Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 4506153

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506153 prostasin preproprotein [Homo sapiens]
         (343 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506153 prostasin preproprotein [Homo sapiens]                     711   0.0  
gi|117956391 protease, serine, 33 [Homo sapiens]                      257   1e-68
gi|13994276 marapsin [Homo sapiens]                                   238   8e-63
gi|11545839 protease, serine, 22 [Homo sapiens]                       233   2e-61
gi|58218970 protease, serine, 36 [Homo sapiens]                       224   1e-58
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      220   1e-57
gi|21614531 testisin isoform 2 [Homo sapiens]                         215   4e-56
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         213   2e-55
gi|5803197 testisin isoform 1 [Homo sapiens]                          213   2e-55
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             207   8e-54
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            204   7e-53
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           203   2e-52
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  202   5e-52
gi|187761337 transmembrane protease, serine 11B [Homo sapiens]        199   2e-51
gi|148806900 epidermis-specific serine protease-like protein [Ho...   199   3e-51
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         196   2e-50
gi|223942069 enterokinase precursor [Homo sapiens]                    194   7e-50
gi|4503627 coagulation factor XI precursor [Homo sapiens]             194   7e-50
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]          194   1e-49
gi|33695155 hepsin [Homo sapiens]                                     194   1e-49
gi|4504481 hepsin [Homo sapiens]                                      194   1e-49
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]           193   2e-49
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   188   5e-48
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          186   3e-47
gi|34098976 marapsin 2 [Homo sapiens]                                 185   4e-47
gi|4504383 HGF activator preproprotein [Homo sapiens]                 185   6e-47
gi|11415040 matriptase [Homo sapiens]                                 183   2e-46
gi|21614533 testisin isoform 3 [Homo sapiens]                         182   5e-46
gi|222831592 transmembrane protease, serine 7 [Homo sapiens]          180   2e-45
gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo ...   179   3e-45

>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  711 bits (1835), Expect = 0.0
 Identities = 343/343 (100%), Positives = 343/343 (100%)

Query: 1   MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQV 60
           MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQV
Sbjct: 1   MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQV 60

Query: 61  SITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDI 120
           SITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDI
Sbjct: 61  SITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDI 120

Query: 121 IPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSV 180
           IPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSV
Sbjct: 121 IPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSV 180

Query: 181 SLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGG 240
           SLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGG
Sbjct: 181 SLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGG 240

Query: 241 PLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQ 300
           PLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQ
Sbjct: 241 PLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQ 300

Query: 301 PDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH 343
           PDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH
Sbjct: 301 PDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH 343


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  257 bits (656), Expect = 1e-68
 Identities = 128/275 (46%), Positives = 170/275 (61%), Gaps = 7/275 (2%)

Query: 15  VAILLYLGLLRSGTGAEGAE-APCGVAPQA-RITGGSSAVAGQWPWQVSITYEGVHVCGG 72
           V +LL LG      G +G + A CG    + RI GG     G+WPWQ SI + G HVCGG
Sbjct: 9   VLLLLVLG----AAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGG 64

Query: 73  SLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQ 132
           SL++ QWVL+AAHCFP       Y V+LGA +L S S       ++ ++  P Y ++G++
Sbjct: 65  SLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGAR 124

Query: 133 GDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLE 192
           GD+ALLQL RP+  S  ++P+CLP   A  P G  C VTGWG + P V L   +PLQ + 
Sbjct: 125 GDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVR 184

Query: 193 VPLISRETCNCLYNIDAK-PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWY 251
           VPL+   TC+ LY++ A  P+    V    +CAGY +G KDACQGDSGGPL+C   G W 
Sbjct: 185 VPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWV 244

Query: 252 LTGIVSWGDACGARNRPGVYTLASSYASWIQSKVT 286
           L G+VSWG  C   NRPGVYT  ++Y+ WIQ++V+
Sbjct: 245 LVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVS 279


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  238 bits (606), Expect = 8e-63
 Identities = 119/278 (42%), Positives = 164/278 (58%), Gaps = 5/278 (1%)

Query: 14  AVAILLYLGLLRSGTGAEGAEAPCGVAPQA-RITGGSSAVAGQWPWQVSITYEGVHVCGG 72
           AV +LL   LL  G+    A   CG      R+ GG     G+WPWQVSI   G H CGG
Sbjct: 6   AVPLLL---LLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGG 62

Query: 73  SLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQ 132
           SL++EQWVL+AAHCF +      Y+V LGA QL      A  + ++ +  +P Y    S 
Sbjct: 63  SLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASS 122

Query: 133 GDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLE 192
            D+AL++L  P+ F+ YI P+CLP  +  F  G++C VTGWG  +    L  P+ LQ+L 
Sbjct: 123 ADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLA 182

Query: 193 VPLISRETCNCLYNIDAK-PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWY 251
           VP+I    CN LY+ D +   +P  ++ DM+CAG+ EG KDAC+GDSGGPL C V   W 
Sbjct: 183 VPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWL 242

Query: 252 LTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQ 289
             G++SWG+ C  +NRPGVY   +++ +WI   + +LQ
Sbjct: 243 QAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQ 280


>gi|11545839 protease, serine, 22 [Homo sapiens]
          Length = 317

 Score =  233 bits (594), Expect = 2e-61
 Identities = 128/292 (43%), Positives = 169/292 (57%), Gaps = 13/292 (4%)

Query: 7   LGPGQLGAVAILLYLGLLRSGTGAEGAEAP----CGVAPQA-RITGGSSAVAGQWPWQVS 61
           LG G LG    LL   LL S      A  P    CG   Q  R+ GG  +   +WPW VS
Sbjct: 10  LGGGCLGTFTSLL---LLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVS 66

Query: 62  ITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKE-AYEVKLGAHQLDSYSEDAKVSTLKDI 120
           I   G H C GSL++ +WV++AAHCF    +K   + V LGA QL +    ++   +  +
Sbjct: 67  IQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWV 126

