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Search of human proteins with 4503861
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
(462 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 935 0.0
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 659 0.0
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 659 0.0
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 647 0.0
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 642 0.0
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 642 0.0
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 642 0.0
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 642 0.0
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 642 0.0
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 642 0.0
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 642 0.0
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 509 e-144
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 479 e-135
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 375 e-104
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 365 e-101
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 365 e-101
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 349 3e-96
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform... 344 1e-94
gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p... 304 1e-82
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 280 2e-75
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 278 7e-75
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 275 8e-74
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 275 8e-74
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 275 8e-74
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 274 1e-73
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 273 2e-73
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 272 5e-73
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 271 1e-72
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 271 1e-72
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 266 2e-71
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 935 bits (2416), Expect = 0.0
Identities = 462/462 (100%), Positives = 462/462 (100%)
Query: 1 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY 60
MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
Sbjct: 1 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY 60
Query: 61 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL 120
DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
Sbjct: 61 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL 120
Query: 121 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF 180
NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
Sbjct: 121 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF 180
Query: 181 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS 240
PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
Sbjct: 181 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS 240
Query: 241 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM 300
TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
Sbjct: 241 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM 300
Query: 301 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA 360
TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
Sbjct: 301 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA 360
Query: 361 KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN 420
KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN
Sbjct: 361 KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN 420
Query: 421 SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK 462
SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
Sbjct: 421 SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK 462
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 659 bits (1701), Expect = 0.0
Identities = 323/419 (77%), Positives = 359/419 (85%), Gaps = 5/419 (1%)
Query: 39 KDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDV 98
+DE +NITIFTRILD LLDGYDNRLRPGLG+ IT+V T+IYVTSFGPVSDT+MEYTIDV
Sbjct: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
Query: 99 FFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDD 158
FFRQ WKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR++DD
Sbjct: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
Query: 159 GTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAED 218
GTLLYTMRLT+ AECPM LEDFPMDAH+CPLKFGSYAY SEV Y+WT ++ SV VA D
Sbjct: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
Query: 219 GSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 278
GSRLNQY L+GQ++G E I +STGEYT+MTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 279 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 338
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 339 ATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQ--TPAG 396
ATVNYFTKRGWAWDGK + K +K +I N NA+ ++ PN+ K+ +
Sbjct: 332 ATVNYFTKRGWAWDGKSVVNDKKKEKASVMIQN---NAYAVAVANYAPNLSKDPVLSTIS 388
Query: 397 TSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVI 455
S TT K E K +E+KKT+NS+SKID+MSRIVFPVLFGTFNLVYWATYLNREPV+
Sbjct: 389 KSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 659 bits (1701), Expect = 0.0
Identities = 323/419 (77%), Positives = 359/419 (85%), Gaps = 5/419 (1%)
Query: 39 KDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDV 98
+DE +NITIFTRILD LLDGYDNRLRPGLG+ IT+V T+IYVTSFGPVSDT+MEYTIDV
Sbjct: 32 EDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDV 91
Query: 99 FFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDD 158
FFRQ WKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR++DD
Sbjct: 92 FFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDD 151
Query: 159 GTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAED 218
GTLLYTMRLT+ AECPM LEDFPMDAH+CPLKFGSYAY SEV Y+WT ++ SV VA D
Sbjct: 152 GTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPD 211
Query: 219 GSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 278
GSRLNQY L+GQ++G E I +STGEYT+MTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS
Sbjct: 212 GSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVS 271
Query: 279 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 338
FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF
Sbjct: 272 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 331
Query: 339 ATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQ--TPAG 396
ATVNYFTKRGWAWDGK + K +K +I N NA+ ++ PN+ K+ +
Sbjct: 332 ATVNYFTKRGWAWDGKSVVNDKKKEKASVMIQN---NAYAVAVANYAPNLSKDPVLSTIS 388
Query: 397 TSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVI 455
S TT K E K +E+KKT+NS+SKID+MSRIVFPVLFGTFNLVYWATYLNREPV+
Sbjct: 389 KSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 647 bits (1669), Expect = 0.0
Identities = 321/441 (72%), Positives = 357/441 (80%), Gaps = 12/441 (2%)
Query: 29 GFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVS 88
G S + D++ DNITIFTRILD LLDGYDNRLRPGLG+ +T+V+TDIYVTSFGPVS
Sbjct: 47 GLSPKHAPDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVS 106
Query: 89 DTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTT 148
DT+MEYTIDVFFRQ+W DERL+F GPM+ LPLNNLLASKIWTPDTFFHNGKKS+AHNMTT
Sbjct: 107 DTDMEYTIDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTT 166
Query: 149 PNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNG 208
PNKLLRL D+GTLLYTMRLTI AECPM LEDFPMD HACPLKFGSYAY +EVVY WT G
Sbjct: 167 PNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLG 226
Query: 209 STKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPC 268
KSV VA+DGSRLNQY L+G VGTE I +STGEY +MT HFHLKRKIGYFVIQTYLPC
Sbjct: 227 KNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPC 286
Query: 269 IMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCY 328
IMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCY
Sbjct: 287 IMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCY 346
Query: 329 AFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREVI-LNKSTNAFTTGKMSHPPN 387
AFVFSALIEFATVNYFTKR WAW+GKK EA ++KKK K++ F ++P N
Sbjct: 347 AFVFSALIEFATVNYFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPIN 406
Query: 388 IPKEQ--------TPAGTSNTTSVSVKPSEEKTSES---KKTYNSISKIDKMSRIVFPVL 436
+ K+ S+T ++ P +S KTYNS+SK+DK+SRI+FPVL
Sbjct: 407 LAKDTEFSTISKGAAPSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVL 466
Query: 437 FGTFNLVYWATYLNREPVIKG 457
F FNLVYWATY+NRE IKG
Sbjct: 467 FAIFNLVYWATYVNRESAIKG 487
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 642 bits (1656), Expect = 0.0
Identities = 319/424 (75%), Positives = 358/424 (84%), Gaps = 7/424 (1%)
Query: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96
S++DE DN T+FTRILD LLDGYDNRLRPGLGER+T+V+TDI+VTSFGPVSD +MEYTI
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTI 89
Query: 97 DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156
DVFFRQSWKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR+
Sbjct: 90 DVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT 149
Query: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216
+DGTLLYTMRLT+ AECPM LEDFPMDAHACPLKFGSYAY +EVVY WT +SVVVA
Sbjct: 150 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVA 209
Query: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276
EDGSRLNQY L+GQTV + + +STGEY +MT HFHLKRKIGYFVIQTYLPCIMTVILSQ
Sbjct: 210 EDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 269
Query: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336
VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI
Sbjct: 270 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 329
Query: 337 EFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQ 392
EFATVNYFTKRG+AWDGK + K KK ++ ++ K+ N + S+ PN+ P
Sbjct: 330 EFATVNYFTKRGYAWDGKSVV-PEKPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLA 387
Query: 393 TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452
T A ++ VKP E K E KKT+NS+SKID++SRI FP+LFG FNLVYWATYLNRE
Sbjct: 388 TIAKSATIEPKEVKP-ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
Query: 453 PVIK 456
P +K
Sbjct: 447 PQLK 450
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 642 bits (1656), Expect = 0.0
Identities = 319/424 (75%), Positives = 358/424 (84%), Gaps = 7/424 (1%)
Query: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96
S++DE DN T+FTRILD LLDGYDNRLRPGLGER+T+V+TDI+VTSFGPVSD +MEYTI
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTI 89
Query: 97 DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156
DVFFRQSWKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR+
Sbjct: 90 DVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT 149
Query: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216
+DGTLLYTMRLT+ AECPM LEDFPMDAHACPLKFGSYAY +EVVY WT +SVVVA
Sbjct: 150 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVA 209
Query: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276
EDGSRLNQY L+GQTV + + +STGEY +MT HFHLKRKIGYFVIQTYLPCIMTVILSQ
Sbjct: 210 EDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 269
Query: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336
VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI
Sbjct: 270 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 329
Query: 337 EFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQ 392
EFATVNYFTKRG+AWDGK + K KK ++ ++ K+ N + S+ PN+ P
Sbjct: 330 EFATVNYFTKRGYAWDGKSVV-PEKPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLA 387
Query: 393 TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452
T A ++ VKP E K E KKT+NS+SKID++SRI FP+LFG FNLVYWATYLNRE
Sbjct: 388 TIAKSATIEPKEVKP-ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
Query: 453 PVIK 456
P +K
Sbjct: 447 PQLK 450
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 642 bits (1656), Expect = 0.0
Identities = 319/424 (75%), Positives = 358/424 (84%), Gaps = 7/424 (1%)
Query: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96
S++DE DN T+FTRILD LLDGYDNRLRPGLGER+T+V+TDI+VTSFGPVSD +MEYTI
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTI 89
Query: 97 DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156
DVFFRQSWKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR+
Sbjct: 90 DVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT 149
Query: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216
+DGTLLYTMRLT+ AECPM LEDFPMDAHACPLKFGSYAY +EVVY WT +SVVVA
Sbjct: 150 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVA 209
Query: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276
EDGSRLNQY L+GQTV + + +STGEY +MT HFHLKRKIGYFVIQTYLPCIMTVILSQ
Sbjct: 210 EDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 269
