Search of human proteins with 4503635

Search of human proteins with 4503635

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503635 coagulation factor II preproprotein [Homo sapiens]
         (622 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503635 coagulation factor II preproprotein [Homo sapiens]        1308   0.0  
gi|4505881 plasminogen [Homo sapiens]                                 242   9e-64
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]               238   2e-62
gi|4506115 protein C [Homo sapiens]                                   179   7e-45
gi|4503625 coagulation factor X preproprotein [Homo sapiens]          174   3e-43
gi|4503649 coagulation factor IX preproprotein [Homo sapiens]         161   2e-39
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           157   2e-38
gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo s...   156   6e-38
gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Ho...   156   6e-38
gi|4504383 HGF activator preproprotein [Homo sapiens]                 156   6e-38
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]           153   4e-37
gi|11415040 matriptase [Homo sapiens]                                 151   2e-36
gi|4506153 prostasin preproprotein [Homo sapiens]                     149   6e-36
gi|10518503 coagulation factor VII isoform b precursor [Homo sap...   149   1e-35
gi|4503645 coagulation factor VII isoform a precursor [Homo sapi...   149   1e-35
gi|223942069 enterokinase precursor [Homo sapiens]                    148   1e-35
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             147   2e-35
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr...   147   3e-35
gi|13994276 marapsin [Homo sapiens]                                   147   3e-35
gi|110578663 hypothetical protein LOC203074 [Homo sapiens]            144   3e-34
gi|5803197 testisin isoform 1 [Homo sapiens]                          143   5e-34
gi|21614531 testisin isoform 2 [Homo sapiens]                         142   9e-34
gi|66347875 complement component 1, r subcomponent [Homo sapiens]     141   2e-33
gi|33695155 hepsin [Homo sapiens]                                     140   3e-33
gi|4504481 hepsin [Homo sapiens]                                      140   3e-33
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi...   140   5e-33
gi|187761337 transmembrane protease, serine 11B [Homo sapiens]        139   6e-33
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]           139   1e-32
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]           137   2e-32
gi|4503137 chymotrypsin-like [Homo sapiens]                           136   7e-32

>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
          Length = 622

 Score = 1308 bits (3385), Expect = 0.0
 Identities = 622/622 (100%), Positives = 622/622 (100%)

Query: 1   MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLEREC 60
           MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLEREC
Sbjct: 1   MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLEREC 60

Query: 61  VEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHV 120
           VEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHV
Sbjct: 61  VEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHV 120

Query: 121 NITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQE 180
           NITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQE
Sbjct: 121 NITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQE 180

Query: 181 CSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASA 240
           CSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASA
Sbjct: 181 CSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASA 240

Query: 241 QAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETG 300
           QAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETG
Sbjct: 241 QAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETG 300

Query: 301 DGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI 360
           DGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI
Sbjct: 301 DGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI 360

Query: 361 DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 420
           DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN
Sbjct: 361 DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 420

Query: 421 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 480
           DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP
Sbjct: 421 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 480

Query: 481 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 540
           VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST
Sbjct: 481 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 540

Query: 541 RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY 600
           RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY
Sbjct: 541 RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY 600

Query: 601 GFYTHVFRLKKWIQKVIDQFGE 622
           GFYTHVFRLKKWIQKVIDQFGE
Sbjct: 601 GFYTHVFRLKKWIQKVIDQFGE 622


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  242 bits (617), Expect = 9e-64
 Identities = 167/556 (30%), Positives = 246/556 (44%), Gaps = 100/556 (17%)

Query: 77  STATDVFW--AKYTACETARTPRDKLAAC-------LEGNCAEGLGTNYRGHVNITRSGI 127
           +T + V W   K  +C+++    ++LA         +  +C  G G +YRG  + T +G 
Sbjct: 337 TTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGK 396

Query: 128 ECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCG 187
           +CQ W S  PH+ +     +P A L  N+CRNPD+   GPWC+TTDP+VR + C++  C 
Sbjct: 397 KCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDAD-KGPWCFTTDPSVRWEYCNLKKCS 455

Query: 188 QDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSK 247
             + +V   P         +P  E C+   G+ Y+G+ A T  G PC  WA   A+   +
Sbjct: 456 GTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWA---AQEPHR 512

Query: 248 HQDF----NSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGL 303
           H  F    N    L +N+CRNPDGD  G WCY       + YCD+  C            
Sbjct: 513 HSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQC------------ 560

Query: 304 DEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR 363
                                      +   DCG +P  E K                GR
Sbjct: 561 --------------------------AAPSFDCG-KPQVEPKK-------------CPGR 580

Query: 364 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 423
           +V G  A     PWQV L  +      CG +LIS  WVLTAAHCL     +K+   +   
Sbjct: 581 VVGGCVAHPHSWPWQVSLRTRFGMH-FCGGTLISPEWVLTAAHCL-----EKSPRPSSYK 634

Query: 424 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 483
           V +G H     E ++++I  + ++++ P         +DIAL+KL  P   +D + P CL
Sbjct: 635 VILGAHQEVNLEPHVQEIE-VSRLFLEP-------TRKDIALLKLSSPAVITDKVIPACL 686

Query: 484 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK--DSTR 541
           P      +     +   +TGWG  + T+ A        +L+   LP++E  VC   +   
Sbjct: 687 PSPNYVVADRTECF---ITGWGETQGTFGA-------GLLKEAQLPVIENKVCNRYEFLN 736

Query: 542 IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYG 601
            R+     CAG+        D+C+GDSGGP V      +++   G+ SWG GC R  K G
Sbjct: 737 GRVQSTELCAGHL---AGGTDSCQGDSGGPLVCFE--KDKYILQGVTSWGLGCARPNKPG 791

Query: 602 FYTHVFRLKKWIQKVI 617
            Y  V R   WI+ V+
Sbjct: 792 VYVRVSRFVTWIEGVM 807



 Score =  130 bits (328), Expect = 3e-30
 Identities = 67/184 (36%), Positives = 87/184 (47%), Gaps = 24/184 (13%)

Query: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
           C  G G NYRG ++ T++GI CQ W S  PH+P  +  THP   L+EN+CRNPD+   GP
Sbjct: 103 CKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGP 162

Query: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAV 227
           WCYTTDP  R   C I  C                        E+C+   G+ Y G+++ 
Sbjct: 163 WCYTTDPEKRYDYCDILECE-----------------------EECMHCSGENYDGKISK 199

Query: 228 TTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCD 287
           T  GL C AW S    A            L +N+CRNPD  E   WC+       +  CD
Sbjct: 200 TMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPD-RELRPWCFTTDPNKRWELCD 258

Query: 288 LNYC 291
           +  C
Sbjct: 259 IPRC 262



 Score =  130 bits (328), Expect = 3e-30
 Identities = 67/184 (36%), Positives = 93/184 (50%), Gaps = 4/184 (2%)

Query: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
           C +G G NYRG+V +T SG  CQ W ++ PH         P  +L EN+CRNPD     P
Sbjct: 275 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGK-RAP 333

Query: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAV 227
           WC+TT+  VR + C IP C  D   V+    +  +   L+P ++ C    GQ Y+G  + 
Sbjct: 334 WCHTTNSQVRWEYCKIPSC--DSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSST 391

Query: 228 TTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCD 287
           TT G  C +W+S       K  +      L  N+CRNPD D +G WC+       + YC+
Sbjct: 392 TTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDAD-KGPWCFTTDPSVRWEYCN 450

Query: 288 LNYC 291
           L  C
Sbjct: 451 LKKC 454



 Score =  124 bits (311), Expect = 3e-28
 Identities = 65/190 (34%), Positives = 92/190 (48%), Gaps = 16/190 (8%)

Query: 105 EGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSST 164
           E  C    G NY G ++ T SG+ECQ W S+ PH      +  P  +L++N+CRNPD   
Sbjct: 182 EEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241

Query: 165 TGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGR 224
             PWC+TTDP  R + C IP C          P S G       P  QC+   G+ Y+G 
Sbjct: 242 R-PWCFTTDPNKRWELCDIPRC-------TTPPPSSG-------PTYQCLKGTGENYRGN 286

Query: 225 LAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFG 284
           +AVT  G  C  W++      ++  +      L EN+CRNPDG +   WC+       + 
Sbjct: 287 VAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDG-KRAPWCHTTNSQVRWE 345

Query: 285 YCDLNYCEEA 294
           YC +  C+ +
Sbjct: 346 YCKIPSCDSS 355



 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 32/104 (30%), Positives = 50/104 (48%)

Query: 210 LEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDE 269
           L +C    G+ Y+G ++ T +G+ C  W+S            + +  L EN+CRNPD D 
Sbjct: 100 LSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDP 159

Query: 270 EGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEG 313
           +G WCY       + YCD+  CEE     +G+  D    + + G
Sbjct: 160 QGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSG 203


>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
          Length = 2040

 Score =  238 bits (606), Expect = 2e-62
 Identities = 176/562 (31%), Positives = 245/562 (43%), Gaps = 108/562 (19%)

Query: 60   CVEETCSYEEAFEALESSTATDV--FWAKYTACETARTPRDKLAACLEGNCAEGLGTNYR 117
            C    CS  E+   LE+ T   V    A   A  T +TP       +   C  G G +YR
Sbjct: 1574 CNLTQCSETES-GVLETPTVVPVPSMEAHSEAAPTEQTP-------VVRQCYHGNGQSYR 1625

Query: 118  GHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVR 177
            G  + T +G  CQ W S  PH+ +     +P   L  N+CRNPD+ T GPWC+T DP++R
Sbjct: 1626 GTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADT-GPWCFTMDPSIR 1684

