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Search of human proteins with 4503355
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
(1865 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens] 3733 0.0
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens] 2366 0.0
gi|31377468 dedicator of cytokinesis 2 [Homo sapiens] 2146 0.0
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens] 1201 0.0
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens] 1189 0.0
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] 77 1e-13
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens] 69 3e-11
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens] 65 6e-10
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens] 65 6e-10
gi|54112429 dedicator of cytokinesis 7 [Homo sapiens] 59 6e-08
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens] 58 8e-08
gi|56549694 enabled homolog isoform a [Homo sapiens] 56 3e-07
gi|39930375 enabled homolog isoform b [Homo sapiens] 56 3e-07
gi|33356148 formin-like 1 [Homo sapiens] 54 1e-06
gi|157426887 dedicator of cytokinesis 6 [Homo sapiens] 54 1e-06
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 54 2e-06
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 54 2e-06
gi|122937271 WAS protein homolog associated with actin, golgi me... 52 4e-06
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 52 5e-06
gi|149944526 additional sex combs like 3 [Homo sapiens] 51 9e-06
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 50 2e-05
gi|157168329 formin 1 [Homo sapiens] 50 3e-05
gi|61743948 abl-interactor 1 isoform d [Homo sapiens] 50 3e-05
gi|61743944 abl-interactor 1 isoform b [Homo sapiens] 50 3e-05
gi|18959210 WIRE protein [Homo sapiens] 50 3e-05
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 49 4e-05
gi|150417989 cyclin K isoform 1 [Homo sapiens] 49 4e-05
gi|160707881 formin 2 [Homo sapiens] 49 5e-05
gi|61743942 abl-interactor 1 isoform a [Homo sapiens] 49 5e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 49 5e-05
>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
Length = 1865
Score = 3733 bits (9680), Expect = 0.0
Identities = 1865/1865 (100%), Positives = 1865/1865 (100%)
Query: 1 MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIF 60
MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIF
Sbjct: 1 MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIF 60
Query: 61 PASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRH 120
PASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRH
Sbjct: 61 PASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRH 120
Query: 121 MIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTS 180
MIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTS
Sbjct: 121 MIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTS 180
Query: 181 TISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDA 240
TISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDA
Sbjct: 181 TISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDA 240
Query: 241 EVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQ 300
EVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQ
Sbjct: 241 EVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQ 300
Query: 301 IVRVGRMELRDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDF 360
IVRVGRMELRDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDF
Sbjct: 301 IVRVGRMELRDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDF 360
Query: 361 LQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIM 420
LQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIM
Sbjct: 361 LQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIM 420
Query: 421 PGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKS 480
PGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKS
Sbjct: 421 PGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKS 480
Query: 481 VIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYD 540
VIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYD
Sbjct: 481 VIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYD 540
Query: 541 GTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKD 600
GTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKD
Sbjct: 541 GTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKD 600
Query: 601 SFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFN 660
SFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFN
Sbjct: 601 SFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFN 660
Query: 661 IMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLK 720
IMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLK
Sbjct: 661 IMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLK 720
Query: 721 NYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSIN 780
NYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSIN
Sbjct: 721 NYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSIN 780
Query: 781 DMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYC 840
DMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYC
Sbjct: 781 DMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYC 840
Query: 841 LIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRKDVGPTQ 900
LIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRKDVGPTQ
Sbjct: 841 LIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRKDVGPTQ 900
Query: 901 RHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTD 960
RHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTD
Sbjct: 901 RHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTD 960
Query: 961 VVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQ 1020
VVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQ
Sbjct: 961 VVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQ 1020
Query: 1021 LWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKF 1080
LWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKF
Sbjct: 1021 LWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKF 1080
Query: 1081 IPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGR 1140
IPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGR
Sbjct: 1081 IPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGR 1140
Query: 1141 GDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCT 1200
GDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCT
Sbjct: 1141 GDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCT 1200
Query: 1201 VNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQ 1260
VNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQ
Sbjct: 1201 VNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQ 1260
Query: 1261 RDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKK 1320
RDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKK
Sbjct: 1261 RDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKK 1320
Query: 1321 QAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPN 1380
QAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPN
Sbjct: 1321 QAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPN 1380
Query: 1381 AEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYS 1440
AEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYS
Sbjct: 1381 AEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYS 1440
Query: 1441 RPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLT 1500
RPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLT
Sbjct: 1441 RPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLT 1500
Query: 1501 NDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEK 1560
NDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEK
Sbjct: 1501 NDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEK 1560
Query: 1561 IEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSS 1620
IEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSS
Sbjct: 1561 IEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSS 1620
Query: 1621 LDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKMHSR 1680
LDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKMHSR
Sbjct: 1621 LDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKMHSR 1680
Query: 1681 SQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQR 1740
SQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQR
Sbjct: 1681 SQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQR 1740
Query: 1741 PKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPP 1800
PKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPP
Sbjct: 1741 PKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPP 1800
Query: 1801 PLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKTTRKQTSVD 1860
PLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKTTRKQTSVD
Sbjct: 1801 PLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKTTRKQTSVD 1860
Query: 1861 SGIVQ 1865
SGIVQ
Sbjct: 1861 SGIVQ 1865
>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
Length = 1870
Score = 2366 bits (6131), Expect = 0.0
Identities = 1211/1912 (63%), Positives = 1475/1912 (77%), Gaps = 111/1912 (5%)
Query: 1 MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIF 60
M RW+PTKR+ KYGVA YNY+A ELSLQIGDTVHILE YEGWYRGYTL+ KSKKGIF
Sbjct: 1 MARWIPTKRQ-KYGVAIYNYNASQDVELSLQIGDTVHILEMYEGWYRGYTLQNKSKKGIF 59
Query: 61 PASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRH 120
P +YIHLKEA VE GQHETVIPG+LPL+QE+T+TLREW+ IWR+LYV + +FR ++
Sbjct: 60 PETYIHLKEATVEDLGQHETVIPGELPLVQELTSTLREWAVIWRKLYVNNKLTLFRQLQQ 119
Query: 121 MIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTS 180
M Y LIEWRSQILSGTLP+DEL ELKKKVTAKID+GNR+L LDLVVRD++GNILDP+ TS
Sbjct: 120 MTYSLIEWRSQILSGTLPKDELAELKKKVTAKIDHGNRMLGLDLVVRDDNGNILDPDETS 179
Query: 181 TISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDA 240
TI+LF+AHE+ASK++EE++QEEKS QN+D+ Q+ F+ + L+VN KN VC IGEDA
Sbjct: 180 TIALFKAHEVASKRIEEKIQEEKSILQNLDLRGQSIFSTIHTYGLYVNFKNFVCNIGEDA 239
Query: 241 EVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQ 300
E+ M+LYDP +S FISENYL+RW S+G+PK+I++L+NL+AVFTDL S DL R ++S VCQ
Sbjct: 240 ELFMALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQAVFTDLSSMDLIRPRVSLVCQ 299
Query: 301 IVRVGRMELRDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVA----- 355
IVRVG MEL++ +K T GLRRPFGVAVMD+TDII+GKVDDE+KQHFIPFQ +A
Sbjct: 300 IVRVGHMELKEG--KKHTCGLRRPFGVAVMDITDIIHGKVDDEEKQHFIPFQQIAMETYI 357
Query: 356 ----------------GENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEF 399
GEN+ L +V+NKVIAAKEVNHKGQGLWV+LKLLPGD+ Q++K F
Sbjct: 358 RQRQLIMSPLITSHVIGENEPLTSVLNKVIAAKEVNHKGQGLWVSLKLLPGDLTQVQKNF 417
Query: 400 PHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDG 459
HLVDR+TA+ARK GFPEII+PGDVRNDIYVTL+ G+FDKG K T KNVEVT+SV+DE+G
