Guide to the Human Genome
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Search of human proteins with 4502703

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502703 cell division cycle 6 protein [Homo sapiens]
         (560 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502703 cell division cycle 6 protein [Homo sapiens]              1103   0.0  
gi|31795544 origin recognition complex, subunit 1 [Homo sapiens]      170   3e-42
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             42   0.001
gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]           37   0.037
gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]           37   0.037
gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]             37   0.037
gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]            37   0.037
gi|32454748 origin recognition complex subunit 4 [Homo sapiens]        37   0.063
gi|32454746 origin recognition complex subunit 4 [Homo sapiens]        37   0.063
gi|32454750 origin recognition complex subunit 4 [Homo sapiens]        37   0.063
gi|169234742 NACHT and WD repeat domain containing 1 [Homo sapiens]    36   0.11 
gi|5453593 adenylyl cyclase-associated protein 2 [Homo sapiens]        35   0.24 
gi|32528306 replication factor C large subunit [Homo sapiens]          32   1.2  
gi|4758646 kinesin family member 3B [Homo sapiens]                     32   1.2  
gi|14043024 BCL2-associated athanogene 3 [Homo sapiens]                32   1.2  
gi|31881687 replication factor C 4 [Homo sapiens]                      32   1.2  
gi|4506491 replication factor C 4 [Homo sapiens]                       32   1.2  
gi|33667040 NLR family, pyrin domain containing 8 [Homo sapiens]       32   1.5  
gi|75677353 AAA-ATPase  TOB3 [Homo sapiens]                            32   1.5  
gi|148664197 coiled-coil domain containing 40 [Homo sapiens]           32   1.5  
gi|38788274 bromodomain PHD finger transcription factor isoform ...    32   2.0  
gi|167621456 kinase suppressor of ras 2 [Homo sapiens]                 32   2.0  
gi|19718796 RAD17 homolog isoform 1 [Homo sapiens]                     31   2.6  
gi|19718794 RAD17 homolog isoform 1 [Homo sapiens]                     31   2.6  
gi|19718792 RAD17 homolog isoform 1 [Homo sapiens]                     31   2.6  
gi|19718784 RAD17 homolog isoform 1 [Homo sapiens]                     31   2.6  
gi|4506383 RAD17 homolog isoform 1 [Homo sapiens]                      31   2.6  
gi|19718786 RAD17 homolog isoform 2 [Homo sapiens]                     31   2.6  
gi|157057547 Fc receptor-like 6 [Homo sapiens]                         31   2.6  
gi|223555989 hypothetical protein LOC51101 [Homo sapiens]              31   3.4  

>gi|4502703 cell division cycle 6 protein [Homo sapiens]
          Length = 560

 Score = 1103 bits (2852), Expect = 0.0
 Identities = 560/560 (100%), Positives = 560/560 (100%)

Query: 1   MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLG 60
           MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLG
Sbjct: 1   MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLG 60

Query: 61  DDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKI 120
           DDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKI
Sbjct: 61  DDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKI 120

Query: 121 LSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD 180
           LSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD
Sbjct: 121 LSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD 180

Query: 181 VIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQ 240
           VIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQ
Sbjct: 181 VIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQ 240

Query: 241 AVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTL 300
           AVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTL
Sbjct: 241 AVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTL 300

Query: 301 FEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLN 360
           FEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLN
Sbjct: 301 FEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLN 360

Query: 361 QVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSP 420
           QVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSP
Sbjct: 361 QVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSP 420

Query: 421 SEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEV 480
           SEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEV
Sbjct: 421 SEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEV 480

Query: 481 TLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKE 540
           TLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKE
Sbjct: 481 TLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKE 540

Query: 541 IEHALKDKALIGNILATGLP 560
           IEHALKDKALIGNILATGLP
Sbjct: 541 IEHALKDKALIGNILATGLP 560


>gi|31795544 origin recognition complex, subunit 1 [Homo sapiens]
          Length = 861

 Score =  170 bits (431), Expect = 3e-42
 Identities = 129/471 (27%), Positives = 228/471 (48%), Gaps = 52/471 (11%)

Query: 99  DNQLTIKSPSKRELAKVHQNKILSSVRKSQEITTNSEQRCPLKKESACVR-------LFK 151
           D +     P  R   +     + SS++ S    T   ++    +   C         L  
Sbjct: 422 DEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAA 481

Query: 152 QE-GTCYQQAKLVLN-TAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKT 209
           QE  +  ++A+L L+ +AVP+ LP RE+E   I NF+   +     G +Y+SG PGTGKT
Sbjct: 482 QEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKT 541

Query: 210 ACLSRILQDLKK-----ELKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAGKDMM 264
           A +  +++ L++     ++  F+ I +N M L     V+  I Q++  ++ +     ++ 
Sbjct: 542 ATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL- 600

