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Search of human proteins with 44890050
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|44890050 stathmin 1 isoform a [Homo sapiens]
(149 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|44890052 stathmin 1 isoform a [Homo sapiens] 288 2e-78
gi|44890050 stathmin 1 isoform a [Homo sapiens] 288 2e-78
gi|5031851 stathmin 1 isoform a [Homo sapiens] 288 2e-78
gi|224451142 stathmin 1 isoform b [Homo sapiens] 241 1e-64
gi|21361947 stathmin-like 4 [Homo sapiens] 195 1e-50
gi|34850061 superiorcervical ganglia, neural specific 10 [Homo s... 190 3e-49
gi|14670375 SCG10-like-protein [Homo sapiens] 179 6e-46
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 2e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 49 2e-06
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 46 1e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 46 1e-05
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 45 2e-05
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 45 2e-05
gi|38044112 restin isoform b [Homo sapiens] 45 3e-05
gi|4506751 restin isoform a [Homo sapiens] 45 3e-05
gi|154354979 myosin X [Homo sapiens] 45 3e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 45 3e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 44 4e-05
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 44 5e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 44 7e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 7e-05
gi|24307965 UBX domain containing 2 [Homo sapiens] 43 9e-05
gi|148746195 trichohyalin [Homo sapiens] 43 1e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 42 1e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 42 1e-04
gi|4506467 radixin [Homo sapiens] 42 1e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 42 2e-04
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 42 2e-04
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 42 2e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 42 2e-04
>gi|44890052 stathmin 1 isoform a [Homo sapiens]
Length = 149
Score = 288 bits (736), Expect = 2e-78
Identities = 149/149 (100%), Positives = 149/149 (100%)
Query: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER
Sbjct: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
Query: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL
Sbjct: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
Query: 121 ERLREKDKHIEEVRKNKESKDPADETEAD 149
ERLREKDKHIEEVRKNKESKDPADETEAD
Sbjct: 121 ERLREKDKHIEEVRKNKESKDPADETEAD 149
>gi|44890050 stathmin 1 isoform a [Homo sapiens]
Length = 149
Score = 288 bits (736), Expect = 2e-78
Identities = 149/149 (100%), Positives = 149/149 (100%)
Query: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER
Sbjct: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
Query: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL
Sbjct: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
Query: 121 ERLREKDKHIEEVRKNKESKDPADETEAD 149
ERLREKDKHIEEVRKNKESKDPADETEAD
Sbjct: 121 ERLREKDKHIEEVRKNKESKDPADETEAD 149
>gi|5031851 stathmin 1 isoform a [Homo sapiens]
Length = 149
Score = 288 bits (736), Expect = 2e-78
Identities = 149/149 (100%), Positives = 149/149 (100%)
Query: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER
Sbjct: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
Query: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL
Sbjct: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
Query: 121 ERLREKDKHIEEVRKNKESKDPADETEAD 149
ERLREKDKHIEEVRKNKESKDPADETEAD
Sbjct: 121 ERLREKDKHIEEVRKNKESKDPADETEAD 149
>gi|224451142 stathmin 1 isoform b [Homo sapiens]
Length = 174
Score = 241 bits (616), Expect = 1e-64
Identities = 126/126 (100%), Positives = 126/126 (100%)
Query: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER
Sbjct: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
Query: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL
Sbjct: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
Query: 121 ERLREK 126
ERLREK
Sbjct: 121 ERLREK 126
>gi|21361947 stathmin-like 4 [Homo sapiens]
Length = 216
Score = 195 bits (495), Expect = 1e-50
Identities = 101/140 (72%), Positives = 117/140 (83%)
Query: 4 SDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKS 63
SD++V EL K SGQ+FE+IL P S + VPEF S P+++D SLEEIQKKLEAAEERRK
Sbjct: 75 SDMEVIELNKCTSGQSFEVILKPPSFDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKY 134
Query: 64 HEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERL 123
EAE+LK LAEKREHE+EV+QKAIEENNNF KMA+EKL KME+NKENREA +AA LERL
Sbjct: 135 QEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERL 194
Query: 124 REKDKHIEEVRKNKESKDPA 143
+EKDKH EEVRKNKE K+ A
Sbjct: 195 QEKDKHAEEVRKNKELKEEA 214
>gi|34850061 superiorcervical ganglia, neural specific 10 [Homo
sapiens]
Length = 179
Score = 190 bits (483), Expect = 3e-49
Identities = 100/134 (74%), Positives = 114/134 (85%)
Query: 5 DIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSH 64
