Guide to the Human Genome
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Search of human proteins with 4505615

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505615 paired box gene 6 isoform a [Homo sapiens]
         (422 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189083681 paired box gene 6 isoform a [Homo sapiens]               861   0.0  
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                 861   0.0  
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                 852   0.0  
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                      262   5e-70
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                259   2e-69
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                      257   2e-68
gi|207029223 paired box 7 isoform 3 [Homo sapiens]                    257   2e-68
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                 255   6e-68
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                 255   6e-68
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                  255   6e-68
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                 254   1e-67
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                 254   1e-67
gi|170784824 paired box 4 [Homo sapiens]                              244   8e-65
gi|34878709 paired box protein 2 isoform c [Homo sapiens]             239   3e-63
gi|34878716 paired box protein 2 isoform d [Homo sapiens]             235   5e-62
gi|34878701 paired box protein 2 isoform b [Homo sapiens]             235   5e-62
gi|34878699 paired box protein 2 isoform a [Homo sapiens]             229   3e-60
gi|34878703 paired box protein 2 isoform e [Homo sapiens]             229   3e-60
gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]                  227   2e-59
gi|9951920 paired box 5 [Homo sapiens]                                225   7e-59
gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]                  222   4e-58
gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]                  222   4e-58
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]                  222   4e-58
gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]                  222   4e-58
gi|197276661 paired box 1 [Homo sapiens]                              182   4e-46
gi|7242167 paired box 9 [Homo sapiens]                                181   8e-46
gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]                  173   2e-43
gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]                  173   2e-43
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...   109   4e-24
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi...   108   9e-24

>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  861 bits (2225), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
Sbjct: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQ 180
           SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQ
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQ 180

Query: 181 EGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFAR 240
           EGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFAR
Sbjct: 181 EGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFAR 240

Query: 241 ERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIP 300
           ERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIP
Sbjct: 241 ERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIP 300

Query: 301 QPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPT 360
           QPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPT
Sbjct: 301 QPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPT 360

Query: 361 SPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPR 420
           SPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPR
Sbjct: 361 SPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPR 420

Query: 421 LQ 422
           LQ
Sbjct: 421 LQ 422


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  861 bits (2225), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
Sbjct: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQ 180
           SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQ
Sbjct: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQ 180

Query: 181 EGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFAR 240
           EGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFAR
Sbjct: 181 EGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFAR 240

Query: 241 ERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIP 300
           ERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIP
Sbjct: 241 ERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIP 300

Query: 301 QPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPT 360
           QPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPT
Sbjct: 301 QPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPT 360

Query: 361 SPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPR 420
           SPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPR
Sbjct: 361 SPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPR 420

Query: 421 LQ 422
           LQ
Sbjct: 421 LQ 422


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score =  852 bits (2200), Expect = 0.0
 Identities = 422/436 (96%), Positives = 422/436 (96%), Gaps = 14/436 (3%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQ------------- 47
           MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQ             
Sbjct: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQ 60

Query: 48  -VSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 106
            VSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL
Sbjct: 61  NVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120

Query: 107 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 166
           LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT
Sbjct: 121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGT 180

Query: 167 SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE 226
           SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE
Sbjct: 181 SVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALE 240

Query: 227 KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP 286
           KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP
Sbjct: 241 KEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIP 300

Query: 287 ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP 346
           ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP
Sbjct: 301 ISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPP 360

Query: 347 VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ 406
           VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ
Sbjct: 361 VPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQ 420

Query: 407 VPGSEPDMSQYWPRLQ 422
           VPGSEPDMSQYWPRLQ
Sbjct: 421 VPGSEPDMSQYWPRLQ 436


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score =  262 bits (669), Expect = 5e-70
 Identities = 179/449 (39%), Positives = 230/449 (51%), Gaps = 81/449 (18%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRV 126
           P AIGGSKPR VATP+V  KI +YKRE P +F+WEIRDRLL +G C    +PSVSSI+RV
Sbjct: 98  PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRV 157

Query: 127 LRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGEN 186
           LR    +K++                                     +D   ++E  GE 
Sbjct: 158 LRIKFGKKEE-------------------------------------EDEADKKEDDGEK 180

