BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4505999 protein phosphatase 1G [Homo sapiens] (546 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4505999 protein phosphatase 1G [Homo sapiens] 1100 0.0 gi|29826282 protein phosphatase 1G [Homo sapiens] 1100 0.0 gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens] 134 2e-31 gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens] 130 2e-30 gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens] 130 2e-30 gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens] 128 2e-29 gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens] 128 2e-29 gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens] 128 2e-29 gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens] 126 4e-29 gi|122937199 protein phosphatase 1B-like [Homo sapiens] 114 3e-25 gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens] 100 3e-21 gi|7661862 protein phosphatase 1F [Homo sapiens] 92 2e-18 gi|30089948 protein phosphatase 1E [Homo sapiens] 91 4e-18 gi|13540531 integrin-linked kinase-associated protein phosphatas... 89 1e-17 gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho... 84 4e-16 gi|4505997 protein phosphatase 1D [Homo sapiens] 70 6e-12 gi|4503257 death-domain associated protein isoform a [Homo sapiens] 66 9e-11 gi|215422388 death-domain associated protein isoform a [Homo sap... 66 9e-11 gi|215422366 death-domain associated protein isoform b [Homo sap... 66 9e-11 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 65 2e-10 gi|17975763 myelin transcription factor 1 [Homo sapiens] 64 3e-10 gi|115529449 upstream binding transcription factor, RNA polymera... 64 3e-10 gi|115529451 upstream binding transcription factor, RNA polymera... 64 3e-10 gi|7657671 upstream binding transcription factor, RNA polymerase... 64 3e-10 gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo... 62 2e-09 gi|38788260 bromodomain PHD finger transcription factor isoform ... 62 2e-09 gi|38788274 bromodomain PHD finger transcription factor isoform ... 62 2e-09 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 62 2e-09 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 62 2e-09 gi|55956788 nucleolin [Homo sapiens] 60 4e-09 >gi|4505999 protein phosphatase 1G [Homo sapiens] Length = 546 Score = 1100 bits (2845), Expect = 0.0 Identities = 546/546 (100%), Positives = 546/546 (100%) Query: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYD 60 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYD Sbjct: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYD 60 Query: 61 GHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGR 120 GHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGR Sbjct: 61 GHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGR 120 Query: 121 PTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEE 180 PTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEE Sbjct: 121 PTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEE 180 Query: 181 PGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPS 240 PGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPS Sbjct: 181 PGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPS 240 Query: 241 CSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEE 300 CSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEE Sbjct: 241 CSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEE 300 Query: 301 AEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKAL 360 AEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKAL Sbjct: 301 AEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKAL 360 Query: 361 DMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISA 420 DMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISA Sbjct: 361 DMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISA 420 Query: 421 LPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELL 480 LPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELL Sbjct: 421 LPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELL 480 Query: 481 DQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKK 540 DQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKK Sbjct: 481 DQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKK 540 Query: 541 KKAKRD 546 KKAKRD Sbjct: 541 KKAKRD 546 >gi|29826282 protein phosphatase 1G [Homo sapiens] Length = 546 Score = 1100 bits (2845), Expect = 0.0 Identities = 546/546 (100%), Positives = 546/546 (100%) Query: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYD 60 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYD Sbjct: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYD 60 Query: 61 GHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGR 120 GHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGR Sbjct: 61 GHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGR 120 Query: 121 PTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEE 180 PTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEE Sbjct: 121 PTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEE 180 Query: 181 PGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPS 240 PGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPS Sbjct: 181 PGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPS 240 Query: 241 CSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEE 300 CSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEE Sbjct: 241 CSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEE 300 Query: 301 AEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKAL 360 AEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKAL Sbjct: 301 AEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKAL 360 Query: 361 DMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISA 420 DMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISA Sbjct: 361 DMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISA 420 Query: 421 LPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELL 480 LPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELL Sbjct: 421 LPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELL 480 Query: 481 DQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKK 540 DQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKK Sbjct: 481 DQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKK 540 Query: 541 KKAKRD 546 KKAKRD Sbjct: 541 KKAKRD 546 >gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens] Length = 324 Score = 134 bits (337), Expect = 2e-31 Identities = 86/235 (36%), Positives = 131/235 (55%), Gaps = 18/235 (7%) Query: 307 EEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDH 366 E +E M V M K+ SG+TAV LI + N GDSR ++ K + DH Sbjct: 107 EIDEHMRV--MSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDH 164 Query: 367 KPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKV 426 KP + +E RI+NAGG V M RVNG L +SRA+GD YK P EQ++S P++ Sbjct: 165 