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Search of human proteins with 4503337
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503337 dyskerin isoform 1 [Homo sapiens]
(514 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503337 dyskerin isoform 1 [Homo sapiens] 1019 0.0
gi|215599015 dyskerin isoform 2 [Homo sapiens] 1001 0.0
gi|21040257 TruB pseudouridine (psi) synthase homolog 1 [Homo sa... 67 4e-11
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 46 7e-05
gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens] 45 2e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 44 4e-04
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 44 5e-04
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 44 5e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 44 5e-04
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 44 5e-04
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 44 5e-04
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 44 5e-04
gi|4557509 cylicin 2 [Homo sapiens] 43 6e-04
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 42 0.001
gi|197927454 DEK oncogene isoform 2 [Homo sapiens] 42 0.001
gi|4503249 DEK oncogene isoform 1 [Homo sapiens] 42 0.001
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 41 0.003
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 40 0.004
gi|5803092 methionyl aminopeptidase 2 [Homo sapiens] 40 0.005
gi|28274705 family with sequence similarity 9, member A [Homo sa... 40 0.005
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 39 0.011
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 39 0.015
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 39 0.015
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 38 0.019
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 38 0.019
gi|4507525 translocation protein 1 [Homo sapiens] 38 0.019
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 38 0.025
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 38 0.025
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 38 0.025
gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens] 38 0.025
>gi|4503337 dyskerin isoform 1 [Homo sapiens]
Length = 514
Score = 1019 bits (2634), Expect = 0.0
Identities = 514/514 (100%), Positives = 514/514 (100%)
Query: 1 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 60
MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD
Sbjct: 1 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 60
Query: 61 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 120
KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH
Sbjct: 61 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 120
Query: 121 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 180
SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL
Sbjct: 121 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 180
Query: 181 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 240
FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG
Sbjct: 181 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 240
Query: 241 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 300
GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV
Sbjct: 241 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 300
Query: 301 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 360
MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH
Sbjct: 301 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 360
Query: 361 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYS 420
GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYS
Sbjct: 361 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYS 420
Query: 421 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK 480
ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK
Sbjct: 421 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK 480
Query: 481 AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 514
AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE
Sbjct: 481 AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 514
>gi|215599015 dyskerin isoform 2 [Homo sapiens]
Length = 509
Score = 1001 bits (2587), Expect = 0.0
Identities = 508/514 (98%), Positives = 509/514 (99%), Gaps = 5/514 (0%)
Query: 1 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 60
MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD
Sbjct: 1 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 60
Query: 61 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 120
KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH
Sbjct: 61 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 120
Query: 121 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 180
SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL
Sbjct: 121 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 180
Query: 181 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 240
FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG
Sbjct: 181 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 240
Query: 241 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 300
GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV
Sbjct: 241 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 300
Query: 301 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 360
MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH
Sbjct: 301 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 360
Query: 361 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYS 420
GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ+
Sbjct: 361 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQD----- 415
Query: 421 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK 480
ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK
Sbjct: 416 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK 475
Query: 481 AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 514
AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE
Sbjct: 476 AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 509
>gi|21040257 TruB pseudouridine (psi) synthase homolog 1 [Homo
sapiens]
Length = 349
Score = 67.0 bits (162), Expect = 4e-11
Identities = 62/258 (24%), Positives = 102/258 (39%), Gaps = 54/258 (20%)
Query: 89 TGFINLDKPSNPSSHEVV----------------AWIRRILRVEKTGHSGTLDPKVTGCL 132
+G + KP P+S E++ W +R + K GH GTLD G L
Sbjct: 69 SGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVL 128
Query: 133 IVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRA-----------------LET 175
+V I T+++ S S K Y I L A + R L+
Sbjct: 129 VVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQK 188
Query: 176 LTGALFQRPPLIAAVKRQ-LRVRTIYE-SKMIEYDPERRLGIFWVS-------------- 219
TG + Q PPL +A+K+ R+ T+ + +++E P R + ++ +S
Sbjct: 189 FTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVE 248
Query: 220 CEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDE 279
C G YIR+L +G L + EL R + G + ++H + + +W D+
Sbjct: 249 CGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALP-----EDKWTIDDIAQS 303
Query: 280 SYLRRVVYPLEKLLTSHK 297
++P E L K
Sbjct: 304 LEHCSSLFPAELALKKSK 321
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 46.2 bits (108), Expect = 7e-05
Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 25/131 (19%)
Query: 404 PTDSTPATWKQEYVDYSESAK---KEVVAEVVKAPQVVAEAAKTAKRKRESE-------- 452
PT+ P+ KQ D ES K K V+++ K +VV E AK A+ + E
Sbjct: 305 PTNLKPSKIKQR-ADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKA 363
Query: 453 SESDETPPAAP-----------QLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKK-- 499
ES E PP P + +K EK+K KDK K L+ + D KK
Sbjct: 364 KESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEI 423
Query: 500 KKKKKKAKEVE 510
KK++K+ K+ E
Sbjct: 424 KKERKELKKDE 434
>gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]
Length = 529
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/85 (34%), Positives = 42/85 (49%)
Query: 423 AKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAG 482
+KK + +V K ++ + AK AK K + E E +E + K+KKK K K K
Sbjct: 440 SKKRKIEQVDKEDEITEKKAKKAKIKVKVEEEEEEKVAEEEETSVKKKKKRGKKKHIKEE 499
Query: 483 LESGAEPGDGDSDTTKKKKKKKKAK 507
S EP + + +KKKKKK K
Sbjct: 500 PLSEEEPCTSTAIASPEKKKKKKKK 524
Score = 32.3 bits (72), Expect = 1.1
Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 13/86 (15%)
Query: 442 AKTAKRKRESESES-----DETPPAAP------QLIKKEKKKSKKDKKAK--AGLESGAE 488
AKT K + +SE ++ D T P Q+ K+++ KK KKAK +E E
Sbjct: 414 AKTEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEQVDKEDEITEKKAKKAKIKVKVEEEEE 473
Query: 489 PGDGDSDTTKKKKKKKKAKEVELVSE 514
+ + T KKKKK+ K+ + E
Sbjct: 474 EKVAEEEETSVKKKKKRGKKKHIKEE 499
