPPPPPHLLSCW---- 232
P AP + PPPP P + P P + PPP PPPPPP +L
Sbjct: 314 PSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP 373
Query: 233 LPPFPSGPPIIPPPPPICPDSLD 255
PP P PP PPPPP P D
Sbjct: 374 PPPPPPPPPPGPPPPPGLPSDGD 396
Score = 50.4 bits (119), Expect = 2e-06
Identities = 32/83 (38%), Positives = 35/83 (42%), Gaps = 11/83 (13%)
Query: 176 PGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPP-------PPPHL 228
P ++ P P NS PPPPP G P P PPPPPP PPP
Sbjct: 281 PPSRGGPPPPPPPPHNSG-PPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP 339
Query: 229 LSCWLPP---FPSGPPIIPPPPP 248
+ PP PS P PPPPP
Sbjct: 340 NRMYPPPPPALPSSAPSGPPPPP 362
Score = 46.6 bits (109), Expect = 3e-05
Identities = 38/122 (31%), Positives = 53/122 (43%), Gaps = 19/122 (15%)
Query: 137 NLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPP 196
NL L + ++ E ++ E S+V D E + + ++ ++ P PP
Sbjct: 227 NLDPELKNLFDMCGISEAQLKDRET-SKVIYDFIEKTGGVEAVKNELRRQAPP-----PP 280
Query: 197 PPPMPGPRLGPGKPGLKFNGPPPPP-------PPPPPHL--LSCWLPPFPSGPPI-IPPP 246
PP GP P P N PPPP PPPPP + PP PS P + +PPP
Sbjct: 281 PPSRGGP---PPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPP 337
Query: 247 PP 248
PP
Sbjct: 338 PP 339
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 57.0 bits (136), Expect = 2e-08
Identities = 38/106 (35%), Positives = 47/106 (44%), Gaps = 23/106 (21%)
Query: 171 ENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLS 230
+N SP + D+++ PPP P P + P PPPPPPPPPP+L S
Sbjct: 571 QNQASPCSSGDDMEISDDDRGGS-PPPAPTPPQQPPP---------PPPPPPPPPPYLAS 620
Query: 231 C-----------WLPPFPSG--PPIIPPPPPICPDSLDDADALGSM 263
LPP P G PP PPPPP P D ++L M
Sbjct: 621 LPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPHIYDFVNSLELM 666
Score = 36.6 bits (83), Expect = 0.027
Identities = 50/213 (23%), Positives = 75/213 (35%), Gaps = 32/213 (15%)
Query: 64 GKPKTTPKRKPAKKNKSQKKNTAA--------SLQQWKVGDKCSAIWSEDGCIYPATIAS 115
G+P T P ++ ++ K+Q K+ + Q +K ED A
Sbjct: 935 GRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAV 994
Query: 116 IDFKRETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRS 175
K+ET V G EE + S S + + + + S S+ S +S S
Sbjct: 995 DTTKKETEV----SDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSS 1050
Query: 176 PGNKSDNIKPKS---------APWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPP 226
+ S + + S A S PPP +P P P + + P P P
Sbjct: 1051 SSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPE 1110
Query: 227 HLLSCWLPPFPSGP--------PIIPPPPPICP 251
S P P+GP P+ PP PP P
Sbjct: 1111 QEAS---PARPAGPTEESPPSAPLRPPEPPAGP 1140
Score = 34.7 bits (78), Expect = 0.10
Identities = 27/117 (23%), Positives = 40/117 (34%), Gaps = 20/117 (17%)
Query: 149 ANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLP------------P 196
+++ ++ + + S DE E R S + P+ P + P P
Sbjct: 1045 SSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSP 1104
Query: 197 PPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDS 253
P+P P +P PP P PP P+GPP P P P S
Sbjct: 1105 VTPLPEQEASPARPAGPTEESPPSAPLRPPEP--------PAGPPAPAPRPDERPSS 1153
Score = 34.3 bits (77), Expect = 0.13
Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 20/74 (27%)
Query: 153 EQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGL 212
E+ +E E E + +ES +S S + ++ +S +
Sbjct: 1359 EEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSL--------------------RSHA 1398
Query: 213 KFNGPPPPPPPPPP 226
+ PPPPPPPPPP
Sbjct: 1399 RRRRPPPPPPPPPP 1412
Score = 32.7 bits (73), Expect = 0.39
Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 11/82 (13%)
Query: 169 ESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPH- 227
E+ +R G ++ P SAP L PP P GP +P + + P P PPP
Sbjct: 1112 EASPARPAGPTEES--PPSAP----LRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRR 1165
Query: 228 ----LLSCWLPPFPSGPPIIPP 245
+ + P P PP PP
Sbjct: 1166 KTVSFSAIEVVPAPEPPPATPP 1187
>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
[Homo sapiens]
Length = 355
Score = 56.6 bits (135), Expect = 3e-08
Identities = 51/145 (35%), Positives = 60/145 (41%), Gaps = 26/145 (17%)
Query: 117 DFKRETCVVVY-----TGYGNREEQNLSDLLSPICE-VANNIEQNAQENENESQVSTDES 170
D K CVVV G + + P +A+ I NA Q +T
Sbjct: 182 DSKESACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRM---IQSATPPP 238
Query: 171 ENSRSPGNKSDNIKPKSA--PWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHL 228
+R P + P SA PW F PPP P+P PR +P PPP PPPPPP
Sbjct: 239 PTTRPPPIRPPFSHPLSAHLPWY-FQPPPRPLP-PRPPAAQPR-----PPPSPPPPPPP- 290
Query: 229 LSCWLPPFPSGPPIIPPPPPICPDS 253
PP P PP PPPPP P S
Sbjct: 291 -----PPSPLPPP--PPPPPPTPSS 308
Score = 37.4 bits (85), Expect = 0.016
Identities = 26/65 (40%), Positives = 27/65 (41%), Gaps = 11/65 (16%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGP---PPPPPPPPPHLLSCWLPPF--PSGPPIIPPPPPI 249
PPP P P P L + P PPP P PP PP P PP PPPPP
Sbjct: 237 PPPTTRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPR------PPAAQPRPPPSPPPPPPP 290
Query: 250 CPDSL 254
P L
Sbjct: 291 PPSPL 295
Score = 35.4 bits (80), Expect = 0.060
Identities = 18/40 (45%), Positives = 19/40 (47%), Gaps = 8/40 (20%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLP 234
P PPP P P P PPPPPPPPP + LP
Sbjct: 282 PSPPPPPPPPPSP--------LPPPPPPPPPTPSSTTKLP 313
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 55.5 bits (132), Expect = 6e-08
Identities = 34/89 (38%), Positives = 37/89 (41%), Gaps = 12/89 (13%)
Query: 185 PKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLL------SCWLPPFPS 238
P P SF PP P P P P P N PPPPP PP H + LPP
Sbjct: 486 PVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASY 545
Query: 239 GPPIIPP------PPPICPDSLDDADALG 261
PP +PP PPPI P + LG
Sbjct: 546 PPPAVPPGGQPPVPPPIPPPGMPPVGGLG 574
Score = 47.0 bits (110), Expect = 2e-05
Identities = 26/58 (44%), Positives = 30/58 (51%), Gaps = 8/58 (13%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPP--PPPPPHLLSCWLPPFPSGPP--IIPPPPP 248
PPPPP+P P P + PPP P PPPPP + PP P PP +PP PP
Sbjct: 482 PPPPPVPPPPASFPPPAI----PPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPP 535
Score = 41.6 bits (96), Expect = 8e-04
Identities = 23/52 (44%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 197 PPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPP 248