Sbjct: 418 SHLVDRSTAIARKMGFPEIILPGDVRNDIYVTLIHGEFDKGKKKTPKNVEVTMSVHDEEG 477
Query: 460 KRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQ 519
K LE I PGAG E ISEYKSV+YYQVKQP W+ETVKV+I IE+V R H+RFTFRHRSSQ
Sbjct: 478 KLLEKAIHPGAGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQ 537
Query: 520 DSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEE 579
+++DKSE+ F +AFVKLM DGTTL+DG HDL+VYK + KK+EDA YL+LP TK E+EE
Sbjct: 538 ETRDKSERAFGVAFVKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEE 597
Query: 580 KGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQL 639
K A+ + S +KDSFQI+TL+CSTKLTQNVDLLGLL WRSN+ ++ NL++L
Sbjct: 598 KELQASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKL 657
Query: 640 MKVDGGEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLE 699
M+VDGGE+VKFLQDTLDALFNIMME S+SET+D LVFDALVFII LI D KFQHFNPVLE
Sbjct: 658 MEVDGGEIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLE 717
Query: 700 TYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQL 759
TYI KHFSATLAY KL+KVL YV A+ E L+ A+KAL+ +F+FI++SR+L+ +
Sbjct: 718 TYIYKHFSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRF 777
Query: 760 Y-ENKGEADFVESLLQLFRSINDMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELS 818
Y ++K +F S+ QLF + N +M ++ V++KGAALKYLP+I+NDVKLVFDP ELS
Sbjct: 778 YGQSKDGDEFNNSIRQLFLAFNMLMDRPLEEAVKIKGAALKYLPSIINDVKLVFDPVELS 837
Query: 819 KMFTEFILNVPMGLLTIQKLYCLIEIVHSDLFTQHDCREILLPMMTDQLKYHLE---RQE 875
+F +FI ++P L QKL C+ +IV S LF Q +CRE+LLP++TDQL L+ +
Sbjct: 838 VLFCKFIQSIPDNQLVRQKLNCMTKIVESTLFRQSECREVLLPLLTDQLSGQLDDNSNKP 897
Query: 876 DLEACCQLLSHILEVLYRKDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACM 935
D EA QLLS+ILEVL RKDVG T H+Q+IME+LLR +NRTVI M R S IG+FVACM
Sbjct: 898 DHEASSQLLSNILEVLDRKDVGATAVHIQLIMERLLRRINRTVIGMNRQSPHIGSFVACM 957
Query: 936 TAILRQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKV 995
A+L+QM+D HY+H I TF K R D++DFLMETFIMFK+LIGKNVY DW++MNM QN+V
Sbjct: 958 IALLQQMDDSHYSHYISTF-KTRQDIIDFLMETFIMFKDLIGKNVYAKDWMVMNMTQNRV 1016
Query: 996 FLRAINQYADMLNKKFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKY 1055
FLRAINQ+A++L + F+DQA+FELQLWNNYFHLAVAFLT ESLQLE FS AKR KI+ KY
Sbjct: 1017 FLRAINQFAEVLTRFFMDQASFELQLWNNYFHLAVAFLTHESLQLETFSQAKRNKIVKKY 1076
Query: 1056 GDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEF 1115
GDMR++IGF IRDMWYNLG HKIKFIP MVGPILE+TL PE ELRKATIPIFFDMMQCEF
Sbjct: 1077 GDMRKEIGFRIRDMWYNLGPHKIKFIPSMVGPILEVTLTPEVELRKATIPIFFDMMQCEF 1136
Query: 1116 H--STRSFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKL 1173
+ +F MFENE+ITKLD EVEGGRGDEQYKVL +K+LLEHCRKHKYL+ +GE F L
Sbjct: 1137 NFSGNGNFHMFENELITKLDQEVEGGRGDEQYKVLLEKLLLEHCRKHKYLSSSGEVFALL 1196
Query: 1174 VVRLMERLLDYRTI-MHDENKENRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDN 1232
V L+E LLDYRTI M DE+KENRMSCTVNVLNFYKE +RE++YIRYLYKL DLH++C+N
Sbjct: 1197 VSSLLENLLDYRTIIMQDESKENRMSCTVNVLNFYKEKKREDIYIRYLYKLRDLHRDCEN 1256
Query: 1233 YTEAAYTLLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDKGKMWEE 1292
YTEAAYTLLLHA+LL+WS+ CV HL Q+D Y TQ +LKE+LYQEII YFDKGKMWE+
Sbjct: 1257 YTEAAYTLLLHAELLQWSDKPCVPHLLQKDSYYVYTQQELKEKLYQEIISYFDKGKMWEK 1316
Query: 1293 AIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPTFL 1352
AI L KELAE YE+++FDYE L LLKK+A FYENI+K +RP+P+YFAVGYYGQGFP+FL
Sbjct: 1317 AIKLSKELAETYESKVFDYEGLGNLLKKRASFYENIIKAMRPQPEYFAVGYYGQGFPSFL 1376
Query: 1353 RGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLD 1412
R K+FIYRGKEYERREDF RLLTQFPNAEKM +T+PPG+DIK+SP QY+QCFTVKP +
Sbjct: 1377 RNKIFIYRGKEYERREDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKPVMS 1436
Query: 1413 LPPKFH-RPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLP 1471
LPP + +PV EQI+++YR NEVQ+F YSRP RKGEK+PDNEFA MWIERT YTTAY P
Sbjct: 1437 LPPSYKDKPVPEQILNYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFP 1496
Query: 1472 GILRWFEVKSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVD 1531
GIL+WFEVK + EISPLENAIETM+LTN++I++ VQQH D SL ++PLSMLL+GIVD
Sbjct: 1497 GILKWFEVKQISTEEISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVD 1556
Query: 1532 PAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALR 1591
PAVMGGF+NYEKAFFT++YLQEHPE EK+E LK LIA Q+P L EGIRIHG+K+TE L+
Sbjct: 1557 PAVMGGFSNYEKAFFTEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLK 1616
Query: 1592 PFHERMEACFKQLKEKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASV- 1650
P HER+ +CF++LKEKVEK YGV +P +L +R+ SR S+V + M S+ R LS+ SV
Sbjct: 1617 PLHERLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSIVLPYIMSSTLRRLSITSVT 1676
Query: 1651 ------SSLSSDSTPSRPGSDGFALEPLLPKKMHS--RSQDKLDKDDLEKEK--KDKKKE 1700
SS SSD+ PSRPGSDG LEPLL ++ S R +D +++ + + K K+K+
Sbjct: 1677 SSVVSTSSNSSDNAPSRPGSDGSILEPLLERRASSGARVEDLSLREENSENRISKFKRKD 1736
Query: 1701 KRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRP-QRPKS-QVMNVIGSERRFSVS 1758
SK Q I EK +P + +SP R QRPKS Q+M+ R
Sbjct: 1737 WSLSKSQVIAEKAPEP--------------DLMSPTRKAQRPKSLQLMD----NRLSPFH 1778
Query: 1759 PSSP--SSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLME 1816
SSP S+ +PPP+TP+A + S S ++
Sbjct: 1779 GSSPPQSTPLSPPPLTPKATRTLSSPS-------------------------------LQ 1807
Query: 1817 NQDLLGSPTPPPPPPHQR----------HLPPPLP----SKTPPPPPPKTTR 1854
+ +P PPPPPP + L PPLP +K PPPPPPK +
Sbjct: 1808 TDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARK 1859
>gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
Length = 1830
Score = 2146 bits (5561), Expect = 0.0
Identities = 1081/1735 (62%), Positives = 1346/1735 (77%), Gaps = 22/1735 (1%)
Query: 10 EEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPASYIHLKE 69
+E++GVA YN+ GA +LSLQIGD V I ET WYRGY ++ K +GIFP S+IH+KE
Sbjct: 9 KERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFPKSFIHIKE 68
Query: 70 AIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWR 129
VE + E +IP ++PL QEVTTTL EW +IW+QLYV +E F V+ M+YDL+EWR
Sbjct: 69 VTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSMMYDLMEWR 128
Query: 130 SQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHE 189
SQ+LSGTLP+DELKELK+KVT+KIDYGN+IL+LDL+VRDEDGNILDP+ TS ISLF AHE
Sbjct: 129 SQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSVISLFHAHE 188
Query: 190 IASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDP 249
A+ ++ ER++EE S+ Q D ++ +++P+ +L+V ++N VC+IGEDAE+ MSLYDP
Sbjct: 189 EATDKITERIKEEMSKDQP-DYAMYSRISSSPTHSLYVFVRNFVCRIGEDAELFMSLYDP 247
Query: 250 VESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMEL 309
+ ISENYLVRW S G PK+I+ L+NL+ VFTDLG+KDL R+KI +CQIVRVG+M+L
Sbjct: 248 NKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRVGKMDL 307
Query: 310 RDNNTRKLTSGLRRPFGVAVMDVTDIINGKVD-DEDKQHFIPFQPVAGENDFLQTVINKV 368
+D +K T GLRRPFGVAVMD+TDII GK + DE+KQHFIPF PV ENDFL +++ KV
Sbjct: 308 KDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDFLHSLLGKV 367
Query: 369 IAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDI 428
IA+K + GQGLWVT+K+L GDI QIRK++PHLVDRTT VARK GFPEIIMPGDVRNDI
Sbjct: 368 IASKG-DSGGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPGDVRNDI 426
Query: 429 YVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQ 488
Y+TL+QGDFDK +KTT +NVEV + V EDGK L + I GAGD+ ++EY+SV+YYQVKQ
Sbjct: 427 YITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVVYYQVKQ 486
Query: 489 PRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGE 548
PRW ETVKVA+PIED+ R HLRF FRHRSS +SKDK EK FA+++VKLM+ DGTTL DG
Sbjct: 487 PRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGTTLHDGF 546
Query: 549 HDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLV 608
HDL+V K ++KK+EDA+ YL+LPS + +E KG + + S G S+D F ISTLV
Sbjct: 547 HDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLV 606
Query: 609 CSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSES 668
CSTKLTQNV LLGLLKWR LLQ+NL +L VDG EVVKFLQDTLDALFNIMME+S+S
Sbjct: 607 CSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIMMEHSQS 666
Query: 669 ETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEK 728
+ +D LVFDAL++IIGLIADRKFQHFN VLE YI++HFSATLAY KL VLK Y+D + +
Sbjct: 667 DEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTYLDTSSR 726
Query: 729 PGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMSD 788
E + + +KALE +FKFIVRSR LF+QLYE K + +F ES+ +LF SIN++M S
Sbjct: 727 GEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNLMKSQYK 786
Query: 789 QTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIVHSD 848
T+ ++ AALKY+P++++DV++VFD K LS++ EF +P L QK+ + EIV S+
Sbjct: 787 TTILLQVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMNEIVQSN 846
Query: 849 LFTQHDCREILLPMMTDQLKYHLERQEDLEA-------CCQLLSHILEVLYRKDVGPTQR 901
LF + +CR+ILLP++T +LK LE+++D++ C +LL+ ILEVL +D T
Sbjct: 847 LFKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQDAAFTYH 906
Query: 902 HVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTDV 961
H+Q IM +LLRTVNRTVI+MGRD LI +FVACMTAIL QM D HY+ I+TF + +++
Sbjct: 907 HIQEIMVQLLRTVNRTVITMGRDHILISHFVACMTAILNQMGDQHYSFYIETF-QTSSEL 965
Query: 962 VDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQL 1021
VDFLMETFIMFK+LIGKNVYP DW+ M+MVQN+VFLRAIN++A+ +N+KFL+ NFE QL
Sbjct: 966 VDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFLEHTNFEFQL 1025
Query: 1022 WNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFI 1081
WNNYFHLAVAF+TQ+SLQLE FS AK KILNKYGDMRR IGF IRDMWY LGQ+KI FI
Sbjct: 1026 WNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFI 1085
Query: 1082 PEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGRG 1141
P MVGPILEMTLIPE ELRKATIPIFFDMM CE+ + F+ FENEII KLDHEVEGGRG
Sbjct: 1086 PGMVGPILEMTLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRG 1145
Query: 1142 DEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCTV 1201
DEQY L + IL+E +H +AK+ E FV LV L+E+LLDYR +M DE+K+NRMSCTV
Sbjct: 1146 DEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKLLDYRGVMTDESKDNRMSCTV 1205
Query: 1202 NVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQR 1261
N+LNFYK+ REEMYIRYLYKL DLH +CDNYTEAAYTLLLH LLKWS++ C + + Q
Sbjct: 1206 NLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQT 1265
Query: 1262 DGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKKQ 1321
T QLKE LY+ II YFDKGKMWEEAI+L KELAEQYE E+FDYE LS+ L +Q
Sbjct: 1266 GQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQ 1325
Query: 1322 AQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPNA 1381
A+FYE+I+K++RPKPDYFAVGYYGQGFP+FLR KVFIYRGKEYERREDF+ +L+TQFPNA
Sbjct: 1326 AKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQFPNA 1385
Query: 1382 EKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKF-HRPVSEQIVSFYRVNEVQRFEYS 1440
EKM TTS PGDD+KN+PGQYIQCFTV+P LD P+F ++PV +QI++FY+ N VQRF YS