Score = 29.3 bits (64), Expect = 9.0
Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
Query: 420 SESAKKEVVAEVVKAPQVVAEAAKTAKRKRE--------SESESDETPPAAPQLIKKEKK 471
++ AK +V E + +V E + K+K++ E S+E P + + EKK
Sbjct: 459 AKKAKIKVKVEEEEEEKVAEEEETSVKKKKKRGKKKHIKEEPLSEEEPCTSTAIASPEKK 518
Query: 472 KSKKDKK 478
K KK K+
Sbjct: 519 KKKKKKR 525
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 43.9 bits (102), Expect = 4e-04
Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 8/111 (7%)
Query: 400 KHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETP 459
K K T+ T T + E + E +KE E K + + +T KRK + E E
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK- 63
Query: 460 PAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 510
+K KKK +++++ + E E + + + +++KKKKK + E
Sbjct: 64 -------RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107
Score = 37.4 bits (85), Expect = 0.033
Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 5/73 (6%)
Query: 443 KTAKRKRESESESDETPPAAPQLIKKEKKKSK-----KDKKAKAGLESGAEPGDGDSDTT 497
K K+K++ E++ET + K+ K+K K K+K+ K + + + + +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 498 KKKKKKKKAKEVE 510
K+K+K+KK KE E
Sbjct: 61 KRKRKRKKKKEEE 73
Score = 35.0 bits (79), Expect = 0.16
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 443 KTAKRKRESES-----ESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTT 497
K K+K+E+E E++E + +K K+K K+ +K K E+ + +
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 498 KKKKKKKKAKEVELVSE 514
+K+K+KKK +E E E
Sbjct: 62 RKRKRKKKKEEEEREEE 78
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 43.5 bits (101), Expect = 5e-04
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 3/92 (3%)
Query: 418 DYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDK 477
+YS++ K + K + + K AK+ ++ESE + + +KK KK K K
Sbjct: 267 NYSQNNSKNYSLKYTKYTK--KDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKK 324
Query: 478 KAKAGLES-GAEPGDGDSDTTKKKKKKKKAKE 508
K ES AE GD + KK KKK K+
Sbjct: 325 DVKKDTESTDAESGDSKDERKDTKKDKKKLKK 356
Score = 35.4 bits (80), Expect = 0.13
Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 420 SESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKK- 478
SE KE + K + K + + E +++D P + KK++KK KKD K
Sbjct: 411 SELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKK 470
Query: 479 --AKAGLESGAEPGDGDSDTTKKKKKK 503
K + AE + +SD KK KK
Sbjct: 471 DDKKKDAKKNAESTEMESDLELKKDKK 497
Score = 32.7 bits (73), Expect = 0.81
Identities = 31/115 (26%), Positives = 47/115 (40%), Gaps = 6/115 (5%)
Query: 400 KHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETP 459
K+ K + + ++ S+ KK V + K V + T +S+ E +T
Sbjct: 290 KNAKKSSDAESEDSKDAKKDSKKVKKNVKKDD-KKKDVKKDTESTDAESGDSKDERKDTK 348
Query: 460 PAAPQLIKKEKKKSKKDKKAKAGLESG-AEPGDGDSDTTKKKK----KKKKAKEV 509
+L K +KKK K ESG A+ DS KK KKK AK++
Sbjct: 349 KDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKI 403
Score = 32.3 bits (72), Expect = 1.1
Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 17/130 (13%)
Query: 385 KASQKKLMIKQGLLD--KHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAA 442
K +KKL D K+ + TD+ K D K + K + + +
Sbjct: 348 KKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFST 407
Query: 443 KTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDS----DTTK 498
+ ES+ DE KK+KK SK D K +++ E D DS D+ K
Sbjct: 408 DSESELESKESQKDE---------KKDKKDSKTDN--KKSVKNDEESTDADSEPKGDSKK 456
Query: 499 KKKKKKKAKE 508
KK +KK K+
Sbjct: 457 GKKDEKKGKK 466
Score = 30.4 bits (67), Expect = 4.0
Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 8/120 (6%)
Query: 399 DKHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDET 458
DK TD+ + E ++S K + K + + +K +K++++ ++ T
Sbjct: 425 DKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAEST 484
Query: 459 PPAAPQLIKK------EKKKSKKD--KKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 510
+ +KK EKK SKKD K A+ ES D S T K K K + E
Sbjct: 485 EMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTE 544
Score = 30.0 bits (66), Expect = 5.3
Identities = 16/45 (35%), Positives = 22/45 (48%)
Query: 467 KKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVEL 511
KK+ KK K K AK ES D + KK K+KK + ++
Sbjct: 465 KKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDI 509
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 13/89 (14%)