Query: 178  RQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQ-CVPDRGQQYQGRLAVTTHGLPCLA 236
             + C++  C   + TV + P +     +L PP EQ C+   G+ Y+G+ A T  G PC  
Sbjct: 1685 WEYCNLTRCSDTEGTV-VAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQE 1743

Query: 237  WASAQAKALSKHQDF----NSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCE 292
            WA+ +     +H  F    N    L +N+CRNPDGD  G WCY       F YCD+  C 
Sbjct: 1744 WAAQEPH---RHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLC- 1799

Query: 293  EAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTE 352
                                                  S   DCG +P  E K       
Sbjct: 1800 -------------------------------------ASSSFDCG-KPQVEPKK------ 1815

Query: 353  RELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPP 412
                     G IV G  A     PWQV L R    +  CG +LIS  WVLTAAHCL    
Sbjct: 1816 -------CPGSIVGGCVAHPHSWPWQVSL-RTRFGKHFCGGTLISPEWVLTAAHCL---- 1863

Query: 413  WDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPV 472
              K+   +   V +G H     E ++++I  + ++++ P          DIAL+KL +P 
Sbjct: 1864 -KKSSRPSSYKVILGAHQEVNLESHVQEIE-VSRLFLEP-------TQADIALLKLSRPA 1914

Query: 473  AFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVE 532
              +D + P CLP  +   +     Y   +TGWG  + T+    G G   +L+   L ++E
Sbjct: 1915 VITDKVMPACLPSPDYMVTARTECY---ITGWGETQGTF----GTG---LLKEAQLLVIE 1964

Query: 533  RPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 592
              VC     I       CA +     +  D+C+GDSGGP V      +++   G+ SWG 
Sbjct: 1965 NEVCNHYKYI-------CAEHL---ARGTDSCQGDSGGPLVCFE--KDKYILQGVTSWGL 2012

Query: 593  GCDRDGKYGFYTHVFRLKKWIQ 614
            GC R  K G Y  V R   WI+
Sbjct: 2013 GCARPNKPGVYARVSRFVTWIE 2034



 Score =  131 bits (330), Expect = 2e-30
 Identities = 69/197 (35%), Positives = 95/197 (48%), Gaps = 12/197 (6%)

Query: 107  NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
            +C  G G +YRG  + T +G  CQ W S  PH  +     +P A L EN+CRNPDS    
Sbjct: 1501 DCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQ- 1559

Query: 167  PWCYTTDPTVRRQECSIPVCGQDQVTVAMTP----------RSEGSSVNLSPPLEQCVPD 216
            PWCYTTDP VR + C++  C + +  V  TP           SE +    +P + QC   
Sbjct: 1560 PWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHG 1619

Query: 217  RGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYV 276
             GQ Y+G  + T  G  C +W+S       +  +      L  N+CRNPD D  G WC+ 
Sbjct: 1620 NGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDAD-TGPWCFT 1678

Query: 277  AGKPGDFGYCDLNYCEE 293
                  + YC+L  C +
Sbjct: 1679 MDPSIRWEYCNLTRCSD 1695



 Score =  125 bits (313), Expect = 2e-28
 Identities = 66/197 (33%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 108  CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
            C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD     P
Sbjct: 826  CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDP-VAAP 884

Query: 168  WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217
            +CYT DP+VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 885  YCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGN 944

Query: 218  GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277
            GQ YQG   +T  G  C AW+S    + S+   +     L++N+CRNPD      WCY  
Sbjct: 945  GQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPD-PVAAPWCYTT 1003

Query: 278  GKPGDFGYCDLNYCEEA 294
                 + YC+L  C +A
Sbjct: 1004 DPSVRWEYCNLTRCSDA 1020



 Score =  124 bits (312), Expect = 2e-28
 Identities = 64/187 (34%), Positives = 91/187 (48%), Gaps = 4/187 (2%)

Query: 107  NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
            +C  G G +YRG  + T +G  CQ W S  PH  +  +  +P   L  N+CRNPD+  + 
Sbjct: 1167 DCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIS- 1225

Query: 167  PWCYTTDPTVRRQECSIPVC--GQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGR 224
            PWCYT DP VR + C++  C   +  V    T  SE +    SP ++ C    GQ Y+G 
Sbjct: 1226 PWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGS 1285

Query: 225  LAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFG 284
             + T  G  C +W+S       +  ++     L  N+CRNPD  E   WCY       + 
Sbjct: 1286 FSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA-EIRPWCYTMDPSVRWE 1344

Query: 285  YCDLNYC 291
            YC+L  C
Sbjct: 1345 YCNLTQC 1351



 Score =  122 bits (305), Expect = 1e-27
 Identities = 64/198 (32%), Positives = 95/198 (47%), Gaps = 12/198 (6%)

Query: 107 NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
           +C  G G +YRG  + T +G  CQ W S  PH+    +  +P A L  N+CRNPD +   
Sbjct: 27  DCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRNPD-AVAA 85

Query: 167 PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPD 216
           P+CYT DP VR + C++  C   + T    P           SE +     P +++C   
Sbjct: 86  PYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHG 145

Query: 217 RGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYV 276
            GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY 
Sbjct: 146 NGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYT 204

Query: 277 AGKPGDFGYCDLNYCEEA 294
                 + YC+L  C +A
Sbjct: 205 RDPGVRWEYCNLTQCSDA 222



 Score =  121 bits (304), Expect = 2e-27
 Identities = 66/194 (34%), Positives = 90/194 (46%), Gaps = 12/194 (6%)

Query: 108  CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
            C  G G +Y+G   IT +G  CQ W S  PH        +P A L +N+CRNPD     P
Sbjct: 940  CYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDP-VAAP 998

Query: 168  WCYTTDPTVRRQECSIPVCGQDQVTVAMTPRS----------EGSSVNLSPPLEQCVPDR 217
            WCYTTDP+VR + C++  C   + T  + P            E +    +P ++ C    
Sbjct: 999  WCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHY 1058

Query: 218  GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277
            GQ Y+G  + T  G  C AW+S      S+  +      L  N+CRNPD  E   WCY  
Sbjct: 1059 GQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDA-EIRPWCYTM 1117

Query: 278  GKPGDFGYCDLNYC 291
                 + YC+L  C
Sbjct: 1118 DPSVRWEYCNLTQC 1131



 Score =  121 bits (303), Expect = 2e-27
 Identities = 66/195 (33%), Positives = 93/195 (47%), Gaps = 12/195 (6%)

Query: 107  NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
            +C    G +YRG  + T +G  CQ W S  PH+       +P A L  N+CRNPD+    
Sbjct: 1053 DCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEIR- 1111

Query: 167  PWCYTTDPTVRRQECSIPVCGQDQ------VTVAMTPRSEGSS----VNLSPPLEQCVPD 216
            PWCYT DP+VR + C++  C   +      +TV   P +E SS       SP ++ C   
Sbjct: 1112 PWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYHG 1171

Query: 217  RGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYV 276
             GQ Y+G  + T  G  C +W+S       +  ++     L  N+CRNPD  E   WCY 
Sbjct: 1172 DGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA-EISPWCYT 1230

Query: 277  AGKPGDFGYCDLNYC 291
                  + YC+L  C
Sbjct: 1231 MDPNVRWEYCNLTQC 1245



 Score =  120 bits (301), Expect = 4e-27
 Identities = 66/197 (33%), Positives = 95/197 (48%), Gaps = 12/197 (6%)

Query: 107  NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
            +C  G G +YRG ++ T +G  CQ W S  PH        +P A L  N+CRNPD+    
Sbjct: 1387 DCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIR- 1445

Query: 167  PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPD 216
            PWCYT DP+VR + C++  C   + +V  TP           SE +    SP ++ C   
Sbjct: 1446 PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHG 1505

Query: 217  RGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYV 276
             G+ Y+G  + T  G  C +W+S       +  +      L EN+CRNPD  ++  WCY 
Sbjct: 1506 DGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQ-PWCYT 1564

Query: 277  AGKPGDFGYCDLNYCEE 293
                  + YC+L  C E
Sbjct: 1565 TDPCVRWEYCNLTQCSE 1581



 Score =  120 bits (300), Expect = 5e-27
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD+    P
Sbjct: 142 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAP 200

Query: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 201 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 260

Query: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 261 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTR 319

Query: 278 GKPGDFGYCDLNYCEEA 294
                + YC+L  C +A
Sbjct: 320 DPGVRWEYCNLTQCSDA 336



 Score =  120 bits (300), Expect = 5e-27
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD +   P
Sbjct: 256 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAP 314

Query: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 315 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 374

Query: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 375 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTR 433

Query: 278 GKPGDFGYCDLNYCEEA 294
                + YC+L  C +A
Sbjct: 434 DPGVRWEYCNLTQCSDA 450



 Score =  120 bits (300), Expect = 5e-27
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD+    P
Sbjct: 370 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAP 428

Query: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 429 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 488

Query: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 489 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTR 547

Query: 278 GKPGDFGYCDLNYCEEA 294
                + YC+L  C +A
Sbjct: 548 DPGVRWEYCNLTQCSDA 564



 Score =  120 bits (300), Expect = 5e-27
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD +   P
Sbjct: 484 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAP 542

Query: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 543 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 602

Query: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 603 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTR 661

Query: 278 GKPGDFGYCDLNYCEEA 294
                + YC+L  C +A
Sbjct: 662 DPGVRWEYCNLTQCSDA 678



 Score =  120 bits (300), Expect = 5e-27
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD+    P
Sbjct: 598 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAP 656

Query: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 657 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 716