Sbjct: 1386 EKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYS 1445
Query: 1441 RPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLT 1500
RP+R+G +P+NEFA+MWIERT + TAYKLPGILRWFEV + ISPLENAIETM
Sbjct: 1446 RPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTA 1505
Query: 1501 NDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEK 1560
N+KI M+ Q+ D +LPINPLSMLLNGIVDPAVMGGFA YEKAFFT+ Y+++HPE +K
Sbjct: 1506 NEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDK 1565
Query: 1561 IEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSS 1620
+ LKDLIAWQIPFL GI+IH +V++ LRPFH+RME CFK LK KVEKEYGVR MP
Sbjct: 1566 LTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMP-D 1624
Query: 1621 LDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSD-STPSRPGSDGFALEPLLPKKMHS 1679
DDRR RPRSM+RS+ R +S+ S++S++SD STPS+P S+ F LE PK
Sbjct: 1625 FDDRRVGRPRSMLRSY------RQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRV 1678
Query: 1680 RSQDKLDKDDLEKEKKDKKKEKRNSKHQEIF--EKEFKPTDISLQQSEAVILSET 1732
++ + E K ++ +KR + +F EK +D+ + +S+T
Sbjct: 1679 EQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSRKHEFMSDT 1733
>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
Length = 2030
Score = 1201 bits (3106), Expect = 0.0
Identities = 686/1714 (40%), Positives = 1039/1714 (60%), Gaps = 76/1714 (4%)
Query: 4 WVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS 63
W PT+ EEKYGV ++ L L+IG+TV ILE EGWYRG + +K + KGIFPA+
Sbjct: 2 WTPTE-EEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGIFPAN 60
Query: 64 YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIY 123
YIHLK+AIV +GQ+ETV+P + ++ EVT TL+EW+++W+QLYV+ ++F +RH++
Sbjct: 61 YIHLKKAIVSNRGQYETVVPLEDSIVTEVTATLQEWASLWKQLYVKHKVDLFYKLRHVMN 120
Query: 124 DLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTIS 183
+LI+ R Q+LSG L QD+++E+K+ +T ++D+GN L LDLV R +D ++D + S
Sbjct: 121 ELIDLRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPR-KDFEVVDSDQISVSD 179
Query: 184 LFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCK-IGEDAEV 242
L++ H ++S+Q +Q+ SQ + F++LK+ IGED +V
Sbjct: 180 LYKMH-LSSRQ---SVQQSTSQVDTMRPRHGETCRMPVPHHFFLSLKSFTYNTIGEDTDV 235
Query: 243 LMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIV 302
SLYD E K ISE +LVR + +G P++ +++ + A+FTDL SKD+KR+ + V ++
Sbjct: 236 FFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRD-LYIVAHVI 294
Query: 303 RVGRMELRDNNTRKLTSGLRRPFGVAVMDVTDIINGKVD-DEDKQHFIPFQPVAGENDFL 361
R+GRM L D+ RRP+G AV+ + D++ + E+K + E+++
Sbjct: 295 RIGRMLLNDSKKGPPHLHYRRPYGCAVLSILDVLQSLTEVKEEKDFVLKVYTCNNESEWS 354
Query: 362 Q---TVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEI 418
Q +I K A GL ++L+LL GD+ QIR+E P + +R A+ RK GFP++
Sbjct: 355 QIHENIIRKSSAKYSAPSASHGLIISLQLLRGDMEQIRRENPMIFNRGLAITRKLGFPDV 414
Query: 419 IMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEY 478
IMPGD+RND+Y+TL +GDF++G K+ KN+EVT+ V DG+ L+ I G+G+ S Y
Sbjct: 415 IMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSY 474
Query: 479 KSVIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMR 538
S + Y PRW E +K+ IPI+ SHLRF FRH S++D +K K+F AF LMR
Sbjct: 475 HSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEK--KLFGFAFSTLMR 532
Query: 539 YDGTTLRDGEHDLIVYKA-EAKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTI 597
DGTTL D H+L VYK E + A YL LP K + ++ SL
Sbjct: 533 DDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKED-----YNGCPNIPSSLIFQRS 587
Query: 598 SKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDA 657
+K+SF IST + STKLTQNVDLL LLKW++ + L +L V G E+VKFLQD LD
Sbjct: 588 TKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDVLGRLRHVSGEEIVKFLQDILDT 647
Query: 658 LFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTK 717
LF I+ +N+E + LVF +LVFII L+ D K+ HF PV++TYI+KHF+ LAY +L +
Sbjct: 648 LFVILDDNTEK--YGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIR 705
Query: 718 VLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFR 777
LK Y+D + + + + +AM+ALE +FKFIV+SRIL+++ E F S+ +LF+
Sbjct: 706 CLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQ 765
Query: 778 SINDMM---SSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGL-- 832
SI ++ S S+ + + A L PTI +++ +F +E+++ + ++P +
Sbjct: 766 SIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHI 825
Query: 833 ---LTIQKLYCLIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILE 889
+ + KL + V S LF+ + R ILLP++ + HL +Q++L C +L I
Sbjct: 826 GQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFS 885
Query: 890 VLYRKDV-GPTQRHVQIIMEKLLRTVNRTVISMGRDS----------------ELIGNFV 932
++ + V++++E LL + +T++++ S E+ G +V
Sbjct: 886 IVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYV 945
Query: 933 ACMTAILRQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQ 992
+C+ ++LRQM D H+ HL+ F + + ++ +FL++ F +F+NL+ +V+P DW++M ++
Sbjct: 946 SCLLSLLRQMCDTHFQHLLDNF-QSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLT 1004
Query: 993 NKVFLRAINQYADMLNKKFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKIL 1052
+ + + + + L+K F + +F+ ++WN+YF LAV F+ Q SLQLE +SAKR KIL
Sbjct: 1005 SNIIVTTVQYLSSALHKNF-TETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKIL 1063
Query: 1053 NKYGDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQ 1112
+KYGDMR + +E+ MW NLG+HKI FIP M+GP L +TL+P+ E+R IPIF DMM
Sbjct: 1064 DKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMD 1123
Query: 1113 CEFHSTRSFQMFENEIITKLDHEVEGGRGDEQYKVLFDKI---------LLEHCRKHKYL 1163
E +F+ E E+I KLD V G+GDE Y+ LF + LLE + +
Sbjct: 1124 WEQRKNGNFKQVEAELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETW- 1182
Query: 1164 AKTGETFVKLVVRLMERLLDYRTIMHDENKEN-RMSCTVNVLNFYK-EIEREEMYIRYLY 1221
+TG +FV V RLMERLLDYR M E EN ++ CTVN++NFYK EI +EEMYIRY++
Sbjct: 1183 RETGISFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIH 1242
Query: 1222 KLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEII 1281
KLCD+H + +NYTEAA+TLLL+ +LL+W + L + Y + T+ Q KE L ++II
Sbjct: 1243 KLCDMHLQAENYTEAAFTLLLYCELLQWED----RPLREFLHYPSQTEWQRKEGLCRKII 1298
Query: 1282 HYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAV 1341
HYF+KGK WE I L +ELA QYE+ ++DY+ LS + K +A +Y+NI++ R +P++F V
Sbjct: 1299 HYFNKGKSWEFGIPLCRELACQYES-LYDYQSLSWIRKMEASYYDNIMEQQRLEPEFFRV 1357
Query: 1342 GYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQY 1401
G+YG+ FP FLR K ++ RG +YER E F+ R+L++FP A M+ + P D I QY
Sbjct: 1358 GFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQY 1417
Query: 1402 IQCFTVKPKLDLPPKFHRP-VSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIE 1460
+Q + V P D V +++ SFYRVN V++F Y RP KG K+ +NEF ++WIE
Sbjct: 1418 LQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIE 1477
Query: 1461 RTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKINSMVQQHL-DDPSLPI 1519
RT T + LPGI RWFEV+ +VE+SPLENAI+ ++ N ++ S++ Q+ I
Sbjct: 1478 RTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRSLISQYQHKQVHGNI 1537
Query: 1520 NPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGI 1579
N LSM LNG++D AV GG A Y++AFF Y+ +HP EKI +LK+L+ Q+ L G+
Sbjct: 1538 NLLSMCLNGVIDAAVNGGIARYQEAFFDKDYINKHPGDAEKITQLKELMQEQVHVLGVGL 1597
Query: 1580 RIHGDKVTEALRPFHERMEACFKQLKEKVEKEY-GV-RIMP--SSLDDRRG----SRPRS 1631
+H V +RP H+++ F+ ++ + E+ G+ ++ P S RG S
Sbjct: 1598 AVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPM 1657
Query: 1632 MVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSD 1665
S M P+++ SS S S S+
Sbjct: 1658 SPESIKMTHRHSPMNLMGTGRHSSSSLSSHASSE 1691
>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
Length = 1966
Score = 1189 bits (3075), Expect = 0.0
Identities = 699/1878 (37%), Positives = 1071/1878 (57%), Gaps = 99/1878 (5%)
Query: 4 WVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS 63
W+PT+ E KYGV ++ LSL+IGDTV ILE +GWYRG+ L+ + KGIFP+S
Sbjct: 2 WIPTEHE-KYGVVIASFRGTVPYGLSLEIGDTVQILEKCDGWYRGFALKNPNIKGIFPSS 60
Query: 64 YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIY 123
Y+HLK A V+ KGQ E VIP + +I E+T+TLR+W T+W+QLYV++ ++F + H++
Sbjct: 61 YVHLKNACVKNKGQFEMVIPTEDSVITEMTSTLRDWGTMWKQLYVRNEGDLFHRLWHIMN 120
Query: 124 DLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTIS 183
++++ R Q+L G L D +K++K+ +TA++D+GN L LDLV R E ++DPE S
Sbjct: 121 EILDLRRQVLVGHLTHDRMKDVKRHITARLDWGNEQLGLDLVPRKEYA-MVDPEDISITE 179
Query: 184 LFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVC-KIGEDAEV 242
L+ RL E + +K++ + S LFV +K+++C +GE+ EV
Sbjct: 180 LY------------RLMEHRHRKKDTPVQ-------ASSHHLFVQMKSLMCSNLGEELEV 220
Query: 243 LMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIV 302
+ SL+D E++ ISE + +R + +GLPK D+ ++F DLGS +L+++ I I+
Sbjct: 221 IFSLFDSKENRPISERFFLRLNRNGLPKAPDKPERHCSLFVDLGSSELRKD-IYITVHII 279
Query: 303 RVGRMELRDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQ 362
R+GRM + + RRPFG AV+ + D++ G+ D+ + +
Sbjct: 280 RIGRMGAGEKK-NACSVQYRRPFGCAVLSIADLLTGETKDDLILKVYMCNTESEWYQIHE 338
Query: 363 TVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPG 422
+I K+ A + GL V+L+LL GDI QIR+E+ + ++ RK GF IIMPG
Sbjct: 339 NIIKKLNARYNLTGSNAGLAVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPG 398
Query: 423 DVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVI 482
++RND+Y+T+ +G+F+KG K+ A+NVEVT+ + D G+ L+ I G+G+ SEY S +
Sbjct: 399 EMRNDLYITIERGEFEKGGKSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFV 458
Query: 483 YYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGT 542
Y PRW E +K+ IP++ +H+RF FRH S+++ +K K+F +FV LM+ DG
Sbjct: 459 LYHNNSPRWSELLKLPIPVDKFRGAHIRFEFRHCSTKEKGEK--KLFGFSFVPLMQEDGR 516
Query: 543 TLRDGEHDLIVYKAEAK-KLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDS 601
TL DG H+LIV+K E L+D YL LP +K G + Q++ + +K+S
Sbjct: 517 TLPDGTHELIVHKCEENTNLQDTTRYLKLPFSKGIF-------LGNNNQAMKA---TKES 566
Query: 602 FQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFNI 661
F I++ +CSTKLTQN D+L LLKWR++ + L +L ++DG E+VKFLQDTLD LF I
Sbjct: 567 FCITSFLCSTKLTQNGDMLDLLKWRTHPDKITGCLSKLKEIDGSEIVKFLQDTLDTLFGI 626
Query: 662 MMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKN 721
+ ENS+ + + VFD+LV II L+ D KF HF PV++TYI+ HF+ LAY L KVLK
Sbjct: 627 LDENSQK--YGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKW 684
Query: 722 YVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADF---VESLLQLFRS 778
YVD + E + + +KA E IFK+IV+SR LF+ + E +F ++ LL R
Sbjct: 685 YVDRITEAERQEHIQEVLKAQEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELLMSVRF 744
Query: 779 INDMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGL-----L 833
S S + + L P + +++ +FD +E++ + + + ++P L L
Sbjct: 745 FLSQESKGSGALSQSQAVFLSSFPAVYSELLKLFDVREVANLVQDTLGSLPTILHVDDSL 804
Query: 834 TIQKLYCLIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYR 893
