Search of human proteins with 4502333

Search of human proteins with 4502333

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]
         (424 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]            867   0.0  
gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]            367   e-101
gi|32307152 oxytocin receptor [Homo sapiens]                          360   1e-99
gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]   269   4e-72
gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo sap...   236   4e-62
gi|46395496 G protein-coupled receptor for asthma susceptibility...   155   7e-38
gi|46391085 G protein-coupled receptor for asthma susceptibility...   155   7e-38
gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Ho...   119   4e-27
gi|28875799 cholecystokinin B receptor [Homo sapiens]                 117   2e-26
gi|4502607 cholecystokinin A receptor [Homo sapiens]                  115   6e-26
gi|157738685 G protein-coupled receptor 103 [Homo sapiens]            106   5e-23
gi|4557865 somatostatin receptor 5 [Homo sapiens]                     100   4e-21
gi|149944554 somatostatin receptor 4 [Homo sapiens]                    97   4e-20
gi|222080109 orexin receptor 2 [Homo sapiens]                          96   6e-20
gi|4557857 somatostatin receptor 1 [Homo sapiens]                      96   8e-20
gi|5453666 G protein-coupled receptor 19 [Homo sapiens]                96   8e-20
gi|21426829 prokineticin receptor 2 [Homo sapiens]                     95   1e-19
gi|20373179 G protein-coupled receptor 73 [Homo sapiens]               92   7e-19
gi|222080095 orexin receptor 1 [Homo sapiens]                          92   1e-18
gi|4503907 galanin receptor 3 [Homo sapiens]                           91   2e-18
gi|4505513 opiate receptor-like 1 [Homo sapiens]                       91   2e-18
gi|33286424 opiate receptor-like 1 [Homo sapiens]                      91   2e-18
gi|62865887 G protein-coupled receptor 54 [Homo sapiens]               90   4e-18
gi|9506745 urotensin 2 receptor [Homo sapiens]                         90   4e-18
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]       89   8e-18
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]        89   8e-18
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]      89   8e-18
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]      89   8e-18
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]      89   8e-18
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]      89   8e-18

>gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]
          Length = 424

 Score =  867 bits (2240), Expect = 0.0
 Identities = 424/424 (100%), Positives = 424/424 (100%)

Query: 1   MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG 60
           MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG
Sbjct: 1   MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG 60

Query: 61  QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA 120
           QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA
Sbjct: 61  QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA 120

Query: 121 STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG 180
           STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG
Sbjct: 121 STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG 180

Query: 181 SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG 240
           SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG
Sbjct: 181 SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG 240

Query: 241 GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV 300
           GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
Sbjct: 241 GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV 300

Query: 301 QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ 360
           QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ
Sbjct: 301 QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ 360

Query: 361 PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE 420
           PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE
Sbjct: 361 PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE 420

Query: 421 TIIF 424
           TIIF
Sbjct: 421 TIIF 424


>gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]
          Length = 418

 Score =  367 bits (942), Expect = e-101
 Identities = 190/351 (54%), Positives = 237/351 (67%), Gaps = 12/351 (3%)

Query: 29  RDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQV 88
           R+EELAK+EI VLA    +A  GN +VLL L +  RK SRMHLF+ HL+L DLAVA FQV
Sbjct: 46  RNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQV 105

Query: 89  LPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQ 148
           LPQ+ WDITYRF+GPD LCR VK+LQV  MFAS YML+ MT DRY+AVCHPL++LQQP +
Sbjct: 106 LPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPAR 165

Query: 149 STYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIF 208
            + L+IAA W+L+ + S PQ F+FS+ EV   +   DCWA F  PWG RAY+TW T  IF
Sbjct: 166 RSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIF 225

Query: 209 VLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRG--LPSRV 266
           V PV +L  CY  IC+ I  N++ KT + +  G         +     A  +G  L   V
Sbjct: 226 VAPVVILGTCYGFICYNIWCNVRGKTASRQSKG---------AEQAGVAFQKGFLLAPCV 276

Query: 267 SSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLL 326
           SS+ +ISRAKIRTVKMTFVIV AYI CWAPFF +QMWSVWD  +   +S N   TI+ LL
Sbjct: 277 SSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALL 336

Query: 327 GNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHT 377
           G+LNSCCNPWIYM F+ HLL   ++   CC   + +  +  +D S+S R T
Sbjct: 337 GSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTD-SMSRRQT 386


>gi|32307152 oxytocin receptor [Homo sapiens]
          Length = 389

 Score =  360 bits (924), Expect = 1e-99
 Identities = 194/368 (52%), Positives = 242/368 (65%), Gaps = 17/368 (4%)

Query: 8   DANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRS 67
           +A+  P G      A  P   R+E LA+VE+ VL  +L+LA  GN  VLL L    +K S
Sbjct: 15  NASAAPPGAEGNRTAGPP--RRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHS 72

Query: 68  RMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLA 127
           R+  F+ HL++ DL VA+FQVLPQLLWDIT+RF GPDLLCR VKYLQV+ MFASTY+LL 
Sbjct: 73  RLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLL 132

Query: 128 MTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCW 187
           M+LDR LA+C PLRSL++  ++  L + A WL   + S PQV IFSLREV    GV DCW
Sbjct: 133 MSLDRCLAICQPLRSLRR--RTDRLAVLATWLGCLVASAPQVHIFSLREV--ADGVFDCW 188

Query: 188 ADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTW 247
           A F  PWGP+AY+TW TLA++++PV +L ACY LI  +I +NL++KT A           
Sbjct: 189 AVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAA------- 241

Query: 248 DRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWD 307
           + P  +      R   +RVSS+  IS+AKIRTVKMTF+IVLA+I CW PFF VQMWSVWD
Sbjct: 242 EAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD 301

Query: 308 KNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRL 367
            NAP E S   AF I MLL +LNSCCNPWIYM F  HL    ++   CC     +  RRL
Sbjct: 302 ANAPKEAS---AFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLK-GRRL 357

Query: 368 SDGSLSSR 375
            + S S +
Sbjct: 358 GETSASKK 365


>gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]
          Length = 371

 Score =  269 bits (687), Expect = 4e-72
 Identities = 154/333 (46%), Positives = 198/333 (59%), Gaps = 27/333 (8%)