Query: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 717 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTR 775

Query: 278 GKPGDFGYCDLNYCEEA 294
                + YC+L  C +A
Sbjct: 776 DPGVRWEYCNLTQCSDA 792



 Score =  120 bits (300), Expect = 5e-27
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD +   P
Sbjct: 712 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAP 770

Query: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 771 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 830

Query: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 831 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPD-PVAAPYCYTR 889

Query: 278 GKPGDFGYCDLNYCEEA 294
                + YC+L  C +A
Sbjct: 890 DPSVRWEYCNLTQCSDA 906



 Score =  118 bits (295), Expect = 2e-26
 Identities = 65/195 (33%), Positives = 92/195 (47%), Gaps = 12/195 (6%)

Query: 107  NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
            +C  G G +YRG  + T +G  CQ W S  PH  +  +  +P   L  N+CRNPD+    
Sbjct: 1273 DCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIR- 1331

Query: 167  PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPD 216
            PWCYT DP+VR + C++  C   + T+  TP           SE +    S  ++ C   
Sbjct: 1332 PWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRG 1391

Query: 217  RGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYV 276
             GQ Y+G L+ T  G  C +W+S       +   +     L  N+CRNPD  E   WCY 
Sbjct: 1392 DGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDA-EIRPWCYT 1450

Query: 277  AGKPGDFGYCDLNYC 291
                  + YC+L  C
Sbjct: 1451 MDPSVRWEYCNLTRC 1465



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 210 LEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDE 269
           ++ C    GQ Y+G  + T  G  C AW+S      ++  +      L+ N+CRNPD   
Sbjct: 25  VQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRNPDA-V 83

Query: 270 EGVWCYVAGKPGDFGYCDLNYCEEA 294
              +CY       + YC+L  C +A
Sbjct: 84  AAPYCYTRDPGVRWEYCNLTQCSDA 108


>gi|4506115 protein C [Homo sapiens]
          Length = 461

 Score =  179 bits (454), Expect = 7e-45
 Identities = 108/272 (39%), Positives = 151/272 (55%), Gaps = 18/272 (6%)

Query: 343 EKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVL 402
           EKK    K + E  E  +D R+++G     G SPWQV+L   S ++L CGA LI   WVL
Sbjct: 191 EKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLL-DSKKKLACGAVLIHPSWVL 249

Query: 403 TAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRD 462
           TAAHC+     D++     LLVR+G++   R+E+  E    ++++++HP Y+ +   D D
Sbjct: 250 TAAHCM-----DES---KKLLVRLGEYDLRRWEK-WELDLDIKEVFVHPNYS-KSTTDND 299

Query: 463 IALMKLKKPVAFSDYIHPVCLPDRETAA-SLLQAGYKGRVTGWGNLKETWTANVGKGQPS 521
           IAL+ L +P   S  I P+CLPD   A   L QAG +  VTGWG    +      + +  
Sbjct: 300 IALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWG-YHSSREKEAKRNRTF 358

Query: 522 VLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNR 581
           VL  + +P+V    C +     +++NM CAG     G R DACEGDSGGP V  + F+  
Sbjct: 359 VLNFIKIPVVPHNECSEVMSNMVSENMLCAGIL---GDRQDACEGDSGGPMV--ASFHGT 413

Query: 582 WYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWI 613
           W+ +G+VSWGEGC     YG YT V R   WI
Sbjct: 414 WFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWI 445



 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 35/92 (38%), Positives = 55/92 (59%), Gaps = 4/92 (4%)

Query: 27  VFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAK 86
           VF + ++A  +L+  +RAN+FLEE+R  +LEREC+EE C +EEA E  ++   T  FW+K
Sbjct: 26  VFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSK 85

Query: 87  YTACETART-PRDKLAA---CLEGNCAEGLGT 114
           +   +     P +   A   C  G C +G+G+
Sbjct: 86  HVDGDQCLVLPLEHPCASLCCGHGTCIDGIGS 117


>gi|4503625 coagulation factor X preproprotein [Homo sapiens]
          Length = 488

 Score =  174 bits (440), Expect = 3e-43
 Identities = 102/254 (40%), Positives = 144/254 (56%), Gaps = 24/254 (9%)

Query: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 422
           RIV G + + G  PWQ +L  +   E  CG +++S+ ++LTAAHCL        +     
Sbjct: 234 RIVGGQECKDGECPWQALLINEE-NEGFCGGTILSEFYILTAAHCL--------YQAKRF 284

Query: 423 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 482
            VR+G  + T  E   E +  +E +  H R+  +E  D DIA+++LK P+ F   + P C
Sbjct: 285 KVRVGDRN-TEQEEGGEAVHEVEVVIKHNRFT-KETYDFDIAVLRLKTPITFRMNVAPAC 342

Query: 483 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSV-LQVVNLPIVERPVCKDSTR 541
           LP+R+ A S L     G V+G+G   E       KG+ S  L+++ +P V+R  CK S+ 
Sbjct: 343 LPERDWAESTLMTQKTGIVSGFGRTHE-------KGRQSTRLKMLEVPYVDRNSCKLSSS 395

Query: 542 IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYG 601
             IT NMFCAGY   + K+ DAC+GDSGGP V +  F + ++  GIVSWGEGC R GKYG
Sbjct: 396 FIITQNMFCAGY---DTKQEDACQGDSGGPHVTR--FKDTYFVTGIVSWGEGCARKGKYG 450

Query: 602 FYTHVFRLKKWIQK 615
            YT V    KWI +
Sbjct: 451 IYTKVTAFLKWIDR 464



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 46/96 (47%), Positives = 62/96 (64%), Gaps = 10/96 (10%)

Query: 21  LVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTAT 80
           L+  + +F+  +QA ++L RV RAN+FLEE++KG+LEREC+EETCSYEEA E  E S  T
Sbjct: 18  LLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKT 77

Query: 81  DVFWAKY---TACETARTPRDKLAACLEGNCAEGLG 113
           + FW KY     CET+           +G C +GLG
Sbjct: 78  NEFWNKYKDGDQCETSPCQN-------QGKCKDGLG 106


>gi|4503649 coagulation factor IX preproprotein [Homo sapiens]
          Length = 461

 Score =  161 bits (407), Expect = 2e-39
 Identities = 97/255 (38%), Positives = 147/255 (57%), Gaps = 26/255 (10%)

Query: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 422
           R+V G DA+ G  PWQV+L  K   +  CG S+++++W++TAAHC+         T   +
Sbjct: 226 RVVGGEDAKPGQFPWQVVLNGKV--DAFCGGSIVNEKWIVTAAHCVE--------TGVKI 275

Query: 423 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWREN-LDRDIALMKLKKPVAFSDYIHPV 481
            V  G+H+    E   +K +++ +I  H  YN   N  + DIAL++L +P+  + Y+ P+
Sbjct: 276 TVVAGEHNIEETEHTEQKRNVI-RIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPI 334

Query: 482 CLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPS-VLQVVNLPIVERPVCKDST 540
           C+ D+E     L+ G  G V+GWG +         KG+ + VLQ + +P+V+R  C  ST
Sbjct: 335 CIADKEYTNIFLKFG-SGYVSGWGRVFH-------KGRSALVLQYLRVPLVDRATCLRST 386

Query: 541 RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY 600
           +  I +NMFCAG+   EG R D+C+GDSGGP V +    +  +  GI+SWGE C   GKY
Sbjct: 387 KFTIYNNMFCAGFH--EGGR-DSCQGDSGGPHVTEVEGTS--FLTGIISWGEECAMKGKY 441

Query: 601 GFYTHVFRLKKWIQK 615
           G YT V R   WI++
Sbjct: 442 GIYTKVSRYVNWIKE 456



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 44/127 (34%), Positives = 63/127 (49%), Gaps = 13/127 (10%)

Query: 10  PGCLALAALCSLVHSQ-HVFLAPQQARSLLQRVRRANTF-LEEVRKGNLERECVEETCSY 67
           PG + +  L  L+ ++  VFL  + A  +L R +R N+  LEE  +GNLEREC+EE CS+
Sbjct: 12  PGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCSF 71

Query: 68  EEAFEALESSTATDVFWAKYT---ACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITR 124
           EEA E  E++  T  FW +Y     CE+          CL G   +    +Y        
Sbjct: 72  EEAREVFENTERTTEFWKQYVDGDQCES--------NPCLNGGSCKDDINSYECWCPFGF 123

Query: 125 SGIECQL 131
            G  C+L
Sbjct: 124 EGKNCEL 130


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  157 bits (398), Expect = 2e-38
 Identities = 99/296 (33%), Positives = 158/296 (53%), Gaps = 26/296 (8%)

Query: 328 TFGSGEADCGLRPLFE---KKSLEDKTERELLESYIDG---RIVEGSDAEIGMSPWQVML 381
           TF   +  C  +P  +   +    D ++ E  +  + G   RIV G+ +  G  PWQ  L
Sbjct: 535 TFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASL 594

Query: 382 FRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKI 441
             +     +CG +LI+DRWV+TAAHC               L ++ ++SR   E + +  
Sbjct: 595 QVRGRH--ICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFK-- 650

Query: 442 SMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRV 501
             + ++ +HP Y+  ++ D D+AL++L  PV  S  + PVCLP R   +   + G    +
Sbjct: 651 --VSRLLLHP-YHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPAR---SHFFEPGLHCWI 704

Query: 502 TGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRG 561
           TGWG L+E      G    + LQ V++ ++ + +C +  R ++T  M CAGY+  +GK+ 
Sbjct: 705 TGWGALRE------GGPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYR--KGKK- 755

