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Search of human proteins with 4503835
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503835 frizzled 9 [Homo sapiens]
(591 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503835 frizzled 9 [Homo sapiens] 1229 0.0
gi|6005762 frizzled 10 [Homo sapiens] 775 0.0
gi|22547161 frizzled 4 [Homo sapiens] 552 e-157
gi|27894385 frizzled 5 precursor [Homo sapiens] 477 e-134
gi|4503827 frizzled 2 [Homo sapiens] 461 e-129
gi|4503833 frizzled 7 [Homo sapiens] 459 e-129
gi|13994190 frizzled 8 [Homo sapiens] 452 e-127
gi|4503825 frizzled 1 [Homo sapiens] 447 e-125
gi|8393378 frizzled 3 [Homo sapiens] 352 5e-97
gi|34734079 frizzled 6 [Homo sapiens] 350 2e-96
gi|5032099 smoothened [Homo sapiens] 154 3e-37
gi|170784838 secreted frizzled-related protein 4 [Homo sapiens] 120 3e-27
gi|188528609 secreted frizzled-related protein 5 [Homo sapiens] 107 4e-23
gi|48475052 secreted frizzled-related protein 2 precursor [Homo ... 107 4e-23
gi|38455388 frizzled-related protein [Homo sapiens] 107 4e-23
gi|56117838 secreted frizzled-related protein 1 [Homo sapiens] 98 2e-20
gi|29244926 corin [Homo sapiens] 94 4e-19
gi|13899255 membrane frizzled-related protein [Homo sapiens] 75 2e-13
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 65 2e-10
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 64 4e-10
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 53 9e-07
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 40 0.005
gi|74271832 G protein-coupled receptor 155 isoform 9 [Homo sapiens] 39 0.013
gi|74271834 G protein-coupled receptor 155 isoform 10 [Homo sapi... 39 0.013
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens] 39 0.018
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens] 39 0.018
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens] 39 0.018
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens] 39 0.018
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 38 0.023
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho... 38 0.030
>gi|4503835 frizzled 9 [Homo sapiens]
Length = 591
Score = 1229 bits (3180), Expect = 0.0
Identities = 591/591 (100%), Positives = 591/591 (100%)
Query: 1 MAVAPLRGALLLWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNL 60
MAVAPLRGALLLWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNL
Sbjct: 1 MAVAPLRGALLLWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNL 60
Query: 61 LGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARL 120
LGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARL
Sbjct: 61 LGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARL 120
Query: 121 RCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPA 180
RCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPA
Sbjct: 121 RCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPA 180
Query: 181 RPPGDLGPGAGGSGTCENPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSA 240
RPPGDLGPGAGGSGTCENPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSA
Sbjct: 181 RPPGDLGPGAGGSGTCENPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSA 240
Query: 241 LCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGA 300
LCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGA
Sbjct: 241 LCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGA 300
Query: 301 LYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHM 360
LYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHM
Sbjct: 301 LYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHM 360
Query: 361 AAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTG 420
AAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTG
Sbjct: 361 AAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTG 420
Query: 421 FVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRA 480
FVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRA
Sbjct: 421 FVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRA 480
Query: 481 TEQPCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSL 540
TEQPCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSL
Sbjct: 481 TEQPCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSL 540
Query: 541 CYRKIAAGRARAKACRAPGSYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL 591
CYRKIAAGRARAKACRAPGSYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL
Sbjct: 541 CYRKIAAGRARAKACRAPGSYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL 591
>gi|6005762 frizzled 10 [Homo sapiens]
Length = 581
Score = 775 bits (2001), Expect = 0.0
Identities = 370/564 (65%), Positives = 445/564 (78%), Gaps = 18/564 (3%)
Query: 12 LWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAA 71
LW +L G+ I D ER G CQ +EIPMC+ IGYN+TRMPNL+GH +Q EAA
Sbjct: 8 LWLVLQVMGSCAAISSMDMERP-GDGKCQPIEIPMCKDIGYNMTRMPNLMGHENQREAAI 66
Query: 72 ELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNF 131
+L EFAPLV+YGCH HLRFFLCSLYAPMCT+QVSTPIPACR MCEQARL+C+PIMEQFNF
Sbjct: 67 QLHEFAPLVEYGCHGHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSPIMEQFNF 126
Query: 132 GWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPARPPG------- 184
WPDSLDC +LP +NDP+ LCMEAP N G EP +G G+ P RP RP