Query: 187 TNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYP 235
               S +G          E SD E++  L LKRK +R+RT+FT EQ+E LEK FERTHYP
Sbjct: 181 KAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 240

Query: 236 DVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSV 295
           D++ RE LA +  L EAR+QVWFSNRRA+WR++             P   P +   +   
Sbjct: 241 DIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPP 300

Query: 296 YQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTNTYSALPPMPSFTMA 338
           YQ +P  T P ++ +   GS + R                  A  +T SA     SF+  
Sbjct: 301 YQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSY 359

Query: 339 NNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPM--GTSGTTST 394
           ++  M P  PS   +   + + P   S+ G    +  PP  Q   +  P+  G    TS 
Sbjct: 360 SDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFSISPLHGGLDSATSI 417

Query: 395 GL--------ISPGVSVPVQVPGSEPDMS 415
                     I PG S+P       P  S
Sbjct: 418 SASCSQRADSIKPGDSLPTSQAYCPPTYS 446


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score =  259 bits (663), Expect = 2e-69
 Identities = 166/409 (40%), Positives = 227/409 (55%), Gaps = 52/409 (12%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVL 127
           P AIGGSKP+V TP+V  KI +YKRE P +F+WEIRD+LL + VC  + +PSVSSI+R+L
Sbjct: 98  PGAIGGSKPKVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRIL 157

Query: 128 RNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENT 187
           R+   + ++  AD        L  +      +   +   S+ G  ++     Q       
Sbjct: 158 RSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGILSERASAPQ------- 199

Query: 188 NSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKI 247
              S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERTHYPD++ RE LA + 
Sbjct: 200 ---SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRA 255

Query: 248 DLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPISSSF--STSVYQP-- 298
            L EAR+QVWFSNRRA+WR++         N        P+ +P   ++  S + YQP  
Sbjct: 256 KLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTS 315

Query: 299 IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCML 358
           IPQ  +  SS                 +   P  PS    + +P  P      SS +  L
Sbjct: 316 IPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPSNP-----DSSSAYCL 355

Query: 359 PTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTST-GLISPGVSVPVQ 406
           P++        D++ PP   ++  +  +G   +    GL++    VP Q
Sbjct: 356 PSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQ 404


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score =  257 bits (656), Expect = 2e-68
 Identities = 179/451 (39%), Positives = 230/451 (50%), Gaps = 83/451 (18%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPS--VSSIN 124
           P AIGGSKPR VATP+V  KI +YKRE P +F+WEIRDRLL +G C    +PS  VSSI+
Sbjct: 98  PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSIS 157

Query: 125 RVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGG 184
           RVLR    +K++                                     +D   ++E  G
Sbjct: 158 RVLRIKFGKKEE-------------------------------------EDEADKKEDDG 180

Query: 185 ENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTH 233
           E     S +G          E SD E++  L LKRK +R+RT+FT EQ+E LEK FERTH
Sbjct: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240

Query: 234 YPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFST 293
           YPD++ RE LA +  L EAR+QVWFSNRRA+WR++             P   P +   + 
Sbjct: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300

Query: 294 SVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTNTYSALPPMPSFT 336
             YQ +P  T P ++ +   GS + R                  A  +T SA     SF+
Sbjct: 301 PPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFS 359

Query: 337 MANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPM--GTSGTT 392
             ++  M P  PS   +   + + P   S+ G    +  PP  Q   +  P+  G    T
Sbjct: 360 SYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFSISPLHGGLDSAT 417

Query: 393 STGL--------ISPGVSVPVQVPGSEPDMS 415
           S           I PG S+P       P  S
Sbjct: 418 SISASCSQRADSIKPGDSLPTSQAYCPPTYS 448


>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score =  257 bits (656), Expect = 2e-68
 Identities = 179/451 (39%), Positives = 230/451 (50%), Gaps = 83/451 (18%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPS--VSSIN 124
           P AIGGSKPR VATP+V  KI +YKRE P +F+WEIRDRLL +G C    +PS  VSSI+
Sbjct: 98  PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSIS 157