PP P P P + PPPPP PPPP S P P P PPPPP
Sbjct: 462 PPAYGPPAHLPYHPHVYPPNPPPPPVPPPP--ASFPPPAIPPPTPGYPPPPP 511
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 15/65 (23%)
Query: 196 PPPPMP-GPRLGPGKPGLKFNGPPPPPPPPP--------PHLLSCWLPPFPSGPPIIPPP 246
PP +P P + P P PPPP PPPP P + PP P+ P PPP
Sbjct: 467 PPAHLPYHPHVYPPNP------PPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520
Query: 247 PPICP 251
PP P
Sbjct: 521 PPRLP 525
Score = 30.8 bits (68), Expect = 1.5
Identities = 27/101 (26%), Positives = 35/101 (34%), Gaps = 4/101 (3%)
Query: 154 QNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLK 213
Q + + +Q S SP + N PPPP P++ P L
Sbjct: 308 QQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKI-PKIETTHPPLP 366
Query: 214 FNGPPPPPPPPPPHLLSCWLPPFP---SGPPIIPPPPPICP 251
PPP PP L PP P + P + PPP P
Sbjct: 367 PAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHP 407
Score = 30.8 bits (68), Expect = 1.5
Identities = 26/84 (30%), Positives = 30/84 (35%), Gaps = 31/84 (36%)
Query: 195 PPPPP-------------MPGPRLGPGKPGLKFNGP----------PPPPPPPPPHLLSC 231
PPPPP M G + +K GP PP P PH+
Sbjct: 421 PPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHV--- 477
Query: 232 WLPPFPSGPPIIPP----PPPICP 251
PP P PP+ PP PPP P
Sbjct: 478 -YPPNPPPPPVPPPPASFPPPAIP 500
Score = 28.9 bits (63), Expect = 5.7
Identities = 27/107 (25%), Positives = 37/107 (34%), Gaps = 9/107 (8%)
Query: 158 ENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGP 217
+ SQ S + P + +P P P P R P +
Sbjct: 289 QQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAA 348
Query: 218 PPPPPPPPPHLLSCWLPPFPSGPPIIPPP---PPICPDSLDDADALG 261
PPPP P + PP PP PPP PP+ +L +A+ G
Sbjct: 349 EPPPPKIPK--IETTHPPL---PPAHPPPDRKPPLAA-ALGEAEPPG 389
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 55.1 bits (131), Expect = 7e-08
Identities = 28/56 (50%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 196 PPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICP 251
PPPP+PG PG P + GPPPPP P PP PP P GPP+ PPP P
Sbjct: 296 PPPPVPGYGPPPGPPPPQ-QGPPPPPGPFPPR------PPGPLGPPLTLAPPPHLP 344
Score = 47.4 bits (111), Expect = 2e-05
Identities = 31/71 (43%), Positives = 32/71 (45%), Gaps = 7/71 (9%)
Query: 185 PKSAPWNSFLPPP---PPMPGPRLGPGK--PGLKFNGPP--PPPPPPPPHLLSCWLPPFP 237
P P LPPP PP G R P PG F PP P PP PPP + PP P
Sbjct: 250 PGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGP 309
Query: 238 SGPPIIPPPPP 248
P PPPPP
Sbjct: 310 PPPQQGPPPPP 320
Score = 45.4 bits (106), Expect = 6e-05
Identities = 28/60 (46%), Positives = 33/60 (55%), Gaps = 9/60 (15%)
Query: 196 PPPPMPGPRLGPGKPGLKFNGPP-PPPPPPPPHLLSCWLPPFPSGPP---IIPPPPPICP 251
PPPP P + P +P L GPP PP PPPP + LPP +GPP PPPP + P
Sbjct: 226 PPPPFPAGQTPP-RPPLGPPGPPGPPGPPPPGQV----LPPPLAGPPNRGDRPPPPVLFP 280
Score = 45.4 bits (106), Expect = 6e-05
Identities = 29/74 (39%), Positives = 32/74 (43%), Gaps = 20/74 (27%)
Query: 195 PPPPPMPGPRLGPG--------KPGLKFNGPPPPPPPPPPHLLSCWLPP-----FPS--- 238
PPPPP P P PG P GPPP PPP PH+ + PP P+