Query: 265 RKLEKHMTAEKGPM--IVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDL 322
             L K       P    VL++DE+D L +  QD++Y LF+WP    + LV++ IANT+DL
Sbjct: 601 --LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDL 658

Query: 323 TDRIL-----PRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCA 377
            +RI+      RL     C      F PYT +Q+  IL+ RL  +   +  ++ A+Q  A
Sbjct: 659 PERIMMNRVSSRLGLTRMC------FQPYTYSQLQQILRSRLKHL---KAFEDDAIQLVA 709

Query: 378 RKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQV 437
           RKV+A+SGD R+ LD+CRRA EI E   +                   P   GL+ I+  
Sbjct: 710 RKVAALSGDARRCLDICRRATEICEFSQQK------------------PDSPGLVTIAHS 751

Query: 438 ISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQ 497
           +  VD    +      ++S  L+Q  L  +++   R+  ++E T  ++Y  +  +CR + 
Sbjct: 752 MEAVDEMFSSSYITAIKNSSVLEQSFL-RAILAEFRRSGLEEATFQQIYSQHVALCRMEG 810

Query: 498 VAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDK 548
           +     SE +++   L +  +L ++ ++   L +V   + + ++ +ALKD+
Sbjct: 811 LPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE 861


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 27/171 (15%)

Query: 24  NKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLGDDNLCN-----TPHLPPCSPPKQ 78
           +KA  +++ K E   V     S ++ A P   +   G     N     + HLPP  PPK 
Sbjct: 355 SKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPP--PPKL 412

Query: 79  GKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELA---------KVHQNKILSSVRKSQE 129
             +++ PP    + GR   F        PSK+++A         +  Q++I ++V ++++
Sbjct: 413 LAQQHPPPDRQAVPGRPGPF--------PSKQQVADEDEIWKQRRRQQSEISAAVERARK 464

Query: 130 ITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD 180
                E+R   ++++AC    K+     ++  ++     P+ +  RERE +
Sbjct: 465 RREEEERRMEEQRKAACAEKLKR---LDEKLGILEKQPSPEEIREREREKE 512


>gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]
          Length = 319

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 55/219 (25%), Positives = 91/219 (41%), Gaps = 44/219 (20%)

Query: 179 MDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRT 238
           +  I+ F+ E     +   L L G PGTGKT+ +    + L K+ K F +++L       
Sbjct: 20  LSTIQKFINED----RLPHLLLYGPPGTGKTSTILACAKQLYKD-KEFGSMVL------- 67

Query: 239 AQAVFPAIAQEICQEEVSRPAGKDMMR----KLEKHMTAEKGPMIVLVLDEMDQLDSKGQ 294
                        +   S   G D++R          T  K    +++LDE D +    Q
Sbjct: 68  -------------ELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQ 114

Query: 295 DVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTI 354
           + L  + E  +  N+   LI      +   +I+P LQ+R  C      F P T   +V  
Sbjct: 115 NALRRVIE-KFTENTRFCLI-----CNYLSKIIPALQSR--C--TRFRFGPLTPELMV-- 162

Query: 355 LQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDV 393
              RL  V  ++ +D +     A  V+  SGD+R+AL++
Sbjct: 163 --PRLEHVVEEEKVDISEDGMKA-LVTLSSGDMRRALNI 198


>gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]
          Length = 319

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 55/219 (25%), Positives = 91/219 (41%), Gaps = 44/219 (20%)

Query: 179 MDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRT 238
           +  I+ F+ E     +   L L G PGTGKT+ +    + L K+ K F +++L       
Sbjct: 20  LSTIQKFINED----RLPHLLLYGPPGTGKTSTILACAKQLYKD-KEFGSMVL------- 67

Query: 239 AQAVFPAIAQEICQEEVSRPAGKDMMR----KLEKHMTAEKGPMIVLVLDEMDQLDSKGQ 294
                        +   S   G D++R          T  K    +++LDE D +    Q
Sbjct: 68  -------------ELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQ 114

Query: 295 DVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTI 354
           + L  + E  +  N+   LI      +   +I+P LQ+R  C      F P T   +V  
Sbjct: 115 NALRRVIE-KFTENTRFCLI-----CNYLSKIIPALQSR--C--TRFRFGPLTPELMV-- 162

Query: 355 LQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDV 393
              RL  V  ++ +D +     A  V+  SGD+R+AL++
Sbjct: 163 --PRLEHVVEEEKVDISEDGMKA-LVTLSSGDMRRALNI 198


>gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]
          Length = 340

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 55/219 (25%), Positives = 91/219 (41%), Gaps = 44/219 (20%)

Query: 179 MDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRT 238
           +  I+ F+ E     +   L L G PGTGKT+ +    + L K+ K F +++L       
Sbjct: 41  LSTIQKFINED----RLPHLLLYGPPGTGKTSTILACAKQLYKD-KEFGSMVL------- 88

