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Search of human proteins with 4507035
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507035 solute carrier family 5 (sodium iodide symporter),
member 5 [Homo sapiens]
(643 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507035 solute carrier family 5 (sodium iodide symporter), me... 1276 0.0
gi|167466278 solute carrier family 5 (iodide transporter), membe... 576 e-164
gi|157671931 solute carrier family 5 (sodium/glucose cotransport... 537 e-152
gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr... 444 e-124
gi|17941285 solute carrier family 5 (sodium/glucose cotransporte... 117 3e-26
gi|4507033 solute carrier family 5 (sodium/glucose cotransporter... 114 4e-25
gi|14140236 solute carrier family 5 (low affinity glucose cotran... 112 1e-24
gi|4507031 solute carrier family 5 (sodium/glucose cotransporter... 109 9e-24
gi|109659836 solute carrier family 5 (sodium/glucose cotransport... 107 3e-23
gi|110835708 solute carrier family 5 (inositol transporters), me... 102 1e-21
gi|109659839 solute carrier family 5 (sodium/glucose cotransport... 101 2e-21
gi|206597483 solute carrier family 5 (sodium/glucose cotransport... 100 3e-21
gi|206597487 solute carrier family 5 (sodium/glucose cotransport... 91 3e-18
gi|11141885 solute carrier family 5 (choline transporter), membe... 77 5e-14
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 34 0.48
gi|239745235 PREDICTED: hypothetical protein [Homo sapiens] 33 0.62
gi|26024197 diacylglycerol O-acyltransferase 2 [Homo sapiens] 31 4.0
gi|54019430 olfactory receptor, family 6, subfamily C, member 75... 31 4.0
gi|118582267 equilibrative nucleoside transporter 1 [Homo sapiens] 30 6.9
gi|118582265 equilibrative nucleoside transporter 1 [Homo sapiens] 30 6.9
gi|118582262 equilibrative nucleoside transporter 1 [Homo sapiens] 30 6.9
gi|118582260 equilibrative nucleoside transporter 1 [Homo sapiens] 30 6.9
gi|4826716 equilibrative nucleoside transporter 1 [Homo sapiens] 30 6.9
gi|50080213 olfactory receptor, family 6, subfamily C, member 3 ... 30 6.9
gi|13376816 CXXC finger 4 [Homo sapiens] 30 9.0
gi|139394648 DNA polymerase theta [Homo sapiens] 30 9.0
gi|55953085 G protein-coupled receptor 120 [Homo sapiens] 30 9.0
>gi|4507035 solute carrier family 5 (sodium iodide symporter),
member 5 [Homo sapiens]
Length = 643
Score = 1276 bits (3301), Expect = 0.0
Identities = 643/643 (100%), Positives = 643/643 (100%)
Query: 1 MEAVETGERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVG 60
MEAVETGERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVG
Sbjct: 1 MEAVETGERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVG 60
Query: 61 LSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEY 120
LSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEY
Sbjct: 61 LSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEY 120
Query: 121 LEMRFSRAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTA 180
LEMRFSRAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTA
Sbjct: 121 LEMRFSRAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTA 180
Query: 181 VGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRS 240
VGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRS
Sbjct: 181 VGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRS 240
Query: 241 RYTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCG 300
RYTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCG
Sbjct: 241 RYTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCG 300
Query: 301 IVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSIN 360
IVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSIN
Sbjct: 301 IVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSIN 360
Query: 361 AMAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVM 420
AMAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVM
Sbjct: 361 AMAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVM 420
Query: 421 GVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSA 480
GVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSA
Sbjct: 421 GVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSA 480
Query: 481 ARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTV 540
ARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTV
Sbjct: 481 ARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTV 540
Query: 541 LCGALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTGNKK 600
LCGALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTGNKK
Sbjct: 541 LCGALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTGNKK 600
Query: 601 PPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL 643
PPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL
Sbjct: 601 PPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL 643
>gi|167466278 solute carrier family 5 (iodide transporter), member 8
[Homo sapiens]
Length = 610
Score = 576 bits (1485), Expect = e-164
Identities = 283/546 (51%), Positives = 392/546 (71%), Gaps = 5/546 (0%)
Query: 11 TFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSA 70
TF WDY VFA ML++S IG++ A GGQ++++DF GGRR+ A+PV LSL+ASFMSA
Sbjct: 9 TFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSA 68
Query: 71 VQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVR 130
V VLG PSE YR+G F V++A +F+PVFY+LG+TSTYEYLE+RF++ VR
Sbjct: 69 VTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFNKCVR 128
Query: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190
LCGT+ +IV T+LYTGIVIYAPAL LNQVTG D+W ++++TG++CTFY +GG+KAV+WT
Sbjct: 129 LCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWT 188
Query: 191 DVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVG 250
DVFQV +M++GF V+ + V++ GG +L A + R+N +FNP+P R+TFWT ++G
Sbjct: 189 DVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFWTIIIG 248
Query: 251 GTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTDC 310
GT W S+YGVNQ+QVQRY++C++ QAKL+L IN VGL+ I++ + CG+ ++ Y DC
Sbjct: 249 GTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYSRYHDC 308
Query: 311 DPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDL 370
DP ++SAPDQ MP LVLDI +D PG+PGLF+ACAYSGTLST S+SINA+AAVTVEDL
Sbjct: 309 DPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVEDL 368
Query: 371 IKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGA 430
IKP RSL+ R L IS+G+S++YG+ C+ +AAL+SL+ G +LQ + +V G++ GPL+G
Sbjct: 369 IKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLM-GALLQAALSVFGMVGGPLMGL 427
Query: 431 FILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALSVNA 490
F LG+ +P N+ G L GL AG A+SLWV +GA +YPP + L C + + N
Sbjct: 428 FALGILVPFANSIGALVGLMAGFAISLWVGIGAQIYPPLPERTLPLHLDIQGCNS-TYNE 486
Query: 491 SGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLT 550
+ L+ +P S + R L D++Y++SYLY+ +GTL T+L G L+S T
Sbjct: 487 TNLMTTTEMPFTTS---VFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVGILVSLST 543
Query: 551 GPTKRS 556
G K++
Sbjct: 544 GGRKQN 549
>gi|157671931 solute carrier family 5 (sodium/glucose
cotransporter), member 12 [Homo sapiens]
Length = 618
Score = 537 bits (1383), Expect = e-152
Identities = 269/556 (48%), Positives = 372/556 (66%), Gaps = 18/556 (3%)
Query: 8 ERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASF 67
E F WDY VFA + +S+GIG++ + + ++ +F GGR+++ PVGLSL+ASF
Sbjct: 2 EVKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASF 61
Query: 68 MSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSR 127
MSAV VLG PSE YR+G FL + L +LT+ LF+PVFYR G+TSTYEYL++RF++
Sbjct: 62 MSAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNK 121
Query: 128 AVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAV 187
VR T+ YIV T+LYTG+V+YAPAL LNQVTG D+W S+ +TGI+CTFY +GG+KAV
Sbjct: 122 PVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAV 181
Query: 188 VWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTF 247
VWTD FQ+VVM+ GF VL +G GG VL + N SR+++ DF+ DP R+TFWT
Sbjct: 182 VWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTI 241
Query: 248 VVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFY 307
VGGT WL +YGVNQ+ +QR ++C+TEK AKLAL N +GL++I+ A G++M+ +
Sbjct: 242 TVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHF 301
Query: 308 TDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTV 367
DCDP G ISAPDQ MP V++IF +PG+PGLF+ACA+SGTLST ++SINA+A VT
Sbjct: 302 KDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTF 361
Query: 368 EDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPL 427
ED +K L+ + ISKGL L++G C ++A +S++ GGV+Q S ++ G+ GP+
Sbjct: 362 EDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVM-GGVVQASLSIHGMCGGPM 420
Query: 428 LGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALS 487
LG F LG+ P N G L GL G+ LS WVA+GA +YP LP S +C+ +
Sbjct: 421 LGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSN 480
Query: 488 VNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALIS 547
V A+G P +L +SRP +AD++Y+ISYLYY A+G L ++ G +IS
Sbjct: 481 VTATG---PPVL--------------SSRPGIADTWYSISYLYYSAVGCLGCIVAGVIIS 523
Query: 548 CLTGPTKRSTLAPGLL 563
+TG + + P L+
Sbjct: 524 LITGRQRGEDIQPLLI 539
>gi|10863879 solute carrier family 5 (sodium-dependent vitamin
transporter), member 6 [Homo sapiens]
Length = 635
Score = 444 bits (1141), Expect = e-124
Identities = 237/562 (42%), Positives = 348/562 (61%), Gaps = 29/562 (5%)
Query: 11 TFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSA 70
TF DY VF L+L++S IGL+ G+ + + R++ LPV LSL A+F SA
Sbjct: 23 TFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSA 82