KL C+ + V S L+T D R ILLP++ L HL+ Q+DL C ++LS++ ++ +
Sbjct: 805 QAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHIHLQEQKDLIMCARILSNVFCLIKK 864
Query: 894 KDVGPT-QRHVQIIMEKLLRTVNRTVISMG------------RDSELIGNFVACMTAILR 940
+ + +I+ LL + RT++ + + ++ G FVAC+ ++LR
Sbjct: 865 NSSEKSVLEEIDVIVASLLDILLRTILEITSRPQPSSSAMRFQFQDVTGEFVACLLSLLR 924
Query: 941 QMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAI 1000
QM D HY L+ +F + ++ DFL++ F +F+ LI ++P DW +M +V N V + +
Sbjct: 925 QMTDRHYQQLLDSF-NTKEELRDFLLQIFTVFRILIRPEMFPKDWTVMRLVANNVIITTV 983
Query: 1001 NQYADMLNKKFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRR 1060
+D L K FL++ NF+ ++W++YF+LAV F+ Q LQLE F+ +K+ K+L KYGDMR
Sbjct: 984 LYLSDALRKNFLNE-NFDYKIWDSYFYLAVIFINQLCLQLEMFTPSKKKKVLEKYGDMRV 1042
Query: 1061 QIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTRS 1120
+G EI MW NLG+HK+ FIP ++GP LE+TLIP+ +LR IPIF DMM E + +
Sbjct: 1043 TMGCEIFSMWQNLGEHKLHFIPALIGPFLEVTLIPQPDLRNVMIPIFHDMMDWEQRRSGN 1102
Query: 1121 FQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMER 1180
F+ E ++I KLD + G+GDE Y+ LF+ ILL+ + + ++G + + V RLMER
Sbjct: 1103 FKQVEAKLIDKLDSLMSEGKGDETYRELFNSILLKKIERETW-RESGVSLIATVTRLMER 1161
Query: 1181 LLDYRTIMH-DENKENRMSCTVNVLNFYK-EIEREEMYIRYLYKLCDLHKECDNYTEAAY 1238
LLDYR M E ++ CTV++LNFYK E+ +EEMYIRY++KL DLH + N+TEAAY
Sbjct: 1162 LLDYRDCMKMGEVDGKKIGCTVSLLNFYKTELNKEEMYIRYIHKLYDLHLKAQNFTEAAY 1221
Query: 1239 TLLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGK 1298
TLLL+ +LL+WS+ LT Y T+ Q KE L+ II FD+GK WE I L +
Sbjct: 1222 TLLLYDELLEWSDRPLREFLT----YPMQTEWQRKEHLHLTIIQNFDRGKCWENGIILCR 1277
Query: 1299 ELAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFI 1358
++AEQYE+ +DY LS++ +A Y+ I+ R +P++F VG+YG+ FP FLR K F+
Sbjct: 1278 KIAEQYES-YYDYRNLSKMRMMEASLYDKIMDQQRLEPEFFRVGFYGKKFPFFLRNKEFV 1336
Query: 1359 YRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFH 1418
RG +YER E F+ R+L +FP+A M+ + P + I + QY+Q + V P +
Sbjct: 1337 CRGHDYERLEAFQQRMLNEFPHAIAMQHANQPDETIFQAEAQYLQIYAVTPIPESQEVLQ 1396
Query: 1419 RP-VSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWF 1477
R V + I SFY+VN + +F Y RP KG K+ +NEF ++W+ERT LPGI RWF
Sbjct: 1397 REGVPDNIKSFYKVNHIWKFRYDRPFHKGTKDKENEFKSLWVERTSLYLVQSLPGISRWF 1456
Query: 1478 EVKSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGG 1537
EV+ +VE+SPLENAIE ++ N ++ +++ Q INPL+M LNG++D AV GG
Sbjct: 1457 EVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQTRQMQNINPLTMCLNGVIDAAVNGG 1516
Query: 1538 FANYEKAFFTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERM 1597
+ Y++AFF Y+ HPE EKI +L++L+ Q L G+ +H V + +RP H+++
Sbjct: 1517 VSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQAQILEFGLAVHEKFVPQDMRPLHKKL 1576
Query: 1598 EACFKQLKEKVE-KEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSD 1656
F +K + +E+ + S + GS P R + ASVS +
Sbjct: 1577 VDQFFVMKSSLGIQEFSACMQASPVHFPNGS-----------PRVCRNSAPASVSPDGTR 1625
Query: 1657 STPSRPGSDGFALEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKP 1716
P R A+ + S++ ++ + E D E+F + P
Sbjct: 1626 VIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITGQSESSD-----------EVFNMQPSP 1674
Query: 1717 TDISLQQSEAVILSETISPLRPQRPKSQVMNVIGSERRFS-VSP-SSPSSQQTPPPVTPR 1774
+ SL + + + T S R + + R S +SP P S P PV P
Sbjct: 1675 STSSLSSTHSASPNVTSSAPSSARASPLLSDKHKHSRENSCLSPRERPCSAIYPTPVEPS 1734
Query: 1775 AKLSFSM--QSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPH 1832
++ F+ +L + + P P S+ D G +N G PP PP
Sbjct: 1735 QRMLFNHIGDGALPRSDPNLSAPEKAVNPTPSSWSL-DSGKEAKNMSDSGKLISPPVPPR 1793
Query: 1833 QRHLPPPLPSKTPPPPPP 1850
P T P P
Sbjct: 1794 PTQTASPARHTTSVSPSP 1811
>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
Length = 2186
Score = 77.4 bits (189), Expect = 1e-13
Identities = 85/410 (20%), Positives = 168/410 (40%), Gaps = 31/410 (7%)
Query: 1258 LTQRDGYQATTQGQ--LKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLS 1315
+ + G Q T + L EQLY + + K + +E + K + +E + D+++LS
Sbjct: 1793 MKEDSGMQDTPYNENILVEQLYM-CVEFLWKSERYELIADVNKPIIAVFEKQR-DFKKLS 1850
Query: 1316 ELLKKQAQFYENIVKVIRPKPD----YFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFE 1371
+L + Y + +V+ + Y+ V +YGQGF GK +IY+ + +
Sbjct: 1851 DLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEIS 1910
Query: 1372 ARLLTQFPNAEKMKTTSPPGDDIKNSPGQ------YIQCFTVKPKLDLPPKFHRPVSEQI 1425
RLL + + D K +P YIQ V P + + + ++
Sbjct: 1911 QRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFE-----EKEIEDRK 1965
Query: 1426 VSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMV 1485
F + + RF + P K A RTI TT++ P + + +V S
Sbjct: 1966 TDFEMHHNINRFVFETPFTLSGKKHGG-VAEQCKRRTILTTSHLFPYVKKRIQVISQSST 2024
Query: 1486 EISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAF 1545
E++P+E AI+ M ++N + + + L + L G V V G Y +AF
Sbjct: 2025 ELNPIEVAIDEMSKKVSELNQLCTME----EVDMIRLQLKLQGSVSVKVNAGPMAYARAF 2080
Query: 1546 FTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLK 1605
+ +++P+ +++ LK++ + + ++ + E + E + + +K +
Sbjct: 2081 LEETNAKKYPD--NQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDML 2138
Query: 1606 EKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSS 1655
++ +M + R R + ++ T S ++ +VS SS
Sbjct: 2139 SELS-----TVMNEQITGRDDLSKRGVDQTCTRVISKATPALPTVSISSS 2183
Score = 48.1 bits (113), Expect = 8e-05
Identities = 76/351 (21%), Positives = 146/351 (41%), Gaps = 45/351 (12%)
Query: 425 RNDIYVTLVQGDFDKGSK-TTAKNVEVTVSVYDED---GKRLEHVIFPGAGDEAISEYKS 480
+N IY+ +D A+N+ V + + D K L+ + G S +
Sbjct: 672 KNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAAYT 731
Query: 481 VIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRH-------RSSQDSKDKSEKIFALAF 533
+ + + P + + VK+ +P + + H+ F+F H +++ K+ E A+
Sbjct: 732 AVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALETSVGYAW 791
Query: 534 VKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSATGKSMQS-L 592
+ LM++D + E+++ + AT SLP ++ SA+GK S +
Sbjct: 792 LPLMKHD--QIASQEYNIPI-----------AT--SLPPNYLSFQD---SASGKHGGSDI 833
Query: 593 GSCTISKDSFQISTLVCSTKLTQNVDLLGLLK---------WRSNTSLLQQNLRQLMKVD 643
K F++ST V ST TQ+ + + +S TS ++ + L+ V+
Sbjct: 834 KWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVE 893
Query: 644 G-GEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYI 702
++ FL L+ LF ++++N E E T V L I+ + + H +++YI
Sbjct: 894 KIHAIMSFLPIILNQLFKVLVQNEEDE-ITTTVTRVLTDIVAKCHEEQLDH---SVQSYI 949
Query: 703 KKHFSATLAYTK-LTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRS 752
K F + + + L V G K + + +K F I++S
Sbjct: 950 KFVFKTRACKERTVHEELAKNVTGLLKSNDSTTVKHVLKHSWFFFAIILKS 1000
>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
Length = 2073
Score = 69.3 bits (168), Expect = 3e-11
Identities = 69/344 (20%), Positives = 146/344 (42%), Gaps = 23/344 (6%)
Query: 1275 QLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRP 1334
+L ++ + K + +E + K + YE ++E+L+++ + Y I++V+
Sbjct: 1697 ELLEQCVDGLWKAERYEIISEISKLIVPIYEKRR-EFEKLTQVYRTLHGAYTKILEVMHT 1755
Query: 1335 KP----DYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQF------PNAEKM 1384
K +F V +YGQ F GK +IY+ + + RL+ + N + +
Sbjct: 1756 KKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKII 1815
Query: 1385 KTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIR 1444
+ + + +IQ VKP D + ++E+ F R + + RF + P
Sbjct: 1816 QDSDKVNAKELDPKYAHIQVTYVKPYFD-----DKELTERKTEFERNHNISRFVFEAPYT 1870
Query: 1445 KGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKI 1504
K RTI TT+ P + + + + + P++ A + ++ DK
Sbjct: 1871 LSGKK-QGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIK---DK- 1925
Query: 1505 NSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKL 1564
+ +Q+ + + L + L G V V G Y +AF D ++P +K+ +L
Sbjct: 1926 TAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPP--KKVSEL 1983
Query: 1565 KDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKV 1608
KD+ I + + ++ + E +HE +++ F+ + +++
Sbjct: 1984 KDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKEL 2027
Score = 42.0 bits (97), Expect = 0.006
Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 13/126 (10%)
Query: 425 RNDIYVTLVQGDFDKGSKTTAK--NVEVTVSVYDED---GKRLEHVIFPGAGDEAISEYK 479
+N +YV +Q +D KT AK N+ V V D D L+ + AG +
Sbjct: 640 KNHLYVYPLQLKYDS-QKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAY 698
Query: 480 SVIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRH-------RSSQDSKDKSEKIFALA 532
+V+ + + P +++ +K+ +PI + HL FTF H + + +D E A
Sbjct: 699 AVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFA 758
Query: 533 FVKLMR 538
+V L++
Sbjct: 759 WVPLLK 764
>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
Length = 2068
Score = 65.1 bits (157), Expect = 6e-10
Identities = 80/387 (20%), Positives = 153/387 (39%), Gaps = 58/387 (14%)
Query: 1249 WSEDVCVAHLTQ-RDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENE 1307
++EDV + L Q DG + +L +Y+ II ++K +
Sbjct: 1708 FNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRR------------------- 1748
Query: 1308 MFDYEQLSELLKKQAQFYENIVKVI----RPKPDYFAVGYYGQ--------------GFP 1349
D+E+L+ L + Y + +V+ R YF V ++GQ GF
Sbjct: 1749 --DFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFF 1806
Query: 1350 TFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ------YIQ 1403
GK +IY+ + + RLL + + + D K +P YIQ
Sbjct: 1807 EDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQ 1866
Query: 1404 CFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTI 1463
V P D + + E+ F R + ++RF + P + K RTI
Sbjct: 1867 VTHVIPFFD-----EKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGG-VEEQCKRRTI 1920
Query: 1464 YTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLS 1523
T + P + + V +++P+E AI+ M K + ++Q + + L
Sbjct: 1921 LTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMS----KKVAELRQLCSSAEVDMIKLQ 1976
Query: 1524 MLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHG 1583
+ L G V V G Y +AF D + +P+ K++ LK++ + + + ++
Sbjct: 1977 LKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPD--NKVKLLKEVFRQFVEACGQALAVNE 2034
Query: 1584 DKVTEALRPFHERMEACFKQLKEKVEK 1610
+ E + E M+A ++++ +++ +
Sbjct: 2035 RLIKEDQLEYQEEMKANYREMAKELSE 2061
Score = 45.8 bits (107), Expect = 4e-04
Identities = 75/342 (21%), Positives = 146/342 (42%), Gaps = 43/342 (12%)
Query: 428 IYVTLVQGDFDKGSKTTAKNVEVTVSVYD---EDGKRLEHVIF-PGAGDEAISEYKSVIY 483
+Y ++ D K S A+N+ + + D ED + L+ + PG S + +V++
Sbjct: 644 VYPKYLKYDSQK-SFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702
Query: 484 YQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTT 543
+ + P +++ +K+ +P + + HL TF H S +S S K + ++
Sbjct: 703 HH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPL 761