Query: 121 IPHPSYL-QEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPS 179
            PHP Y  +EG+  DIAL++L R I FS  + PICLP A+   P   HC ++GWG +   
Sbjct: 127 EPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDG 186

Query: 180 VSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSG 239
           V L  P+ LQ+L+VP+I  E C+ LY   A       + EDM+CAGY+EG +DAC GDSG
Sbjct: 187 VPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGP---ITEDMLCAGYLEGERDACLGDSG 243

Query: 240 GPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPR 291
           GPL C V+G W L GI+SWG+ C  RNRPGVY   S++ SW++  V  +Q R
Sbjct: 244 GPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLR 295


>gi|58218970 protease, serine, 36 [Homo sapiens]
          Length = 855

 Score =  224 bits (570), Expect = 1e-58
 Identities = 119/283 (42%), Positives = 160/283 (56%), Gaps = 6/283 (2%)

Query: 26  SGTGAEGAEAPCG-VAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAA 84
           S T  E  +  CG   P ARI GGS+A  G WPWQVS+ + G H+CGGSL++  WVLSAA
Sbjct: 27  SPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAA 86

Query: 85  HCFPSEHHKEA---YEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLS 141
           HCF +    E    + V LG H  D   + A    +  I+   +Y Q     D+ALL+L+
Sbjct: 87  HCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLA 146

Query: 142 RPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETC 201
            P +    + P+CLP A+  F +G  C  TGWG V  +  L  P  LQ++E+ L+   TC
Sbjct: 147 SPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATC 206

Query: 202 NCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA 261
            CLY+          +   M+CAGY EG +D CQGDSGGPL C   G W+  GI S+G  
Sbjct: 207 QCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFG 266

Query: 262 CGARNRPGVYTLASSYASWIQSKV--TELQPRVVPQTQESQPD 302
           CG RNRPGV+T  ++Y +WI+ +V  +E  P    Q Q++Q D
Sbjct: 267 CGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSD 309



 Score =  107 bits (266), Expect = 2e-23
 Identities = 88/319 (27%), Positives = 135/319 (42%), Gaps = 50/319 (15%)

Query: 37  CGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAY 96
           CG AP+           G WPW+  +   G   C G+LVSE WVL+ A CF   +  ++ 
Sbjct: 325 CGKAPRP----------GAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSP 374

Query: 97  EVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLP 156
              L A ++   S   +   +  ++ H +   + +  D+ALLQL  P+  S   RP+CLP
Sbjct: 375 PRDLDAWRVLLPSR-PRAERVARLVQHENASWDNA-SDLALLQLRTPVNLSAASRPVCLP 432

Query: 157 AANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYN-----IDAKP 211
                F  G  C +  WG   P++      P   LE  L+    C+CLY      +    
Sbjct: 433 HPEHYFLPGSRCRLARWGRGEPALG-----PGALLEAELLGGWWCHCLYGRQGAAVPLPG 487

Query: 212 EEPHFVQEDMVCAGYVEGGK-DACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGV 270
           + PH      +C  Y E  +  +C  DS   L C  EG W+L GI  +   C    RP  
Sbjct: 488 DPPH-----ALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGC---LRPRA 539

Query: 271 YTLASSYASWIQSKVTE---LQPRVV----PQTQESQPDSNLCGSHLAFSSAPAQGLLRP 323
           +    ++  WI S VT    L+ ++     P  +E+  ++  C  H    +   +    P
Sbjct: 540 FFPLQTHGPWI-SHVTRGAYLEDQLAWDWGPDGEET--ETQTCPPHTEHGACGLRLEAAP 596

Query: 324 ILFLPLGLALGLLSPWLSE 342
           +         G+L PWL+E
Sbjct: 597 V---------GVLWPWLAE 606



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 80/265 (30%), Positives = 107/265 (40%), Gaps = 34/265 (12%)

Query: 56  WPWQVSITYEGVHVCGGSLVSEQWVLSAAHCF--PSEHHKEAYEVKLGAHQLDSYSEDAK 113
           WPW   +   G  VC G L++  WVL+A HC   P        EV LG     S  +  +
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQ 660

Query: 114 VSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGW 173
           VS L   I  P +L  G +  +ALL+LS  +  S    PICL    A  P G  C V GW
Sbjct: 661 VSRLVISIRLPQHL--GLRPPLALLELSSRVEPSPSALPICLHP--AGIPPGASCWVLGW 716

Query: 174 GHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDA 233
                 V +          V ++++  C+CLY     P          +C  Y EG ++ 
Sbjct: 717 KEPQDRVPVAA-------AVSILTQRICDCLYQGILPP--------GTLCVLYAEGQENR 761

Query: 234 CQGDSGGPLSCPV-EGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTE---LQ 289
           C+  S  PL C + EG W L G+   G          ++       +WI   V E   L 
Sbjct: 762 CEMTSAPPLLCQMTEGSWILVGMAVQGSR-------ELFAAIGPEEAWISQTVGEANFLP 814

Query: 290 PRVVPQTQESQPDSNLCGSHLAFSS 314
           P   P        SNLC   LA +S
Sbjct: 815 PSGSPHWPTG--GSNLCPPELAKAS 837


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  220 bits (561), Expect = 1e-57
 Identities = 124/281 (44%), Positives = 159/281 (56%), Gaps = 19/281 (6%)

Query: 12  LGAVAILLYLGLLRSGTGAEGAEAPCGVAPQA-----RITGGSSAVAGQWPWQVSITYEG 66
           LGA  +LL L +   G      +  CG  PQ      RI GG +A AG WPWQ S+    
Sbjct: 3   LGACGLLLLLAV--PGVSLRTLQPGCG-RPQVSDAGGRIVGGHAAPAGAWPWQASLRLRR 59

Query: 67  VHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSY 126
           VHVCGGSL+S QWVL+AAHCF    +   Y+V LG  ++   +     ST++ II H S 
Sbjct: 60  VHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEI---TLSPHFSTVRQIILHSSP 116