Query: 239 AQAVFPAIAQEICQEEVSRPAGKDMMR----KLEKHMTAEKGPMIVLVLDEMDQLDSKGQ 294
                        +   S   G D++R          T  K    +++LDE D +    Q
Sbjct: 89  -------------ELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQ 135

Query: 295 DVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTI 354
           + L  + E  +  N+   LI      +   +I+P LQ+R  C      F P T   +V  
Sbjct: 136 NALRRVIE-KFTENTRFCLI-----CNYLSKIIPALQSR--C--TRFRFGPLTPELMV-- 183

Query: 355 LQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDV 393
              RL  V  ++ +D +     A  V+  SGD+R+AL++
Sbjct: 184 --PRLEHVVEEEKVDISEDGMKA-LVTLSSGDMRRALNI 219


>gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]
          Length = 354

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 50/208 (24%), Positives = 89/208 (42%), Gaps = 56/208 (26%)

Query: 197 SLYLSGAPGTGKTA---CLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQE 253
           ++ ++G PGTGKT    CL+R L                         + PA+   + + 
Sbjct: 71  NIIIAGPPGTGKTTSILCLARAL-------------------------LGPALKDAMLEL 105

Query: 254 EVSRPAGKDMMRK-----LEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSN 308
             S   G D++R       ++ +T  KG   +++LDE D +    Q  L    E      
Sbjct: 106 NASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTME------ 159

Query: 309 SHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQV- 367
            +      A   + +D+I+  +Q+R  C   +L +   T  QI+T L   +N + +++V 
Sbjct: 160 IYSKTTRFALACNASDKIIEPIQSR--C--AVLRYTKLTDAQILTRL---MNVIEKERVP 212

Query: 368 -LDNA--AVQFCARKVSAVSGDVRKALD 392
             D+   A+ F A+      GD+R+AL+
Sbjct: 213 YTDDGLEAIIFTAQ------GDMRQALN 234


>gi|32454748 origin recognition complex subunit 4 [Homo sapiens]
          Length = 436

 Score = 36.6 bits (83), Expect = 0.063
 Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 29/177 (16%)

Query: 194 KAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQE 253
           ++ S+ + G  G+GKT  ++  L    KEL   + +  N + +     +   I  +I  +
Sbjct: 59  ESNSVLIIGPRGSGKTMLINHAL----KELMEIEEVSENVLQVHLNGLL--QINDKIALK 112

Query: 254 EVSRPAGKD-----------------MMRKLEKHMTAEKGPMIVLVLDEMDQL-DSKGQD 295
           E++R    +                 ++  L+K       P ++ +LDE D     K Q 
Sbjct: 113 EITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCP-VIFILDEFDLFAHHKNQT 171

Query: 296 VLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKP-QLLN---FPPYTR 348
           +LY LF+    + + + +IG+   LD+ + +  R+++R   +   L+N   FP Y +
Sbjct: 172 LLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVK 228


>gi|32454746 origin recognition complex subunit 4 [Homo sapiens]
          Length = 436

 Score = 36.6 bits (83), Expect = 0.063
 Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 29/177 (16%)

Query: 194 KAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQE 253
           ++ S+ + G  G+GKT  ++  L    KEL   + +  N + +     +   I  +I  +
Sbjct: 59  ESNSVLIIGPRGSGKTMLINHAL----KELMEIEEVSENVLQVHLNGLL--QINDKIALK 112

Query: 254 EVSRPAGKD-----------------MMRKLEKHMTAEKGPMIVLVLDEMDQL-DSKGQD 295
           E++R    +                 ++  L+K       P ++ +LDE D     K Q 
Sbjct: 113 EITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCP-VIFILDEFDLFAHHKNQT 171

Query: 296 VLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKP-QLLN---FPPYTR 348
           +LY LF+    + + + +IG+   LD+ + +  R+++R   +   L+N   FP Y +
Sbjct: 172 LLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVK 228


>gi|32454750 origin recognition complex subunit 4 [Homo sapiens]
          Length = 436

 Score = 36.6 bits (83), Expect = 0.063
 Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 29/177 (16%)

Query: 194 KAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQE 253
           ++ S+ + G  G+GKT  ++  L    KEL   + +  N + +     +   I  +I  +
Sbjct: 59  ESNSVLIIGPRGSGKTMLINHAL----KELMEIEEVSENVLQVHLNGLL--QINDKIALK 112

Query: 254 EVSRPAGKD-----------------MMRKLEKHMTAEKGPMIVLVLDEMDQL-DSKGQD 295
           E++R    +                 ++  L+K       P ++ +LDE D     K Q 
Sbjct: 113 EITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCP-VIFILDEFDLFAHHKNQT 171