Query: 562 DACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVI 617
           DAC+GDSGGP V K+  + RW+  G+VSWG GC R   +G YT +  +  WIQ+V+
Sbjct: 756 DACQGDSGGPLVCKA-LSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVV 810


>gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
           sapiens]
          Length = 723

 Score =  156 bits (394), Expect = 6e-38
 Identities = 144/566 (25%), Positives = 223/566 (39%), Gaps = 102/566 (18%)

Query: 103 CLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDS 162
           C E  C    G +YRG ++ T SG  CQ W  + PH+ +     +P     +N+CRNPD 
Sbjct: 201 CSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 260

Query: 163 STTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLE--QCVPDRGQQ 220
               PWCYT DP  R + C+I  C  + +             +   PLE  +C+  +G+ 
Sbjct: 261 QPR-PWCYTLDPHTRWEYCAIKTCADNTMN------------DTDVPLETTECIQGQGEG 307

Query: 221 YQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKP 280
           Y+G +    +G+PC  W S          +      L EN+CRNPDG E   WC+     
Sbjct: 308 YRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESP-WCFTTDPN 366

Query: 281 GDFGY------CDLNYCEEAVE----------EETGDGLD--------EDSDRAIEGRTA 316
              GY      CD+++ ++              +T  GL         ED  R I     
Sbjct: 367 IRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPD 426

Query: 317 TSEYQTFF--NPRTFGSGEADCGLRPLFEKKSLE-DKTERELLESYIDG----------- 362
            S+    +  NP     G       PL         + E +   + ++            
Sbjct: 427 ASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTK 486

Query: 363 --RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 420
             R+V G      +  W V L  ++    +CG SLI + WVLTA  C  +P  D      
Sbjct: 487 QLRVVNGIPTRTNIG-WMVSLRYRNKH--ICGGSLIKESWVLTARQC--FPSRDL----K 537

Query: 421 DLLVRIGKHS-RTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 479
           D    +G H    R +   +++  + ++   P          D+ LMKL +P    D++ 
Sbjct: 538 DYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPE-------GSDLVLMKLARPAVLDDFVS 590

Query: 480 PVCLPD------RETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 533
            + LP+       +T+ S+   GY G +   G                +L+V +L I+  
Sbjct: 591 TIDLPNYGCTIPEKTSCSVYGWGYTGLINYDG----------------LLRVAHLYIMGN 634

Query: 534 PVCKDSTRIRIT--DNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 591
             C    R ++T  ++  CAG    E      CEGD GGP V +   +     +G++  G
Sbjct: 635 EKCSQHHRGKVTLNESEICAG---AEKIGSGPCEGDYGGPLVCEQ--HKMRMVLGVIVPG 689

Query: 592 EGCDRDGKYGFYTHVFRLKKWIQKVI 617
            GC    + G +  V    KWI K+I
Sbjct: 690 RGCAIPNRPGIFVRVAYYAKWIHKII 715



 Score =  115 bits (287), Expect = 2e-25
 Identities = 62/193 (32%), Positives = 89/193 (46%), Gaps = 28/193 (14%)

Query: 107 NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
           NC  G G +Y+G V+IT+SGI+CQ W S  PH+      ++ G DLQEN+CRNP     G
Sbjct: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNPRGEEGG 181

Query: 167 PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLA 226
           PWC+T++P VR + C IP C +                       +C+   G+ Y+G + 
Sbjct: 182 PWCFTSNPEVRYEVCDIPQCSE----------------------VECMTCNGESYRGLMD 219

Query: 227 VTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYC 286
            T  G  C  W            +        +N+CRNPDG +   WCY       + YC
Sbjct: 220 HTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG-QPRPWCYTLDPHTRWEYC 278

Query: 287 DLNYCEEAVEEET 299
            +  C +    +T
Sbjct: 279 AIKTCADNTMNDT 291



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 5/84 (5%)

Query: 210 LEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDE 269
           +  C+  +G+ Y+G +++T  G+ C  W+S     +  H+       L EN+CRNP G+E
Sbjct: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSS-----MIPHEHSYRGKDLQENYCRNPRGEE 179

Query: 270 EGVWCYVAGKPGDFGYCDLNYCEE 293
            G WC+ +     +  CD+  C E
Sbjct: 180 GGPWCFTSNPEVRYEVCDIPQCSE 203


>gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Homo
           sapiens]
          Length = 728

 Score =  156 bits (394), Expect = 6e-38
 Identities = 144/566 (25%), Positives = 223/566 (39%), Gaps = 102/566 (18%)

Query: 103 CLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDS 162
           C E  C    G +YRG ++ T SG  CQ W  + PH+ +     +P     +N+CRNPD 
Sbjct: 206 CSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 265

Query: 163 STTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLE--QCVPDRGQQ 220
               PWCYT DP  R + C+I  C  + +             +   PLE  +C+  +G+ 
Sbjct: 266 QPR-PWCYTLDPHTRWEYCAIKTCADNTMN------------DTDVPLETTECIQGQGEG 312

Query: 221 YQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKP 280
           Y+G +    +G+PC  W S          +      L EN+CRNPDG E   WC+     
Sbjct: 313 YRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESP-WCFTTDPN 371

Query: 281 GDFGY------CDLNYCEEAVE----------EETGDGLD--------EDSDRAIEGRTA 316
              GY      CD+++ ++              +T  GL         ED  R I     
Sbjct: 372 IRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPD 431

Query: 317 TSEYQTFF--NPRTFGSGEADCGLRPLFEKKSLE-DKTERELLESYIDG----------- 362
            S+    +  NP     G       PL         + E +   + ++            
Sbjct: 432 ASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTK 491

Query: 363 --RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 420
             R+V G      +  W V L  ++    +CG SLI + WVLTA  C  +P  D      
Sbjct: 492 QLRVVNGIPTRTNIG-WMVSLRYRNKH--ICGGSLIKESWVLTARQC--FPSRDL----K 542

Query: 421 DLLVRIGKHS-RTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 479
           D    +G H    R +   +++  + ++   P          D+ LMKL +P    D++ 
Sbjct: 543 DYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPE-------GSDLVLMKLARPAVLDDFVS 595

Query: 480 PVCLPD------RETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 533
            + LP+       +T+ S+   GY G +   G                +L+V +L I+  
Sbjct: 596 TIDLPNYGCTIPEKTSCSVYGWGYTGLINYDG----------------LLRVAHLYIMGN 639

Query: 534 PVCKDSTRIRIT--DNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 591
             C    R ++T  ++  CAG    E      CEGD GGP V +   +     +G++  G
Sbjct: 640 EKCSQHHRGKVTLNESEICAG---AEKIGSGPCEGDYGGPLVCEQ--HKMRMVLGVIVPG 694

Query: 592 EGCDRDGKYGFYTHVFRLKKWIQKVI 617
            GC    + G +  V    KWI K+I
Sbjct: 695 RGCAIPNRPGIFVRVAYYAKWIHKII 720



 Score =  120 bits (300), Expect = 5e-27
 Identities = 62/193 (32%), Positives = 90/193 (46%), Gaps = 23/193 (11%)

Query: 107 NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
           NC  G G +Y+G V+IT+SGI+CQ W S  PH+     +++ G DLQEN+CRNP     G
Sbjct: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG 186

Query: 167 PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLA 226
           PWC+T++P VR + C IP C +                       +C+   G+ Y+G + 
Sbjct: 187 PWCFTSNPEVRYEVCDIPQCSE----------------------VECMTCNGESYRGLMD 224

Query: 227 VTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYC 286
            T  G  C  W            +        +N+CRNPDG +   WCY       + YC
Sbjct: 225 HTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG-QPRPWCYTLDPHTRWEYC 283

Query: 287 DLNYCEEAVEEET 299
            +  C +    +T
Sbjct: 284 AIKTCADNTMNDT 296



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 26/84 (30%), Positives = 42/84 (50%)

Query: 210 LEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDE 269
           +  C+  +G+ Y+G +++T  G+ C  W+S      S          L EN+CRNP G+E
Sbjct: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEE 184

Query: 270 EGVWCYVAGKPGDFGYCDLNYCEE 293
            G WC+ +     +  CD+  C E
Sbjct: 185 GGPWCFTSNPEVRYEVCDIPQCSE 208


>gi|4504383 HGF activator preproprotein [Homo sapiens]
          Length = 655

 Score =  156 bits (394), Expect = 6e-38
 Identities = 139/464 (29%), Positives = 192/464 (41%), Gaps = 76/464 (16%)

Query: 168 WCYTT-------DPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQ 220
           WC  T        P +    C + V     V  A  P   G   N+ P  E+C    G  
Sbjct: 236 WCEGTRHTACLSSPCLNGGTCHLIVATGTTVC-ACPPGFAGRLCNIEPD-ERCFLGNGTG 293

Query: 221 YQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLV----ENFCRNPDGDEEGVWCYV 276
           Y+G  + +  GL CLAW S        H D   A  L+      +CRNPD DE   WCYV
Sbjct: 294 YRGVASTSASGLSCLAWNS-DLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERP-WCYV 351

Query: 277 AGKPG-DFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEAD 335
                  + YC L  CE     +    L            AT        P     G   
Sbjct: 352 VKDSALSWEYCRLEACESLTRVQLSPDL-----------LATL-------PEPASPGRQA 393

Query: 336 CGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASL 395
           CG R    KK            +++  RI+ GS +  G  PW   ++     +  C  SL
Sbjct: 394 CGRR---HKK-----------RTFLRPRIIGGSSSLPGSHPWLAAIYIG---DSFCAGSL 436