Query: 127 L-QEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTP 185
             Q G+ GDIAL++LS P+T S  I P+CLP A+  F  G+ C VTGWG+      L  P
Sbjct: 117 SGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPP 176

Query: 186 KPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCP 245
             L++++V ++  ETC      D        +Q DM+CA    G  DACQ DSGGPL C 
Sbjct: 177 YSLREVKVSVVDTETCRR----DYPGPGGSILQPDMLCA---RGPGDACQDDSGGPLVCQ 229

Query: 246 VEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVT 286
           V G W   GIVSWG+ CG  NRPGVYT   +Y +WI+  +T
Sbjct: 230 VNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHIT 270


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  215 bits (548), Expect = 4e-56
 Identities = 137/337 (40%), Positives = 182/337 (54%), Gaps = 45/337 (13%)

Query: 16  AILLYLGLLRSGTGA-EGAEA-----PCGVAP-QARITGGSSAVAGQWPWQVSITYEGVH 68
           A+LL L L R+G    E  EA     PCG     +RI GG  A  G+WPWQ S+     H
Sbjct: 6   ALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSH 65

Query: 69  VCGGSLVSEQWVLSAAHCFPSE-HHKEAYEVKLGAHQLDSYSEDAKVST------LKDII 121
           VCG SL+S +W L+AAHCF ++      + V+ G  QL S      +        + +I 
Sbjct: 66  VCGVSLLSHRWALTAAHCFETDLSDPSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSNIY 123

Query: 122 PHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVS 181
             P YL   S  DIAL++LS P+T++++I+PICL A+   F N   C VTGWG++    +
Sbjct: 124 LSPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEA 182

Query: 182 LLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGP 241
           L +P  LQ+++V +I+   CN L+    K      +  DMVCAG  +GGKDAC GDSGGP
Sbjct: 183 LPSPHTLQEVQVAIINNSMCNHLF---LKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGP 239

Query: 242 LSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQP 301
           L+C   GLWY  G+VSWG  CG  NRPGVYT  S +  WIQ        +++ Q+  SQP
Sbjct: 240 LACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQ--------KLMAQSGMSQP 291

Query: 302 DSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSP 338
           D +                  P+LF PL  AL LL P
Sbjct: 292 DPSW-----------------PLLFFPLLWALPLLGP 311


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  213 bits (542), Expect = 2e-55
 Identities = 123/309 (39%), Positives = 173/309 (55%), Gaps = 31/309 (10%)

Query: 1   MAQKGVLGPGQLGAVAILLYLGLLRSGTGAE------GAEAPCGVAP-QARITGGSSAVA 53
           +A+ G+  PG+LGA         L++G GA       G E  CG     A + GG  +  
Sbjct: 13  LARAGLGKPGELGA---------LQAGPGAARRPGGGGREEACGHREIHALVAGGVESAR 63

Query: 54  GQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGA-------HQLD 106
           G+WPWQ S+     H CGGSL+S +WVLSAAHCF   ++   + V+LG          L 
Sbjct: 64  GRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPWNLR 123

Query: 107 SYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGL 166
           +YS   KV   +DII +P  L    + DIALL+L+  +T++ YI+PIC+ ++  +F +  
Sbjct: 124 AYSSRYKV---QDIIVNPDALGV-LRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRP 179

Query: 167 HCTVTGWGHVAPSVSLLTPK-PLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAG 225
            C VTGWG ++PS + L P   L++ +V +++   CN L+    +P     + + M CAG
Sbjct: 180 DCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFE---QPSSRSMIWDSMFCAG 236

Query: 226 YVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKV 285
             +G  D C+GDSGGPL C  +GLWY  GIVSWG  CG  NRPGVYT  S Y  WI+  +
Sbjct: 237 AEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVM 296

Query: 286 TELQPRVVP 294
           +   PR  P
Sbjct: 297 SHSTPRPNP 305


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  213 bits (542), Expect = 2e-55
 Identities = 137/339 (40%), Positives = 181/339 (53%), Gaps = 47/339 (13%)

Query: 16  AILLYLGLLRSGTGA-EGAEA-----PCGVAP-QARITGGSSAVAGQWPWQVSITYEGVH 68
           A+LL L L R+G    E  EA     PCG     +RI GG  A  G+WPWQ S+     H
Sbjct: 6   ALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSH 65

Query: 69  VCGGSLVSEQWVLSAAHCFPSEHH---KEAYEVKLGAHQLDSYSEDAKVST------LKD 119
           VCG SL+S +W L+AAHCF +         + V+ G  QL S      +        + +
Sbjct: 66  VCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSN 123

Query: 120 IIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPS 179
           I   P YL   S  DIAL++LS P+T++++I+PICL A+   F N   C VTGWG++   
Sbjct: 124 IYLSPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED 182

Query: 180 VSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSG 239
            +L +P  LQ+++V +I+   CN L+    K      +  DMVCAG  +GGKDAC GDSG
Sbjct: 183 EALPSPHTLQEVQVAIINNSMCNHLF---LKYSFRKDIFGDMVCAGNAQGGKDACFGDSG 239

Query: 240 GPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQES 299
           GPL+C   GLWY  G+VSWG  CG  NRPGVYT  S +  WIQ        +++ Q+  S
Sbjct: 240 GPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQ--------KLMAQSGMS 291

Query: 300 QPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSP 338
           QPD +                  P+LF PL  AL LL P
Sbjct: 292 QPDPSW-----------------PLLFFPLLWALPLLGP 313


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  207 bits (528), Expect = 8e-54
 Identities = 101/256 (39%), Positives = 145/256 (56%), Gaps = 12/256 (4%)

Query: 32  GAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGV---HVCGGSLVSEQWVLSAAHCFP 88
           G  + C      RI GG+++  G+WPWQVS+  +     H+CGGSL+  QWVL+AAHCF 
Sbjct: 378 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD 437