Sbjct: 127 KWPDSLDCRKLPNKNDPNYLCMEAPNN---GSDEPTRGSGLFPPLFRPQRPHSAQEHPLK 183
Query: 185 DLGPGAGGSGTCENPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFF 244
D GPG GG C+NP KF +VEKS SCAP C PGV+V+WSR DK FA+VW+A+W+ LCFF
Sbjct: 184 DGGPGRGG---CDNPGKFHHVEKSASCAPLCTPGVDVYWSREDKRFAVVWLAIWAVLCFF 240
Query: 245 STAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVI 304
S+AFTVLTFL++P RF+YPERPIIFLSMCY VYS+ +LIR AGA+S+ACD+++G LYVI
Sbjct: 241 SSAFTVLTFLIDPARFRYPERPIIFLSMCYCVYSVGYLIRLFAGAESIACDRDSGQLYVI 300
Query: 305 QEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWG 364
QEGLE+TGCTLVFL+LYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEA+ SYFH+AAW
Sbjct: 301 QEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWA 360
Query: 365 LPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVAL 424
+PA+KTI+IL +R+VAGDELTG+CYV S D ALTGFVL+PL+ YLV+G+SF+L+GFVAL
Sbjct: 361 IPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLIPLACYLVIGTSFILSGFVAL 420
Query: 425 FHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQP 484
FHIR++MKTGG NT+KLEKLMV+IG+FS+LYTVPATCVI CY YERLNMD+W++ A +
Sbjct: 421 FHIRRVMKTGGENTDKLEKLMVRIGLFSVLYTVPATCVIACYFYERLNMDYWKILAAQHK 480
Query: 485 CAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYRK 544
C DC L S+P V +FM+KIFM LVVGITSG+W+W+SKT Q+WQ +C R+
Sbjct: 481 C-KMNNQTKTLDC-LMAASIPAVEIFMVKIFMLLVVGITSGMWIWTSKTLQSWQQVCSRR 538
Query: 545 I--AAGRARAKACRAPGSYGRGTH 566
+ + R A + G Y + H
Sbjct: 539 LKKKSRRKPASVITSGGIYKKAQH 562
>gi|22547161 frizzled 4 [Homo sapiens]
Length = 537
Score = 552 bits (1423), Expect = e-157
Identities = 275/542 (50%), Positives = 362/542 (66%), Gaps = 47/542 (8%)
Query: 11 LLWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAA 70
LL QLL G A G D E R C + I MC+ +GYN+T+MPNL+GH Q +A
Sbjct: 23 LLLQLLLLLGPARGFG--DEEERR----CDPIRISMCQNLGYNVTKMPNLVGHELQTDAE 76
Query: 71 AELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFN 130
+L F PL+QYGC S L+FFLCS+Y PMCT++++ PI C MC + RC P++++F
Sbjct: 77 LQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFG 136
Query: 131 FGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPARPPGDLGPGA 190
F WP+SL+C++ P +ND + +CME P G E P P + P G
Sbjct: 137 FAWPESLNCSKFPPQNDHNHMCMEGP-----GDEE----------VPLPHKTPIQPGEEC 181
Query: 191 GGSGTCENPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTV 250
GT N +++ +V++S +C +CG ++ SR K+F +WMAVW++LCF STAFTV
Sbjct: 182 HSVGT--NSDQYIWVKRSLNCVLKCGYDAGLY-SRSAKEFTDIWMAVWASLCFISTAFTV 238
Query: 251 LTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACD-QEAGALYVIQEGLE 309
LTFL++ RF YPERPIIFLSMCYN+YS+A+++R G + ++CD +EA +IQEGL+
Sbjct: 239 LTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLK 298
Query: 310 NTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALK 369
NTGC ++FLL+Y+FGMASS+WWV+LTLTWFLAAG KWGHEAIE H SYFH+AAW +PA+K
Sbjct: 299 NTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVK 358
Query: 370 TIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVALFHIRK 429
TIVIL +R V DELTGLCYV + + ALTGFV+ PL YLV+G+ F+ G VALF IR
Sbjct: 359 TIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIRS 418
Query: 430 IMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCAAAA 489
++ GT T+KLE+LMVKIGVFS+LYTVPATCVI CY YE N +R A +
Sbjct: 419 NLQKDGTKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISNWALFRYSADDS------ 472
Query: 490 GPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYRKIAAGR 549
+AV MLKIFMSL+VGITSG+W+WS+KT TWQ R + +G+
Sbjct: 473 ----------------NMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGK 516
Query: 550 AR 551
+
Sbjct: 517 VK 518
>gi|27894385 frizzled 5 precursor [Homo sapiens]
Length = 585
Score = 477 bits (1228), Expect = e-134
Identities = 261/573 (45%), Positives = 338/573 (58%), Gaps = 52/573 (9%)
Query: 10 LLLWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEA 69
LLL QL+ AA + A CQ + +PMCRGIGYNLT MPN H +Q EA
Sbjct: 15 LLLAQLVGRAAAASK-----------APVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEA 63
Query: 70 AAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQF 129
E+ +F PLV+ C LRFFLCS+Y P+C P+P CR +CE+A+ C+P+M Q+
Sbjct: 64 GLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQY 123
Query: 130 NFGWPDSLDCARLPTRN-DPHALCMEAPEN-ATAGPAEPHKGLGMLPVAPRPARPPGDLG 187
F WP+ + C RLP D LCM+ + AT P P P P PPG
Sbjct: 124 GFAWPERMSCDRLPVLGRDAEVLCMDYNRSEATTAPPRP------FPAKPTLPGPPGAPA 177
Query: 188 PG----AGGSGTCENPEKFQYVEKSR---------SCAPRCG-PGVEVFWSRRDKDFALV 233
G AGG C+ E F + K P C P + +S ++ FA
Sbjct: 178 SGGECPAGGPFVCKCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSADERTFATF 237
Query: 234 WMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVA 293
W+ +WS LCF ST+ TV TFL++ RF+YPERPIIFLS CY SL FL+R V G SVA
Sbjct: 238 WIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVA 297
Query: 294 CDQEAGALYVIQEGLENTG---CTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEA 350
C +E ++ E TG CT+VFLL+Y+FGMASS+WWV+L+LTWFLAAG KWG+EA
Sbjct: 298 CSREHNHIHY-----ETTGPALCTIVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEA 352
Query: 351 IEAHGSYFHMAAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYL 410
I + YFH+AAW +P++K+I L L V GD + G+CYV + + +L GFVL PL YL