Sbjct: 316 PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDS 375
Query: 239 -GPPIIPP---PPP 248
GPP P PPP
Sbjct: 376 RGPPPTDPYGRPPP 389
Score = 39.3 bits (90), Expect = 0.004
Identities = 36/95 (37%), Positives = 40/95 (42%), Gaps = 29/95 (30%)
Query: 174 RSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPP----PPP------ 223
R PG P P PP PP+ GP PG P GPPPP PPP
Sbjct: 216 RFPGPAGPGGPPPPFPAGQ-TPPRPPL-GPPGPPGPP-----GPPPPGQVLPPPLAGPPN 268
Query: 224 ----PPPHLLSCWLPPFPSG-PPIIP----PPPPI 249
PPP +L P P G PP+ P PPPP+
Sbjct: 269 RGDRPPPPVL---FPGQPFGQPPLGPLPPGPPPPV 300
Score = 38.1 bits (87), Expect = 0.009
Identities = 35/112 (31%), Positives = 43/112 (38%), Gaps = 19/112 (16%)
Query: 153 EQNAQENENESQVSTDESENSRS-----PGNKSDNIKPKSAPWNSFLPPPPP----MPGP 203
+Q + E +S+ +T + S PG S P+ P P PGP
Sbjct: 161 KQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGP 220
Query: 204 RLGPGKPGLKFN-GPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSL 254
GPG P F G PP PP PP P GPP PPP + P L
Sbjct: 221 A-GPGGPPPPFPAGQTPPRPPLG--------PPGPPGPPGPPPPGQVLPPPL 263
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 54.7 bits (130), Expect = 1e-07
Identities = 38/101 (37%), Positives = 46/101 (45%), Gaps = 25/101 (24%)
Query: 169 ESENSRSPGNKSDNIKPKSAPWN-----------------SFLPPPPPMPGPRLG--PG- 208
+S +S SP DN+ P A ++ S + P P P P LG PG
Sbjct: 253 DSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGP 312
Query: 209 KPGLKFNGPPPPPPPPPPHLLSCWLPPFP--SGPPIIPPPP 247
KPG PPP PPPPPP ++ PP P G P PPPP
Sbjct: 313 KPGF---APPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPP 350
Score = 54.3 bits (129), Expect = 1e-07
Identities = 39/94 (41%), Positives = 41/94 (43%), Gaps = 29/94 (30%)
Query: 184 KPKSAPWNSFLPPPPPM-----PGPRLGPGKPGLK-------------FNGPPPPPPPP- 224
KP AP + PPPPPM P P +G G PG F PPPPPPPP
Sbjct: 313 KPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA 372
Query: 225 ------PPHLLSCWL----PPFPSGPPIIPPPPP 248
PP LS PP P PP PPPPP
Sbjct: 373 ADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP 406
Score = 52.4 bits (124), Expect = 5e-07
Identities = 33/79 (41%), Positives = 33/79 (41%), Gaps = 9/79 (11%)
Query: 175 SPGNKSDNIKPKSAPWNSFLPPPPPMPGPR-----LGPGKPGLKFNGPPPPPPPPPPHLL 229
SPG P P F PPPP P P L P G PPPPPPPPP
Sbjct: 343 SPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPP-- 400
Query: 230 SCWLPPF--PSGPPIIPPP 246
PPF G P IPPP
Sbjct: 401 GPPPPPFTGADGQPAIPPP 419
Score = 33.5 bits (75), Expect = 0.23
Identities = 26/83 (31%), Positives = 27/83 (32%), Gaps = 33/83 (39%)
Query: 196 PPPPMPGPRLGPGKPGLKFNGPPPPP---------------------------PPPPPHL 228
PPPP P + N PPPP PPP P L
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
Query: 229 LSCWLPPFPS---GPPIIPPPPP 248
S PP P PP PPPPP
Sbjct: 307 GS---PPGPKPGFAPPPAPPPPP 326
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 54.7 bits (130), Expect = 1e-07
Identities = 33/86 (38%), Positives = 36/86 (41%), Gaps = 11/86 (12%)
Query: 169 ESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMP---GPRLGPGKPGLKFNGPPPPPPPPP 225
E+ + P + S P P LPP PP P GP P PPP PPPPP