KPSNPLEKERIQNAGGSV-MIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHD 223 Query: 427 LTLT-DDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLA 485 + + +D +F+++ACDGIW+VM ++E+ DF++S++ D+ L + E++D CL Sbjct: 224 IERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDD------LEKVCNEVVDTCLY 277 Query: 486 PDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKK 540 + DNM+ I+ICF N ++ PE+ K++ E E E G+ +KK Sbjct: 278 KGSR------DNMSVILICFP--NAPKVSPEAVKKEAELDKYLECRVEGGSFNKK 324 Score = 75.9 bits (185), Expect = 9e-14 Identities = 47/129 (36%), Positives = 65/129 (50%), Gaps = 13/129 (10%) Query: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDS---ETAMFS 57 MGA+L +P K + G G L YG S+MQGWRV MEDAH + L S + F+ Sbjct: 1 MGAFLDKPKMEKHNAQGQGNG---LRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFA 57 Query: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYKEG-------KLQKALEDAFLAIDAKLTTEEV 110 VYDGH G +VA YC ++L D I + + +K ++ + FL ID + Sbjct: 58 VYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSE 117 Query: 111 IKELAQIAG 119 K A +G Sbjct: 118 KKHGADRSG 126 >gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens] Length = 382 Score = 130 bits (328), Expect = 2e-30 Identities = 81/218 (37%), Positives = 124/218 (56%), Gaps = 18/218 (8%) Query: 307 EEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDH 366 E +E M V M K+ SG+TAV LI + N GDSR ++ K + DH Sbjct: 107 EIDEHMRV--MSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDH 164 Query: 367 KPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKV 426 KP + +E RI+NAGG V M RVNG L +SRA+GD YK P EQ++S P++ Sbjct: 165 KPSNPLEKERIQNAGGSV-MIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHD 223 Query: 427 LTLT-DDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLA 485 + + +D +F+++ACDGIW+VM ++E+ DF++S++ D+ L + E++D CL Sbjct: 224 IERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDD------LEKVCNEVVDTCLY 277 Query: 486 PDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLE 523 + DNM+ I+ICF N ++ PE+ K++ E Sbjct: 278 KGSR------DNMSVILICFP--NAPKVSPEAVKKEAE 307 Score = 75.9 bits (185), Expect = 9e-14 Identities = 47/129 (36%), Positives = 65/129 (50%), Gaps = 13/129 (10%) Query: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDS---ETAMFS 57 MGA+L +P K + G G L YG S+MQGWRV MEDAH + L S + F+ Sbjct: 1 MGAFLDKPKMEKHNAQGQGNG---LRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFA 57 Query: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYKEG-------KLQKALEDAFLAIDAKLTTEEV 110 VYDGH G +VA YC ++L D I + + +K ++ + FL ID + Sbjct: 58 VYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSE 117 Query: 111 IKELAQIAG 119 K A +G Sbjct: 118 KKHGADRSG 126 >gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens] Length = 455 Score = 130 bits (328), Expect = 2e-30 Identities = 81/218 (37%), Positives = 124/218 (56%), Gaps = 18/218 (8%) Query: 307 EEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDH 366 E +E M V M K+ SG+TAV LI + N GDSR ++ K + DH Sbjct: 180 EIDEHMRV--MSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDH 237 Query: 367 KPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKV 426 KP + +E RI+NAGG V M RVNG L +SRA+GD YK P EQ++S P++ Sbjct: 238 KPSNPLEKERIQNAGGSV-MIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHD 296 Query: 427 LTLT-DDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLA 485 + + +D +F+++ACDGIW+VM ++E+ DF++S++ D+ L + E++D CL Sbjct: 297 IERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDD------LEKVCNEVVDTCLY 350 Query: 486 PDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLE 523 + DNM+ I+ICF N ++ PE+ K++ E Sbjct: 351 KGSR------DNMSVILICFP--NAPKVSPEAVKKEAE 380 Score = 75.9 bits (185), Expect = 9e-14 Identities = 47/129 (36%), Positives = 65/129 (50%), Gaps = 13/129 (10%) Query: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDS---ETAMFS 57 MGA+L +P K + G G L YG S+MQGWRV MEDAH + L S + F+ Sbjct: 74 MGAFLDKPKMEKHNAQGQGNG---LRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFA 130 Query: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYKEG-------KLQKALEDAFLAIDAKLTTEEV 110 VYDGH G +VA YC ++L D I + + +K ++ + FL ID + Sbjct: 131 VYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSE 190 Query: 111 IKELAQIAG 119 K A +G Sbjct: 191 KKHGADRSG 199 >gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens] Length = 380 Score = 128 bits (321), Expect = 2e-29 Identities = 73/216 (33%), Positives = 123/216 (56%), Gaps = 25/216 (11%) Query: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM 386 SG+TAV +I K + N GDSR V+ G+ + DHKP + E RI+NAGG V + Sbjct: 130 SGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI 189 Query: 387 DGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNV 446 RVNG L +SRA+GD+ YK P EQ++S P++ + ++ EF+++ACDGIW+V Sbjct: 190 Q-RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDV 248 Query: 447 MSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK 506 MS++E+ ++++S++ D+ L ++ ++D CL + DNM+ +++CF Sbjct: 249 MSNEELCEYVKSRLEVSDD------LENVCNWVVDTCLHKGSR------DNMSIVLVCFS 296 Query: 507 PRNTAELQPESGKR----------KLEEVLSTEGAE 532 N ++ E+ K+ ++EE++ G E Sbjct: 297 --NAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEE 330 Score = 75.1 bits (183), Expect = 2e-13 Identities = 44/99 (44%), Positives = 57/99 (57%), Gaps = 7/99 (7%) Query: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNC---IPELDSETAMFS 57 MGA+L +P T K + G G L YG S+MQGWRV MEDAH IP + + F+ Sbjct: 1 MGAFLDKPKTEKHNAHGAGNG---LRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFA 57 Query: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYK-EGKLQKALE 95 VYDGH G VA YC+ +L + I + ++ GK ALE Sbjct: 58 VYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALE 96 >gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens] Length = 387 Score = 128 bits (321), Expect = 2e-29 Identities = 73/216 (33%), Positives = 123/216 (56%), Gaps = 25/216 (11%) Query: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM 386 SG+TAV +I K + N GDSR V+ G+ + DHKP + E RI+NAGG V + Sbjct: 130 SGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI 189 Query: 387 DGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNV 446 RVNG L +SRA+GD+ YK P EQ++S P++ + ++ EF+++ACDGIW+V Sbjct: 190 Q-RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDV 248 Query: 447 MSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK 506 MS++E+ ++++S++ D+ L ++ ++D CL + DNM+ +++CF Sbjct: 249 MSNEELCEYVKSRLEVSDD------LENVCNWVVDTCLHKGSR------DNMSIVLVCFS 296 Query: 507 PRNTAELQPESGKR----------KLEEVLSTEGAE 532 N ++ E+ K+ ++EE++ G E Sbjct: 297 --NAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEE 330 Score = 75.1 bits (183), Expect = 2e-13 Identities = 44/99 (44%), Positives = 57/99 (57%), Gaps = 7/99 (7%) Query: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNC---IPELDSETAMFS 57 MGA+L +P T K + G G L YG S+MQGWRV MEDAH IP + + F+ Sbjct: 1 MGAFLDKPKTEKHNAHGAGNG---LRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFA 57 Query: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYK-EGKLQKALE 95 VYDGH G VA YC+ +L + I + ++ GK ALE Sbjct: 58 VYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALE 96 >gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens] Length = 479 Score = 128 bits (321), Expect = 2e-29 Identities = 73/216 (33%), Positives = 123/216 (56%), Gaps = 25/216 (11%) Query: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM 386 SG+TAV +I K + N GDSR V+ G+ + DHKP + E RI+NAGG V + Sbjct: 130 SGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI 189 Query: 387 DGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNV 446 RVNG L +SRA+GD+ YK P EQ++S P++ + ++ EF+++ACDGIW+V Sbjct: 190 Q-RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDV 248 Query: 447 MSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK 506 MS++E+ ++++S++ D+ L ++ ++D CL + DNM+ +++CF Sbjct: 249 MSNEELCEYVKSRLEVSDD------LENVCNWVVDTCLHKGSR------DNMSIVLVCFS 296 Query: 507 PRNTAELQPESGKR----------KLEEVLSTEGAE 532 N ++ E+ K+ ++EE++ G E Sbjct: 297 --NAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEE 330 Score = 75.1 bits (183), Expect = 2e-13 Identities = 44/99 (44%), Positives = 57/99 (57%), Gaps = 7/99 (7%) Query: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNC---IPELDSETAMFS 57 MGA+L +P T K + G G L YG S+MQGWRV MEDAH IP + + F+ Sbjct: 1 MGAFLDKPKTEKHNAHGAGNG---LRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFA 57 Query: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYK-EGKLQKALE 95 VYDGH G VA YC+ +L + I + ++ GK ALE Sbjct: 58 VYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALE 96 >gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens] Length = 327 Score = 126 bits (317), Expect = 4e-29 Identities = 70/197 (35%), Positives = 116/197 (58%), Gaps = 15/197 (7%) Query: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM 386 SG+TAV +I K + N GDSR V+ G+ + DHKP + E RI+NAGG V + Sbjct: 130 SGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI 189 Query: 387 DGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNV 446 RVNG L +SRA+GD+ YK P EQ++S P++ + ++ EF+++ACDGIW+V Sbjct: 190 Q-RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDV 248 Query: 447 MSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK 506 MS++E+ ++++S++ D+ L ++ ++D CL + DNM+ +++CF Sbjct: 249 MSNEELCEYVKSRLEVSDD------LENVCNWVVDTCLHKGSR------DNMSIVLVCFS 296 Query: 507 PRNTAELQPESGKRKLE 523 N ++ E+ K+ E Sbjct: 297 --NAPKVSDEAVKKDSE 311 Score = 75.1 bits (183), Expect = 2e-13 Identities = 44/99 (44%), Positives = 57/99 (57%), Gaps = 7/99 (7%) Query: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNC---IPELDSETAMFS 57 MGA+L +P T K + G G L YG S+MQGWRV MEDAH IP + + F+ Sbjct: 1 MGAFLDKPKTEKHNAHGAGNG---LRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFA 57 Query: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYK-EGKLQKALE 95 VYDGH G VA YC+ +L + I + ++ GK ALE Sbjct: 58 VYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALE 96 >gi|122937199 protein phosphatase 1B-like [Homo sapiens] Length = 430 Score = 114 bits (284), Expect = 3e-25 Identities = 71/188 (37%), Positives = 102/188 (54%), Gaps = 17/188 (9%) Query: 328 GTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMD 387 G TAVV L+ + L +A+ GDSR V+S AG + DH+P E RI AGG + Sbjct: 162 GCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRR 221 Query: 388 GRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNVM 447 RV G L +SRA+GD YK PPE Q++SA P++ L + EFM++A DG+W+ + Sbjct: 222 -RVEGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAALARQAEDEFMLLASDGVWDTV 280 Query: 448 SSQEVVDFIQSKISQRDENGELRLLSSIV-EELLDQCLAPDTSGDGTGCDNMTCIIICF- 505 S + + S++ L L ++ +LLD CL + DNMTCI++CF Sbjct: 281 SGAALAGLVASRL-------RLGLAPELLCAQLLDTCLCKGS------LDNMTCILVCFP 327 Query: 506 -KPRNTAE 512 PR + E Sbjct: 328 GAPRPSEE 335 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 6/87 (6%) Query: 25 LPYGFSAMQGWRVSMEDAHNC---IPELDSETAMFSVYDGHGGEEVALYCAKYLPDIIKD 81 L +G SA QGWR MEDAH +P L A+F+V DGHGG A + A++LP + Sbjct: 65 LRFGASAAQGWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFGARHLPGHVLQ 124 Query: 82 QKAYKEGK---LQKALEDAFLAIDAKL 105 + + + +++AL AFL+ D +L Sbjct: 125 ELGPEPSEPEGVREALRRAFLSADERL 151 >gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens] Length = 360 Score = 100 bits (249), Expect = 3e-21 Identities = 66/196 (33%), Positives = 105/196 (53%), Gaps = 32/196 (16%) Query: 326 DSGTTAVVALIRGKQLIVANAGDSRCVVSEA-GKALDMSYDHKPEDEVELARIKNAGGKV 384 ++GTT ++AL+ K L VAN GDSR V+ + G A+ +S+DHKP E RIK AGG + Sbjct: 190 EAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFI 249 Query: 385 TMDG--RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDH---EFMVIA 439 + +G RV G L +SR++GD+ P + + +PD +LT D EFM++A Sbjct: 250 SFNGSWRVQGILAMSRSLGDY---------PLKNLNVVIPDPDILTFDLDKLQPEFMILA 300 Query: 440 CDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGC-DNM 498 DG+W+ S++E V FI+ ++ + + +L S GC DN+ Sbjct: 301 SDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYR----------------GCPDNI 344 Query: 499 TCIIICFKPRNTAELQ 514 T +++ F+ + E Q Sbjct: 345 TVMVVKFRNSSKTEEQ 360 Score = 46.2 bits (108), Expect = 8e-05 Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 9/84 (10%) Query: 31 AMQGWRVSMEDAHNCIPELDSET--AMFSVYDGHGGEEVALYCAKYLPDIIK----DQKA 84 ++QG R MED + +L ++T ++F ++DGHGGE A Y LP+ +K D + Sbjct: 97 SIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYEK 156 Query: 85 YKEGKL---QKALEDAFLAIDAKL 105 KE + Q LE L+ID ++ Sbjct: 157 DKENSVLSYQTILEQQILSIDREM 180 >gi|7661862 protein phosphatase 1F [Homo sapiens] Length = 454 Score = 91.7 bits (226), Expect = 2e-18 Identities = 60/152 (39%), Positives = 89/152 (58%), Gaps = 12/152 (7%) Query: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVT- 385 SGTT V ALI G L VA GDS+ ++ + G+ + + H+PE + E ARI+ GG V+ Sbjct: 253 SGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSH 312 Query: 386 MD-GRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIW 444 MD RVNG L +SRAIGD F K +S D LT +++++ACDG + Sbjct: 313 MDCWRVNGTLAVSRAIGDVFQK---------PYVSGEADAASRALTGSEDYLLLACDGFF 363 Query: 445 NVMSSQEVVDFIQSKISQRDENGELRLLSSIV 476 +V+ QEVV +QS ++++ +G LR+ +V Sbjct: 364 DVVPHQEVVGLVQSHLTRQQGSG-LRVAEELV 394 Score = 34.7 bits (78), Expect = 0.23 Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 8/53 (15%) Query: 31 AMQGWRVSMEDAHNCIPELDS--------ETAMFSVYDGHGGEEVALYCAKYL 75 A++ R MED H +P + A F+V+DGHGG + A Y A ++ Sbjct: 161 AIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV 213 >gi|30089948 protein phosphatase 1E [Homo sapiens] Length = 755 Score = 90.5 bits (223), Expect = 4e-18 Identities = 69/216 (31%), Positives = 108/216 (50%), Gaps = 27/216 (12%) Query: 328 GTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMD 387 GTT VV IRG L