Query: 544 LRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSA-TGKSMQSLGSCTISKDSF 602
L+DG V +E + +LPS +E G G ++ + K
Sbjct: 762 LKDGR----VVTSE----QHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDG---GKPLL 810
Query: 603 QISTLVCSTKLTQNVDLLGLLKWRSNT--------SLLQQNLRQLMKVDGGEVVKFLQDT 654
+IST + ST TQ+ L ++ T + L + L+ L ++G ++ FL
Sbjct: 811 KISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTI 870
Query: 655 LDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTK 714
L+ LF ++ ++ E + + II ++A + L +Y+K + A
Sbjct: 871 LNQLFRVLTRATQEE----VAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKA------ 920
Query: 715 LTKVLKNYVDGAEKPGVNEQLYKAMKA-LESIFKFIVRSRIL 755
+ YV +E V+E+L K+M L+ F+ +++L
Sbjct: 921 -----EPYV-ASEYKTVHEELTKSMTTILKPSADFLTSNKLL 956
>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
Length = 2069
Score = 65.1 bits (157), Expect = 6e-10
Identities = 80/387 (20%), Positives = 153/387 (39%), Gaps = 58/387 (14%)
Query: 1249 WSEDVCVAHLTQ-RDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENE 1307
++EDV + L Q DG + +L +Y+ II ++K +
Sbjct: 1709 FNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRR------------------- 1749
Query: 1308 MFDYEQLSELLKKQAQFYENIVKVI----RPKPDYFAVGYYGQ--------------GFP 1349
D+E+L+ L + Y + +V+ R YF V ++GQ GF
Sbjct: 1750 --DFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFF 1807
Query: 1350 TFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ------YIQ 1403
GK +IY+ + + RLL + + + D K +P YIQ
Sbjct: 1808 EDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQ 1867
Query: 1404 CFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTI 1463
V P D + + E+ F R + ++RF + P + K RTI
Sbjct: 1868 VTHVIPFFD-----EKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGG-VEEQCKRRTI 1921
Query: 1464 YTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLS 1523
T + P + + V +++P+E AI+ M K + ++Q + + L
Sbjct: 1922 LTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMS----KKVAELRQLCSSAEVDMIKLQ 1977
Query: 1524 MLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHG 1583
+ L G V V G Y +AF D + +P+ K++ LK++ + + + ++
Sbjct: 1978 LKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPD--NKVKLLKEVFRQFVEACGQALAVNE 2035
Query: 1584 DKVTEALRPFHERMEACFKQLKEKVEK 1610
+ E + E M+A ++++ +++ +
Sbjct: 2036 RLIKEDQLEYQEEMKANYREMAKELSE 2062
Score = 45.8 bits (107), Expect = 4e-04
Identities = 75/342 (21%), Positives = 146/342 (42%), Gaps = 43/342 (12%)
Query: 428 IYVTLVQGDFDKGSKTTAKNVEVTVSVYD---EDGKRLEHVIF-PGAGDEAISEYKSVIY 483
+Y ++ D K S A+N+ + + D ED + L+ + PG S + +V++
Sbjct: 645 VYPKYLKYDSQK-SFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703
Query: 484 YQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTT 543
+ + P +++ +K+ +P + + HL TF H S +S S K + ++
Sbjct: 704 HH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPL 762
Query: 544 LRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSA-TGKSMQSLGSCTISKDSF 602
L+DG V +E + +LPS +E G G ++ + K
Sbjct: 763 LKDGR----VVTSE----QHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDG---GKPLL 811
Query: 603 QISTLVCSTKLTQNVDLLGLLKWRSNT--------SLLQQNLRQLMKVDGGEVVKFLQDT 654
+IST + ST TQ+ L ++ T + L + L+ L ++G ++ FL
Sbjct: 812 KISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTI 871
Query: 655 LDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTK 714
L+ LF ++ ++ E + + II ++A + L +Y+K + A
Sbjct: 872 LNQLFRVLTRATQEE----VAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKA------ 921
Query: 715 LTKVLKNYVDGAEKPGVNEQLYKAMKA-LESIFKFIVRSRIL 755
+ YV +E V+E+L K+M L+ F+ +++L
Sbjct: 922 -----EPYV-ASEYKTVHEELTKSMTTILKPSADFLTSNKLL 957
>gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]
Length = 2109
Score = 58.5 bits (140), Expect = 6e-08
Identities = 102/464 (21%), Positives = 181/464 (39%), Gaps = 62/464 (13%)
Query: 1189 HDENKENRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLL----LHA 1244
H E+ E + + Y+ ++ + +L + H E N+ EAA L+ L A
Sbjct: 1631 HQEDPEMLIDLMYRIAKGYQT--SPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVA 1688
Query: 1245 KLLKWSED---VCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDK-----GKMWEEAIAL 1296
+ L ED + V +T +Q + L+E + + D+ GK + E+ +
Sbjct: 1689 EYLSMLEDRKYLPVGCVT----FQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLV 1744
Query: 1297 GK--------ELAEQYE--NEMF-----------DYEQLSELLKKQAQFYENIVKVI--- 1332
G +A YE NE++ D ++LS + K + + IV
Sbjct: 1745 GLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQSTGW 1804
Query: 1333 -RPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQF-----PNAEKMKT 1386
R YF VG+YG F L + F+Y+ + + RL + + ++
Sbjct: 1805 ERMFGTYFRVGFYGTKFGD-LDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIK 1863
Query: 1387 TSPPGDDIKNSPGQ-YIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIRK 1445
S P D K P + YIQ V+P D + ++I F + ++RF Y P
Sbjct: 1864 DSNPVDKCKLDPNKAYIQITYVEPYFDT-----YEMKDRITYFDKNYNLRRFMYCTPFTL 1918
Query: 1446 GEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKIN 1505
+ E + +TI TT++ P I V + ++P+E AIE MQ ++
Sbjct: 1919 -DGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELA 1977
Query: 1506 SMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLK 1565
Q DP + L M+L G V V G + F ++ + P+ KL+
Sbjct: 1978 FATHQDPADPKM----LQMVLQGSVGTTVNQGPLEVAQVFLSE--IPSDPKLFRHHNKLR 2031
Query: 1566 DLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVE 1609
+ +R + + + + +E + +LKE ++
Sbjct: 2032 LCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQ 2075
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 4/83 (4%)
Query: 444 TAKNVEVTVS-VYDEDGKRLEHVIFPGAGDEAISE--YKSVIYYQVKQPRWFETVKVAIP 500
+A+N+ V V +Y ED VIF + S+ Y +V+Y+ + P + E +KV +P
Sbjct: 579 SARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHN-RSPDFHEEIKVKLP 637
Query: 501 IEDVNRSHLRFTFRHRSSQDSKD 523
+ HL FTF H S Q ++
Sbjct: 638 ATLTDHHHLLFTFYHVSCQQKQN 660
>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
Length = 2099
Score = 58.2 bits (139), Expect = 8e-08
Identities = 101/475 (21%), Positives = 188/475 (39%), Gaps = 60/475 (12%)
Query: 1179 ERLLDYRTIMHD--------ENKENRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKEC 1230
E L + +I++D E+ E M + Y+ ++ + +L + + H +
Sbjct: 1598 ELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQA--SPDLRLTWLQNMAEKHTKK 1655
Query: 1231 DNYTEAAYTLLLHAKLLKWSEDVCVAHLTQRDG---YQATTQGQLKEQLYQEIIHYFDK- 1286
YTEAA L+ A L+ + H G +Q + L+E + E D+
Sbjct: 1656 KCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDED 1715
Query: 1287 ----GKMWEEA--IALGKELAEQYE--------NEMF-----------DYEQLSELLKKQ 1321
G+ + E+ + L ++ AE + NE++ ++ +L+ K
Sbjct: 1716 GVCAGQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKL 1775
Query: 1322 AQFYENIVKVIRPKP--DYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLT--- 1376
+ +++IV + YF VG++G F L + F+Y+ + + RL
Sbjct: 1776 QRAFDSIVNKDHKRMFGTYFRVGFFGSKFGD-LDEQEFVYKEPAITKLPEISHRLEAFYG 1834
Query: 1377 QFPNAEKMKTT--SPPGDDIKNSPGQ-YIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNE 1433
Q AE ++ S P D K P + YIQ V+P D + +++ F +
Sbjct: 1835 QCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFD-----EYEMKDRVTYFEKNFN 1889
Query: 1434 VQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENA 1493
++RF Y+ P E P E + T+ TT + P I V ++P+E A
Sbjct: 1890 LRRFMYTTPFTL-EGRPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVA 1948
Query: 1494 IETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQE 1553
IE M+ ++ + Q D + L M+L G V V G + F + +
Sbjct: 1949 IEDMKKKTLQLAVAINQEPPDAKM----LQMVLQGSVGATVNQGPLEVAQVFLAE--IPA 2002
Query: 1554 HPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKV 1608
P+ + KL+ I E + + +T R + + ++ + +LKE +
Sbjct: 2003 DPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENL 2057
Score = 49.3 bits (116), Expect = 4e-05
Identities = 70/310 (22%), Positives = 133/310 (42%), Gaps = 21/310 (6%)
Query: 397 KEFPHLVDRTTAVARKTGFP--EIIMPGDV-RNDIYVTLVQGDFDKGSKTTAKNVEVTVS 453
K FP +RT FP E+ +P V RN +YV + +F +A+N+ + +
Sbjct: 531 KPFPE--NRTRPHKEILEFPTREVYVPHTVYRNLLYVYPQRLNF-VNKLASARNITIKIQ 587
Query: 454 -VYDEDGKRLEHVIF-PGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIEDVNRSHLRF 511
+ ED VIF +G E + E + + Y K P ++E VK+ +P + HL F
Sbjct: 588 FMCGEDASNAMPVIFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLF 647
Query: 512 TFRHRSSQDSKDKS-EKIFALAFVKLMRYDGTTLRDGEHDLIV--YKAEAKKLEDAATYL 568
TF H S Q + S E + +++ ++ + L+ G + L V K +A +
Sbjct: 648 TFYHISCQQKQGASVETLLGYSWLPILLNE--RLQTGSYCLPVALEKLPPNYSMHSAEKV 705
Query: 569 SLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSN 628
L + + E +Q++ S + + +C + +Q + +L + +
Sbjct: 706 PLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKIS 765
Query: 629 TSLLQQNLR-QLMKVDGGE---VVKFLQDTLDALFNI----MMENSESETFDTLVFDALV 680
L+ L+ ++ ++ +V FL LD LF + M+ ++ F F+++V
Sbjct: 766 EMALEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVV 825
Query: 681 FIIGLIADRK 690
I + + K
Sbjct: 826 AIANSLHNSK 835
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 56.2 bits (134), Expect = 3e-07
Identities = 49/195 (25%), Positives = 82/195 (42%), Gaps = 50/195 (25%)
Query: 1673 LPKKMHSRSQDKLDKDDLEKEKKDK----KKEKRNSKHQEIFEKEFKPTDISLQQSEAVI 1728
L ++ Q++LD++ E++++++ ++E++ + QE E+E L+
Sbjct: 210 LERQERLERQERLDRERQERQERERLERLERERQERERQEQLERE------QLEWERERR 263
Query: 1729 LSETISPLRPQRPKSQVMNVIGSER---RFSVSPSSPSSQQ----------TPPPVTPRA 1775
+S +P + P + V+ + + + P+ SQQ PPP+ P
Sbjct: 264 ISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGP 323
Query: 1776 KLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRH 1835
Q+S+ L G PPP PL + G P PPPPPP
Sbjct: 324 A-----QASVALPPPPGP-----PPPPPLPST--------------GPPPPPPPPPLPNQ 359
Query: 1836 LPPPLPSKTPPPPPP 1850
+PPP P PPP PP
Sbjct: 360 VPPPPP---PPPAPP 371
Score = 52.8 bits (125), Expect = 3e-06
Identities = 49/204 (24%), Positives = 85/204 (41%), Gaps = 49/204 (24%)
Query: 1682 QDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDIS--------LQQSEAVILSETI 1733
+++++++ LE+E+ ++++ +R QE E+E + + L++ E + E +
Sbjct: 163 RERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERL 222
Query: 1734 SPLRPQRPKSQVMNVIGSER-------------------RFSVSPSSPSSQQTP------ 1768
R +R + + + + ER R S ++P+S +TP
Sbjct: 223 DRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLG 282
Query: 1769 --PPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTP 1826
P + + + G+ +A PPP PL A Q + P P
Sbjct: 283 DSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPP-PLPPGPA--------QASVALPPP 333
Query: 1827 PPPPPHQRHLPPPLPSKTPPPPPP 1850
P PPP PPPLPS PPPPPP
Sbjct: 334 PGPPP-----PPPLPSTGPPPPPP 352
Score = 44.3 bits (103), Expect = 0.001
Identities = 46/185 (24%), Positives = 79/185 (42%), Gaps = 40/185 (21%)