Query: 125 RVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGG 184
           RVLR    +K++                                     +D   ++E  G
Sbjct: 158 RVLRIKFGKKEE-------------------------------------EDEADKKEDDG 180

Query: 185 ENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTH 233
           E     S +G          E SD E++  L LKRK +R+RT+FT EQ+E LEK FERTH
Sbjct: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240

Query: 234 YPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFST 293
           YPD++ RE LA +  L EAR+QVWFSNRRA+WR++             P   P +   + 
Sbjct: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300

Query: 294 SVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTNTYSALPPMPSFT 336
             YQ +P  T P ++ +   GS + R                  A  +T SA     SF+
Sbjct: 301 PPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFS 359

Query: 337 MANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPM--GTSGTT 392
             ++  M P  PS   +   + + P   S+ G    +  PP  Q   +  P+  G    T
Sbjct: 360 SYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFSISPLHGGLDSAT 417

Query: 393 STGL--------ISPGVSVPVQVPGSEPDMS 415
           S           I PG S+P       P  S
Sbjct: 418 SISASCSQRADSIKPGDSLPTSQAYCPPTYS 448


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score =  255 bits (651), Expect = 6e-68
 Identities = 166/410 (40%), Positives = 227/410 (55%), Gaps = 53/410 (12%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRV 126
           P AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC  + +PSVSSI+R+
Sbjct: 98  PGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRI 157

Query: 127 LRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGEN 186
           LR+   + ++  AD        L  +      +   +   S+ G  ++     Q      
Sbjct: 158 LRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGILSERASAPQ------ 200

Query: 187 TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAK 246
               S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERTHYPD++ RE LA +
Sbjct: 201 ----SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 255

Query: 247 IDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPISSSF--STSVYQP- 298
             L EAR+QVWFSNRRA+WR++         N        P+ +P   ++  S + YQP 
Sbjct: 256 AKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPT 315

Query: 299 -IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCM 357
            IPQ  +  SS                 +   P  PS    + +P  P      SS +  
Sbjct: 316 SIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPSNP-----DSSSAYC 355

Query: 358 LPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTST-GLISPGVSVPVQ 406
           LP++        D++ PP   ++  +  +G   +    GL++    VP Q
Sbjct: 356 LPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQ 405


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score =  255 bits (651), Expect = 6e-68
 Identities = 166/410 (40%), Positives = 227/410 (55%), Gaps = 53/410 (12%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRV 126
           P AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC  + +PSVSSI+R+
Sbjct: 98  PGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRI 157

Query: 127 LRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGEN 186
           LR+   + ++  AD        L  +      +   +   S+ G  ++     Q      
Sbjct: 158 LRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGILSERASAPQ------ 200

Query: 187 TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAK 246
               S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERTHYPD++ RE LA +
Sbjct: 201 ----SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 255

Query: 247 IDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPISSSF--STSVYQP- 298
             L EAR+QVWFSNRRA+WR++         N        P+ +P   ++  S + YQP 
Sbjct: 256 AKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPT 315

Query: 299 -IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCM 357
            IPQ  +  SS                 +   P  PS    + +P  P      SS +  
Sbjct: 316 SIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPSNP-----DSSSAYC 355

Query: 358 LPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTST-GLISPGVSVPVQ 406
           LP++        D++ PP   ++  +  +G   +    GL++    VP Q
Sbjct: 356 LPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQ 405


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score =  255 bits (651), Expect = 6e-68
 Identities = 166/410 (40%), Positives = 227/410 (55%), Gaps = 53/410 (12%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRV 126
           P AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC  + +PSVSSI+R+
Sbjct: 98  PGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRI 157

Query: 127 LRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGEN 186
           LR+   + ++  AD        L  +      +   +   S+ G  ++     Q      
Sbjct: 158 LRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGILSERASAPQ------ 200

Query: 187 TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAK 246
               S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERTHYPD++ RE LA +
Sbjct: 201 ----SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 255

Query: 247 IDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPISSSF--STSVYQP- 298
             L EAR+QVWFSNRRA+WR++         N        P+ +P   ++  S + YQP 
Sbjct: 256 AKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPT 315