Query: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336
VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI
Sbjct: 270 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 329
Query: 337 EFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQ 392
EFATVNYFTKRG+AWDGK + K KK ++ ++ K+ N + S+ PN+ P
Sbjct: 330 EFATVNYFTKRGYAWDGKSVV-PEKPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLA 387
Query: 393 TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452
T A ++ VKP E K E KKT+NS+SKID++SRI FP+LFG FNLVYWATYLNRE
Sbjct: 388 TIAKSATIEPKEVKP-ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
Query: 453 PVIK 456
P +K
Sbjct: 447 PQLK 450
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 642 bits (1656), Expect = 0.0
Identities = 319/424 (75%), Positives = 358/424 (84%), Gaps = 7/424 (1%)
Query: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96
S++DE DN T+FTRILD LLDGYDNRLRPGLGER+T+V+TDI+VTSFGPVSD +MEYTI
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTI 89
Query: 97 DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156
DVFFRQSWKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR+
Sbjct: 90 DVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT 149
Query: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216
+DGTLLYTMRLT+ AECPM LEDFPMDAHACPLKFGSYAY +EVVY WT +SVVVA
Sbjct: 150 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVA 209
Query: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276
EDGSRLNQY L+GQTV + + +STGEY +MT HFHLKRKIGYFVIQTYLPCIMTVILSQ
Sbjct: 210 EDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 269
Query: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336
VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI
Sbjct: 270 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 329
Query: 337 EFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQ 392
EFATVNYFTKRG+AWDGK + K KK ++ ++ K+ N + S+ PN+ P
Sbjct: 330 EFATVNYFTKRGYAWDGKSVV-PEKPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLA 387
Query: 393 TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452
T A ++ VKP E K E KKT+NS+SKID++SRI FP+LFG FNLVYWATYLNRE
Sbjct: 388 TIAKSATIEPKEVKP-ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
Query: 453 PVIK 456
P +K
Sbjct: 447 PQLK 450
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 642 bits (1656), Expect = 0.0
Identities = 319/424 (75%), Positives = 358/424 (84%), Gaps = 7/424 (1%)
Query: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96
S++DE DN T+FTRILD LLDGYDNRLRPGLGER+T+V+TDI+VTSFGPVSD +MEYTI
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTI 89
Query: 97 DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156
DVFFRQSWKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR+
Sbjct: 90 DVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT 149
Query: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216
+DGTLLYTMRLT+ AECPM LEDFPMDAHACPLKFGSYAY +EVVY WT +SVVVA
Sbjct: 150 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVA 209
Query: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276
EDGSRLNQY L+GQTV + + +STGEY +MT HFHLKRKIGYFVIQTYLPCIMTVILSQ
Sbjct: 210 EDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 269
Query: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336
VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI
Sbjct: 270 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 329
Query: 337 EFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQ 392
EFATVNYFTKRG+AWDGK + K KK ++ ++ K+ N + S+ PN+ P
Sbjct: 330 EFATVNYFTKRGYAWDGKSVV-PEKPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLA 387
Query: 393 TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452
T A ++ VKP E K E KKT+NS+SKID++SRI FP+LFG FNLVYWATYLNRE
Sbjct: 388 TIAKSATIEPKEVKP-ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
Query: 453 PVIK 456
P +K
Sbjct: 447 PQLK 450
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 642 bits (1656), Expect = 0.0
Identities = 319/424 (75%), Positives = 358/424 (84%), Gaps = 7/424 (1%)
Query: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96
S++DE DN T+FTRILD LLDGYDNRLRPGLGER+T+V+TDI+VTSFGPVSD +MEYTI
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTI 89
Query: 97 DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156
DVFFRQSWKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR+
Sbjct: 90 DVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT 149
Query: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216
+DGTLLYTMRLT+ AECPM LEDFPMDAHACPLKFGSYAY +EVVY WT +SVVVA
Sbjct: 150 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVA 209
Query: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276
EDGSRLNQY L+GQTV + + +STGEY +MT HFHLKRKIGYFVIQTYLPCIMTVILSQ
Sbjct: 210 EDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 269
Query: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336
VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI
Sbjct: 270 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 329
Query: 337 EFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQ 392
EFATVNYFTKRG+AWDGK + K KK ++ ++ K+ N + S+ PN+ P
Sbjct: 330 EFATVNYFTKRGYAWDGKSVV-PEKPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLA 387
Query: 393 TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452
T A ++ VKP E K E KKT+NS+SKID++SRI FP+LFG FNLVYWATYLNRE
Sbjct: 388 TIAKSATIEPKEVKP-ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
Query: 453 PVIK 456
P +K
Sbjct: 447 PQLK 450
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 642 bits (1656), Expect = 0.0
Identities = 319/424 (75%), Positives = 358/424 (84%), Gaps = 7/424 (1%)
Query: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96
S++DE DN T+FTRILD LLDGYDNRLRPGLGER+T+V+TDI+VTSFGPVSD +MEYTI
Sbjct: 30 SLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTI 89
Query: 97 DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156
DVFFRQSWKDERL+FKGPM L LNNL+ASKIWTPDTFFHNGKKS+AHNMT PNKLLR+
Sbjct: 90 DVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT 149
Query: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216
+DGTLLYTMRLT+ AECPM LEDFPMDAHACPLKFGSYAY +EVVY WT +SVVVA
Sbjct: 150 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVA 209
Query: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276