Query: 296 VLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKP-QLLN---FPPYTR 348
           +LY LF+    + + + +IG+   LD+ + +  R+++R   +   L+N   FP Y +
Sbjct: 172 LLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVK 228


>gi|169234742 NACHT and WD repeat domain containing 1 [Homo sapiens]
          Length = 1429

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 67/303 (22%), Positives = 118/303 (38%), Gaps = 48/303 (15%)

Query: 189 HICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTI----MLNCMSLRT-AQAVF 243
           H   K+   L L G PG GKTA + ++ + + + L G KT+    +L    + + A+ + 
Sbjct: 193 HDDSKQHTPLVLFGPPGIGKTALMCKLAEQMPR-LLGHKTVTVLRLLGTSQMSSDARGLL 251

Query: 244 PAIAQEIC----------QEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKG 293
            +I  ++C          Q   +          L   ++      +VL+LD MD LDS  
Sbjct: 252 KSICFQVCLAYGLPLPPAQVLDAHTRVVQFFHTLLHTVSCRNFESLVLLLDAMDDLDS-- 309

Query: 294 QDVLYTLFEWPWL-----SNSHLVL---IGIANTLDLTDRILPRLQAREKCKPQLLNFPP 345
              +      PWL        HL+L    G    LD   R+L   +A  + KP   N   
Sbjct: 310 ---VRHARRVPWLPLNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQ 366

Query: 346 YTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDV 405
                ++   +  L+ V  D +   A++  C        G +R A +  R+         
Sbjct: 367 QMIQLLLAAARRTLSPVHTDLLW--ASLPECGN-----PGRLRLAFEEARK--------W 411

Query: 406 KSQTILKPLSECKSPSEPLIPKRV----GLIHISQVISEVDGNRMTLSQEGAQDSFPLQQ 461
            S T+  PL+     +   +  R+    G + ++ V+  +  +R  LS+   +D   L  
Sbjct: 412 ASFTVPVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDD 471

Query: 462 KIL 464
           ++L
Sbjct: 472 EVL 474


>gi|5453593 adenylyl cyclase-associated protein 2 [Homo sapiens]
          Length = 477

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 20/97 (20%)

Query: 68  PHLPPCSPP----KQGKKENGPPHSHTL-----------KGRRLVFDNQLTIKSPSKREL 112
           P LPP  PP     +GKKE   P    L           KG R V D+Q T K+PS R  
Sbjct: 236 PPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRA- 294

Query: 113 AKVHQNKILSSVRKSQEITTNSEQRCPLKKESACVRL 149
               Q     S  KS   +  S +  P +K +  + L
Sbjct: 295 ----QGGQTQSPTKSHTPSPTSPKSYPSQKHAPVLEL 327


>gi|32528306 replication factor C large subunit [Homo sapiens]
          Length = 1147

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 9/63 (14%)

Query: 192 GKKAGSLY----LSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIA 247
           GK  GS +    LSG PG GKT   S + Q+L     G+  + LN    R+  ++   +A
Sbjct: 636 GKDDGSSFKAALLSGPPGVGKTTTASLVCQEL-----GYSYVELNASDTRSKSSLKAIVA 690

Query: 248 QEI 250
           + +
Sbjct: 691 ESL 693


>gi|4758646 kinesin family member 3B [Homo sapiens]
          Length = 747

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 31/119 (26%), Positives = 48/119 (40%), Gaps = 3/119 (2%)

Query: 153 EGTCYQQAKLVLNTAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACL 212
           +GT ++  K     AV D    +    D     L + +     G+++  G  GTGKT  +
Sbjct: 47  KGTAHEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTM 106

Query: 213 SRILQDLKKE---LKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLE 268
             I  D +K       F  I  +    +  Q +  A   EI QEE+     KD  ++LE
Sbjct: 107 EGIRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLE 165


>gi|14043024 BCL2-associated athanogene 3 [Homo sapiens]
          Length = 575

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 18/62 (29%), Positives = 27/62 (43%)

Query: 31  DAKLEPTNVQTVTCSPRVKALPLSPRKRLGDDNLCNTPHLPPCSPPKQGKKENGPPHSHT 90
           + K+ P  V     SP   A+P SP+    ++    +      +PPK G+ E  P H   
Sbjct: 363 EVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPGV 422

Query: 91  LK 92
           LK
Sbjct: 423 LK 424


>gi|31881687 replication factor C 4 [Homo sapiens]
          Length = 363

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 52/218 (23%), Positives = 86/218 (39%), Gaps = 31/218 (14%)

Query: 186 LREHICGKKAGSLYLSGAPGTGKTACLSRILQDL-KKELKGFKTIMLNCMSLRTAQAVFP 244
           L++ + G    +L   G PGTGKT+ +    ++L   EL   + + LN    R  Q V  
Sbjct: 62  LKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVRE 121