Sbjct: 353 IAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYL 412
Query: 411 VLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYER 470
++G+ FLL GFV+LF IR ++K GGT T+KLEKLM++IG+F++LYTVPA+ V+ CY+YE+
Sbjct: 413 LVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQ 472
Query: 471 LNMDFWRLRATEQPCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWS 530
+ W T CA PG D P P V MLK FM LVVGITSGVW+WS
Sbjct: 473 HYRESWEAALT---CAC---PG--HDTGQPRAK-PEYWVLMLKYFMCLVVGITSGVWIWS 523
Query: 531 SKTFQTWQSLCYRKIAAGRARAKA--CRAPGSY 561
KT ++W+ R R K+ A G Y
Sbjct: 524 GKTVESWRRFTSRCCCRPRRGHKSGGAMAAGDY 556
>gi|4503827 frizzled 2 [Homo sapiens]
Length = 565
Score = 461 bits (1185), Expect = e-129
Identities = 256/562 (45%), Positives = 333/562 (59%), Gaps = 46/562 (8%)
Query: 10 LLLWQLLAAGGAALEIGRFDPERGRGAAP---CQAVEIPMCRGIGYNLTRMPNLLGHTSQ 66
LL LL A G A +F E+G CQ + IP+C I YN T MPNLLGHT+Q
Sbjct: 11 LLPLLLLPAAGPA----QFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQ 66
Query: 67 GEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIM 126
+A E+ +F PLV+ C LRFFLCS+YAP+CT + IP CR +CE+AR C +M
Sbjct: 67 EDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCT-VLEQAIPPCRSICERARQGCEALM 125
Query: 127 EQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPARPPG-- 184
+F F WP+ L C P R+ +C+ + PA +L AP P PG
Sbjct: 126 NKFGFQWPERLRCEHFP-RHGAEQICVGQNHSEDGAPA-------LLTTAPPPGLQPGAG 177
Query: 185 --DLGPGAGGS----GTCENPEKFQYVEK-----------SRSCAPRCGPGV---EVFWS 224
GPG GG+ T E+P V K R CA C P +F+S
Sbjct: 178 GTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFS 237
Query: 225 RRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIR 284
+ + FA +W+ WS LC ST FTV T+L++ RF+YPERPIIFLS CY + S+A++
Sbjct: 238 QEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAG 297
Query: 285 AVAGAQSVACDQ---EAGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLA 341
V + V C++ E G V+Q G + GCT++F++LY+F MASS+WWV+L+LTWFLA
Sbjct: 298 FVL-QERVVCNERFSEDGYRTVVQ-GTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLA 355
Query: 342 AGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGF 401
AG KWGHEAIEA+ YFH+AAW +PA+KTI IL + ++ GD L+G+C+V L GF
Sbjct: 356 AGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGF 415
Query: 402 VLVPLSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATC 461
VL PL YL +G+SFLL GFV+LF IR IMK GT TEKLE+LMV+IGVFS+LYTVPAT
Sbjct: 416 VLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATI 475
Query: 462 VIVCYVYERLNMDFWRLRATEQPCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVG 521
VI CY YE+ + W Q C + A P P V+M+K M+L+VG
Sbjct: 476 VIACYFYEQAFREHWERSWVSQHCKSLAIP---CPAHYTPRMSPDFTVYMIKYLMTLIVG 532
Query: 522 ITSGVWVWSSKTFQTWQSLCYR 543
ITSG W+WS KT +W+ R
Sbjct: 533 ITSGFWIWSGKTLHSWRKFYTR 554
>gi|4503833 frizzled 7 [Homo sapiens]
Length = 574
Score = 459 bits (1181), Expect = e-129
Identities = 254/570 (44%), Positives = 341/570 (59%), Gaps = 40/570 (7%)
Query: 2 AVAPLRGALLLWQLLAAGGAALEIGRFDPERGRGAAP------CQAVEIPMCRGIGYNLT 55
A APL L +LA GA P G CQ + IP+C I YN T
Sbjct: 6 AAAPLSSLGLCALVLALLGALSAGAGAQPYHGEKGISVPDHGFCQPISIPLCTDIAYNQT 65
Query: 56 RMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMC 115
+PNLLGHT+Q +A E+ +F PLV+ C LRFFLCS+YAP+CT + IP CR +C
Sbjct: 66 ILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCT-VLDQAIPPCRSLC 124
Query: 116 EQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPV 175
E+AR C +M +F F WP+ L C P +C+ +N + G P G P
Sbjct: 125 ERARQGCEALMNKFGFQWPERLRCENFPVHGAGE-ICVG--QNTSDGSGGPGGGPTAYPT 181
Query: 176 APR-PARPPGDLGPGAG-GSG------TCENPEK------FQYVEKSRSCAPRCGPGVE- 220
AP P P L PGA G G +C K ++++ + R C C PG
Sbjct: 182 APYLPDLPFTALPPGASDGRGRPAFPFSCPRQLKVPPYLGYRFLGE-RDCGAPCEPGRAN 240
Query: 221 --VFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYS 278
+++ ++ FA +W+ VWS LC ST FTVLT+L++ RF YPERPIIFLS CY + +
Sbjct: 241 GLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVA 300
Query: 279 LAFLIRAVAGAQSVACDQEAGALY-VIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLT 337
+A + + ++V ++ + Y + +G + GCT++F++LY+FGMASS+WWV+L+LT
Sbjct: 301 VAHVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLT 360
Query: 338 WFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAA 397
WFLAAG KWGHEAIEA+ YFH+AAW +PA+KTI IL + +V GD L+G+CYV + A
Sbjct: 361 WFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDA 420
Query: 398 LTGFVLVPLSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTV 457
L GFVL PL YL +G+SFLL GFV+LF IR IMK GT TEKLEKLMV+IGVFS+LYTV
Sbjct: 421 LRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTV 480
Query: 458 PATCVIVCYVYERLNMDFWRLRATEQPCAAAAGPGGRRDCSLPGGSVPTVA----VFMLK 513
PAT V+ CY YE+ + W Q C + A P P G P ++ VFM+K
Sbjct: 481 PATIVLACYFYEQAFREHWERTWLLQTCKSYAVP-------CPPGHFPPMSPDFTVFMIK 533
Query: 514 IFMSLVVGITSGVWVWSSKTFQTWQSLCYR 543
M+++VGIT+G W+WS KT Q+W+ +R
Sbjct: 534 YLMTMIVGITTGFWIWSGKTLQSWRRFYHR 563
>gi|13994190 frizzled 8 [Homo sapiens]
Length = 694
Score = 452 bits (1162), Expect = e-127
Identities = 263/639 (41%), Positives = 345/639 (53%), Gaps = 118/639 (18%)
Query: 31 ERGRGAAP-------CQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYG 83