Query: 71 VQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVR 130
V +LGVPSE YR+G ++ ++ L ++ A +F+PVFYRL LTS YEYLE+RF++ VR
Sbjct: 83 VAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKTVR 142
Query: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190
+CGT+ +I ++Y G+V+YAP+L LN VTG D+W S+L+ GI+CT YTA+GG+KAV+WT
Sbjct: 143 VCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWT 202
Query: 191 DVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVG 250
DVFQ +VM G V+ G VGG +V +A H RI+ + +PDP R+TFWT G
Sbjct: 203 DVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLAFG 262
Query: 251 GTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACC--GIVMFVFYT 308
G + LS+YGVNQAQVQRY++ RTEK A L+ V F VS C G+VMF +Y
Sbjct: 263 GVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCY--AVFPFQQVSLCVGCLIGLVMFAYYQ 320
Query: 309 DCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVE 368
+ + +APDQ++ V+D+ + LPG+PGLF+AC +SG+LST S++ N++A VT+E
Sbjct: 321 EYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTME 380
Query: 369 DLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLL 428
DLI+P + + +++S+GL+ YG CL +A +SS + G VLQ + ++ G++ GPLL
Sbjct: 381 DLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQM-GPVLQAAISIFGMVGGPLL 439
Query: 429 GAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATL------YPPSEQTMRVLPSSAAR 482
G F LGMF P N PG + GL AGL ++ W+ +G+ + PPS PS+ +
Sbjct: 440 GLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPS-------PSNGS- 491
Query: 483 CVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLC 542
+L N + L+P S+P FY++SYL+Y A + T ++
Sbjct: 492 SFSLPTNLTVATVTTLMPLT----------TFSKPTGLQRFYSLSYLWYSAHNSTTVIVV 541
Query: 543 GALISCLTGPTKRSTLAPGLLW 564
G ++S LTG + +L P ++
Sbjct: 542 GLIVSLLTGRMRGRSLNPATIY 563
>gi|17941285 solute carrier family 5 (sodium/glucose cotransporter),
member 11 [Homo sapiens]
Length = 675
Score = 117 bits (294), Expect = 3e-26
Identities = 114/472 (24%), Positives = 204/472 (43%), Gaps = 37/472 (7%)
Query: 16 DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75
D V L L +GLW + + + + +F G + PVG SL AS + + +G
Sbjct: 28 DIAVLVLYFLFVLAVGLW-STVKTKRDTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIG 86
Query: 76 VPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS--RAVRLCG 133
+ G+ L L + ++ A +F+P++ +T+ EYL RF R +
Sbjct: 87 LAGSGAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYLRKRFGGIRIPIILA 146
Query: 134 TLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDVF 193
L + + +YA A+ + Q LD++ +++ I YT GG+ AV++TD
Sbjct: 147 VLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYTDAL 206
Query: 194 QVVVMLSGFWVVLARGVMLVGG-----PRQVLTLAQNHS--------RINLMDFNPDPRS 240
Q ++ML G ++ VGG + L LA N S R + DP +
Sbjct: 207 QTLIMLIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLT 266
Query: 241 RYTFWTFVV-GGTLVWLSMYGVNQAQVQRYVACRTEKQAK----LALLINQVGLFLIVSS 295
W V+ G ++ L + +Q VQR +A + AK +A + + LF++V
Sbjct: 267 SDLPWPGVLFGMSIPSLWYWCTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIMVFP 326
Query: 296 AACCGIVMFVFYTD----CDPLLLGRI-----SAPDQYMPLLVLDIFEDLPGVPGLFLAC 346
G+V + + D DP + +I D P LVL++ G+ GL +A
Sbjct: 327 ----GMVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLP--TGLRGLMMAV 380
Query: 347 AYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISK-GLSLIYGSACLTVAALS 405
+ +S+ ++ N+ + + DL + ++L+I+ + + L+ + L + +
Sbjct: 381 MVAALMSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGRVFVLLLVLVSILWIPVVQ 440
Query: 406 SLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSL 457
+ GG + ++ + P+ FI+G F N G GL +GL L L
Sbjct: 441 ASQGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKGAFWGLISGLLLGL 492
>gi|4507033 solute carrier family 5 (sodium/glucose cotransporter),
member 2 [Homo sapiens]
Length = 672
Score = 114 bits (284), Expect = 4e-25
Identities = 122/503 (24%), Positives = 212/503 (42%), Gaps = 55/503 (10%)
Query: 2 EAVETGERPTFGAW--------DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRR 53
E E G P GA D V A L+ G+GLW + R + + +F GR
Sbjct: 3 EHTEAGSAPEMGAQKALIDNPADILVIAAYFLLVIGVGLW-SMCRTNRGTVGGYFLAGRS 61
Query: 54 LAALPVGLSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLG 113
+ PVG SL AS + + +G+ GL L +L LF PV+ G
Sbjct: 62 MVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAG 121
Query: 114 LTSTYEYLEMRFS-RAVRL-CGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLST 171
+ + +YL RF R +RL L + + +++ A+ + Q G +I+AS+++
Sbjct: 122 VITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIAL 181
Query: 172 GIICTFYTAVGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVG----------GPRQVLT 221
I YT GG+ A+++TD Q V+L G +++ VG G LT
Sbjct: 182 LGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLT 241
Query: 222 LAQNHSRINLMDFNPDPR-SRYTFWTFVVGGTLVWLSM-----------YGVNQAQVQRY 269
