Guide to the Human Genome
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Search of human proteins with 4506163

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506163 presenilin 1 isoform I-467 [Homo sapiens]
         (467 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506163 presenilin 1 isoform I-467 [Homo sapiens]                  926   0.0  
gi|195947397 presenilin 1 isoform I-463 [Homo sapiens]                913   0.0  
gi|156105679 presenilin 2 isoform 1 [Homo sapiens]                    558   e-159
gi|156105681 presenilin 2 isoform 2 [Homo sapiens]                    556   e-158
gi|68223315 CD47 antigen isoform 3 precursor [Homo sapiens]            42   0.002
gi|38683836 CD47 antigen isoform 2 precursor [Homo sapiens]            42   0.002
gi|4502673 CD47 antigen isoform 1 precursor [Homo sapiens]             42   0.002
gi|4826934 protein phosphatase 4, regulatory subunit 1 isoform b...    34   0.32 
gi|108936953 protein phosphatase 4, regulatory subunit 1 isoform...    34   0.32 
gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo ...    32   1.2  
gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo ...    32   1.2  
gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo ...    32   1.2  
gi|118582255 ATP-binding cassette, sub-family C, member 8 [Homo ...    32   1.6  
gi|40789233 coenzyme Q9 homolog [Homo sapiens]                         31   2.7  
gi|4502805 chromogranin A precursor [Homo sapiens]                     31   2.7  
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom...    31   2.7  
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom...    31   2.7  
gi|197313748 SET domain containing 2 [Homo sapiens]                    31   2.7  
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]       31   2.7  
gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]            31   2.7  
gi|18034692 CDW92 antigen [Homo sapiens]                               31   2.7  
gi|148228819 G protein-coupled receptor 89A isoform 1 [Homo sapi...    30   4.7  
gi|7706704 G protein-coupled receptor 89B [Homo sapiens]               30   4.7  
gi|94721321 coiled-coil domain containing 11 [Homo sapiens]            30   4.7  
gi|156416026 zinc finger protein 219 [Homo sapiens]                    30   4.7  
gi|156415998 zinc finger protein 219 [Homo sapiens]                    30   4.7  
gi|52218862 olfactory receptor, family 13, subfamily J, member 1...    30   4.7  
gi|156415996 zinc finger protein 219 [Homo sapiens]                    30   4.7  
gi|57977305 G protein-coupled receptor 151 [Homo sapiens]              30   4.7  
gi|41281808 harmonin isoform b3 [Homo sapiens]                         30   6.1  

>gi|4506163 presenilin 1 isoform I-467 [Homo sapiens]
          Length = 467

 Score =  926 bits (2393), Expect = 0.0
 Identities = 467/467 (100%), Positives = 467/467 (100%)

Query: 1   MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSR 60
           MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSR
Sbjct: 1   MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSR 60

Query: 61  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE 120
           QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE
Sbjct: 61  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE 120

Query: 121 DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI 180
           DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI
Sbjct: 121 DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI 180

Query: 181 YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY 240
           YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY
Sbjct: 181 YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY 240

Query: 241 LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE 300
           LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
Sbjct: 241 LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE 300

Query: 301 GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA 360
           GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA
Sbjct: 301 GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA 360

Query: 361 VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL 420
           VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL
Sbjct: 361 VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL 420

Query: 421 TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 467
           TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
Sbjct: 421 TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 467


>gi|195947397 presenilin 1 isoform I-463 [Homo sapiens]
          Length = 463

 Score =  913 bits (2360), Expect = 0.0
 Identities = 463/467 (99%), Positives = 463/467 (99%), Gaps = 4/467 (0%)

Query: 1   MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSR 60
           MTELPAPLSYFQNAQMSEDNHLSNT    NDNRERQEHNDRRSLGHPEPLSNGRPQGNSR
Sbjct: 1   MTELPAPLSYFQNAQMSEDNHLSNT----NDNRERQEHNDRRSLGHPEPLSNGRPQGNSR 56

Query: 61  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE 120
           QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE
Sbjct: 57  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE 116

Query: 121 DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI 180
           DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI
Sbjct: 117 DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI 176