Query: 420 SESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKA 479
S+ AK E E+ K V ++ + ++ + +SD+ KK+K+K +K KKA
Sbjct: 1334 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR--------KKDKEKKEKKKKA 1385
Query: 480 KAGLESGAEPGDGDSDTTKKKKKKKKAKE 508
K A D +S + KKKKKKKK E
Sbjct: 1386 KK-----ASTKDSESPSQKKKKKKKKTAE 1409
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 13/89 (14%)
Query: 420 SESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKA 479
S+ AK E E+ K V ++ + ++ + +SD+ KK+K+K +K KKA
Sbjct: 1373 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR--------KKDKEKKEKKKKA 1424
Query: 480 KAGLESGAEPGDGDSDTTKKKKKKKKAKE 508
K A D +S + KKKKKKKK E
Sbjct: 1425 KK-----ASTKDSESPSQKKKKKKKKTAE 1448
Score = 30.4 bits (67), Expect = 4.0
Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 12/105 (11%)
Query: 399 DKHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKA----PQVVAEAAKTAKRKRESESE 454
D GKP+ PA K V ES ++ K PQV A AKR ++ E E
Sbjct: 211 DVEGKPSVK-PAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEE 269
Query: 455 SD------ETPPAAPQLIKKEKKKSKKDKKAK-AGLESGAEPGDG 492
S+ E+ AP + + K S+K + + A + PG G
Sbjct: 270 SESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 13/89 (14%)
Query: 420 SESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKA 479
S+ AK E E+ K V ++ + ++ + +SD+ KK+K+K +K KKA
Sbjct: 1410 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR--------KKDKEKKEKKKKA 1461
Query: 480 KAGLESGAEPGDGDSDTTKKKKKKKKAKE 508
K A D +S + KKKKKKKK E
Sbjct: 1462 KK-----ASTKDSESPSQKKKKKKKKTAE 1485
Score = 30.4 bits (67), Expect = 4.0
Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 12/105 (11%)
Query: 399 DKHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKA----PQVVAEAAKTAKRKRESESE 454
D GKP+ PA K V ES ++ K PQV A AKR ++ E E
Sbjct: 211 DVEGKPSVK-PAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEE 269
Query: 455 SD------ETPPAAPQLIKKEKKKSKKDKKAK-AGLESGAEPGDG 492
S+ E+ AP + + K S+K + + A + PG G
Sbjct: 270 SESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 13/89 (14%)
Query: 420 SESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKA 479
S+ AK E E+ K V ++ + ++ + +SD+ KK+K+K +K KKA
Sbjct: 1333 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR--------KKDKEKKEKKKKA 1384
Query: 480 KAGLESGAEPGDGDSDTTKKKKKKKKAKE 508
K A D +S + KKKKKKKK E
Sbjct: 1385 KK-----ASTKDSESPSQKKKKKKKKTAE 1408
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 13/89 (14%)
Query: 420 SESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKA 479
S+ AK E E+ K V ++ + ++ + +SD+ KK+K+K +K KKA
Sbjct: 1372 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR--------KKDKEKKEKKKKA 1423
Query: 480 KAGLESGAEPGDGDSDTTKKKKKKKKAKE 508
K A D +S + KKKKKKKK E
Sbjct: 1424 KK-----ASTKDSESPSQKKKKKKKKTAE 1447
Score = 30.4 bits (67), Expect = 4.0
Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 12/105 (11%)
Query: 399 DKHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKA----PQVVAEAAKTAKRKRESESE 454
D GKP+ PA K V ES ++ K PQV A AKR ++ E E
Sbjct: 211 DVEGKPSVK-PAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEE 269
Query: 455 SD------ETPPAAPQLIKKEKKKSKKDKKAK-AGLESGAEPGDG 492
S+ E+ AP + + K S+K + + A + PG G
Sbjct: 270 SESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 43.1 bits (100), Expect = 6e-04
Identities = 36/117 (30%), Positives = 55/117 (47%), Gaps = 22/117 (18%)
Query: 393 IKQGLLD-KHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRES 451
+KQG D K GK + K+E +D + +KK K A++ ++S
Sbjct: 134 LKQGKKDSKKGKDIEKG----KEEKLDAKKDSKK---------------GKKDAEKGKDS 174
Query: 452 ESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKE 508
+ES++ A + KK+KK S K K + ES E G + D+ K KK KK K+
Sbjct: 175 ATESEDEKGGAKKDNKKDKKDSNKGK--DSATESEGEKGGTEKDSKKGKKDSKKGKD 229
Score = 35.0 bits (79), Expect = 0.16
Identities = 30/114 (26%), Positives = 45/114 (39%), Gaps = 8/114 (7%)
Query: 403 KPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAA 462
KPT + K + + K + + + + K +K+ ++ E +E A
Sbjct: 100 KPTRTVEVDSKAAEIG-KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDA- 157
Query: 463 PQLIKKEKKKSKKD--KKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 514
KK+ KK KKD K + ES E G D K KK K K+ SE
Sbjct: 158 ----KKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESE 207
Score = 30.0 bits (66), Expect = 5.3