++++ + N+ F PR Y V G L W ++ + +Q VQR
Sbjct: 242 VSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRC 301
Query: 270 VACRTEKQAKLALL----INQVGLFLIVSSAACCGIVMFVFYTD---------CDPLLLG 316
+A ++ K + + +FL+V G++ + Y D C +
Sbjct: 302 LAGKSLTHIKAGCILCGYLKLTPMFLMVMP----GMISRILYPDEVACVVPEVCRRVCGT 357
Query: 317 RISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLR 376
+ + P LV+ + + G+ GL LA + +S+ ++ N+ + + D I RLR
Sbjct: 358 EVGCSNIAYPRLVVKLMPN--GLRGLMLAVMLAALMSSLASIFNSSSTLFTMD-IYTRLR 414
Query: 377 SLA-PRKLVIISK-GLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILG 434
A R+L+++ + + I + + + + GG + V ++ P+ F+L
Sbjct: 415 PRAGDRELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLA 474
Query: 435 MFLPACNTPGVLAGLGAGLALSL 457
+F+P N G GL GL + L
Sbjct: 475 LFVPRVNEQGAFWGLIGGLLMGL 497
>gi|14140236 solute carrier family 5 (low affinity glucose
cotransporter), member 4 [Homo sapiens]
Length = 659
Score = 112 bits (280), Expect = 1e-24
Identities = 111/498 (22%), Positives = 208/498 (41%), Gaps = 57/498 (11%)
Query: 5 ETGERPTFG-----AWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPV 59
ET E P A D V + LV +GLW L + + + FF GR +A P+
Sbjct: 12 ETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAML-KTNRGTIGGFFLAGRDMAWWPM 70
Query: 60 GLSLSASFMSAVQVLGVPSEAYRYGLK---FLWMCLGQLLNSVLTALLFMPVFYRLGLTS 116
G SL AS + + +G+ G+ F W LL + +F+P++ + G+ +
Sbjct: 71 GASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLL---ILGWIFVPIYIKSGVMT 127
Query: 117 TYEYLEMRFS--RAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGII 174
EYL+ RF R L + +L I+A A+ + GLD++ ++ +
Sbjct: 128 MPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAM 187
Query: 175 CTFYTAVGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVL---------TLAQN 225
YT GG+ +V++TD Q ++ML G ++++ VGG + +
Sbjct: 188 TAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGD 247
Query: 226 HSRINLMDFNPDPRSRYTF---------WTFVVGG---TLVWLSMYGVNQAQVQRYVACR 273
+ I+ + P S + F W ++ G T +W + NQ VQR + +
Sbjct: 248 NLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALW--YWCTNQVIVQRCLCGK 305
Query: 274 TEKQAKLALL----INQVGLFLIVSSAACCGIVMFVFYTDCDPLLLGR---------ISA 320
K A + + + +FL+V G++ + YTD ++ +
Sbjct: 306 DMSHVKAACIMCAYLKLLPMFLMVMP----GMISRILYTDMVACVVPSECVKHCGVDVGC 361
Query: 321 PDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAP 380
+ P +VL++ G+ GL L+ + +S+ ++ N+ + + DL + +
Sbjct: 362 TNYAYPTMVLELMPQ--GLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASE 419
Query: 381 RKLVIISKGLSLIYGSACLT-VAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPA 439
++L+I + L+ + V + G ++ + ++ + P+ F+L +F
Sbjct: 420 KELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKR 479
Query: 440 CNTPGVLAGLGAGLALSL 457
N G GL GLA+ L
Sbjct: 480 VNEQGAFWGLMVGLAMGL 497
>gi|4507031 solute carrier family 5 (sodium/glucose cotransporter),
member 1 [Homo sapiens]
Length = 664
Score = 109 bits (272), Expect = 9e-24
Identities = 104/480 (21%), Positives = 204/480 (42%), Gaps = 44/480 (9%)
Query: 14 AWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQV 73
A D + + +V +GLW + + + FF GR + P+G SL AS + +
Sbjct: 26 AADISIIVIYFVVVMAVGLWAMFSTN-RGTVGGFFLAGRSMVWWPIGASLFASNIGSGHF 84
Query: 74 LGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS--RAVRL 131
+G+ G+ L+ V+ LF+P++ + G+ + EYL RF R
Sbjct: 85 VGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVY 144
Query: 132 CGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTD 191
L ++ I++ A+ +N GL+++ ++ I YT GG+ AV++TD
Sbjct: 145 LSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTD 204
Query: 192 VFQVVVMLSGFWVVLARGVMLVGG--------PRQVLTLAQNHS----------RINLMD 233
Q V+ML G ++ VGG + + T+ + + R +
Sbjct: 205 TLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFH 264
Query: 234 FNPDPRSRYTFWT-FVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAK----LALLINQVG 288
DP + W F+ G +++ L + +Q VQR ++ + K L + +
Sbjct: 265 IFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMP 324
Query: 289 LFLIVSSAACCGIVMFVFYT---------DCDPLLLGRISAPDQYMPLLVLDIFEDLPGV 339
+F++V G++ + YT +C+ ++ + P LV+++ + G+
Sbjct: 325 MFIMVMP----GMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GL 378
Query: 340 PGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISKGLSL--IYGSA 397
GL L+ + +S+ ++ N+ + + D I ++R A K ++I+ L + + G +
Sbjct: 379 RGLMLSVMLASLMSSLTSIFNSASTLFTMD-IYAKVRKRASEKELMIAGRLFILVLIGIS 437
Query: 398 CLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSL 457
V + S G + ++ + P+ F+L +F N PG GL GL + +
Sbjct: 438 IAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLIGI 497
>gi|109659836 solute carrier family 5 (sodium/glucose
cotransporter), member 10 isoform 2 [Homo sapiens]
Length = 596
Score = 107 bits (268), Expect = 3e-23