EDGSRLNQY L+GQTV + + +STGEY +MT HFHLKRKIGYFVIQTYLPCIMTVILSQ
Sbjct: 210 EDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQ 269
Query: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336
VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI
Sbjct: 270 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 329
Query: 337 EFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQ 392
EFATVNYFTKRG+AWDGK + K KK ++ ++ K+ N + S+ PN+ P
Sbjct: 330 EFATVNYFTKRGYAWDGKSVV-PEKPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLA 387
Query: 393 TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452
T A ++ VKP E K E KKT+NS+SKID++SRI FP+LFG FNLVYWATYLNRE
Sbjct: 388 TIAKSATIEPKEVKP-ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
Query: 453 PVIK 456
P +K
Sbjct: 447 PQLK 450
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 509 bits (1310), Expect = e-144
Identities = 255/416 (61%), Positives = 305/416 (73%), Gaps = 17/416 (4%)
Query: 50 TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERL 109
+RILD LL+GYDNRLRPG G +T+V+TDIYVTSFGPVSD EMEYT+DVFFRQ+W DERL
Sbjct: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
Query: 110 RFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTI 169
+F GP + L LNNL+ SKIWTPDTFF NGKKSIAHNMTTPNKL R+ +GT+LYTMRLTI
Sbjct: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
Query: 170 SAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMG 229
+A+CPM+L +FPMD HACPLKFGSYAYP SE++Y W G SV V E+ S L QY L+G
Sbjct: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
Query: 230 QTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 289
QTV +E I ++TGEY IMT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
Query: 290 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGW 349
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTN--- 329
Query: 350 AWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPP------------NIPKEQTPAGT 397
+KA A+ V ++K+T + HP ++P +
Sbjct: 330 -LQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEAN 388
Query: 398 SNTTSVSVKPSEEKTSES-KKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452
T + S T + SKID+ SRI+FPV F FNLVYW YL+++
Sbjct: 389 KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 479 bits (1234), Expect = e-135
Identities = 223/297 (75%), Positives = 262/297 (88%)
Query: 49 FTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDER 108
FTRILD LLDGYDNRLRPG G +T+V+TDIYVTSFGPVSD EMEYT+DVFFRQ+W D+R
Sbjct: 48 FTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKR 107
Query: 109 LRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLT 168
L++ GP++ L LNN++ +K+WTPDTFF NGKKS++HNMT PNKL R+ +GT+LYTMRLT
Sbjct: 108 LKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLT 167
Query: 169 ISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLM 228
ISAECPM+L DFPMD HACPLKFGSYAYP SE++Y WT G KSV V ++ S L QY L+
Sbjct: 168 ISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLI 227
Query: 229 GQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
GQTV +E I + TGEY +MT +FHL+RK+GYF+IQTY+PCIMTVILSQVSFW+N+ESVPA
Sbjct: 228 GQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPA 287
Query: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT 345
RTVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 288 RTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT 344
Score = 50.4 bits (119), Expect = 3e-06
Identities = 26/61 (42%), Positives = 35/61 (57%), Gaps = 5/61 (8%)
Query: 396 GTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVI 455
G + S + PS S S SKIDK +RI+FPV FG FN+VYW YL+++ +
Sbjct: 494 GATGKLSATPPPSAPPPSGS-----GTSKIDKYARILFPVTFGAFNMVYWVVYLSKDTME 548
Query: 456 K 456
K
Sbjct: 549 K 549
>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
[Homo sapiens]
Length = 465
Score = 375 bits (962), Expect = e-104
Identities = 196/404 (48%), Positives = 259/404 (64%), Gaps = 9/404 (2%)
Query: 50 TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERL 109
T+IL+ LL GYDN+LRP +G R T + TD+YV S GPV MEYTID+ F Q+W D RL
Sbjct: 65 TQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRL 124
Query: 110 RFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTI 169
+F M+ L LN+ + KIW PDTFF N +KS AH +TTPN+LLR+ +DG +LYT+RLTI
Sbjct: 125 KFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTI 184
Query: 170 SAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMG 229
+AEC +QL +FPMD H+CPL+F SY YP +E+ Y W S + V RL Q+ +G
Sbjct: 185 NAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVE--VADPKYWRLYQFAFVG 242
Query: 230 QTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 289
TE T +G+Y IMT F L R++GYF IQTY+PCI+TV+LS VSFW+N+++VPAR
Sbjct: 243 LRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPAR 302
Query: 290 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGW 349
T G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVF+AL+E+ T++YFT
Sbjct: 303 TSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN-- 360
Query: 350 AWDGKKALEAAKIKKKREVI--LNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKP 407
GK A + K+K K + L+ + +S P + S
Sbjct: 361 -QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCF 419
Query: 408 SEEKTSESK--KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYL 449
+ +T + + + I+KID SRI FP F FNLVYW YL
Sbjct: 420 EDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYL 463
>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
precursor [Homo sapiens]
Length = 467
Score = 365 bits (937), Expect = e-101
Identities = 189/408 (46%), Positives = 263/408 (64%), Gaps = 17/408 (4%)
Query: 50 TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERL 109
T IL+ LL+GYDN+LRP +G + T + TD+YV S GPV+ MEYTID+FF Q+W D RL
Sbjct: 67 TVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRL 126
Query: 110 RFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTI 169
+F ++ L LN+ + KIW PDTFF N KK+ AH +TTPN++LR+ +DG +LYT+RLTI
Sbjct: 127 KFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTI 186
Query: 170 SAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGS-RLNQYHLM 228
AEC +QL +FPMD H+CPL+F SY YP E+VY W SV V + S RL Q+ +
Sbjct: 187 DAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFV 243
Query: 229 GQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
G TE + T++G+Y +M+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPA
Sbjct: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPA 303