VA GDS+ ++ G+A+++ HKP+ E E RI+ GG V Sbjct: 329 GTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWF 388 Query: 388 G--RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWN 445 G RVNG L++SRAIGD +K I D L +++++ACDG ++ Sbjct: 389 GAWRVNGSLSVSRAIGDAEHK---------PYICGDADSASTVLDGTEDYLILACDGFYD 439 Query: 446 VMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICF 505 ++ E V + + ++ NG+ SS+V L ++ D DN+T I++ Sbjct: 440 TVNPDEAVKVVSDHL--KENNGD----SSMVAHKL-----VASARDAGSSDNITVIVVFL 488 Query: 506 KPRNTA-ELQPESGKRKLEEVLSTEGAEENGNSDKK 540 + N A + ES + S +G +E+G DK+ Sbjct: 489 RDMNKAVNVSEESDWTE----NSFQGGQEDGGDDKE 520 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%) Query: 21 PRLPLPYGFSAMQGWRVSMEDAHNCIPELD--------SETAMFSVYDGHGGEEVALYCA 72 P+L A++ R MED H CIP+ + E A F+V+DGHGG + A+Y + Sbjct: 226 PQLYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYAS 285 Query: 73 KYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKEL 114 +L + Q+ + + AL AF D + + + L Sbjct: 286 IHLHVNLVRQEMFPHDPAE-ALCRAFRVTDERFVQKAARESL 326 Score = 33.9 bits (76), Expect = 0.39 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 16/108 (14%) Query: 206 PTAKAYTGFSS---NSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSED 262 P K Y F RG G EP P E P S + P + E Sbjct: 6 PEEKTYRRFLELFLGEFRGPCGGGEPEPE-PEPEPEPEPESEPEPEPELV--------EA 56 Query: 263 ESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEE 310 E+ EA EE E + ++EE + E+D + EEA + EEEEE Sbjct: 57 EAAEASVEEPGEEAATVA----ATEEGDQEQDPEPEEEAAVEGEEEEE 100 Score = 32.7 bits (73), Expect = 0.88 Identities = 28/77 (36%), Positives = 33/77 (42%), Gaps = 5/77 (6%) Query: 258 EDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDED--DTEEA-EEDDEEEEEEMMV 314 E + E E E E E E E +S E EE TEE +E D E EEE V Sbjct: 34 EPEPEPEPEPESEPEPEPELVEAEAAEASVEEPGEEAATVAATEEGDQEQDPEPEEEAAV 93 Query: 315 PGMEGKEEPGSDSGTTA 331 G E EE G+ + A Sbjct: 94 EGEE--EEEGAATAAAA 108 >gi|13540531 integrin-linked kinase-associated protein phosphatase 2C [Homo sapiens] Length = 392 Score = 89.0 bits (219), Expect = 1e-17 Identities = 55/144 (38%), Positives = 81/144 (56%), Gaps = 15/144 (10%) Query: 321 EEPGSDSGTTAVVALIRGKQLIVANAGDSRCVV------SEAGKALDMSYDHKPEDEVEL 374 ++P G+TA L L +AN GDSR ++ S+ AL +S +H P E Sbjct: 209 QKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEER 268 Query: 375 ARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHE 434 RI+ AGG V DGRV G L +SR+IGD YKR ++++PDI+ LT + Sbjct: 269 MRIQKAGGNVR-DGRVLGVLEVSRSIGDGQYKRCG--------VTSVPDIRRCQLTPNDR 319 Query: 435 FMVIACDGIWNVMSSQEVVDFIQS 458 F+++ACDG++ V + +E V+FI S Sbjct: 320 FILLACDGLFKVFTPEEAVNFILS 343 Score = 32.3 bits (72), Expect = 1.1 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 20/96 (20%) Query: 33 QGWRVSMEDAHNCIPELDSE----------TAMFSVYDGHGGEEVALYCAKYLPDII--- 79 +G R M+DAH + ++ E + F+V+DGHGG + + A+ L + Sbjct: 115 KGEREEMQDAHVILNDITEECRPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRK 174 Query: 80 --KDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKE 113 K E +++ L D F K T EE +K+ Sbjct: 175 FPKGDVISVEKTVKRCLLDTF-----KHTDEEFLKQ 205 >gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo sapiens] Length = 372 Score = 83.6 bits (205), Expect = 4e-16 Identities = 54/136 (39%), Positives = 79/136 (58%), Gaps = 14/136 (10%) Query: 327 SGTTAVVALIR-GKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVT 385 SGTTA VAL+R G +L+VA+ GDSR ++ GK + ++ DH PE + E RIK GG V Sbjct: 186 SGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVA 245 Query: 386 MDG----RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTD-DHEFMVIAC 440 + VNG L ++R+IGD L + + A P+ K + L D F+V+ Sbjct: 246 WNSLGQPHVNGRLAMTRSIGD--------LDLKTSGVIAEPETKRIKLHHADDSFLVLTT 297 Query: 441 DGIWNVMSSQEVVDFI 456 DGI +++SQE+ DF+ Sbjct: 298 DGINFMVNSQEICDFV 313 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/87 (35%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Query: 17 GVGAPRLPLP-YGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYDGHGGEEVALYCAKYL 75 G P++ L G ++ G R ED + +L E F+VYDGHGG A +C ++ Sbjct: 84 GKPIPKISLENVGCASQIGKRKENEDRFD-FAQLTDEVLYFAVYDGHGGPAAADFCHTHM 142 Query: 76 PDIIKDQKAYKEGKLQKALEDAFLAID 102 I D KE L+ L AFL ID Sbjct: 143 EKCIMDLLP-KEKNLETLLTLAFLEID 168 >gi|4505997 protein phosphatase 1D [Homo sapiens] Length = 605 Score = 69.7 bits (169), Expect = 6e-12 Identities = 60/215 (27%), Positives = 99/215 (46%), Gaps = 38/215 (17%) Query: 325 SDSGTTAVVALIRGKQLIVANAGDSRCVVS-------EAGKALDMSYDHKPEDEVELARI 377 S SGTTA V +IRG ++ VA+ GDS V+ + +A++++ DHKPE E RI Sbjct: 169 STSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERI 228 Query: 378 KNAGGKVTMDGRVNGG------------------------LNLSRAIGDHFYKRNKNLPP 413 + GG V VN L ++RA+GD + + + Sbjct: 229 EGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLW---SYDFFS 285 Query: 414 EEQMISALPDIKVLTLTDD-HEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLL 472 E ++S PD V TL H+++++ DG+WN++ Q+ + Q + ++ GE Sbjct: 286 GEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHG-- 343 Query: 473 SSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKP 507 S + L+++ L DN + I+IC P Sbjct: 344 QSCAKMLVNRALG-RWRQRMLRADNTSAIVICISP 377 Score = 39.7 bits (91), Expect = 0.007 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 15/91 (16%) Query: 25 LPYGFSAMQGWRVSMEDAHNCIPELD------------SETAMFSVYDGHGGEEVALYCA 72 LP G + +G V+ +A + +P+ S A F+V DGHGG E A + Sbjct: 58 LPGGEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAR 117 Query: 73 KYLPDIIKDQKAY---KEGKLQKALEDAFLA 100 ++L IK QK + + K+ A+ FLA Sbjct: 118 EHLWGFIKKQKGFTSSEPAKVCAAIRKGFLA 148 >gi|4503257 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 65.9 bits (159), Expect = 9e-11 Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 16/130 (12%) Query: 213 GFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEE 272 G SS+S EA G P+G A C SAS +++DE DE +EEE Sbjct: 400 GTSSHSADTPEASLDSGEG-PSGMASQGCPSASRA-----------ETDDEDDEESDEEE 447 Query: 273 DSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDE-EEEEEMMVPGMEGKEEPGSDSGTTA 331 + EE EEE+ SEE EED + +E +EDDE E+EEE G +G + P S + Sbjct: 448 EEEEEEEEEEATDSEE---EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504 Query: 332 VVALIRGKQL 341 L GKQ+ Sbjct: 505 EKNLEPGKQI 514 Score = 35.4 bits (80), Expect = 0.14 Identities = 19/81 (23%), Positives = 39/81 (48%) Query: 242 SSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEA 301 S ++ R A+ + ++ EA + + + S+ AE ++++D+ + Sbjct: 386 SEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDE 445 Query: 302 EEDDEEEEEEMMVPGMEGKEE 322 EE++EEEEEE E +E+ Sbjct: 446 EEEEEEEEEEEEATDSEEEED 466 Score = 30.4 bits (67), Expect = 4.3 Identities = 46/244 (18%), Positives = 88/244 (36%), Gaps = 7/244 (2%) Query: 89 KLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLHEE 148 +LQ +DAF + +L + + T+D A D V Sbjct: 308 QLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSL 367 Query: 149 ATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTA 208 A ++E++++Y K S+ G QG + + D+ + GP+ Sbjct: 368 AMSRLDEVISKYAMLQDK----SEEGERKKRRARLQGTSSHSA--DTPEASLDSGEGPSG 421 Query: 209 KAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAE 268 A G S S T+ E E + + ++ +++ +E + Sbjct: 422 MASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 481 Query: 269 EEEEDSEECSEEEDGYSSEEAENEED-EDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDS 327 EEEE + ++ SS + NE++ E + + E++ + +V EEP + S Sbjct: 482 EEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPS 541 Query: 328 GTTA 331 A Sbjct: 542 SIDA 545 >gi|215422388 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 65.9 bits (159), Expect = 9e-11 Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 16/130 (12%) Query: 213 GFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEE 272 G SS+S EA G P+G A C SAS +++DE DE +EEE Sbjct: 400 GTSSHSADTPEASLDSGEG-PSGMASQGCPSASRA-----------ETDDEDDEESDEEE 447 Query: 273 DSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDE-EEEEEMMVPGMEGKEEPGSDSGTTA 331 + EE EEE+ SEE EED + +E +EDDE E+EEE G +G + P S + Sbjct: 448 EEEEEEEEEEATDSEE---EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504 Query: 332 VVALIRGKQL 341 L GKQ+ Sbjct: 505 EKNLEPGKQI 514 Score = 35.4 bits (80), Expect = 0.14 Identities = 19/81 (23%), Positives = 39/81 (48%) Query: 242 SSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEA 301 S ++ R A+ + ++ EA + + + S+ AE ++++D+ + Sbjct: 386 SEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDE 445 Query: 302 EEDDEEEEEEMMVPGMEGKEE 322 EE++EEEEEE E +E+ Sbjct: 446 EEEEEEEEEEEEATDSEEEED 466 Score = 30.4 bits (67), Expect = 4.3 Identities = 46/244 (18%), Positives = 88/244 (36%), Gaps = 7/244 (2%) Query: 89 KLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLHEE 148 +LQ +DAF + +L + + T+D A D V Sbjct: 308 QLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSL 367 Query: 149 ATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTA 208 A ++E++++Y K S+ G QG + + D+ + GP+ Sbjct: 368 AMSRLDEVISKYAMLQDK----SEEGERKKRRARLQGTSSHSA--DTPEASLDSGEGPSG 421 Query: 209 KAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAE 268 A G S S T+ E E + + ++ +++ +E + Sbjct: 422 MASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 481 Query: 269 EEEEDSEECSEEEDGYSSEEAENEED-EDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDS 327 EEEE + ++ SS + NE++ E + + E++ + +V EEP + S Sbjct: 482 EEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPS 541 Query: 328 GTTA 331 A Sbjct: 542 SIDA 545 >gi|215422366 death-domain associated protein isoform b [Homo sapiens] Length = 752 Score = 65.9 bits (159), Expect = 9e-11 Identities = 49/130 (37%), Positives = 65/130 (50%), Gaps = 16/130 (12%) Query: 213 GFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEE 272 G SS+S EA G P+G A C SAS +++DE DE +EEE Sbjct: 412 GTSSHSADTPEASLDSGEG-PSGMASQGCPSASRA-----------ETDDEDDEESDEEE 459 Query: 273 DSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDE-EEEEEMMVPGMEGKEEPGSDSGTTA 331 + EE EEE+ SEE EED + +E +EDDE E+EEE G +G + P S + Sbjct: 460 EEEEEEEEEEATDSEE---EEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 516 Query: 332 VVALIRGKQL 341 L GKQ+ Sbjct: 517 EKNLEPGKQI 526 Score = 35.4 bits (80), Expect = 0.14 Identities = 19/81 (23%), Positives = 39/81 (48%) Query: 242 SSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEA 301 S ++ R A+ + ++ EA + + + S+ AE ++++D+ + Sbjct: 398 SEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDE 457 Query: 302 EEDDEEEEEEMMVPGMEGKEE 322 EE++EEEEEE E +E+ Sbjct: 458 EEEEEEEEEEEEATDSEEEED 478 Score = 30.4 bits (67), Expect = 4.3 Identities = 46/244 (18%), Positives = 88/244 (36%), Gaps = 7/244 (2%) Query: 89 KLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLHEE 148 +LQ +DAF + +L + + T+D A D V Sbjct: 320 QLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSL 379 Query: 149 ATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTA 208 A ++E++++Y K S+ G QG + + D+ + GP+ Sbjct: 380 AMSRLDEVISKYAMLQDK----SEEGERKKRRARLQGTSSHSA--DTPEASLDSGEGPSG 433 Query: 209 KAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAE 268 A G S S T+ E E + + ++ +++ +E + Sbjct: 434 MASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEED 493 Query: 269 EEEEDSEECSEEEDGYSSEEAENEED-EDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDS 327 EEEE + ++ SS + NE++ E + + E++ + +V EEP + S Sbjct: 494 EEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPS 553 Query: 328 GTTA 331 A Sbjct: 554 SIDA 557 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 64.7 bits (156), Expect = 2e-10 Identities = 62/219 (28%), Positives = 83/219 (37%), Gaps = 22/219 (10%) Query: 119 GRPTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTG 178 G E E+E E+ E + + E E EE G+ +G + G G G Sbjct: 862 GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKG 921 Query: 179 EEPGSQGLN------GEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGI 232 EE G +G GE ED E +E + G E G G+ GE Sbjct: 922 EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEG-- 979 Query: 233 PTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENE 292 GE ++ E E+ +E E EEE E EEE+G E E E Sbjct: 980 -EGEEEEGEGEGEEE----------EGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGE 1028 Query: 293 EDEDDTEEAEEDDEEEEEEMMVPGME---GKEEPGSDSG 328 E E + EE E ++E EE E G E +EE + G Sbjct: 1029 EGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEG 1067 Score = 63.9 bits (154), Expect = 4e-10 Identities = 63/229 (27%), Positives = 91/229 (39%), Gaps = 18/229 (7%) Query: 113 ELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSK 172 E+ + G E+E+E E +E + + EE EE EE G+ +G + Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE----EGEE-GEGEEEGE 872 Query: 173 SGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGI 232 G G GEE +G E G + E E + +G E G+ GE G Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGE-GE 931 Query: 233 PTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENE 292 E G + + E+E E E EEE+ E EEE EE E E Sbjct: 932 GEEEEGEGEGEDGEG-----------EGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGE 980 Query: 293 EDEDDTE-EAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQ 340 +E++ E E EE++ EEE E G E E G + V + G++ Sbjct: 981 GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029 Score = 59.3 bits (142), Expect = 9e-09 Identities = 67/245 (27%), Positives = 97/245 (39%), Gaps = 34/245 (13%) Query: 87 EGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLH 146 EG+ + A ++ + D + E+ KE Q G E E E+ +E+ + EE Sbjct: 691 EGEKELAEKEEWKKRDGE---EQEQKEREQ--GHQKERNQEMEEGGEEEHGEGEE----- 740 Query: 147 EEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGP 206 EE EE + G+ +G G EE G + AG E+ E Q G Sbjct: 741 EEGDREEEE--EKEGEGKEEGEGEEVEGEREKEE-GERKKEERAGKEEKGEEEGDQGEGE 797 Query: 207 TAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDE 266 + E E G+V + G+ + + E+ E E +E Sbjct: 798 EEET----EGRGEEKEEGGEVEGGEVEEGKG--------------EREEEEEEGEGEEEE 839 Query: 267 AEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEE---EEMMVPGMEGKEEP 323 E EEE+ E EE +G EE E E E++ EE E + EEEE E EG+EE Sbjct: 840 GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEE 899 Query: 324 GSDSG 328 G G Sbjct: 900 GEGEG 904 Score = 52.4 bits (124), Expect = 1e-06 Identities = 61/207 (29%), Positives = 74/207 (35%), Gaps = 32/207 (15%) Query: 123 EDEDEKEKVADEDDVDNE-EAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEP 181 E+E+EKE E+ E E EE EE R G+ KG G G EE Sbjct: 746 EEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE---RAGKE-EKGEEEGDQGEGEEEET 801 Query: 182 GSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSC 241 +G E G E E G + E G + GE GE Sbjct: 802 EGRGEEKEEGGE--------VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE 853 Query: 242 SSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEA 301 + E E E EEE E+ E EEE+G E E E E + EE Sbjct: 854 GEGKG------------EEEGEEGEGEEEGEEGEGEGEEEEG-EGEGEEEGEGEGEEEEG 900 Query: 302 EEDDEEEEEEMMVPGMEGKEEPGSDSG 328 E + EEE E EG+EE G G Sbjct: 901 EGEGEEEGEG------EGEEEEGEGKG 921 Score = 52.0 bits (123), Expect = 1e-06 Identities = 52/193 (26%), Positives = 73/193 (37%), Gaps = 39/193 (20%) Query: 119 GRPTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTG 178 G E+E E E E + + EE EE EE G+ +G + G G G Sbjct: 930 GEGEEEEGEGEGEDGEGEGEEEEGEWEGEE-----EE---GEGEGEEEGEGEGEEGEGEG 981 Query: 179 EEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAG 238 EE GE E+ E +E G + G E G G+V GE G Sbjct: 982 EEE-----EGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEV------EGEEG 1030 Query: 239 PSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDT 298 + E E +E EEE E+ E+ E E+ + E E EE+ Sbjct: 1031 --------------------EGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQ 1070 Query: 299 EEAEEDDEEEEEE 311 E EE++E ++ E Sbjct: 1071 ETGEEENERQDGE 1083 Score = 49.3 bits (116), Expect = 9e-06 Identities = 67/272 (24%), Positives = 105/272 (38%), Gaps = 20/272 (7%) Query: 77 DIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIK-ELAQIAGRPTEDEDEKEKVADED 135 D ++ KEGK K + + TT E E +I ED K +E Sbjct: 545 DEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQ 604 Query: 136 DVD-NEEAALLH---EEATMTIEELLT---RYGQNCHKGPPHSKSGG-GTGEEPGSQGLN 187 +V+ NEE +H +E T + + LT + K ++ G G G+ +G + Sbjct: 605 EVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSS 664 Query: 188 GEAGPEDSTRETPSQENG--PTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSAS 245 G +D RE ++ G + G +E+ + GE + Sbjct: 665 GAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERN 724 Query: 246 DKLPRVAKSKFFEDSEDESDEAEEEEEDSE-----ECSEEEDGYSSEEAENEEDE----D 296 ++ + + E E+E D EEEE++ E E E E EE E +++E + Sbjct: 725 QEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKE 784 Query: 297 DTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSG 328 + E E D E EEE E KEE G G Sbjct: 785 EKGEEEGDQGEGEEEETEGRGEEKEEGGEVEG 816 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 64.3 bits (155), Expect = 3e-10 Identities = 35/80 (43%), Positives = 48/80 (60%), Gaps = 3/80 (3%) Query: 252 AKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEE 311 +K K E+E +E EEEEE+ EE EEE+ EE E EE+E++ EE EE++EEEEEE Sbjct: 249 SKQKGILSHEEEDEEEEEEEEEEEEDEEEEE---EEEEEEEEEEEEEEEEEEEEEEEEEE 305 Query: 312 MMVPGMEGKEEPGSDSGTTA 331 P + +E+ S A Sbjct: 306 EAAPDVIFQEDTSHTSAQKA 325 Score = 58.2 bits (139), Expect = 2e-08 Identities = 29/68 (42%), Positives = 40/68 (58%) Query: 244 ASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEE 303 + D P+ + E+S + EEED EE EEE+ EE E EE+E++ EE EE Sbjct: 232 SQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291 Query: 304 DDEEEEEE 311 ++EEEEEE Sbjct: 292 EEEEEEEE 299 Score = 55.1 bits (131), Expect = 2e-07 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 5/81 (6%) Query: 258 EDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEED-----DEEEEEEM 312 E+ E+E +E +EEEE+ EE EEE+ EE E EE+E++ EEA D D Sbjct: 264 EEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQ 323 Query: 313 MVPGMEGKEEPGSDSGTTAVV 333 P + G E P + +V Sbjct: 324 KAPELRGPESPSPKPEYSVIV 344 Score = 42.7 bits (99), Expect = 8e-04 Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 11/76 (14%) Query: 258 EDSEDESDEAEEEEED----------SEECSEEEDGYSSEEAENEEDEDDTEEAE-EDDE 306 ED+E+ + E +D SEE S+++ S EE + EE+E++ EE E E++E Sbjct: 219 EDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEE 278 Query: 307 EEEEEMMVPGMEGKEE 322 EEEEE E +EE Sbjct: 279 EEEEEEEEEEEEEEEE 294 Score = 36.6 bits (83), Expect = 0.061 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 3/101 (2%) Query: 223 EAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEE-CSEEE 281 + GQ +PG G +A + F ED + E E S++ C + Sbjct: 183 DLGQAAKPG--PGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL 240 Query: 282 DGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEE 322 + +SEE+ ++ EE +E++EEEEEE E +EE Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEE 281 Score = 34.3 bits (77), Expect = 0.30 Identities = 29/110 (26%), Positives = 39/110 (35%), Gaps = 48/110 (43%) Query: 258 EDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEE------------------------ 293 E+ EDE +E EEEEE+ EE EEE+ EE E EE Sbjct: 270 EEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELR 329 Query: 294 ---------------------DEDDTEEAEED---DEEEEEEMMVPGMEG 319 D+D+ + + DE E ++MM G G Sbjct: 330 GPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLG 379 Score = 30.8 bits (68), Expect = 3.3 Identities = 18/73 (24%), Positives = 37/73 (50%) Query: 71 CAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEK 130 C + L D ++ + ++G L ED + + E+ +E + E+E+E+E+ Sbjct: 236 CPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEE 295 Query: 131 VADEDDVDNEEAA 143 +E++ + EEAA Sbjct: 296 EEEEEEEEEEEAA 308 Score = 29.3 bits (64), Expect = 9.7 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%) Query: 193 EDSTRETPSQENGPTAKAYTGFSS-NSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRV 251 E+ T + ++ A+ SS +S G ++ + T + PS S S + + Sbjct: 665 ENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSST--SAPSSSMTSPQSSQA 722 Query: 252 AKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEE 309 ++ ++ D + + EE+ EE ++S EA DD E +EE+ EE + Sbjct: 723 SRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEA------DDQEVSEENFEERK 774 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/95 (38%), Positives = 56/95 (58%), Gaps = 2/95 (2%) Query: 238 GPSCSSASDKLPRVAKSKFFEDSEDESDEAE-EEEEDSEECSEEEDGYSSEEAENEEDED 296 GP+ S+ L ++S+ +D EDE DE E EEEED E EDG S E+ +E++ + Sbjct: 624 GPNPKSSRTTLQSKSESEE-DDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 682 Query: 297 DTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTA 331 D +E EEDDE+E+++ E E GS S +++ Sbjct: 683 DGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS 717 Score = 35.0 bits (79), Expect = 0.18 Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 13/90 (14%) Query: 217 NSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSED--ESDEAEEEEEDS 274 + E E + E G + + G S S+S+ ++SED E++E +E+E+D Sbjct: 649 DDEDEDEEEEDDENGDSSEDGGDSSESSSE-----------DESEDGDENEEDDEDEDDD 697 Query: 275 EECSEEEDGYSSEEAENEEDEDDTEEAEED 304 E+ E+ED S + + D+ +++ + Sbjct: 698 EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727 Score = 33.9 bits (76), Expect = 0.39 Identities = 20/80 (25%), Positives = 33/80 (41%), Gaps = 1/80 (1%) Query: 250 RVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEE-E 308 R A ++ + + S + + S E+ E +ED++D +E EEDDE + Sbjct: 605 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD 664 Query: 309 EEEMMVPGMEGKEEPGSDSG 328 E E E S+ G Sbjct: 665 SSEDGGDSSESSSEDESEDG 684 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/95 (38%), Positives = 56/95 (58%), Gaps = 2/95 (2%) Query: 238 GPSCSSASDKLPRVAKSKFFEDSEDESDEAE-EEEEDSEECSEEEDGYSSEEAENEEDED 296 GP+ S+ L ++S+ +D EDE DE E EEEED E EDG S E+ +E++ + Sbjct: 624 GPNPKSSRTTLQSKSESEE-DDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 682 Query: 297 DTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTA 331 D +E EEDDE+E+++ E E GS S +++ Sbjct: 683 DGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS 717 Score = 35.0 bits (79), Expect = 0.18 Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 13/90 (14%) Query: 217 NSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSED--ESDEAEEEEEDS 274 + E E + E G + + G S S+S+ ++SED E++E +E+E+D Sbjct: 649 DDEDEDEEEEDDENGDSSEDGGDSSESSSE-----------DESEDGDENEEDDEDEDDD 697 Query: 275 EECSEEEDGYSSEEAENEEDEDDTEEAEED 304 E+ E+ED S + + D+ +++ + Sbjct: 698 EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727 Score = 33.9 bits (76), Expect = 0.39 Identities = 20/80 (25%), Positives = 33/80 (41%), Gaps = 1/80 (1%) Query: 250 RVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEE-E 308 R A ++ + + S + + S E+ E +ED++D +E EEDDE + Sbjct: 605 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD 664 Query: 309 EEEMMVPGMEGKEEPGSDSG 328 E E E S+ G Sbjct: 665 SSEDGGDSSESSSEDESEDG 684 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/95 (38%), Positives = 56/95 (58%), Gaps = 2/95 (2%) Query: 238 GPSCSSASDKLPRVAKSKFFEDSEDESDEAE-EEEEDSEECSEEEDGYSSEEAENEEDED 296 GP+ S+ L ++S+ +D EDE DE E EEEED E EDG S E+ +E++ + Sbjct: 661 GPNPKSSRTTLQSKSESEE-DDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 719 Query: 297 DTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTA 331 D +E EEDDE+E+++ E E GS S +++ Sbjct: 720 DGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS 754 Score = 35.0 bits (79), Expect = 0.18 Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 13/90 (14%) Query: 217 NSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSED--ESDEAEEEEEDS 274 + E E + E G + + G S S+S+ ++SED E++E +E+E+D Sbjct: 686 DDEDEDEEEEDDENGDSSEDGGDSSESSSE-----------DESEDGDENEEDDEDEDDD 734 Query: 275 EECSEEEDGYSSEEAENEEDEDDTEEAEED 304 E+ E+ED S + + D+ +++ + Sbjct: 735 EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764 Score = 33.9 bits (76), Expect = 0.39 Identities = 20/80 (25%), Positives = 33/80 (41%), Gaps = 1/80 (1%) Query: 250 RVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEE-E 308 R A ++ + + S + + S E+ E +ED++D +E EEDDE + Sbjct: 642 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD 701 Query: 309 EEEMMVPGMEGKEEPGSDSG 328 E E E S+ G Sbjct: 702 SSEDGGDSSESSSEDESEDG 721 >gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo sapiens] Length = 529 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 33/171 (19%) Query: 327 SGTTAVVALIRGKQLIVANAGDSRCVV-----SEAGKALDMSYDHKPEDEVELARIKNAG 381 SG TA +A + G L VANAGD R ++ + L ++ DH ++ EL+R+K Sbjct: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREH 324 Query: 382 GK-----VTMDGRVNGGLNLSRAIGDHFYKRNKNL--------------------PPE-- 414 + + M+ R+ G L RA GD K +K L PP Sbjct: 325 PESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYY 384 Query: 415 -EQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRD 464 ++A P++ L +F+V+A DG+W+++S+++VV + +++ D Sbjct: 385 TPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEAD 435 >gi|38788260 bromodomain PHD finger transcription factor isoform 2 [Homo sapiens] Length = 2903 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/148 (31%), Positives = 64/148 (43%), Gaps = 11/148 (7%) Query: 165 HKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEA 224 H+G + E L+ G S R+ P P + + G RG Sbjct: 43 HRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPG------RGGRG 96 Query: 225 GQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGY 284 G G TG G A R A +K D + ES+E EEEE+ E EEEDG Sbjct: 97 GGGGR----TGGGGGGGHLARTTAARRAVNKVVYD-DHESEEEEEEEDMVSEEEEEEDGD 151 Query: 285 SSEEAENEEDEDDTEEAEEDDEEEEEEM 312 + E ++E+DE+D E ++DD + EEM Sbjct: 152 AEETQDSEDDEEDEMEEDDDDSDYPEEM 179 Score = 33.5 bits (75), Expect = 0.51 Identities = 15/52 (28%), Positives = 30/52 (57%) Query: 258 EDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEE 309 E++E + +E E + +D+E+ EE + S E+ +++ DD E + +E E Sbjct: 574 EETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTE 625 Score = 32.7 bits (73), Expect = 0.88 Identities = 18/45 (40%), Positives = 22/45 (48%) Query: 282 DGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSD 326 D + SEE E EED EE EED + EE + E + E D Sbjct: 127 DDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDD 171 Score = 31.2 bits (69), Expect = 2.5 Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 3/59 (5%) Query: 265 DEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEP 323 D + EE ++ +E E+ E EE ED + E + DD+ +++ P EEP Sbjct: 568 DNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDDD---PEQGKSEEP 623 >gi|38788274 bromodomain PHD finger transcription factor isoform 1 [Homo sapiens] Length = 2920 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/148 (31%), Positives = 64/148 (43%), Gaps = 11/148 (7%) Query: 165 HKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEA 224 H+G + E L+ G S R+ P P + + G RG Sbjct: 43 HRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPG------RGGRG 96 Query: 225 GQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGY 284 G G TG G A R A +K D + ES+E EEEE+ E EEEDG Sbjct: 97 GGGGR----TGGGGGGGHLARTTAARRAVNKVVYD-DHESEEEEEEEDMVSEEEEEEDGD 151 Query: 285 SSEEAENEEDEDDTEEAEEDDEEEEEEM 312 + E ++E+DE+D E ++DD + EEM Sbjct: 152 AEETQDSEDDEEDEMEEDDDDSDYPEEM 179 Score = 37.7 bits (86), Expect = 0.027 Identities = 34/154 (22%), Positives = 74/154 (48%), Gaps = 22/154 (14%) Query: 258 EDSEDESDEAEEEEEDSEECSEE-EDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPG 316 E++E + +E E + +D+E+ EE ED ++++++ +DD E+ + + + + E Sbjct: 574 EETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEVGDFKSEK--SN 631 Query: 317 MEGKEEPGSD---SGTTAVVALIRG---------KQLIVANAGDSRCVVSEAGKALDMSY 364 E E PG+ SG+T ++ +R Q + A A ++ + E + L ++ Sbjct: 632 GELSESPGAGKGASGSTRIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVLVVN- 690 Query: 365 DHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSR 398 + E++R+ + +V M G +N L + Sbjct: 691 -----SQGEISRL-STKKEVIMKGNINNYFKLGQ 718 Score = 32.7 bits (73), Expect = 0.88 Identities = 18/45 (40%), Positives = 22/45 (48%) Query: 282 DGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSD 326 D + SEE E EED EE EED + EE + E + E D Sbjct: 127 DDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDD 171 Score = 30.8 bits (68), Expect = 3.3 Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 4/60 (6%) Query: 265 DEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPG 324 D + EE ++ +E E+ E EE ED + E + DD+ +++ +GK E G Sbjct: 568 DNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDDD----PEQGKSEVG 623 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 61.6 bits (148), Expect = 2e-09 Identities = 56/188 (29%), Positives = 80/188 (42%), Gaps = 32/188 (17%) Query: 175 GGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPT 234 G E PG Q EA +ST E P +E + T S E E GE T Sbjct: 735 GDQKENPGGQEDVAEA---ESTGEMPGEEGETAGEGETEEKSGGETQPE----GEGETET 787 Query: 235 GEAGPSCSSASDKLPRVAKSKFFEDSEDESD--------EAEEEEEDSEECSEE------ 280 G C ++ A+ K + EDE + + E E +S+E S E Sbjct: 788 QGKGEECEDENE-----AEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAK 842 Query: 281 ------EDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVA 334 EDG S+ ++EE+E++ EE EE++EEEE+E E +EE G++ + Sbjct: 843 NDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWP 902 Query: 335 LIRGKQLI 342 R KQ I Sbjct: 903 ETRQKQAI 910 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 61.6 bits (148), Expect = 2e-09 Identities = 68/276 (24%), Positives = 107/276 (38%), Gaps = 77/276 (27%) Query: 123 EDEDEKEKVADEDDVDNEEAA-------LLHEEATMTIEELLTRYGQNCHKGPPHSKSGG 175 E+ED++E + E+ + +A LL E + +EELL +GP Sbjct: 295 EEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLLEGP------S 348 Query: 176 GTGEEPGSQGLNGEAGPEDSTRETPSQ--ENGPTAKAYT--------------GFSSNSE 219 + P S + GPE+ E P Q E P A T F++N E Sbjct: 349 SPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEE 408 Query: 220 RG-----------------------TEAGQVGEPGIP------TGEAGPSCSSASD---- 246 +E + GE + G P S+ D Sbjct: 409 EAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYAPGSGSSEDEDED 468 Query: 247 -----------KLPRVAKSKFFEDSEDESDEAEEEEEDSE-ECSEEED---GYSSEEAEN 291 + P A+ EDS +SD E+ ED E E SEEE+ +SEE+E+ Sbjct: 469 EVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESES 528 Query: 292 EEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDS 327 EE ED +++ D+EEE+++ V + ++E S++ Sbjct: 529 EESEDAQSQSQADEEEEDDDFGVEYLLARDEEQSEA 564 Score = 33.1 bits (74), Expect = 0.67 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 5/86 (5%) Query: 240 SCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTE 299 S S+AS P ++ +D + + E+EEED EE E E+ +AE + E + Sbjct: 268 SSSAASSPPPPASR---LDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELL 324 Query: 300 EAEEDDEEEEEEMMVPG--MEGKEEP 323 E + EE +P +EG P Sbjct: 325 RREGELPLEELLRSLPPQLLEGPSSP 350 Score = 31.6 bits (70), Expect = 2.0 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 3/57 (5%) Query: 87 EGKLQKALEDAFLAIDAKLTTEEVIKELAQI---AGRPTEDEDEKEKVADEDDVDNE 140 EG++ A+E + LA + +L+ EE++++ A +EDEDE E A+ D + E Sbjct: 424 EGEVDHAMELSELAREGELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPE 480 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 60.5 bits (145), Expect = 4e-09 Identities = 65/275 (23%), Positives = 117/275 (42%), Gaps = 36/275 (13%) Query: 123 EDEDEKEKVADEDDVDNEEAALLHEE----ATMTIEELLTRYGQNCHKGPPHSKSGGGTG 178 + EDE+ +EDD EE + ++ A + ++++ + P K+ G Sbjct: 27 DSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPG 86 Query: 179 EEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQ--VGEPGIPTGE 236 ++ + TP+++ AKA T + ++G G+ V PG G Sbjct: 87 KKAAA---------------TPAKKTVTPAKAVT---TPGKKGATPGKALVATPG-KKGA 127 Query: 237 AGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEE---DGYSSEEAENEE 293 A P+ + + K + S ED + E DE ++E+ED +E E ++ A +E Sbjct: 128 AIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDE 187 Query: 294 DEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLI-----VANAGD 348 D++D E+ E+DD++EE++ ME G + A V ++ K + + D Sbjct: 188 DDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKA---AKVVPVKAKNVAEDEDEEEDDED 244 Query: 349 SRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGK 383 E + D D + E+E E +K A GK Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGK 279 Score = 52.8 bits (125), Expect = 8e-07 Identities = 41/175 (23%), Positives = 68/175 (38%), Gaps = 40/175 (22%) Query: 172 KSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPG 231 K G + G N + D + S+E+ + + + ++ Sbjct: 124 KKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDE---------EDDEDEDEDEDEIEPAA 174 Query: 232 IPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEE--------------------- 270 + A P+ D+ + +D +DE D++EEE Sbjct: 175 MKAAAAAPASEDEDDEDDEDDE----DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAK 230 Query: 271 ----EEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKE 321 +ED EE E+ED E+ E+++DEDD EE EE++EE +E PG KE Sbjct: 231 NVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE--APGKRKKE 283 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/79 (30%), Positives = 42/79 (53%) Query: 253 KSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEM 312 K+K + EDE ++ E+E++D +E E++D EE E EE+E+ +EA ++E + Sbjct: 228 KAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQ 287 Query: 313 MVPGMEGKEEPGSDSGTTA 331 K++ TTA Sbjct: 288 KAAPEAKKQKVEGTEPTTA 306 Score = 30.8 bits (68), Expect = 3.3 Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 1/44 (2%) Query: 290 ENEEDEDDTEEAE-EDDEEEEEEMMVPGMEGKEEPGSDSGTTAV 332 E EED +D E +E E+D+ EE+++P +GK+ + + V Sbjct: 23 EVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVV 66 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.306 0.128 0.360 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,465,520 Number of Sequences: 37866 Number of extensions: 1373778 Number of successful extensions: 44516 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 950 Number of HSP's successfully gapped in prelim test: 711 Number of HSP's that attempted gapping in prelim test: 9988 Number of HSP's gapped (non-prelim): 14548 length of query: 546 length of database: 18,247,518 effective HSP length: 107 effective length of query: 439 effective length of database: 14,195,856 effective search space: 6231980784 effective search space used: 6231980784 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.