Query: 396 ISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNW 455
           +   WV++AAHC  + P       + + V +G+H   R   ++ +   +EK   +  Y+ 
Sbjct: 437 VHTCWVVSAAHCFSHSP-----PRDSVSVVLGQHFFNR-TTDVTQTFGIEKYIPYTLYSV 490

Query: 456 RENLDRDIALMKLKKP----VAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETW 511
               D D+ L++LKK        S ++ P+CLP+     S   AG+K ++ GWG+L E  
Sbjct: 491 FNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPE---PGSTFPAGHKCQIAGWGHLDE-- 545

Query: 512 TANVGKGQPSVLQVVNLPIVERPVCKDST--RIRITDNMFCAGYKPDEGKRGDACEGDSG 569
             NV  G  S L+   +P+V    C         I+ NM CAGY      + DAC+GDSG
Sbjct: 546 --NVS-GYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDC---KSDACQGDSG 599

Query: 570 GPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWI 613
           GP   +   N   Y  GI+SWG+GC R  K G YT V     WI
Sbjct: 600 GPLACEK--NGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWI 641



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 37/125 (29%), Positives = 54/125 (43%), Gaps = 22/125 (17%)

Query: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADL----QENFCRNPDSS 163
           C  G GT YRG  + + SG+ C  W S   ++ E++  +   A L       +CRNPD+ 
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQ-ELHVDSVGAAALLGLGPHAYCRNPDND 344

Query: 164 TTGPWCYTT-DPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPD---RGQ 219
              PWCY   D  +  + C +  C               + V LSP L   +P+    G+
Sbjct: 345 ER-PWCYVVKDSALSWEYCRLEAC------------ESLTRVQLSPDLLATLPEPASPGR 391

Query: 220 QYQGR 224
           Q  GR
Sbjct: 392 QACGR 396


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score =  153 bits (387), Expect = 4e-37
 Identities = 104/284 (36%), Positives = 145/284 (51%), Gaps = 40/284 (14%)

Query: 335 DCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGAS 394
           +CG RP  EK +                R+V G  A  G  PWQV L  K      CGA+
Sbjct: 491 ECGARPAMEKPT----------------RVVGGFGAASGEVPWQVSL--KEGSRHFCGAT 532

Query: 395 LISDRWVLTAAHCLLYPPWDKNFTE-NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRY 453
           ++ DRW+L+AAHC        N T+   +   +G  S      +  KI  L ++ +HP Y
Sbjct: 533 VVGDRWLLSAAHCF-------NHTKVEQVRAHLGTASLLGLGGSPVKIG-LRRVVLHPLY 584

Query: 454 NWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTA 513
           N    LD D+A+++L  P+AF+ YI PVCLP    A      G K  ++GWGN +E    
Sbjct: 585 N-PGILDFDLAVLELASPLAFNKYIQPVCLP---LAIQKFPVGRKCMISGWGNTQE---G 637

Query: 514 NVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFV 573
           N  K  P +LQ  ++ I+++  C       +TD M CAG+   EGK  D+C+GDSGGP  
Sbjct: 638 NATK--PELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFL--EGKV-DSCQGDSGGPLA 692

Query: 574 MKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVI 617
            +      +Y  GIVSWG GC +  K G YT + RLK WI +++
Sbjct: 693 CEEA-PGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIM 735



 Score =  146 bits (368), Expect = 6e-35
 Identities = 97/286 (33%), Positives = 149/286 (52%), Gaps = 39/286 (13%)

Query: 330 GSGEA--DCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQ 387
           GS EA  +CGL+P +                 + GRIV G +A  G  PWQ  L  +  +
Sbjct: 183 GSDEAHCECGLQPAWR----------------MAGRIVGGMEASPGEFPWQASL--RENK 224

Query: 388 ELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKI 447
           E  CGA++I+ RW+++AAHC     +++       +  +G    +  E +  +  +++ I
Sbjct: 225 EHFCGAAIINARWLVSAAHC-----FNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQ-I 278

Query: 448 YIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNL 507
             HP YN  +  D D+A+++L  P+ F  +I PVCLP    A  +     K  ++GWG L
Sbjct: 279 VKHPLYN-ADTADFDVAVLELTSPLPFGRHIQPVCLP---AATHIFPPSKKCLISGWGYL 334

Query: 508 KETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGD 567
           KE +       +P VLQ   + ++++ +C       +TD M CAGY   +GK  D+C+GD
Sbjct: 335 KEDFLV-----KPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYL--DGKV-DSCQGD 386

Query: 568 SGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWI 613
           SGGP V + P + R++  GIVSWG GC    + G Y  V RL+ WI
Sbjct: 387 SGGPLVCEEP-SGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWI 431



 Score =  136 bits (342), Expect = 7e-32
 Identities = 89/257 (34%), Positives = 133/257 (51%), Gaps = 23/257 (8%)

Query: 363  RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 422
            RIV GS A  G  PWQV L+ +  +E  CGA L+++RW+L+AAHC     +D        
Sbjct: 826  RIVGGSAAGRGEWPWQVSLWLRR-REHRCGAVLVAERWLLSAAHC-----FDVYGDPKQW 879

Query: 423  LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 482
               +G    +  E  +E+++   +IY HP YN    LD D+AL++L  PV  S  + P+C
Sbjct: 880  AAFLGTPFLSGAEGQLERVA---RIYKHPFYNLY-TLDYDVALLELAGPVRRSRLVRPIC 935

Query: 483  LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 542
            LP+    A     G +  +TGWG+++E      G      LQ   + ++    C+    +
Sbjct: 936  LPE---PAPRPPDGTRCVITGWGSVRE------GGSMARQLQKAAVRLLSEQTCRRFYPV 986

Query: 543  RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGF 602
            +I+  M CAG+ P  G   D+C GD+GGP   + P + RW   G+ SWG GC R    G 
Sbjct: 987  QISSRMLCAGF-PQGGV--DSCSGDAGGPLACREP-SGRWVLTGVTSWGYGCGRPHFPGV 1042

Query: 603  YTHVFRLKKWIQKVIDQ 619
            YT V  ++ WI + I +
Sbjct: 1043 YTRVAAVRGWIGQHIQE 1059


>gi|11415040 matriptase [Homo sapiens]
          Length = 855

 Score =  151 bits (382), Expect = 2e-36
 Identities = 108/353 (30%), Positives = 168/353 (47%), Gaps = 21/353 (5%)

Query: 266 DGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFN 325
           + DE+G  C         G C     +   +++ GDG DE S   +   T T       N
Sbjct: 517 NSDEQGCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLN 576

Query: 326 PRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKS 385
                 G  +C  +      S E   +  L       R+V G+DA+ G  PWQV L    
Sbjct: 577 GLCLSKGNPECDGKEDCSDGSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALG 636

Query: 386 PQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND---LLVRIGKHSRTRYERNIEKIS 442
            Q  +CGASLIS  W+++AAHC +    D+ F  +D       +G H +++      +  
Sbjct: 637 -QGHICGASLISPNWLVSAAHCYID---DRGFRYSDPTQWTAFLGLHDQSQRSAPGVQER 692

Query: 443 MLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVT 502
            L++I  HP +N     D DIAL++L+KP  +S  + P+CLPD   A+ +  AG    VT
Sbjct: 693 RLKRIISHPFFN-DFTFDYDIALLELEKPAEYSSMVRPICLPD---ASHVFPAGKAIWVT 748

Query: 503 GWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGD 562
           GWG+ +   T  +      +LQ   + ++ +  C++    +IT  M C G+        D
Sbjct: 749 GWGHTQYGGTGAL------ILQKGEIRVINQTTCENLLPQQITPRMMCVGFLSGGV---D 799

Query: 563 ACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQK 615
           +C+GDSGGP +     + R +Q G+VSWG+GC +  K G YT +   + WI++
Sbjct: 800 SCQGDSGGP-LSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKE 851


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  149 bits (377), Expect = 6e-36
 Identities = 95/265 (35%), Positives = 133/265 (50%), Gaps = 29/265 (10%)

Query: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 422
           RI  GS A  G  PWQV +  +     +CG SL+S++WVL+AAHC     +     +   
Sbjct: 44  RITGGSSAVAGQWPWQVSITYEGVH--VCGGSLVSEQWVLSAAHC-----FPSEHHKEAY 96

Query: 423 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 482
            V++G H    Y  +  K+S L+ I  HP Y  +E    DIAL++L +P+ FS YI P+C
Sbjct: 97  EVKLGAHQLDSYSEDA-KVSTLKDIIPHPSY-LQEGSQGDIALLQLSRPITFSRYIRPIC 154

Query: 483 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 542
           LP    A +    G    VTGWG++      +V    P  LQ + +P++ R  C     I
Sbjct: 155 LP---AANASFPNGLHCTVTGWGHV----APSVSLLTPKPLQQLEVPLISRETCNCLYNI 207

Query: 543 R--------ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGC 594
                    + ++M CAGY   EG + DAC+GDSGGP  +  P    WY  GIVSWG+ C
Sbjct: 208 DAKPEEPHFVQEDMVCAGYV--EGGK-DACQGDSGGP--LSCPVEGLWYLTGIVSWGDAC 262

Query: 595 DRDGKYGFYTHVFRLKKWIQKVIDQ 619
               + G YT       WIQ  + +
Sbjct: 263 GARNRPGVYTLASSYASWIQSKVTE 287


>gi|10518503 coagulation factor VII isoform b precursor [Homo
           sapiens]
          Length = 444

 Score =  149 bits (375), Expect = 1e-35
 Identities = 99/291 (34%), Positives = 153/291 (52%), Gaps = 37/291 (12%)