Identities = 128/586 (21%), Positives = 234/586 (39%), Gaps = 84/586 (14%)
Query: 16 DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75
D V + ++ +G+W R + + +F GR + P+G SL AS + +G
Sbjct: 20 DIIVITVYFALNVAVGIWSS-CRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIG 78
Query: 76 VPSEAYRYGLK---FLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS--RAVR 130
+ GL F W LL A +F+P++ + + EY++ R+ R
Sbjct: 79 LAGSGAAGGLAVAGFEWNATYVLL---ALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 135
Query: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190
L +++ + +YA AL ++ G + + S + T I YT GG+ AV++T
Sbjct: 136 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYT 195
Query: 191 DVFQVVVMLSGFWVVLARGVMLVGG-------------PRQVLTLAQNHSRINLMDFNPD 237
D Q ++M+ G ++ + +GG R + + R + M D
Sbjct: 196 DALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRD 255
Query: 238 PRSRYTFWTFVVGGTLVWLSMYG-VNQAQVQRYVACRTEKQAKLALLINQ------VGLF 290
P + WT + G + + Y +Q VQR ++ R AK ++ +GL
Sbjct: 256 PHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLI 315
Query: 291 L---IVSSAACCGIVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACA 347
+ ++S A V V ++C + + P LV+++ G+ GL +A
Sbjct: 316 IMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMP--IGLRGLMIAVM 373
Query: 348 YSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISK-GLSLIYGSACLTVAALSS 406
+ +S+ ++ N+ + + D+ + R+L+++ + + + G + + L
Sbjct: 374 LAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPVLQD 433
Query: 407 LLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLY 466
G + +V ++ P+ F+LG+F N G GL AGL +
Sbjct: 434 SNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVV----------- 482
Query: 467 PPSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAI 526
A R V +N AP G +RPA+ S I
Sbjct: 483 ------------GATRLVLEFLNP----------------APPCGEPDTRPAVLGS---I 511
Query: 527 SYLYYG-ALGTLT--TVLCGALISCLTGPTKRSTLAPGLLWWDLAR 569
YL++ AL L+ V+ G+L++ P +S L WW LA+
Sbjct: 512 HYLHFAVALFALSGAVVVAGSLLT----PPPQSVQIENLTWWTLAQ 553
>gi|110835708 solute carrier family 5 (inositol transporters),
member 3 [Homo sapiens]
Length = 718
Score = 102 bits (254), Expect = 1e-21
Identities = 104/479 (21%), Positives = 200/479 (41%), Gaps = 46/479 (9%)
Query: 16 DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75
D + AL ++ IG + + + + + +F GR + + +G SL S + + +G
Sbjct: 9 DIAIVALYFILVMCIGFFA-MWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEHFIG 67
Query: 76 VPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS--RAVRLCG 133
+ G LL L +F+P++ R G+ + EYL RF R
Sbjct: 68 LAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFA 127
Query: 134 TLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDVF 193
L I+ + +Y+ AL + + G +++ S++ + T GG+ AV++TD
Sbjct: 128 ALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTL 187
Query: 194 QVVVMLSGFWVVLARGVMLVGGPRQV-------------LTLAQNHSRINLMDFNP---- 236
Q ++M+ G ++ +M +GG +V + L N S N + +P
Sbjct: 188 QALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKKEA 247
Query: 237 -----DPRSRYTFWT-FVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAK----LALLINQ 286
+P W F++G T + + +Q VQR +A + AK +A +
Sbjct: 248 LKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKL 307
Query: 287 VGLFLIVSSAACCGIVMFVFYTD---------CDPLLLGRISAPDQYMPLLVLDIFEDLP 337
+ +F+IV G++ + +TD C + R + P LV+ +
Sbjct: 308 LPMFIIVVP----GMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVP--V 361
Query: 338 GVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISK-GLSLIYGS 396
G+ GL +A + +S + N+ + + D+ K +S + R+L+I+ + ++ +
Sbjct: 362 GLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVI 421
Query: 397 ACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLAL 455
+ V + + GG + V ++ P+ F+L +F CN G G AG L
Sbjct: 422 SIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL 480
>gi|109659839 solute carrier family 5 (sodium/glucose
cotransporter), member 10 isoform 1 [Homo sapiens]
Length = 612
Score = 101 bits (252), Expect = 2e-21
Identities = 128/602 (21%), Positives = 237/602 (39%), Gaps = 100/602 (16%)
Query: 16 DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75
D V + ++ +G+W R + + +F GR + P+G SL AS + +G
Sbjct: 20 DIIVITVYFALNVAVGIWSS-CRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIG 78
Query: 76 VPSEAYRYGLK---FLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS--RAVR 130
+ GL F W LL A +F+P++ + + EY++ R+ R
Sbjct: 79 LAGSGAAGGLAVAGFEWNATYVLL---ALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 135
Query: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190
L +++ + +YA AL ++ G + + S + T I YT GG+ AV++T
Sbjct: 136 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYT 195
Query: 191 DVFQVVVMLSGFWVVLARGVMLVGG-------------PRQVLTLAQNHSRINLMDFNPD 237
D Q ++M+ G ++ + +GG R + + R + M D