Query: 181 YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY 240
           YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY
Sbjct: 177 YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY 236

Query: 241 LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE 300
           LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
Sbjct: 237 LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE 296

Query: 301 GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA 360
           GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA
Sbjct: 297 GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA 356

Query: 361 VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL 420
           VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL
Sbjct: 357 VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL 416

Query: 421 TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 467
           TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
Sbjct: 417 TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 463


>gi|156105679 presenilin 2 isoform 1 [Homo sapiens]
          Length = 448

 Score =  558 bits (1438), Expect = e-159
 Identities = 306/466 (65%), Positives = 345/466 (74%), Gaps = 42/466 (9%)

Query: 3   ELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSL-GHPEPLSNGRPQGNSRQ 61
           E P P S  +  Q  ED   +   RSQ +  + +E  DR    G P     GRP G    
Sbjct: 24  ESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDPDRYVCSGVP-----GRPPGL--- 75

Query: 62  VVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTED 121
                   +EELTLKYGAKHVIMLFVPVTLCM+VVVATIKSV FYT K+GQLIYTPFTED
Sbjct: 76  --------EEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTED 127

Query: 122 TETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIY 181
           T +VGQR L+S+LN  IMISVIVVMTI LVVLYKYRCYK IH WLI+SSL+LLF F++IY
Sbjct: 128 TPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIY 187

Query: 182 LGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYL 241
           LGEV KTYNVA+DY T+ L +WNFG VGM+ IHWKGPL LQQAYLIMISALMALVFIKYL
Sbjct: 188 LGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYL 247

Query: 242 PEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEG 301
           PEW+AW+IL  ISVYDLVAVLCPKGPLRMLVETAQERNE +FPALIYSS MVW V MA+ 
Sbjct: 248 PEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKL 307

Query: 302 DPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAV 361
           DP +Q  +     Y+ E  E +S D+  E     + E +E     + G            
Sbjct: 308 DPSSQGAL--QLPYDPE-MEEDSYDSFGE---PSYPEVFEPPLTGYPG------------ 349

Query: 362 QELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLT 421
           +EL       E+ EERGVKLGLGDFIFYSVLVGKA+AT SGDWNTT+ACFVAILIGLCLT
Sbjct: 350 EEL-------EEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLT 402

Query: 422 LLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 467
           LLLLA+FKKALPALPISITFGL+FYF+TD LV+PFMD LA HQ YI
Sbjct: 403 LLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 448


>gi|156105681 presenilin 2 isoform 2 [Homo sapiens]
          Length = 447

 Score =  556 bits (1433), Expect = e-158
 Identities = 302/466 (64%), Positives = 342/466 (73%), Gaps = 43/466 (9%)

Query: 3   ELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSL-GHPEPLSNGRPQGNSRQ 61
           E P P S  +  Q  ED   +   RSQ +  + +E  DR    G P     GRP G    
Sbjct: 24  ESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDPDRYVCSGVP-----GRPPGL--- 75

Query: 62  VVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTED 121
                   +EELTLKYGAKHVIMLFVPVTLCM+VVVATIKSV FYT K+GQLIYTPFTED
Sbjct: 76  --------EEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTED 127

Query: 122 TETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIY 181
           T +VGQR L+S+LN  IMISVIVVMTI LVVLYKYRCYK IH WLI+SSL+LLF F++IY
Sbjct: 128 TPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIY 187

Query: 182 LGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYL 241
           LGEV KTYNVA+DY T+ L +WNFG VGM+ IHWKGPL LQQAYLIMISALMALVFIKYL
Sbjct: 188 LGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYL 247

Query: 242 PEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEG 301
           PEW+AW+IL  ISVYDLVAVLCPKGPLRMLVETAQERNE +FPALIYSS MVW V MA+ 
Sbjct: 248 PEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKL 307

Query: 302 DPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAV 361
           DP +Q  +           + E +D+     +  + E +E     + G            
Sbjct: 308 DPSSQGALQL-------PYDPEMEDSYDSFGEPSYPEVFEPPLTGYPG------------ 348