Query: 29  RDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKR--SRMHLFVLHLALTDLAVALF 86
           RD  LA+ E+ +L+ V V     N  VL  L + GR+   + +H+F+ HL L DLAVALF
Sbjct: 32  RDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALF 91

Query: 87  QVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQ- 145
           QVLPQL W  T RF+GPD LCRAVKYLQ++ M+AS+YM+LAMTLDR+ A+C P+ + +  
Sbjct: 92  QVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHG 151

Query: 146 PGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTL 205
            G      +   W  + + SLPQ+FIF+ R V  GSGV DCWA F  PWG R Y+TW  L
Sbjct: 152 SGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIAL 211

Query: 206 AIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGG--GWRTWDRPSPSTLAATTRGLP 263
            +FV P   + AC  LI  EI  +L V   + R GG   G RT              G P
Sbjct: 212 MVFVAPTLGIAACQVLIFREIHASL-VPGPSERPGGRRRGRRT--------------GSP 256

Query: 264 SRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTIS 323
              + +   S A  +TV+MT VIV+ Y+ CWAPFF VQ+W+ WD  AP E +    F + 
Sbjct: 257 GEGAHV---SAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAP---FVLL 310

Query: 324 MLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACC 356
           MLL +LNSC NPWIY  F+S  +   LR L CC
Sbjct: 311 MLLASLNSCTNPWIYASFSSS-VSSELRSLLCC 342


>gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo
           sapiens]
          Length = 309

 Score =  236 bits (601), Expect = 4e-62
 Identities = 134/290 (46%), Positives = 173/290 (59%), Gaps = 23/290 (7%)

Query: 29  RDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKR--SRMHLFVLHLALTDLAVALF 86
           RD  LA+ E+ +L+ V V     N  VL  L + GR+   + +H+F+ HL L DLAVALF
Sbjct: 32  RDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALF 91

Query: 87  QVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQ- 145
           QVLPQL W  T RF+GPD LCRAVKYLQ++ M+AS+YM+LAMTLDR+ A+C P+ + +  
Sbjct: 92  QVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHG 151

Query: 146 PGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTL 205
            G      +   W  + + SLPQ+FIF+ R V  GSGV DCWA F  PWG R Y+TW  L
Sbjct: 152 SGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIAL 211

Query: 206 AIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGG--GGWRTWDRPSPSTLAATTRGLP 263
            +FV P   + AC  LI  EI  +L V   + R GG   G RT              G P
Sbjct: 212 MVFVAPTLGIAACQVLIFREIHASL-VPGPSERPGGRRRGRRT--------------GSP 256

Query: 264 SRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDE 313
              +    +S A  +TV+MT VIV+ Y+ CWAPFF VQ+W+ WD  AP E
Sbjct: 257 GEGAH---VSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLE 303


>gi|46395496 G protein-coupled receptor for asthma susceptibility
           isoform A [Homo sapiens]
          Length = 371

 Score =  155 bits (392), Expect = 7e-38
 Identities = 101/308 (32%), Positives = 164/308 (53%), Gaps = 29/308 (9%)

Query: 41  LATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRF 100
           L  + V    GN  VL +  +  +K+SRM  FV  LA+TD    L  +L  + W  T  F
Sbjct: 56  LWVLFVFTIVGNSVVLFSTWRR-KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDF 114

Query: 101 QGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLL 160
             PDL+CR V+YLQV+ ++ASTY+L+++++DRY A+ +P++ LQ   Q+  L++ A W L
Sbjct: 115 TAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIA-WSL 173

Query: 161 AAIFSLPQVFIFSLREVIQGSGVLDCWA---DFGFPWGPRAYLTWTTLAIFVLPVTMLTA 217
           + +FS+P + IF  R +   +G + CWA   D  + W P  Y+T     ++ +P+T+++ 
Sbjct: 174 SFLFSIPTLIIFGKRTL--SNGEVQCWALWPDDSY-WTP--YMTIVAFLVYFIPLTIISI 228

Query: 218 CYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKI 277
            Y ++   I   +K KT    +        +       ++  RGL         IS+AKI
Sbjct: 229 MYGIVIRTIW--IKSKTYETVIS-------NCSDGKLCSSYNRGL---------ISKAKI 270

Query: 278 RTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWI 337
           + +K + +I+LA+I CW+P+F   +   ++   PD      A  I   L  LNS  NP I
Sbjct: 271 KAIKYSIIIILAFICCWSPYFLFDILDNFNL-LPDTQERFYASVIIQNLPALNSAINPLI 329

Query: 338 YMGFNSHL 345
           Y  F+S +
Sbjct: 330 YCVFSSSI 337


>gi|46391085 G protein-coupled receptor for asthma susceptibility
           isoform B [Homo sapiens]
          Length = 377

 Score =  155 bits (392), Expect = 7e-38
 Identities = 101/308 (32%), Positives = 164/308 (53%), Gaps = 29/308 (9%)

Query: 41  LATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRF 100
           L  + V    GN  VL +  +  +K+SRM  FV  LA+TD    L  +L  + W  T  F
Sbjct: 56  LWVLFVFTIVGNSVVLFSTWRR-KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDF 114

Query: 101 QGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLL 160
             PDL+CR V+YLQV+ ++ASTY+L+++++DRY A+ +P++ LQ   Q+  L++ A W L
Sbjct: 115 TAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIA-WSL 173

Query: 161 AAIFSLPQVFIFSLREVIQGSGVLDCWA---DFGFPWGPRAYLTWTTLAIFVLPVTMLTA 217
           + +FS+P + IF  R +   +G + CWA   D  + W P  Y+T     ++ +P+T+++ 
Sbjct: 174 SFLFSIPTLIIFGKRTL--SNGEVQCWALWPDDSY-WTP--YMTIVAFLVYFIPLTIISI 228

Query: 218 CYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKI 277
            Y ++   I   +K KT    +        +       ++  RGL         IS+AKI
Sbjct: 229 MYGIVIRTIW--IKSKTYETVIS-------NCSDGKLCSSYNRGL---------ISKAKI 270

Query: 278 RTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWI 337
           + +K + +I+LA+I CW+P+F   +   ++   PD      A  I   L  LNS  NP I
Sbjct: 271 KAIKYSIIIILAFICCWSPYFLFDILDNFNL-LPDTQERFYASVIIQNLPALNSAINPLI 329

Query: 338 YMGFNSHL 345
           Y  F+S +
Sbjct: 330 YCVFSSSI 337


>gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Homo
           sapiens]
          Length = 328