Query: 89  SEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSR 148
               ++ + +  G   L   ++D   S +K+II H +Y       DIAL++L  P+ ++ 
Sbjct: 438 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTE 497

Query: 149 YIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNID 208
           + +PICLP+   +     +C VTGWG       +     LQ++ +PL++ E C   Y   
Sbjct: 498 FQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI--QNILQKVNIPLVTNEECQKRY--- 552

Query: 209 AKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRP 268
               + + + + MVCAGY EGGKDAC+GDSGGPL C   G+W L GI SWG+ C  R +P
Sbjct: 553 ----QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQP 608

Query: 269 GVYTLASSYASWIQSK 284
           GVYT  + Y  WI  K
Sbjct: 609 GVYTKVAEYMDWILEK 624


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  204 bits (520), Expect = 7e-53
 Identities = 111/273 (40%), Positives = 151/273 (55%), Gaps = 10/273 (3%)

Query: 18  LLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEG---VHVCGGSL 74
           LL L L    + A  A AP     +  I GG  A   +WPWQVS+   G   +H CGGSL
Sbjct: 4   LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSL 63

Query: 75  VSEQWVLSAAHCF-PSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQG 133
           +  QWVL+AAHC  P      A  V+L    L  Y +D ++  +  II HP +       
Sbjct: 64  IHPQWVLTAAHCVGPDVKDLAALRVQLREQHL--YYQD-QLLPVSRIIVHPQFYTAQIGA 120

Query: 134 DIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEV 193
           DIALL+L  P+  S ++  + LP A+ +FP G+ C VTGWG V     L  P PL+Q++V
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180

Query: 194 PLISRETCNCLYNIDA-KPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYL 252
           P++    C+  Y++ A   ++   V++DM+CAG     +D+CQGDSGGPL C V G W  
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQ 238

Query: 253 TGIVSWGDACGARNRPGVYTLASSYASWIQSKV 285
            G+VSWG+ C   NRPG+YT  + Y  WI   V
Sbjct: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  203 bits (516), Expect = 2e-52
 Identities = 104/262 (39%), Positives = 150/262 (57%), Gaps = 14/262 (5%)

Query: 29  GAEGAEAPCGV-APQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCF 87
           G++     CG+  P +RI GG+ +  G+WPWQ S+   G H+CGG+L++++WV++AAHCF
Sbjct: 560 GSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCF 619

Query: 88  PSEHHKEA--YEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPIT 145
             +       + V LG    +S         +  ++ HP + ++    D+ALLQL  P+ 
Sbjct: 620 QEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVV 679

Query: 146 FSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLY 205
            S  +RP+CLPA +  F  GLHC +TGWG +     +     LQ+++V LI ++ C+ +Y
Sbjct: 680 RSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPI--SNALQKVDVQLIPQDLCSEVY 737

Query: 206 NIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGA 264
                P         M+CAGY +G KDACQGDSGGPL C  + G W+L G+VSWG  CG 
Sbjct: 738 RYQVTPR--------MLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGR 789

Query: 265 RNRPGVYTLASSYASWIQSKVT 286
            N  GVYT  +   SWIQ  VT
Sbjct: 790 PNYFGVYTRITGVISWIQQVVT 811


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  202 bits (513), Expect = 5e-52
 Identities = 110/273 (40%), Positives = 150/273 (54%), Gaps = 10/273 (3%)

Query: 18  LLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEG---VHVCGGSL 74
           LL L L    + A  A AP     +  I GG  A   +WPWQVS+       +H CGGSL
Sbjct: 4   LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSL 63

Query: 75  VSEQWVLSAAHCF-PSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQG 133
           +  QWVL+AAHC  P      A  V+L    L  Y +D ++  +  II HP +       
Sbjct: 64  IHPQWVLTAAHCVGPDVKDLAALRVQLREQHL--YYQD-QLLPVSRIIVHPQFYTAQIGA 120

Query: 134 DIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEV 193
           DIALL+L  P+  S ++  + LP A+ +FP G+ C VTGWG V     L  P PL+Q++V
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180

Query: 194 PLISRETCNCLYNIDA-KPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYL 252
           P++    C+  Y++ A   ++   V++DM+CAG     +D+CQGDSGGPL C V G W  
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQ 238

Query: 253 TGIVSWGDACGARNRPGVYTLASSYASWIQSKV 285
            G+VSWG+ C   NRPG+YT  + Y  WI   V
Sbjct: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271


>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
          Length = 416

 Score =  199 bits (507), Expect = 2e-51
 Identities = 101/242 (41%), Positives = 142/242 (58%), Gaps = 13/242 (5%)

Query: 44  RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAH 103
           +I  G S++ G WPWQ S+ ++G H CG SL+S +W+LSAAHCF  +++ + + V  G  
Sbjct: 184 KIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIV 243

Query: 104 QLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFP 163
               Y        +++II H +Y   G   DIAL+QL+  ++F+ YIR ICLP A     
Sbjct: 244 VNKPY----MTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLS 299

Query: 164 NGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVC 223
              +  VTGWG +  + S   P  LQ+  + +I  + CN  Y          FV + M+C
Sbjct: 300 ENDNVVVTGWGTLYMNGSF--PVILQEDFLKIIDNKICNASYAYSG------FVTDTMLC 351

Query: 224 AGYVEGGKDACQGDSGGPLSCP-VEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQ 282
           AG++ G  DACQ DSGGPL+ P    +W+L GIVSWGD CG +N+PGVYT  +SY +WI 
Sbjct: 352 AGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWIT 411

Query: 283 SK 284
           SK
Sbjct: 412 SK 413


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  199 bits (506), Expect = 3e-51
 Identities = 106/247 (42%), Positives = 146/247 (59%), Gaps = 8/247 (3%)

Query: 43  ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGA 102
           +R+ GG  A AG+WPWQVS+ ++   +CGGSLVSE+ +L+AAHC        +Y V LG+
Sbjct: 26  SRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFSYTVWLGS 85