Query: 362 QELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLT 421
           +EL       E+ EERGVKLGLGDFIFYSVLVGKA+AT SGDWNTT+ACFVAILIGLCLT
Sbjct: 349 EEL-------EEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLT 401

Query: 422 LLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI 467
           LLLLA+FKKALPALPISITFGL+FYF+TD LV+PFMD LA HQ YI
Sbjct: 402 LLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI 447


>gi|68223315 CD47 antigen isoform 3 precursor [Homo sapiens]
          Length = 312

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/187 (20%), Positives = 83/187 (44%), Gaps = 15/187 (8%)

Query: 61  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLI-YTPFT 119
           +V E   E +  + LKY    V+  F P    ++V+      + F+ +   + + Y    
Sbjct: 115 EVTELTREGETIIELKY---RVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGG 171

Query: 120 EDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSF 179
            D +T+      ++L A ++I+VIV++  +L V  +Y         LI++S  +L    +
Sbjct: 172 MDEKTI------ALLVAGLVITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHY 225

Query: 180 IYLGEVFKTYNVAVDYITVALLIWNFGVVGM-----ISIHWKGPLRLQQAYLIMISALMA 234
                     +  +  + + ++ +   VVG+       I   GPL +    ++ ++ L+ 
Sbjct: 226 YVFSTAIGLTSFVIAILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLG 285

Query: 235 LVFIKYL 241
           LV++K++
Sbjct: 286 LVYMKFV 292


>gi|38683836 CD47 antigen isoform 2 precursor [Homo sapiens]
          Length = 305

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/187 (20%), Positives = 83/187 (44%), Gaps = 15/187 (8%)

Query: 61  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLI-YTPFT 119
           +V E   E +  + LKY    V+  F P    ++V+      + F+ +   + + Y    
Sbjct: 115 EVTELTREGETIIELKY---RVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGG 171

Query: 120 EDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSF 179
            D +T+      ++L A ++I+VIV++  +L V  +Y         LI++S  +L    +
Sbjct: 172 MDEKTI------ALLVAGLVITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHY 225

Query: 180 IYLGEVFKTYNVAVDYITVALLIWNFGVVGM-----ISIHWKGPLRLQQAYLIMISALMA 234
                     +  +  + + ++ +   VVG+       I   GPL +    ++ ++ L+ 
Sbjct: 226 YVFSTAIGLTSFVIAILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLG 285

Query: 235 LVFIKYL 241
           LV++K++
Sbjct: 286 LVYMKFV 292


>gi|4502673 CD47 antigen isoform 1 precursor [Homo sapiens]
          Length = 323

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/187 (20%), Positives = 83/187 (44%), Gaps = 15/187 (8%)

Query: 61  QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLI-YTPFT 119
           +V E   E +  + LKY    V+  F P    ++V+      + F+ +   + + Y    
Sbjct: 115 EVTELTREGETIIELKY---RVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGG 171

Query: 120 EDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSF 179
            D +T+      ++L A ++I+VIV++  +L V  +Y         LI++S  +L    +
Sbjct: 172 MDEKTI------ALLVAGLVITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHY 225

Query: 180 IYLGEVFKTYNVAVDYITVALLIWNFGVVGM-----ISIHWKGPLRLQQAYLIMISALMA 234
                     +  +  + + ++ +   VVG+       I   GPL +    ++ ++ L+ 
Sbjct: 226 YVFSTAIGLTSFVIAILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLG 285

Query: 235 LVFIKYL 241
           LV++K++
Sbjct: 286 LVYMKFV 292


>gi|4826934 protein phosphatase 4, regulatory subunit 1 isoform b
           [Homo sapiens]
          Length = 933

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 3/119 (2%)

Query: 265 KGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERES 324
           K  LR  V T  + +  L    +Y+S   W   + E D + +   +   K + E  E ES
Sbjct: 414 KSMLRPEVGTTSQ-DSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEES 472

Query: 325 QDTVAENDDGGFSEEWEAQR-DSHLGPHRSTPESRAAVQELSSSILAGE-DPEERGVKL 381
           +  V  + +   +   E +    +L PH   P+ +A V+ LS+++ A   D  E  + +
Sbjct: 473 EGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISI 531