 Score =  119 bits (299), Expect = 4e-27
 Identities = 86/324 (26%), Positives = 152/324 (46%), Gaps = 48/324 (14%)

Query: 35  KVEIGVLATVLVLATGGNLAVLLTLG------QLGRKRSRMHLFVLHLALTDLAVALFQV 88
           K+ + V   + +L+   N + LL L       + G+K SRM L + HL L +L   L  +
Sbjct: 36  KIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVM 95

Query: 89  LPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHP--LRSLQQP 146
               +W+IT ++   +LLC+ + YL++ SM+A  +M++ ++LDR LA+  P  L+S  + 
Sbjct: 96  PLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKV 155

Query: 147 GQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWA------DFGFPWGPRAYL 200
           GQS   ++   W+L+++F+ PQ++IF +  +   SG    ++       F   W    Y 
Sbjct: 156 GQS---MVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYN 212

Query: 201 TWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTR 260
            +T   +F++P+ ++  C + I   + + L                     P  L     
Sbjct: 213 FFTFSCLFIIPLFIMLICNAKIIFTLTRVL------------------HQDPHELQLN-- 252

Query: 261 GLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPD--EDSTNV 318
                  S N I RA+++T+KMT     ++  CW P++ + +W  +D    +   D  N 
Sbjct: 253 ------QSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNH 306

Query: 319 AFTISMLLGNLNSCCNPWIYMGFN 342
            F    L   LN C +P IY  F+
Sbjct: 307 FF---FLFAFLNPCFDPLIYGYFS 327


>gi|28875799 cholecystokinin B receptor [Homo sapiens]
          Length = 447

 Score =  117 bits (294), Expect = 2e-26
 Identities = 104/384 (27%), Positives = 164/384 (42%), Gaps = 61/384 (15%)

Query: 29  RDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVAL--- 85
           R+ ELA + I + A + +++ GGN+ +++ LG   R R+  + F+L LA++DL +A+   
Sbjct: 50  RELELA-IRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACM 108

Query: 86  -FQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRS-L 143
            F +LP L+    +      ++C+AV YL  +S+  ST  L+A+ L+RY A+C PL++ +
Sbjct: 109 PFTLLPNLMGTFIFG----TVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARV 164

Query: 144 QQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQ--GSGVLDC---WADFGFPWGPRA 198
            Q       +I A WLL+ +  +P    + +  V+Q  G  VL C   W         R 
Sbjct: 165 WQTRSHAARVIVATWLLSGLLMVP----YPVYTVVQPVGPRVLQCVHRWP------SARV 214

Query: 199 YLTWTT---LAIFVLPVTMLTACYSLICHEICKNL------------KVKTQAWRVG--- 240
             TW+    L +F +P  ++   Y LI  E+   L            +V+ Q    G   
Sbjct: 215 RQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVH 274

Query: 241 -GGGWR-----------------TWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKM 282
             G  R                    RP+    A T  G  S          AK R V+M
Sbjct: 275 QNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRM 334

Query: 283 TFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFN 342
             VIV+ +  CW P +S   W  +D        +    +   LL   ++C NP +Y   +
Sbjct: 335 LLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMH 394

Query: 343 SHLLPRPLRHLACCGGPQPRMRRR 366
                  L   A C    PR R R
Sbjct: 395 RRFRQACLETCARCCPRPPRARPR 418


>gi|4502607 cholecystokinin A receptor [Homo sapiens]
          Length = 428

 Score =  115 bits (289), Expect = 6e-26
 Identities = 99/386 (25%), Positives = 165/386 (42%), Gaps = 37/386 (9%)

Query: 9   ANPTPRGTLSAPNATTPWLGRD----EELAKVEIGVLATVLVLATGGNLAVLLTLGQLGR 64
           +N TP   L   N T   L +     E    V+I + + + +L+  GN  V+  L +  R
Sbjct: 12  SNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKR 71

Query: 65  KRSRMHLFVLHLALTDLAVALF----QVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA 120
            R+  ++F+L LA++DL + LF     ++P LL D  +       +C+   Y    S+  
Sbjct: 72  MRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFG----SAVCKTTTYFMGTSVSV 127

Query: 121 STYMLLAMTLDRYLAVCHPLRS-LQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQ 179
           ST+ L+A++L+RY A+C PL+S + Q       +IAA W L+     P     +L    +
Sbjct: 128 STFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTK 187

Query: 180 GSGVLDCWADFGFPWG--PRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAW 237
            +        F  P     +++ T+  L +F++P  ++   Y LI  E+ + +K +    
Sbjct: 188 NNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFEASQK 247

Query: 238 R---------VGGGGWRTWD--------RPSPSTLAATTRGLPSRVSSINTIS-----RA 275
           +            G +   D         P    L   + G  SR + I + S      A
Sbjct: 248 KSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNSSAANLMA 307

Query: 276 KIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNP 335
           K R ++M  VIV+ +  CW P FS   W  +D  + +   +    +  +LL   +SC NP
Sbjct: 308 KKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSYTSSCVNP 367

Query: 336 WIYMGFNSHLLPRPLRHLACCGGPQP 361
            IY   N       +    CC  P P
Sbjct: 368 IIYCFMNKRFRLGFMATFPCCPNPGP 393


>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
          Length = 431

 Score =  106 bits (264), Expect = 5e-23
 Identities = 87/344 (25%), Positives = 154/344 (44%), Gaps = 33/344 (9%)

Query: 20  PNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALT 79
           P   TP L    +LA V  GVL  +  LA  GN  V   + +    R+  ++F+  LAL+
Sbjct: 33  PLVYTPELPGRAKLALVLTGVL--IFALALFGNALVFYVVTRSKAMRTVTNIFICSLALS 90

Query: 80  DLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHP 139
           DL +  F +   +L +I+  + G   +C+ V ++Q  ++      +  + ++R+  + HP
Sbjct: 91  DLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHP 150

Query: 140 LR-SLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLR---EVIQGSGVLDCWADFGFPWG 195
            +   Q   +  + ++   WL+A I   P   +  L    + +     + C  ++  P  
Sbjct: 151 FKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVH 210

Query: 196 PRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTL 255
            + Y T+  + +F+LP+ ++   YS I +E    L +K    RVG G           ++
Sbjct: 211 QKIYTTFILVILFLLPLMVMLILYSKIGYE----LWIKK---RVGDG-----------SV 252

