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Search of human proteins with 4503431
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503431 dysferlin isoform 8 [Homo sapiens]
(2080 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503431 dysferlin isoform 8 [Homo sapiens] 4284 0.0
gi|195976758 dysferlin isoform 11 [Homo sapiens] 4272 0.0
gi|195976760 dysferlin isoform 12 [Homo sapiens] 4268 0.0
gi|195976754 dysferlin isoform 9 [Homo sapiens] 4247 0.0
gi|195976756 dysferlin isoform 10 [Homo sapiens] 4234 0.0
gi|195976821 dysferlin isoform 2 [Homo sapiens] 4234 0.0
gi|195976762 dysferlin isoform 13 [Homo sapiens] 4231 0.0
gi|195976769 dysferlin isoform 6 [Homo sapiens] 4222 0.0
gi|195976764 dysferlin isoform 14 [Homo sapiens] 4218 0.0
gi|195976766 dysferlin isoform 7 [Homo sapiens] 4218 0.0
gi|195976777 dysferlin isoform 3 [Homo sapiens] 4196 0.0
gi|195976773 dysferlin isoform 5 [Homo sapiens] 4184 0.0
gi|195976775 dysferlin isoform 4 [Homo sapiens] 4180 0.0
gi|195976779 dysferlin isoform 1 [Homo sapiens] 4168 0.0
gi|7305053 myoferlin isoform a [Homo sapiens] 2379 0.0
gi|19718759 myoferlin isoform b [Homo sapiens] 2377 0.0
gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens] 1436 0.0
gi|35493868 otoferlin isoform b [Homo sapiens] 720 0.0
gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens] 714 0.0
gi|35493853 otoferlin isoform c [Homo sapiens] 712 0.0
gi|35493860 otoferlin isoform d [Homo sapiens] 712 0.0
gi|34740331 otoferlin isoform a [Homo sapiens] 712 0.0
gi|119120884 fer-1-like 6 [Homo sapiens] 709 0.0
gi|4759026 RAS protein activator like 1 [Homo sapiens] 65 5e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 54 1e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 54 1e-06
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 54 2e-06
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 54 2e-06
gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva... 53 3e-06
gi|239743307 PREDICTED: similar to calcium-promoted Ras inactiva... 53 3e-06
>gi|4503431 dysferlin isoform 8 [Homo sapiens]
Length = 2080
Score = 4284 bits (11112), Expect = 0.0
Identities = 2080/2080 (100%), Positives = 2080/2080 (100%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
Query: 181 GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV
Sbjct: 181 GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
Query: 241 VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE
Sbjct: 241 VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
Query: 301 FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED
Sbjct: 301 FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
Query: 361 KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV
Sbjct: 361 KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
Query: 421 EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL
Sbjct: 421 EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
Query: 481 SMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 540
SMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT
Sbjct: 481 SMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 540
Query: 541 ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 600
ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS
Sbjct: 541 ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 600
Query: 601 ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 660
ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV
Sbjct: 601 ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 660
Query: 661 LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 720
LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC
Sbjct: 661 LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 720
Query: 721 SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 780
SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR
Sbjct: 721 SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 780
Query: 781 ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 840
ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM
Sbjct: 781 ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 840
Query: 841 EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 900
EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT
Sbjct: 841 EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 900
Query: 901 YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 960
YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL
Sbjct: 901 YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 960
Query: 961 PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1020
PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP
Sbjct: 961 PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1020
Query: 1021 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1080
ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH
Sbjct: 1021 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1080
Query: 1081 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1140
LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP
Sbjct: 1081 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1140
Query: 1141 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1200
TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD
Sbjct: 1141 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1200
Query: 1201 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1260
QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL
Sbjct: 1201 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1260
Query: 1261 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1320
TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM
Sbjct: 1261 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1320
Query: 1321 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1380
VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF
Sbjct: 1321 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1380
Query: 1381 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1440
DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP
Sbjct: 1381 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1440
Query: 1441 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFD 1500
QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFD
Sbjct: 1441 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFD 1500
Query: 1501 TLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAI 1560
TLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAI
Sbjct: 1501 TLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAI 1560
Query: 1561 PMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIP 1620
PMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIP
Sbjct: 1561 PMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIP 1620
Query: 1621 CTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGL 1680
CTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGL
Sbjct: 1621 CTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGL 1680
Query: 1681 PQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPN 1740
PQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPN
Sbjct: 1681 PQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPN 1740
Query: 1741 PHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPP 1800
PHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPP
Sbjct: 1741 PHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPP 1800
Query: 1801 FNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1860
FNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS
Sbjct: 1801 FNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1860
Query: 1861 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1920
LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD
Sbjct: 1861 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1920
Query: 1921 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKI 1980
FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKI
Sbjct: 1921 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKI 1980
Query: 1981 LAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILW 2040
LAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILW
Sbjct: 1981 LAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILW 2040
Query: 2041 RRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2080
RRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2041 RRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2080
>gi|195976758 dysferlin isoform 11 [Homo sapiens]
Length = 2101
Score = 4272 bits (11080), Expect = 0.0
Identities = 2080/2101 (99%), Positives = 2080/2101 (99%), Gaps = 21/2101 (0%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
Query: 181 GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV
Sbjct: 181 GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
Query: 241 VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE
Sbjct: 241 VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
Query: 301 FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED
Sbjct: 301 FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
Query: 361 KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV
Sbjct: 361 KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
Query: 421 EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL
Sbjct: 421 EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
Query: 481 SMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 540
SMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT
Sbjct: 481 SMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 540
Query: 541 ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 600
ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS
Sbjct: 541 ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 600
Query: 601 ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 660
ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV
Sbjct: 601 ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 660
Query: 661 LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 720
LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC
Sbjct: 661 LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 720
Query: 721 SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 780
SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR
Sbjct: 721 SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 780
Query: 781 ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 840
ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM
Sbjct: 781 ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 840
Query: 841 EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 900
EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT
Sbjct: 841 EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 900
Query: 901 YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 960
YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL
Sbjct: 901 YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 960
Query: 961 PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1020
PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP
Sbjct: 961 PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1020
Query: 1021 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1080
ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH
Sbjct: 1021 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1080
Query: 1081 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1140
LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP
Sbjct: 1081 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1140
Query: 1141 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1200
TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD
Sbjct: 1141 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1200
Query: 1201 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1260
QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL
Sbjct: 1201 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1260
Query: 1261 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1320
TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM
Sbjct: 1261 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1320
Query: 1321 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1380
VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF
Sbjct: 1321 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1380
Query: 1381 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1440
DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP
Sbjct: 1381 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1440
Query: 1441 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWWS 1479
QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ EEEFIDWWS
Sbjct: 1441 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWS 1500
Query: 1480 KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP 1539
KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP
Sbjct: 1501 KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP 1560
Query: 1540 SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC 1599
SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC
Sbjct: 1561 SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC 1620
Query: 1600 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1659
DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI
Sbjct: 1621 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1680
Query: 1660 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD 1719
GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD
Sbjct: 1681 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD 1740
Query: 1720 RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE 1779
RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE
Sbjct: 1741 RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE 1800
Query: 1780 QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY 1839
QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY
Sbjct: 1801 QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY 1860
Query: 1840 VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE 1899
VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE
Sbjct: 1861 VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE 1920
Query: 1900 SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL 1959
SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL
Sbjct: 1921 SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL 1980
Query: 1960 FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2019
FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR
Sbjct: 1981 FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2040
Query: 2020 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF 2079
RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF
Sbjct: 2041 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF 2100
Query: 2080 S 2080
S
Sbjct: 2101 S 2101
>gi|195976760 dysferlin isoform 12 [Homo sapiens]
Length = 2111
Score = 4268 bits (11070), Expect = 0.0
Identities = 2080/2111 (98%), Positives = 2080/2111 (98%), Gaps = 31/2111 (1%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA---------------------------- 152
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
Query: 153 ---DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 209
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
Query: 210 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 269
RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
Query: 270 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 329
LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
Query: 330 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 389
SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
Query: 390 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 449
DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
Query: 450 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLD 509
AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLD
Sbjct: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLD 540
Query: 510 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 569
DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE
Sbjct: 541 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 600
Query: 570 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 629
QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL
Sbjct: 601 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 660
Query: 630 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 689
PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL
Sbjct: 661 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 720
Query: 690 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 749
EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS
Sbjct: 721 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 780
Query: 750 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 809
QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV
Sbjct: 781 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 840
Query: 810 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 869
PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ
Sbjct: 841 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 900
Query: 870 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 929
FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD
Sbjct: 901 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 960
Query: 930 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 989
WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP
Sbjct: 961 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 1020
Query: 990 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1049
LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD
Sbjct: 1021 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1080
Query: 1050 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1109
LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV
Sbjct: 1081 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1140
Query: 1110 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1169
FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK
Sbjct: 1141 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1200
Query: 1170 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1229
DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY
Sbjct: 1201 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1260
Query: 1230 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1289
DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG
Sbjct: 1261 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1320
Query: 1290 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1349
FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL
Sbjct: 1321 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1380
Query: 1350 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1409
ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR
Sbjct: 1381 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1440
Query: 1410 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1469
QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI
Sbjct: 1441 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1500
Query: 1470 QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR 1529
QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR
Sbjct: 1501 QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR 1560
Query: 1530 GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG 1589
GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG
Sbjct: 1561 GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG 1620
Query: 1590 LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD 1649
LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD
Sbjct: 1621 LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD 1680
Query: 1650 YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH 1709
YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH
Sbjct: 1681 YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH 1740
Query: 1710 RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP 1769
RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP
Sbjct: 1741 RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP 1800
Query: 1770 LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS 1829
LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS
Sbjct: 1801 LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS 1860
Query: 1830 LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK 1889
LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK
Sbjct: 1861 LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK 1920
Query: 1890 DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD 1949
DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD
Sbjct: 1921 DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD 1980
Query: 1950 AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP 2009
AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP
Sbjct: 1981 AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP 2040
Query: 2010 NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN 2069
NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN
Sbjct: 2041 NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN 2100
Query: 2070 YAAMKLVKPFS 2080
YAAMKLVKPFS
Sbjct: 2101 YAAMKLVKPFS 2111
>gi|195976754 dysferlin isoform 9 [Homo sapiens]
Length = 2066
Score = 4247 bits (11014), Expect = 0.0
Identities = 2065/2080 (99%), Positives = 2066/2080 (99%), Gaps = 14/2080 (0%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
Query: 181 GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV
Sbjct: 181 GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
Query: 241 VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE
Sbjct: 241 VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
Query: 301 FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED
Sbjct: 301 FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
Query: 361 KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV
Sbjct: 361 KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
Query: 421 EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL
Sbjct: 421 EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
Query: 481 SMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 540
SMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPYT
Sbjct: 481 SMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 526
Query: 541 ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 600
ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS
Sbjct: 527 ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 586
Query: 601 ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 660
ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV
Sbjct: 587 ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 646
Query: 661 LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 720
LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC
Sbjct: 647 LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 706
Query: 721 SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 780
SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR
Sbjct: 707 SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 766
Query: 781 ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 840
ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM
Sbjct: 767 ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 826
Query: 841 EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 900
EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT
Sbjct: 827 EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 886
Query: 901 YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 960
YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL
Sbjct: 887 YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 946
Query: 961 PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1020
PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP
Sbjct: 947 PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1006
Query: 1021 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1080
ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH
Sbjct: 1007 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1066
Query: 1081 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1140
LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP
Sbjct: 1067 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1126
Query: 1141 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1200
TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD
Sbjct: 1127 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1186
Query: 1201 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1260
QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL
Sbjct: 1187 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1246
Query: 1261 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1320
TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM
Sbjct: 1247 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1306
Query: 1321 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1380
VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF
Sbjct: 1307 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1366
Query: 1381 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1440
DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP
Sbjct: 1367 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1426
Query: 1441 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFD 1500
QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFD
Sbjct: 1427 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFD 1486
Query: 1501 TLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAI 1560
TLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAI
Sbjct: 1487 TLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAI 1546
Query: 1561 PMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIP 1620
PMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIP
Sbjct: 1547 PMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIP 1606
Query: 1621 CTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGL 1680
CTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGL
Sbjct: 1607 CTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGL 1666
Query: 1681 PQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPN 1740
PQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPN
Sbjct: 1667 PQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPN 1726
Query: 1741 PHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPP 1800
PHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPP
Sbjct: 1727 PHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPP 1786
Query: 1801 FNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1860
FNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS
Sbjct: 1787 FNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1846
Query: 1861 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1920
LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD
Sbjct: 1847 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1906
Query: 1921 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKI 1980
FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKI
Sbjct: 1907 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKI 1966
Query: 1981 LAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILW 2040
LAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILW
Sbjct: 1967 LAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILW 2026
Query: 2041 RRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2080
RRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2027 RRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2066
>gi|195976756 dysferlin isoform 10 [Homo sapiens]
Length = 2087
Score = 4234 bits (10982), Expect = 0.0
Identities = 2065/2101 (98%), Positives = 2066/2101 (98%), Gaps = 35/2101 (1%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGGP 180
Query: 181 GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV
Sbjct: 181 GAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPV 240
Query: 241 VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE
Sbjct: 241 VKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLGE 300
Query: 301 FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED
Sbjct: 301 FRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSED 360
Query: 361 KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV
Sbjct: 361 KEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPFV 420
Query: 421 EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL
Sbjct: 421 EVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTYL 480
Query: 481 SMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 540
SMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPYT
Sbjct: 481 SMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPYT 526
Query: 541 ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 600
ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS
Sbjct: 527 ELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFYS 586
Query: 601 ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 660
ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV
Sbjct: 587 ATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVVV 646
Query: 661 LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 720
LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC
Sbjct: 647 LSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGC 706
Query: 721 SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 780
SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR
Sbjct: 707 SQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRLR 766
Query: 781 ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 840
ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM
Sbjct: 767 ALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPM 826
Query: 841 EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 900
EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT
Sbjct: 827 EKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGLT 886
Query: 901 YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 960
YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL
Sbjct: 887 YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTRL 946
Query: 961 PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1020
PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP
Sbjct: 947 PGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIPP 1006
Query: 1021 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1080
ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH
Sbjct: 1007 ERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKFH 1066
Query: 1081 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1140
LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP
Sbjct: 1067 LEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNRP 1126
Query: 1141 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1200
TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD
Sbjct: 1127 TISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWD 1186
Query: 1201 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1260
QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL
Sbjct: 1187 QTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFPL 1246
Query: 1261 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1320
TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM
Sbjct: 1247 TRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIYM 1306
Query: 1321 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1380
VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF
Sbjct: 1307 VPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPNF 1366
Query: 1381 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1440
DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP
Sbjct: 1367 DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPSP 1426
Query: 1441 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWWS 1479
QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ EEEFIDWWS
Sbjct: 1427 QGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWWS 1486
Query: 1480 KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP 1539
KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP
Sbjct: 1487 KFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDP 1546
Query: 1540 SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC 1599
SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC
Sbjct: 1547 SVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKC 1606
Query: 1600 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1659
DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI
Sbjct: 1607 DPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKI 1666
Query: 1660 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD 1719
GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD
Sbjct: 1667 GETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD 1726
Query: 1720 RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE 1779
RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE
Sbjct: 1727 RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIE 1786
Query: 1780 QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY 1839
QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY
Sbjct: 1787 QGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIY 1846
Query: 1840 VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE 1899
VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE
Sbjct: 1847 VKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTE 1906
Query: 1900 SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL 1959
SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL
Sbjct: 1907 SKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSL 1966
Query: 1960 FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2019
FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR
Sbjct: 1967 FEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2026
Query: 2020 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF 2079
RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF
Sbjct: 2027 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPF 2086
Query: 2080 S 2080
S
Sbjct: 2087 S 2087
>gi|195976821 dysferlin isoform 2 [Homo sapiens]
Length = 2081
Score = 4234 bits (10981), Expect = 0.0
Identities = 2060/2081 (98%), Positives = 2064/2081 (99%), Gaps = 1/2081 (0%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
Query: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
Query: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
Query: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
Query: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
Query: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
Query: 480 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539
LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
Query: 540 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
Query: 600 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
Query: 660 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 719
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
Query: 720 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 779
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
Query: 780 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 839
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
Query: 840 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 899
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
Query: 900 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 959
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
Query: 960 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1019
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
Query: 1020 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1079
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
Query: 1080 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1139
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
Query: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
Query: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1259
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
Query: 1260 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1319
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
Query: 1320 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1379
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
Query: 1380 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1439
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
Query: 1440 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDF 1499
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDF
Sbjct: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDF 1500
Query: 1500 DTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPA 1559
DTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPA
Sbjct: 1501 DTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPA 1560
Query: 1560 IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYI 1619
IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYI
Sbjct: 1561 IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYI 1620
Query: 1620 PCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCG 1679
PCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCG
Sbjct: 1621 PCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCG 1680
Query: 1680 LPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIP 1739
LPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIP
Sbjct: 1681 LPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIP 1740
Query: 1740 NPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGP 1799
NPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGP
Sbjct: 1741 NPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGP 1800
Query: 1800 PFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYR 1859
PFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYR
Sbjct: 1801 PFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYR 1860
Query: 1860 SLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFD 1919
SLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFD
Sbjct: 1861 SLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFD 1920
Query: 1920 DFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKK 1979
DFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKK
Sbjct: 1921 DFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKK 1980
Query: 1980 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2039
ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL
Sbjct: 1981 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2040
Query: 2040 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2080
WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2041 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2081
>gi|195976762 dysferlin isoform 13 [Homo sapiens]
Length = 2097
Score = 4231 bits (10972), Expect = 0.0
Identities = 2065/2111 (97%), Positives = 2066/2111 (97%), Gaps = 45/2111 (2%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA---------------------------- 152
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
Query: 153 ---DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 209
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
Query: 210 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 269
RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
Query: 270 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 329
LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
Query: 330 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 389
SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
Query: 390 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 449
DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
Query: 450 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLD 509
AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +D
Sbjct: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------VD 526
Query: 510 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 569
DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE
Sbjct: 527 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 586
Query: 570 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 629
QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL
Sbjct: 587 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 646
Query: 630 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 689
PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL
Sbjct: 647 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 706
Query: 690 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 749
EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS
Sbjct: 707 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 766
Query: 750 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 809
QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV
Sbjct: 767 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 826
Query: 810 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 869
PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ
Sbjct: 827 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 886
Query: 870 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 929
FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD
Sbjct: 887 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 946
Query: 930 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 989
WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP
Sbjct: 947 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 1006
Query: 990 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1049
LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD
Sbjct: 1007 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1066
Query: 1050 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1109
LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV
Sbjct: 1067 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1126
Query: 1110 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1169
FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK
Sbjct: 1127 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1186
Query: 1170 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1229
DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY
Sbjct: 1187 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1246
Query: 1230 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1289
DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG
Sbjct: 1247 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1306
Query: 1290 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1349
FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL
Sbjct: 1307 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1366
Query: 1350 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1409
ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR
Sbjct: 1367 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1426
Query: 1410 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1469
QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI
Sbjct: 1427 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1486
Query: 1470 QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR 1529
QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR
Sbjct: 1487 QEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYR 1546
Query: 1530 GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG 1589
GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG
Sbjct: 1547 GKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFG 1606
Query: 1590 LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD 1649
LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD
Sbjct: 1607 LQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYD 1666
Query: 1650 YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH 1709
YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH
Sbjct: 1667 YDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQH 1726
Query: 1710 RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP 1769
RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP
Sbjct: 1727 RVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRP 1786
Query: 1770 LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS 1829
LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS
Sbjct: 1787 LYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLS 1846
Query: 1830 LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK 1889
LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK
Sbjct: 1847 LTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKK 1906
Query: 1890 DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD 1949
DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD
Sbjct: 1907 DAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD 1966
Query: 1950 AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP 2009
AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP
Sbjct: 1967 AFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEP 2026
Query: 2010 NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN 2069
NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN
Sbjct: 2027 NMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPN 2086
Query: 2070 YAAMKLVKPFS 2080
YAAMKLVKPFS
Sbjct: 2087 YAAMKLVKPFS 2097
>gi|195976769 dysferlin isoform 6 [Homo sapiens]
Length = 2102
Score = 4222 bits (10949), Expect = 0.0
Identities = 2060/2102 (98%), Positives = 2064/2102 (98%), Gaps = 22/2102 (1%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
Query: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
Query: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
Query: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
Query: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
Query: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
Query: 480 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539
LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 481 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 540
Query: 540 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 541 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 600
Query: 600 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 601 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 660
Query: 660 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 719
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 661 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 720
Query: 720 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 779
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 721 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 780
Query: 780 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 839
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 781 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 840
Query: 840 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 899
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 841 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 900
Query: 900 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 959
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 901 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 960
Query: 960 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1019
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 961 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1020
Query: 1020 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1079
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1021 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1080
Query: 1080 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1139
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1081 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1140
Query: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1141 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1200
Query: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1259
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1201 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1260
Query: 1260 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1319
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1261 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1320
Query: 1320 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1379
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1321 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1380
Query: 1380 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1439
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1381 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1440
Query: 1440 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWW 1478
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ EEEFIDWW
Sbjct: 1441 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1500
Query: 1479 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1538
SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1501 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1560
Query: 1539 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1598
PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1561 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1620
Query: 1599 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1658
CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1621 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1680
Query: 1659 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1718
IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1681 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1740
Query: 1719 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1778
DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1741 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1800
Query: 1779 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1838
EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1801 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1860
Query: 1839 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1898
YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1861 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1920
Query: 1899 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1958
ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1921 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1980
Query: 1959 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2018
LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1981 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2040
Query: 2019 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2078
RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2041 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
Query: 2079 FS 2080
FS
Sbjct: 2101 FS 2102
>gi|195976764 dysferlin isoform 14 [Homo sapiens]
Length = 2118
Score = 4218 bits (10940), Expect = 0.0
Identities = 2065/2132 (96%), Positives = 2066/2132 (96%), Gaps = 66/2132 (3%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD
Sbjct: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ
Sbjct: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQ 120
Query: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA---------------------------- 152
VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 VSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKWP 180
Query: 153 ---DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 209
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS
Sbjct: 181 APTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTS 240
Query: 210 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 269
RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN
Sbjct: 241 RKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFFN 300
Query: 270 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 329
LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF
Sbjct: 301 LFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDF 360
Query: 330 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 389
SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE
Sbjct: 361 SAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAE 420
Query: 390 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 449
DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP
Sbjct: 421 DLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLP 480
Query: 450 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLD 509
AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +D
Sbjct: 481 AMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------VD 526
Query: 510 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 569
DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE
Sbjct: 527 DYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSE 586
Query: 570 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 629
QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL
Sbjct: 587 QKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCL 646
Query: 630 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 689
PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL
Sbjct: 647 PLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGL 706
Query: 690 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 749
EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS
Sbjct: 707 EQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHLS 766
Query: 750 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 809
QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV
Sbjct: 767 QITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRV 826
Query: 810 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 869
PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ
Sbjct: 827 PAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQ 886
Query: 870 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 929
FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD
Sbjct: 887 FAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAGD 946
Query: 930 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 989
WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP
Sbjct: 947 WFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECP 1006
Query: 990 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1049
LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD
Sbjct: 1007 LGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRD 1066
Query: 1050 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1109
LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV
Sbjct: 1067 LSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAV 1126
Query: 1110 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1169
FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK
Sbjct: 1127 FALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDK 1186
Query: 1170 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1229
DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY
Sbjct: 1187 DSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELY 1246
Query: 1230 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1289
DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG
Sbjct: 1247 DHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPG 1306
Query: 1290 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1349
FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL
Sbjct: 1307 FEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQL 1366
Query: 1350 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1409
ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR
Sbjct: 1367 ANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNR 1426
Query: 1410 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1469
QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI
Sbjct: 1427 QFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPI 1486
Query: 1470 Q---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQ 1508
Q EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQ
Sbjct: 1487 QLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQ 1546
Query: 1509 LENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFH 1568
LENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFH
Sbjct: 1547 LENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFH 1606
Query: 1569 QLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFG 1628
QLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFG
Sbjct: 1607 QLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFG 1666
Query: 1629 KMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSG 1688
KMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSG
Sbjct: 1667 KMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSG 1726
Query: 1689 PNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEE 1748
PNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEE
Sbjct: 1727 PNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEE 1786
Query: 1749 RLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRA 1808
RLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRA
Sbjct: 1787 RLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRA 1846
Query: 1809 RRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFN 1868
RRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFN
Sbjct: 1847 RRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFN 1906
Query: 1869 WRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLD 1928
WRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLD
Sbjct: 1907 WRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLD 1966
Query: 1929 LNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMT 1988
LNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMT
Sbjct: 1967 LNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMT 2026
Query: 1989 LEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAII 2048
LEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAII
Sbjct: 2027 LEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAII 2086
Query: 2049 LFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2080
LFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2087 LFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2118
>gi|195976766 dysferlin isoform 7 [Homo sapiens]
Length = 2112
Score = 4218 bits (10939), Expect = 0.0
Identities = 2060/2112 (97%), Positives = 2064/2112 (97%), Gaps = 32/2112 (1%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 153 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 209 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 269 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 329 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 389 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 449 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 508
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 540
Query: 509 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 568
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 541 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 600
Query: 569 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 628
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 601 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 660
Query: 629 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 688
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 661 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 720
Query: 689 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 748
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 721 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 780
Query: 749 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 808
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 781 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 840
Query: 809 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 868
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 841 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 900
Query: 869 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 928
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 901 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 960
Query: 929 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 988
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 961 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1020
Query: 989 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1048
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1021 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1080
Query: 1049 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1108
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1081 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1140
Query: 1109 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1168
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1141 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1200
Query: 1169 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1228
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1201 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1260
Query: 1229 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1288
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1261 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1320
Query: 1289 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1348
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1321 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1380
Query: 1349 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1408
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1381 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1440
Query: 1409 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1468
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1441 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1500
Query: 1469 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1528
IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1501 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1560
Query: 1529 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1588
RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1561 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1620
Query: 1589 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1648
GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1621 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1680
Query: 1649 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1708
DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1681 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1740
Query: 1709 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1768
HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1741 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1800
Query: 1769 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1828
PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1801 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1860
Query: 1829 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1888
SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1861 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1920
Query: 1889 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1948
KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1921 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1980
Query: 1949 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2008
DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1981 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2040
Query: 2009 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2068
PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2041 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2100
Query: 2069 NYAAMKLVKPFS 2080
NYAAMKLVKPFS
Sbjct: 2101 NYAAMKLVKPFS 2112
>gi|195976777 dysferlin isoform 3 [Homo sapiens]
Length = 2067
Score = 4196 bits (10883), Expect = 0.0
Identities = 2045/2081 (98%), Positives = 2050/2081 (98%), Gaps = 15/2081 (0%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
Query: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
Query: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
Query: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
Query: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
Query: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
Query: 480 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539
LSMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 481 LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 526
Query: 540 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 527 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 586
Query: 600 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 587 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 646
Query: 660 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 719
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 647 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 706
Query: 720 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 779
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 707 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 766
Query: 780 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 839
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 767 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 826
Query: 840 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 899
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 827 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 886
Query: 900 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 959
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 887 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 946
Query: 960 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1019
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 947 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1006
Query: 1020 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1079
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1007 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1066
Query: 1080 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1139
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1067 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1126
Query: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186
Query: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1259
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1246
Query: 1260 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1319
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1247 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1306
Query: 1320 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1379
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1307 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1366
Query: 1380 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1439
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1367 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1426
Query: 1440 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDF 1499
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDF
Sbjct: 1427 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDF 1486
Query: 1500 DTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPA 1559
DTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPA
Sbjct: 1487 DTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPA 1546
Query: 1560 IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYI 1619
IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYI
Sbjct: 1547 IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYI 1606
Query: 1620 PCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCG 1679
PCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCG
Sbjct: 1607 PCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCG 1666
Query: 1680 LPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIP 1739
LPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIP
Sbjct: 1667 LPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIP 1726
Query: 1740 NPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGP 1799
NPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGP
Sbjct: 1727 NPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGP 1786
Query: 1800 PFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYR 1859
PFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYR
Sbjct: 1787 PFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYR 1846
Query: 1860 SLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFD 1919
SLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFD
Sbjct: 1847 SLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFD 1906
Query: 1920 DFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKK 1979
DFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKK
Sbjct: 1907 DFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKK 1966
Query: 1980 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2039
ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL
Sbjct: 1967 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2026
Query: 2040 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2080
WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2027 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2067
>gi|195976773 dysferlin isoform 5 [Homo sapiens]
Length = 2088
Score = 4184 bits (10851), Expect = 0.0
Identities = 2045/2102 (97%), Positives = 2050/2102 (97%), Gaps = 36/2102 (1%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 180
Query: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP
Sbjct: 181 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 240
Query: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG
Sbjct: 241 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 300
Query: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE
Sbjct: 301 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 360
Query: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF
Sbjct: 361 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 420
Query: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY
Sbjct: 421 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 480
Query: 480 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539
LSMSKISAPGGEIE +DDYLGFLPTFGPCYINLYGSPREFTGFPDPY
Sbjct: 481 LSMSKISAPGGEIE--------------VDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 526
Query: 540 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599
TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY
Sbjct: 527 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 586
Query: 600 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659
SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV
Sbjct: 587 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 646
Query: 660 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 719
VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG
Sbjct: 647 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAG 706
Query: 720 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 779
CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL
Sbjct: 707 CSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLRL 766
Query: 780 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 839
RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP
Sbjct: 767 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 826
Query: 840 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 899
MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL
Sbjct: 827 MEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTGL 886
Query: 900 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 959
TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR
Sbjct: 887 TYPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQTR 946
Query: 960 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1019
LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP
Sbjct: 947 LPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSITIP 1006
Query: 1020 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1079
PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF
Sbjct: 1007 PERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEGEGWEYASLFGWKF 1066
Query: 1080 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1139
HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR
Sbjct: 1067 HLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVMDDKSEDSMSVSTLSFGVNR 1126
Query: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199
PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW
Sbjct: 1127 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1186
Query: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1259
DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP
Sbjct: 1187 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRLAWFP 1246
Query: 1260 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1319
LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY
Sbjct: 1247 LTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPYPPPQREANIY 1306
Query: 1320 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1379
MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN
Sbjct: 1307 MVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTVQSCVIRNLRKNPN 1366
Query: 1380 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1439
FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS
Sbjct: 1367 FDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLESFLCDPYSAESPS 1426
Query: 1440 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ---------------------EEEFIDWW 1478
PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ EEEFIDWW
Sbjct: 1427 PQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQLADGLSSLAPTNTASPPSSPHEEEFIDWW 1486
Query: 1479 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1538
SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED
Sbjct: 1487 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1546
Query: 1539 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1598
PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK
Sbjct: 1547 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1606
Query: 1599 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1658
CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK
Sbjct: 1607 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1666
Query: 1659 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1718
IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT
Sbjct: 1667 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1726
Query: 1719 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1778
DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI
Sbjct: 1727 DRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1786
Query: 1779 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1838
EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI
Sbjct: 1787 EQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDI 1846
Query: 1839 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1898
YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT
Sbjct: 1847 YVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKT 1906
Query: 1899 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1958
ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS
Sbjct: 1907 ESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVS 1966
Query: 1959 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2018
LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP
Sbjct: 1967 LFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDP 2026
Query: 2019 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2078
RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP
Sbjct: 2027 RRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2086
Query: 2079 FS 2080
FS
Sbjct: 2087 FS 2088
>gi|195976775 dysferlin isoform 4 [Homo sapiens]
Length = 2098
Score = 4180 bits (10841), Expect = 0.0
Identities = 2045/2112 (96%), Positives = 2050/2112 (97%), Gaps = 46/2112 (2%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 153 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 209 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 269 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 329 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 389 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 449 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 508
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526
Query: 509 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 568
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 527 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586
Query: 569 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 628
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 587 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646
Query: 629 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 688
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 647 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706
Query: 689 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 748
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 707 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
Query: 749 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 808
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
Query: 809 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 868
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
Query: 869 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 928
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946
Query: 929 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 988
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 947 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006
Query: 989 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1048
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066
Query: 1049 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1108
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126
Query: 1109 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1168
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186
Query: 1169 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1228
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246
Query: 1229 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1288
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306
Query: 1289 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1348
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366
Query: 1349 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1408
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426
Query: 1409 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1468
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486
Query: 1469 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1528
IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY
Sbjct: 1487 IQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLY 1546
Query: 1529 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1588
RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF
Sbjct: 1547 RGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAF 1606
Query: 1589 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1648
GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY
Sbjct: 1607 GLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLY 1666
Query: 1649 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1708
DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ
Sbjct: 1667 DYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQ 1726
Query: 1709 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1768
HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR
Sbjct: 1727 HRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESR 1786
Query: 1769 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1828
PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL
Sbjct: 1787 PLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDL 1846
Query: 1829 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1888
SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK
Sbjct: 1847 SLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAK 1906
Query: 1889 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1948
KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD
Sbjct: 1907 KDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLD 1966
Query: 1949 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2008
DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE
Sbjct: 1967 DAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDE 2026
Query: 2009 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2068
PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP
Sbjct: 2027 PNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFP 2086
Query: 2069 NYAAMKLVKPFS 2080
NYAAMKLVKPFS
Sbjct: 2087 NYAAMKLVKPFS 2098
>gi|195976779 dysferlin isoform 1 [Homo sapiens]
Length = 2119
Score = 4168 bits (10809), Expect = 0.0
Identities = 2045/2133 (95%), Positives = 2050/2133 (96%), Gaps = 67/2133 (3%)
Query: 1 MLRVFILYAENVHTPDTDI-SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 59
ML ++ A N+ + D SD S F GVKKRTKVIKNSVNPVWNEGFEWDLKGIPL
Sbjct: 1 MLCCLLVRASNLPSAKKDRRSDPVASLTFRGVKKRTKVIKNSVNPVWNEGFEWDLKGIPL 60
Query: 60 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 119
DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL
Sbjct: 61 DQGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA--------------------------- 152
QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVA
Sbjct: 121 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVAGGGQSRAETWSLLSDSTMDTRYSGKKW 180
Query: 153 ----DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 208
DTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT
Sbjct: 181 PAPTDTGGEEDTEDQGLTGDEAEPFLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPT 240
Query: 209 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 268
SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF
Sbjct: 241 SRKLLSDKPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKGNSPLFNETLFF 300
Query: 269 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 328
NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD
Sbjct: 301 NLFDSPGELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDD 360
Query: 329 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 388
FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA
Sbjct: 361 FSAGARGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRA 420
Query: 389 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 448
EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL
Sbjct: 421 EDLPQMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITL 480