Query: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 348
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF
Sbjct: 304 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV--- 360
Query: 349 WAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAG-----TSNTTSV 403
+K + KKK T +M++ ++ + G + S
Sbjct: 361 ---SNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417
Query: 404 SVKPSEEKTSESK--KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYL 449
+ +T + + + I+K+D +RI FP F FNLVYW +YL
Sbjct: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
precursor [Homo sapiens]
Length = 475
Score = 365 bits (937), Expect = e-101
Identities = 192/416 (46%), Positives = 268/416 (64%), Gaps = 25/416 (6%)
Query: 50 TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERL 109
T IL+ LL+GYDN+LRP +G + T + TD+YV S GPV+ MEYTID+FF Q+W D RL
Sbjct: 67 TVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRL 126
Query: 110 RFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTI 169
+F ++ L LN+ + KIW PDTFF N KK+ AH +TTPN++LR+ +DG +LYT+RLTI
Sbjct: 127 KFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTI 186
Query: 170 SAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGS-RLNQYHLM 228
AEC +QL +FPMD H+CPL+F SY YP E+VY W SV V + S RL Q+ +
Sbjct: 187 DAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFV 243
Query: 229 GQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
G TE + T++G+Y +M+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPA
Sbjct: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPA 303
Query: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 348
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF
Sbjct: 304 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV--- 360
Query: 349 WAWDGKKALEAAKIKKKREVILNKSTNAFT--------TGKMSHPPNIPKEQTPAG---- 396
+K + KKK ++ S A T T +M++ ++ + G
Sbjct: 361 ---SNRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECL 417
Query: 397 -TSNTTSVSVKPSEEKTSESK--KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYL 449
+ S + +T + + + I+K+D +RI FP F FNLVYW +YL
Sbjct: 418 DGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 473
>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
Length = 467
Score = 349 bits (895), Expect = 3e-96
Identities = 192/423 (45%), Positives = 255/423 (60%), Gaps = 22/423 (5%)
Query: 47 TIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKD 106
T T IL+ LL YD +LRP +G + T + DIYV S GPVS MEY ID+FF Q+W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 107 ERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMR 166
RLRF M+ L LN+ + IW PDT F N K + AH +TTPN+LLR+ +DG +LYT+R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 167 LTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYH 226
LTI+AEC +QL +FPMD H+CPL F SY YP E++Y W S ++ + RL Q+
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEA--ADQKSWRLYQFD 222
Query: 227 LMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 286
MG TE ++TS G+Y +MT +F L R++GYF IQTY+PCI+TV+LS VSFW+ +++
Sbjct: 223 FMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDAT 282
Query: 287 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 346
PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+NY++
Sbjct: 283 PARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSS 342
Query: 347 RGWAWDGKKALEAAKIKKKR---EVILNKSTNAFTTGKMSHPP-------NIPKEQTPAG 396
KK R E I ++ + ++ M PP N Q
Sbjct: 343 CRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFED 402
Query: 397 TSNTTSVSVKPS-------EEKTSES---KKTYNSISKIDKMSRIVFPVLFGTFNLVYWA 446
T + K EE S S + + I ++D SR+ FP F FNLVYW
Sbjct: 403 TCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWV 462
Query: 447 TYL 449
YL
Sbjct: 463 GYL 465
>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
precursor [Homo sapiens]
Length = 515
Score = 344 bits (882), Expect = 1e-94
Identities = 191/456 (41%), Positives = 269/456 (58%), Gaps = 65/456 (14%)
Query: 50 TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERL 109
T IL+ LL+GYDN+LRP +G + T + TD+YV S GPV+ MEYTID+FF Q+W D RL
Sbjct: 67 TVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRL 126
Query: 110 RFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTI 169
+F ++ L LN+ + KIW PDTFF N KK+ AH +TTPN++LR+ +DG +LYT+RLTI
Sbjct: 127 KFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTI 186
Query: 170 SAECPMQLEDFPMDAHACPLKFGSYA---------------------------------- 195
AEC +QL +FPMD H+CPL+F S++
Sbjct: 187 DAECQLQLHNFPMDEHSCPLEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPPTLASRV 246
Query: 196 ------YPNSEVVYVWTNGSTKSVVVAEDGS-RLNQYHLMGQTVGTENISTSTGEYTIMT 248
YP E+VY W SV V + S RL Q+ +G TE + T++G+Y +M+
Sbjct: 247 AGISDGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMS 303
Query: 249 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 308
+F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTVLTMTTLS AR
Sbjct: 304 VYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIAR 363
Query: 309 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREV 368
SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF +K + KKK +
Sbjct: 364 KSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV------SNRKPSKDKDKKKKNPL 417
Query: 369 ILNKSTNAFT--------TGKMSHPPNIPKEQTPAG-----TSNTTSVSVKPSEEKTSES 415
+ S A T T +M++ ++ + G + S + +T
Sbjct: 418 LRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAW 477
Query: 416 K--KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYL 449
+ + + I+K+D +RI FP F FNLVYW +YL
Sbjct: 478 RHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 513
>gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon
precursor [Homo sapiens]
Length = 506
Score = 304 bits (779), Expect = 1e-82
Identities = 167/462 (36%), Positives = 255/462 (55%), Gaps = 56/462 (12%)
Query: 35 TSSVKDETNDNITIF---TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTE 91
T S + ET + +RIL+ +L YD++LRPG+GE+ T V +I V S GP+S +
Sbjct: 54 TKSTETETGSRVGKLPEASRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILD 113
Query: 92 MEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNK 151
MEYTID+ F Q+W DERL + + L LN + S++W PDTFF N K++ H +T PN+
Sbjct: 114 MEYTIDIIFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQ 173
Query: 152 LLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTK 211