Query: 299 -IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCM 357
            IPQ  +  SS                 +   P  PS    + +P  P      SS +  
Sbjct: 316 SIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPSNP-----DSSSAYC 355

Query: 358 LPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTST-GLISPGVSVPVQ 406
           LP++        D++ PP   ++  +  +G   +    GL++    VP Q
Sbjct: 356 LPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQ 405


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score =  254 bits (649), Expect = 1e-67
 Identities = 160/378 (42%), Positives = 214/378 (56%), Gaps = 52/378 (13%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRV 126
           P AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC  + +PSVSSI+R+
Sbjct: 98  PGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRI 157

Query: 127 LRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGEN 186
           LR+   + ++  AD        L  +      +   +   S+ G  ++     Q      
Sbjct: 158 LRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGILSERASAPQ------ 200

Query: 187 TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAK 246
               S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERTHYPD++ RE LA +
Sbjct: 201 ----SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 255

Query: 247 IDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPISSSF--STSVYQP- 298
             L EAR+QVWFSNRRA+WR++         N        P+ +P   ++  S + YQP 
Sbjct: 256 AKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPT 315

Query: 299 -IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCM 357
            IPQ  +  SS                 +   P  PS    + +P  P      SS +  
Sbjct: 316 SIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPSNP-----DSSSAYC 355

Query: 358 LPTSPSVNGRSYDTYTPP 375
           LP++        D++ PP
Sbjct: 356 LPSTRHGFSSYTDSFVPP 373


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score =  254 bits (649), Expect = 1e-67
 Identities = 160/378 (42%), Positives = 214/378 (56%), Gaps = 52/378 (13%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRV 126
           P AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC  + +PSVSSI+R+
Sbjct: 98  PGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRI 157

Query: 127 LRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGEN 186
           LR+   + ++  AD        L  +      +   +   S+ G  ++     Q      
Sbjct: 158 LRSKFGKGEEEEAD--------LERKEAEESEKKAKH---SIDGILSERASAPQ------ 200

Query: 187 TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAK 246
               S  G D D ++  L LKRK +R+RT+FT EQ+E LE+ FERTHYPD++ RE LA +
Sbjct: 201 ----SDEGSDID-SEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 255

Query: 247 IDLPEARIQVWFSNRRAKWRREEKLR-----NQRRQASNTPSHIPISSSF--STSVYQP- 298
             L EAR+QVWFSNRRA+WR++         N        P+ +P   ++  S + YQP 
Sbjct: 256 AKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPT 315

Query: 299 -IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCM 357
            IPQ  +  SS                 +   P  PS    + +P  P      SS +  
Sbjct: 316 SIPQAVSDPSS---------------TVHRPQPLPPSTVHQSTIPSNP-----DSSSAYC 355

Query: 358 LPTSPSVNGRSYDTYTPP 375
           LP++        D++ PP
Sbjct: 356 LPSTRHGFSSYTDSFVPP 373


>gi|170784824 paired box 4 [Homo sapiens]
          Length = 343

 Score =  244 bits (624), Expect = 8e-65
 Identities = 139/269 (51%), Positives = 166/269 (61%), Gaps = 49/269 (18%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           +NQLGG+FVNGRPLP  TRQ+IV LA SG RPCDISRIL+VSNGCVSKILGRYY TG + 
Sbjct: 1   MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE 60

Query: 68  PRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVL 127
           P+ IGGSKPR+ATP VV++IAQ K ECP++FAWEI+ +L +EG+CT D  PSVSSINRVL
Sbjct: 61  PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL 120

Query: 128 RNLASEKQQMGADGMYDKL----RMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGG 183
           R L  E Q +    +         +L   +GS  T  G +PGT                 
Sbjct: 121 RAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGS-ETPRGTHPGTG---------------- 162

Query: 184 GENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERL 243
                                       RNRT F+  Q EALEKEF+R  YPD  AR +L
Sbjct: 163 ---------------------------HRNRTIFSPSQAEALEKEFQRGQYPDSVARGKL 195