Query: 449 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIEEEPAGAVKPSKASDL 508
PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE +
Sbjct: 481 PAMFPSMCEKMRIRIIDWDRLTHNDIVATTYLSMSKISAPGGEIE--------------V 526
Query: 509 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 568
DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS
Sbjct: 527 DDYLGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHS 586
Query: 569 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 628
EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC
Sbjct: 587 EQKVEDLPADDILRVEKYLRRRKYSLFAAFYSATMLQDVDDAIQFEVSIGNYGNKFDMTC 646
Query: 629 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 688
LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG
Sbjct: 647 LPLASTTQYSRAVFDGCHYYYLPWGNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAG 706
Query: 689 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 748
LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL
Sbjct: 707 LEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHETPSATHLDQYLYQLRTHHL 766
Query: 749 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 808
SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR
Sbjct: 767 SQITEAALALKLGHSELPAALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQR 826
Query: 809 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 868
VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN
Sbjct: 827 VPAHQVLFSRRGANYCGKNCGKLQTIFLKYPMEKVPGARMPVQIRVKLWFGLSVDEKEFN 886
Query: 869 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 928
QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG
Sbjct: 887 QFAEGKLSVFAETYENETKLALVGNWGTTGLTYPKFSDVTGKIKLPKDSFRPSAGWTWAG 946
Query: 929 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 988
DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC
Sbjct: 947 DWFVCPEKTLLHDMDAGHLSFVEEVFENQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIEC 1006
Query: 989 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1048
PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR
Sbjct: 1007 PLGWKWEDEEWSTDLNRAVDEQGWEYSITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRR 1066
Query: 1049 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1108
DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA
Sbjct: 1067 DLSQMEALKRHRQAEAEGEGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAA 1126
Query: 1109 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1168
VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD
Sbjct: 1127 VFALEGALGGVMDDKSEDSMSVSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMD 1186
Query: 1169 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1228
KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL
Sbjct: 1187 KDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVEL 1246
Query: 1229 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1288
YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP
Sbjct: 1247 YDHDTYGADEFMGRCICQPSLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIP 1306
Query: 1289 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1348
GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ
Sbjct: 1307 GFEVQETSRILDESEDTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQ 1366
Query: 1349 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1408
LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN
Sbjct: 1367 LANISSPSLVVECGGQTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDN 1426
Query: 1409 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1468
RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP
Sbjct: 1427 RQFGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIP 1486
Query: 1469 IQ---------------------EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1507
IQ EEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT
Sbjct: 1487 IQLADGLSSLAPTNTASPPSSPHEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDT 1546
Query: 1508 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1567
QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF
Sbjct: 1547 QLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQF 1606
Query: 1568 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1627
HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF
Sbjct: 1607 HQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVF 1666
Query: 1628 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1687
GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS
Sbjct: 1667 GKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVS 1726
Query: 1688 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1747
GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE
Sbjct: 1727 GPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVMFQDKEYSIEEIEAGRIPNPHLGPVE 1786
Query: 1748 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1807
ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR
Sbjct: 1787 ERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRR 1846
Query: 1808 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1867
ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF
Sbjct: 1847 ARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNF 1906
Query: 1868 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1927
NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL
Sbjct: 1907 NWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQL 1966
Query: 1928 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 1987
DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM
Sbjct: 1967 DLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEM 2026
Query: 1988 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2047
TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI
Sbjct: 2027 TLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAI 2086
Query: 2048 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2080
ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS
Sbjct: 2087 ILFIILFILLLFLAIFIYAFPNYAAMKLVKPFS 2119
>gi|7305053 myoferlin isoform a [Homo sapiens]
Length = 2061
Score = 2379 bits (6165), Expect = 0.0
Identities = 1177/2108 (55%), Positives = 1512/2108 (71%), Gaps = 79/2108 (3%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRV + A N+ D S +F KK+TK + N +NPVWNE E+DL+GIPLD
Sbjct: 1 MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLVL 119
S L ++VKD ET+G+N+ +G A V L+++ S S + LL+ K Q TGA++ L
Sbjct: 61 FSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
+ Y P P P P L P++P + GEED D+ + G
Sbjct: 121 VIGYDP-----PSAPHPNDLS-GPSVPGMG----GDGEEDEGDEDRLDNAVR-------G 163
Query: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
PG K P +R SR++LS+KPQDFQIRV+VIEGRQL G NI+P
Sbjct: 164 PGP-----KGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRP 218
Query: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
VVKV GQT RTRI +GN+P F+E F+N+ +P EL DE I I V +S SLR D L+G
Sbjct: 219 VVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLMG 278
Query: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
EF++DVG +Y EP HA +RKWLLL+DP+D S+G++GY+K S+ VLG GDE P ER+D
Sbjct: 279 EFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRDN 338
Query: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
D +D+ESNLL P G+ALR F LK++RAED+PQMDDA VK+IFG ++KKNLVDPF
Sbjct: 339 DSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPF 398
Query: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
VEVSFAGK +C+ I+EK ANP+WNQ + L FPS+CEK+++ I DWDRLT ND+V TTY
Sbjct: 399 VEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTY 458
Query: 480 LSMSKISAPGGEIEEEPAGAVKPSK--ASDLDDYLGFLPTFGPCYINLYGSPREFTGFPD 537
L +SKI+A GGE+E+ + + + + +GF+PTFGPCY+NLYGSPRE+TGFPD
Sbjct: 459 LHLSKIAASGGEVEDFSSSGTGAASYTVNTGETEVGFVPTFGPCYLNLYGSPREYTGFPD 518
Query: 538 PYTELNTGKGEGVAYRGRLLLSLETKLVE-HSEQKVEDLPADDILRVEKYLRRRKYSLFA 596
PY ELNTGKGEGVAYRGR+L+ L T L + ++K+E + DD+L VEKY RRRKYSL A
Sbjct: 519 PYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSA 578
Query: 597 AFYSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVK 656
F+SATMLQDV +AIQFEVSIGNYGNKFD TC PLASTTQYSRAVFDG +YYYLPW + K
Sbjct: 579 VFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTK 638
Query: 657 PVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDEL 716
PVV L+SYWEDISHR++ N LL +A+RL+ +E + ++ + + L +L DE+
Sbjct: 639 PVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEV 698
Query: 717 IAGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWL 776
I L + T LD + +LR+ LSQI EAA+ ++ +++ + L + EDWL
Sbjct: 699 IEDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWL 758
Query: 777 LRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFL 836
+L L EEPQNS+PDI+IWM++G+KR+AY R+PAHQVL+S G N GK CGK QTIFL
Sbjct: 759 DKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFL 818
Query: 837 KYPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGT 896
KYP EK G ++PV++RV +W GLS EK+FN FAEG +VFAE YEN+ + G WGT
Sbjct: 819 KYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQA--LMFGKWGT 876
Query: 897 TGLT-YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFE 955
+GL KFSDVTGKIKL ++ F P GW W G+W V PE++LL + DAGH F +EV++
Sbjct: 877 SGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQ 936
Query: 956 NQTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYS 1015
N++R PGG W D YTD NG+K ++ CP GW+WED+ WS D+NRAVDE+GWEY
Sbjct: 937 NESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYG 996
Query: 1016 ITIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEG-EGWEYASL 1074
ITIPP+ KPK WV AEKMY+THRRRR VR R++DL+Q + E + EGWEYASL
Sbjct: 997 ITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYASL 1056
Query: 1075 FGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVM----DDKS-EDSMS 1129
GWKFH + R +D FRRRRWRR+M P E G AA+F LEGALG D+KS E
Sbjct: 1057 IGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKH 1116
Query: 1130 VSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTV 1189
+T FG N P +SC FD YHLRCY+YQAR+L A+DKDSFSDPYA + FLH+S+ T
Sbjct: 1117 SATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTE 1176
Query: 1190 VVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQP-- 1247
++ +TLNPTWDQT+IF E+EI+GEP TV + PP +++EL+D+D G DEF+GR I P
Sbjct: 1177 IIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPVV 1236
Query: 1248 ----SLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1303
++ P+L W P+ G + G++L + ELI R K +
Sbjct: 1237 KLNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGK---------------------D 1275
Query: 1304 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1363
++LP PPQR N+YMVPQ I+P +Q TAIEILAWGLRNMK++Q+A+I+SPSLVVECGG
Sbjct: 1276 GSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECGG 1335
Query: 1364 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1423
+ V+S VI+NL+K PNF LFM+V LP+EELY PP+ +KVID+RQFGR+PVVGQCTI
Sbjct: 1336 ERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIE 1395
Query: 1424 SLESFLCDPYSA-ESPSPQGGPDDVSLLS--PGEDVLIDIDDKEPLIPI----QEEEFID 1476
L+ F CDPY+ E PQ SLLS P D++I+++D +PL+ +EEE +D
Sbjct: 1396 RLDRFRCDPYAGKEDIVPQ---LKASLLSAPPCRDIVIEMEDTKPLLASKLTEKEEEIVD 1452
Query: 1477 WWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEET 1536
WWSKF+AS GE EKCG Y++K + LK+Y+ +LENV FEGL+DF +TFKLYRGK+ +E
Sbjct: 1453 WWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFSDTFKLYRGKS-DEN 1511
Query: 1537 EDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPN 1596
EDPSV+GEFKG F+IYPLP+DP++P PPRQF +L PQEC VRIYIVR LQP+D N
Sbjct: 1512 EDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVRGLELQPQDNN 1571
Query: 1597 GKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKD 1656
G CDPYIKI++GKK + D+D+YIP TL PVFG+M+EL+C LP EKDLKI++YDYD ++D
Sbjct: 1572 GLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVYDYDTFTRD 1631
Query: 1657 EKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY 1716
EK+GET++DLENR LS+FG+ CG+P+ YCVSG N WRDQLRP+QLL + P+
Sbjct: 1632 EKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQLLQNVARFKGFPQPIL 1691
Query: 1717 RTD--RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPL 1774
D R+ + ++YS++E EA +I + HLG EERLALH+L+ QGLVPEHVE+R L+S
Sbjct: 1692 SEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRTLHSTF 1751
Query: 1775 QPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEK 1834
QP+I QGKLQMWVD+FPK+LG PGPPFNITPR+A++++LR IIWNT+DVILD+ S+TGE+
Sbjct: 1752 QPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWNTKDVILDEKSITGEE 1811
Query: 1835 MSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWR 1894
MSDIYVKGW+ G EE+KQKTDVHYRSL GEGNFNWRF+FPFDYLPAEQ+C +AKK+ FW
Sbjct: 1812 MSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQLCIVAKKEHFWS 1871
Query: 1895 LDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD--AFH 1952
+D+TE +IP R++ QIWDNDKFS DD+LG L+LDL PAK+ +KC LD + D A +
Sbjct: 1872 IDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSPEKCRLDMIPDLKAMN 1931
Query: 1953 P--EWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPN 2010
P SLFEQK++KGWWPC AE+ +++AGK+EMTLEI+ E E +ERPAG+GRDEPN
Sbjct: 1932 PLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNEKEADERPAGKGRDEPN 1991
Query: 2011 MNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNY 2070
MNPKL+ P RP+TSFLWFT+P KTMKFI+WRRF+W II + L ILLLF+A+ +Y+ PNY
Sbjct: 1992 MNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLLILLLFVAVLLYSLPNY 2051
Query: 2071 AAMKLVKP 2078
+MK+VKP
Sbjct: 2052 LSMKIVKP 2059
>gi|19718759 myoferlin isoform b [Homo sapiens]
Length = 2048
Score = 2377 bits (6160), Expect = 0.0
Identities = 1177/2106 (55%), Positives = 1508/2106 (71%), Gaps = 88/2106 (4%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLRV + A N+ D S +F KK+TK + N +NPVWNE E+DL+GIPLD
Sbjct: 1 MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLD 60
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA-PLLDTKKQPTGASLVL 119
S L ++VKD ET+G+N+ +G A V L+++ S S + LL+ K Q TGA++ L
Sbjct: 61 FSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDL 120
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
+ Y P P P P L P++P + GEED D+ + G
Sbjct: 121 VIGYDP-----PSAPHPNDLS-GPSVPGMG----GDGEEDEGDEDRLDNAVR-------G 163
Query: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
PG K P +R SR++LS+KPQDFQIRV+VIEGRQL G NI+P
Sbjct: 164 PGP-----KGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRP 218
Query: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
VVKV GQT RTRI +GN+P F+E F+N+ +P EL DE I I V +S SLR D L+G
Sbjct: 219 VVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLMG 278
Query: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
EF++DVG +Y EP HA +RKWLLL+DP+D S+G++GY+K S+ VLG GDE P ER+D
Sbjct: 279 EFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRDN 338
Query: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
D +D+ESNLL P G+ALR F LK++RAED+PQMDDA VK+IFG ++KKNLVDPF
Sbjct: 339 DSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPF 398
Query: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
VEVSFAGK +C+ I+EK ANP+WNQ + L FPS+CEK+++ I DWDRLT ND+V TTY
Sbjct: 399 VEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTY 458
Query: 480 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539
L +SKI+A GGE+E + +GF+PTFGPCY+NLYGSPRE+TGFPDPY
Sbjct: 459 LHLSKIAASGGEVEVNTG-----------ETEVGFVPTFGPCYLNLYGSPREYTGFPDPY 507
Query: 540 TELNTGKGEGVAYRGRLLLSLETKLVE-HSEQKVEDLPADDILRVEKYLRRRKYSLFAAF 598
ELNTGKGEGVAYRGR+L+ L T L + ++K+E + DD+L VEKY RRRKYSL A F
Sbjct: 508 DELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVF 567
Query: 599 YSATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPV 658
+SATMLQDV +AIQFEVSIGNYGNKFD TC PLASTTQYSRAVFDG +YYYLPW + KPV
Sbjct: 568 HSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPV 627
Query: 659 VVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIA 718
V L+SYWEDISHR++ N LL +A+RL+ +E + ++ + + L +L DE+I
Sbjct: 628 VTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEVIE 687
Query: 719 GCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLLR 778
L + T LD + +LR+ LSQI EAA+ ++ +++ + L + EDWL +
Sbjct: 688 DTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDK 747
Query: 779 LRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKY 838
L L EEPQNS+PDI+IWM++G+KR+AY R+PAHQVL+S G N GK CGK QTIFLKY
Sbjct: 748 LMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFLKY 807
Query: 839 PMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTTG 898
P EK G ++PV++RV +W GLS EK+FN FAEG +VFAE YEN+ + G WGT+G
Sbjct: 808 PQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQA--LMFGKWGTSG 865
Query: 899 LT-YPKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFENQ 957
L KFSDVTGKIKL ++ F P GW W G+W V PE++LL + DAGH F +EV++N+
Sbjct: 866 LVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQNE 925
Query: 958 TRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSIT 1017
+R PGG W D YTD NG+K ++ CP GW+WED+ WS D+NRAVDE+GWEY IT
Sbjct: 926 SRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYGIT 985
Query: 1018 IPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQAEAEG-EGWEYASLFG 1076
IPP+ KPK WV AEKMY+THRRRR VR R++DL+Q + E + EGWEYASL G
Sbjct: 986 IPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYASLIG 1045
Query: 1077 WKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGALGGVM----DDKS-EDSMSVS 1131
WKFH + R +D FRRRRWRR+M P E G AA+F LEGALG D+KS E +
Sbjct: 1046 WKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKHSA 1105
Query: 1132 TLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVV 1191
T FG N P +SC FD YHLRCY+YQAR+L A+DKDSFSDPYA + FLH+S+ T ++
Sbjct: 1106 TTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTEII 1165
Query: 1192 KNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQP---- 1247
+TLNPTWDQT+IF E+EI+GEP TV + PP +++EL+D+D G DEF+GR I P
Sbjct: 1166 HSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKL 1225
Query: 1248 --SLERMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDT 1305
++ P+L W P+ G + G++L + ELI R K + +
Sbjct: 1226 NSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGK---------------------DGS 1264
Query: 1306 DLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQT 1365
+LP PPQR N+YMVPQ I+P +Q TAIEILAWGLRNMK++Q+A+I+SPSLVVECGG+
Sbjct: 1265 NLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECGGER 1324
Query: 1366 VQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSL 1425
V+S VI+NL+K PNF LFM+V LP+EELY PP+ +KVID+RQFGR+PVVGQCTI L
Sbjct: 1325 VESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIERL 1384
Query: 1426 ESFLCDPYSA-ESPSPQGGPDDVSLLS--PGEDVLIDIDDKEPLIPI----QEEEFIDWW 1478
+ F CDPY+ E PQ SLLS P D++I+++D +PL+ +EEE +DWW
Sbjct: 1385 DRFRCDPYAGKEDIVPQ---LKASLLSAPPCRDIVIEMEDTKPLLASKLTEKEEEIVDWW 1441
Query: 1479 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1538
SKF+AS GE EKCG Y++K + LK+Y+ +LENV FEGL+DF +TFKLYRGK+ +E ED
Sbjct: 1442 SKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFSDTFKLYRGKS-DENED 1500
Query: 1539 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGK 1598
PSV+GEFKG F+IYPLP+DP++P PPRQF +L PQEC VRIYIVR LQP+D NG
Sbjct: 1501 PSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVRGLELQPQDNNGL 1560
Query: 1599 CDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEK 1658
CDPYIKI++GKK + D+D+YIP TL PVFG+M+EL+C LP EKDLKI++YDYD ++DEK
Sbjct: 1561 CDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVYDYDTFTRDEK 1620
Query: 1659 IGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRT 1718
+GET++DLENR LS+FG+ CG+P+ YCVSG N WRDQLRP+QLL + P+
Sbjct: 1621 VGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQLLQNVARFKGFPQPILSE 1680
Query: 1719 D--RVMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQP 1776
D R+ + ++YS++E EA +I + HLG EERLALH+L+ QGLVPEHVE+R L+S QP
Sbjct: 1681 DGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRTLHSTFQP 1740
Query: 1777 DIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMS 1836
+I QGKLQMWVD+FPK+LG PGPPFNITPR+A++++LR IIWNT+DVILD+ S+TGE+MS
Sbjct: 1741 NISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWNTKDVILDEKSITGEEMS 1800
Query: 1837 DIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLD 1896
DIYVKGW+ G EE+KQKTDVHYRSL GEGNFNWRF+FPFDYLPAEQ+C +AKK+ FW +D
Sbjct: 1801 DIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQLCIVAKKEHFWSID 1860
Query: 1897 KTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDD--AFHP- 1953
+TE +IP R++ QIWDNDKFS DD+LG L+LDL PAK+ +KC LD + D A +P
Sbjct: 1861 QTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSPEKCRLDMIPDLKAMNPL 1920
Query: 1954 -EWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMN 2012
SLFEQK++KGWWPC AE+ +++AGK+EMTLEI+ E E +ERPAG+GRDEPNMN
Sbjct: 1921 KAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNEKEADERPAGKGRDEPNMN 1980