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 12/97 (12%)
Query: 418 DYSESAKKEVVAEVVKAPQVVAEAAKT---AKRKRESESESDETPPA---APQLIKKEKK 471
D S+ AKK+ E+ K + + + T +K + ES+ D T A A + +KE
Sbjct: 255 DESKDAKKDA-KEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESA 313
Query: 472 KSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKE 508
SKKD K A + D+ KK +KK AK+
Sbjct: 314 DSKKDAKKNA-----KKDAKKDAKKNAKKDEKKDAKK 345
Score = 29.6 bits (65), Expect = 6.9
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 16/92 (17%)
Query: 393 IKQGLLDKHGKPT----DSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRK 448
IK+G DK KP+ DS K+ D ++ AKK + K A++ K AK+
Sbjct: 267 IKKGKKDKK-KPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKES---ADSKKDAKKN 322
Query: 449 RESESESDETPPAAPQLIKKEKKKSKKDKKAK 480
+ +++ D K KK KKD K K
Sbjct: 323 AKKDAKKDAK--------KNAKKDEKKDAKKK 346
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 42.4 bits (98), Expect = 0.001
Identities = 38/136 (27%), Positives = 64/136 (47%), Gaps = 12/136 (8%)
Query: 386 ASQKKLMIKQGLLDKHGKPTDSTPATWKQEYV---DYSESAKKEVVAEVVKAPQVVAEAA 442
+S +K+ K +++++ + A KQE V DY+E+AK A++ +AP E
Sbjct: 40 SSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGE-AKITEAPASEKEIV 98
Query: 443 KTAKRKRESESESD-ETPPAAPQLIKKEKKKSKKDK------KAKAGLESGAEPGDGDSD 495
+ + E +E E A +K E++ K+D+ K +AG E E G+ D
Sbjct: 99 EVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGK 158
Query: 496 TTKK-KKKKKKAKEVE 510
K +K + AKE E
Sbjct: 159 EDKNGNEKGEDAKEKE 174
Score = 29.6 bits (65), Expect = 6.9
Identities = 23/103 (22%), Positives = 41/103 (39%), Gaps = 8/103 (7%)
Query: 399 DKHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDET 458
+K G+ ++ A K E D E + + + EA K K ++ E ++
Sbjct: 110 EKGGEKKEAVAAEVKNEEEDQKEDEEDQ--------NEEKGEAGKEDKDEKGEEDGKEDK 161
Query: 459 PPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKK 501
KEK+ KK + K E G E G+ + + +K+
Sbjct: 162 NGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKE 204
>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
Length = 341
Score = 42.0 bits (97), Expect = 0.001
Identities = 36/117 (30%), Positives = 55/117 (47%), Gaps = 12/117 (10%)
Query: 402 GKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKT----AKRKRES----ES 453
GKP + T + S+ A+ K P+++++ + + K K ES +
Sbjct: 156 GKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDK 215
Query: 454 ESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 510
ES+E PP + K+EK K K K+K ++S A DS TTKK + K KE E
Sbjct: 216 ESEEEPPK--KTAKREKPKQKATSKSKKSVKS-ANVKKADSSTTKKNQNSSK-KESE 268
>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
Length = 375
Score = 42.0 bits (97), Expect = 0.001
Identities = 36/117 (30%), Positives = 55/117 (47%), Gaps = 12/117 (10%)
Query: 402 GKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKT----AKRKRES----ES 453
GKP + T + S+ A+ K P+++++ + + K K ES +
Sbjct: 190 GKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDK 249
Query: 454 ESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 510
ES+E PP + K+EK K K K+K ++S A DS TTKK + K KE E
Sbjct: 250 ESEEEPPK--KTAKREKPKQKATSKSKKSVKS-ANVKKADSSTTKKNQNSSK-KESE 302
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 40.8 bits (94), Expect = 0.003
Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 13/140 (9%)
Query: 371 MERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYSESAKKEVVAE 430
+E D P+ L +A ++++GL +K G T A K+ +K V +
Sbjct: 1299 VETDKKPQGKQLQTRADYLLKLLRKGL-EKKGAVTGGEEAKLKK---------RKPRVKK 1348
Query: 431 VVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIK---KEKKKSKKDKKAKAGLESGA 487
K P++ E R S++ S+E L K K+K+K K++K+ K S
Sbjct: 1349 ENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSR 1408
Query: 488 EPGDGDSDTTKKKKKKKKAK 507
+ +GD + K K KK+K K
Sbjct: 1409 KDKEGDKERKKSKDKKEKPK 1428
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 40.4 bits (93), Expect = 0.004
Identities = 40/154 (25%), Positives = 64/154 (41%), Gaps = 19/154 (12%)
Query: 374 DTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTD------STPATWKQEYVDY---SESAK 424
D + G PKA +K + K G K K +D S ++ + VDY S+
Sbjct: 222 DASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSS 281
Query: 425 KEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKK----KSKKDKKAK 480
+E KAPQ ++ SE +E PP + ++EKK + KK +K