>gi|108936953 protein phosphatase 4, regulatory subunit 1 isoform a
           [Homo sapiens]
          Length = 950

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 3/119 (2%)

Query: 265 KGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERES 324
           K  LR  V T  + +  L    +Y+S   W   + E D + +   +   K + E  E ES
Sbjct: 431 KSMLRPEVGTTSQ-DSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEES 489

Query: 325 QDTVAENDDGGFSEEWEAQR-DSHLGPHRSTPESRAAVQELSSSILAGE-DPEERGVKL 381
           +  V  + +   +   E +    +L PH   P+ +A V+ LS+++ A   D  E  + +
Sbjct: 490 EGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISI 548


>gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo
           sapiens]
          Length = 426

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)

Query: 381 LGLGDF----IFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL- 435
           LGLGD     IF ++L+    +            F A + GL LT+ ++ IFK A PAL 
Sbjct: 261 LGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALL 320

Query: 436 ---PISITFGLVFYFATDYLVQPF 456
              P  I F ++   A   + + F
Sbjct: 321 YLVPACIGFPVLVALAKGEVTEMF 344


>gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo
           sapiens]
          Length = 394

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)

Query: 381 LGLGDF----IFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL- 435
           LGLGD     IF ++L+    +            F A + GL LT+ ++ IFK A PAL 
Sbjct: 261 LGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALL 320

Query: 436 ---PISITFGLVFYFATDYLVQPF 456
              P  I F ++   A   + + F
Sbjct: 321 YLVPACIGFPVLVALAKGEVTEMF 344


>gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo
           sapiens]
          Length = 377

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)

Query: 381 LGLGDF----IFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL- 435
           LGLGD     IF ++L+    +            F A + GL LT+ ++ IFK A PAL 
Sbjct: 261 LGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALL 320

Query: 436 ---PISITFGLVFYFATDYLVQPF 456
              P  I F ++   A   + + F
Sbjct: 321 YLVPACIGFPVLVALAKGEVTEMF 344


>gi|118582255 ATP-binding cassette, sub-family C, member 8 [Homo
           sapiens]
          Length = 1581

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 3/65 (4%)

Query: 8   LSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDE 67
           L  FQ ++     H    +  Q+   E++   +R++   P+ LS      +SR  + QDE
Sbjct: 913 LKDFQRSECQLFEHWKTLMNRQDQELEKETVTERKATEPPQGLSRAM---SSRDGLLQDE 969

Query: 68  EEDEE 72
           EE+EE
Sbjct: 970 EEEEE 974


>gi|40789233 coenzyme Q9 homolog [Homo sapiens]
          Length = 318

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 17/66 (25%), Positives = 33/66 (50%)

Query: 23  SNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHV 82
           S+  + Q  N   Q+H++ +    P+P S+  P   + Q  E++E+ + E  L++     
Sbjct: 47  SDEQKQQPPNSFSQQHSETQGAEKPDPESSHSPPRYTDQGGEEEEDYESEEQLQHRILTA 106

Query: 83  IMLFVP 88
            + FVP
Sbjct: 107 ALEFVP 112


>gi|4502805 chromogranin A precursor [Homo sapiens]
          Length = 457

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 14/58 (24%), Positives = 31/58 (53%), Gaps = 4/58 (6%)

Query: 18  EDNHLSNTVRSQNDNRERQEHNDR----RSLGHPEPLSNGRPQGNSRQVVEQDEEEDE 71
           E+    + +  + D++E ++  +     R    PEP+   + +GN++   E++EEE+E
Sbjct: 122 EEPSSKDVMEKREDSKEAEKSGEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEE 179


>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
            sapiens]
          Length = 1108

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 16/60 (26%), Positives = 28/60 (46%)

Query: 14   AQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEEL 73
            +Q   D   S T     D+ + +E  D+      E     +PQG+  +  E++E E+EE+
Sbjct: 1002 SQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEV 1061


>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
            sapiens]
          Length = 1124