Query: 2013 PKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAA 2072
PKL+ P RP+TSFLWFT+P KTMKFI+WRRF+W II + L ILLLF+A+ +Y+ PNY +
Sbjct: 1981 PKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLLILLLFVAVLLYSLPNYLS 2040
Query: 2073 MKLVKP 2078
MK+VKP
Sbjct: 2041 MKIVKP 2046
>gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]
Length = 2093
Score = 1436 bits (3717), Expect = 0.0
Identities = 858/2181 (39%), Positives = 1219/2181 (55%), Gaps = 255/2181 (11%)
Query: 1 MLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
MLR+ + A+ + P + S F +KKRT+V++ + +PVWNE W L PL+
Sbjct: 1 MLRLVVQSAK-IDPPLAPLPRPCMSIDFRDIKKRTRVVEGN-DPVWNETLIWHLWNRPLE 58
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREVLATPS-LSASFNAPLLDTKKQPTGASLVL 119
S L V ++D + + RF+G A V L+ +L PS + + LL+ +PT ++ L
Sbjct: 59 NDSFLQVTLQDMGSQKKERFIGLATVLLKPLLKQPSEVLFVKDLTLLNHSMKPTDCTVTL 118
Query: 120 QVSYTPLPGAVPLFPPPTPLEPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPFLDQSGG 179
QV++ + + D+ TG E+ G+T EA
Sbjct: 119 QVAH---------------------MSNQDI-EKTGAEDHL---GITAREA--------- 144
Query: 180 PGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQIRVQVIEGRQLPGVNIKP 239
+KL PG T+ + LS KPQ FQ+RV+V E RQL G NIKP
Sbjct: 145 -----ASQKLM------VPG-------STAHRALSSKPQHFQVRVKVFEARQLMGNNIKP 186
Query: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299
VVKV+ AGQ +TRI GN+P FNE F N + P + FDE I I
Sbjct: 187 VVKVSIAGQQHQTRIKMGNNPFFNEIFFQNFHEVPAKFFDETILI--------------- 231
Query: 300 EFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLKTSLCVLGPGDEAPLERKDPSE 359
+ D+G IY P H LRKWL L P++ +G GYLK ++ LG GD+A +++K
Sbjct: 232 --QTDIGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKVTIYALGVGDQALIDQK-LLY 288
Query: 360 DKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFESNKKNLVDPF 419
+D + + + V + A+ L ++ AEDL K V+P
Sbjct: 289 GTDDTDIQIFKSAVVPINMAYLQLFIYCAEDL-----------------HLKKHQSVNPQ 331
Query: 420 VEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIVATTY 479
+EV G+ L + + +T NP WNQ +T P + ++ R++D + D + T
Sbjct: 332 LEVELIGEKLRTHMQTQTDNPIWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGTAS 391
Query: 480 LSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFLPTFGPCYINLYGSPREFTGFPDPY 539
LS+++IS+ G EIE + + ++P+ + Y GFLP FGP ++ L+G + +
Sbjct: 392 LSLNQISSTGEEIEGKQS--LEPTSYTPRV-YSGFLPCFGPSFLTLHGGKKAPFRIQEEG 448
Query: 540 TELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDLPADDILRVEKYLRRRKYSLFAAFY 599
+ +G+AYRGR+ L L T++ + + ++DL + ++ R+EK+ R+KY L F
Sbjct: 449 ACIPDSVRDGLAYRGRVFLELITQIKSYQDSTIKDL-SHEVTRIEKHQNRQKYGLCVIFL 507
Query: 600 SATMLQDVDDAIQFEVSIGNYGNKFDMTCLPLASTTQYSRAVFDGCHYYYLPWGNVKPVV 659
S TM+ + + I FEVSIG+YGNK D+ PL S+T YS ++DG Y+Y+PW N KPVV
Sbjct: 508 SCTMMPNFKELIHFEVSIGHYGNKMDLNYKPLVSSTPYSPVIYDGNIYHYVPWYNTKPVV 567
Query: 660 VLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVA--QLTDELI 717
++S WED+S R+ N L DRL+A L+ LK+ + +D L +L EL
Sbjct: 568 AVTSNWEDVSFRMNCLNLLHFTRDRLKANLD----TLKSTRNPKDPALLYQWEKLLRELA 623
Query: 718 AGCSQPLGDIHETPSATHLDQYLYQLRTHHLSQITEAALALKLGHSELPAALEQAEDWLL 777
C +PL + P AT LD+ +QLR+ L + LA K ++ + AEDWL
Sbjct: 624 EDCKRPLPCMTYQPKATSLDRKRWQLRSLLLQE-----LAQKAKQAKPKDMVATAEDWLY 678
Query: 778 RLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLK 837
RL + EPQ LPD++IW++ ++RVAY +VPAH VLFS GA + G+ CGK+QT+FL+
Sbjct: 679 RLNTVLPEPQMGLPDVMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQ 738
Query: 838 YPMEKVPGARMPVQIRVKLWFGLSVDEKEFNQFAEGKLSVFAETYENETKLALVGNWGTT 897
YP + +P +RV +W G D K+ +G +V+AE YEN+ K WG
Sbjct: 739 YPEGEGQKDVLPAHLRVCMWLGNVTDSKDLQLLRQGDTAVYAEMYENQAKYK--DQWGQQ 796
Query: 898 GLTY-PKFSDVTGKIKLPKDSFRPSAGWTWAGDWFVCPEKTLLHDMDAGHLSFVEEVFEN 956
GL + P FSDV G LP F+P GW W W V P++ LL D+D +EEV+EN
Sbjct: 797 GLYHCPNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYEN 856
Query: 957 QTRLPGGQWIYMSDNYTDVNGEKVLPKDDIECPLGWKWEDEEWSTDLNRAVDEQGWEYSI 1016
Q R G W + TDVNG+ + +++++CP GW ++ ++W +LN AVD WEY +
Sbjct: 857 QGRDTRGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFK-KDWVVELNHAVDS--WEYGV 913
Query: 1017 TIPPERKPKHWVPAEKMYYTHRRRRWVRLRRRDLSQMEALKRHRQ----------AEAEG 1066
IPP P+ W P EK Y++ RRRRW R+R R+ ++ H Q A+ E
Sbjct: 914 GIPPSGLPQVWSPVEKTYHSCRRRRWARVRFRNHGELS----HEQETLSFLQLGLAKGEE 969
Query: 1067 EGWEYASLFGWKFHLEYRKTDAFRRRRWRRRMEPLEKTGPAAVFALEGAL----GGVMDD 1122
EGWEY + FG KFHL + FRRR WRRR+ P + G A +F LEG+L G V ++
Sbjct: 970 EGWEYDT-FGSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEGGSVREE 1028
Query: 1123 ---------------------------------KSEDSMSVSTLSFGVNR---------- 1139
K EDS T +G++R
Sbjct: 1029 GDWAWARGNRSSTQEPQGRLSWVQAMDLKYHAGKEEDS---KTWPWGLDRQFRDPQRQDT 1085
Query: 1140 -----PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNT 1194
P I C F+ + Y L CY+YQAR+L + +F P+ V FL+ SQ T ++++
Sbjct: 1086 RPPNLPFIYCTFNKPHYYQLFCYIYQARNLVSNQILTFQGPFIRVVFLNHSQCTQTLRSS 1145
Query: 1195 LNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL----- 1249
PTW QTLIF + ++ P E PP +V+EL+ D +G + GR + P +
Sbjct: 1146 AGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRDFWGKESLWGRSVWPPMVWLDLQ 1205
Query: 1250 -ERMPRLAWFPLTRG-SQPSGELLASFELI-QREKPAIHHIPGFEVQETSRILDESEDTD 1306
+P + W PL + + GE+LAS ELI Q EK +P V
Sbjct: 1206 DRILPPMRWHPLVKELGKEEGEILASCELILQTEKLGEKQLPILSV-------------- 1251
Query: 1307 LPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1366
P+ + Y +P++I+P ++R AIEILAWGLRNMK SSP L+VE G +++
Sbjct: 1252 -PW-----KNGAYTLPKSIQPTIKRMAIEILAWGLRNMKK-----ASSPQLLVEFGEESL 1300
Query: 1367 QSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRS 1424
++ IR+ + NPNF L + V++P EE Y P+ VKV+DN FG++ V GQ I
Sbjct: 1301 RTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF 1360
Query: 1425 LESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----EPLIPIQEEEFIDWW 1478
L+ + CDP++ + P+ + LS +D L + K + E +DWW
Sbjct: 1361 LQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKSSKAEDEYEHEVDWW 1415
Query: 1479 SKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETED 1538
SK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC TFKLY+ ++ D
Sbjct: 1416 SKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQ---EQPKLD 1471
Query: 1539 PSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRIYIVRAFGLQPKDPN 1596
V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+Y+VRA LQP+D N
Sbjct: 1472 SPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYN 1531
Query: 1597 GKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKD 1656
G CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKDL+I LYD+DL S D
Sbjct: 1532 GLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPD 1591
Query: 1657 EKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY 1716
+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL + ++ + P++
Sbjct: 1592 DKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLF 1651
Query: 1717 --RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQGLVPEHVESRPLYSP 1773
D V + K++ ++ E + P H LGP +ERLAL++L QGLVPEHVE+R LYS
Sbjct: 1652 SPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQGLVPEHVETRTLYSH 1710
Query: 1774 LQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRAR---------RFFLRCIIWNTRDVI 1824
QP I+QGK+QMWVD+FPK LG PGP NI PR+ + R+ LRCIIW T +V
Sbjct: 1711 SQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCIIWKTANVD 1770
Query: 1825 LDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVC 1884
L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL AE+ C
Sbjct: 1771 LVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTC 1830
Query: 1885 TIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSL 1944
++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ AK+CS+
Sbjct: 1831 VQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSI 1890
Query: 1945 DQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEH 1997
+D P+W SLF++KTV GWWPC +G K L+GK++M+LEI++E E
Sbjct: 1891 RMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEA 1948
Query: 1998 EERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILL 2057
+PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F+++ I+
Sbjct: 1949 LIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIA 2008
Query: 2058 LFLAIFIYAFPNYAAMKLVKP 2078
L L FIY+ P+Y AM +KP
Sbjct: 2009 LMLFNFIYSAPHYLAMSWIKP 2029
>gi|35493868 otoferlin isoform b [Homo sapiens]
Length = 1230
Score = 720 bits (1858), Expect = 0.0
Identities = 408/1057 (38%), Positives = 584/1057 (55%), Gaps = 149/1057 (14%)
Query: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 201 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260
Query: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1252
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 261 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320
Query: 1253 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1309
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 321 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360
Query: 1310 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1366
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 361 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420
Query: 1367 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1426
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 421 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480
Query: 1427 SFLCDPYSAESPSPQGGPDDVSLLSPG---------------EDVLIDID---------- 1461
F+ P +PS + V + P + ++ +D
Sbjct: 481 RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540
Query: 1462 -----DKEPLIPIQEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1498
+EP +E +DWWSK+FASI ++E G LE+
Sbjct: 541 KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600
Query: 1499 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1521
D LKVY +LE+ F+ D+
Sbjct: 601 SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658
Query: 1522 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1571
+TF L RGKT ++ TE+ ++G FKG +Y PLPED + F +
Sbjct: 659 LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718
Query: 1572 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1631
+ P LVR+Y+VRA L P D NGK DPYI I +GK + D++NYI L PVFGK F
Sbjct: 719 SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778
Query: 1632 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1691
++ + P+E L + +YD+DL+ D+ IGET +DLENR SK A CG+ QTY G N
Sbjct: 779 DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838
Query: 1692 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1749
WRD ++PSQ+L C+ +V P + RV ++ ++ EIE N P +E
Sbjct: 839 WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895
Query: 1750 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1801
+AL L+ LVPEHVE+RPL +P +P IEQG+L++WVD+FP + PG P
Sbjct: 896 VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955
Query: 1802 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1860
+I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956 DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015
Query: 1861 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1920
L GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE KIPAR+ QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075
Query: 1921 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 1979
FLG+++LDLNR P+ AKTAK+C+++ VS+F+QK VKGWWP +A E ++
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134
Query: 1980 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2039
L GK+E L ++ E E+ P G R+EP+ LE P RPDTSF+WF +P K+ ++ L
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTSFIWFLNPLKSARYFL 1191
Query: 2040 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2076
W +RW ++ ++L +LLL LA+F+Y+ P Y K++
Sbjct: 1192 WHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1228
Score = 87.4 bits (215), Expect = 1e-16
Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)
Query: 714 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 768
+EL GC + L D + S+ T LD+ + L + + A L+ + +
Sbjct: 18 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77
Query: 769 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 828
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C
Sbjct: 78 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136
Query: 829 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 867
K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 408 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 444
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262
>gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]
Length = 802
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 1353 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1410
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
Query: 1411 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1464
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
Query: 1465 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1524
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
Query: 1525 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1582
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
Query: 1583 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1642
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Query: 1643 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1702
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
Query: 1703 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1759
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
Query: 1760 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1819
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
Query: 1820 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1879
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
Query: 1880 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1939
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
Query: 1940 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 1992
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
Query: 1993 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2052
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
Query: 2053 LFILLLFLAIFIYAFPNYAAMKLVKP 2078
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
>gi|35493853 otoferlin isoform c [Homo sapiens]
Length = 1307
Score = 712 bits (1839), Expect = 0.0
Identities = 410/1077 (38%), Positives = 584/1077 (54%), Gaps = 169/1077 (15%)
Query: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 258 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 317
Query: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1252
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 318 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 377
Query: 1253 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1309
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 378 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 417
Query: 1310 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1366
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 418 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 477
Query: 1367 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1426
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 478 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 537
Query: 1427 SFLCDPYSAESPS--------------PQGGPDDVSL---------------------LS 1451
F+ P +PS GG S L
Sbjct: 538 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLD 597
Query: 1452 PGEDVLIDID---------------DKEPLIPIQEEEFIDWWSKFFASIG-------ERE 1489
+ ++ +D +EP +E +DWWSK+FASI ++E
Sbjct: 598 ATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQE 657
Query: 1490 KCGSYLEKD------------------------------------------------FDT 1501
G LE+ D
Sbjct: 658 PSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDE 717
Query: 1502 LKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLP 1555
LKVY +LE+ F+ D+ +TF L RGKT ++ TE+ ++G FKG +Y PLP
Sbjct: 718 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 775
Query: 1556 EDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKS 1611
ED + F + + P LVR+Y+VRA L P D NGK DPYI I +GK
Sbjct: 776 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 835
Query: 1612 VSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLL 1671
+ D++NYI L PVFGK F++ + P+E L + +YD+DL+ D+ IGET +DLENR
Sbjct: 836 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 895
Query: 1672 SKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS- 1729
SK A CG+ QTY G N WRD ++PSQ+L C+ +V P + RV ++ ++
Sbjct: 896 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 955
Query: 1730 IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQG 1781
EIE N P +E +AL L+ LVPEHVE+RPL +P +P IEQG
Sbjct: 956 PSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQG 1012
Query: 1782 KLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYV 1840
+L++WVD+FP + PG P +I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V
Sbjct: 1013 RLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFV 1072
Query: 1841 KGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTES 1900
+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE
Sbjct: 1073 RGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEY 1132
Query: 1901 KIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLF 1960
KIPAR+ QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++ VS+F
Sbjct: 1133 KIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIF 1191
Query: 1961 EQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2019
+QK VKGWWP +A E ++ L GK+E L ++ E E+ P G R+EP+ LE P
Sbjct: 1192 KQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPN 1248
Query: 2020 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2076
RPDTSF+WF +P K+ ++ LW +RW ++ ++L +LLL LA+F+Y+ P Y K++
Sbjct: 1249 RPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1305
Score = 91.3 bits (225), Expect = 9e-18
Identities = 71/211 (33%), Positives = 110/211 (52%), Gaps = 21/211 (9%)
Query: 665 WEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQ-- 722
W I+H ++Q E GL + +K + S + + + +EL GC +
Sbjct: 38 WPSITHTPDSQ----------EEGLNDIQEMIKTEKSYPE--RRLRGVLEELSCGCCRFL 85
Query: 723 PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAALEQAEDWLLRL 779
L D + S+ T LD+ + L + + A L+ + + L +++L +L
Sbjct: 86 SLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKL 145
Query: 780 RALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYP 839
R LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C K++T+FLK P
Sbjct: 146 RFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDCAKVKTLFLKLP 204
Query: 840 MEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 867
++ G A VQ +V+ LW GLS KEF
Sbjct: 205 GKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 235
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 408 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 444
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 283 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 319
>gi|35493860 otoferlin isoform d [Homo sapiens]
Length = 1230
Score = 712 bits (1839), Expect = 0.0
Identities = 406/1057 (38%), Positives = 583/1057 (55%), Gaps = 149/1057 (14%)
Query: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 201 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 260
Query: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1252
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 261 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 320
Query: 1253 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1309
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 321 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 360
Query: 1310 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1366
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 361 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 420
Query: 1367 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1426
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 421 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 480
Query: 1427 SFLCDPYSAESPSPQGGPDDVSLLSPG---------------EDVLIDID---------- 1461
F+ P +PS + V + P + ++ +D
Sbjct: 481 RFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKEKKK 540
Query: 1462 -----DKEPLIPIQEEEFIDWWSKFFASIG-------EREKCGSYLEKD----------- 1498
+EP +E +DWWSK+FASI ++E G LE+
Sbjct: 541 KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKG 600
Query: 1499 -------------------------------------FDTLKVYDTQLENVEAFEGLSDF 1521
D LKVY +LE+ F+ D+
Sbjct: 601 SMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELES--EFDNFEDW 658
Query: 1522 CNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLPEDPA----IPMPPRQFHQLA 1571
+TF L RGKT ++ TE+ ++G FKG +Y PLPED + F +
Sbjct: 659 LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIP 718