++R+ DG +LYT+R+TI A C + + FPMD+H+CPL F S++YP +E++Y W N K
Sbjct: 174 MVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWEN--FK 231
Query: 212 SVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMT 271
+ ++ +L Q+ G + TE I+T G++ +MT F++ R+ GY Q Y+P +T
Sbjct: 232 LEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVT 291
Query: 272 VILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFV 331
+LS VSFW+ ES PART G+T+VLTMTTL +R + P+V+Y TA+D++IA+C+ F
Sbjct: 292 TMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFC 351
Query: 332 FSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKM--------- 382
F AL+EFA +N+ ++ KA + K++ R +N +A T +
Sbjct: 352 FCALLEFAVLNFL-----IYNQTKAHASPKLRHPR---INSRAHARTRARSRACARQHQE 403
Query: 383 --------------SHPPNIPKEQTPAGTSNTTSVS--------------------VKPS 408
P+ +Q P+ S S V
Sbjct: 404 AFVCQIVTTEGSDGEERPSCSAQQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDC 463
Query: 409 EEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLN 450
E T + + + ++D SR+VFPV F FN++YW LN
Sbjct: 464 EGSTWQQGRLCIHVYRLDNYSRVVFPVTFFFFNVLYWLVCLN 505
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 280 bits (716), Expect = 2e-75
Identities = 167/481 (34%), Positives = 250/481 (51%), Gaps = 49/481 (10%)
Query: 11 MIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGE 70
M LL + + LS G SV D N++ +D LL GYD RLRP G
Sbjct: 1 MCSGLLELLLPIWLSWTLGTRGSEPRSVNDP--GNMSFVKETVDKLLKGYDIRLRPDFGG 58
Query: 71 RITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWT 130
V +I + S VS+ M+YT+ ++F+Q W+D+RL + G L L+N +A ++W
Sbjct: 59 PPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWV 118
Query: 131 PDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLK 190
PDT+F N KKS H +T N+++RL DGT+LY +R+T +A C M L +P+D C L+
Sbjct: 119 PDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLE 178
Query: 191 FGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAH 250
SY Y ++ + W G V + L Q+ ++ + + N+ +TG Y ++
Sbjct: 179 IESYGYTTDDIEFYWRGGD--KAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLS 236
Query: 251 FHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNS 310
F LKR IGYF++QTY+P I+ ILS VSFW+N ++ AR G+TTVLTMTT++ R +
Sbjct: 237 FRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRET 296
Query: 311 LPKVAYATAMDWFIAVCYAFVFSALIEFATVNY-FTKRGWAWDGKKALEAAKIKKKREVI 369
LPK+ Y A+D ++ C+ FVF AL+E+A VNY F RG K A + AK K R
Sbjct: 297 LPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKS 356
Query: 370 LNKSTNA-----FTTGKMSHPPNIPKEQTPAGTSNTTSVSVK-------------PSE-- 409
+ +A T+ ++ + N + G +T + ++ P E
Sbjct: 357 ESNRVDAHGNILLTSLEVHNEMN----EVSGGIGDTRNSAISFDNSGIQYRKQSMPREGH 412
Query: 410 -----EKTSESKKTY---------------NSISKIDKMSRIVFPVLFGTFNLVYWATYL 449
+++ KKT+ ++ ID+ SRIVFP F FNLVYW Y+
Sbjct: 413 GRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYV 472
Query: 450 N 450
N
Sbjct: 473 N 473
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 278 bits (711), Expect = 7e-75
Identities = 158/447 (35%), Positives = 239/447 (53%), Gaps = 47/447 (10%)
Query: 45 NITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSW 104
N++ +D LL GYD RLRP G V +I + S VS+ M+YT+ ++F+Q W
Sbjct: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92
Query: 105 KDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYT 164
+D+RL + G L L+N +A ++W PDT+F N KKS H +T N+++RL DGT+LY
Sbjct: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152
Query: 165 MRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQ 224
+R+T +A C M L +P+D C L+ SY Y ++ + W G V + L Q
Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD--KAVTGVERIELPQ 210
Query: 225 YHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 284
+ ++ + + N+ +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N +
Sbjct: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270
Query: 285 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 343
+ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY
Sbjct: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330
Query: 344 FTKRGWAWDGKKALEAAKIKKKREVILNKSTNA-----FTTGKMSHPPNIPKEQTPAGTS 398
F RG K A + AK K R + +A T+ ++ + N + G
Sbjct: 331 FFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMN----EVSGGIG 386
Query: 399 NTTSVSVK-------------PSE-------EKTSESKKTY---------------NSIS 423
+T + ++ P E +++ KKT+ ++
Sbjct: 387 DTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVN 446
Query: 424 KIDKMSRIVFPVLFGTFNLVYWATYLN 450
ID+ SRIVFP F FNLVYW Y+N
Sbjct: 447 AIDRWSRIVFPFTFSLFNLVYWLYYVN 473
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 275 bits (702), Expect = 8e-74
Identities = 153/398 (38%), Positives = 236/398 (59%), Gaps = 9/398 (2%)
Query: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
L G GYD R+RP V +I++ SFG V++T M+Y +++F RQ W D RL +
Sbjct: 51 LMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYS 110
Query: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
P L L+ + IW PD FF N K + H++TT NKLLR+ +G +LY++RLT++
Sbjct: 111 EYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTL 170
Query: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
CPM L++FPMD C ++ S+ Y +++++ W S V VAE G L Q+ L +
Sbjct: 171 SCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVAE-GLTLPQFILKEEK 227
Query: 232 -VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPART 290
+G +TG++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR
Sbjct: 228 ELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARV 287
Query: 291 VFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWA 350
G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ +++
Sbjct: 288 ALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKE 347
Query: 351 WDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEE 410
+ + K + K E + +S F+ M H + K+ T A + + +P ++
Sbjct: 348 F--LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQV-KDGT-AVKATPANPLPQPPKD 403
Query: 411 KTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
+ KK + +ID +SR FP+ F FN+ YW TY
Sbjct: 404 GDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 275 bits (702), Expect = 8e-74
Identities = 150/400 (37%), Positives = 233/400 (58%), Gaps = 17/400 (4%)
Query: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
L G GYD R+RP V +I++ SFG +++T M+Y +++F RQ W D RL +
Sbjct: 50 LMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYS 109