Sbjct: 282 QEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDS 341
Query: 481 AGLESGAEPGDGDSDTT------KKKKKKKKAKE 508
+ +E D DS+ + KKK K+ ++
Sbjct: 342 SEESDSSEESDIDSEASSALFMAKKKTPPKRERK 375
Score = 30.8 bits (68), Expect = 3.1
Identities = 28/114 (24%), Positives = 54/114 (47%), Gaps = 14/114 (12%)
Query: 415 EYVDYSESAKKEVVAEVVKAPQVVAEAA--KTAKRKRESESESD-------ETPPAAPQL 465
E D SE +++E E K + +A + KR+++S ESD ++ ++
Sbjct: 303 EQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALF 362
Query: 466 IKKEKKKSKKDKKAKAGLESG-AEPG----DGDSDTTKKKKKKKKAKEVELVSE 514
+ K+K K+++K G G + PG +G S ++ + K ++ + VSE
Sbjct: 363 MAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSE 416
>gi|5803092 methionyl aminopeptidase 2 [Homo sapiens]
Length = 478
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 9/86 (10%)
Query: 434 APQVVAEAAKTAKRKRES--------ESESDETPPAAPQLIKKEKKKSK-KDKKAKAGLE 484
A EAAK +RK++ E E D+ A+ + ++ ++S +DK+ E
Sbjct: 27 AASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDE 86
Query: 485 SGAEPGDGDSDTTKKKKKKKKAKEVE 510
G GDG + KKKKKKK+ +V+
Sbjct: 87 DGDGDGDGATGKKKKKKKKKRGPKVQ 112
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 40.0 bits (92), Expect = 0.005
Identities = 33/154 (21%), Positives = 75/154 (48%), Gaps = 13/154 (8%)
Query: 361 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATW---KQEYV 417
G+ AK + + +++ Y + +A +KK + +Q +H + + + KQ+
Sbjct: 130 GLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDD 189
Query: 418 DYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDK 477
+ E+ AE A + A AA+ + E E E +E ++EK++ +++
Sbjct: 190 EAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEE---------EEEKEEEEEEG 240
Query: 478 KAKAGLESGAE-PGDGDSDTTKKKKKKKKAKEVE 510
+ + G E G E G G+ + T++++++++ +E E
Sbjct: 241 EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEE 274
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 38.9 bits (89), Expect = 0.011
Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 11/129 (8%)
Query: 384 PKASQKKLMIKQGLL------DKHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQV 437
PKA+++K + K+ + ++ KP + + E KKE V + VK
Sbjct: 630 PKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKK--- 686
Query: 438 VAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTT 497
E K K++ + E + + P + +KKE+KK K ++ + E P D +T
Sbjct: 687 --EIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSST 744
Query: 498 KKKKKKKKA 506
+ KK A
Sbjct: 745 PLSEAKKPA 753
Score = 38.1 bits (87), Expect = 0.019
Identities = 38/152 (25%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 367 KRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYSESAKKE 426
K +M + P K P ++K++ K+ +P+ +++ D A KE
Sbjct: 583 KEKVMVKKDKPIKTETKPSVTEKEVPSKE-------EPSPVKAEVAEKQATDVKPKAAKE 635
Query: 427 VVAEVVKAPQVVAEAAKTAKRKRESE--SESDETP------PAAPQLIKKEKKKSKKDKK 478
V K +V E K K K + E + D+TP P ++ K+ KK+ KK++K
Sbjct: 636 KT--VKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEK 693
Query: 479 AKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 510
+ E E + KK++KK+ K+ E
Sbjct: 694 KEPKKEVKKETPPKEVKKEVKKEEKKEVKKEE 725
Score = 33.9 bits (76), Expect = 0.36
Identities = 38/152 (25%), Positives = 59/152 (38%), Gaps = 18/152 (11%)
Query: 367 KRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDS-----TPATWKQEYVDYSE 421
K V + D P K PK + K +K+ + + K TP K+ + +
Sbjct: 658 KEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPP--KEVKKEVKK 715
Query: 422 SAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKA 481
KKEV E + + + + K AK+ SE+ + P++ KKE+ K A
Sbjct: 716 EEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGK 775
Query: 482 GLESGAEPGDGDSDTTKKKKKKKKAKEVELVS 513
E G K K KK+ K E V+
Sbjct: 776 PKEKG-----------KIKVIKKEGKAAEAVA 796
Score = 29.3 bits (64), Expect = 9.0
Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 14/108 (12%)
Query: 406 DSTPATWKQEYVDYSESAK-KEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQ 464
+ TP K +V+ + KE V +VK + + K + ++E S+ + +P A
Sbjct: 563 EETPEVTKVNHVEKPPKVESKEKV--MVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEV 620
Query: 465 LIKKE---KKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEV 509
K+ K K+ K+K K E+ +P D KK++K+K KEV
Sbjct: 621 AEKQATDVKPKAAKEKTVKK--ETKVKPED------KKEEKEKPKKEV 660
Score = 29.3 bits (64), Expect = 9.0