Sbjct: 196 DALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRD 255
Query: 238 PRSRYTFWTFVVGGTLVWLSMYG-VNQAQVQRYVACRTEKQAKLALLINQ------VGLF 290
P + WT + G + + Y +Q VQR ++ R AK ++ +GL
Sbjct: 256 PHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLI 315
Query: 291 LI---VSSAACCGIVMF----------------VFYTDCDPLLLGRISAPDQYMPLLVLD 331
++ +S A G ++ V ++C + + P LV++
Sbjct: 316 IMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVME 375
Query: 332 IFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISKGLS 391
+ G+ GL +A + +S+ ++ N+ + + D+ + R+L+++ + +
Sbjct: 376 LMPI--GLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVI 433
Query: 392 L-IYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLG 450
+ + G + + L G + +V ++ P+ F+LG+F N G GL
Sbjct: 434 VALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLI 493
Query: 451 AGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSS 510
AGL + A R V +N AP
Sbjct: 494 AGLVV-----------------------GATRLVLEFLNP----------------APPC 514
Query: 511 GMDASRPALADSFYAISYLYYG-ALGTLT--TVLCGALISCLTGPTKRSTLAPGLLWWDL 567
G +RPA+ S I YL++ AL L+ V+ G+L++ P +S L WW L
Sbjct: 515 GEPDTRPAVLGS---IHYLHFAVALFALSGAVVVAGSLLT----PPPQSVQIENLTWWTL 567
Query: 568 AR 569
A+
Sbjct: 568 AQ 569
>gi|206597483 solute carrier family 5 (sodium/glucose
cotransporter), member 9 isoform 2 [Homo sapiens]
Length = 681
Score = 100 bits (250), Expect = 3e-21
Identities = 126/584 (21%), Positives = 222/584 (38%), Gaps = 84/584 (14%)
Query: 14 AWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQV 73
A+D V + + +G+W + R + + +F GR ++ P+G SL +S + +
Sbjct: 35 AYDISVVVIYFVFVIAVGIWSSI-RASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLF 93
Query: 74 LGVPSEAYRYGLK---FLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS--RA 128
+G+ GL F W LL +F+PV+ G+ + +YL+ RF R
Sbjct: 94 IGLAGTGAAGGLAVGGFEWNATWLLL---ALGWVFVPVYIAAGVVTMPQYLKKRFGGQRI 150
Query: 129 VRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGI---ICTFYTAVGGMK 185
L I+ I++ AL + G W LSTGI + YT GG+
Sbjct: 151 QVYMSVLSLILYIFTKISTDIFSGALFIQMALG---WNLYLSTGILLVVTAVYTIAGGLM 207
Query: 186 AVVWTDVFQVVVMLSGFWVVLARGVMLVGG------------PRQVLTLAQNH-SRINLM 232
AV++TD Q V+M+ G V++ G VG P + H R +
Sbjct: 208 AVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAF 267
Query: 233 DFNPDPRSRYTFWT-FVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFL 291
DP S W + G T++ + +Q VQR ++ ++ AK ++ L
Sbjct: 268 HILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKIL 327
Query: 292 IVSSAACCGIVMFVFYTD---------CDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGL 342
+ G++ + D C + R+ + P LV+ + G+ GL
Sbjct: 328 PMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMP--VGLRGL 385
Query: 343 FLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISK-GLSLIYGSACLTV 401
+A + +S+ ++ N+ + + D+ + R ++L+++ + + + + L +
Sbjct: 386 MIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWI 445
Query: 402 AALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVAL 461
+ S G + V ++ P+ F+L +F PG GL GL + L +
Sbjct: 446 PIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVGLLRMI 505
Query: 462 GATLYPPSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALAD 521
YP AP+ G RPA+
Sbjct: 506 LEFSYP---------------------------------------APACGEVDRRPAVLK 526
Query: 522 SFYAISYLYYGALGTLTTVLCGALISCLTGPTKRSTLAPGLLWW 565
F+ YLY+ L T + ++S T P L L WW
Sbjct: 527 DFH---YLYFAILLCGLTAIVIVIVSLCTTPIPEEQLT-RLTWW 566
>gi|206597487 solute carrier family 5 (sodium/glucose
cotransporter), member 9 isoform 1 [Homo sapiens]
Length = 706
Score = 91.3 bits (225), Expect = 3e-18
Identities = 128/606 (21%), Positives = 224/606 (36%), Gaps = 103/606 (16%)
Query: 14 AWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQV 73
A+D V + + +G+W + R + + +F GR ++ P+G SL +S + +
Sbjct: 35 AYDISVVVIYFVFVIAVGIWSSI-RASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLF 93
Query: 74 LGVPSEAYRYGLK---FLWMCLGQL----------------LNSVLTALL------FMPV 108
+G+ GL F W + S T LL F+PV
Sbjct: 94 IGLAGTGAAGGLAVGGFEWNMRKSRSGGDRGIHPRSHGRTGVRSQATWLLLALGWVFVPV 153
Query: 109 FYRLGLTSTYEYLEMRFS--RAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWA 166
+ G+ + +YL+ RF R L I+ I++ AL + G W
Sbjct: 154 YIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALG---WN 210
Query: 167 SLLSTGI---ICTFYTAVGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGG-------- 215
LSTGI + YT GG+ AV++TD Q V+M+ G V++ G VG
Sbjct: 211 LYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRY 270
Query: 216 ----PRQVLTLAQNH-SRINLMDFNPDPRSRYTFWT-FVVGGTLVWLSMYGVNQAQVQRY 269
P + H R + DP S W + G T++ + +Q VQR
Sbjct: 271 RQAIPNVTVPNTTCHLPRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRS 330
Query: 270 VACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTD---------CDPLLLGRISA 320
