Guide to the Human Genome
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Name: SMN2 Sequence: fasta or formatted (282aa) NCBI GI: 13259527
Description:

survival of motor neuron 2, centromeric isoform a

Referenced in:

Capping and Splicing

Other entries for this name:
alt prot [294aa] survival of motor neuron 2, centromeric isoform d
alt prot [262aa] survival of motor neuron 2, centromeric isoform b
alt prot [250aa] survival of motor neuron 2, centromeric isoform c
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.4         18           2
 C cysteine            2.5          7           1
 D aspartate           6.4         18           2
 E glutamate           5.3         15           2
 F phenylalanine       2.1          6           1
 G glycine             8.2         23           3
 H histidine           1.1          3           1
 I isoleucine          5.0         14           2
 K lysine              7.4         21           2
 L leucine             6.0         17           2
 M methionine          2.5          7           1
 N asparagine          5.3         15           2
 P proline            13.8         39          10
 Q glutamine           3.2          9           2
 R arginine            2.5          7           2
 S serine             10.3         29           2
 T threonine           3.9         11           2
 V valine              3.2          9           3
 W tryptophan          2.1          6           1
 Y tyrosine            2.8          8           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   survival of motor neuron 2, centromeric isoform a [H... 
SMN2                  0.988   survival of motor neuron 2, centromeric isoform d [H...
SMN1                  0.988   survival of motor neuron 1, telomeric isoform d [Homo...
SMN2                  0.834   survival of motor neuron 2, centromeric isoform c [H...
SMN2                  0.821   survival of motor neuron 2, centromeric isoform b [H...
SMN1                  0.821   survival of motor neuron 1, telomeric isoform b [Hom...
FMN1                  0.068   formin 1 
FMNL1                 0.064   formin-like 1 
DIAPH1                0.062   diaphanous 1 isoform 2 
DIAPH1                0.062   diaphanous 1 isoform 1 
SETD1B                0.061   SET domain containing 1B 
ZC3H4                 0.061   zinc finger CCCH-type containing 4 
SMNDC1                0.061   survival motor neuron domain containing 1 
FMN2                  0.061   formin 2 
ENAH                  0.059   enabled homolog isoform a 
ENAH                  0.059   enabled homolog isoform b 
DIAPH3                0.057   diaphanous homolog 3 isoform b 
DIAPH3                0.057   diaphanous homolog 3 isoform a 
INF2                  0.055   inverted formin 2 isoform 2 
INF2                  0.055   inverted formin 2 isoform 1 
WASL                  0.055   Wiskott-Aldrich syndrome gene-like protein 
SETD1A                0.055   SET domain containing 1A 
LOC645529             0.055   PREDICTED: similar to Putative acrosin-like proteas...
CCNK                  0.052   cyclin K isoform 1 
CPSF6                 0.052   cleavage and polyadenylation specific factor 6, 68 ...
WASF2                 0.052   WAS protein family, member 2 
ZFHX4                 0.052   zinc finger homeodomain 4 
PRR12                 0.050   proline rich 12 
DIAPH2                0.050   diaphanous 2 isoform 12C 
DIAPH2                0.050   diaphanous 2 isoform 156 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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