Query: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
P L L+ + IW PD FF N K + H +TT NKLLR+ +G +LY++RLT++
Sbjct: 110 EYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTL 169
Query: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
CPM L++FPMD C ++ S+ Y +++++ W + ++ V +G L Q+ L +
Sbjct: 170 SCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD---EAPVQVAEGLTLPQFLLKEEK 226
Query: 232 ---VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
T++ +T G++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PA
Sbjct: 227 DLRYCTKHYNT--GKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPA 284
Query: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 348
R G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 285 RVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ- 343
Query: 349 WAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPS 408
K+ L + +K ++ + +S +FT M TP G ++ V K
Sbjct: 344 ----HKELLRFRRKRKNKDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSP 399
Query: 409 EEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
+E K + KID +SR FP+ F FN+ YW Y
Sbjct: 400 DEM---RKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 275 bits (702), Expect = 8e-74
Identities = 153/398 (38%), Positives = 236/398 (59%), Gaps = 9/398 (2%)
Query: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
L G GYD R+RP V +I++ SFG V++T M+Y +++F RQ W D RL +
Sbjct: 51 LMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYS 110
Query: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
P L L+ + IW PD FF N K + H++TT NKLLR+ +G +LY++RLT++
Sbjct: 111 EYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTL 170
Query: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
CPM L++FPMD C ++ S+ Y +++++ W S V VAE G L Q+ L +
Sbjct: 171 SCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVAE-GLTLPQFILKEEK 227
Query: 232 -VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPART 290
+G +TG++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR
Sbjct: 228 ELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARV 287
Query: 291 VFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWA 350
G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ +++
Sbjct: 288 ALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKE 347
Query: 351 WDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEE 410
+ + K + K E + +S F+ M H + K+ T A + + +P ++
Sbjct: 348 F--LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQV-KDGT-AVKATPANPLPQPPKD 403
Query: 411 KTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
+ KK + +ID +SR FP+ F FN+ YW TY
Sbjct: 404 GDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 274 bits (701), Expect = 1e-73
Identities = 152/398 (38%), Positives = 236/398 (59%), Gaps = 9/398 (2%)
Query: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
L G GYD R+RP V +I++ SFG +++T M+Y +++F RQ W D RL +
Sbjct: 51 LMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYS 110
Query: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
P L L+ + IW PD FF N K + H++TT NKLLR+ +G +LY++RLT++
Sbjct: 111 EYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTL 170
Query: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
CPM L++FPMD C ++ S+ Y +++++ W S V VAE G L Q+ L +
Sbjct: 171 SCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVAE-GLTLPQFILKEEK 227
Query: 232 -VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPART 290
+G +TG++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR
Sbjct: 228 ELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARV 287
Query: 291 VFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWA 350
G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ +++
Sbjct: 288 ALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKE 347
Query: 351 WDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEE 410
+ + K + K E + +S F+ M H + K+ T A + + +P ++
Sbjct: 348 F--LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQV-KDGT-AVKATPANPLPQPPKD 403
Query: 411 KTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
+ KK + +ID +SR FP+ F FN+ YW TY
Sbjct: 404 GDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 273 bits (698), Expect = 2e-73
Identities = 150/444 (33%), Positives = 232/444 (52%), Gaps = 40/444 (9%)
Query: 45 NITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSW 104
N++ +D LL GYD RLRP G V I V S VS+ M+YT+ ++F+QSW
Sbjct: 33 NMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSW 92
Query: 105 KDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYT 164
KD+RL + G L L+N +A ++W PDT+F N KKS H +T N+++RL DGT+LY
Sbjct: 93 KDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152
Query: 165 MRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQ 224
+R+T +A C M L +P+D C L+ SY Y ++ + W G + V + L Q
Sbjct: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGG--EGAVTGVNKIELPQ 210
Query: 225 YHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 284
+ ++ + ++ + +TG Y ++ F LKR IGYF++QTY+P + ILS VSFW+N +
Sbjct: 211 FSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYD 270
Query: 285 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYF 344
+ AR G+TTVLTMTT+S R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY
Sbjct: 271 ASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYI 330
Query: 345 ------TKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTS 398
K+G + + A E K++ + + +T ++ + + + T
Sbjct: 331 FFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVSDP 390
Query: 399 NTTSVSVKPSE---EKTSESKKTY-----------------------------NSISKID 426
T S + K S++ Y ++ ID
Sbjct: 391 KATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVKIPDLTDVNSID 450
Query: 427 KMSRIVFPVLFGTFNLVYWATYLN 450
K SR+ FP+ F FN+VYW Y++
Sbjct: 451 KWSRMFFPITFSLFNVVYWLYYVH 474
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 272 bits (695), Expect = 5e-73
Identities = 154/413 (37%), Positives = 232/413 (56%), Gaps = 22/413 (5%)
Query: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
L G GYD R+RP V +I++ SFG +++T M+Y +++F RQ W D RL +
Sbjct: 45 LMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYN 104
Query: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
P L L+ + IW PD FF N K + H +TT NKLLR+ +G +LY++R+T++
Sbjct: 105 EYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTL 164
Query: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