Query: 1572 AQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMF 1631
+ P LVR+Y+VRA L P D NGK DPYI I +GK + D++NYI L PVFGK F
Sbjct: 719 SNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 778
Query: 1632 ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQ 1691
++ + P+E L + +YD+DL+ D+ IGET +DLENR SK A CG+ QTY G N
Sbjct: 779 DIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNI 838
Query: 1692 WRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS-IEEIEAGRIPNPHLGPVEER 1749
WRD ++PSQ+L C+ +V P + RV ++ ++ EIE N P +E
Sbjct: 839 WRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIED---ENGQRKPTDEH 895
Query: 1750 LALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1801
+AL L+ LVPEHVE+RPL +P +P IEQG+L++WVD+FP + PG P
Sbjct: 896 VALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPL 955
Query: 1802 NITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRS 1860
+I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V+GW+ G +E KQ TDVHY S
Sbjct: 956 DISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHS 1015
Query: 1861 LGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDD 1920
L GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE KIPAR+ QIWD D FS DD
Sbjct: 1016 LTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADD 1075
Query: 1921 FLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLFEQKTVKGWWPCVA-EEGEKK 1979
FLG+++LDLNR P+ AKTAK+C+++ VS+F+QK VKGWWP +A E ++
Sbjct: 1076 FLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIFKQKRVKGWWPLLARNENDEF 1134
Query: 1980 ILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFIL 2039
L GK+E L ++ E E+ P G R+EP+ LE P RPDT+F+WF +P K++K+++
Sbjct: 1135 ELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPNRPDTAFVWFLNPLKSIKYLI 1191
Query: 2040 WRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2076
R++W II ++ + LL L +F+Y+ P Y KL+
Sbjct: 1192 CTRYKWLIIKIVLALLGLLMLGLFLYSLPGYMVKKLL 1228
Score = 87.4 bits (215), Expect = 1e-16
Identities = 62/162 (38%), Positives = 92/162 (56%), Gaps = 9/162 (5%)
Query: 714 DELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAALALK--LGHSELPAA 768
+EL GC + L D + S+ T LD+ + L + + A L+ + +
Sbjct: 18 EELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDK 77
Query: 769 LEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNC 828
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+C
Sbjct: 78 LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKDC 136
Query: 829 GKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 867
K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 137 AKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 178
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 408 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 444
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 226 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 262
>gi|34740331 otoferlin isoform a [Homo sapiens]
Length = 1997
Score = 712 bits (1839), Expect = 0.0
Identities = 410/1077 (38%), Positives = 584/1077 (54%), Gaps = 169/1077 (15%)
Query: 1140 PTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTW 1199
P +S ++ + LR +MYQAR L A D SDP+A V F++QSQ T V+ TL PTW
Sbjct: 948 PPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTW 1007
Query: 1200 DQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERM------- 1252
DQ L+F +E++GE + + PP IV+E+YD D+ G +FMGR +P ++
Sbjct: 1008 DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPP 1067
Query: 1253 ---PRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESEDTDLPY 1309
P+L ++ + RG+ +G+LLA+FEL+Q + + DLP
Sbjct: 1068 RFPPQLEYYQIYRGNATAGDLLAAFELLQ--------------------IGPAGKADLPP 1107
Query: 1310 ---PPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGGQTV 1366
P I VP I+P L + +E+L WGLR++K LA + P + +EC G+ V
Sbjct: 1108 INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGV 1167
Query: 1367 QSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIRSLE 1426
QS +I N +KNPNF+ + EV LP EL PP+ ++V+D R FGR +VG + SL
Sbjct: 1168 QSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLR 1227
Query: 1427 SFLCDPYSAESPS--------------PQGGPDDVSL---------------------LS 1451
F+ P +PS GG S L
Sbjct: 1228 RFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLD 1287
Query: 1452 PGEDVLIDID---------------DKEPLIPIQEEEFIDWWSKFFASIG-------ERE 1489
+ ++ +D +EP +E +DWWSK+FASI ++E
Sbjct: 1288 ATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQE 1347
Query: 1490 KCGSYLEKD------------------------------------------------FDT 1501
G LE+ D
Sbjct: 1348 PSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDE 1407
Query: 1502 LKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEE----TEDPSVIGEFKGLFKIY--PLP 1555
LKVY +LE+ F+ D+ +TF L RGKT ++ TE+ ++G FKG +Y PLP
Sbjct: 1408 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 1465
Query: 1556 EDPA----IPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKS 1611
ED + F + + P LVR+Y+VRA L P D NGK DPYI I +GK
Sbjct: 1466 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 1525
Query: 1612 VSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLL 1671
+ D++NYI L PVFGK F++ + P+E L + +YD+DL+ D+ IGET +DLENR
Sbjct: 1526 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 1585
Query: 1672 SKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTD-RVMFQDKEYS- 1729
SK A CG+ QTY G N WRD ++PSQ+L C+ +V P + RV ++ ++
Sbjct: 1586 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 1645
Query: 1730 IEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYSPLQPDIEQG 1781
EIE N P +E +AL L+ LVPEHVE+RPL +P +P IEQG
Sbjct: 1646 PSEIED---ENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQG 1702
Query: 1782 KLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVIL-DDLSLTGEKMSDIYV 1840
+L++WVD+FP + PG P +I+PR+ +++ LR IIWNT +V+L DD TGEK SDI+V
Sbjct: 1703 RLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFV 1762
Query: 1841 KGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTES 1900
+GW+ G +E KQ TDVHY SL GEGNFNWR++FPFDYL AE+ I+KK++ + D+TE
Sbjct: 1763 RGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEY 1822
Query: 1901 KIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEWFVSLF 1960
KIPAR+ QIWD D FS DDFLG+++LDLNR P+ AKTAK+C+++ VS+F
Sbjct: 1823 KIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVP-LVSIF 1881
Query: 1961 EQKTVKGWWPCVA-EEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPR 2019
+QK VKGWWP +A E ++ L GK+E L ++ E E+ P G R+EP+ LE P
Sbjct: 1882 KQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPD---PLEKPN 1938
Query: 2020 RPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLV 2076
RPDTSF+WF +P K+ ++ LW +RW ++ ++L +LLL LA+F+Y+ P Y K++
Sbjct: 1939 RPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKIL 1995
Score = 382 bits (980), Expect = e-105
Identities = 289/943 (30%), Positives = 458/943 (48%), Gaps = 131/943 (13%)
Query: 21 DAYCSAVFAGVKKRTKVIKNSVNPV-WNEGFEWDLKGIPLDQGSELHVVVKDHETMGRNR 79
D F G ++V++N + ++E F W + +D+ L + V ++ + N+
Sbjct: 18 DRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVAS-SIDRNEMLEIQVFNYSKVFSNK 76
Query: 80 FLGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPPPTPL 139
+G ++ L++V+ + + L+D SL ++V Y G V + L
Sbjct: 77 LIGTFRMVLQKVVEESHVEVTDT--LIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGDFL 134
Query: 140 -------------EPSPTLPDLDVVADTGGEEDTEDQGLTGDEAEPF---LDQSGGPGAP 183
E LP + GE+ G + A P P
Sbjct: 135 GDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEPQRP 194
Query: 184 TTPRKLPSRPPPHYP----------------------GIKRKRSAPTSRKLLS-DKPQDF 220
P L H + KRS P + S +P D+
Sbjct: 195 DEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPMDY 254
Query: 221 QIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSPGELFD 279
Q+ + VIE RQL G+N+ PVV V K T + + N P +NE F+ SP +FD
Sbjct: 255 QVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFD 314
Query: 280 EPIFITVVDSRSL-RTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYLK 338
+ I I+V+ S++L R+ L+G F+MDVGT+Y +P H + KW +LSDPDD S+G +GY+K
Sbjct: 315 KIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISSGLKGYVK 374
Query: 339 TSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGV--ALRGAHFCLKVFRAEDLPQMDD 396
+ V+G GD K D++DIE NLL P GV + A F +K++RAE LP+M+
Sbjct: 375 CDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNT 434
Query: 397 AVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMC 456
++M NVK+ F E+ K+LVDP+V+V FAG+ + + + + P WN+ + +FP +C
Sbjct: 435 SLMANVKKAFIGEN--KDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLC 492
Query: 457 EKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLDDYLGFL 515
++M+++I D D++ ND+ + T ++ + KIS G + GFL
Sbjct: 493 KRMKVQIRDSDKV--NDVAIGTHFIDLRKISNDGDK---------------------GFL 529
Query: 516 PTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQKVEDL 575
PT GP ++N+YGS R +T D + +LN G GEGV++R RLLL L ++V+ S +L
Sbjct: 530 PTLGPAWVNMYGSTRNYT-LLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSN---PEL 585
Query: 576 PADDILRVEKYL--------RRRKYSLFAAFYSATML--QDVDDAIQFEVSIGNYGNKFD 625
+ ++VE+ + ++ LF AF A+M+ ++ D I FEV+IGNYGN+ D
Sbjct: 586 TSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEVD 645
Query: 626 MTCLP---------------------------------LASTTQYSRAVFDGCHYYYLPW 652
P S+T R +Y++LP+
Sbjct: 646 GLSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLPY 705
Query: 653 GNVKPVVVLSSYWEDISHRIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQL 712
KP + + S+W D R+ N + IAD+LE GL + +K + S + + +
Sbjct: 706 LERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYP--ERRLRGV 763
Query: 713 TDELIAGCSQ--PLGDIHETPSA-THLDQYLYQLRTHHLSQITEAA--LALKLGHSELPA 767
+EL GC + L D + S+ T LD+ + L + + A L ++ +
Sbjct: 764 LEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRD 823
Query: 768 ALEQAEDWLLRLRALAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKN 827
L +++L +LR LA+EPQ+S+PDI IWM+ +KRVAY RVP+ +LFS GK+
Sbjct: 824 KLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS-IVEEETGKD 882
Query: 828 CGKLQTIFLKYPMEKVPG-ARMPVQIRVK--LWFGLSVDEKEF 867
C K++T+FLK P ++ G A VQ +V+ LW GLS KEF
Sbjct: 883 CAKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEF 925
Score = 35.4 bits (80), Expect = 0.59
Identities = 15/31 (48%), Positives = 19/31 (61%)
Query: 18 DISDAYCSAVFAGVKKRTKVIKNSVNPVWNE 48
D+ D Y FAG K +T V K+S P+WNE
Sbjct: 450 DLVDPYVQVFFAGQKGKTSVQKSSYEPLWNE 480
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/37 (35%), Positives = 21/37 (56%)
Query: 408 FESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 444
F ++ L DPF V F + C+++L +T P W+Q
Sbjct: 973 FAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQ 1009
Score = 32.3 bits (72), Expect = 5.0
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 1174 DPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1208
DPY V F Q KT V K++ P W++ ++F ++
Sbjct: 453 DPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDL 487
>gi|119120884 fer-1-like 6 [Homo sapiens]
Length = 1857
Score = 709 bits (1830), Expect = 0.0
Identities = 405/1085 (37%), Positives = 580/1085 (53%), Gaps = 172/1085 (15%)
Query: 1130 VSTLSFGVNRPTISCIFDYGNRYHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTV 1189
+S+ G N P + ++ + + LR +MYQAR L A D + SDP+A V+FL Q T
Sbjct: 804 MSSKGAGTNHPPSNLLYQEQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSHCQTTK 863
Query: 1190 VVKNTLNPTWDQTLIFYEIEIFGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSL 1249
++ TL+PTW+Q L+F ++ + G+ +AE PP +VVELYD D G E++G + P +
Sbjct: 864 IISQTLSPTWNQMLLFNDLVLHGDVKELAESPPLVVVELYDSDAVGKPEYLGATVAAPVV 923
Query: 1250 E------RMPRLAWFPLTRGSQPSGELLASFELIQREKPAIHHIPGFEVQETSRILDESE 1303
+ PRL + P+ G+ G+LLA FEL+Q + +P
Sbjct: 924 KLADQDYEPPRLCYHPIFCGNLSGGDLLAVFELLQVPPSGLQGLP--------------- 968
Query: 1304 DTDLPYPPPQREANIYMVPQNIKPALQRTAIEILAWGLRNMKSYQLANISSPSLVVECGG 1363
P PP IY VP NI+P L + +E+L WG+R MK QL ++ P ++ECGG
Sbjct: 969 ----PVEPPDI-TQIYPVPANIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQALIECGG 1023
Query: 1364 QTVQSCVIRNLRKNPNFDICTLFMEVMLPREELYCPPITVKVIDNRQFGRRPVVGQCTIR 1423
Q V+SCVI++ + NPNF I EV LP EL PP+++ V+D R FGR +VG TI
Sbjct: 1024 QGVKSCVIQSYKNNPNFSIQADAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTIN 1083
Query: 1424 SLESFLC--------------------------------------DP-----YSAESPSP 1440
L+ FLC DP Y P P
Sbjct: 1084 YLKQFLCKLREPLAPITQVDGTQPGHDISDSLTATESSGAHSSSQDPPADHIYVDVEPPP 1143
Query: 1441 QGGPDDVSLLSPGEDVLIDIDDKEPLI-----PIQEE----------------------- 1472
PD +L+D+ D P++ P+ +E
Sbjct: 1144 TVVPDSAQAQPA---ILVDVPDSSPMLEPEHTPVAQEPPKDGKPKDPRKPSRRSTKRRKR 1200
Query: 1473 --------EFIDWWSKFFASI-------------------------------GEREKCGS 1493
IDWWSK++AS+ G ++K
Sbjct: 1201 TIADESAENVIDWWSKYYASLKKAQKAKERNPKGKKGNTEAKPDEVVVDIEDGPKKKKDK 1260
Query: 1494 YLEK--------DFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEET---EDPSVI 1542
L+K + L++YD LE+ F D+ TF+L+RGK+ E+ + VI
Sbjct: 1261 MLKKKPKDDGIPNLAILQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDGDRVI 1318
Query: 1543 GEFKGLFKIYPLPEDPAIPMPPRQFHQ--LAAQGPQECLVRIYIVRAFGLQPKDPNGKCD 1600
G+FKG F IY P+D + + Q + P L+R+YIV AF L P DP+GK D
Sbjct: 1319 GKFKGSFCIYKSPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGKSD 1378
Query: 1601 PYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIG 1660
PYI I +GK + D+D YIP L PVFG+ FE+ T P E L I +YD+D++ D+ IG
Sbjct: 1379 PYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDLIG 1438
Query: 1661 ETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDR 1720
ET +DLENR SK A CGL Y + G N WRD +P+++L C+ +++ P + +
Sbjct: 1439 ETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFHPGK 1498
Query: 1721 VMFQDKEYSIEEIEAGRIPNPHLGPVEERLALHVLQQQG--------LVPEHVESRPLYS 1772
+ ++ +S + I + + E LAL VL LVPEH+E+RPLY
Sbjct: 1499 IQIGNQVFSGKTIFTEEDTDETVESYEH-LALKVLHSWEDIPEVGCRLVPEHIETRPLYH 1557
Query: 1773 PLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWNTRDVILDDLSL-T 1831
+P +EQG+LQMWVD+FPK + +PGPP +I+PRR + + LR IWNT DVIL+D ++ T
Sbjct: 1558 KDKPGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKGYELRVTIWNTEDVILEDENIFT 1617
Query: 1832 GEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLPAEQVCTIAKKDA 1891
G+K SDIYVKGW+ G E+ KQ+TDVHY SL GEGNFNWRF+FPF YLPAE+ I K++
Sbjct: 1618 GQKSSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVITKREN 1677
Query: 1892 FWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTAKKCSLDQLDDAF 1951
+ L+K E K PA +V Q+WD ++ S DDFLG+L+++LN P+ AK+AK C L + ++A
Sbjct: 1678 IFSLEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRAAKSAKACDLAKFENA- 1736
Query: 1952 HPEWFVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNM 2011
E +S+F+QK V+GWWP + K L GK+E +V E E+ P G+ R EP
Sbjct: 1737 SEETKISIFQQKRVRGWWPF----SKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPE- 1791
Query: 2012 NPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYA 2071
L P RPDTSF WF SP+K + +++W+ ++ II+ IL IL++FL +FIY P
Sbjct: 1792 --PLAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIAFILIILIIFLVLFIYTLPGAI 1849
Query: 2072 AMKLV 2076
+ ++V
Sbjct: 1850 SRRIV 1854
Score = 343 bits (879), Expect = 1e-93
Identities = 235/738 (31%), Positives = 373/738 (50%), Gaps = 126/738 (17%)
Query: 216 KPQDFQIRVQVIEGRQLPGVNIKPVVKVTAAGQTKRTRIHKG-NSPLFNETLFFNLFDSP 274
+ Q++QI + + E RQL G NI PVV + + K++ + +G NSP +NE F+
Sbjct: 79 RSQNYQIAITITEARQLVGENIDPVVTIEIGDEKKQSTVKEGTNSPFYNEYFVFDFIGPQ 138
Query: 275 GELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGAR 334
LFD+ I I+V + + + L+G F++D+GT+Y +P H + KW LL+DP D G +
Sbjct: 139 VHLFDKIIKISVFHHKLIGS-VLIGSFKVDLGTVYNQPGHQFCNKWALLTDPGDIRTGTK 197
Query: 335 GYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALR--GAHFCLKVFRAEDLP 392
GYLK + V+G GD K S+ +E IE NLL P G L A F +++++AE LP
Sbjct: 198 GYLKCDISVMGKGDVLKTSPK-TSDTEEPIEKNLLIPNGFPLERPWARFYVRLYKAEGLP 256
Query: 393 QMDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMF 452
+M+ ++M NV + F + K+LVDPFVEVSFAG+M + + + A+P W++ + MF
Sbjct: 257 KMNSSIMANVTK--AFVGDSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEMF 314
Query: 453 PSMCEKMRIRIIDWDRLTHNDI-VATTYLSMSKISAPGGEIEEEPAGAVKPSKASDLDDY 511
P +C +++I++ WD + ND+ +AT ++ + KIS ++ D
Sbjct: 315 PPLCRRVKIQV--WDEGSMNDVALATHFIDLKKIS-------------------NEQDGD 353
Query: 512 LGFLPTFGPCYINLYGSPREFTGFPDPYTELNTGKGEGVAYRGRLLLSLETKLVEHSEQ- 570
GFLPTFGP +INLYGSPR + D Y E+N G GEGV++RGR+L+ + +++ Q
Sbjct: 354 KGFLPTFGPAWINLYGSPRNHS-LMDDYQEMNEGFGEGVSFRGRILVEIAVEILSGRAQE 412
Query: 571 -------KVEDLPADD------------------------------ILRVEKY------- 586
K LP+ D + VE +
Sbjct: 413 SKFSKALKELKLPSKDKDSKSSKGKDKADKTEDGKSQQASNKTNSTEVEVESFDVPPEIV 472
Query: 587 -LRRRKYSLFAAFYSATMLQDV--DDAIQFEVSIGNYGNKFD------------------ 625
+ ++ LF AF+ ATM+ D I FEVSIGN+GN D
Sbjct: 473 PEKNEEFLLFGAFFEATMIDRKIGDKPISFEVSIGNFGNLIDGGSHHGSKKSAESAEEDL 532
Query: 626 -------------MTCLPLASTTQYSRAVF--DGCHYYYLPWGNVKPVVVLSSYWEDISH 670
+P+ASTT + + +Y YLP+ KP V S W D +
Sbjct: 533 LPLLHEGQGDVAHDVPIPMASTTHPEKPLVTEGNRNYNYLPFEAKKPCVYFISSWGDQTF 592
Query: 671 RIETQNQLLGIADRLEAGLEQVHLALKAQCSTEDVDSLVAQLTDELIAGCSQPLGDIHET 730
R+ N L +AD LE +E+V +K S E + + + + I+ S + + +
Sbjct: 593 RLHWSNMLEKMADFLEESIEEVRELIK--ISQEAPEEKMKTVLSDFISRSSAFISEAEKK 650
Query: 731 P---SATHLDQYLYQLRTHHLSQITEAALAL------KLGHSELPAALEQAEDWLLRLRA 781
P + T LD+ L L + + A + KL E+ + +A++++ ++R
Sbjct: 651 PKMLNQTTLDKKRLTLCWQELEAMCKEAKGIIQQQKKKLSVDEM---IHEAQNFVEKIRF 707
Query: 782 LAEEPQNSLPDIVIWMLQGDKRVAYQRVPAHQVLFSRRGANYCGKNCGKLQTIFLKYPME 841
L +EPQ+++PD+ IWML ++RVAY R+ + +L+S A GK+CGK++T FLK P +
Sbjct: 708 LVDEPQHTIPDVFIWMLSNNRRVAYARIASKDLLYS-PVAGQMGKHCGKIKTHFLKPPGK 766
Query: 842 KVPGARMPVQIRVKLWFG 859
+ G + ++ V LW G
Sbjct: 767 RPAGWSVQAKVDVYLWLG 784
Score = 41.2 bits (95), Expect = 0.011
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 1 MLRVFILYAENVHTPDTD-ISDAYCSAVFAG--VKKRTKVIKNSVNPVWNEGFEWDLKGI 57
++RV+I+ A N+ D D SD Y +K R K I +NPV+ FE
Sbjct: 1357 LIRVYIVAAFNLSPADPDGKSDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQAT-- 1414
Query: 58 PLDQGSELHVVVKDHETMGRNRFLGEAKVPL 88
+ S L +++ DH+ +G + +GE K+ L
Sbjct: 1415 -FPKESLLSILIYDHDMIGTDDLIGETKIDL 1444
Score = 35.8 bits (81), Expect = 0.45
Identities = 16/41 (39%), Positives = 22/41 (53%)
Query: 1168 DKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEI 1208
D DP+ VSF Q +T V KN +P W + +IF E+
Sbjct: 273 DSKDLVDPFVEVSFAGQMGRTTVQKNCADPVWHEQVIFKEM 313
Score = 33.5 bits (75), Expect = 2.2
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 410 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQ 444
++ L DPF +V+F +KI+ +T +P WNQ
Sbjct: 841 ADSNGLSDPFAKVTFLSHCQTTKIISQTLSPTWNQ 875
Score = 32.0 bits (71), Expect = 6.5
Identities = 14/31 (45%), Positives = 18/31 (58%)
Query: 18 DISDAYCSAVFAGVKKRTKVIKNSVNPVWNE 48
D+ D + FAG RT V KN +PVW+E
Sbjct: 276 DLVDPFVEVSFAGQMGRTTVQKNCADPVWHE 306
>gi|4759026 RAS protein activator like 1 [Homo sapiens]
Length = 804
Score = 65.5 bits (158), Expect = 5e-10
Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 13/127 (10%)
Query: 1154 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1213
LRC++ ARDLA D SDP+A V + QS +T +K T P WD+ L E
Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVL---------E 185
Query: 1214 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQP-SLERMPRLAWF---PLTRGSQPSGE 1269
+ P + VEL+D D G ++F+G P +L++ P WF P R + SG
Sbjct: 186 LREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAEEDSGG 245
Query: 1270 LLASFEL 1276
L + +
Sbjct: 246 NLGALRV 252
Score = 43.9 bits (102), Expect = 0.002
Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 13/167 (7%)
Query: 1494 YLEKDFDTLKVYDTQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYP 1553
+L DF L Y + V G D L R + T DP I + L ++ P
Sbjct: 60 HLPLDFHQLAFYVLDEDTV----GHDDIIGKISLSR---EAITADPRGIDSWINLSRVDP 112
Query: 1554 LPEDPAIPMPPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVS 1613
D + Q+ G CL R +++ A L P+D +G DP+ ++ G +S+
Sbjct: 113 ---DAEVQGEICLSVQMLEDGQGRCL-RCHVLHARDLAPRDISGTSDPFARVFWGSQSL- 167
Query: 1614 DQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIG 1660
+ + I T P + ++ EL L++ L+D+D++ K++ +G
Sbjct: 168 -ETSTIKKTRFPHWDEVLELREMPGAPSPLRVELWDWDMVGKNDFLG 213
Score = 43.5 bits (101), Expect = 0.002
Identities = 59/268 (22%), Positives = 100/268 (37%), Gaps = 64/268 (23%)
Query: 222 IRVQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPG 275
+ V+V+EGR LP ++ +VKV + + + P + E +L
Sbjct: 7 LNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHL----- 61
Query: 276 ELFDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLS--DPDDFSAGA 333
L + V+D ++ D ++G+ + I +PR + W+ LS DPD A
Sbjct: 62 PLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRG--IDSWINLSRVDPD---AEV 116