+R GAA CQ + +P+C+GIGYN T MPN H +Q EA E+ +F PLV+
Sbjct: 20 QRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQ 79
Query: 84 CHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLP 143
C L+FFLCS+Y P+C + P+P CR +CE+A+ CAP+M Q+ F WPD + C RLP
Sbjct: 80 CSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLP 139
Query: 144 TRNDPHALCME--APENATAGPAEPHK--------------GLGMLPVAPRPAR------ 181
+ +P LCM+ + TA P+ P + G G P A P R
Sbjct: 140 EQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPGEQPPSGSGHGRPPGARPPHRGGGRGG 199
Query: 182 -------PP-------GDLGPGAGGSGTCE------------NPEKFQYVEKSRS----- 210
PP G P GG+ CE + E+ + ++
Sbjct: 200 GGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRVKTGQIAN 259
Query: 211 CAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFL 270
CA C F+S+ ++ F + W+ +WS LCF ST TV TFL++ RF+YPERPIIFL
Sbjct: 260 CALPCH---NPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERPIIFL 316
Query: 271 SMCYNVYSLAFLIRAVAGAQSVACD----------------------------------- 295
S CY S+ +L+R VAG + VAC
Sbjct: 317 SACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEY 376
Query: 296 QEAGAL--YVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEA 353
+E GA+ +V E CT+VFLL+Y+FGMASS+WWV+L+LTWFLAAG KWG+EAI
Sbjct: 377 EELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAG 436
Query: 354 HGSYFHMAAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLG 413
+ YFH+AAW +P++K+I +L L V GD + G+CYV + L GFVL PL YL +G
Sbjct: 437 YSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIG 496
Query: 414 SSFLLTGFVALFHIRKIMK--TGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERL 471
+ FLL GFV+LF IR ++K G T T KLEKLM+++G+F++LYTVPA V+ C YE+
Sbjct: 497 TMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQH 556
Query: 472 NMDFWRLRATEQ-PCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWS 530
N W AT PC RD P AVFMLK FM LVVGITSGVWVWS
Sbjct: 557 NRPRW--EATHNCPCL--------RDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWS 606
Query: 531 SKTFQTWQSLCYR-----KIAAGRARAKACRAPGSYGRG 564
KT ++W+SLC R K AA A A A G G G
Sbjct: 607 GKTLESWRSLCTRCCWASKGAAVGGGAGATAAGGGGGPG 645
>gi|4503825 frizzled 1 [Homo sapiens]
Length = 647
Score = 447 bits (1149), Expect = e-125
Identities = 244/534 (45%), Positives = 316/534 (59%), Gaps = 42/534 (7%)
Query: 39 CQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAP 98
CQ + IP+C I YN T MPNLLGHT+Q +A E+ +F PLV+ C + L+FFLCS+YAP
Sbjct: 116 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAP 175
Query: 99 MCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEA--- 155
+CT + +P CR +CE+AR C +M +F F WPD+L C + P LC+
Sbjct: 176 VCT-VLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGE-LCVGQNTS 233
Query: 156 ----------PENATAGPAEPHKGLGMLPVAPRPARPPGDLGPGAGGSGTCENPEKFQ-- 203
PE T+ P H G G PG G G +C K
Sbjct: 234 DKGTPTPSLLPEFWTSNPQ--HGGGG------HRGGFPGGAGASERGKFSCPRALKVPSY 285
Query: 204 ---YVEKSRSCAPRCGPGVE---VFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEP 257
+ + C C P +++ + F+ W+ +WS LC ST FTVLT+L++
Sbjct: 286 LNYHFLGEKDCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDM 345
Query: 258 HRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQ--EAGALYVIQEGLENTGCTL 315
RF YPERPIIFLS CY ++A++ + + V D+ E GA V Q G + GCT+
Sbjct: 346 RRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGARTVAQ-GTKKEGCTI 404
Query: 316 VFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILT 375
+F++LY+F MASS+WWV+L+LTWFLAAG KWGHEAIEA+ YFH+AAW +PA+KTI IL
Sbjct: 405 LFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILA 464
Query: 376 LRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVALFHIRKIMKTGG 435
L +V GD L+G+C+V + AL GFVL PL YL +G+SFLL GFV+LF IR IMK G
Sbjct: 465 LGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG 524
Query: 436 TNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCAAAAGP---- 491
T TEKLEKLMV+IGVFS+LYTVPAT VI CY YE+ D W Q C + A P
Sbjct: 525 TKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHL 584
Query: 492 --GGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYR 543
GG P P VFM+K M+L+VGITSG W+WS KT +W+ R
Sbjct: 585 QAGGGAPPHPP--MSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTR 636
>gi|8393378 frizzled 3 [Homo sapiens]
Length = 666
Score = 352 bits (903), Expect = 5e-97
Identities = 194/513 (37%), Positives = 280/513 (54%), Gaps = 31/513 (6%)
Query: 33 GRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFL 92
G C+ + + MC+ + YN T MPNLL H Q AA + F P+V C R FL
Sbjct: 22 GHSLFSCEPITLRMCQDLPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNLDCSRDFRPFL 81
Query: 93 CSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALC 152
C+LYAP+C + +P CR +C++A C+ +ME F WP+ ++C+R P ++P+
Sbjct: 82 CALYAPICMEYGRVTLP-CRRLCQRAYSECSKLMEMFGVPWPEDMECSRFPDCDEPYPRL 140
Query: 153 ME---APENATAGPAEPHKGLGMLPVAPRPARPPGDLGPGAGGSGTCENPEKFQYVEKSR 209
++ A E P + G PR + DLG F +V R
Sbjct: 141 VDLNLAGEPTEGAPVAVQRDYGFW--CPRELKIDPDLG------------YSFLHV---R 183
Query: 210 SCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIF 269
C+P C +++ R + FA ++ + S +C +T FT LTFL++ RF+YPERPIIF
Sbjct: 184 DCSPPCP---NMYFRREELSFARYFIGLISIICLSATLFTFLTFLIDVTRFRYPERPIIF 240