Query: 333 EADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCG 392
           E  CG  P+ EK++           S   GRIV G     G  PWQV+L     Q  LCG
Sbjct: 170 EYPCGKIPILEKRNA----------SKPQGRIVGGKVCPKGECPWQVLLLVNGAQ--LCG 217

Query: 393 ASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPR 452
            +LI+  WV++AAHC     +DK     +L+  +G+H  + ++ + E+   + ++ I   
Sbjct: 218 GTLINTIWVVSAAHC-----FDKIKNWRNLIAVLGEHDLSEHDGD-EQSRRVAQVIIPST 271

Query: 453 YNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWT 512
           Y      + DIAL++L +PV  +D++ P+CLP+R  +   L       V+GWG L +   
Sbjct: 272 YV-PGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLD--- 327

Query: 513 ANVGKGQPSV-LQVVNLPIVERPVCKDSTRI-----RITDNMFCAGYKPDEGKRGDACEG 566
               +G  ++ L V+N+P +    C   +R       IT+ MFCAGY   +G + D+C+G
Sbjct: 328 ----RGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYS--DGSK-DSCKG 380

Query: 567 DSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVI 617
           DSGGP    + +   WY  GIVSWG+GC   G +G YT V +  +W+QK++
Sbjct: 381 DSGGPHA--THYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLM 429



 Score = 73.2 bits (178), Expect = 7e-13
 Identities = 38/79 (48%), Positives = 50/79 (63%), Gaps = 4/79 (5%)

Query: 14 ALAALCSLVHSQH----VFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEE 69
          AL  LC L+  Q     VF+  ++A  +L R RRAN FLEE+R G+LEREC EE CS+EE
Sbjct: 5  ALRLLCLLLGLQGCLAAVFVTQEEAHGVLHRRRRANAFLEELRPGSLERECKEEQCSFEE 64

Query: 70 AFEALESSTATDVFWAKYT 88
          A E  + +  T +FW  Y+
Sbjct: 65 AREIFKDAERTKLFWISYS 83


>gi|4503645 coagulation factor VII isoform a precursor [Homo
           sapiens]
          Length = 466

 Score =  149 bits (375), Expect = 1e-35
 Identities = 99/291 (34%), Positives = 153/291 (52%), Gaps = 37/291 (12%)

Query: 333 EADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCG 392
           E  CG  P+ EK++           S   GRIV G     G  PWQV+L     Q  LCG
Sbjct: 192 EYPCGKIPILEKRNA----------SKPQGRIVGGKVCPKGECPWQVLLLVNGAQ--LCG 239

Query: 393 ASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPR 452
            +LI+  WV++AAHC     +DK     +L+  +G+H  + ++ + E+   + ++ I   
Sbjct: 240 GTLINTIWVVSAAHC-----FDKIKNWRNLIAVLGEHDLSEHDGD-EQSRRVAQVIIPST 293

Query: 453 YNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWT 512
           Y      + DIAL++L +PV  +D++ P+CLP+R  +   L       V+GWG L +   
Sbjct: 294 YV-PGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLD--- 349

Query: 513 ANVGKGQPSV-LQVVNLPIVERPVCKDSTRI-----RITDNMFCAGYKPDEGKRGDACEG 566
               +G  ++ L V+N+P +    C   +R       IT+ MFCAGY   +G + D+C+G
Sbjct: 350 ----RGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYS--DGSK-DSCKG 402

Query: 567 DSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVI 617
           DSGGP    + +   WY  GIVSWG+GC   G +G YT V +  +W+QK++
Sbjct: 403 DSGGPHA--THYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLM 451



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 11/93 (11%)

Query: 7   LQLPGCLALAALCSLVHSQ-----------HVFLAPQQARSLLQRVRRANTFLEEVRKGN 55
           L L GCLA   +      +            VF+  ++A  +L R RRAN FLEE+R G+
Sbjct: 13  LGLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRRANAFLEELRPGS 72

Query: 56  LERECVEETCSYEEAFEALESSTATDVFWAKYT 88
           LEREC EE CS+EEA E  + +  T +FW  Y+
Sbjct: 73  LERECKEEQCSFEEAREIFKDAERTKLFWISYS 105


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score =  148 bits (374), Expect = 1e-35
 Identities = 90/266 (33%), Positives = 140/266 (52%), Gaps = 22/266 (8%)

Query: 353  RELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPP 412
            ++L    I  +IV GS+A+ G  PW V L+      LLCGASL+S  W+++AAHC+    
Sbjct: 774  KKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGG--RLLCGASLVSSDWLVSAAHCV---- 827

Query: 413  WDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPV 472
            + +N   +     +G H ++          ++++I I+P YN R   D DIA+M L+  V
Sbjct: 828  YGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYN-RRRKDNDIAMMHLEFKV 886

Query: 473  AFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVE 532
             ++DYI P+CLP+      +   G    + GWG +    T        ++LQ  ++P++ 
Sbjct: 887  NYTDYIQPICLPEEN---QVFPPGRNCSIAGWGTVVYQGTT------ANILQEADVPLLS 937

Query: 533  RPVCKDST-RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 591
               C+       IT+NM CAGY  +EG   D+C+GDSGGP + +   NNRW+  G+ S+G
Sbjct: 938  NERCQQQMPEYNITENMICAGY--EEGGI-DSCQGDSGGPLMCQE--NNRWFLAGVTSFG 992

Query: 592  EGCDRDGKYGFYTHVFRLKKWIQKVI 617
              C    + G Y  V R  +WIQ  +
Sbjct: 993  YKCALPNRPGVYARVSRFTEWIQSFL 1018


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  147 bits (372), Expect = 2e-35
 Identities = 98/254 (38%), Positives = 138/254 (54%), Gaps = 25/254 (9%)

Query: 363 RIVEGSDAEIGMSPWQVMLFRK-SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 421
           RIV G+++  G  PWQV L  K + Q  LCG SLI  +WVLTAAHC    P    +    
Sbjct: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449

Query: 422 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 481
            ++ +   ++          S +++I IH  Y   E  + DIAL+KL+ P+ ++++  P+
Sbjct: 450 GILNLSDITKDT------PFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPI 502

Query: 482 CLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQ-PSVLQVVNLPIVERPVCKDST 540
           CLP +   +++    +   VTGWG  KE       KG+  ++LQ VN+P+V    C+   
Sbjct: 503 CLPSKGDTSTIYTNCW---VTGWGFSKE-------KGEIQNILQKVNIPLVTNEECQKRY 552

Query: 541 R-IRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 599
           +  +IT  M CAGYK  EG + DAC+GDSGGP V K   N  W  +GI SWGEGC R  +
Sbjct: 553 QDYKITQRMVCAGYK--EGGK-DACKGDSGGPLVCKH--NGMWRLVGITSWGEGCARREQ 607

Query: 600 YGFYTHVFRLKKWI 613
            G YT V     WI
Sbjct: 608 PGVYTKVAEYMDWI 621


>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
           precursor [Homo sapiens]
          Length = 699

 Score =  147 bits (371), Expect = 3e-35
 Identities = 89/265 (33%), Positives = 139/265 (52%), Gaps = 29/265 (10%)

Query: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCL--LYPPWDKNFTEN 420
           RI  G  A+ G +PW  ML   + Q   CG SL+   W++TAAHCL     P D    ++
Sbjct: 448 RIFNGRPAQKGTTPWIAMLSHLNGQPF-CGGSLLGSSWIVTAAHCLHQSLDPEDPTLRDS 506

Query: 421 DLL------VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAF 474
           DLL      + +GKH R R + N + + + +   +HP+Y+     + D+AL++L +    
Sbjct: 507 DLLSPSDFKIILGKHWRLRSDENEQHLGV-KHTTLHPQYD-PNTFENDVALVELLESPVL 564

Query: 475 SDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERP 534
           + ++ P+CLP+        Q G    V+GWG           +  P  L  + +PIV+  
Sbjct: 565 NAFVMPICLPEGPQ-----QEGAMVIVSGWGK-------QFLQRFPETLMEIEIPIVDHS 612

Query: 535 VCKDS---TRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 591
            C+ +    + ++T +M CAG K  EG + DAC GDSGGP V  +    +WY +G VSWG
Sbjct: 613 TCQKAYAPLKKKVTRDMICAGEK--EGGK-DACAGDSGGPMVTLNRERGQWYLVGTVSWG 669

Query: 592 EGCDRDGKYGFYTHVFRLKKWIQKV 616
           + C +  +YG Y+++   K WIQ+V
Sbjct: 670 DDCGKKDRYGVYSYIHHNKDWIQRV 694


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  147 bits (371), Expect = 3e-35
 Identities = 99/273 (36%), Positives = 139/273 (50%), Gaps = 48/273 (17%)

Query: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 422
           R+V G D + G  PWQV + R       CG SLI+++WVLTAAHC       +N +E  L
Sbjct: 34  RMVGGQDTQEGEWPWQVSIQRNGSH--FCGGSLIAEQWVLTAAHCF------RNTSETSL 85

Query: 423 ---------LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVA 473
                    LV+ G H+     R +E          +P Y    +   D+AL++L+ PV 
Sbjct: 86  YQVLLGARQLVQPGPHAMYARVRQVES---------NPLYQGTAS-SADVALVELEAPVP 135

Query: 474 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 533
           F++YI PVCLPD      + + G    VTGWG+  E         +P +LQ + +PI++ 
Sbjct: 136 FTNYILPVCLPDPSV---IFETGMNCWVTGWGSPSEEDLLP----EPRILQKLAVPIIDT 188