Query: 334 RGYLKTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQ 393
+G + S+ +L ED + LR V A DL
Sbjct: 117 QGEICLSVQML-----------------EDGQGRCLR------------CHVLHARDLAP 147
Query: 394 MDDAVMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFP 453
D + DPF V + + L + ++KT P W++ + L M P
Sbjct: 148 RDIS----------------GTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREM-P 190
Query: 454 SMCEKMRIRIIDWDRLTHNDIVATTYLS 481
+R+ + DWD + ND + S
Sbjct: 191 GAPSPLRVELWDWDMVGKNDFLGMVEFS 218
Score = 33.9 bits (76), Expect = 1.7
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 2 LRVFILYAENVHTPD-TDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEW-DLKGIPL 59
LR +L+A ++ D + SD + + T IK + P W+E E ++ G P
Sbjct: 135 LRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGAP- 193
Query: 60 DQGSELHVVVKDHETMGRNRFLG 82
S L V + D + +G+N FLG
Sbjct: 194 ---SPLRVELWDWDMVGKNDFLG 213
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 54.3 bits (129), Expect = 1e-06
Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)
Query: 1127 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1171
S SVS G ++PT + +D GN L ++ QAR+L D +
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726
Query: 1172 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1217
+SDP+ V L + +VV+N +LNP W+QT+I+ I +
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780
Query: 1218 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1271
+ ++ V ++D+D + +++F+G + S L+ PR W+PL ++ G+
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838
Query: 1272 ASFELIQREKPAI 1284
+S Q KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)
Query: 1582 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1629
I+I++A L P+D NG DP++K+ + G+ V N ++ +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770
Query: 1630 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1668
++ +K L++T++DYD S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812
Score = 39.3 bits (90), Expect = 0.041
Identities = 40/130 (30%), Positives = 57/130 (43%), Gaps = 21/130 (16%)
Query: 29 AGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKV 86
A K+RTK ++ S+NP WN+ + K I ++Q L V V D++ N FLGE +
Sbjct: 4751 AEYKRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLI 4808
Query: 87 PLREVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPP 135
L S S N P K+ T G S Q S +P P + +FP
Sbjct: 4809 DL------SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPD 4862
Query: 136 PTPLEPSPTL 145
P+ PT+
Sbjct: 4863 PSKDMQVPTI 4872
Score = 36.6 bits (83), Expect = 0.26
Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Query: 431 SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 486
+K ++K+ NP+WNQ + ++ +K + + + D+DR + ND + + +S S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814
Score = 32.0 bits (71), Expect = 6.5
Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 12/123 (9%)
Query: 111 QPTGASLVLQVSYTPLPGAV--PLFPPPTPLEPSPTL-PDLDVVADTGGEEDTEDQGLTG 167
QP+G + L PG V P+ PP T P+ L P TG E+ + +Q
Sbjct: 334 QPSGLTKPLAQQ----PGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 168 DEAEP-----FLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQI 222
A+P Q GP P T + +P PG++ AP K +P +I
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 223 RVQ 225
Q
Sbjct: 450 PAQ 452
Score = 32.0 bits (71), Expect = 6.5
Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 39/160 (24%)
Query: 81 LGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPP----- 135
LG AK P ++ T S S P QP G V TP P PP
Sbjct: 366 LGPAKPPAQQ---TGSEKPSSEQPGPKALAQPPG------VGKTPAQQPGPAKPPTQQVG 416
Query: 136 -PTPLE-----------PSPTLPDLD------VVADTGGEEDTEDQGLTGDEAEPFLDQS 177
P PL P PT + + A G T Q TG P Q
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ-TGPTKPP--SQL 473
Query: 178 GGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKP 217
GP P + P++PPP PG + P S++ S KP
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPG----SAKPPSQQPGSTKP 509
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 54.3 bits (129), Expect = 1e-06
Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 46/193 (23%)
Query: 1127 SMSVSTLSFGVNRPT---------------ISCIFDYGNRYHLRCYMYQARDLAAMDKDS 1171
S SVS G ++PT + +D GN L ++ QAR+L D +
Sbjct: 4670 SPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGN---LIIHILQARNLVPRDNNG 4726
Query: 1172 FSDPYAIVSFLHQSQKTVVVKN--------------TLNPTWDQTLIFYEIEIFGEPATV 1217
+SDP+ V L + +VV+N +LNP W+QT+I+ I +
Sbjct: 4727 YSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISM------E 4780
Query: 1218 AEQPPSIVVELYDHDTYGADEFMGRCICQPS----LERMPRLAWFPLTRGSQ--PSGELL 1271
+ ++ V ++D+D + +++F+G + S L+ PR W+PL ++ G+
Sbjct: 4781 QLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPR--WYPLKEQTESIDHGKSH 4838
Query: 1272 ASFELIQREKPAI 1284
+S Q KP++
Sbjct: 4839 SSQSSQQSPKPSV 4851
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 15/102 (14%)
Query: 1582 IYIVRAFGLQPKDPNGKCDPYIKISI--GKKSVSDQDN----------YIPCTLEPVFGK 1629
I+I++A L P+D NG DP++K+ + G+ V N ++ +L P + +
Sbjct: 4711 IHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQ 4770
Query: 1630 MF---ELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1668
++ +K L++T++DYD S ++ +GE ++DL +
Sbjct: 4771 TVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSS 4812
Score = 39.3 bits (90), Expect = 0.041
Identities = 40/130 (30%), Positives = 57/130 (43%), Gaps = 21/130 (16%)
Query: 29 AGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQ--GSELHVVVKDHETMGRNRFLGEAKV 86
A K+RTK ++ S+NP WN+ + K I ++Q L V V D++ N FLGE +
Sbjct: 4751 AEYKRRTKHVQKSLNPEWNQTVIY--KSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLI 4808
Query: 87 PLREVLATPSLSASFNAPLLDTKKQPT-----GASLVLQVS-YTPLPGAVP-----LFPP 135
L S S N P K+ T G S Q S +P P + +FP
Sbjct: 4809 DL------SSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPD 4862
Query: 136 PTPLEPSPTL 145
P+ PT+
Sbjct: 4863 PSKDMQVPTI 4872
Score = 36.6 bits (83), Expect = 0.26
Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Query: 431 SKILEKTANPQWNQNITLPAMFPSMCEK--MRIRIIDWDRLTHNDIVATTYLSMSKIS 486
+K ++K+ NP+WNQ + ++ +K + + + D+DR + ND + + +S S
Sbjct: 4757 TKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS 4814
Score = 32.0 bits (71), Expect = 6.5
Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 12/123 (9%)
Query: 111 QPTGASLVLQVSYTPLPGAV--PLFPPPTPLEPSPTL-PDLDVVADTGGEEDTEDQGLTG 167
QP+G + L PG V P+ PP T P+ L P TG E+ + +Q
Sbjct: 334 QPSGLTKPLAQQ----PGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 168 DEAEP-----FLDQSGGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKPQDFQI 222
A+P Q GP P T + +P PG++ AP K +P +I
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 223 RVQ 225
Q
Sbjct: 450 PAQ 452
Score = 32.0 bits (71), Expect = 6.5
Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 39/160 (24%)
Query: 81 LGEAKVPLREVLATPSLSASFNAPLLDTKKQPTGASLVLQVSYTPLPGAVPLFPP----- 135
LG AK P ++ T S S P QP G V TP P PP
Sbjct: 366 LGPAKPPAQQ---TGSEKPSSEQPGPKALAQPPG------VGKTPAQQPGPAKPPTQQVG 416
Query: 136 -PTPLE-----------PSPTLPDLD------VVADTGGEEDTEDQGLTGDEAEPFLDQS 177
P PL P PT + + A G T Q TG P Q
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ-TGPTKPP--SQL 473
Query: 178 GGPGAPTTPRKLPSRPPPHYPGIKRKRSAPTSRKLLSDKP 217
GP P + P++PPP PG + P S++ S KP
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPG----SAKPPSQQPGSTKP 509
>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
sapiens]
Length = 778
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)
Query: 1158 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1217
+ + RDL AMD + SDPY HQ K+ ++ TLNP W + F+ E
Sbjct: 255 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 306
Query: 1218 AEQPPSIVVELYDHDTYGADEFMGRC 1243
E+ I + +D D D+F+GRC
Sbjct: 307 -ERGGVIDITAWDKDAGKRDDFIGRC 331
Score = 42.7 bits (99), Expect = 0.004
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 1579 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1638
+V I ++ L+ D NG DPY+K +G + + +P TL P + + F+
Sbjct: 250 IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 307
Query: 1639 LEKDLKITLYDYDLLSKDEKIGETVVDL 1666
+ IT +D D +D+ IG VDL
Sbjct: 308 RGGVIDITAWDKDAGKRDDFIGRCQVDL 335
Score = 41.2 bits (95), Expect = 0.011
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 1582 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1639
I + R L +D G DPY+K IG K V + I L PV+ E C L L
Sbjct: 44 ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 99
Query: 1640 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1673
+ L I ++DYD +D+ +G +DL L++
Sbjct: 100 REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 133
Score = 40.8 bits (94), Expect = 0.014
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
Query: 2 LRVFILYAENVHTPD-TDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
L+V ++ AE + D T SD +C + T + ++NP WN+ F +++K D
Sbjct: 407 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----D 462
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
S L V V D + FLG+ +PL +
Sbjct: 463 IHSVLEVTVYDEDRDRSADFLGKVAIPLLSI 493
Score = 38.9 bits (89), Expect = 0.053
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)
Query: 1563 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1622
P R FH L G +++ ++RA GL D GK DP+ + + + Y
Sbjct: 394 PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 447
Query: 1623 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1666
L P + K+F + L++T+YD D + +G+ + L
Sbjct: 448 LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 490
Score = 37.7 bits (86), Expect = 0.12
Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 417 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 475
DP+V+ GK + SKI+ K NP W + + + + E + I++ D+D +D +
Sbjct: 62 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 119
Query: 476 ATTYLSMSKI 485
+ +L ++++
Sbjct: 120 GSAFLDLTQL 129
Score = 35.0 bits (79), Expect = 0.77
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 19 ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRN 78
+SD Y K ++K++ ++NP W E F++ L ++G + + D + R+
Sbjct: 269 LSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGVIDITAWDKDAGKRD 325
Query: 79 RFLGEAKVPL 88
F+G +V L
Sbjct: 326 DFIGRCQVDL 335
Score = 35.0 bits (79), Expect = 0.77
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)
Query: 1154 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1213
L+ + +A L A D SDP+ +V + T V LNP W++ F
Sbjct: 407 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 458
Query: 1214 PATVAEQPPSIVVELYDHDTYGADEFMGR 1242
+ + + V +YD D + +F+G+
Sbjct: 459 --NIKDIHSVLEVTVYDEDRDRSADFLGK 485
Score = 34.3 bits (77), Expect = 1.3
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 1152 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1208
Y L + + + LAA D+ SDPY V F + ++ ++ LNP W++ +
Sbjct: 40 YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 96
Query: 1209 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1241
+ EP + ++++D+D D+FMG
Sbjct: 97 DHLREP---------LYIKVFDYDFGLQDDFMG 120
Score = 32.0 bits (71), Expect = 6.5
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 411 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 470
+ L DP+V+ + SKI+ KT NPQW + ++ + I D D
Sbjct: 265 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 323
Query: 471 HNDIVATTYLSMSKIS 486
+D + + +S +S
Sbjct: 324 RDDFIGRCQVDLSALS 339
>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
sapiens]
Length = 999
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)
Query: 1158 MYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATV 1217
+ + RDL AMD + SDPY HQ K+ ++ TLNP W + F+ E
Sbjct: 476 LIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE-------- 527
Query: 1218 AEQPPSIVVELYDHDTYGADEFMGRC 1243
E+ I + +D D D+F+GRC
Sbjct: 528 -ERGGVIDITAWDKDAGKRDDFIGRC 552
Score = 42.7 bits (99), Expect = 0.004
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 1579 LVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLP 1638
+V I ++ L+ D NG DPY+K +G + + +P TL P + + F+
Sbjct: 471 IVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKY--KSKIMPKTLNPQWREQFDFHLYEE 528
Query: 1639 LEKDLKITLYDYDLLSKDEKIGETVVDL 1666
+ IT +D D +D+ IG VDL
Sbjct: 529 RGGVIDITAWDKDAGKRDDFIGRCQVDL 556
Score = 41.2 bits (95), Expect = 0.011
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 1582 IYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTL--PL 1639
I + R L +D G DPY+K IG K V + I L PV+ E C L L
Sbjct: 265 ITLRRGQSLAARDRGGTSDPYVKFKIGGKEVF-RSKIIHKNLNPVWE---EKACILVDHL 320
Query: 1640 EKDLKITLYDYDLLSKDEKIGETVVDLENRLLSK 1673
+ L I ++DYD +D+ +G +DL L++
Sbjct: 321 REPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNR 354
Score = 40.8 bits (94), Expect = 0.014
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
Query: 2 LRVFILYAENVHTPD-TDISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
L+V ++ AE + D T SD +C + T + ++NP WN+ F +++K D
Sbjct: 628 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIK----D 683
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
S L V V D + FLG+ +PL +
Sbjct: 684 IHSVLEVTVYDEDRDRSADFLGKVAIPLLSI 714
Score = 38.9 bits (89), Expect = 0.053
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%)
Query: 1563 PPRQFHQLAAQGPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCT 1622
P R FH L G +++ ++RA GL D GK DP+ + + + Y
Sbjct: 615 PLRIFHNLKDVG----FLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVY--KN 668
Query: 1623 LEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDL 1666
L P + K+F + L++T+YD D + +G+ + L
Sbjct: 669 LNPEWNKVFTFNIK-DIHSVLEVTVYDEDRDRSADFLGKVAIPL 711
Score = 37.7 bits (86), Expect = 0.12
Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 417 DPFVEVSFAGK-MLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLTHNDIV 475
DP+V+ GK + SKI+ K NP W + + + + E + I++ D+D +D +
Sbjct: 283 DPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACI--LVDHLREPLYIKVFDYDFGLQDDFM 340
Query: 476 ATTYLSMSKI 485
+ +L ++++
Sbjct: 341 GSAFLDLTQL 350
Score = 35.0 bits (79), Expect = 0.77
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 19 ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLDQGSELHVVVKDHETMGRN 78
+SD Y K ++K++ ++NP W E F++ L ++G + + D + R+
Sbjct: 490 LSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYE---ERGGVIDITAWDKDAGKRD 546
Query: 79 RFLGEAKVPL 88
F+G +V L
Sbjct: 547 DFIGRCQVDL 556
Score = 35.0 bits (79), Expect = 0.77
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 10/89 (11%)
Query: 1154 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1213
L+ + +A L A D SDP+ +V + T V LNP W++ F
Sbjct: 628 LQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF-------- 679
Query: 1214 PATVAEQPPSIVVELYDHDTYGADEFMGR 1242
+ + + V +YD D + +F+G+
Sbjct: 680 --NIKDIHSVLEVTVYDEDRDRSADFLGK 706
Score = 34.3 bits (77), Expect = 1.3
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 1152 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFL---HQSQKTVVVKNTLNPTWDQTLIFYEI 1208
Y L + + + LAA D+ SDPY V F + ++ ++ LNP W++ +
Sbjct: 261 YQLDITLRRGQSLAARDRGGTSDPY--VKFKIGGKEVFRSKIIHKNLNPVWEEKACIL-V 317
Query: 1209 EIFGEPATVAEQPPSIVVELYDHDTYGADEFMG 1241
+ EP + ++++D+D D+FMG
Sbjct: 318 DHLREP---------LYIKVFDYDFGLQDDFMG 341
Score = 32.0 bits (71), Expect = 6.5
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 411 NKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRLT 470
+ L DP+V+ + SKI+ KT NPQW + ++ + I D D
Sbjct: 486 DSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDF-HLYEERGGVIDITAWDKDAGK 544
Query: 471 HNDIVATTYLSMSKIS 486
+D + + +S +S
Sbjct: 545 RDDFIGRCQVDLSALS 560
>gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 2 [Homo sapiens]
Length = 731
Score = 53.1 bits (126), Expect = 3e-06
Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 1154 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1213
LRC + +ARDLA D++ SDP+ V + ++++T +VK + P W++T +E E+ E
Sbjct: 63 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 118
Query: 1214 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1260
A A + VE +D D ++F+G+ + R+ + WF L
Sbjct: 119 GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 162
Score = 48.5 bits (114), Expect = 7e-05
Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 1574 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1633
G + C +R ++ A L PKD NG DP++++ K + + + + + P + + FE
Sbjct: 57 GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 114
Query: 1634 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1667
+ L + +D+DL+S+++ +G+ V+D++
Sbjct: 115 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 148
Score = 42.4 bits (98), Expect = 0.005
Identities = 31/136 (22%), Positives = 53/136 (38%), Gaps = 18/136 (13%)
Query: 350 APLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDAVMDNVKQIFGFE 409
A L DP E+ + E +L R V A DL D
Sbjct: 33 AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-------------- 77
Query: 410 SNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCEKMRIRIIDWDRL 469
+ DPFV V + G+ + I++K+ P+WN+ +M E + + DWD +
Sbjct: 78 --RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-EALCVEAWDWDLV 134
Query: 470 THNDIVATTYLSMSKI 485
+ ND + + + ++
Sbjct: 135 SRNDFLGKVVIDVQRL 150
Score = 41.6 bits (96), Expect = 0.008
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 4/91 (4%)
Query: 2 LRVFILYAENVHTPDTD-ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
LR +L A ++ D + SD + + G + T ++K S P WNE FE++L+ ++
Sbjct: 63 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 122
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
L V D + + RN FLG+ + ++ +
Sbjct: 123 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 150
>gi|239743307 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 1 [Homo sapiens]
Length = 757
Score = 53.1 bits (126), Expect = 3e-06
Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 1154 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGE 1213
LRC + +ARDLA D++ SDP+ V + ++++T +VK + P W++T +E E+ E
Sbjct: 135 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNET---FEFEL-QE 190
Query: 1214 PATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPRL--AWFPL 1260
A A + VE +D D ++F+G+ + R+ + WF L
Sbjct: 191 GAMEA-----LCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRL 234
Score = 48.5 bits (114), Expect = 7e-05
Identities = 24/94 (25%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 1574 GPQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFEL 1633
G + C +R ++ A L PKD NG DP++++ K + + + + + P + + FE
Sbjct: 129 GARACRLRCSVLEARDLAPKDRNGTSDPFVRVRY--KGRTRETSIVKKSCYPRWNETFEF 186
Query: 1634 TCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLE 1667
+ L + +D+DL+S+++ +G+ V+D++
Sbjct: 187 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQ 220
Score = 43.1 bits (100), Expect = 0.003
Identities = 53/268 (19%), Positives = 96/268 (35%), Gaps = 60/268 (22%)
Query: 224 VQVIEGRQLPGVNIKP------VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGEL 277
++++EG+ LP +I +VKV + + K P + E +L +
Sbjct: 9 IRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPT---- 64
Query: 278 FDEPIFITVVDSRSLRTDALLGEFRMDVGTIYREPRHAYLRKWLLLSDPDDFSAGARGYL 337
+ V+D +L D ++G+ + TI P+ G G+
Sbjct: 65 -FHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPK------------------GFSGW- 104
Query: 338 KTSLCVLGPGDEAPLERKDPSEDKEDIESNLLRPTGVALRGAHFCLKVFRAEDLPQMDDA 397
A L DP E+ + E +L R V A DL D
Sbjct: 105 ------------AHLTEVDPDEEVQG-EIHLRLEVWPGARACRLRCSVLEARDLAPKD-- 149
Query: 398 VMDNVKQIFGFESNKKNLVDPFVEVSFAGKMLCSKILEKTANPQWNQNITLPAMFPSMCE 457
+ DPFV V + G+ + I++K+ P+WN+ +M E
Sbjct: 150 --------------RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAM-E 194
Query: 458 KMRIRIIDWDRLTHNDIVATTYLSMSKI 485
+ + DWD ++ ND + + + ++
Sbjct: 195 ALCVEAWDWDLVSRNDFLGKVVIDVQRL 222
Score = 41.6 bits (96), Expect = 0.008
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 4/91 (4%)
Query: 2 LRVFILYAENVHTPDTD-ISDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDLKGIPLD 60
LR +L A ++ D + SD + + G + T ++K S P WNE FE++L+ ++
Sbjct: 135 LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAME 194
Query: 61 QGSELHVVVKDHETMGRNRFLGEAKVPLREV 91
L V D + + RN FLG+ + ++ +
Sbjct: 195 ---ALCVEAWDWDLVSRNDFLGKVVIDVQRL 222
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,320,868
Number of Sequences: 37866
Number of extensions: 4635425
Number of successful extensions: 16557
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 210
Number of HSP's that attempted gapping in prelim test: 14286
Number of HSP's gapped (non-prelim): 1724
length of query: 2080
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1962
effective length of database: 13,779,330
effective search space: 27035045460
effective search space used: 27035045460
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.