Query: 1682 QDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQRP 1741
Q++L+++ E+E++++ + + + QE E++ + D Q+ + E + R +R
Sbjct: 188 QEQLERERQERERQERLERQERLERQERLERQER-LDRERQERQERERLERLERERQERE 246
Query: 1742 KSQVMN----VIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVAD 1797
+ + + ERR S S ++P+S +TP LN + G A
Sbjct: 247 RQEQLEREQLEWERERRIS-SAAAPASVETP------------------LNSVLGDSSAS 287
Query: 1798 VPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPP---------PLPSKTPPPP 1848
P L+ + + +LG PPPPPP LPP P P PPPP
Sbjct: 288 EPG---LQAASQPAETPSQQGIVLGPLAPPPPPP----LPPGPAQASVALPPPPGPPPPP 340
Query: 1849 PPKTT 1853
P +T
Sbjct: 341 PLPST 345
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 56.2 bits (134), Expect = 3e-07
Identities = 49/195 (25%), Positives = 82/195 (42%), Gaps = 50/195 (25%)
Query: 1673 LPKKMHSRSQDKLDKDDLEKEKKDK----KKEKRNSKHQEIFEKEFKPTDISLQQSEAVI 1728
L ++ Q++LD++ E++++++ ++E++ + QE E+E L+
Sbjct: 210 LERQERLERQERLDRERQERQERERLERLERERQERERQEQLERE------QLEWERERR 263
Query: 1729 LSETISPLRPQRPKSQVMNVIGSER---RFSVSPSSPSSQQ----------TPPPVTPRA 1775
+S +P + P + V+ + + + P+ SQQ PPP+ P
Sbjct: 264 ISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGP 323
Query: 1776 KLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRH 1835
Q+S+ L G PPP PL + G P PPPPPP
Sbjct: 324 A-----QASVALPPPPGP-----PPPPPLPST--------------GPPPPPPPPPLPNQ 359
Query: 1836 LPPPLPSKTPPPPPP 1850
+PPP P PPP PP
Sbjct: 360 VPPPPP---PPPAPP 371
Score = 52.8 bits (125), Expect = 3e-06
Identities = 49/204 (24%), Positives = 85/204 (41%), Gaps = 49/204 (24%)
Query: 1682 QDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDIS--------LQQSEAVILSETI 1733
+++++++ LE+E+ ++++ +R QE E+E + + L++ E + E +
Sbjct: 163 RERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERL 222
Query: 1734 SPLRPQRPKSQVMNVIGSER-------------------RFSVSPSSPSSQQTP------ 1768
R +R + + + + ER R S ++P+S +TP
Sbjct: 223 DRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLG 282
Query: 1769 --PPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTP 1826
P + + + G+ +A PPP PL A Q + P P
Sbjct: 283 DSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPP-PLPPGPA--------QASVALPPP 333
Query: 1827 PPPPPHQRHLPPPLPSKTPPPPPP 1850
P PPP PPPLPS PPPPPP
Sbjct: 334 PGPPP-----PPPLPSTGPPPPPP 352
Score = 44.3 bits (103), Expect = 0.001
Identities = 46/185 (24%), Positives = 79/185 (42%), Gaps = 40/185 (21%)
Query: 1682 QDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQRP 1741
Q++L+++ E+E++++ + + + QE E++ + D Q+ + E + R +R
Sbjct: 188 QEQLERERQERERQERLERQERLERQERLERQER-LDRERQERQERERLERLERERQERE 246
Query: 1742 KSQVMN----VIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVAD 1797
+ + + ERR S S ++P+S +TP LN + G A
Sbjct: 247 RQEQLEREQLEWERERRIS-SAAAPASVETP------------------LNSVLGDSSAS 287
Query: 1798 VPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPP---------PLPSKTPPPP 1848
P L+ + + +LG PPPPPP LPP P P PPPP
Sbjct: 288 EPG---LQAASQPAETPSQQGIVLGPLAPPPPPP----LPPGPAQASVALPPPPGPPPPP 340
Query: 1849 PPKTT 1853
P +T
Sbjct: 341 PLPST 345
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 54.3 bits (129), Expect = 1e-06
Identities = 56/203 (27%), Positives = 77/203 (37%), Gaps = 37/203 (18%)
Query: 1672 LLPKKMHSRSQDKLDK-DDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILS 1730
LL +++ + + K +LEK+ +KE E + F + ++ S
Sbjct: 410 LLTERLRDAENESMAKIAELEKQLSQARKEL------ETLRERFSEST-AMGASRRPPEP 462
Query: 1731 ETISPLRPQRPKSQVMNVIGSERR-----------------FSVSPSSPSSQQTPPPVTP 1773
E P P RP + + V E + V+ ++PS P P P
Sbjct: 463 EKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVP 522
Query: 1774 RAKLSFSMQSSLELNGMTGADVADVPPPLPLKG----SVADYGNLMENQDLLGSPTPPPP 1829
S + + E A A PPP PL G A + L GSP PPP
Sbjct: 523 TGSPSPDLAPAAE-----PAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPA 577
Query: 1830 PPHQRHLPPPLPSKTPPPPPPKT 1852
PP LPPP P PPPPPP T
Sbjct: 578 PPLPGDLPPPPP---PPPPPPGT 597
Score = 46.2 bits (108), Expect = 3e-04
Identities = 33/108 (30%), Positives = 42/108 (38%), Gaps = 29/108 (26%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P PS Q+ PP P+A + G+ PPLP
Sbjct: 549 PGLPSPQEAPPSAPPQAP------------PLPGSPEPPPAPPLP--------------G 582
Query: 1819 DLLGSPTPPPPPPH-QRHLPPPLPSKTPPP--PPPKTTRKQTSVDSGI 1863
DL P PPPPPP +PPP P PPP PP R+ + + G+
Sbjct: 583 DLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGV 630
>gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]
Length = 2047
Score = 53.9 bits (128), Expect = 1e-06
Identities = 73/344 (21%), Positives = 134/344 (38%), Gaps = 24/344 (6%)
Query: 1276 LYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVKVI--- 1332
L ++ YF G ++E + K L E DY++L+ + K + + I+
Sbjct: 1686 LLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHR-DYKKLAAVHGKLQEAFTKIMHQSSGW 1744
Query: 1333 -RPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPN------AEKMK 1385
R YF VG+YG F L + F+Y+ + + RL + E +K
Sbjct: 1745 ERVFGTYFRVGFYGAHFGD-LDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIK 1803
Query: 1386 TTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIRK 1445
++P +S YIQ V+P D + +++ F R ++ F + P
Sbjct: 1804 DSNPVDKSKLDSQKAYIQITYVEPYFDT-----YELKDRVTYFDRNYGLRTFLFCTPFTP 1858
Query: 1446 GEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKIN 1505
+ E +T+ +T + P I V ++P+E AIE MQ ++
Sbjct: 1859 -DGRAHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELA 1917
Query: 1506 SMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLK 1565
+Q D + L M+L G V P V G + F + + E P+ KL+
Sbjct: 1918 FATEQDPPDAKM----LQMVLQGSVGPTVNQGPLEVAQVFLAE--IPEDPKLFRHHNKLR 1971
Query: 1566 DLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVE 1609
+ +R + + + +H +E + +L+E ++
Sbjct: 1972 LCFKDFCKKCEDALRKNKALIGPDQKEYHRELERNYCRLREALQ 2015
Score = 33.1 bits (74), Expect = 2.6
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 425 RNDIYVTLVQGDFDKGSKTTAKNVEVTVS-VYDEDGKRLEHVIFPGAGDEAISEYK---- 479
RN +YV +F + + +N+ V V + ED + VIF G + SE+
Sbjct: 548 RNLLYVYPHSLNFSS-RQGSVRNLAVRVQYMTGEDPSQALPVIF---GKSSCSEFTREAF 603
Query: 480 SVIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQ 519
+ + Y K P ++E K+ +P HL FTF H S Q
Sbjct: 604 TPVVYHNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSCQ 643
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 53.5 bits (127), Expect = 2e-06
Identities = 57/208 (27%), Positives = 76/208 (36%), Gaps = 36/208 (17%)
Query: 1675 KKMHSRSQDKL-----DKDDLEKEKKDKKKEKRNSKHQ------EIFEKEFKPTDISLQQ 1723
KKM S + KL +KD L EK+ EK++ + + E+ + + D +
Sbjct: 494 KKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEM 553
Query: 1724 SEAVILSETISPLRPQR-PKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKL----- 1777
+ + T+ P P R P + G P +P TPPP P
Sbjct: 554 ASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 613
Query: 1778 -SFSMQSSLELNGMTGADV-------ADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPP 1829
+ S L G T A +PPP PL V + L G PPP
Sbjct: 614 GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG----IPSPSSLPGGTAIPPP 669
Query: 1830 PPHQRHL-----PPPLPSKT--PPPPPP 1850
PP PPPLP PPPPPP
Sbjct: 670 PPLPGSARIPPPPPPLPGSAGIPPPPPP 697
Score = 45.8 bits (107), Expect = 4e-04
Identities = 34/94 (36%), Positives = 36/94 (38%), Gaps = 22/94 (23%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P S + PPP P L G G PPP PL G G
Sbjct: 670 PPLPGSARIPPPPPP-------------LPGSAGIP----PPPPPLPGEA---GMPPPPP 709
Query: 1819 DLLGSPTPPPPPPHQRH--LPPPLPSKTPPPPPP 1850
L G P PPPPP +PPP P PPPPP
Sbjct: 710 PLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 743
Score = 44.7 bits (104), Expect = 9e-04
Identities = 45/195 (23%), Positives = 72/195 (36%), Gaps = 47/195 (24%)
Query: 1669 LEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVI 1728
LE L ++ +R + +++ +E + + K ++ + K EK+ T+ ++E
Sbjct: 475 LEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQ 534
Query: 1729 LSETISPLRPQRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELN 1788
L+ ++ L + ++ S +V PS PS PP
Sbjct: 535 LTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA------------------ 576
Query: 1789 GMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPS----KT 1844
PPLP D G ++ G T PPPPP PPPLP +
Sbjct: 577 -----------PPLP-----GDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISS 620
Query: 1845 PP---------PPPP 1850
PP PPPP
Sbjct: 621 PPSLPGGTAISPPPP 635
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 53.5 bits (127), Expect = 2e-06
Identities = 57/208 (27%), Positives = 76/208 (36%), Gaps = 36/208 (17%)
Query: 1675 KKMHSRSQDKL-----DKDDLEKEKKDKKKEKRNSKHQ------EIFEKEFKPTDISLQQ 1723
KKM S + KL +KD L EK+ EK++ + + E+ + + D +
Sbjct: 503 KKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEM 562
Query: 1724 SEAVILSETISPLRPQR-PKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKL----- 1777
+ + T+ P P R P + G P +P TPPP P
Sbjct: 563 ASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 622
Query: 1778 -SFSMQSSLELNGMTGADV-------ADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPP 1829
+ S L G T A +PPP PL V + L G PPP
Sbjct: 623 GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG----IPSPSSLPGGTAIPPP 678
Query: 1830 PPHQRHL-----PPPLPSKT--PPPPPP 1850
PP PPPLP PPPPPP
Sbjct: 679 PPLPGSARIPPPPPPLPGSAGIPPPPPP 706
Score = 45.8 bits (107), Expect = 4e-04
Identities = 34/94 (36%), Positives = 36/94 (38%), Gaps = 22/94 (23%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P S + PPP P L G G PPP PL G G
Sbjct: 679 PPLPGSARIPPPPPP-------------LPGSAGIP----PPPPPLPGEA---GMPPPPP 718
Query: 1819 DLLGSPTPPPPPPHQRH--LPPPLPSKTPPPPPP 1850
L G P PPPPP +PPP P PPPPP
Sbjct: 719 PLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 752
Score = 44.7 bits (104), Expect = 9e-04
Identities = 45/195 (23%), Positives = 72/195 (36%), Gaps = 47/195 (24%)
Query: 1669 LEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVI 1728
LE L ++ +R + +++ +E + + K ++ + K EK+ T+ ++E
Sbjct: 484 LEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQ 543
Query: 1729 LSETISPLRPQRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELN 1788
L+ ++ L + ++ S +V PS PS PP
Sbjct: 544 LTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA------------------ 585
Query: 1789 GMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPS----KT 1844
PPLP D G ++ G T PPPPP PPPLP +
Sbjct: 586 -----------PPLP-----GDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISS 629
Query: 1845 PP---------PPPP 1850
PP PPPP
Sbjct: 630 PPSLPGGTAISPPPP 644
>gi|122937271 WAS protein homolog associated with actin, golgi
membranes and microtubules [Homo sapiens]
Length = 809
Score = 52.4 bits (124), Expect = 4e-06