Query: 256 AATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQM---WSVWDKNAPD 312
             T  G       ++ I+R K R V M   +V  +  CWAPF  V M   +S ++K   D
Sbjct: 253 LRTIHG-----KEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEY-D 306

Query: 313 EDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACC 356
           + +  + F I  ++G  NS CNP +Y   N +     L  +  C
Sbjct: 307 DVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYC 350


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 94/357 (26%), Positives = 158/357 (44%), Gaps = 48/357 (13%)

Query: 3   SGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLA-TGGNLAVLLTLGQ 61
           S P W+A+     +    N T            V + VL  ++  A  GGN  V+  + +
Sbjct: 8   STPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLR 67

Query: 62  LGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQ--GPDLLCRAVKYLQVLSMF 119
             + ++  ++++L+LA+ D+   L   LP L       F   GP +LCR V  L  ++ F
Sbjct: 68  FAKMKTVTNIYILNLAVADVLYMLG--LPFLATQNAASFWPFGP-VLCRLVMTLDGVNQF 124

Query: 120 ASTYMLLAMTLDRYLAVCHPLRSLQ-QPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVI 178
            S + L  M++DRYLAV HPL S + +  +   L  AA W+L+   SLP + +F+  +V 
Sbjct: 125 TSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLP-LLVFA--DVQ 181

Query: 179 QGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWR 238
           +G      W +    WG   ++ +T +  F  P+ ++  CY LI       +KV+    R
Sbjct: 182 EGGTCNASWPEPVGLWGA-VFIIYTAVLGFFAPLLVICLCYLLIV------VKVRAAGVR 234

Query: 239 VGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFF 298
           VG                                 R++ +  +M  V+VL +  CW PFF
Sbjct: 235 VGC-----------------------------VRRRSERKVTRMVLVVVLVFAGCWLPFF 265

Query: 299 SVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLAC 355
           +V + ++     P E ++   +   ++L   NSC NP +Y GF S    +  + + C
Sbjct: 266 TVNIVNL-AVALPQEPASAGLYFFVVILSYANSCANPVLY-GFLSDNFRQSFQKVLC 320


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 81/319 (25%), Positives = 145/319 (45%), Gaps = 47/319 (14%)

Query: 40  VLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYR 99
           + A V ++   GN  V+  + +  + ++  ++++L+LA+ D    LF +    +      
Sbjct: 53  IYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVAD---ELFMLSVPFVASSAAL 109

Query: 100 FQGP--DLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLI-AA 156
              P   +LCRAV  +  L+MF S + L  +++DRY+AV HPLR+      S   LI   
Sbjct: 110 RHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLG 169

Query: 157 PWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLT 216
            WL + + +LP + IF+     +G   + C   +  P     ++ +T L  F+LPV  + 
Sbjct: 170 VWLASLLVTLP-IAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIG 228

Query: 217 ACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAK 276
            CY LI        K++  A R G      W +                        R++
Sbjct: 229 LCYLLIVG------KMRAVALRAG------WQQR----------------------RRSE 254

Query: 277 IRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPW 336
            +  ++  ++V+ ++ CW PF+ VQ+ +++       D+T     +S++L   NSC NP 
Sbjct: 255 KKITRLVLMVVVVFVLCWMPFYVVQLLNLF---VTSLDAT--VNHVSLILSYANSCANPI 309

Query: 337 IYMGFNSHLLPRPLRHLAC 355
           +Y GF S    R  + + C
Sbjct: 310 LY-GFLSDNFRRFFQRVLC 327


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 88/354 (24%), Positives = 150/354 (42%), Gaps = 25/354 (7%)

Query: 44  VLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGP 103
           V V+A  GN+ V + + +    R+  + F+++L+L D+ V +  +   L+ DIT  +   
Sbjct: 64  VFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFG 123

Query: 104 DLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPL--RSLQQPGQSTYLLIAAPWLLA 161
             LC+ + YLQ +S+  S   L  + LDR+ A+CHPL  +S  +  +++ ++I   W+++
Sbjct: 124 QSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVII---WIVS 180

Query: 162 AIFSLPQVFIFSLREVIQGSG-----VLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLT 216
            I  +PQ  +     V  G          C   +G    P+ Y     L  ++ P+ ++ 
Sbjct: 181 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV 240

Query: 217 ACY-----SLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINT 271
             Y      L C +I     V  + W+             P      T+   S V++   
Sbjct: 241 LAYLQIFRKLWCRQIPGTSSVVQRKWK------PLQPVSQPRGPGQPTKSRMSAVAAEIK 294

Query: 272 ISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWS-VWDKNAPDEDSTNVA--FTISMLLGN 328
             RA+ +T +M  +++L +  C+ P   + +   V+   A  ED   V   FT S  L  
Sbjct: 295 QIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVY 354

Query: 329 LNSCCNPWIYMGFNSHLLPR-PLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLT 381
            NS  NP IY   +             CC G   R   RL+ G  S+     LT
Sbjct: 355 ANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLT 408


>gi|4557857 somatostatin receptor 1 [Homo sapiens]
          Length = 391

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 83/322 (25%), Positives = 151/322 (46%), Gaps = 52/322 (16%)

Query: 40  VLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYR 99
           + + V ++   GN  V+  + +  + ++  ++++L+LA+ D  + L   +P L+     R
Sbjct: 64  IYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLS--VPFLVTSTLLR 121

Query: 100 -FQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLI-AAP 157
            +    LLCR V  +  ++MF S Y L  +++DRY+AV HP+++ +    +   ++    
Sbjct: 122 HWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGV 181

Query: 158 WLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLT----WTTLAIFVLPVT 213
           W+L+ +  LP + +FS R      G + C  +   P   + +L     +T L  F+LPV 
Sbjct: 182 WVLSLLVILP-IVVFS-RTAANSDGTVAC--NMLMPEPAQRWLVGFVLYTFLMGFLLPVG 237

Query: 214 MLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTIS 273
            +  CY LI   I K   V  +A      GW+                            
Sbjct: 238 AICLCYVLI---IAKMRMVALKA------GWQ-------------------------QRK 263

Query: 274 RAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCC 333
           R++ +   M  ++V+ ++ CW PF+ VQ+ +V+   A  +D+T     +S++LG  NSC 
Sbjct: 264 RSERKITLMVMMVVMVFVICWMPFYVVQLVNVF---AEQDDAT--VSQLSVILGYANSCA 318