Query: 245 AIAQEICQEEV--SRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFE 302
            + +   Q  V  SR  GK               P  +++LDE D + S  Q  L    E
Sbjct: 122 KV-KNFAQLTVSGSRSDGKPC------------PPFKIVILDEADSMTSAAQAALRRTME 168

Query: 303 WPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQV 362
               +    ++       +   RI+  L +R  C      F P +      I Q RL  +
Sbjct: 169 KESKTTRFCLI------CNYVSRIIEPLTSR--CSK--FRFKPLSDK----IQQQRLLDI 214

Query: 363 SRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEI 400
           ++ + +   + +  A  V    GD+RKA+   + A  +
Sbjct: 215 AKKENV-KISDEGIAYLVKVSEGDLRKAITFLQSATRL 251


>gi|4506491 replication factor C 4 [Homo sapiens]
          Length = 363

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 52/218 (23%), Positives = 86/218 (39%), Gaps = 31/218 (14%)

Query: 186 LREHICGKKAGSLYLSGAPGTGKTACLSRILQDL-KKELKGFKTIMLNCMSLRTAQAVFP 244
           L++ + G    +L   G PGTGKT+ +    ++L   EL   + + LN    R  Q V  
Sbjct: 62  LKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVRE 121

Query: 245 AIAQEICQEEV--SRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFE 302
            + +   Q  V  SR  GK               P  +++LDE D + S  Q  L    E
Sbjct: 122 KV-KNFAQLTVSGSRSDGKPC------------PPFKIVILDEADSMTSAAQAALRRTME 168

Query: 303 WPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQV 362
               +    ++       +   RI+  L +R  C      F P +      I Q RL  +
Sbjct: 169 KESKTTRFCLI------CNYVSRIIEPLTSR--CSK--FRFKPLSDK----IQQQRLLDI 214

Query: 363 SRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEI 400
           ++ + +   + +  A  V    GD+RKA+   + A  +
Sbjct: 215 AKKENV-KISDEGIAYLVKVSEGDLRKAITFLQSATRL 251


>gi|33667040 NLR family, pyrin domain containing 8 [Homo sapiens]
          Length = 1048

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 37/159 (23%), Positives = 71/159 (44%), Gaps = 22/159 (13%)

Query: 192 GKKAGSLYLSGAPGTGKTACLSRILQDLKKEL----KGFKTIMLNCMSL-RTAQAVFPAI 246
           G++  ++ + GAPG GKT    +++ +  +      K +     +C  + +T    F  +
Sbjct: 200 GRQPKTVAIQGAPGIGKTILAKKVMFEWARNKFYAHKRWCAFYFHCQEVNQTTDQSFSEL 259

Query: 247 AQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPW- 305
            ++        P  +D++ K+       K   ++L+LD  ++L S   D L  L E  W 
Sbjct: 260 IEQ------KWPGSQDLVSKI-----MSKPDQLLLLLDGFEELTSTLIDRLEDLSE-DWR 307

Query: 306 --LSNSHLVLIGIANTL--DLTDRILPRLQAREKCKPQL 340
             L  S L+   ++ T+  + T  I+ R  + + CKP L
Sbjct: 308 QKLPGSVLLSSLLSKTMLPEATLLIMIRFTSWQTCKPLL 346


>gi|75677353 AAA-ATPase  TOB3 [Homo sapiens]
          Length = 648

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 1/87 (1%)

Query: 68  PHLPPCSPPKQGKKENGPPHSHTLKGRRLVFD-NQLTIKSPSKRELAKVHQNKILSSVRK 126
           P LPP  P  +G  + G       K +   FD   L   + + REL      K   ++ +
Sbjct: 20  PPLPPAQPGAEGGGDRGLGDRPAPKDKWSNFDPTGLERAAKAARELEHSRYAKEALNLAQ 79

Query: 127 SQEITTNSEQRCPLKKESACVRLFKQE 153
            QE T   EQ+  LK+  A V   K E
Sbjct: 80  MQEQTLQLEQQSKLKEYEAAVEQLKSE 106


>gi|148664197 coiled-coil domain containing 40 [Homo sapiens]
          Length = 1142

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 48/182 (26%), Positives = 82/182 (45%), Gaps = 27/182 (14%)

Query: 380 VSAVSGDVRKA----------LDVCRRAIEIVESDVKSQTILKPLSECK-SPSEPLIPKR 428
           +S ++GD+ +           LD  ++ +  ++ DVK    L   S+ + S    LI ++
Sbjct: 667 LSKINGDIAQTTLDITHTSSRLDAHQKTLVELDQDVKKVNELITNSQSEISRRTILIERK 726

Query: 429 VGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEA 488
            GLI+      E    RM +S+ G ++  PL+ +I         R  K+ +   GK  +A
Sbjct: 727 QGLINFLNKQLE----RM-VSELGGEEVGPLELEIK--------RLSKLIDEHDGKAVQA 773