Identities = 63/241 (26%), Positives = 94/241 (39%), Gaps = 43/241 (17%)
Query: 1621 LDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKMHSR 1680
L D + + + R S R A +SL S + + F L+ +SR
Sbjct: 450 LQDDKNLEVKELRRQCQQLESKRGRICAKRASLRSRKDQCKE-NHRFRLQQAEESIRYSR 508
Query: 1681 SQDKLD-KDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQ 1739
+ K D KE++ KKKE N + Q+ ++ D L QS
Sbjct: 509 QHHSIQMKRDKIKEEEQKKKEWINQERQKTLQRLRSFKDKRLAQS--------------- 553
Query: 1740 RPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVP 1799
V N GSE V+P+ PS + +S SS + G+ ++ +V
Sbjct: 554 -----VRNTSGSE---PVAPNLPSDLSQQMCLPASHAVSVIHPSSRKTRGVPLSEAGNVK 605
Query: 1800 PP--------LPLKG--SVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPP 1849
P +P++ V D + +++L P PPPPPP PPP P PPPPP
Sbjct: 606 SPKCQNCHGNIPVQVFVPVGDQTHSKSSEELSLPPPPPPPPP-----PPPPP---PPPPP 657
Query: 1850 P 1850
P
Sbjct: 658 P 658
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/99 (31%), Positives = 37/99 (37%), Gaps = 27/99 (27%)
Query: 1752 ERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADY 1811
++ + +SPSSP + PPP P PP P
Sbjct: 1945 DKLYPISPSSPETPPPPPPPPP----------------------LPPAPPQPSSMGPVKI 1982
Query: 1812 GNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPP 1850
N + PTPPPPPP PPP P PPPPPP
Sbjct: 1983 PNTVSTPLQAPPPTPPPPPP-----PPPPPPPPPPPPPP 2016
Score = 50.8 bits (120), Expect = 1e-05
Identities = 34/101 (33%), Positives = 38/101 (37%), Gaps = 23/101 (22%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P SPSS +TPPP P L + PP P N +
Sbjct: 1949 PISPSSPETPPPPPPPPPLPPA-------------------PPQPSSMGPVKIPNTVSTP 1989
Query: 1819 DLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKTTRKQTSV 1859
PTPPPPPP PPP P PPPPP + Q V
Sbjct: 1990 LQAPPPTPPPPPPP----PPPPPPPPPPPPPSAPPQVQLPV 2026
Score = 32.0 bits (71), Expect = 5.8
Identities = 33/122 (27%), Positives = 45/122 (36%), Gaps = 17/122 (13%)
Query: 1756 SVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPP-------LPLKGSV 1808
+ +P++ S T P+ P K S +D PP LPL +
Sbjct: 2331 AAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTS 2390
Query: 1809 ADYGNLMENQDLLGSPTPPPPPPHQRHL--PPPLPSKTPPPPPP---KTTRKQTSVDSGI 1863
+D Q P P P PP Q L PP S+TP P P T Q S+ +
Sbjct: 2391 SD-----PPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQL 2445
Query: 1864 VQ 1865
+Q
Sbjct: 2446 LQ 2447
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 51.2 bits (121), Expect = 9e-06
Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 17/91 (18%)
Query: 1772 TPRAKLSFSMQSSLELNGMTGADVADVP----------PPLPLK--GSVADYGNLMENQD 1819
TP +F+ LE G+ ++ P P +P+K V + M N+
Sbjct: 1954 TPVGCNAFAFNRHLEQKGLGEVSLSSAPHQLRLANMLSPNMPMKEGDEVGGTAHTMPNKA 2013
Query: 1820 LLGSPTPPPPPPHQRHLPPPLPSKTPPPPPP 1850
L+ P PPPPPP PPPL PPPPPP
Sbjct: 2014 LVHPPPPPPPPP-----PPPLALPPPPPPPP 2039
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 50.4 bits (119), Expect = 2e-05
Identities = 39/110 (35%), Positives = 47/110 (42%), Gaps = 20/110 (18%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMEN- 1817
P P TPPP+ P + LS + + +PPPLPL G E
Sbjct: 225 PPPPPPPPTPPPLPPASVLSDKAVKPQ----LAPLHLPPIPPPLPLLPPCGYPGLKAEPA 280
Query: 1818 ---QDLLGSPTPPPP-PPHQRHLP------PPLP-----SKTPPPPPPKT 1852
QD P PPPP PP+ P PPLP S+TPPP PPK+
Sbjct: 281 SPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKS 330
Score = 42.7 bits (99), Expect = 0.003
Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 26/102 (25%)
Query: 1758 SPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMEN 1817
+P P+ PPP+ P S +++ L V PP PL GNL
Sbjct: 173 APPPPTPPPPPPPLPPPLPSSSPIKTPL------------VSPPGPLTK-----GNL--- 212
Query: 1818 QDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKTTRKQTSV 1859
++ P P PPP PPP P TPPP PP + +V
Sbjct: 213 -PVVAPPVPCAPPP-----PPPPPPPTPPPLPPASVLSDKAV 248
Score = 42.0 bits (97), Expect = 0.006
Identities = 19/38 (50%), Positives = 19/38 (50%), Gaps = 2/38 (5%)
Query: 1824 PTPPPPPPHQRHLPPPLPSKTPPPPPPKTTRKQTSVDS 1861
P PPPPPP PPP P PPPPPP T S
Sbjct: 2 PVPPPPPPPLP--PPPPPLGAPPPPPPSAPPVSTDTSS 37
Score = 34.3 bits (77), Expect = 1.2
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 1798 VPPPLPLKGSVAD-YGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKT 1852
+PP P G+ ++ +G P PPPP P PPPLP P P KT
Sbjct: 145 IPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPP--PPPLPPPLPSSSPIKT 198
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 49.7 bits (117), Expect = 3e-05
Identities = 22/55 (40%), Positives = 26/55 (47%)
Query: 1796 ADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPP 1850
A +PPP PL + + P PPPPP LPPP + PPPPPP
Sbjct: 650 ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP 704
Score = 44.7 bits (104), Expect = 9e-04
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 17/109 (15%)
Query: 1744 QVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLE--LNGMTGADVADVPPP 1801
Q M + S ++ ++ P P + PPP P S S + G PPP
Sbjct: 632 QPMEGMASNQQKALPP--PPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPP 689
Query: 1802 LPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPP 1850
LP S G P PPPPPP PP P PP PPP
Sbjct: 690 LPPPSSA-------------GPPPPPPPPPLPNSPAPPNPGGPPPAPPP 725
>gi|61743948 abl-interactor 1 isoform d [Homo sapiens]
Length = 476
Score = 49.7 bits (117), Expect = 3e-05
Identities = 46/130 (35%), Positives = 55/130 (42%), Gaps = 19/130 (14%)
Query: 1732 TISPLRP-QRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLE---L 1787
TI P P P SQ + R + + SS SS TP FS Q + L
Sbjct: 265 TIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRR--TPSVTAQFSAQPHVNGGPL 322
Query: 1788 NGMTGADVADVPPPLP-------LKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPL 1840
+A PPP+P L G VA + EN + SPTPPPPPP +P
Sbjct: 323 YSQNSISIAPPPPPMPQLTPQIPLTGFVA---RVQEN--IADSPTPPPPPPPD-DIPMFD 376
Query: 1841 PSKTPPPPPP 1850
S PPPPPP
Sbjct: 377 DSPPPPPPPP 386
Score = 37.7 bits (86), Expect = 0.11
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 4 WVPTKREEKYGVAFYNYDARGADELSLQIGDTVHIL-ETYEGWYRGYTLRKKSKKGIFPA 62
W P EK VA Y+Y DELS G ++++ + +GWY G R G+FP
Sbjct: 410 WAPKNYIEKV-VAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNR---VTGLFPG 465
Query: 63 SYI 65
+Y+
Sbjct: 466 NYV 468
>gi|61743944 abl-interactor 1 isoform b [Homo sapiens]
Length = 481
Score = 49.7 bits (117), Expect = 3e-05
Identities = 46/130 (35%), Positives = 55/130 (42%), Gaps = 19/130 (14%)
Query: 1732 TISPLRP-QRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLE---L 1787
TI P P P SQ + R + + SS SS TP FS Q + L
Sbjct: 270 TIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRR--TPSVTAQFSAQPHVNGGPL 327
Query: 1788 NGMTGADVADVPPPLP-------LKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPL 1840
+A PPP+P L G VA + EN + SPTPPPPPP +P
Sbjct: 328 YSQNSISIAPPPPPMPQLTPQIPLTGFVA---RVQEN--IADSPTPPPPPPPD-DIPMFD 381
Query: 1841 PSKTPPPPPP 1850
S PPPPPP
Sbjct: 382 DSPPPPPPPP 391
Score = 37.7 bits (86), Expect = 0.11
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 4 WVPTKREEKYGVAFYNYDARGADELSLQIGDTVHIL-ETYEGWYRGYTLRKKSKKGIFPA 62
W P EK VA Y+Y DELS G ++++ + +GWY G R G+FP
Sbjct: 415 WAPKNYIEKV-VAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNR---VTGLFPG 470
Query: 63 SYI 65
+Y+
Sbjct: 471 NYV 473
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 49.7 bits (117), Expect = 3e-05
Identities = 60/263 (22%), Positives = 90/263 (34%), Gaps = 39/263 (14%)
Query: 1622 DDRRGSRPR-SMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKMHSR 1680
D R S P ++ ++P SRP + +S S S P P A P P MHS
Sbjct: 139 DSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSS 198
Query: 1681 SQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQR 1740
+++ ++ + P+ ++++ + P P R
Sbjct: 199 KAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSG--QSLAPPPPPYR 256
Query: 1741 PKSQVMNVIGS----------ERRFSVSPSSPSSQQ--TPPPVTPRAKLSFSMQSSLELN 1788
V N S +R S+ +P + PPP T + S +
Sbjct: 257 QPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPAR 316
Query: 1789 GMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRH--------LPPPL 1840
A PPP ++ D PPPPPP++ H PPP
Sbjct: 317 DPPSRGAAPPPPPPVIRNGARD--------------APPPPPPYRMHGSEPPSRGKPPPP 362
Query: 1841 PSKTP--PPPPPKTTRKQTSVDS 1861
PS+TP PPPPP + DS
Sbjct: 363 PSRTPAGPPPPPPPPLRNGHRDS 385
>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
[Homo sapiens]
Length = 355
Score = 49.3 bits (116), Expect = 4e-05
Identities = 38/120 (31%), Positives = 48/120 (40%), Gaps = 23/120 (19%)
Query: 1745 VMNVIGSERRFSVSPSSPSSQQT-PPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLP 1803
+ + IGS + ++P T PPP+ P FS S L P PLP
Sbjct: 219 IASKIGSNALRMIQSATPPPPTTRPPPIRP----PFSHPLSAHLPWY----FQPPPRPLP 270
Query: 1804 LKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKTTRKQTSVDSGI 1863
+ A P+PPPPPP PPP P PPPPPP T T + G+
Sbjct: 271 PRPPAAQPRP---------PPSPPPPPP-----PPPSPLPPPPPPPPPTPSSTTKLPQGL 316
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 49.3 bits (116), Expect = 4e-05
Identities = 47/179 (26%), Positives = 69/179 (38%), Gaps = 27/179 (15%)
Query: 1690 LEKEKKDKKKEKRNSKHQEIFEKEFKPTDI--SLQQSEAVILSETISPLR--PQRPKSQV 1745
L+ + K++ ++ HQ +PT +QQS+ SE P + PQ+P Q
Sbjct: 255 LDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQ- 313
Query: 1746 MNVIGSERRFSVSPSSP---------------SSQQTPPPVTPRAKLSFSMQSSLELNGM 1790
++ S PSSP + + PPP P+ + +
Sbjct: 314 QQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAH---- 369
Query: 1791 TGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPP 1849
D PPL A+ ++ DL PPP P H PPPLP + PPPPP
Sbjct: 370 ---PPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPP 425
Score = 37.7 bits (86), Expect = 0.11
Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 6/94 (6%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P PSS T T QS + G +PP + + ++
Sbjct: 422 PPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPN 481
Query: 1819 DLLGSPTPPPPPPHQRHLPPPLPSKTP--PPPPP 1850
P PP PPP PP +P TP PPPPP
Sbjct: 482 P----PPPPVPPPPASFPPPAIPPPTPGYPPPPP 511
Score = 34.7 bits (78), Expect = 0.89
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 13/60 (21%)
Query: 1799 PPPLPLKGSVADYGNLMENQDLLGSPTP---PPPPPHQRHLPPPLP-----SKTPPPPPP 1850
PPP P+ A + + PTP PPPP + + PPP P PP PPP
Sbjct: 482 PPPPPVPPPPASFP-----PPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPP 536
Score = 34.3 bits (77), Expect = 1.2
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 10/38 (26%)
Query: 1824 PTPPPP--------PPHQRHLPPPLPSKTP--PPPPPK 1851
P PPPP PP PPP P+ P PPPPP+
Sbjct: 486 PVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPR 523
Score = 33.5 bits (75), Expect = 2.0
Identities = 29/107 (27%), Positives = 41/107 (38%), Gaps = 20/107 (18%)