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 16/60 (26%), Positives = 28/60 (46%)

Query: 14   AQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEEL 73
            +Q   D   S T     D+ + +E  D+      E     +PQG+  +  E++E E+EE+
Sbjct: 1018 SQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEV 1077


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 2    TELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRS--LGHPEPLSNGRPQGNS 59
            TE    +S+ Q+++   DN L      Q+D  +   H D +S  LGHP      + +  S
Sbjct: 1137 TEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPS 1196

Query: 60   RQVVE 64
            RQ  E
Sbjct: 1197 RQQEE 1201


>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
          Length = 1134

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 34/159 (21%), Positives = 61/159 (38%), Gaps = 39/159 (24%)

Query: 139  MISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITV 198
            ++  ++V T+ L +      +  I+ ++I  SLL    FS ++ G               
Sbjct: 1007 LVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGG--------------- 1051

Query: 199  ALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDL 258
              +IW F             L  Q+ Y          VFI+ L    AWL + ++    L
Sbjct: 1052 --VIWPF-------------LNYQRMYY---------VFIQMLSSGPAWLAIVLLVTISL 1087

Query: 259  VAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVN 297
            +  +  K   R L  TA ER +T    L    + +++++
Sbjct: 1088 LPDVLKKVLCRQLWPTATERVQTKSQCLSVEQSTIFMLS 1126


>gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]
          Length = 520

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 3/58 (5%)

Query: 381 LGLGDFIFYSVLVG---KASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL 435
           LG GD I   +L+    +        +   ++  VA  IG+ LT ++L + KK  PAL
Sbjct: 408 LGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPAL 465


>gi|18034692 CDW92 antigen [Homo sapiens]
          Length = 657

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 38/235 (16%), Positives = 93/235 (39%), Gaps = 12/235 (5%)

Query: 51  SNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKD 110
           + G P  N +  VE       +    Y    +I +   +  C  + VA      ++TR  
Sbjct: 361 TTGSPVQNEQGFVEFKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDK 420

Query: 111 GQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLY------KYRCYKVIHA 164
             L +TP       + +  L ++   + +I+++ +  ++L+ ++      +  C + +  
Sbjct: 421 RNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLKGKENACARCVLK 480

Query: 165 WLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVA-----LLIWNFGVVGMISIHWKGPL 219
             I     L    +++       T   + ++ T A     +L+ N   V  I+      L
Sbjct: 481 SCICCLWCLEKCLNYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVATINTVGDFML 540

Query: 220 RLQQAYLIMISALMALVFIKYLPEWTAWLI-LAVISVYDLVAVLCPKGPLRMLVE 273
            L +  ++  + L  ++ + Y  ++T W++ L ++ ++  +   C      M+V+
Sbjct: 541 FLGKVLIVCSTGLAGIMLLNYQQDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVD 595


>gi|148228819 G protein-coupled receptor 89A isoform 1 [Homo
           sapiens]
          Length = 455

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 18/85 (21%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 128 RALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIY--LGEV 185
           R  H  +N  +++ ++V M    +  +     +++H   ++ S LL   F + +  LG+ 
Sbjct: 71  RYFHWKMNLCVILLILVFMVPFYIGYFIVSNIRLLHKQRLLFSCLLWLTFMYFFWKLGDP 130

Query: 186 FKTYNVAVDYITVALLIWNFGVVGM 210
           F   +     +++  LI   GV+G+
Sbjct: 131 FPILSPKHGILSIEQLISRVGVIGV 155


>gi|7706704 G protein-coupled receptor 89B [Homo sapiens]
          Length = 455

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 18/85 (21%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 128 RALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIY--LGEV 185
           R  H  +N  +++ ++V M    +  +     +++H   ++ S LL   F + +  LG+ 
Sbjct: 71  RYFHWKMNLCVILLILVFMVPFYIGYFIVSNIRLLHKQRLLFSCLLWLTFMYFFWKLGDP 130

Query: 186 FKTYNVAVDYITVALLIWNFGVVGM 210
           F   +     +++  LI   GV+G+
Sbjct: 131 FPILSPKHGILSIEQLISRVGVIGV 155


>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
          Length = 514

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 5/74 (6%)