++ ++ AK ++ L + G++ + D C + R+
Sbjct: 331 LSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGC 390
Query: 321 PDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAP 380
+ P LV+ + G+ GL +A + +S+ ++ N+ + + D+ + R
Sbjct: 391 SNIAYPKLVMALMP--VGLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTE 448
Query: 381 RKLVIISK-GLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPA 439
++L+++ + + + + L + + S G + V ++ P+ F+L +F
Sbjct: 449 QELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKR 508
Query: 440 CNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALSVNASGLLDPALL 499
PG GL GL + L + YP
Sbjct: 509 VTEPGAFWGLVFGLGVGLLRMILEFSYP-------------------------------- 536
Query: 500 PANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLTGPTKRSTLA 559
AP+ G RPA+ F+ YLY+ L T + ++S T P L
Sbjct: 537 -------APACGEVDRRPAVLKDFH---YLYFAILLCGLTAIVIVIVSLCTTPIPEEQLT 586
Query: 560 PGLLWW 565
L WW
Sbjct: 587 -RLTWW 591
>gi|11141885 solute carrier family 5 (choline transporter), member 7
[Homo sapiens]
Length = 580
Score = 77.0 bits (188), Expect = 5e-14
Identities = 94/461 (20%), Positives = 190/461 (41%), Gaps = 48/461 (10%)
Query: 19 VFALMLLVSTGIGLWVGLARGGQRSAED----FFTGGRRLAALPVGLSLSASFMSAVQVL 74
VF L++L+ +G+W SAE+ GGR + L G +++A+++ +
Sbjct: 13 VFYLLILL---VGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYIN 69
Query: 75 GVPSEAY--RYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLC 132
G Y YGL + +G L+ +L L F G + + + + + +
Sbjct: 70 GTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGL 129
Query: 133 GTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDV 192
+ ++ M + + A ++ + +D+ S++ + +I T YT VGG+ +V +TDV
Sbjct: 130 LFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDV 189
Query: 193 FQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVGGT 252
Q+ + G W+ + A +H + + F W V +
Sbjct: 190 VQLFCIFVGLWI--------------SVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSS 235
Query: 253 LV--WLSMY------GVN-QAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVM 303
V WL + G+ QA QR ++ + A++ + G ++ A G +
Sbjct: 236 EVYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAI- 294
Query: 304 FVFYTDCDPLLLG-----RISAPDQYMPLLVLDIFEDLPGVPGLF-LACAYSGTLSTAST 357
TD + G D +P+++ + P F L + +S+A +
Sbjct: 295 -GASTDWNQTAYGLPDPKTTEEADMILPIVLQYL---CPVYISFFGLGAVSAAVMSSADS 350
Query: 358 SINAMAAVTVEDLIKPRLR-SLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGS 416
SI + +++ ++ + R + + +++V + + ++G++ +A L+ + G S
Sbjct: 351 SILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSS 410
Query: 417 FTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSL 457
V VI LL +F+ NT G +AG +GL L +
Sbjct: 411 DLVYIVIFPQLLCV----LFVKGTNTYGAVAGYVSGLFLRI 447
>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo
sapiens]
Length = 2365
Score = 33.9 bits (76), Expect = 0.48
Identities = 45/175 (25%), Positives = 68/175 (38%), Gaps = 24/175 (13%)
Query: 486 LSVNASG---LLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLC 542
LS + SG ++DP L P +PS+G+ P A + L LTT LC
Sbjct: 64 LSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLC 123
Query: 543 GALISCLTGPTKRSTLAP-----------GLLWWDLARQTASVAPK-EEVAILDDNLVKG 590
G SC P T +P + WD + AP +E+A++ + +
Sbjct: 124 G---SCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVM---IPRR 177
Query: 591 PEELP--TGNKKPPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL 643
P E P +++ P L + GQK+ E G G R + E+ L
Sbjct: 178 PREGPRADSSQRAPSLLTRSPVGGDAAGQKK-EDTGGGGRSAGQHWARLRGESGL 231
>gi|239745235 PREDICTED: hypothetical protein [Homo sapiens]
Length = 664
Score = 33.5 bits (75), Expect = 0.62
Identities = 46/163 (28%), Positives = 62/163 (38%), Gaps = 19/163 (11%)
Query: 444 GVLAGLGAGLALS-LWVALGATLYPPSEQTMRVLPSSAARCVALSVNAS----------G 492
GV L AG+ L+ LW+ + L PS P SA AL N+
Sbjct: 2 GVQWLLAAGILLAALWMVSASALNLPSTHKDPGWPPSAPGTSALQGNSKKTLLSLNILPA 61
Query: 493 LLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLTGP 552
++D L A APS+ +A P ++ A L +L + A+ S G
Sbjct: 62 IVDGVSLSAERKGEAPSTRAEALSPEVSGDQEAPLAL------SLDSSSDQAVPSGTAGV 115
Query: 553 TKRSTL--APGLLWWDLARQTASVAPKEEVAILDDNLVKGPEE 593
R+ AP L W A +T P VA L V GP E
Sbjct: 116 PGRAPPGPAPSALAWPTAHRTPESQPVSSVAGLVSGSVAGPAE 158
>gi|26024197 diacylglycerol O-acyltransferase 2 [Homo sapiens]
Length = 388
Score = 30.8 bits (68), Expect = 4.0
Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Query: 273 RTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTDC 310
+ EKQ ++ ++ V FL++ AC I+M++F TDC
Sbjct: 63 KVEKQLQVISVLQWVLSFLVLG-VACSAILMYIFCTDC 99
>gi|54019430 olfactory receptor, family 6, subfamily C, member 75
[Homo sapiens]
Length = 312
Score = 30.8 bits (68), Expect = 4.0
Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 28/114 (24%)