Query: 270 LSMCYNVYSLAFLIRAVAGAQSVACDQEAGALY---VIQEGLENTGCTLVFLLLYYFGMA 326
++CY + SL F I + VAC+ A Y + +G N CT++F++LY+F MA
Sbjct: 241 YAVCYMMVSLIFFIGFLL-EDRVACNASIPAQYKASTVTQGSHNKACTMLFMILYFFTMA 299
Query: 327 SSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTLRKVAGDELTG 386
S+WWV+LT+TWFLAA KWG EAIE FH +AWG+P TI++L + K+ GD ++G
Sbjct: 300 GSVWWVILTITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISG 359
Query: 387 LCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMV 446
+C+V D AL FVL PL Y+V+G S LL G ++L +R + N +KL K M+
Sbjct: 360 VCFVGLYDVDALRYFVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLEKENQDKLVKFMI 419
Query: 447 KIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCAAAAGPGGRRDCSLPGGSVPT 506
+IGVFSILY VP VI CY YE+ W ++ C P + + S P
Sbjct: 420 RIGVFSILYLVPLLVVIGCYFYEQAYRGIWETTWIQERCREYHIPCPYQVTQM---SRPD 476
Query: 507 VAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQS 539
+ +F++K M+L+VGI S WV S KT W S
Sbjct: 477 LILFLMKYLMALIVGIPSVFWVGSKKTCFEWAS 509
>gi|34734079 frizzled 6 [Homo sapiens]
Length = 706
Score = 350 bits (898), Expect = 2e-96
Identities = 193/525 (36%), Positives = 286/525 (54%), Gaps = 57/525 (10%)
Query: 32 RGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFF 91
RG C+ + +P C + YN+T PNL+GH Q AA E+ F PL C ++ F
Sbjct: 17 RGHSLFTCEPITVPRCMKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPLANLECSPNIETF 76
Query: 92 LCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARL-------PT 144
LC + P C +Q+ +P CR +CE+ C +++ F WP+ L+C RL P
Sbjct: 77 LCKAFVPTCIEQIHV-VPPCRKLCEKVYSDCKKLIDTFGIRWPEELECDRLQYCDETVPV 135
Query: 145 RNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPARPPGDLGPGAGGSGTCENPEKFQY 204
DPH + P+ T + + +G PR + G G KF
Sbjct: 136 TFDPHTEFL-GPQKKTE---QVQRDIGFW--CPRHLKTSGGQG------------YKFLG 177
Query: 205 VEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPE 264
+++ CAP C +++ + +FA ++ S C +T FT LTFL++ RF+YPE
Sbjct: 178 IDQ---CAPPCP---NMYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPE 231
Query: 265 RPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQ-----EAGALYVIQEGLENTGCTLVFLL 319
RPII+ S+CY++ SL + I + G S AC++ E G V+ G +N CT++F+L
Sbjct: 232 RPIIYYSVCYSIVSLMYFIGFLLG-DSTACNKADEKLELGDTVVL--GSQNKACTVLFML 288
Query: 320 LYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTLRKV 379
LY+F MA ++WWV+LT+TWFLAAG+KW EAIE +FH AWG P T+++L + KV
Sbjct: 289 LYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGTPGFLTVMLLAMNKV 348
Query: 380 AGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTE 439
GD ++G+C+V D A FVL+PL + +G S LL G ++L H+R++++ G N E
Sbjct: 349 EGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQE 408
Query: 440 KLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRL-------RATEQPCAAAAGPG 492
KL+K M++IGVFS LY VP ++ CYVYE++N W + R PC A
Sbjct: 409 KLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRITWEITWVSDHCRQYHIPCPYQAKAK 468
Query: 493 GRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTW 537
R P +A+FM+K M+L+VGI++ WV S KT W
Sbjct: 469 AR----------PELALFMIKYLMTLIVGISAVFWVGSKKTCTEW 503
>gi|5032099 smoothened [Homo sapiens]
Length = 787
Score = 154 bits (388), Expect = 3e-37
Identities = 132/525 (25%), Positives = 221/525 (42%), Gaps = 67/525 (12%)
Query: 36 AAPCQAVEIPMCRG--IGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYG-CHSHLRFFL 92
AAPC+ + +C G + Y T SQ EA +L ++ L C + ++ L
Sbjct: 67 AAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLL 126
Query: 93 CSLYAPMC-TDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHAL 151
C++Y P C D+V P R +C+ R CA + + GWPD L C
Sbjct: 127 CAVYMPKCENDRVELP---SRTLCQATRGPCAIVERER--GWPDFLRCT----------- 170
Query: 152 CMEAPENATAGPAEPHKGLGMLPVAPRPARPPGDLGPGAGGSGTCENP-----EKFQYVE 206
P+ G + + SG CE P + E
Sbjct: 171 ----PDRFPEGCTNEVQNIKF------------------NSSGQCEVPLVRTDNPKSWYE 208
Query: 207 KSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLE-PHRFQYPER 265
C +C +F +D ++A + A+ T FT+ TF+ + + +YP
Sbjct: 209 DVEGCGIQCQN--PLFTEAEHQDMHS-YIAAFGAVTGLCTLFTLATFVADWRNSNRYPAV 265
Query: 266 PIIFLSMCYNVYSLAFLIRAVAGAQ-SVACDQEAGALYVIQEGLENTGCTLVFLLLYYFG 324
+ +++ C+ V S+ +L + + GA+ + C + E C ++F+++YY
Sbjct: 266 ILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEPTSNETLSCVIIFVIVYYAL 325
Query: 325 MASSLWWVVLTLTW---FLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTLRKVAG 381
MA +W+VVLT W F A G + + + SYFH+ W LP + T+ IL + +V G
Sbjct: 326 MAGVVWFVVLTYAWHTSFKALGTTY--QPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDG 383
Query: 382 DELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTE-- 439
D ++G+C+V + GFVL P+ L++G FL+ G + LF I+ G +E
Sbjct: 384 DSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKS--NHPGLLSEKA 441
Query: 440 --KLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQP-CAAAAGPGGRRD 496
K+ + M+++G+F L C+ Y+ N W + C A G
Sbjct: 442 ASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPTK 501
Query: 497 CSLPGGSV---PTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQ 538
+P + P++ V + +F GI WVW+ T W+
Sbjct: 502 QPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWR 546
>gi|170784838 secreted frizzled-related protein 4 [Homo sapiens]
Length = 346