Query: 334 NPWIYMGFNSHLLPRPLRHLAC 355
           NP +Y GF S    R  + + C
Sbjct: 319 NPILY-GFLSDNFKRSFQRILC 339


>gi|5453666 G protein-coupled receptor 19 [Homo sapiens]
          Length = 415

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 86/346 (24%), Positives = 147/346 (42%), Gaps = 51/346 (14%)

Query: 9   ANPTPRGTLSAPNATTPWLGRDEELAKV-EIGVLATVLVL-------ATGGNLAVLLTLG 60
           A P P   L   +    W+    +L  V + G +AT  +        +  GN  V L + 
Sbjct: 32  ATPLPSQYLMELSEEHSWMSNQTDLHYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIH 91

Query: 61  QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA 120
           +  R +S  + FV+ +A  DL +++      LL   T R+      C+ V+Y Q L+   
Sbjct: 92  RSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGV 151

Query: 121 STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG 180
             Y+LL++ +DR+  + +PL S +   +    +IAA W+  A F  P +F +       G
Sbjct: 152 QIYVLLSICIDRFYTIVYPL-SFKVSREKAKKMIAASWIFDAGFVTPVLFFY-------G 203

Query: 181 SGVLDCWADFGFP--WGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWR 238
           S   D   ++  P  W   AY     L  FV+P  ++   Y           KV    WR
Sbjct: 204 SN-WDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQ----------KVIKYIWR 252

Query: 239 VGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFF 298
           +G  G RT  R                  ++N + R K++T+KM  ++ L ++  W PF 
Sbjct: 253 IGTDG-RTVRR------------------TMNIVPRTKVKTIKMFLILNLLFLLSWLPFH 293

Query: 299 SVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSH 344
             Q+W   ++   D   +++ FT    +   +S   P +Y  +N++
Sbjct: 294 VAQLWHPHEQ---DYKKSSLVFTAITWISFSSSASKPTLYSIYNAN 336


>gi|21426829 prokineticin receptor 2 [Homo sapiens]
          Length = 384

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 72/282 (25%), Positives = 130/282 (46%), Gaps = 58/282 (20%)

Query: 34  AKVEIGVLATVLVLATG-GNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVAL------- 85
           AK+ IG+    ++L  G GN   +  L +  + R+  +L + +LA++D  VA+       
Sbjct: 52  AKIVIGIALAGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEM 111

Query: 86  -FQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQ 144
            + V+ QL W+  +      +LC +V YL+ +S++ ST  LLA+ +DRYLA+ HPL+  +
Sbjct: 112 DYYVVRQLSWEHGH------VLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKP-R 164

Query: 145 QPGQSTYLLIAAPWLLAAIFSLPQVFIFS--LREVIQGSGVLDCWADFGFPWGPRAYLTW 202
              Q+   LIA  W+++ + ++P  +  +  +  +++    + C    G  W     L +
Sbjct: 165 MNYQTASFLIALVWMVSILIAIPSAYFATETVLFIVKSQEKIFC----GQIWPVDQQLYY 220

Query: 203 TTLAIFVL------PVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLA 256
            +  +F+       PV  +T CY+ I  E+          W     G++T          
Sbjct: 221 KSYFLFIFGVEFVGPVVTMTLCYARISREL----------WFKAVPGFQT---------- 260

Query: 257 ATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFF 298
                       I    R + +TV +   I+ AY+ CWAPF+
Sbjct: 261 ----------EQIRKRLRCRRKTVLVLMCILTAYVLCWAPFY 292


>gi|20373179 G protein-coupled receptor 73 [Homo sapiens]
          Length = 393

 Score = 92.4 bits (228), Expect = 7e-19
 Identities = 73/282 (25%), Positives = 129/282 (45%), Gaps = 58/282 (20%)

Query: 34  AKVEIGVLATVLVLATG-GNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVAL------- 85
           AK+ IG+    ++L  G GN   +  L +  + R+  +L + +LA++D  VA+       
Sbjct: 61  AKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEM 120

Query: 86  -FQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQ 144
            + V+ QL W+  +      +LC +V YL+ +S++ ST  LLA+ +DRYLA+ HPLR  +
Sbjct: 121 DYYVVRQLSWEHGH------VLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRP-R 173

Query: 145 QPGQSTYLLIAAPWLLAAIFSLPQVFIFS--LREVIQGSGVLDCWADFGFPWGPRAYLTW 202
              Q+   LIA  W ++ + ++P  +  +  +  +++    + C    G  W     L +
Sbjct: 174 MKCQTATGLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFC----GQIWPVDQQLYY 229

Query: 203 TTLAIFVL------PVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLA 256
            +  +F+       PV  +T CY+ I  E+          W     G++T          
Sbjct: 230 KSYFLFIFGIEFVGPVVTMTLCYARISREL----------WFKAVPGFQT---------- 269

Query: 257 ATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFF 298
                       I    R + +TV +   I+ AY+ CWAPF+
Sbjct: 270 ----------EQIRKRLRCRRKTVLVLMCILTAYVLCWAPFY 301


>gi|222080095 orexin receptor 1 [Homo sapiens]
          Length = 425

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 92/371 (24%), Positives = 156/371 (42%), Gaps = 33/371 (8%)

Query: 36  VEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWD 95
           V I     V V+A  GN  V L + +    R+  + F+++L+L D+ V    +   LL D
Sbjct: 48  VLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVD 107

Query: 96  ITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPL--RSLQQPGQSTYLL 153
           IT  +     LC+ + YLQ +S+  +   L  + LDR+ A+CHPL  +S  +  + + L 
Sbjct: 108 ITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILG 167

Query: 154 IAAPWLLAAIFSLPQVFIFSLREVIQG--------SGVLDCWADFGFPWGPRAYLTWTTL 205
           I   W ++    +PQ  +     V+          S   + WAD  +   P+ Y +   +
Sbjct: 168 I---WAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLY---PKIYHSCFFI 221

Query: 206 AIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGL--- 262
             ++ P+ ++   Y  I  ++       T +  V     R W RPS   L    +GL   
Sbjct: 222 VTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALV-----RNWKRPS-DQLGDLEQGLSGE 275