Query: 489 YSKVCRKQQ-VAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFF--KIEEKEIEHAL 545
                R QQ +  V Q +   L+ L  ++  L +   K+ R+       K E+KEIEH +
Sbjct: 774 QVTWLRLQQEMVKVTQEQEEQLASLDASKKELHIMEQKKLRVESKIEQEKKEQKEIEHHM 833

Query: 546 KD 547
           KD
Sbjct: 834 KD 835


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 36/170 (21%)

Query: 2    PQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEP---TNVQTVTCSPRVKALPLSPRKR 58
            PQ+  Q Q+    P R  S +  + + S+ ++L P   + VQT T  P    +P+ P   
Sbjct: 2331 PQSNVQGQS----PVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQP----IPIQPHTS 2382

Query: 59   LGDDNLCNTPHLPPCSPPKQGKKENGPP---HSHTLKGRRLVFDNQLTIKSPSKREL-AK 114
            L                P QG+ ++ P     + TL   + +  NQ+T+ SPS+ +L  +
Sbjct: 2383 L--------------QIPSQGQPQSQPQVQSSTQTLSSGQTL--NQVTVSSPSRPQLQIQ 2426

Query: 115  VHQNKILSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVL 164
              Q ++++  +  Q++   S+      +     ++  Q+    QQ KL L
Sbjct: 2427 QPQPQVIAVPQLQQQVQVLSQ-----IQSQVVAQIQAQQSGVPQQIKLQL 2471


>gi|167621456 kinase suppressor of ras 2 [Homo sapiens]
          Length = 921

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 34/126 (26%), Positives = 53/126 (42%), Gaps = 26/126 (20%)

Query: 49  KALPLSPRKRLGDDNLCNTPHL-----PPCSPPKQGKKENGPPHSHTLKGRRLV------ 97
           ++LP SPR+R        TP++     PP +PP + K +  PP +     R+L+      
Sbjct: 217 RSLPPSPRQRHAVRTPPRTPNIVTTVTPPGTPPMRKKNKLKPPGTPPPSSRKLIHLIPGF 276

Query: 98  --------FDNQL-----TIKSPSKRELAKVHQNKILSSVRKSQEITTNSEQRCPLKKES 144
                    + QL        +P  ++ +K    KI SSV   + I   S+QR PL  E 
Sbjct: 277 TALHRSKSHEFQLGHRVDEAHTPKAKKKSKPLNLKIHSSVGSCENIP--SQQRSPLLSER 334

Query: 145 ACVRLF 150
           +    F
Sbjct: 335 SLRSFF 340


>gi|19718796 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 64/301 (21%), Positives = 122/301 (40%), Gaps = 37/301 (12%)

Query: 122 SSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDR--------LP 173
           SS R+    +T    R P +K      L +  G    +  L  N    D+        L 
Sbjct: 34  SSHRRKNGPSTLESSRFPARKRGNLSSLEQIYGLENSKEYLSENEPWVDKYKPETQHELA 93

Query: 174 AREREMDVIRNFLREHICG---KKAGSLYL-SGAPGTGKTACLS--------RILQDLKK 221
             +++++ +  +L+  +     K+ GS+ L +G PG GKT  L         ++ + +  
Sbjct: 94  VHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEWINP 153

Query: 222 ELKGF-KTIMLNCMSLRTAQAVFPAIAQ-EICQEEVSRPAGKDMMRKLEKHMTAEKGPMI 279
            L  F K       +  ++  +FP  +Q  + +E + R    + ++ L   +  +K   I
Sbjct: 154 VLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDK--KI 211

Query: 280 VLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTL--DLTDRILPRLQAREKCK 337
           +LV D  +Q       +   L ++  +    L+ I I+++L  D   R+L   + +E+C 
Sbjct: 212 ILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFI-ISDSLSGDNNQRLLFPKEIQEECS 270

Query: 338 PQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVS------AVSGDVRKAL 391
              ++F P       TI+   LN++   +   N        K S        SGD+R A+
Sbjct: 271 ISNISFNPVA----PTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSGDIRSAI 326

Query: 392 D 392
           +
Sbjct: 327 N 327


>gi|19718794 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 64/301 (21%), Positives = 122/301 (40%), Gaps = 37/301 (12%)

Query: 122 SSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDR--------LP 173
           SS R+    +T    R P +K      L +  G    +  L  N    D+        L 
Sbjct: 34  SSHRRKNGPSTLESSRFPARKRGNLSSLEQIYGLENSKEYLSENEPWVDKYKPETQHELA 93

Query: 174 AREREMDVIRNFLREHICG---KKAGSLYL-SGAPGTGKTACLS--------RILQDLKK 221
             +++++ +  +L+  +     K+ GS+ L +G PG GKT  L         ++ + +  
Sbjct: 94  VHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEWINP 153