Score = 120 bits (302), Expect = 3e-27
Identities = 64/156 (41%), Positives = 91/156 (58%), Gaps = 20/156 (12%)
Query: 9 ALLLWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGE 68
AL LW LA G RG APC+AV IPMCR + +N+TRMPN L H++Q
Sbjct: 8 ALCLWLHLALG-----------VRG---APCEAVRIPMCRHMPWNITRMPNHLHHSTQEN 53
Query: 69 AAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCT-DQVSTPIPACRPMCEQARLRCAPIME 127
A + ++ LV C + LRFFLC++YAP+CT + + PI C+ +C++AR C P+M+
Sbjct: 54 AILAIEQYEELVDVNCSAVLRFFLCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMK 113
Query: 128 QFNFGWPDSLDCARLPTRN-----DPHALCMEAPEN 158
+N WP+SL C LP + P A+ + PE+
Sbjct: 114 MYNHSWPESLACDELPVYDRGVCISPEAIVTDLPED 149
>gi|188528609 secreted frizzled-related protein 5 [Homo sapiens]
Length = 317
Score = 107 bits (266), Expect = 4e-23
Identities = 52/124 (41%), Positives = 72/124 (58%), Gaps = 8/124 (6%)
Query: 29 DPERGRG-AAPCQAVEIP----MCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYG 83
+P GR + P Q ++IP +C +GY R+PNLL H S E + + + PL+
Sbjct: 40 EPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKR 99
Query: 84 CHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLP 143
CHS + FLCSL+AP+C D+ PI CR +CE R CAP+ME + F WP+ L C + P
Sbjct: 100 CHSDTQVFLCSLFAPVCLDR---PIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFP 156
Query: 144 TRND 147
ND
Sbjct: 157 LDND 160
>gi|48475052 secreted frizzled-related protein 2 precursor [Homo
sapiens]
Length = 295
Score = 107 bits (266), Expect = 4e-23
Identities = 46/104 (44%), Positives = 60/104 (57%)
Query: 44 IPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQ 103
+ +C GI Y R+PNLLGH + E + + PLV CH + FLCSL+AP+C D
Sbjct: 47 LQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDD 106
Query: 104 VSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRND 147
+ I C +C Q + RCAP+M F F WPD L+C R P ND
Sbjct: 107 LDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDND 150
>gi|38455388 frizzled-related protein [Homo sapiens]
Length = 325
Score = 107 bits (266), Expect = 4e-23
Identities = 57/152 (37%), Positives = 84/152 (55%), Gaps = 3/152 (1%)
Query: 15 LLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELA 74
LL AG AL G AA C+ V IP+C+ + +N+T+MPN L H++Q A +
Sbjct: 11 LLRAGLLALAALCLLRVPGARAAACEPVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIE 70
Query: 75 EFAPLVQYGCHSHLRFFLCSLYAPMCT-DQVSTPIPACRPMCEQARLRCAPIMEQFNFGW 133
+F L+ C L FFLC++YAP+CT D PI C+ +CE+AR C PI+ ++ W
Sbjct: 71 QFEGLLGTHCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPILIKYRHSW 130
Query: 134 PDSLDCARLPTRNDPHALCMEAPENATAGPAE 165
P++L C LP + +C+ TA A+
Sbjct: 131 PENLACEELPVYD--RGVCISPEAIVTADGAD 160
>gi|56117838 secreted frizzled-related protein 1 [Homo sapiens]
Length = 314
Score = 97.8 bits (242), Expect = 2e-20
Identities = 62/181 (34%), Positives = 85/181 (46%), Gaps = 28/181 (15%)
Query: 7 RGALLLWQLLAAGGAALEIGRFDP-------------ERGRG-AAPCQAVEIP----MCR 48
RGA L LLA G A L +G + GR P Q V+IP +C
Sbjct: 11 RGAAL-GVLLALGAALLAVGSASEYDYVSFQSDIGPYQSGRFYTKPPQCVDIPADLRLCH 69
Query: 49 GIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPI 108
+GY +PNLL H + E + + + PL+ CH+ + FLCSL+AP+C D+ PI
Sbjct: 70 NVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVCLDR---PI 126
Query: 109 PACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLP------TRNDPHALCMEAPENATAG 162
CR +CE R C P+M+ F F WP+ L C + P P+A P+ T
Sbjct: 127 YPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASKPQGTTVC 186
Query: 163 P 163
P
Sbjct: 187 P 187
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 94.0 bits (232), Expect = 4e-19
Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 7/144 (4%)
Query: 17 AAGGAALEIGRFDPERG-RGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAA--EL 73
+ GG++L DP + C+ + + +C + YN T PN GH +Q EA+ E
Sbjct: 436 SCGGSSL----CDPNNSLNNCSQCEPITLELCMNLPYNSTSYPNYFGHRTQKEASISWES 491
Query: 74 AEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGW 133
+ F LVQ C+ +L FF C++ P C IP CR +CE ++ RC ++ W
Sbjct: 492 SLFPALVQTNCYKYLMFFSCTILVPKCDVNTGEHIPPCRALCEHSKERCESVLGIVGLQW 551
Query: 134 PDSLDCARLPTRNDPHALCMEAPE 157
P+ DC++ P N + C+ E
Sbjct: 552 PEDTDCSQFPEENSDNQTCLMPDE 575
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 5/117 (4%)
Query: 34 RGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLC 93
R + C + C+ + Y+ T P LL E L F L + C+ H+ F C
Sbjct: 134 RNTSACMNITHSQCQMLPYHATLTP-LLSVVRNMEMEKFLKFFTYLHRLSCYQHIMLFGC 192
Query: 94 SLYAPMCT---DQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRND 147
+L P C D +P CR CE A+ C ++ N+ WPD L C++ + +
Sbjct: 193 TLAFPECIIDGDDSHGLLP-CRSFCEAAKEGCESVLGMVNYSWPDFLRCSQFRNQTE 248
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 75.1 bits (183), Expect = 2e-13
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Query: 39 CQAVEIPMCRGIGYNLTRMPNL-LGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYA 97
C+ V++ MC G+ YN T PN+ +G +Q E L+ + L C+ H R LC L
Sbjct: 466 CEPVQVEMCLGLSYNTTAFPNIWVGMITQEEVVEVLSGYKSLTSLPCYQHFRRLLCGLLV 525
Query: 98 PMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHA 150
P CT + + +P CR +C++A +C + WP +C RLP D A
Sbjct: 526 PRCT-PLGSVLPPCRSVCQEAEHQCQSGLALLGTPWP--FNCNRLPEAADLEA 575