Query: 263 --PSRVSSINTIS--RAKIRTVKMTFVIVLAYIACWAPFFSVQMWS---VWDKNAPDEDS 315
             P   + +  +   RA+ +T KM  V++L +  C+ P   + +        + A D ++
Sbjct: 276 PQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREA 335

Query: 316 TNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACC-GGPQPRMRRRLSDGSLSS 374
               FT S  L   NS  NP IY   +     +     +CC  G  P    +      S+
Sbjct: 336 VYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSA 395

Query: 375 RHTTLLTRSSC 385
            H +L  +S C
Sbjct: 396 SHKSLSLQSRC 406


>gi|4503907 galanin receptor 3 [Homo sapiens]
          Length = 368

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 105/384 (27%), Positives = 149/384 (38%), Gaps = 51/384 (13%)

Query: 40  VLATVLVLATGGNLAVLLTLGQLGRKR-----SRMHLFVLHLALTDLAVALFQVLPQLLW 94
           V A + +L T GN  VL  L Q G        S   LF+L+LA+ DL   L  V  Q   
Sbjct: 23  VFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATI 82

Query: 95  DITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRS--LQQPGQSTYL 152
                +    L+C+AV  L  L+M+AS++ L A+++DRYLAV HPLRS  L+ P ++   
Sbjct: 83  YTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTP-RNARA 141

Query: 153 LIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPV 212
            +   WLLAA+FS P +  +           +  W D       RA    T  A ++LPV
Sbjct: 142 AVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDA----RRRALDVATFAAGYLLPV 197

Query: 213 TMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTI 272
            +++  Y           +     W   G                     P+  ++    
Sbjct: 198 AVVSLAYG----------RTLRFLWAAVG---------------------PAGAAAAEAR 226

Query: 273 SRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSC 332
            RA  R  +    +   Y  CW P  ++ +   W        +T      S  L   NSC
Sbjct: 227 RRATGRAGRAMLAVAALYALCWGPHHAL-ILCFWYGRFAFSPATYACRLASHCLAYANSC 285

Query: 333 CNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLS 392
            NP +Y   + H   R  R L  CG    R RR  +  +L            CP     S
Sbjct: 286 LNPLVYALASRHFRAR-FRRLWPCG----RRRRHRARRALRRVRPASSGPPGCPGDARPS 340

Query: 393 LSLTLSGRPRPEESPRDLELADGE 416
             L   G   PE  PR+  +  GE
Sbjct: 341 GRLLAGGGQGPE--PREGPVHGGE 362


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 77/318 (24%), Positives = 131/318 (41%), Gaps = 70/318 (22%)

Query: 38  IGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDIT 97
           +G+   V V    GN  V+  + +  + ++  ++++ +LAL D  V L           T
Sbjct: 55  VGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL-----------T 103

Query: 98  YRFQGPDLL----------CRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQ-QP 146
             FQG D+L          C+ V  +   +MF ST+ L AM++DRY+A+CHP+R+L  + 
Sbjct: 104 LPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRT 163

Query: 147 GQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFP---WGPRAYLTWT 203
                 +  A W LA++  +P   + S +   +    ++C  +   P   WGP  +    
Sbjct: 164 SSKAQAVNVAIWALASVVGVPVAIMGSAQVEDE---EIECLVEIPTPQDYWGP-VFAICI 219

Query: 204 TLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLP 263
            L  F++PV +++ CYSL+   +                                 RG+ 
Sbjct: 220 FLFSFIVPVLVISVCYSLMIRRL---------------------------------RGV- 245

Query: 264 SRVSSINTISRAKIRTVKMTFVIVLAYIACWAP---FFSVQMWSVWDKNAPDEDSTNVAF 320
             +S      R   R  ++  V+V  ++ CW P   F   Q   V     P  ++     
Sbjct: 246 RLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGV----QPSSETAVAIL 301

Query: 321 TISMLLGNLNSCCNPWIY 338
                LG +NSC NP +Y
Sbjct: 302 RFCTALGYVNSCLNPILY 319


>gi|33286424 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 77/318 (24%), Positives = 131/318 (41%), Gaps = 70/318 (22%)

Query: 38  IGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDIT 97
           +G+   V V    GN  V+  + +  + ++  ++++ +LAL D  V L           T
Sbjct: 55  VGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL-----------T 103

Query: 98  YRFQGPDLL----------CRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQ-QP 146
             FQG D+L          C+ V  +   +MF ST+ L AM++DRY+A+CHP+R+L  + 
Sbjct: 104 LPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRT 163

Query: 147 GQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFP---WGPRAYLTWT 203
                 +  A W LA++  +P   + S +   +    ++C  +   P   WGP  +    
Sbjct: 164 SSKAQAVNVAIWALASVVGVPVAIMGSAQVEDE---EIECLVEIPTPQDYWGP-VFAICI 219

Query: 204 TLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLP 263
            L  F++PV +++ CYSL+   +                                 RG+ 
Sbjct: 220 FLFSFIVPVLVISVCYSLMIRRL---------------------------------RGV- 245

Query: 264 SRVSSINTISRAKIRTVKMTFVIVLAYIACWAP---FFSVQMWSVWDKNAPDEDSTNVAF 320
             +S      R   R  ++  V+V  ++ CW P   F   Q   V     P  ++     
Sbjct: 246 RLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGV----QPSSETAVAIL 301

Query: 321 TISMLLGNLNSCCNPWIY 338
                LG +NSC NP +Y
Sbjct: 302 RFCTALGYVNSCLNPILY 319


>gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
          Length = 398

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 94/378 (24%), Positives = 159/378 (42%), Gaps = 43/378 (11%)

Query: 15  GTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVL 74
           G + +P A   WL        V +   A +++L   GN  V+  + +    R+  + ++ 
Sbjct: 32  GPVPSPRAVDAWL--------VPL-FFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIA 82

Query: 75  HLALTDLAVALFQV-LPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRY 133
           +LA TD+   L  V    LL+ +     G D +C+ V Y+Q +S+ A+   L AM++DR+
Sbjct: 83  NLAATDVTFLLCCVPFTALLYPLPGWVLG-DFMCKFVNYIQQVSVQATCATLTAMSVDRW 141

Query: 134 LAVCHPLRSLQQPGQSTYLLIA-APWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGF 192
                PLR+L +      L ++ + W+ +A  S P   + +L  +  G     C   F  
Sbjct: 142 YVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAP---VLALHRLSPGPRAY-CSEAFPS 197