Query: 85 LKFLWMCLGQLLNSVLT-----------ALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCG 133
+ F +C+ + L +V+T A LF +F LG+T Y M + R + +C
Sbjct: 69 ISFTSVCIPRFLVTVVTGNRTISYNGCVAQLFFFIF--LGVTEFYLLAAMSYDRCMAICK 126
Query: 134 TLQY------------IVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIIC 175
L Y + ++ L ++I+ P ++L Q LD AS + IC
Sbjct: 127 PLHYTIIMSTRVCTLLVFSSWLAGFLIIFPPVMLLLQ---LDFCASNVIDHFIC 177
>gi|118582267 equilibrative nucleoside transporter 1 [Homo sapiens]
Length = 456
Score = 30.0 bits (66), Expect = 6.9
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 92 LGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCGTLQYIVATMLYTGIVI 149
L + N+V+T +P+ L S +L R ++VR+ G+L I+ L T I++
Sbjct: 76 LSAIFNNVMTLCAMLPLLLFTYLNS---FLHQRIPQSVRILGSLVAILLVFLITAILV 130
>gi|118582265 equilibrative nucleoside transporter 1 [Homo sapiens]
Length = 456
Score = 30.0 bits (66), Expect = 6.9
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 92 LGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCGTLQYIVATMLYTGIVI 149
L + N+V+T +P+ L S +L R ++VR+ G+L I+ L T I++
Sbjct: 76 LSAIFNNVMTLCAMLPLLLFTYLNS---FLHQRIPQSVRILGSLVAILLVFLITAILV 130
>gi|118582262 equilibrative nucleoside transporter 1 [Homo sapiens]
Length = 456
Score = 30.0 bits (66), Expect = 6.9
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 92 LGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCGTLQYIVATMLYTGIVI 149
L + N+V+T +P+ L S +L R ++VR+ G+L I+ L T I++
Sbjct: 76 LSAIFNNVMTLCAMLPLLLFTYLNS---FLHQRIPQSVRILGSLVAILLVFLITAILV 130
>gi|118582260 equilibrative nucleoside transporter 1 [Homo sapiens]
Length = 456
Score = 30.0 bits (66), Expect = 6.9
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 92 LGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCGTLQYIVATMLYTGIVI 149
L + N+V+T +P+ L S +L R ++VR+ G+L I+ L T I++
Sbjct: 76 LSAIFNNVMTLCAMLPLLLFTYLNS---FLHQRIPQSVRILGSLVAILLVFLITAILV 130
>gi|4826716 equilibrative nucleoside transporter 1 [Homo sapiens]
Length = 456
Score = 30.0 bits (66), Expect = 6.9
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 92 LGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCGTLQYIVATMLYTGIVI 149
L + N+V+T +P+ L S +L R ++VR+ G+L I+ L T I++
Sbjct: 76 LSAIFNNVMTLCAMLPLLLFTYLNS---FLHQRIPQSVRILGSLVAILLVFLITAILV 130
>gi|50080213 olfactory receptor, family 6, subfamily C, member 3
[Homo sapiens]
Length = 311
Score = 30.0 bits (66), Expect = 6.9
Identities = 27/117 (23%), Positives = 48/117 (41%), Gaps = 28/117 (23%)
Query: 85 LKFLWMCLGQLLNSVLT-----------ALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCG 133
+ F +C+ + L +++T A LF +F +G+T Y M + R V +C
Sbjct: 68 ISFTTVCIPRFLGAIITRNKTISYNNCAAQLFFFIF--MGVTEFYILTAMSYDRYVAICK 125
Query: 134 TLQY------------IVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFY 178
L Y ++ L + I+ P ++L Q LD AS + C ++
Sbjct: 126 PLHYTSIMNRKLCTLLVLCAWLSGFLTIFPPLMLLLQ---LDYCASNVIDHFACDYF 179
>gi|13376816 CXXC finger 4 [Homo sapiens]
Length = 198
Score = 29.6 bits (65), Expect = 9.0
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 2/61 (3%)
Query: 460 ALGATLYPPSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSS--GMDASRP 517
ALG PP M L S AA A++ +A + + A P N SS + SS G + P
Sbjct: 72 ALGGISLPPGVIVMTALHSPAAASAAVTDSAFQIANLADCPQNHSSSSSSSSGGAGGANP 131
Query: 518 A 518
A
Sbjct: 132 A 132
>gi|139394648 DNA polymerase theta [Homo sapiens]
Length = 2590
Score = 29.6 bits (65), Expect = 9.0
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 570 QTASVAPKEEVAILDDNLVKGPEELPTGNKKP--PGFLPT 607
+T+S+ P++E I+DDN + P +PT K PG L T
Sbjct: 1716 ETSSLLPRKESNIVDDNGLIPPTPIPTSASKLTFPGILET 1755
>gi|55953085 G protein-coupled receptor 120 [Homo sapiens]
Length = 377
Score = 29.6 bits (65), Expect = 9.0
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 25/117 (21%)
Query: 289 LFLIVSSAACCGIVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPG---------- 338
L LI +A + + VF+ ++ R+ DQ + + L I+ +PG
Sbjct: 159 LALIWGYSAVAALPLCVFFR----VVPQRLPGADQEISICTL-IWPTIPGEISWDVSFVT 213
Query: 339 ----VPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISKGLS 391
VPGL + +YS L T+ ++A A VT ++ K A RK + +S S
Sbjct: 214 LNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITK------ASRKRLTVSLAYS 264
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,977,459
Number of Sequences: 37866
Number of extensions: 1073355
Number of successful extensions: 2565
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2518
Number of HSP's gapped (non-prelim): 30
length of query: 643
length of database: 18,247,518
effective HSP length: 109
effective length of query: 534
effective length of database: 14,120,124
effective search space: 7540146216
effective search space used: 7540146216
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.