Sbjct: 1942 EAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPP 2001
Query: 226 PHLLSCWLPPFPSGPPIIPPPPPICP 251
PP P PP PPPPP P
Sbjct: 2002 --------PPPPPPPPPPPPPPPSAP 2019
Score = 43.9 bits (102), Expect = 2e-04
Identities = 33/84 (39%), Positives = 37/84 (44%), Gaps = 12/84 (14%)
Query: 187 SAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHL---LSCWLPPFPS---GP 240
S P + P PPP P P P P PPPPPP PP + +S LP FPS P
Sbjct: 1987 STPLQAPPPTPPPPPPPPPPPPPP------PPPPPPSAPPQVQLPVSLDLPLFPSIMMQP 2040
Query: 241 PIIPPPPPICPDSLDDADALGSML 264
P PP L DAL + L
Sbjct: 2041 VQHPALPPQLALQLPQMDALSADL 2064
Score = 37.0 bits (84), Expect = 0.021
Identities = 23/58 (39%), Positives = 26/58 (44%), Gaps = 4/58 (6%)
Query: 173 SRSPG--NKSDNIKPKSAPWNSFLPPPPPMPGPRLG--PGKPGLKFNGPPPPPPPPPP 226
S PG S+ + P A F P L P KP L+ PPPPPPPPPP
Sbjct: 3071 SSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPP 3128
Score = 33.1 bits (74), Expect = 0.30
Identities = 18/44 (40%), Positives = 18/44 (40%), Gaps = 17/44 (38%)
Query: 187 SAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLS 230
SAP L PPP PPPPPPPPP LS
Sbjct: 3107 SAPTKPLLQTPPP-----------------PPPPPPPPPSSSLS 3133
Score = 30.0 bits (66), Expect = 2.5
Identities = 28/81 (34%), Positives = 29/81 (35%), Gaps = 12/81 (14%)
Query: 185 PKSAPWNSFLPPP--PPMPGPRLGPG---------KPGLKFNG-PPPPPPPPPPHLLSCW 232
P + P LPP P M GP PG PG G P P L S
Sbjct: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAP 3109
Query: 233 LPPFPSGPPIIPPPPPICPDS 253
P PP PPPPP P S
Sbjct: 3110 TKPLLQTPPPPPPPPPPPPSS 3130
Score = 29.6 bits (65), Expect = 3.3
Identities = 22/69 (31%), Positives = 24/69 (34%), Gaps = 22/69 (31%)
Query: 191 NSFLPPPPPMPG-PRLGPGKPGLKFNGPPPPP----PPPPPHLLSCWLPPFPSGPPIIPP 245
N+ PP M G P P L + P P PPPPP PP
Sbjct: 3081 NTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPP-----------------PP 3123
Query: 246 PPPICPDSL 254
PPP SL
Sbjct: 3124 PPPPPSSSL 3132
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 54.3 bits (129), Expect = 1e-07
Identities = 67/245 (27%), Positives = 92/245 (37%), Gaps = 63/245 (25%)
Query: 47 VASFKHALKNGD---------ICETSGKPKTTPKRKPAKKNKSQKKNTAASLQQ-----W 92
+ASF LK+G + PK+ P PA+ + Q T A +
Sbjct: 1282 MASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAF 1341
Query: 93 KVGDKCSAIWSED---GCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPICEVA 149
+G A SE GC P + KR NL L S +
Sbjct: 1342 GLGGALEAAESEGLGLGCPSPCKRLDEELKR----------------NLETLPSFSSDEE 1385
Query: 150 NNIEQNAQENEN-ESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPG-PRLG- 206
+++ +N E+ S +S + P + S P AP + +P PPP+PG P
Sbjct: 1386 DSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAP-AAAVPGPPPLPGLPSANS 1444
Query: 207 ---PGKPGLKFNGPP-----------PPPPPPPPHLLSCWLPPFPSGPPII------PPP 246
P P L+ PP PPPPPPPP P PS PP++ PPP
Sbjct: 1445 NGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQ------PALPSPPPLVAPTPSSPPP 1498
Query: 247 PPICP 251
PP+ P
Sbjct: 1499 PPLPP 1503
Score = 54.3 bits (129), Expect = 1e-07
Identities = 41/142 (28%), Positives = 55/142 (38%), Gaps = 37/142 (26%)