Query: 244 AAKIDLPEARIQVWFSNRRAKWRREEKLR 272
           A    LPE  ++VWFSNRRAKWRR+EKL+
Sbjct: 196 ATATSLPEDTVRVWFSNRRAKWRRQEKLK 224


>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
          Length = 396

 Score =  239 bits (611), Expect = 3e-63
 Identities = 165/401 (41%), Positives = 211/401 (52%), Gaps = 42/401 (10%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVP--GQPTQDGCQ 178
           SSINR++R    +      DG            G+  T PG    T VP    P      
Sbjct: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HTIVPSTASPPVSSAS 178

Query: 179 QQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLKRKLQRNRTSFTQEQ 221
               G  + N I     SNGE    D D         ++Q  +   RK  R  T FTQ+Q
Sbjct: 179 NDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQ 237

Query: 222 IEALEKEFERTHYPDVF-ARERLAA----KIDLPEARIQVWFSNRRAKWRREEKLRNQRR 276
           +EAL++ FER  YPDVF A E + +    +  LP     +             +L +   
Sbjct: 238 LEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVS 297

Query: 277 QASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFT 336
                P       + +T    P   P T   S+ + ++ G    A     S+L   P   
Sbjct: 298 GTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPEAAVGPSSSLMSKPGRK 357

Query: 337 MANNLP-MQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPH 376
           +A   P +QP   S  ++ +    T P+   R  D+ TPP+
Sbjct: 358 LAEVPPCVQPTGASSPATRTATPSTRPTT--RLGDSATPPY 396


>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
          Length = 408

 Score =  235 bits (600), Expect = 5e-62
 Identities = 137/257 (53%), Positives = 162/257 (63%), Gaps = 34/257 (13%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVP--GQPTQDGCQ 178
           SSINR++R    +      DG            G+  T PG    T VP    P      
Sbjct: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HTIVPSTASPPVSSAS 178

Query: 179 QQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLKRKLQRNRTSFTQEQ 221
               G  + N I     SNGE    D D         ++Q  +   RK  R  T FTQ+Q
Sbjct: 179 NDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQ 237

Query: 222 IEALEKEFERTHYPDVF 238
           +EAL++ FER  YPDVF
Sbjct: 238 LEALDRVFERPSYPDVF 254


>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
          Length = 393

 Score =  235 bits (600), Expect = 5e-62
 Identities = 137/257 (53%), Positives = 162/257 (63%), Gaps = 34/257 (13%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVP--GQPTQDGCQ 178
           SSINR++R    +      DG            G+  T PG    T VP    P      
Sbjct: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPG---HTIVPSTASPPVSSAS 178

Query: 179 QQEGGGENTNSI----SSNGE----DSD---------EAQMRLQLKRKLQRNRTSFTQEQ 221
               G  + N I     SNGE    D D         ++Q  +   RK  R  T FTQ+Q
Sbjct: 179 NDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADT-FTQQQ 237

Query: 222 IEALEKEFERTHYPDVF 238
           +EAL++ FER  YPDVF
Sbjct: 238 LEALDRVFERPSYPDVF 254


>gi|34878699 paired box protein 2 isoform a [Homo sapiens]
          Length = 416

 Score =  229 bits (585), Expect = 3e-60
 Identities = 134/277 (48%), Positives = 165/277 (59%), Gaps = 51/277 (18%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGW--YPGTSVP--------- 169
           SSINR++R    +      DG            G+  T PG    P T+ P         
Sbjct: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPGHTIVPSTASPPVSSASNDP 181

Query: 170 ----------GQPTQDGCQQQ-------------EGGGE-----NTNSISSNGEDSDEAQ 201
                     G P  +G +++              GGG          +S     + ++Q
Sbjct: 182 VGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQ 241

Query: 202 MRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVF 238
             +   RK  R  T FTQ+Q+EAL++ FER  YPDVF
Sbjct: 242 SGVDSLRKHLRADT-FTQQQLEALDRVFERPSYPDVF 277


>gi|34878703 paired box protein 2 isoform e [Homo sapiens]
          Length = 431

 Score =  229 bits (585), Expect = 3e-60
 Identities = 134/277 (48%), Positives = 165/277 (59%), Gaps = 51/277 (18%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           M   H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 13  MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY 72