Query: 103 HQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASF 162
             +    +  K    K +I HP Y  + +  D+ALL+LS  +TF+  I PICLP+     
Sbjct: 86  ITVGDSRKRVKYYVSKIVI-HPKY--QDTTADVALLKLSSQVTFTSAILPICLPSVTKQL 142

Query: 163 PNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYN---IDAKPEEPHFVQE 219
                C VTGWG V  S        LQ+ EVP+I R+ C  LYN   I     EP  ++E
Sbjct: 143 AIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIGIFLPALEP-VIKE 201

Query: 220 DMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYAS 279
           D +CAG  +  KD+C+GDSGGPLSC ++G+W  TG+VSWG  CG ++ PGVYT    Y  
Sbjct: 202 DKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECG-KSLPGVYTNVIYYQK 260

Query: 280 WIQSKVT 286
           WI + ++
Sbjct: 261 WINATIS 267


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  196 bits (499), Expect = 2e-50
 Identities = 103/252 (40%), Positives = 145/252 (57%), Gaps = 13/252 (5%)

Query: 37  CGV-APQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHK-- 93
           CG+ A   RI GG+ A   +WPWQVS+ +   H+CGG+L+  QWVL+AAHCF     K  
Sbjct: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376

Query: 94  EAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPI 153
           E ++V  G   L    E A ++   +II + +Y  E    DIAL++LS+P+T S +I P 
Sbjct: 377 EGWKVYAGTSNLHQLPEAASIA---EIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433

Query: 154 CLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEE 213
           CLP    +F     C +TG+G    +    +P  L++++V LI  + CN     D+    
Sbjct: 434 CLPMHGQTFSLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLVYDS---- 488

Query: 214 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTL 273
             ++   M+CAG + GG+D+CQGDSGGPL C     WYL G+ SWG  CG RN+PGVYT 
Sbjct: 489 --YLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTK 546

Query: 274 ASSYASWIQSKV 285
            +    WI SK+
Sbjct: 547 VTEVLPWIYSKM 558


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score =  194 bits (494), Expect = 7e-50
 Identities = 101/242 (41%), Positives = 138/242 (57%), Gaps = 11/242 (4%)

Query: 44   RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEA-YEVKLGA 102
            +I GGS+A  G WPW V + Y G  +CG SLVS  W++SAAHC    + + + +   LG 
Sbjct: 784  KIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGL 843

Query: 103  HQLDSYSEDAKVSTLKD-IIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANAS 161
            H   + +    V  L D I+ +P Y +     DIA++ L   + ++ YI+PICLP  N  
Sbjct: 844  HMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQV 903

Query: 162  FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDM 221
            FP G +C++ GWG V    +  T   LQ+ +VPL+S E C         PE  + + E+M
Sbjct: 904  FPPGRNCSIAGWGTVVYQGT--TANILQEADVPLLSNERCQ-----QQMPE--YNITENM 954

Query: 222  VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 281
            +CAGY EGG D+CQGDSGGPL C     W+L G+ S+G  C   NRPGVY   S +  WI
Sbjct: 955  ICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI 1014

Query: 282  QS 283
            QS
Sbjct: 1015 QS 1016


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  194 bits (494), Expect = 7e-50
 Identities = 100/251 (39%), Positives = 134/251 (53%), Gaps = 12/251 (4%)

Query: 37  CGVAPQARITGGSSAVAGQWPWQVSITYEGV---HVCGGSLVSEQWVLSAAHCFPSEHHK 93
           C    + RI GG+++V G+WPWQV++        H+CGGS++  QW+L+AAHCF      
Sbjct: 380 CTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESP 439

Query: 94  EAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPI 153
           +   V  G        ED     +++II H  Y    S  DIALL+L   + ++   RPI
Sbjct: 440 KILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPI 499

Query: 154 CLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEE 213
           CLP+          C VTGWG+      +     LQ+ ++PL++ E C   Y        
Sbjct: 500 CLPSKGDRNVIYTDCWVTGWGYRKLRDKI--QNTLQKAKIPLVTNEECQKRYR------- 550

Query: 214 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTL 273
            H +   M+CAGY EGGKDAC+GDSGGPLSC    +W+L GI SWG+ C  R RPGVYT 
Sbjct: 551 GHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTN 610

Query: 274 ASSYASWIQSK 284
              Y  WI  K
Sbjct: 611 VVEYVDWILEK 621


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score =  194 bits (493), Expect = 1e-49
 Identities = 102/249 (40%), Positives = 135/249 (54%), Gaps = 13/249 (5%)

Query: 37  CGVAPQA-RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEA 95
           CG  P A RI GG S   G+WPWQ S+     H CGGS+++ +WV++AAHC  S      
Sbjct: 209 CGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARL 268

Query: 96  YEVKLGAHQLD-SYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPIC 154
              ++ A  +  S     + + ++ IIPHP Y  +    D+ALL+L   + FS  +  +C
Sbjct: 269 SSWRVHAGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVC 328

Query: 155 LPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCN--CLYNIDAKPE 212
           LPA    FP G  C V+GWGH  PS +  +   LQ   VPL S + CN  C+Y+    P 
Sbjct: 329 LPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDM-LQDTVVPLFSTQLCNSSCVYSGALTPR 387

Query: 213 EPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYT 272
                   M+CAGY++G  DACQGDSGGPL CP    W L G+VSWG  C   N PGVY 
Sbjct: 388 --------MLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYA 439

Query: 273 LASSYASWI 281
             + +  WI
Sbjct: 440 KVAEFLDWI 448


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  194 bits (492), Expect = 1e-49
 Identities = 107/253 (42%), Positives = 137/253 (54%), Gaps = 23/253 (9%)

Query: 41  PQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 100
           P  RI GG     G+WPWQVS+ Y+G H+CGGSL+S  WVL+AAHCFP E ++     ++
Sbjct: 159 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFP-ERNRVLSRWRV 217