Query: 193 PWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSP 252
               RA+  +  LA+++LP+    ACY+ +   +                  R   RP+P
Sbjct: 198 RALERAFALYNLLALYLLPLLATCACYAAMLRHL-----------------GRVAVRPAP 240

Query: 253 STLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAP---FFSVQMWSVWDKN 309
           +  A   + L  R  ++    RAK+   ++   +VL + ACW P   F  +Q        
Sbjct: 241 ADSALQGQVLAERAGAV----RAKVS--RLVAAVVLLFAACWGPIQLFLVLQALGPAGSW 294

Query: 310 APDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRLSD 369
            P   +     T +  +   NS  NP +Y    SH   +  R +  C   +PR  RR   
Sbjct: 295 HPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSH-FRQAFRRVCPCAPRRPRRPRRPGP 353

Query: 370 GSLSSRHTTLLTRSSCPA 387
              ++ H  LL   S PA
Sbjct: 354 SDPAAPHAELLRLGSHPA 371


>gi|9506745 urotensin 2 receptor [Homo sapiens]
          Length = 389

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 109/410 (26%), Positives = 176/410 (42%), Gaps = 64/410 (15%)

Query: 11  PTPRGTLSAPNAT--TPWLGRDEELAKVEI---GVLATVL----VLATGGNLAVLLTLGQ 61
           P P G    PNAT  + W    E  +  ++   G + T+L    V+   GN   L+   +
Sbjct: 22  PEPPG---GPNATLNSSWASPTEPSSLEDLVATGTIGTLLSAMGVVGVVGNAYTLVVTCR 78

Query: 62  LGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWD-ITYRFQGPDLLCRAVKYLQVLSMFA 120
             R  + M+++V++LAL DL   L   +P ++   +T  +   D+ CR +  L  L+M A
Sbjct: 79  SLRAVASMYVYVVNLALADLLYLLS--IPFIVATYVTKEWHFGDVGCRVLFGLDFLTMHA 136

Query: 121 STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG 180
           S + L  M+ +RY AV  PL ++Q+P     LL    WLLA + +LP   + ++R V +G
Sbjct: 137 SIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLLTLP--VMLAMRLVRRG 194

Query: 181 SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG 240
              L   A     WGPRA+  + TL +F   +        L+   + +       A+R  
Sbjct: 195 PKSLCLPA-----WGPRAHRAYLTL-LFATSIAGPGLLIGLLYARLAR-------AYR-- 239

Query: 241 GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV 300
                                  S+ +S     R   R +++   IVL + AC+ PF+  
Sbjct: 240 ----------------------RSQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLW 277

Query: 301 QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIY----MGFNSHLLPRPLRHLACC 356
           Q+ + + +      +  +   ++  L   NSC NP++Y      +  HL  R +R     
Sbjct: 278 QLLAQYHQAPLAPRTARIVNYLTTCLTYGNSCANPFLYTLLTRNYRDHLRGR-VRGPGSG 336

Query: 357 G--GPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPE 404
           G  GP P ++ R      S R    L+  S   T SL L+     RP PE
Sbjct: 337 GGRGPVPSLQPRARFQRCSGRS---LSSCSPQPTDSLVLAPAAPARPAPE 383


>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
          Length = 493

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 80/342 (23%), Positives = 147/342 (42%), Gaps = 49/342 (14%)

Query: 4   GPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL-VLATGGNLAVLLTLGQL 62
           G L D     R  L   ++  P  G    +  + I  L +++ V+   GN  V+  + + 
Sbjct: 132 GNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRY 191

Query: 63  GRKRSRMHLFVLHLALTD-LAVAL--FQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMF 119
            + ++  ++++ +LAL D LA +   FQ +  L+   T+ F    +LC+ V  +   +MF
Sbjct: 192 TKMKTATNIYIFNLALADALATSTLPFQSVNYLMG--TWPFG--TILCKIVISIDYYNMF 247

Query: 120 ASTYMLLAMTLDRYLAVCHPLRSLQ-QPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVI 178
            S + L  M++DRY+AVCHP+++L  +  ++  ++    W+L++   LP +F+ + +   
Sbjct: 248 TSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTK--- 304

Query: 179 QGSGVLDCWADFGFP--WGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQA 236
              G +DC   F  P  +          +  F++PV ++T CY L+       L++K+  
Sbjct: 305 YRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMI------LRLKS-- 356

Query: 237 WRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAP 296
                                        +S      R   R  +M  V+V  +I CW P
Sbjct: 357 --------------------------VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTP 390

Query: 297 FFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIY 338
                +        P+     V++   + LG  NSC NP +Y
Sbjct: 391 IHIYVIIKAL-VTIPETTFQTVSWHFCIALGYTNSCLNPVLY 431


>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
          Length = 400

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 80/342 (23%), Positives = 147/342 (42%), Gaps = 49/342 (14%)

Query: 4   GPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL-VLATGGNLAVLLTLGQL 62
           G L D     R  L   ++  P  G    +  + I  L +++ V+   GN  V+  + + 
Sbjct: 39  GNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRY 98

Query: 63  GRKRSRMHLFVLHLALTD-LAVAL--FQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMF 119
            + ++  ++++ +LAL D LA +   FQ +  L+   T+ F    +LC+ V  +   +MF
Sbjct: 99  TKMKTATNIYIFNLALADALATSTLPFQSVNYLMG--TWPFG--TILCKIVISIDYYNMF 154

Query: 120 ASTYMLLAMTLDRYLAVCHPLRSLQ-QPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVI 178
            S + L  M++DRY+AVCHP+++L  +  ++  ++    W+L++   LP +F+ + +   
Sbjct: 155 TSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTK--- 211

Query: 179 QGSGVLDCWADFGFP--WGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQA 236
              G +DC   F  P  +          +  F++PV ++T CY L+       L++K+  
Sbjct: 212 YRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMI------LRLKS-- 263

Query: 237 WRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAP 296
                                        +S      R   R  +M  V+V  +I CW P
Sbjct: 264 --------------------------VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTP 297

Query: 297 FFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIY 338
                +        P+     V++   + LG  NSC NP +Y
Sbjct: 298 IHIYVIIKAL-VTIPETTFQTVSWHFCIALGYTNSCLNPVLY 338


>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
          Length = 420

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 80/342 (23%), Positives = 147/342 (42%), Gaps = 49/342 (14%)