Query: 147 EVANNIEQ--NAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPM---- 200
E+ N+E + +E +S + + S S + + P + P ++ P PP+
Sbjct: 1369 ELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAA 1428
Query: 201 --PGPRLGPGKPGLKFNG------------------------PPPPPPPPPPHL-----L 229
PGP PG P NG PPPPPPPP P L L
Sbjct: 1429 AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPL 1488
Query: 230 SCWLPPFPSGPPIIPPPPPICP 251
P P PP+ PPPPP P
Sbjct: 1489 VAPTPSSPPPPPLPPPPPPAMP 1510
Score = 52.4 bits (124), Expect = 5e-07
Identities = 30/60 (50%), Positives = 31/60 (51%), Gaps = 12/60 (20%)
Query: 195 PPPPPMPGPRLGPGKPGLKF---NGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICP 251
PPPPP P P L P P L + PPPPP PPPP P PS PP PPPP P
Sbjct: 1472 PPPPPPPQPAL-PSPPPLVAPTPSSPPPPPLPPPPP------PAMPSPPP--PPPPAAAP 1522
Score = 42.0 bits (97), Expect = 6e-04
Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 8/72 (11%)
Query: 185 PKSAPWNSFLPPPPPMPGPR-LGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPII 243
P P LP PPP+ P P P L PP P PPPP PP + P
Sbjct: 1473 PPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPP-------PPPAAAPLAA 1525
Query: 244 PPPPPICPDSLD 255
PP P P D
Sbjct: 1526 PPEEPAAPSPED 1537
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/97 (32%), Positives = 37/97 (38%), Gaps = 32/97 (32%)
Query: 194 LPPPPPM---------PGPRLGPGKPGLKF---------NGPPPPPPPPPP--------H 227
LPPPPP P P K G+ PPPPPPPPPP H
Sbjct: 794 LPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAH 853
Query: 228 LLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSML 264
L S L P P + P +SLD A+ +L
Sbjct: 854 LRSHGLEPAAPSPRLRP------EESLDPPGAMQELL 884
Score = 38.1 bits (87), Expect = 0.009
Identities = 26/71 (36%), Positives = 28/71 (39%), Gaps = 16/71 (22%)
Query: 185 PKSAPWNSFLPPPP--PMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPI 242
P AP S PPPP P P P + P PPPPPPP PP P
Sbjct: 1487 PLVAPTPSSPPPPPLPPPPPPAM------------PSPPPPPPPAAAPLAAPPEEPAAP- 1533
Query: 243 IPPPPPICPDS 253
P P PD+
Sbjct: 1534 -SPEDPELPDT 1543
Score = 37.4 bits (85), Expect = 0.016
Identities = 29/80 (36%), Positives = 30/80 (37%), Gaps = 23/80 (28%)
Query: 195 PPPPPMPGPRLGPGKPGL--KFNGPPPPP--PPPPPHLLSCWLPPFPS------------ 238
PPPPP P GL + GP P PPPPP LL L PS
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
Query: 239 -------GPPIIPPPPPICP 251
G P PPPPP P
Sbjct: 824 LEPATRDGAPQPPPPPPPPP 843
Score = 34.3 bits (77), Expect = 0.13
Identities = 20/46 (43%), Positives = 21/46 (45%), Gaps = 17/46 (36%)
Query: 198 PPMPGPRLGPGKP------------GLKFNGP-----PPPPPPPPP 226
P PG L P KP GL +GP PPPPPPPPP
Sbjct: 1003 PETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPP 1048
Score = 33.1 bits (74), Expect = 0.30
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 14/79 (17%)
Query: 178 NKSDNIKPKSA-PWNSFLPPPPPMPGPRLGPGKPGLKFNG--------PPPPPPPPPPHL 228
NK D ++ + PW+ PP+P R G K + G P PPP P P
Sbjct: 1654 NKKDYVRVCARKPWHR-----PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEK 1708
Query: 229 LSCWLPPFPSGPPIIPPPP 247
+ PP + +P PP
Sbjct: 1709 TTSEKPPEQTPETAMPEPP 1727