Query: 101 GAHQLDSYSEDAKVSTLKDIIPHPSYL------QEGSQGDIALLQLSRPITFSRYIRPIC 154
            A  +   S       ++ ++ H  YL       E +  DIAL+ LS P+  + YI+P+C
Sbjct: 218 FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 277

Query: 155 LPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCN--CLYNIDAKPE 212
           LPAA  +  +G  CTVTGWG+            LQ+  VP+IS + CN    Y    KP+
Sbjct: 278 LPAAGQALVDGKICTVTGWGNT--QYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPK 335

Query: 213 EPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVE----GLWYLTGIVSWGDACGARNRP 268
                   M CAGY EGG DACQGDSGGP  C         W L GIVSWG  C    +P
Sbjct: 336 --------MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKP 387

Query: 269 GVYTLASSYASWI 281
           GVYT  S +  WI
Sbjct: 388 GVYTKVSDFREWI 400


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  194 bits (492), Expect = 1e-49
 Identities = 107/253 (42%), Positives = 137/253 (54%), Gaps = 23/253 (9%)

Query: 41  PQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 100
           P  RI GG     G+WPWQVS+ Y+G H+CGGSL+S  WVL+AAHCFP E ++     ++
Sbjct: 159 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFP-ERNRVLSRWRV 217

Query: 101 GAHQLDSYSEDAKVSTLKDIIPHPSYL------QEGSQGDIALLQLSRPITFSRYIRPIC 154
            A  +   S       ++ ++ H  YL       E +  DIAL+ LS P+  + YI+P+C
Sbjct: 218 FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 277

Query: 155 LPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCN--CLYNIDAKPE 212
           LPAA  +  +G  CTVTGWG+            LQ+  VP+IS + CN    Y    KP+
Sbjct: 278 LPAAGQALVDGKICTVTGWGNT--QYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPK 335

Query: 213 EPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVE----GLWYLTGIVSWGDACGARNRP 268
                   M CAGY EGG DACQGDSGGP  C         W L GIVSWG  C    +P
Sbjct: 336 --------MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKP 387

Query: 269 GVYTLASSYASWI 281
           GVYT  S +  WI
Sbjct: 388 GVYTKVSDFREWI 400


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score =  193 bits (491), Expect = 2e-49
 Identities = 98/271 (36%), Positives = 145/271 (53%), Gaps = 14/271 (5%)

Query: 29  GAEGAEAPCGVAPQ----ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAA 84
           G++ A   CG+ P      RI GG  A  G++PWQ S+     H CG ++++ +W++SAA
Sbjct: 183 GSDEAHCECGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAA 242

Query: 85  HCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPI 144
           HCF        +   +GA  L         + +  I+ HP Y  + +  D+A+L+L+ P+
Sbjct: 243 HCFNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPL 302

Query: 145 TFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCL 204
            F R+I+P+CLPAA   FP    C ++GWG++     L+ P+ LQ+  V L+ +  C  L
Sbjct: 303 PFGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDF-LVKPEVLQKATVELLDQALCASL 361

Query: 205 YNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACG 263
           Y         H + + MVCAGY++G  D+CQGDSGGPL C    G ++L GIVSWG  C 
Sbjct: 362 YG--------HSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCA 413

Query: 264 ARNRPGVYTLASSYASWIQSKVTELQPRVVP 294
              RPGVY   +    WI    T+    + P
Sbjct: 414 EARRPGVYARVTRLRDWILEATTKASMPLAP 444



 Score =  189 bits (480), Expect = 3e-48
 Identities = 104/255 (40%), Positives = 141/255 (55%), Gaps = 16/255 (6%)

Query: 37   CGVAPQA--RITGGSSAVAGQWPWQVSITYEG-VHVCGGSLVSEQWVLSAAHCFPSEHHK 93
            CG+AP A  RI GGS+A  G+WPWQVS+      H CG  LV+E+W+LSAAHCF      
Sbjct: 817  CGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDP 876

Query: 94   EAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPI 153
            + +   LG   L     + ++  +  I  HP Y       D+ALL+L+ P+  SR +RPI
Sbjct: 877  KQWAAFLGTPFLSG--AEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPI 934

Query: 154  CLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEE 213
            CLP      P+G  C +TGWG V    S+   + LQ+  V L+S +TC   Y        
Sbjct: 935  CLPEPAPRPPDGTRCVITGWGSVREGGSM--ARQLQKAAVRLLSEQTCRRFY-------- 984

Query: 214  PHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGARNRPGVYT 272
            P  +   M+CAG+ +GG D+C GD+GGPL+C    G W LTG+ SWG  CG  + PGVYT
Sbjct: 985  PVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYT 1044

Query: 273  LASSYASWIQSKVTE 287
              ++   WI   + E
Sbjct: 1045 RVAAVRGWIGQHIQE 1059



 Score =  188 bits (478), Expect = 5e-48
 Identities = 98/252 (38%), Positives = 144/252 (57%), Gaps = 19/252 (7%)

Query: 37  CGVAPQ----ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHH 92
           CG  P      R+ GG  A +G+ PWQVS+     H CG ++V ++W+LSAAHCF   +H
Sbjct: 492 CGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCF---NH 548

Query: 93  KEAYEVK--LGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYI 150
            +  +V+  LG   L           L+ ++ HP Y       D+A+L+L+ P+ F++YI
Sbjct: 549 TKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYI 608

Query: 151 RPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAK 210
           +P+CLP A   FP G  C ++GWG+     +   P+ LQ+  V +I ++TC+ LYN    
Sbjct: 609 QPVCLPLAIQKFPVGRKCMISGWGNTQEG-NATKPELLQKASVGIIDQKTCSVLYNFS-- 665

Query: 211 PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGARNRPG 269
                 + + M+CAG++EG  D+CQGDSGGPL+C    G++YL GIVSWG  C    +PG
Sbjct: 666 ------LTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPG 719

Query: 270 VYTLASSYASWI 281
           VYT  +    WI
Sbjct: 720 VYTRITRLKGWI 731


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  188 bits (478), Expect = 5e-48
 Identities = 90/243 (37%), Positives = 139/243 (57%), Gaps = 9/243 (3%)

