Guide to the Human Genome
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Name: OTOF Sequence: fasta or formatted (1307aa) NCBI GI: 35493853
Description:

otoferlin isoform c

Referenced in:

Auditory and Vestibular Functions
Additional Membrane Functions

Other entries for this name:
alt prot [1997aa] otoferlin isoform a
alt prot [1230aa] otoferlin isoform d
alt prot [1230aa] otoferlin isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9         77           2
 C cysteine            1.5         20           2
 D aspartate           6.7         88           3
 E glutamate           8.6        113           4
 F phenylalanine       4.2         55           2
 G glycine             6.4         84           2
 H histidine           1.8         24           1
 I isoleucine          4.3         56           2
 K lysine              7.4         97           6
 L leucine            10.5        137          11
 M methionine          2.4         31           2
 N asparagine          3.3         43           2
 P proline             6.4         83           2
 Q glutamine           3.4         44           2
 R arginine            6.2         81           2
 S serine              5.6         73           3
 T threonine           4.5         59           2
 V valine              6.2         81           3
 W tryptophan          1.9         25           2
 Y tyrosine            2.8         36           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   otoferlin isoform c 
OTOF                  0.965   otoferlin isoform a 
OTOF                  0.937   otoferlin isoform b 
OTOF                  0.924   otoferlin isoform d 
FER1L6                0.467   fer-1-like 6 
DYSF                  0.264   dysferlin isoform 1 
DYSF                  0.264   dysferlin isoform 5 
DYSF                  0.264   dysferlin isoform 6 
DYSF                  0.264   dysferlin isoform 14 
DYSF                  0.264   dysferlin isoform 11 
DYSF                  0.264   dysferlin isoform 10 
DYSF                  0.260   dysferlin isoform 2 
DYSF                  0.260   dysferlin isoform 8 
DYSF                  0.260   dysferlin isoform 3 
DYSF                  0.260   dysferlin isoform 4 
DYSF                  0.260   dysferlin isoform 7 
DYSF                  0.260   dysferlin isoform 13 
DYSF                  0.260   dysferlin isoform 12 
DYSF                  0.260   dysferlin isoform 9 
MYOF                  0.249   myoferlin isoform b 
MYOF                  0.249   myoferlin isoform a 
FER1L5                0.153   fer-1-like 5 isoform 1 
FER1L5                0.150   fer-1-like 5 isoform 2 
RASAL1                0.016   RAS protein activator like 1 
LOC100132214          0.011   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.011   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.011   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.011   PREDICTED: similar to calcium-promoted Ras inactiva...
RASA4                 0.011   RAS p21 protein activator 4 isoform 2 
RASA4                 0.011   RAS p21 protein activator 4 isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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