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 65.1 bits (157), Expect = 2e-10
Identities = 43/118 (36%), Positives = 57/118 (48%), Gaps = 9/118 (7%)
Query: 36 AAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQG--EAAAE---LAEFAPLVQYGCHSHLRF 90
AA C +++ C YN T PNLL H S EA++E L+ L++ C+ LR
Sbjct: 29 AATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRL 88
Query: 91 FLCSLYAPMCTDQ-VSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRND 147
C++ AP C V P CR +CE R C P + + WP LDC R TR D
Sbjct: 89 LGCAVLAPRCEGGWVRRP---CRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTRED 143
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 63.9 bits (154), Expect = 4e-10
Identities = 42/118 (35%), Positives = 57/118 (48%), Gaps = 9/118 (7%)
Query: 36 AAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQG--EAAAE---LAEFAPLVQYGCHSHLRF 90
+A C +++ C YN T PNLL H S EA++E L+ L++ C+ LR
Sbjct: 40 SATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRL 99
Query: 91 FLCSLYAPMCTDQ-VSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRND 147
C++ AP C V P CR +CE R C P + + WP LDC R TR D
Sbjct: 100 LGCAVLAPRCEGGWVRRP---CRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTRED 154
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 52.8 bits (125), Expect = 9e-07
Identities = 35/123 (28%), Positives = 50/123 (40%), Gaps = 4/123 (3%)
Query: 29 DPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHL 88
DPE G +P+C +G + +PN L H S + A + L+Q CH L
Sbjct: 326 DPEAPAGRCLPLPPSLPVCGHLGISRFWLPNHLHHESGEQVRAGARAWGGLLQTHCHPFL 385
Query: 89 RFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDP 148
+F C L P C P C CE + C + G + CA LPT+ D
Sbjct: 386 AWFFCLLLVPPCGSVPPPAPPPCCQFCEALQDACWSRLG----GGRLPVACASLPTQEDG 441
Query: 149 HAL 151
+ +
Sbjct: 442 YCV 444
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 40.4 bits (93), Expect = 0.005
Identities = 41/156 (26%), Positives = 63/156 (40%), Gaps = 25/156 (16%)
Query: 249 TVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGL 308
T+L RF ER II L+ C ++ + LI G V+ +G+
Sbjct: 949 TLLAIYAAFWRFIKSERSIILLNFCLSILASNILILV-------------GQSRVLSKGV 995
Query: 309 ENTGCTLVFLLLYYFGMASSLWWVVLTLTW--FLAAGKKWGHEAIEAHGSYFHMAAWGLP 366
CT+ L++F ++S W VLT W +LA + + F WGLP
Sbjct: 996 ----CTMTAAFLHFFFLSSFCW--VLTEAWQSYLAVIGRMRTRLVRKR---FLCLGWGLP 1046
Query: 367 ALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFV 402
AL V + + G + C++ S + L FV
Sbjct: 1047 ALVVAVSVGFTRTKGYGTSSYCWL-SLEGGLLYAFV 1081
>gi|74271832 G protein-coupled receptor 155 isoform 9 [Homo sapiens]
Length = 870
Score = 38.9 bits (89), Expect = 0.013
Identities = 47/216 (21%), Positives = 93/216 (43%), Gaps = 30/216 (13%)
Query: 217 PGVEVFWSRRDKDFALVWMAVW-----SALCFFSTAFTVLTFLLEPHRFQYPERPIIF-- 269
PGV +F ++ + + ++ + SA + +A+ + ++P Y + + F
Sbjct: 327 PGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDPKPLAYAIQNVSFDI 386
Query: 270 --LSMCYNVYSLAFLIRA-------------VAGAQSVACDQEAGALYVIQEGLENTGCT 314
+S+ ++SLA L+ + + AQS+ C +V ++ G
Sbjct: 387 SIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEKNF--VGQI 444
Query: 315 LVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVIL 374
LVF+LLY ++ LW +L ++ FL + E ++ ++ WG+PAL V+L
Sbjct: 445 LVFVLLYSSLYSTYLWTGLLAISLFLLKKR----ERVQIPVGIIIISGWGIPALLVGVLL 500
Query: 375 TLRKVAGDELTGLCYVASTD--AAALTGFVLVPLSG 408
K GD + + A+T F + ++G
Sbjct: 501 ITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAG 536
>gi|74271834 G protein-coupled receptor 155 isoform 10 [Homo
sapiens]
Length = 870
Score = 38.9 bits (89), Expect = 0.013
Identities = 47/216 (21%), Positives = 93/216 (43%), Gaps = 30/216 (13%)
Query: 217 PGVEVFWSRRDKDFALVWMAVW-----SALCFFSTAFTVLTFLLEPHRFQYPERPIIF-- 269
PGV +F ++ + + ++ + SA + +A+ + ++P Y + + F
Sbjct: 327 PGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDPKPLAYAIQNVSFDI 386
Query: 270 --LSMCYNVYSLAFLIRA-------------VAGAQSVACDQEAGALYVIQEGLENTGCT 314
+S+ ++SLA L+ + + AQS+ C +V ++ G
Sbjct: 387 SIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEKNF--VGQI 444
Query: 315 LVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVIL 374
LVF+LLY ++ LW +L ++ FL + E ++ ++ WG+PAL V+L
Sbjct: 445 LVFVLLYSSLYSTYLWTGLLAISLFLLKKR----ERVQIPVGIIIISGWGIPALLVGVLL 500
Query: 375 TLRKVAGDELTGLCYVASTD--AAALTGFVLVPLSG 408
K GD + + A+T F + ++G
Sbjct: 501 ITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAG 536
>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
Length = 995
Score = 38.5 bits (88), Expect = 0.018
Identities = 54/229 (23%), Positives = 92/229 (40%), Gaps = 38/229 (16%)
Query: 242 CFFSTAF---TVLTFL-LEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQE 297
C S+ F T++T++ E R YP + +I L + +L FL+ +
Sbjct: 614 CGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWI---------- 663
Query: 298 AGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSY 357
ALY +Q GL C V + L+YF + S W + +LA K + + I +
Sbjct: 664 --ALYKMQ-GL----CISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVF-NTYIRKYILK 715
Query: 358 FHMAAWGLPALKTIVILTLR----------KVAGDELTGLCYVASTDAAALT--GFVLVP 405
F + WG+PA+ +ILT+ K C++ + +T G+ V
Sbjct: 716 FCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCV- 774