CPM L++FPMD C ++ S+ Y +++++ W + V DG L Q+ L +
Sbjct: 165 ACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE---QGAVQVADGLTLPQFILKEEK 221
Query: 232 ---VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
T++ +T G++T + A FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ PA
Sbjct: 222 DLRYCTKHYNT--GKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPA 279
Query: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 348
R G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 280 RVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ- 338
Query: 349 WAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQ-----TPAGTSNTTSV 403
K L + K++ F P + + A SNTT+
Sbjct: 339 -----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNP 393
Query: 404 SVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY--LNREPV 454
PS+ K KIDK+SRI FP+ F FN+ YW Y + RE V
Sbjct: 394 PPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDV 446
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 271 bits (692), Expect = 1e-72
Identities = 160/453 (35%), Positives = 241/453 (53%), Gaps = 43/453 (9%)
Query: 37 SVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTI 96
SV D +N +++ +D LL GYD RLRP G V +I + S VS+ M+YT+
Sbjct: 26 SVNDPSN--MSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTL 83
Query: 97 DVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLE 156
++F+Q+W+D+RL + L L+N +A ++W PDT+F N KKS H +T N+++RL
Sbjct: 84 TMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 143
Query: 157 DDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVA 216
DGT+LY +R+T +A C M L +P+D C L+ SY Y ++ + W + V
Sbjct: 144 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDD--NAVTG 201
Query: 217 EDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ 276
L Q+ ++ + T+ + STG Y ++ F LKR IGYF++QTY+P I+ ILS
Sbjct: 202 VTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSW 261
Query: 277 VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALI 336
VSFW+N ++ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+
Sbjct: 262 VSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALL 321
Query: 337 EFATVNY-FTKRGWAWDGKKALEAAKI-KKKREVILNKS-------------TNAFTTGK 381
E+A VNY F RG K A +AA +K + +NK N T +
Sbjct: 322 EYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLSTLEIKNEMATSE 381
Query: 382 MSHPPNIPKEQTPAGTSNTTS-------------------VSVKPS--EEKTSESKKT-- 418
P+ A +++ V+ K S + S+ K T
Sbjct: 382 AVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIP 441
Query: 419 -YNSISKIDKMSRIVFPVLFGTFNLVYWATYLN 450
++ ID+ SRI FPV+F FN+VYW Y+N
Sbjct: 442 DLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 474
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 271 bits (692), Expect = 1e-72
Identities = 155/423 (36%), Positives = 235/423 (55%), Gaps = 34/423 (8%)
Query: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
L G GYD R+RP V +I++ SFG +++T M+Y +++F RQ W D RL +
Sbjct: 45 LMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYN 104
Query: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
P L L+ + IW PD FF N K + H +TT NKLLR+ +G +LY++R+T++
Sbjct: 105 EYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTL 164
Query: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
CPM L++FPMD C ++ S+ Y +++++ W + V DG L Q+ L +
Sbjct: 165 ACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE---QGAVQVADGLTLPQFILKEEK 221
Query: 232 ---VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
T++ +T G++T + A FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ PA
Sbjct: 222 DLRYCTKHYNT--GKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPA 279
Query: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 348
R G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 280 RVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS--- 336
Query: 349 WAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSH-----------PPNIPKEQ----T 393
++ E + ++KR + N F + P + +
Sbjct: 337 -----RQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVK 391
Query: 394 PAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY--LNR 451
A SNTT+ PS+ K KIDK+SRI FP+ F FN+ YW Y + R
Sbjct: 392 GANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRR 451
Query: 452 EPV 454
E V
Sbjct: 452 EDV 454
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 266 bits (681), Expect = 2e-71
Identities = 151/410 (36%), Positives = 233/410 (56%), Gaps = 22/410 (5%)
Query: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
L G GYD R+RP V +I++ SFG +++T M+Y +++F RQ W D RL +
Sbjct: 50 LMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYS 109
Query: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
P L L+ + IW PD FF N K + H +TT NKLLR+ +G +LY++RLT++
Sbjct: 110 EYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTL 169
Query: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
CPM L++FPMD C ++ S+ Y +++++ W + ++ V +G L Q+ L +
Sbjct: 170 SCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD---EAPVQVAEGLTLPQFLLKEEK 226
Query: 232 ---VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
T++ +T G++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PA
Sbjct: 227 DLRYCTKHYNT--GKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPA 284
Query: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR- 347
R G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 285 RVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQH 344
Query: 348 ----GWAWDGKKALEAAKIKK-----KREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTS 398
+ K EA ++K + + +S +FT M TP G +
Sbjct: 345 KELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPN 404
Query: 399 NTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
+ V K +E K + KID +SR FP+ F FN+ YW Y
Sbjct: 405 HPVQVMPKSPDEM---RKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,037,535
Number of Sequences: 37866
Number of extensions: 647927
Number of successful extensions: 2363
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2186
Number of HSP's gapped (non-prelim): 95
length of query: 462
length of database: 18,247,518
effective HSP length: 106
effective length of query: 356
effective length of database: 14,233,722
effective search space: 5067205032
effective search space used: 5067205032
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.