Query: 43  ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGA 102
           +RI GG+ ++  QWPWQ S+ ++G H+CGGS+++  W+++AAHC    +  +++ +++G 
Sbjct: 215 SRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGL 274

Query: 103 HQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASF 162
             L      A    ++ I+ H  Y  +    DIAL++L+ P+TF+  I+P+CLP +  +F
Sbjct: 275 VSL--LDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENF 332

Query: 163 PNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMV 222
           P+G  C  +GWG         +P  L    VPLIS + CN       +      +   M+
Sbjct: 333 PDGKVCWTSGWGATEDGAGDASPV-LNHAAVPLISNKICN------HRDVYGGIISPSML 385

Query: 223 CAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQ 282
           CAGY+ GG D+CQGDSGGPL C    LW L G  S+G  C   N+PGVYT  +S+  WI 
Sbjct: 386 CAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIH 445

Query: 283 SKV 285
            ++
Sbjct: 446 EQM 448


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  186 bits (471), Expect = 3e-47
 Identities = 99/255 (38%), Positives = 141/255 (55%), Gaps = 19/255 (7%)

Query: 37  CGVAP------QARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSE 90
           CG  P      + RI GG+ A  G WPWQVS+     H CGGSL++  W+L+AAHCF S 
Sbjct: 173 CGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN 232

Query: 91  HHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYI 150
            +   +    G     S +       +++I+ H +Y     + DIAL++L   +TF++ I
Sbjct: 233 SNPRDWIATSGI----STTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDI 288

Query: 151 RPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAK 210
             +CLPAA  + P G    VTGWG  A   +  T   L+Q +V +IS + CN  ++ +  
Sbjct: 289 HSVCLPAATQNIPPGSTAYVTGWG--AQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGA 346

Query: 211 PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPL-SCPVEGLWYLTGIVSWGDACGARNRPG 269
                 +   M+CAG  +GG DACQGDSGGPL       LW++ GIVSWGD CG  ++PG
Sbjct: 347 ------ILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPG 400

Query: 270 VYTLASSYASWIQSK 284
           VYT  ++Y  WI+ +
Sbjct: 401 VYTRVTAYLDWIRQQ 415


>gi|34098976 marapsin 2 [Homo sapiens]
          Length = 326

 Score =  185 bits (470), Expect = 4e-47
 Identities = 106/298 (35%), Positives = 152/298 (51%), Gaps = 22/298 (7%)

Query: 5   GVLGPGQLGAVAILLYLGLLR-----------SGTGAEGAEAPCGVAPQARITGGSSAVA 53
           G LGP  LG + +LL +   R            G    G+ A    + + +I GG  A  
Sbjct: 9   GPLGPSALGLLLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPE 68

Query: 54  GQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAK 113
            +WPWQVS+ Y G+HVCGGS+++E WVLSAAHCF  + + + Y++ +G   L       +
Sbjct: 69  RKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQ 128

Query: 114 VSTLKDIIPHPSY-LQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTG 172
              +  +I HP+Y +     GD+AL+QL   I FS  + P+CL     +  +  +C  TG
Sbjct: 129 WYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTSA-NCWATG 187

Query: 173 WGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKD 232
           WG V+      T   LQ++++PLI    C+ LY          ++  DM+CAG +   K 
Sbjct: 188 WGLVSKQGE--TSDELQEMQLPLILEPWCHLLYG------HMSYIMPDMLCAGDILNAKT 239

Query: 233 ACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQP 290
            C+GDSGGPL C     W   GIVSWG  C     PGVY   S ++ WI   + E+ P
Sbjct: 240 VCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNI-EITP 296


>gi|4504383 HGF activator preproprotein [Homo sapiens]
          Length = 655

 Score =  185 bits (469), Expect = 6e-47
 Identities = 100/258 (38%), Positives = 147/258 (56%), Gaps = 17/258 (6%)

Query: 44  RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAH 103
           RI GGSS++ G  PW  +I Y G   C GSLV   WV+SAAHCF     +++  V LG H
Sbjct: 407 RIIGGSSSLPGSHPWLAAI-YIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 465

Query: 104 QLDSYSEDAKVSTLKDIIPHPSY-LQEGSQGDIALLQLS----RPITFSRYIRPICLPAA 158
             +  ++  +   ++  IP+  Y +   S  D+ L++L     R  T S++++PICLP  
Sbjct: 466 FFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEP 525

Query: 159 NASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNC--LYNIDAKPEEPHF 216
            ++FP G  C + GWGH+  +VS  +   L++  VPL++   C+   +Y  D  P     
Sbjct: 526 GSTFPAGHKCQIAGWGHLDENVSGYSSS-LREALVPLVADHKCSSPEVYGADISP----- 579

Query: 217 VQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASS 276
              +M+CAGY +   DACQGDSGGPL+C   G+ YL GI+SWGD CG  ++PGVYT  ++
Sbjct: 580 ---NMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVAN 636

Query: 277 YASWIQSKVTELQPRVVP 294
           Y  WI  ++   +  V P
Sbjct: 637 YVDWINDRIRPPRRLVAP 654


>gi|11415040 matriptase [Homo sapiens]
          Length = 855

 Score =  183 bits (464), Expect = 2e-46
 Identities = 105/267 (39%), Positives = 147/267 (55%), Gaps = 25/267 (9%)

Query: 29  GAEGAEAPCGVAP---QARITGGSSAVAGQWPWQVSITYEGV-HVCGGSLVSEQWVLSAA 84
           G++  +  CG+     QAR+ GG+ A  G+WPWQVS+   G  H+CG SL+S  W++SAA
Sbjct: 596 GSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAA 655

Query: 85  HCFPSEH-----HKEAYEVKLGAH-QLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALL 138
           HC+  +          +   LG H Q    +   +   LK II HP +       DIALL
Sbjct: 656 HCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALL 715