Query: 406 LSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSIL 454
+L S + V L I+K + G ++ L G+ +L
Sbjct: 775 ---IFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLL 820
>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
Length = 1003
Score = 38.5 bits (88), Expect = 0.018
Identities = 54/229 (23%), Positives = 92/229 (40%), Gaps = 38/229 (16%)
Query: 242 CFFSTAF---TVLTFL-LEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQE 297
C S+ F T++T++ E R YP + +I L + +L FL+ +
Sbjct: 622 CGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWI---------- 671
Query: 298 AGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSY 357
ALY +Q GL C V + L+YF + S W + +LA K + + I +
Sbjct: 672 --ALYKMQ-GL----CISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVF-NTYIRKYILK 723
Query: 358 FHMAAWGLPALKTIVILTLR----------KVAGDELTGLCYVASTDAAALT--GFVLVP 405
F + WG+PA+ +ILT+ K C++ + +T G+ V
Sbjct: 724 FCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCV- 782
Query: 406 LSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSIL 454
+L S + V L I+K + G ++ L G+ +L
Sbjct: 783 ---IFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLL 828
>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
Length = 1017
Score = 38.5 bits (88), Expect = 0.018
Identities = 54/229 (23%), Positives = 92/229 (40%), Gaps = 38/229 (16%)
Query: 242 CFFSTAF---TVLTFL-LEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQE 297
C S+ F T++T++ E R YP + +I L + +L FL+ +
Sbjct: 636 CGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWI---------- 685
Query: 298 AGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSY 357
ALY +Q GL C V + L+YF + S W + +LA K + + I +
Sbjct: 686 --ALYKMQ-GL----CISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVF-NTYIRKYILK 737
Query: 358 FHMAAWGLPALKTIVILTLR----------KVAGDELTGLCYVASTDAAALT--GFVLVP 405
F + WG+PA+ +ILT+ K C++ + +T G+ V
Sbjct: 738 FCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCV- 796
Query: 406 LSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSIL 454
+L S + V L I+K + G ++ L G+ +L
Sbjct: 797 ---IFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLL 842
>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
Length = 1014
Score = 38.5 bits (88), Expect = 0.018
Identities = 54/229 (23%), Positives = 92/229 (40%), Gaps = 38/229 (16%)
Query: 242 CFFSTAF---TVLTFL-LEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQE 297
C S+ F T++T++ E R YP + +I L + +L FL+ +
Sbjct: 633 CGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWI---------- 682
Query: 298 AGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSY 357
ALY +Q GL C V + L+YF + S W + +LA K + + I +
Sbjct: 683 --ALYKMQ-GL----CISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVF-NTYIRKYILK 734
Query: 358 FHMAAWGLPALKTIVILTLR----------KVAGDELTGLCYVASTDAAALT--GFVLVP 405
F + WG+PA+ +ILT+ K C++ + +T G+ V
Sbjct: 735 FCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCV- 793
Query: 406 LSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSIL 454
+L S + V L I+K + G ++ L G+ +L
Sbjct: 794 ---IFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLL 839
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
sapiens]
Length = 1584
Score = 38.1 bits (87), Expect = 0.023
Identities = 38/146 (26%), Positives = 56/146 (38%), Gaps = 25/146 (17%)
Query: 259 RFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFL 318
R+ ER +I ++ C ++ S LI L + CTLV
Sbjct: 974 RYIRSERSVILINFCLSIISSNALI-----------------LIGQTQTRNKVVCTLVAA 1016
Query: 319 LLYYFGMASSLWWVVLTLTW--FLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTL 376
L++F ++S W VLT W ++A GH F WGLPAL + +
Sbjct: 1017 FLHFFFLSSFCW--VLTEAWQSYMAVT---GHLRNRLIRKRFLCLGWGLPALVVAISVGF 1071
Query: 377 RKVAGDELTGLCYVASTDAAALTGFV 402
K G C++ S + L FV
Sbjct: 1072 TKAKGYSTMNYCWL-SLEGGLLYAFV 1096
>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
sapiens]
Length = 1221
Score = 37.7 bits (86), Expect = 0.030
Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 22/145 (15%)
Query: 246 TAFTVLTFL-LEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVI 304
+A T+LT++ E R YP + ++ LS +L FL+ + +V
Sbjct: 879 SAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNV------------ 926
Query: 305 QEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWG 364
+GL C V +LL++F +A+ W + + ++A K + + I + F + WG
Sbjct: 927 -DGL----CIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVF-NTYIRRYILKFCIIGWG 980
Query: 365 LPALKTIVILTLR---KVAGDELTG 386
LPAL V+L R +V G E G
Sbjct: 981 LPALVVSVVLASRNNNEVYGKESYG 1005
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.455
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,559,120
Number of Sequences: 37866
Number of extensions: 1308532
Number of successful extensions: 5689
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 5522
Number of HSP's gapped (non-prelim): 181
length of query: 591
length of database: 18,247,518
effective HSP length: 108
effective length of query: 483
effective length of database: 14,157,990
effective search space: 6838309170
effective search space used: 6838309170
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.