Query: 534 PVC-----KDST----RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQ 584
           P C     KD+        I ++M CAG+  +EGK+ DAC+GDSGGP V        W Q
Sbjct: 189 PKCNLLYSKDTEFGYQPKTIKNDMLCAGF--EEGKK-DACKGDSGGPLVCL--VGQSWLQ 243

Query: 585 MGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVI 617
            G++SWGEGC R  + G Y  V     WI ++I
Sbjct: 244 AGVISWGEGCARQNRPGVYIRVTAHHNWIHRII 276


>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
          Length = 352

 Score =  144 bits (362), Expect = 3e-34
 Identities = 91/289 (31%), Positives = 143/289 (49%), Gaps = 47/289 (16%)

Query: 334 ADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGA 393
           ++CG R +FE ++                RI  G +AE+G  PWQV +  +S  E  CG 
Sbjct: 51  SECGDRSIFEGRTRYS-------------RITGGMEAEVGEFPWQVSIQARS--EPFCGG 95

Query: 394 SLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRY 453
           S+++  W+LTAAHCL    + +     +L V +G +  T     I++++    I +H  +
Sbjct: 96  SILNKWWILTAAHCL----YSEELFPEELSVVLGTNDLTSPSMEIKEVA---SIILHKDF 148

Query: 454 NWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTA 513
             R N+D DIAL+ L  P+   D   P+CLP +   A+            W   +E W A
Sbjct: 149 K-RANMDNDIALLLLASPIKLDDLKVPICLPTQPGPAT------------W---RECWVA 192

Query: 514 NVGKGQPSVLQVVNLPIVERPVC----KDSTRI--RITDNMFCAGYKPDEGKRGDACEGD 567
             G+   +    V   +++ P+     ++ +++  ++T NM CAGYK +     DAC+GD
Sbjct: 193 GWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKNESY---DACKGD 249

Query: 568 SGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKV 616
           SGGP V       +WYQ+GI+SWG+ C      G YT +     WI+KV
Sbjct: 250 SGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKV 298


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  143 bits (360), Expect = 5e-34
 Identities = 102/274 (37%), Positives = 140/274 (51%), Gaps = 34/274 (12%)

Query: 360 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 419
           I  RIV G DAE+G  PWQ  L  +     +CG SL+S RW LTAAHC  +  +      
Sbjct: 38  ITSRIVGGEDAELGRWPWQGSL--RLWDSHVCGVSLLSHRWALTAAHC--FETYSDLSDP 93

Query: 420 NDLLVRIGKHSRTRYERNIEKIS---MLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSD 476
           +  +V+ G+ +      +++       +  IY+ PRY    N   DIAL+KL  PV ++ 
Sbjct: 94  SGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY--LGNSPYDIALVKLSAPVTYTK 151

Query: 477 YIHPVCLPDRETAASLLQAGYKGR----VTGWGNLKETWTANVGKGQPSVLQVVNLPIVE 532
           +I P+CL      AS  +  ++ R    VTGWG +KE    +     P  LQ V + I+ 
Sbjct: 152 HIQPICLQ-----ASTFE--FENRTDCWVTGWGYIKE----DEALPSPHTLQEVQVAIIN 200

Query: 533 RPVC-----KDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGI 587
             +C     K S R  I  +M CAG     GK  DAC GDSGGP       N  WYQ+G+
Sbjct: 201 NSMCNHLFLKYSFRKDIFGDMVCAG-NAQGGK--DACFGDSGGPLACNK--NGLWYQIGV 255

Query: 588 VSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG 621
           VSWG GC R  + G YT++    +WIQK++ Q G
Sbjct: 256 VSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSG 289


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  142 bits (358), Expect = 9e-34
 Identities = 107/278 (38%), Positives = 137/278 (49%), Gaps = 44/278 (15%)

Query: 360 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCL---LYPP--WD 414
           I  RIV G DAE+G  PWQ  L  +     +CG SL+S RW LTAAHC    L  P  W 
Sbjct: 38  ITSRIVGGEDAELGRWPWQGSL--RLWDSHVCGVSLLSHRWALTAAHCFETDLSDPSGWM 95

Query: 415 KNFTENDLLVRIGKHSR--TRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPV 472
             F +   +          TRY         +  IY+ PRY    N   DIAL+KL  PV
Sbjct: 96  VQFGQLTSMPSFWSLQAYYTRY--------FVSNIYLSPRY--LGNSPYDIALVKLSAPV 145

Query: 473 AFSDYIHPVCLPDRETAASLLQAGYKGR----VTGWGNLKETWTANVGKGQPSVLQVVNL 528
            ++ +I P+CL      AS  +  ++ R    VTGWG +KE    +     P  LQ V +
Sbjct: 146 TYTKHIQPICLQ-----ASTFE--FENRTDCWVTGWGYIKE----DEALPSPHTLQEVQV 194

Query: 529 PIVERPVC-----KDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWY 583
            I+   +C     K S R  I  +M CAG     GK  DAC GDSGGP       N  WY
Sbjct: 195 AIINNSMCNHLFLKYSFRKDIFGDMVCAG-NAQGGK--DACFGDSGGPLACNK--NGLWY 249

Query: 584 QMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG 621
           Q+G+VSWG GC R  + G YT++    +WIQK++ Q G
Sbjct: 250 QIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSG 287


>gi|66347875 complement component 1, r subcomponent [Homo sapiens]
          Length = 705

 Score =  141 bits (356), Expect = 2e-33
 Identities = 94/269 (34%), Positives = 137/269 (50%), Gaps = 40/269 (14%)

Query: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 422
           RI+ G  A++G  PWQV            G +L+ DRW+LTAAH L YP   +  +   L
Sbjct: 463 RIIGGQKAKMGNFPWQVFTNIHGRG----GGALLGDRWILTAAHTL-YPKEHEAQSNASL 517

Query: 423 LVRIGKHSRTRYERNIEKISML-----EKIYIHPRYNWRE--NLDRDIALMKLKKPVAFS 475
            V +G         N+E++  L      ++ +HP Y   E  N + DIAL++L+  V   
Sbjct: 518 DVFLG-------HTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLG 570

Query: 476 DYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPV 535
             + P+CLPD +T   L   G  G V+G+G ++E    +        L+ V LP+     
Sbjct: 571 PNLLPICLPDNDTFYDL---GLMGYVSGFGVMEEKIAHD--------LRFVRLPVANPQA 619

Query: 536 CKDSTRIR-----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSW 590
           C++  R +      + NMFCAG+      + DAC+GDSGG F ++ P  +RW   GIVSW
Sbjct: 620 CENWLRGKNRMDVFSQNMFCAGHP---SLKQDACQGDSGGVFAVRDPNTDRWVATGIVSW 676

Query: 591 GEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 619
           G GC R   YGFYT V     WI+K +++
Sbjct: 677 GIGCSRG--YGFYTKVLNYVDWIKKEMEE 703


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  140 bits (354), Expect = 3e-33
 Identities = 106/271 (39%), Positives = 133/271 (49%), Gaps = 34/271 (12%)

Query: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 422
           RIV G D  +G  PWQV L        LCG SL+S  WVLTAAHC  +P        N +
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGAH--LCGGSLLSGDWVLTAAHC--FPE------RNRV 211

Query: 423 LVRIGKHSRTRYERNIEKISM-LEKIYIHPRY------NWRENLDRDIALMKLKKPVAFS 475
           L R    +    + +   + + ++ +  H  Y      N  EN   DIAL+ L  P+  +
Sbjct: 212 LSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN-SNDIALVHLSSPLPLT 270

Query: 476 DYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPV 535
           +YI PVCLP    A   L  G    VTGWGN     T   G+ Q  VLQ   +PI+   V
Sbjct: 271 EYIQPVCLP---AAGQALVDGKICTVTGWGN-----TQYYGQ-QAGVLQEARVPIISNDV 321

Query: 536 CK--DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNN--RWYQMGIVSWG 591
           C   D    +I   MFCAGY P+ G   DAC+GDSGGPFV +   +   RW   GIVSWG
Sbjct: 322 CNGADFYGNQIKPKMFCAGY-PEGGI--DACQGDSGGPFVCEDSISRTPRWRLCGIVSWG 378

Query: 592 EGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 622
            GC    K G YT V   ++WI + I    E
Sbjct: 379 TGCALAQKPGVYTKVSDFREWIFQAIKTHSE 409


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  140 bits (354), Expect = 3e-33
 Identities = 106/271 (39%), Positives = 133/271 (49%), Gaps = 34/271 (12%)

Query: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 422
           RIV G D  +G  PWQV L        LCG SL+S  WVLTAAHC  +P        N +
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGAH--LCGGSLLSGDWVLTAAHC--FPE------RNRV 211

Query: 423 LVRIGKHSRTRYERNIEKISM-LEKIYIHPRY------NWRENLDRDIALMKLKKPVAFS 475
           L R    +    + +   + + ++ +  H  Y      N  EN   DIAL+ L  P+  +
Sbjct: 212 LSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN-SNDIALVHLSSPLPLT 270

Query: 476 DYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPV 535
           +YI PVCLP    A   L  G    VTGWGN     T   G+ Q  VLQ   +PI+   V
Sbjct: 271 EYIQPVCLP---AAGQALVDGKICTVTGWGN-----TQYYGQ-QAGVLQEARVPIISNDV 321

Query: 536 CK--DSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNN--RWYQMGIVSWG 591
           C   D    +I   MFCAGY P+ G   DAC+GDSGGPFV +   +   RW   GIVSWG
Sbjct: 322 CNGADFYGNQIKPKMFCAGY-PEGGI--DACQGDSGGPFVCEDSISRTPRWRLCGIVSWG 378