Query: 1759 PSSPSSQQTPPPVT----PRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNL 1814
P+ P+ PPP+ P S+ S + M+G + + +G YG L
Sbjct: 404 PAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGP--SYGAL 461
Query: 1815 ---------MENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKT 1852
+ + P PPPPP +PPP S PP PP T
Sbjct: 462 PPAYGPPAHLPYHPHVYPPNPPPPP-----VPPPPASFPPPAIPPPT 503
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 48.9 bits (115), Expect = 5e-05
Identities = 39/113 (34%), Positives = 45/113 (39%), Gaps = 29/113 (25%)
Query: 1738 PQRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVAD 1797
PQ P Q G+E P P + PPP P A + L L + GA +
Sbjct: 897 PQPPPLQ-----GTEMLPPPPPPLPGAGIPPPPPLPGAGI-------LPLPPLPGAGI-- 942
Query: 1798 VPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPP 1850
PPP PL G+ P PPP P LPPPLP PPPPP
Sbjct: 943 -PPPPPLPGAAI--------------PPPPPLPGAGIPLPPPLPGAGIPPPPP 980
Score = 45.1 bits (105), Expect = 7e-04
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P + PPP P A + L G A +PPP PL G+ +
Sbjct: 946 PPLPGAAIPPPPPLPGAGIPLPPP----LPG------AGIPPPPPLPGA-----GIPPPP 990
Query: 1819 DLLGSPTPPPPPPHQRHLPPP--LPSKTPPPPPP 1850
L G+ PPPPP +PPP LP PPPPP
Sbjct: 991 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P + PPP P A + L G A +PPP PL G+ +
Sbjct: 968 PPLPGAGIPPPPPLPGA----GIPPPPPLPG------AGIPPPPPLPGA-----GIPPPP 1012
Query: 1819 DLLGSPTPPPPPPHQRHLPPP--LPSKTPPPPPP 1850
L G+ PPPPP +PPP LP PPPPP
Sbjct: 1013 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1046
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P + PPP P A + L G A +PPP PL G+ +
Sbjct: 979 PPLPGAGIPPPPPLPGA----GIPPPPPLPG------AGIPPPPPLPGA-----GIPPPP 1023
Query: 1819 DLLGSPTPPPPPPHQRHLPPP--LPSKTPPPPPP 1850
L G+ PPPPP +PPP LP PPPPP
Sbjct: 1024 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1057
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P + PPP P A + L G A +PPP PL G+ +
Sbjct: 990 PPLPGAGIPPPPPLPGA----GIPPPPPLPG------AGIPPPPPLPGA-----GIPPPP 1034
Query: 1819 DLLGSPTPPPPPPHQRHLPPP--LPSKTPPPPPP 1850
L G+ PPPPP +PPP LP PPPPP
Sbjct: 1035 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1068
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P + PPP P A + L G A +PPP PL G+ +
Sbjct: 1001 PPLPGAGIPPPPPLPGA----GIPPPPPLPG------AGIPPPPPLPGA-----GIPPPP 1045
Query: 1819 DLLGSPTPPPPPPHQRHLPPP--LPSKTPPPPPP 1850
L G+ PPPPP +PPP LP PPPPP
Sbjct: 1046 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1079
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P + PPP P A + L G A +PPP PL G+ +
Sbjct: 1012 PPLPGAGIPPPPPLPGA----GIPPPPPLPG------AGIPPPPPLPGA-----GIPPPP 1056
Query: 1819 DLLGSPTPPPPPPHQRHLPPP--LPSKTPPPPPP 1850
L G+ PPPPP +PPP LP PPPPP
Sbjct: 1057 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1090
Score = 43.5 bits (101), Expect = 0.002
Identities = 32/92 (34%), Positives = 36/92 (39%), Gaps = 24/92 (26%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P + PPP P A + L G A +PPP PL G
Sbjct: 1067 PPLPGAGIPPPPPLPGA----GIPPPPPLPG------AGIPPPPPLPG------------ 1104
Query: 1819 DLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPP 1850
+G P PPP P PPPLP PPPPP
Sbjct: 1105 --VGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134
Score = 43.5 bits (101), Expect = 0.002
Identities = 32/92 (34%), Positives = 38/92 (41%), Gaps = 13/92 (14%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P + PPP PR + L G A +PPP PL G+ +
Sbjct: 1133 PPLPGAGIPPPPPLPRV----GIPPPPPLPG------AGIPPPPPLPGAGIPPPPPLPG- 1181
Query: 1819 DLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPP 1850
+G P PPP P PPPLP PPPPP
Sbjct: 1182 --VGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1211
Score = 43.1 bits (100), Expect = 0.003
Identities = 40/133 (30%), Positives = 49/133 (36%), Gaps = 28/133 (21%)
Query: 1738 PQRPKSQVMNVIGSERRFSVS-----PSSPSSQQTPPPVT------------PRAKLSFS 1780
PQ +++I S RR SV P+ SQ PPP P +S
Sbjct: 777 PQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTE 836
Query: 1781 MQSSLE---LNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLP 1837
Q+S E + + PPPLP S + L PPPPPP
Sbjct: 837 FQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGL--------GMVPPPPPPLPGMTV 888
Query: 1838 PPLPSKTPPPPPP 1850
P LPS P PPP
Sbjct: 889 PTLPSTAIPQPPP 901
Score = 42.4 bits (98), Expect = 0.004
Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P + PPP P A + L G+ +PPP PL G+ +
Sbjct: 1078 PPLPGAGIPPPPPLPGA----GIPPPPPLPGV------GIPPPPPLPGA-----GIPPPP 1122
Query: 1819 DLLGSPTPPPPPPHQRHL--PPPLPSKTPPPPPP 1850
L G+ PPPPP + PPPLP PPPPP
Sbjct: 1123 PLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/55 (41%), Positives = 27/55 (49%), Gaps = 3/55 (5%)
Query: 1796 ADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPP 1850
A +PPP PL G+ + +G P PPP P PPPLP PPPPP
Sbjct: 1127 AGIPPPPPLPGAGIPPPPPLPR---VGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
Score = 37.7 bits (86), Expect = 0.11
Identities = 32/100 (32%), Positives = 37/100 (37%), Gaps = 30/100 (30%)
Query: 1759 PSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQ 1818
P P + PPP P A + L G+ +PPP PL G
Sbjct: 1155 PPLPGAGIPPPPPLPGA----GIPPPPPLPGV------GIPPPPPLPG------------ 1192
Query: 1819 DLLGSPTPPPPPPHQRHLPPPLPS------KTPPPPPPKT 1852
+G P PPP P PPPLP PP PPP T
Sbjct: 1193 --VGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGT 1230
Score = 36.6 bits (83), Expect = 0.24
Identities = 19/54 (35%), Positives = 26/54 (48%)
Query: 1798 VPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPK 1851
+PPP PL G+ + + +P PP PPP PPPL + PP P+
Sbjct: 1195 IPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQ 1248
>gi|61743942 abl-interactor 1 isoform a [Homo sapiens]
Length = 508
Score = 48.9 bits (115), Expect = 5e-05
Identities = 47/136 (34%), Positives = 57/136 (41%), Gaps = 26/136 (19%)
Query: 1735 PLRPQRPKSQVMNVIGSE---------RRFSVSPSSPSSQQTPP-PVTPRAKLSFSMQSS 1784
PL P P S V+ GS R+ S S+ SS + TP FS Q
Sbjct: 289 PLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPH 348
Query: 1785 LE---LNGMTGADVADVPPPLP-------LKGSVADYGNLMENQDLLGSPTPPPPPPHQR 1834
+ L +A PPP+P L G VA + EN + SPTPPPPPP
Sbjct: 349 VNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVA---RVQEN--IADSPTPPPPPPPD- 402
Query: 1835 HLPPPLPSKTPPPPPP 1850
+P S PPPPPP
Sbjct: 403 DIPMFDDSPPPPPPPP 418
Score = 37.7 bits (86), Expect = 0.11
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 4 WVPTKREEKYGVAFYNYDARGADELSLQIGDTVHIL-ETYEGWYRGYTLRKKSKKGIFPA 62
W P EK VA Y+Y DELS G ++++ + +GWY G R G+FP
Sbjct: 442 WAPKNYIEKV-VAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNR---VTGLFPG 497
Query: 63 SYI 65
+Y+
Sbjct: 498 NYV 500
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 48.9 bits (115), Expect = 5e-05
Identities = 65/253 (25%), Positives = 98/253 (38%), Gaps = 24/253 (9%)
Query: 1625 RGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKMHSRSQDK 1684
R R RS RS + SR S A + TP P EP + + + K
Sbjct: 190 RRERKRSHSRSPRHRTKSRSPSPAPEKK---EKTPELPEPSVKVKEPSVQEATSTSDILK 246
Query: 1685 LDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQRPKSQ 1744
+ K + E K+ EK + K +E +++ +P S +S + S + S RP+R
Sbjct: 247 VPKPEPIPEPKEPSPEKNSKKEKE--KEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRS 304
Query: 1745 VMNVIGSERRFSVSPSSPSSQQTPP---PVTPRAKLSFS-----MQSSLELNGMTGADVA 1796
RR S ++TPP P PR + S S +SS L+G + + +
Sbjct: 305 RSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSS 364
Query: 1797 DVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPL---PSKTPPPPPP--- 1850
P K + + L +P PP +RH P P P KT P P
Sbjct: 365 SRSRSPPKKPPKRTSSPPRKTRRL----SPSASPPRRRHRPSPPATPPPKTRHSPTPQQS 420
Query: 1851 -KTTRKQTSVDSG 1862
+T + + SV G
Sbjct: 421 NRTRKSRVSVSPG 433
Score = 39.3 bits (90), Expect = 0.036
Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 52/222 (23%)
Query: 1675 KKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETIS 1734
+K+ S + DKD +KE+K+ +EKR K P+ S
Sbjct: 139 EKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP-----------RRRSS 187
Query: 1735 PLRPQRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGAD 1794
P+R +R +S + + S SP+ ++TP P K+ + S++ + +D
Sbjct: 188 PVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVK---EPSVQ-EATSTSD 243
Query: 1795 VADVPPPLPL---------KGSVAD---------YGNLMENQDLLGSPTPPPPPPHQRH- 1835
+ VP P P+ K S + + +++ S +P P +RH
Sbjct: 244 ILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHR 303
Query: 1836 ------LPPPLPS---------KTPP---PPPPKTTRKQTSV 1859
P PS +TPP PPPP+ R ++ V
Sbjct: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPV 345
Score = 37.7 bits (86), Expect = 0.11
Identities = 49/210 (23%), Positives = 76/210 (36%), Gaps = 42/210 (20%)
Query: 1668 ALEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNS-KHQEIFEKEFKPTDISLQQSEA 1726
A + + ++ + R + D + ++ KR+ K+ E+ + S S
Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
Query: 1727 VILSETISPLRPQRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLE 1786
ET R +R S + RR S SP+ P ++ P PR +
Sbjct: 535 KRQKETSPRGRRRRSPSPPP----TRRRRSPSPAPPPRRRRTPTPPPRRR---------- 580
Query: 1787 LNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPP--------PPPHQRHLPP 1838
PPP S Y ++ + SP+PPP PPP +R P
Sbjct: 581 ---------TPSPPPRRRSPSPRRYSPPIQRRY---SPSPPPKRRTASPPPPPKRRASPS 628
Query: 1839 PLP----SKTPPP---PPPKTTRKQTSVDS 1861
P P S +PPP P T R+ S+ S
Sbjct: 629 PPPKRRVSHSPPPKQRSSPVTKRRSPSLSS 658
Score = 33.1 bits (74), Expect = 2.6
Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 8/134 (5%)
Query: 1618 PSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKM 1677
PS RR S RS+ S P++ +P + S S ST P + P
Sbjct: 739 PSPQSVRRVSSSRSVSGS-PEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS 797
Query: 1678 HSRSQDKLDKDDLEKEKKDK--KKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETIS- 1734
R+ D+ +K+KKDK KK+K++ KH++ +++ + + A I + T +
Sbjct: 798 PPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTL 857
Query: 1735 ----PLRPQRPKSQ 1744
P+ PK +
Sbjct: 858 AQEEPVAAPEPKKE 871
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,821,120
Number of Sequences: 37866
Number of extensions: 3590433
Number of successful extensions: 38627
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 337
Number of HSP's successfully gapped in prelim test: 634
Number of HSP's that attempted gapping in prelim test: 24361
Number of HSP's gapped (non-prelim): 8066
length of query: 1865
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1748
effective length of database: 13,817,196
effective search space: 24152458608
effective search space used: 24152458608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.