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+EG+C ND +PSV
Sbjct: 73  YETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSV 132

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGW--YPGTSVP--------- 169
           SSINR++R    +      DG            G+  T PG    P T+ P         
Sbjct: 133 SSINRIIRTKVQQPFHPTPDG-----------AGTGVTAPGHTIVPSTASPPVSSASNDP 181

Query: 170 ----------GQPTQDGCQQQ-------------EGGGE-----NTNSISSNGEDSDEAQ 201
                     G P  +G +++              GGG          +S     + ++Q
Sbjct: 182 VGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQ 241

Query: 202 MRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVF 238
             +   RK  R  T FTQ+Q+EAL++ FER  YPDVF
Sbjct: 242 SGVDSLRKHLRADT-FTQQQLEALDRVFERPSYPDVF 277


>gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]
          Length = 450

 Score =  227 bits (578), Expect = 2e-59
 Identities = 154/411 (37%), Positives = 206/411 (50%), Gaps = 68/411 (16%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           +++ H G+NQLGG FVNGRPLP+  RQ+IV+LAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 6   IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRY 65

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSIRP  IGGSKP+VATP+VV KI  YKR+ P++FAWEIRDRLL+EGVC ND +PSV
Sbjct: 66  YETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSV 125

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSV--PGQPTQDGCQ 178
           SSINR++R    +   +  D       +  G T          P ++V  P  P  D   
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSSAVTPPESPQSDSLG 177

Query: 179 QQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------RT-SFTQEQIEALE 226
                    G     S     +DSD+   RL +  +   +      RT +F+Q  +E LE
Sbjct: 178 STYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLE 237

Query: 227 KEFERTHYPDVFAR------ERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASN 280
             FER HYP+ +A       E+    + L  + +                      +A+ 
Sbjct: 238 CPFERQHYPEAYASPSHTKGEQGLYPLPLLNSTL-------------------DDGKATL 278

Query: 281 TPSHIPISSSFST-SVYQPIPQPTTPV-----------SSFTSGSMLGRTDTALTNTYSA 328
           TPS+ P+  + ST   Y  +  P +P            SS T  S+       L    S 
Sbjct: 279 TPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSG 338

Query: 329 LPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQT 379
           +PP  +F  A ++  Q    +  S    + PT P           PPH+ T
Sbjct: 339 VPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGY---------PPHIPT 380


>gi|9951920 paired box 5 [Homo sapiens]
          Length = 391

 Score =  225 bits (573), Expect = 7e-59
 Identities = 125/248 (50%), Positives = 158/248 (63%), Gaps = 22/248 (8%)

Query: 2   QNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYY 61
           +  H GVNQLGGVFVNGRPLPD  RQ+IVELAH G RPCDISR L+VS+GCVSKILGRYY
Sbjct: 14  RTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYY 73

Query: 62  ETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVS 121
           ETGSI+P  IGGSKP+VATP+VV KIA+YKR+ P++FAWEIRDRLL+E VC ND +PSVS
Sbjct: 74  ETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVS 133

Query: 122 SINRVLRN---------LASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQP 172
           SINR++R          + +    + + G   ++  ++  +           G + P   
Sbjct: 134 SINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSAD 193

Query: 173 TQDGCQQQEGGGEN--TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFE 230
           T    ++ EG  E+   N  S  G D    QMR  L          FTQ+Q+E L++ FE
Sbjct: 194 TNKR-KRDEGIQESPVPNGHSLPGRDFLRKQMRGDL----------FTQQQLEVLDRVFE 242

Query: 231 RTHYPDVF 238
           R HY D+F
Sbjct: 243 RQHYSDIF 250


>gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]
          Length = 321

 Score =  222 bits (566), Expect = 4e-58
 Identities = 123/253 (48%), Positives = 156/253 (61%), Gaps = 22/253 (8%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           +++ H G+NQLGG FVNGRPLP+  RQ+IV+LAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 6   IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRY 65

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSIRP  IGGSKP+VATP+VV KI  YKR+ P++FAWEIRDRLL+EGVC ND +PSV
Sbjct: 66  YETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSV 125