Query: 139 QLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHV--APSVSLLTPKPLQQLEVPLI 196
           +L +P  +S  +RPICLP A+  FP G    VTGWGH     + +L+    LQ+ E+ +I
Sbjct: 716 ELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALI----LQKGEIRVI 771

Query: 197 SRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPL-SCPVEGLWYLTGI 255
           ++ TC  L         P  +   M+C G++ GG D+CQGDSGGPL S   +G  +  G+
Sbjct: 772 NQTTCENLL--------PQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGV 823

Query: 256 VSWGDACGARNRPGVYTLASSYASWIQ 282
           VSWGD C  RN+PGVYT    +  WI+
Sbjct: 824 VSWGDGCAQRNKPGVYTRLPLFRDWIK 850


>gi|21614533 testisin isoform 3 [Homo sapiens]
          Length = 300

 Score =  182 bits (461), Expect = 5e-46
 Identities = 127/339 (37%), Positives = 170/339 (50%), Gaps = 61/339 (17%)

Query: 16  AILLYLGLLRSGTGA-EGAEA-----PCGVAP-QARITGGSSAVAGQWPWQVSITYEGVH 68
           A+LL L L R+G    E  EA     PCG     +RI GG  A  G+WPWQ S+     H
Sbjct: 6   ALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSH 65

Query: 69  VCGGSLVSEQWVLSAAHCFPSEHH---KEAYEVKLGAHQLDSYSEDAKVST------LKD 119
           VCG SL+S +W L+AAHCF +         + V+ G  QL S      +        + +
Sbjct: 66  VCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSN 123

Query: 120 IIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPS 179
           I   P YL   S  DIAL++LS P+T++++I+PICL A+   F N   C VTGWG++   
Sbjct: 124 IYLSPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED 182

Query: 180 VSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSG 239
            +L +P  LQ+++V +I+   CN L+    K      +  DM              GDSG
Sbjct: 183 EALPSPHTLQEVQVAIINNSMCNHLF---LKYSFRKDIFGDM--------------GDSG 225

Query: 240 GPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQES 299
           GPL+C   GLWY  G+VSWG  CG  NRPGVYT  S +  WIQ        +++ Q+  S
Sbjct: 226 GPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQ--------KLMAQSGMS 277

Query: 300 QPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSP 338
           QPD +                  P+LF PL  AL LL P
Sbjct: 278 QPDPSW-----------------PLLFFPLLWALPLLGP 299


>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
          Length = 717

 Score =  180 bits (456), Expect = 2e-45
 Identities = 111/270 (41%), Positives = 142/270 (52%), Gaps = 23/270 (8%)

Query: 27  GTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHC 86
           G+  EG       +   RI GG+  + G WPWQVS+ + G   CG S++S +W+LSAAHC
Sbjct: 462 GSDEEGCTCSRSSSALHRIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHC 521

Query: 87  FPSEHHKEAYEVKLGAHQLDSYSE-DAK-VSTLKDIIPHPSYLQEGSQGDIALLQLS--R 142
           F   H     +       L  Y + +AK VS ++ I+ H  Y  +    DIALLQLS   
Sbjct: 522 F---HGNRLSDPTPWTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAW 578

Query: 143 PITFSRYIRPICLPAANASFPNGLHCTVTGWG--HVAPSVSLLTPKPLQQLEVPLISRET 200
           P T  + I+PIC+P       +G  C VTGWG  H A +   L    LQQ EV LI +  
Sbjct: 579 PETLKQLIQPICIPPTGQRVRSGEKCWVTGWGRRHEADNKGSLV---LQQAEVELIDQTL 635

Query: 201 CNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC--PVEGLWYLTGIVSW 258
           C   Y I         +   M+CAG + G +DAC+GDSGGPLSC    +G W LTGIVSW
Sbjct: 636 CVSTYGI---------ITSRMLCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSW 686

Query: 259 GDACGARNRPGVYTLASSYASWIQSKVTEL 288
           G   G  N PGVYT  S++  WI   V  L
Sbjct: 687 GHGSGRPNFPGVYTRVSNFVPWIHKYVPSL 716


>gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo
           sapiens]
          Length = 418

 Score =  179 bits (454), Expect = 3e-45
 Identities = 105/268 (39%), Positives = 144/268 (53%), Gaps = 21/268 (7%)

Query: 24  LRSGTGAEGAEAPCG--VAPQA--RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQW 79
           + S TG    +A CG  V P    RI  G  A    WPWQ S+ Y+ +H CG +L+S  W
Sbjct: 162 MSSSTGELTVQASCGKRVVPLNVNRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTW 221

Query: 80  VLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQ 139
           +++AAHCF    +   + V  G       +       ++  I H  Y     + DIA++Q
Sbjct: 222 LVTAAHCFQKYKNPHQWTVSFGT----KINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQ 277

Query: 140 LSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRE 199
           +S  +TFS  IR ICLP A+ASF   L   +TG+G  A      +   L++  V +IS +
Sbjct: 278 VSSRVTFSDDIRQICLPEASASFQPNLTVHITGFG--ALYYGGESQNDLREARVKIISDD 335

Query: 200 TCN--CLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPL-SCPVEGLWYLTGIV 256
            C    +Y  D KP         M CAGY+EG  DAC+GDSGGPL +  ++  WYL GIV
Sbjct: 336 VCKQPQVYGNDIKP--------GMFCAGYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIV 387

Query: 257 SWGDACGARNRPGVYTLASSYASWIQSK 284
           SWGD CG +++PGVYT  + Y +WI SK
Sbjct: 388 SWGDNCGQKDKPGVYTQVTYYRNWIASK 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,175,724
Number of Sequences: 37866
Number of extensions: 758773
Number of successful extensions: 2502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1816
Number of HSP's gapped (non-prelim): 209
length of query: 343
length of database: 18,247,518
effective HSP length: 103
effective length of query: 240
effective length of database: 14,347,320
effective search space: 3443356800
effective search space used: 3443356800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press