Query: 4   GPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL-VLATGGNLAVLLTLGQL 62
           G L D     R  L   ++  P  G    +  + I  L +++ V+   GN  V+  + + 
Sbjct: 39  GNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRY 98

Query: 63  GRKRSRMHLFVLHLALTD-LAVAL--FQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMF 119
            + ++  ++++ +LAL D LA +   FQ +  L+   T+ F    +LC+ V  +   +MF
Sbjct: 99  TKMKTATNIYIFNLALADALATSTLPFQSVNYLMG--TWPFG--TILCKIVISIDYYNMF 154

Query: 120 ASTYMLLAMTLDRYLAVCHPLRSLQ-QPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVI 178
            S + L  M++DRY+AVCHP+++L  +  ++  ++    W+L++   LP +F+ + +   
Sbjct: 155 TSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTK--- 211

Query: 179 QGSGVLDCWADFGFP--WGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQA 236
              G +DC   F  P  +          +  F++PV ++T CY L+       L++K+  
Sbjct: 212 YRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMI------LRLKS-- 263

Query: 237 WRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAP 296
                                        +S      R   R  +M  V+V  +I CW P
Sbjct: 264 --------------------------VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTP 297

Query: 297 FFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIY 338
                +        P+     V++   + LG  NSC NP +Y
Sbjct: 298 IHIYVIIKAL-VTIPETTFQTVSWHFCIALGYTNSCLNPVLY 338


>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
          Length = 397

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 80/342 (23%), Positives = 147/342 (42%), Gaps = 49/342 (14%)

Query: 4   GPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL-VLATGGNLAVLLTLGQL 62
           G L D     R  L   ++  P  G    +  + I  L +++ V+   GN  V+  + + 
Sbjct: 39  GNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRY 98

Query: 63  GRKRSRMHLFVLHLALTD-LAVAL--FQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMF 119
            + ++  ++++ +LAL D LA +   FQ +  L+   T+ F    +LC+ V  +   +MF
Sbjct: 99  TKMKTATNIYIFNLALADALATSTLPFQSVNYLMG--TWPFG--TILCKIVISIDYYNMF 154

Query: 120 ASTYMLLAMTLDRYLAVCHPLRSLQ-QPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVI 178
            S + L  M++DRY+AVCHP+++L  +  ++  ++    W+L++   LP +F+ + +   
Sbjct: 155 TSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTK--- 211

Query: 179 QGSGVLDCWADFGFP--WGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQA 236
              G +DC   F  P  +          +  F++PV ++T CY L+       L++K+  
Sbjct: 212 YRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMI------LRLKS-- 263

Query: 237 WRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAP 296
                                        +S      R   R  +M  V+V  +I CW P
Sbjct: 264 --------------------------VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTP 297

Query: 297 FFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIY 338
                +        P+     V++   + LG  NSC NP +Y
Sbjct: 298 IHIYVIIKAL-VTIPETTFQTVSWHFCIALGYTNSCLNPVLY 338


>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
          Length = 403

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 80/342 (23%), Positives = 147/342 (42%), Gaps = 49/342 (14%)

Query: 4   GPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL-VLATGGNLAVLLTLGQL 62
           G L D     R  L   ++  P  G    +  + I  L +++ V+   GN  V+  + + 
Sbjct: 39  GNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRY 98

Query: 63  GRKRSRMHLFVLHLALTD-LAVAL--FQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMF 119
            + ++  ++++ +LAL D LA +   FQ +  L+   T+ F    +LC+ V  +   +MF
Sbjct: 99  TKMKTATNIYIFNLALADALATSTLPFQSVNYLMG--TWPFG--TILCKIVISIDYYNMF 154

Query: 120 ASTYMLLAMTLDRYLAVCHPLRSLQ-QPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVI 178
            S + L  M++DRY+AVCHP+++L  +  ++  ++    W+L++   LP +F+ + +   
Sbjct: 155 TSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTK--- 211

Query: 179 QGSGVLDCWADFGFP--WGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQA 236
              G +DC   F  P  +          +  F++PV ++T CY L+       L++K+  
Sbjct: 212 YRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMI------LRLKS-- 263

Query: 237 WRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAP 296
                                        +S      R   R  +M  V+V  +I CW P
Sbjct: 264 --------------------------VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTP 297

Query: 297 FFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIY 338
                +        P+     V++   + LG  NSC NP +Y
Sbjct: 298 IHIYVIIKAL-VTIPETTFQTVSWHFCIALGYTNSCLNPVLY 338


>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
          Length = 406

 Score = 89.0 bits (219), Expect = 8e-18
 Identities = 80/342 (23%), Positives = 147/342 (42%), Gaps = 49/342 (14%)

Query: 4   GPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL-VLATGGNLAVLLTLGQL 62
           G L D     R  L   ++  P  G    +  + I  L +++ V+   GN  V+  + + 
Sbjct: 39  GNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRY 98

Query: 63  GRKRSRMHLFVLHLALTD-LAVAL--FQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMF 119
            + ++  ++++ +LAL D LA +   FQ +  L+   T+ F    +LC+ V  +   +MF
Sbjct: 99  TKMKTATNIYIFNLALADALATSTLPFQSVNYLMG--TWPFG--TILCKIVISIDYYNMF 154

Query: 120 ASTYMLLAMTLDRYLAVCHPLRSLQ-QPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVI 178
            S + L  M++DRY+AVCHP+++L  +  ++  ++    W+L++   LP +F+ + +   
Sbjct: 155 TSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTK--- 211

Query: 179 QGSGVLDCWADFGFP--WGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQA 236
              G +DC   F  P  +          +  F++PV ++T CY L+       L++K+  
Sbjct: 212 YRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMI------LRLKS-- 263

Query: 237 WRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAP 296
                                        +S      R   R  +M  V+V  +I CW P
Sbjct: 264 --------------------------VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTP 297

Query: 297 FFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIY 338
                +        P+     V++   + LG  NSC NP +Y
Sbjct: 298 IHIYVIIKAL-VTIPETTFQTVSWHFCIALGYTNSCLNPVLY 338


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,084,147
Number of Sequences: 37866
Number of extensions: 754840
Number of successful extensions: 3987
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 426
Number of HSP's successfully gapped in prelim test: 321
Number of HSP's that attempted gapping in prelim test: 2805
Number of HSP's gapped (non-prelim): 1003
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.