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSV--PGQPTQDGCQ 178
           SSINR++R    +   +  D       +  G T          P ++V  P  P  D   
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSSAVTPPESPQSDSLG 177

Query: 179 QQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------RT-SFTQEQIEALE 226
                    G     S     +DSD+   RL +  +   +      RT +F+Q  +E LE
Sbjct: 178 STYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLE 237

Query: 227 KEFERTHYPDVFA 239
             FER HYP+ +A
Sbjct: 238 CPFERQHYPEAYA 250


>gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]
          Length = 287

 Score =  222 bits (566), Expect = 4e-58
 Identities = 123/253 (48%), Positives = 156/253 (61%), Gaps = 22/253 (8%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           +++ H G+NQLGG FVNGRPLP+  RQ+IV+LAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 6   IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRY 65

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSIRP  IGGSKP+VATP+VV KI  YKR+ P++FAWEIRDRLL+EGVC ND +PSV
Sbjct: 66  YETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSV 125

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSV--PGQPTQDGCQ 178
           SSINR++R    +   +  D       +  G T          P ++V  P  P  D   
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSSAVTPPESPQSDSLG 177

Query: 179 QQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------RT-SFTQEQIEALE 226
                    G     S     +DSD+   RL +  +   +      RT +F+Q  +E LE
Sbjct: 178 STYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLE 237

Query: 227 KEFERTHYPDVFA 239
             FER HYP+ +A
Sbjct: 238 CPFERQHYPEAYA 250


>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
          Length = 398

 Score =  222 bits (566), Expect = 4e-58
 Identities = 123/253 (48%), Positives = 156/253 (61%), Gaps = 22/253 (8%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           +++ H G+NQLGG FVNGRPLP+  RQ+IV+LAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 6   IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRY 65

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSIRP  IGGSKP+VATP+VV KI  YKR+ P++FAWEIRDRLL+EGVC ND +PSV
Sbjct: 66  YETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSV 125

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSV--PGQPTQDGCQ 178
           SSINR++R    +   +  D       +  G T          P ++V  P  P  D   
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSSAVTPPESPQSDSLG 177

Query: 179 QQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------RT-SFTQEQIEALE 226
                    G     S     +DSD+   RL +  +   +      RT +F+Q  +E LE
Sbjct: 178 STYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLE 237

Query: 227 KEFERTHYPDVFA 239
             FER HYP+ +A
Sbjct: 238 CPFERQHYPEAYA 250


>gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
          Length = 387

 Score =  222 bits (566), Expect = 4e-58
 Identities = 123/253 (48%), Positives = 156/253 (61%), Gaps = 22/253 (8%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           +++ H G+NQLGG FVNGRPLP+  RQ+IV+LAH G RPCDISR L+VS+GCVSKILGRY
Sbjct: 6   IRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRY 65

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
           YETGSIRP  IGGSKP+VATP+VV KI  YKR+ P++FAWEIRDRLL+EGVC ND +PSV
Sbjct: 66  YETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSV 125

Query: 121 SSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSV--PGQPTQDGCQ 178
           SSINR++R    +   +  D       +  G T          P ++V  P  P  D   
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHT--------LIPSSAVTPPESPQSDSLG 177

Query: 179 QQEG-----GGENTNSISSNGEDSDEAQMRLQLKRKLQRN------RT-SFTQEQIEALE 226
                    G     S     +DSD+   RL +  +   +      RT +F+Q  +E LE
Sbjct: 178 STYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLE 237

Query: 227 KEFERTHYPDVFA 239
             FER HYP+ +A
Sbjct: 238 CPFERQHYPEAYA 250


>gi|197276661 paired box 1 [Homo sapiens]
          Length = 534

 Score =  182 bits (463), Expect = 4e-46
 Identities = 92/138 (66%), Positives = 106/138 (76%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           M+ ++  VNQLGGVFVNGRPLP++ R +IVELA  G RPCDISR L+VS+GCVSKIL RY
Sbjct: 95  MEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARY 154