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
Query: 430 EVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEP 489
EV K P AE+ E E E ++TP + K+ +K + AG E +E
Sbjct: 883 EVTKGP---AESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSET 939
Query: 490 GDGDSDTTKKKKKKKKAKEVE 510
GD ++K + ++A+E E
Sbjct: 940 GD-----YEEKAETEEAEEPE 955
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 38.5 bits (88), Expect = 0.015
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 4/103 (3%)
Query: 412 WKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEK- 470
WK+E + E + K + E K+ + S S SD + ++ + +K
Sbjct: 59 WKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQ 118
Query: 471 ---KKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 510
+K KK++ K+ S +E D+ KKKKK K E E
Sbjct: 119 GKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKE 161
Score = 33.9 bits (76), Expect = 0.36
Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 2/98 (2%)
Query: 411 TWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEK 470
TW +E + E KK A ++ K ++ RE E+ Q KKEK
Sbjct: 30 TW-EEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEK 88
Query: 471 KKS-KKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAK 507
KKS + + + +S + D + + K+ K++KK K
Sbjct: 89 KKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKK 126
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 38.5 bits (88), Expect = 0.015
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 4/103 (3%)
Query: 412 WKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEK- 470
WK+E + E + K + E K+ + S S SD + ++ + +K
Sbjct: 69 WKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQ 128
Query: 471 ---KKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 510
+K KK++ K+ S +E D+ KKKKK K E E
Sbjct: 129 GKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKE 171
Score = 33.9 bits (76), Expect = 0.36
Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 2/98 (2%)
Query: 411 TWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEK 470
TW +E + E KK A ++ K ++ RE E+ Q KKEK
Sbjct: 40 TW-EEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEK 98
Query: 471 KKS-KKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAK 507
KKS + + + +S + D + + K+ K++KK K
Sbjct: 99 KKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKK 136
>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
Length = 597
Score = 38.1 bits (87), Expect = 0.019
Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 13/110 (11%)
Query: 402 GKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAP-QVVAEAAKTAKRKRESESESDETPP 460
GK A W+ Y DY++ ++ + V+K V E + + + SD
Sbjct: 2 GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61
Query: 461 AAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVE 510
+ KK+KKKS+K+K D + K+K++KK+ +E E
Sbjct: 62 RHKEKKKKKKKKSEKEKHLD------------DEERRKRKEEKKRKRERE 99
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 38.1 bits (87), Expect = 0.019
Identities = 43/158 (27%), Positives = 65/158 (41%), Gaps = 25/158 (15%)
Query: 372 ERDTYPRKWGLGPKASQKKLMI------------KQGLLDKHGKPTDSTPATWKQEYVD- 418
+++ P+K PK +KK K+ DK PT A K E +
Sbjct: 860 KKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED 919
Query: 419 -----YSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKS 473
+E AKKE K P AE + A K++++ E + P P K + K+
Sbjct: 920 AKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP----KTEAKA 975
Query: 474 KKDKK--AKAGLESGAEPGDGDSDTTKK-KKKKKKAKE 508
K+D K +K + AE + S T +K K +KA E
Sbjct: 976 KEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013
Score = 36.2 bits (82), Expect = 0.073
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
Query: 408 TPATWKQEYVDYSESAKKEVVA-EVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQL- 465
+P K + +++ +KE+ E VK+P E + K K + +E PA P+
Sbjct: 795 SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTE 854
Query: 466 IKKEKKKSKKDKK--AKAGLESGAEPGDGDSDTTKKKKKKKKAKEVELV 512
KK+ KK + KK K +E EP +K + KK++A++ + V
Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKV 903
Score = 32.7 bits (73), Expect = 0.81
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 408 TPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIK 467
+P + + + ++S KE KA V E AK+ ++ + E +TP A +K
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVK 741