Query: 222 ELKGF-KTIMLNCMSLRTAQAVFPAIAQ-EICQEEVSRPAGKDMMRKLEKHMTAEKGPMI 279
            L  F K       +  ++  +FP  +Q  + +E + R    + ++ L   +  +K   I
Sbjct: 154 VLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDK--KI 211

Query: 280 VLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTL--DLTDRILPRLQAREKCK 337
           +LV D  +Q       +   L ++  +    L+ I I+++L  D   R+L   + +E+C 
Sbjct: 212 ILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFI-ISDSLSGDNNQRLLFPKEIQEECS 270

Query: 338 PQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVS------AVSGDVRKAL 391
              ++F P       TI+   LN++   +   N        K S        SGD+R A+
Sbjct: 271 ISNISFNPVA----PTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSGDIRSAI 326

Query: 392 D 392
           +
Sbjct: 327 N 327


>gi|19718792 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 64/301 (21%), Positives = 122/301 (40%), Gaps = 37/301 (12%)

Query: 122 SSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDR--------LP 173
           SS R+    +T    R P +K      L +  G    +  L  N    D+        L 
Sbjct: 34  SSHRRKNGPSTLESSRFPARKRGNLSSLEQIYGLENSKEYLSENEPWVDKYKPETQHELA 93

Query: 174 AREREMDVIRNFLREHICG---KKAGSLYL-SGAPGTGKTACLS--------RILQDLKK 221
             +++++ +  +L+  +     K+ GS+ L +G PG GKT  L         ++ + +  
Sbjct: 94  VHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEWINP 153

Query: 222 ELKGF-KTIMLNCMSLRTAQAVFPAIAQ-EICQEEVSRPAGKDMMRKLEKHMTAEKGPMI 279
            L  F K       +  ++  +FP  +Q  + +E + R    + ++ L   +  +K   I
Sbjct: 154 VLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDK--KI 211

Query: 280 VLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTL--DLTDRILPRLQAREKCK 337
           +LV D  +Q       +   L ++  +    L+ I I+++L  D   R+L   + +E+C 
Sbjct: 212 ILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFI-ISDSLSGDNNQRLLFPKEIQEECS 270

Query: 338 PQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVS------AVSGDVRKAL 391
              ++F P       TI+   LN++   +   N        K S        SGD+R A+
Sbjct: 271 ISNISFNPVA----PTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSGDIRSAI 326

Query: 392 D 392
           +
Sbjct: 327 N 327


>gi|19718784 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 64/301 (21%), Positives = 122/301 (40%), Gaps = 37/301 (12%)

Query: 122 SSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDR--------LP 173
           SS R+    +T    R P +K      L +  G    +  L  N    D+        L 
Sbjct: 34  SSHRRKNGPSTLESSRFPARKRGNLSSLEQIYGLENSKEYLSENEPWVDKYKPETQHELA 93

Query: 174 AREREMDVIRNFLREHICG---KKAGSLYL-SGAPGTGKTACLS--------RILQDLKK 221
             +++++ +  +L+  +     K+ GS+ L +G PG GKT  L         ++ + +  
Sbjct: 94  VHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEWINP 153

Query: 222 ELKGF-KTIMLNCMSLRTAQAVFPAIAQ-EICQEEVSRPAGKDMMRKLEKHMTAEKGPMI 279
            L  F K       +  ++  +FP  +Q  + +E + R    + ++ L   +  +K   I
Sbjct: 154 VLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDK--KI 211

Query: 280 VLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTL--DLTDRILPRLQAREKCK 337
           +LV D  +Q       +   L ++  +    L+ I I+++L  D   R+L   + +E+C 
Sbjct: 212 ILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFI-ISDSLSGDNNQRLLFPKEIQEECS 270

Query: 338 PQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVS------AVSGDVRKAL 391
              ++F P       TI+   LN++   +   N        K S        SGD+R A+
Sbjct: 271 ISNISFNPVA----PTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSGDIRSAI 326

Query: 392 D 392
           +
Sbjct: 327 N 327


>gi|4506383 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 64/301 (21%), Positives = 122/301 (40%), Gaps = 37/301 (12%)

Query: 122 SSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDR--------LP 173
           SS R+    +T    R P +K      L +  G    +  L  N    D+        L 
Sbjct: 34  SSHRRKNGPSTLESSRFPARKRGNLSSLEQIYGLENSKEYLSENEPWVDKYKPETQHELA 93

Query: 174 AREREMDVIRNFLREHICG---KKAGSLYL-SGAPGTGKTACLS--------RILQDLKK 221
             +++++ +  +L+  +     K+ GS+ L +G PG GKT  L         ++ + +  
Sbjct: 94  VHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEWINP 153