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
            ETGSI P AIGGSKPRV TP VV  I  YK+  P IFAWEIRDRLL++GVC   N+PSV
Sbjct: 155 NETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSV 214

Query: 121 SSINRVLRNLASEKQQMG 138
           SSI+R+LRN      Q G
Sbjct: 215 SSISRILRNKIGSLAQPG 232


>gi|7242167 paired box 9 [Homo sapiens]
          Length = 341

 Score =  181 bits (460), Expect = 8e-46
 Identities = 92/138 (66%), Positives = 105/138 (76%)

Query: 1   MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY 60
           M+ +   VNQLGGVFVNGRPLP++ R +IVELA  G RPCDISR L+VS+GCVSKIL RY
Sbjct: 1   MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARY 60

Query: 61  YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV 120
            ETGSI P AIGGSKPRV TP VV  I  YK+  P IFAWEIRDRLL++GVC   N+PSV
Sbjct: 61  NETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSV 120

Query: 121 SSINRVLRNLASEKQQMG 138
           SSI+R+LRN      Q G
Sbjct: 121 SSISRILRNKIGNLAQQG 138


>gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]
          Length = 206

 Score =  173 bits (439), Expect = 2e-43
 Identities = 86/134 (64%), Positives = 106/134 (79%), Gaps = 1/134 (0%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRV 126
           P AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC  + +PSVSSI+R+
Sbjct: 98  PGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRI 157

Query: 127 LRNLASEKQQMGAD 140
           LR+   + ++  AD
Sbjct: 158 LRSKFGKGEEEEAD 171


>gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]
          Length = 215

 Score =  173 bits (439), Expect = 2e-43
 Identities = 86/134 (64%), Positives = 106/134 (79%), Gaps = 1/134 (0%)

Query: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97

Query: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRV 126
           P AIGGSKP+ V TP+V  KI +YKRE P +F+WEIRD+LL + VC  + +PSVSSI+R+
Sbjct: 98  PGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRI 157

Query: 127 LRNLASEKQQMGAD 140
           LR+   + ++  AD
Sbjct: 158 LRSKFGKGEEEEAD 171


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score =  109 bits (273), Expect = 4e-24
 Identities = 69/164 (42%), Positives = 90/164 (54%), Gaps = 12/164 (7%)

Query: 205 QLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAK 264
           Q K+K +RNRT+FT  Q+  LE+ FE++HYPDV++RE LA K++LPE R+QVWF NRRAK
Sbjct: 131 QPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAK 190

Query: 265 WRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTN 324
           WRR+EKL     +  ++P       SFS S     P  T        GS  G    AL  
Sbjct: 191 WRRQEKLEVSSMKLQDSP-----LLSFSRSP----PSATLSPLGAGPGSGGGPAGGALPL 241

Query: 325 TYSALPPMP--SFTMANNLP-MQPPVPSQTSSYSCMLPTSPSVN 365
                PP+P    T   +LP   PP  S  +SY+   P  P +N
Sbjct: 242 ESWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPPPPFLN 285


>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
           sapiens]
          Length = 245

 Score =  108 bits (270), Expect = 9e-24
 Identities = 66/159 (41%), Positives = 91/159 (57%), Gaps = 14/159 (8%)

Query: 187 TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAK 246
           T+   +  +D+D+     + KRK +RNRT+F   Q++ALE+ FERTHYPD F RE LA +
Sbjct: 71  TSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARR 130

Query: 247 IDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPI-PQPTTP 305
           ++L EAR+QVWF NRRAK+RR E+     + AS   S+    S   T+V QPI P+P   
Sbjct: 131 VNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSY----SGDVTAVEQPIVPRPAPR 186

Query: 306 VSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQ 344
            + + S            + YSA+    S T ANN P Q
Sbjct: 187 PTDYLS--------WGTASPYSAMATY-SATCANNSPAQ 216


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,464,370
Number of Sequences: 37866
Number of extensions: 957231
Number of successful extensions: 4624
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 308
Number of HSP's successfully gapped in prelim test: 225
Number of HSP's that attempted gapping in prelim test: 3602
Number of HSP's gapped (non-prelim): 1062
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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