Query: 304 EAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRS--TPESRAAV 361
           E + R+ + +K   E  E+E QD VAE  D  F E  E  R   L  H+     E +A +
Sbjct: 125 EKKDRMREKTKLLKEKNEKERQDFVAEKLDQQFRERCEELRVELLSIHQKKVCEERKAQI 184

Query: 362 ---QELSSSILAGE 372
              +ELS   L  E
Sbjct: 185 AFNEELSRQKLVEE 198


>gi|156416026 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 22/67 (32%), Positives = 27/67 (40%)

Query: 5   PAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVE 64
           PAP    +    S   +LS        N E  E    RS G   PLS+  P    R   E
Sbjct: 365 PAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAE 424

Query: 65  QDEEEDE 71
           + EEE+E
Sbjct: 425 EPEEEEE 431


>gi|156415998 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 22/67 (32%), Positives = 27/67 (40%)

Query: 5   PAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVE 64
           PAP    +    S   +LS        N E  E    RS G   PLS+  P    R   E
Sbjct: 365 PAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAE 424

Query: 65  QDEEEDE 71
           + EEE+E
Sbjct: 425 EPEEEEE 431


>gi|52218862 olfactory receptor, family 13, subfamily J, member 1
           [Homo sapiens]
          Length = 312

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 116 TPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLF 175
           T  +ED    G   L  +  A I +S ++++  +L V    RC K     L   +++LLF
Sbjct: 192 TSVSEDFLLAGSILLLPVPLAFICLSYLLILATILRVPSAARCCKAFSTCLAHLAVVLLF 251

Query: 176 FFS--FIYLGEVFKTYNVAVDYITV 198
           + +  F+YL    K  +++ +  TV
Sbjct: 252 YGTIIFMYLKPKSKEAHISDEVFTV 276


>gi|156415996 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 22/67 (32%), Positives = 27/67 (40%)

Query: 5   PAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVE 64
           PAP    +    S   +LS        N E  E    RS G   PLS+  P    R   E
Sbjct: 365 PAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAE 424

Query: 65  QDEEEDE 71
           + EEE+E
Sbjct: 425 EPEEEEE 431


>gi|57977305 G protein-coupled receptor 151 [Homo sapiens]
          Length = 419

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 16/110 (14%)

Query: 227 IMISALMALVFIKYLPEWTAWLILAVISVYDLVAV--LCPKGPLRMLVETAQERNETLFP 284
           +M+ ++  +  + +LPEW AWL      V+ L A     P+G + +        ++ L  
Sbjct: 250 VMLLSIAIISALLWLPEWVAWL-----WVWHLKAAGPAPPQGFIAL--------SQVLMF 296

Query: 285 ALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDG 334
           ++  ++ +++LV M+E   E  + V K        T  ESQ+T A N +G
Sbjct: 297 SISSANPLIFLV-MSEEFREGLKGVWKWMITKKPPTVSESQETPAGNSEG 345


>gi|41281808 harmonin isoform b3 [Homo sapiens]
          Length = 899

 Score = 29.6 bits (65), Expect = 6.1
 Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 23  SNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHV 82
           SN +  +    ERQ    R+ +       N R +    Q+VE++E+  ++    +G+K  
Sbjct: 327 SNKILQEQQEMERQR---RKEIAQKAAEENERYRKEMEQIVEEEEKFKKQWEEDWGSKEQ 383

Query: 83  IMLFVPVTL-CMVVVVATIKSVSFYTRKDGQ 112
           ++L   +T     V +   KS  ++ R DG+
Sbjct: 384 LLLPKTITAEVHPVPLRKPKSFGWFYRYDGK 414


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,576,321
Number of Sequences: 37866
Number of extensions: 697225
Number of successful extensions: 3276
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 3220
Number of HSP's gapped (non-prelim): 67
length of query: 467
length of database: 18,247,518
effective HSP length: 106
effective length of query: 361
effective length of database: 14,233,722
effective search space: 5138373642
effective search space used: 5138373642
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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