Query: 592 EGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 622
            GC    K G YT V   ++WI + I    E
Sbjct: 379 TGCALAQKPGVYTKVSDFREWIFQAIKTHSE 409


>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
           sapiens]
          Length = 560

 Score =  140 bits (352), Expect = 5e-33
 Identities = 139/489 (28%), Positives = 197/489 (40%), Gaps = 100/489 (20%)

Query: 157 CRNPDSSTTGPWCYTTDPTVRRQECSI-PVCGQ----DQVTVAMTPRSEGSSVNLSPPLE 211
           C++P    TGP C    P  R   C     C +     + T A   + +G    +    +
Sbjct: 138 CKHP---YTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGS--D 192

Query: 212 QCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVE-------NFCRN 264
            C    G  Y+G++  T +   CL W S     L   +++N  ++  E       NFCRN
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSH----LLLQENYNMFMEDAETHGIGEHNFCRN 248

Query: 265 PDGDEEGVWCY--VAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQT 322
           PD DE+  WC+  V      + YCD++ C                D A    + T     
Sbjct: 249 PDADEKP-WCFIKVTNDKVKWEYCDVSACSA-------------QDVAYPEESPTE---- 290

Query: 323 FFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLF 382
              P T   G   CG   + E+K                 RI  G  +  G  PWQ  L 
Sbjct: 291 ---PSTKLPGFDSCGKTEIAERKIK---------------RIYGGFKSTAGKHPWQASLQ 332

Query: 383 RK------SPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYER 436
                    PQ   CG +LI   WVLTAAHC        +     L V +G     + E 
Sbjct: 333 SSLPLTISMPQGHFCGGALIHPCWVLTAAHC-------TDIKTRHLKVVLGDQDLKKEEF 385

Query: 437 NIEKISMLEKIYIHPRYNWRENL-DRDIALMKLKKPV-----AFSDYIHPVCLPDRETAA 490
           + E+   +EKI+ +  YN R+ +   DIAL+KL KPV       S Y+  VCLPD     
Sbjct: 386 H-EQSFRVEKIFKYSHYNERDEIPHNDIALLKL-KPVDGHCALESKYVKTVCLPD----- 438

Query: 491 SLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI--RITDNM 548
               +G +  ++GWG          GKG   +L    + ++   +C         I D+M
Sbjct: 439 GSFPSGSECHISGWG------VTETGKGSRQLLD-AKVKLIANTLCNSRQLYDHMIDDSM 491

Query: 549 FCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFR 608
            CAG     G+  D C+GDSGGP   +   +  +Y  GIVSWG  C +  + G YT V +
Sbjct: 492 ICAGNLQKPGQ--DTCQGDSGGPLTCEK--DGTYYVYGIVSWGLECGK--RPGVYTQVTK 545

Query: 609 LKKWIQKVI 617
              WI+  I
Sbjct: 546 FLNWIKATI 554



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 10/104 (9%)

Query: 107 NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEIN-----STTHPGADLQENFCRNPD 161
           +C  G G +YRG +N T +   C  W S    +   N     + TH     + NFCRNPD
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIG--EHNFCRNPD 250

Query: 162 SSTTGPWCY--TTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSS 203
           +    PWC+   T+  V+ + C +  C    V       +E S+
Sbjct: 251 ADEK-PWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPST 293


>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
          Length = 416

 Score =  139 bits (351), Expect = 6e-33
 Identities = 97/264 (36%), Positives = 131/264 (49%), Gaps = 29/264 (10%)

Query: 353 RELLESYIDG-RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYP 411
           R++  S I G +IV G  +  G  PWQ  +  K      CGASLIS RW+L+AAHC    
Sbjct: 173 RQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRH--YCGASLISSRWLLSAAHCFAKK 230

Query: 412 PWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKP 471
              K++T N  +V + K   TR  +NI           H  Y+    L  DIAL++L + 
Sbjct: 231 NNSKDWTVNFGIV-VNKPYMTRKVQNI---------IFHENYS-SPGLHDDIALVQLAEE 279

Query: 472 VAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIV 531
           V+F++YI  +CLP+   A   L       VTGWG L       +    P +LQ   L I+
Sbjct: 280 VSFTEYIRKICLPE---AKMKLSENDNVVVTGWGTLY------MNGSFPVILQEDFLKII 330

Query: 532 ERPVCKDSTRIR--ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 589
           +  +C  S      +TD M CAG+   E    DAC+ DSGGP        N W+ +GIVS
Sbjct: 331 DNKICNASYAYSGFVTDTMLCAGFMSGEA---DACQNDSGGPLAYPDS-RNIWHLVGIVS 386

Query: 590 WGEGCDRDGKYGFYTHVFRLKKWI 613
           WG+GC +  K G YT V   + WI
Sbjct: 387 WGDGCGKKNKPGVYTRVTSYRNWI 410


>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  139 bits (349), Expect = 1e-32
 Identities = 92/257 (35%), Positives = 131/257 (50%), Gaps = 34/257 (13%)

Query: 361 DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 420
           D +IV G   E    P+QV L   +     CG SLIS++WV++A HC           ++
Sbjct: 21  DDKIVGGYICEENSVPYQVSL---NSGYHFCGGSLISEQWVVSAGHCY----------KS 67

Query: 421 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 480
            + VR+G+H+    E N E+     KI  HP+YN R  LD DI L+KL  P   +  +  
Sbjct: 68  RIQVRLGEHNIEVLEGN-EQFINAAKIIRHPKYNSR-TLDNDILLIKLSSPAVINSRVSA 125

Query: 481 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 540
           + LP    AA     G +  ++GWGN     T + G   P  LQ ++ P++ +  C+ S 
Sbjct: 126 ISLPTAPPAA-----GTESLISGWGN-----TLSSGADYPDELQCLDAPVLSQAECEASY 175

Query: 541 RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY 600
             +IT+NMFC G+   EG + D+C+GDSGGP V            GIVSWG GC +  + 
Sbjct: 176 PGKITNNMFCVGFL--EGGK-DSCQGDSGGPVVSNGELQ------GIVSWGYGCAQKNRP 226

Query: 601 GFYTHVFRLKKWIQKVI 617
           G YT V+    WI+  I
Sbjct: 227 GVYTKVYNYVDWIKDTI 243


>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
          Length = 247

 Score =  137 bits (346), Expect = 2e-32
 Identities = 90/257 (35%), Positives = 133/257 (51%), Gaps = 34/257 (13%)

Query: 361 DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 420
           D +IV G + E    P+QV L   +     CG SLI+++WV++A HC           ++
Sbjct: 21  DDKIVGGYNCEENSVPYQVSL---NSGYHFCGGSLINEQWVVSAGHCY----------KS 67

Query: 421 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 480
            + VR+G+H+    E N E+     KI  HP+Y+ R+ L+ DI L+KL      +  +  
Sbjct: 68  RIQVRLGEHNIEVLEGN-EQFINAAKIIRHPQYD-RKTLNNDIMLIKLSSRAVINARVST 125

Query: 481 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 540
           + LP    A      G K  ++GWGN     TA+ G   P  LQ ++ P++ +  C+ S 
Sbjct: 126 ISLPTAPPAT-----GTKCLISGWGN-----TASSGADYPDELQCLDAPVLSQAKCEASY 175

Query: 541 RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY 600
             +IT NMFC G+   EG + D+C+GDSGGP V            G+VSWG+GC +  K 
Sbjct: 176 PGKITSNMFCVGFL--EGGK-DSCQGDSGGPVVCNGQLQ------GVVSWGDGCAQKNKP 226

Query: 601 GFYTHVFRLKKWIQKVI 617
           G YT V+   KWI+  I
Sbjct: 227 GVYTKVYNYVKWIKNTI 243


>gi|4503137 chymotrypsin-like [Homo sapiens]
          Length = 264

 Score =  136 bits (342), Expect = 7e-32
 Identities = 93/255 (36%), Positives = 124/255 (48%), Gaps = 26/255 (10%)

Query: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 422
           RIV G +A +G  PWQV L + S     CG SLIS  WV+TAAHC        N +    
Sbjct: 33  RIVNGENAVLGSWPWQVSL-QDSSGFHFCGGSLISQSWVVTAAHC--------NVSPGRH 83

Query: 423 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 482
            V +G++ R+     ++ +S+   I  HP +N    ++ D+ L+KL  P  ++  I PVC
Sbjct: 84  FVVLGEYDRSSNAEPLQVLSVSRAI-THPSWN-STTMNNDVTLLKLASPAQYTTRISPVC 141

Query: 483 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 542
           L     A   L  G     TGWG L     + VG   P+ LQ V LP+V    C+     
Sbjct: 142 LASSNEA---LTEGLTCVTTGWGRL-----SGVGNVTPAHLQQVALPLVTVNQCRQYWGS 193

Query: 543 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGF 602
            ITD+M CAG     G    +C+GDSGGP V +    N W  +GIVSWG           
Sbjct: 194 SITDSMICAG-----GAGASSCQGDSGGPLVCQK--GNTWVLIGIVSWGTKNCNVRAPAV 246

Query: 603 YTHVFRLKKWIQKVI 617
           YT V +   WI +VI
Sbjct: 247 YTRVSKFSTWINQVI 261


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,564,293
Number of Sequences: 37866
Number of extensions: 1265592
Number of successful extensions: 3553
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 2601
Number of HSP's gapped (non-prelim): 287
length of query: 622
length of database: 18,247,518
effective HSP length: 108
effective length of query: 514
effective length of database: 14,157,990
effective search space: 7277206860
effective search space used: 7277206860
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.