Score = 31.6 bits (70), Expect = 0.87
Identities = 23/68 (33%), Positives = 24/68 (35%), Gaps = 14/68 (20%)
Query: 195 PPPPPMPGPRLGPGKPGLKFNGPPPPP-----PPPPPHLLSC---------WLPPFPSGP 240
PPP P GP PG P P P PP L S P + P
Sbjct: 980 PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAP 1039
Query: 241 PIIPPPPP 248
P PPPPP
Sbjct: 1040 PPPPPPPP 1047
Score = 30.8 bits (68), Expect = 1.5
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Query: 195 PPPPPMPGPRLGPG-KPGLKFNGPPPPPPPPPPHLLSCWL 233
PPPP PR K + PPPPPPP H L +L
Sbjct: 275 PPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYL 314
Score = 30.0 bits (66), Expect = 2.5
Identities = 24/78 (30%), Positives = 29/78 (37%), Gaps = 27/78 (34%)
Query: 196 PPPPMPGPRLGPGKPGL-------------------KFNGPPPPPPPPPPHL------LS 230
PP P P PR P + L F+G P PPPP L +
Sbjct: 231 PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIK 290
Query: 231 CWLPPFPSGPPIIPPPPP 248
+ P + PP PPPPP
Sbjct: 291 HYQRPASAQPP--PPPPP 306
Score = 28.1 bits (61), Expect = 9.6
Identities = 21/52 (40%), Positives = 23/52 (44%), Gaps = 5/52 (9%)
Query: 182 NIKPKSAPW-NSFLPPPPPMPGPRLGPGKPGLKFNGP----PPPPPPPPPHL 228
++KP AP S L G LGP G P PP PPPPP HL
Sbjct: 190 HLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHL 241
Score = 28.1 bits (61), Expect = 9.6
Identities = 11/20 (55%), Positives = 14/20 (70%), Gaps = 2/20 (10%)
Query: 214 FNGPPPPPP--PPPPHLLSC 231
++G PP PP PPPP L +C
Sbjct: 475 YSGGPPQPPSGPPPPGLATC 494
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/112 (37%), Positives = 51/112 (45%), Gaps = 25/112 (22%)
Query: 147 EVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLG 206
E +E Q+ ++QV S +S PG P +AP + PPPP P P L
Sbjct: 523 EKIKELEAEIQQLRTQAQVL---SSSSGIPG-------PPAAPPLPGVGPPPPPPAPPLP 572
Query: 207 PGKPGLKFNGPPPP-------PPPPPPHLLSCWLPPFPSGPPI--IPPPPPI 249
G P PPPP PPPPPP LL PP PP+ +PPPP I
Sbjct: 573 GGAP---LPPPPPPLPGMMGIPPPPPPPLLFGGPPP---PPPLGGVPPPPGI 618
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/112 (37%), Positives = 51/112 (45%), Gaps = 25/112 (22%)
Query: 147 EVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLG 206
E +E Q+ ++QV S +S PG P +AP + PPPP P P L
Sbjct: 523 EKIKELEAEIQQLRTQAQVL---SSSSGIPG-------PPAAPPLPGVGPPPPPPAPPLP 572
Query: 207 PGKPGLKFNGPPPP-------PPPPPPHLLSCWLPPFPSGPPI--IPPPPPI 249
G P PPPP PPPPPP LL PP PP+ +PPPP I
Sbjct: 573 GGAP---LPPPPPPLPGMMGIPPPPPPPLLFGGPPP---PPPLGGVPPPPGI 618
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,644,047
Number of Sequences: 37866
Number of extensions: 1521750
Number of successful extensions: 31977
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 883
Number of HSP's successfully gapped in prelim test: 840
Number of HSP's that attempted gapping in prelim test: 9889
Number of HSP's gapped (non-prelim): 10359
length of query: 294
length of database: 18,247,518
effective HSP length: 101
effective length of query: 193
effective length of database: 14,423,052
effective search space: 2783649036
effective search space used: 2783649036
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.