Query: 222 ELKGF-KTIMLNCMSLRTAQAVFPAIAQ-EICQEEVSRPAGKDMMRKLEKHMTAEKGPMI 279
            L  F K       +  ++  +FP  +Q  + +E + R    + ++ L   +  +K   I
Sbjct: 154 VLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDK--KI 211

Query: 280 VLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTL--DLTDRILPRLQAREKCK 337
           +LV D  +Q       +   L ++  +    L+ I I+++L  D   R+L   + +E+C 
Sbjct: 212 ILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFI-ISDSLSGDNNQRLLFPKEIQEECS 270

Query: 338 PQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVS------AVSGDVRKAL 391
              ++F P       TI+   LN++   +   N        K S        SGD+R A+
Sbjct: 271 ISNISFNPVA----PTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSGDIRSAI 326

Query: 392 D 392
           +
Sbjct: 327 N 327


>gi|19718786 RAD17 homolog isoform 2 [Homo sapiens]
          Length = 681

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 64/301 (21%), Positives = 122/301 (40%), Gaps = 37/301 (12%)

Query: 122 SSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDR--------LP 173
           SS R+    +T    R P +K      L +  G    +  L  N    D+        L 
Sbjct: 45  SSHRRKNGPSTLESSRFPARKRGNLSSLEQIYGLENSKEYLSENEPWVDKYKPETQHELA 104

Query: 174 AREREMDVIRNFLREHICG---KKAGSLYL-SGAPGTGKTACLS--------RILQDLKK 221
             +++++ +  +L+  +     K+ GS+ L +G PG GKT  L         ++ + +  
Sbjct: 105 VHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEWINP 164

Query: 222 ELKGF-KTIMLNCMSLRTAQAVFPAIAQ-EICQEEVSRPAGKDMMRKLEKHMTAEKGPMI 279
            L  F K       +  ++  +FP  +Q  + +E + R    + ++ L   +  +K   I
Sbjct: 165 VLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDK--KI 222

Query: 280 VLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTL--DLTDRILPRLQAREKCK 337
           +LV D  +Q       +   L ++  +    L+ I I+++L  D   R+L   + +E+C 
Sbjct: 223 ILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFI-ISDSLSGDNNQRLLFPKEIQEECS 281

Query: 338 PQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVS------AVSGDVRKAL 391
              ++F P       TI+   LN++   +   N        K S        SGD+R A+
Sbjct: 282 ISNISFNPVA----PTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSGDIRSAI 337

Query: 392 D 392
           +
Sbjct: 338 N 338


>gi|157057547 Fc receptor-like 6 [Homo sapiens]
          Length = 434

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 38/150 (25%), Positives = 66/150 (44%), Gaps = 23/150 (15%)

Query: 285 EMDQLDSKGQDVLYT-LFEW--PWLSNSHLVLIGIANTL-----------DLTDRILPRL 330
           E  +L  KG  VL+T    W  PWL  S L L+ IA  L            L  +I P  
Sbjct: 288 EPKKLSLKGSQVLFTPASNWLVPWLPASLLGLMVIAAALLVYVRSWRKAGPLPSQIPPTA 347

Query: 331 QAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKA 390
              E+C P   N   + + +   ++   +++ S+     +A      +  S +  +VR  
Sbjct: 348 PGGEQC-PLYANVH-HQKGKDEGVVYSVVHRTSKRSEARSAEFTVGRKDSSIICAEVR-- 403

Query: 391 LDVCRRAIEIVESDV--KSQTILKPLSECK 418
              C +  E+  ++V  +S+T+ +PLS+C+
Sbjct: 404 ---CLQPSEVSSTEVNMRSRTLQEPLSDCE 430


>gi|223555989 hypothetical protein LOC51101 [Homo sapiens]
          Length = 325

 Score = 30.8 bits (68), Expect = 3.4
 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 9/109 (8%)

Query: 8   AQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLGDDNLCNT 67
           A   I+F K + +R  NK K S+D K +PT+   V   P +K          G   L   
Sbjct: 134 ADRHINFCKEQAARISNKGKFSTDTKGKPTSRTQVYKPPALKKSNSPGTASSGSSRL--- 190

Query: 68  PHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVH 116
                  P   GK   G P S  +        N+L   SPS + +A  H
Sbjct: 191 -----PQPSGAGKTVVGVP-SGKVSSSSSSLGNKLQTLSPSHKGIAAPH 233


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,954,585
Number of Sequences: 37866
Number of extensions: 940642
Number of successful extensions: 3126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 3112
Number of HSP's gapped (non-prelim): 51
length of query: 560
length of database: 18,247,518
effective HSP length: 107
effective length of query: 453
effective length of database: 14,195,856
effective search space: 6430722768
effective search space used: 6430722768
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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