Query: 468 KEKK---KSKKDKKAK 480
+E K K+K +KAK
Sbjct: 742 EEAKSPEKAKSPEKAK 757
Score = 31.2 bits (69), Expect = 2.4
Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 13/106 (12%)
Query: 406 DSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQL 465
+ PAT K E + +KKE +AP+ A K ++K + + E+ A +
Sbjct: 845 EKAPATPKTEE---KKDSKKE------EAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE 895
Query: 466 IKKEKKKS---KKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKE 508
++KKK +K+ AK ++ A+P + ++ KK+ KAKE
Sbjct: 896 EAEDKKKVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEPDDAKAKE 940
Score = 30.4 bits (67), Expect = 4.0
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 420 SESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAA--PQLIKK-EKKKSKKD 476
++S KE +A V E AK+ + E T A P+ K EK+++K
Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP 663
Query: 477 KKAKAGLESGAE-PGDGDSDTTKKKKKKKKAK 507
+KAK+ +++ A+ P S + K +KAK
Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
Score = 30.0 bits (66), Expect = 5.3
Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 404 PTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEA-AKTAKRKRESESESDETPPAA 462
P + + K+ E AK A+ + + + A K+ ++ + E ++PP A
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564
Query: 463 PQLIKKEKK---KSKKDKKAKA-GLESGAEPGDGDSDTTKKKKKKKKAK 507
K+E K + K +KAK+ E P + S K K++AK
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613
>gi|4507525 translocation protein 1 [Homo sapiens]
Length = 399
Score = 38.1 bits (87), Expect = 0.019
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
Query: 411 TWKQEYVDY-SESAKKEVVAEVVKAPQVVAEA-AKTAKRKRESESESDETPPAAPQLIKK 468
T ++ VDY + KK+ +K ++ + K K K ++ES +E + + IK
Sbjct: 73 TTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKD 132
Query: 469 EKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAK 507
EK K +K+KK E + + T KKK+ KKK K
Sbjct: 133 EKTKKEKEKKKDGEKEESKK--EETPGTPKKKETKKKFK 169
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 37.7 bits (86), Expect = 0.025
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 11/108 (10%)
Query: 413 KQEYVDYSESAKKEVVAEVVKAPQVVAE------AAKTAKRKRESESESDETPPAAPQLI 466
K+E D E ++ E V P E +T K + E E +
Sbjct: 210 KEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPT 269
Query: 467 KKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 514
K+K K + D++A+AG+++ D D D +K +KK +++ +L ++
Sbjct: 270 PKQKLKEEPDREARAGVQA-----DEDEDGDEKDEKKHRSQPKDLAAK 312
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 37.7 bits (86), Expect = 0.025
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 11/108 (10%)
Query: 413 KQEYVDYSESAKKEVVAEVVKAPQVVAE------AAKTAKRKRESESESDETPPAAPQLI 466
K+E D E ++ E V P E +T K + E E +
Sbjct: 194 KEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPT 253
Query: 467 KKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 514
K+K K + D++A+AG+++ D D D +K +KK +++ +L ++
Sbjct: 254 PKQKLKEEPDREARAGVQA-----DEDEDGDEKDEKKHRSQPKDLAAK 296
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 37.7 bits (86), Expect = 0.025
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 446 KRKRESESESDETPPAAPQLIKKEKKKSK---KDKKAKAGLESGAEPGDGDSDTTKKKKK 502
K +R + + E P A K+KKKSK +D+ ++ +S D+D + KKK
Sbjct: 1177 KARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDSRHQQDSDLSAACSDADLHRHKKK 1236
Query: 503 KKKAKEVELVSE 514
KKK K SE
Sbjct: 1237 KKKKKRHSRKSE 1248
>gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens]
Length = 322
Score = 37.7 bits (86), Expect = 0.025
Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 418 DYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDK 477
+Y E + +V + Q A+T SES DE P + KKEKKK KK+K
Sbjct: 114 NYRAPKDSEEIDDVTRQLQEKGCGARTPSPSL-SESSEDEKPTKKHKKDKKEKKKKKKEK 172
Query: 478 KAKAGLESGAEPGDGDSDTTKKKKKK 503
+ KA E AE S K K+K
Sbjct: 173 E-KADREVQAEQPSSSSPRRKTVKEK 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,485,917
Number of Sequences: 37866
Number of extensions: 870462
Number of successful extensions: 7844
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 123
Number of HSP's successfully gapped in prelim test: 223
Number of HSP's that attempted gapping in prelim test: 5578
Number of HSP's gapped (non-prelim): 1643
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.