D++VK++ KRASGQAFELIL P S S L+ PKKKDLSLEEIQKKLEAAEERRKS
Sbjct: 39 DMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQ 98
Query: 65 EAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLR 124
EA+VLKQLAEKREHE+EVLQKA+EENNNFSKMAEEKL KME KENREA +AA +ERL+
Sbjct: 99 EAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQ 158
Query: 125 EKDKHIEEVRKNKE 138
EK++H EVR+NKE
Sbjct: 159 EKERHAAEVRRNKE 172
>gi|14670375 SCG10-like-protein [Homo sapiens]
Length = 180
Score = 179 bits (455), Expect = 6e-46
Identities = 94/139 (67%), Positives = 116/139 (83%), Gaps = 3/139 (2%)
Query: 5 DIQVKELEKRASGQAFELILSPRSKESVPEFPL--SPPKKKDLSLEEIQKKLEAAEERRK 62
D++VK+L+KRASGQ+FE+IL S S PE P+ SPPKKKD SLEE+QK+LEAAEERRK
Sbjct: 39 DMEVKQLDKRASGQSFEVILKSPSDLS-PESPMLSSPPKKKDTSLEELQKRLEAAEERRK 97
Query: 63 SHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLER 122
+ EA+VLKQLAE+REHE+EVL KA+EENNNFS+ AEEKL +KME +KE REA +AA ER
Sbjct: 98 TQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRER 157
Query: 123 LREKDKHIEEVRKNKESKD 141
LREK+ H EVR+NKE ++
Sbjct: 158 LREKELHAAEVRRNKEQRE 176
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 48.9 bits (115), Expect = 2e-06
Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 4/115 (3%)
Query: 27 RSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKA 86
R K+ E + + K+ +E +K+ E E RK E E ++ E+++ E+ K
Sbjct: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRER----KQ 170
Query: 87 IEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKD 141
+ E K E K K E N++ R+ + K R R+K++ +E RK + KD
Sbjct: 171 VGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKD 225
Score = 42.7 bits (99), Expect = 1e-04
Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 8/99 (8%)
Query: 47 LEEIQKKLEAAEERRKSHEAEVLKQLAE----KREHEKEVLQKAIEENNNFSKMAEEKLT 102
+ E ++++E +E +K E+E K+ E KRE EKE ++ ++ + EE+
Sbjct: 38 IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER 97
Query: 103 HKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKD 141
K KEN+E + K R+K + E R +KE K+
Sbjct: 98 KKRRREKENKEGEEKEK----RKKKEKKERGRTSKEGKE 132
Score = 39.7 bits (91), Expect = 0.001
Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 2/141 (1%)
Query: 9 KELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEV 68
+E EKR + E KE E ++K E+ K+ E E+R+K + E
Sbjct: 64 REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKER 123
Query: 69 LKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDK 128
+ E +E E++ +K E K E + + + K+ Q+ K E +EK++
Sbjct: 124 GRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKER 183
Query: 129 HIEEVRKN--KESKDPADETE 147
+ R+ KE K + E
Sbjct: 184 KERKKRERNRKERKKERERKE 204
Score = 37.0 bits (84), Expect = 0.006
Identities = 25/106 (23%), Positives = 52/106 (49%), Gaps = 2/106 (1%)
Query: 38 SPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMA 97
S KK+ E+ +++ E +R + + + ++ E+RE +K +K +E K
Sbjct: 57 SERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRK 116
Query: 98 EEKLTHKMEANKE--NREAQMAAKLERLREKDKHIEEVRKNKESKD 141
+++ + +KE RE + K E +E+++ EE K +E K+
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162
Score = 36.6 bits (83), Expect = 0.008
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 49 EIQKKLEAAEERRKSHEAEVLKQLAEKR---EHEKEVLQKAIEENNNFSKMAEEKLTHKM 105
E +K+ E+R++ E E ++ +K E +KE ++ +K EEK K
Sbjct: 58 ERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKK 117
Query: 106 EANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 149
+ KE K ER R++++ EE RK +E K E E +
Sbjct: 118 KEKKERGRTSKEGK-ERERKEERKREE-RKERERKKEEREKERE 159
Score = 33.1 bits (74), Expect = 0.089
Identities = 29/118 (24%), Positives = 47/118 (39%), Gaps = 9/118 (7%)
Query: 9 KELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEV 68
KE KR + E R KE ++K+ E ++ E EER++ E
Sbjct: 136 KEERKREERKERERKKEEREKER---------ERKERKKRERKQVGEKEEERKEKERKER 186
Query: 69 LKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREK 126
K+ ++E +KE +K E K EE+ + + + N + K ER K
Sbjct: 187 KKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 48.9 bits (115), Expect = 2e-06
Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 10/112 (8%)
Query: 37 LSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKM 96
+ P +K+ LE +++K EA + RR+ E + ++L E + +E L+K ++ +M
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQM 587
Query: 97 AEEK----------LTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKE 138
EEK + K E KE R A+ AK + +K + +E RK +E
Sbjct: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
Score = 45.4 bits (106), Expect = 2e-05
Identities = 39/139 (28%), Positives = 61/139 (43%), Gaps = 10/139 (7%)
Query: 7 QVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHE- 65
Q+KE +K+ Q F I K KKK + KK+E E RRK E
Sbjct: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA-----KKMEEVEARRKQEEE 640
Query: 66 ---AEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK-LTHKMEANKENREAQMAAKLE 121
L+Q E+R H++ + +K EE K AE K L + E + +E + + E
Sbjct: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
Query: 122 RLREKDKHIEEVRKNKESK 140
+ R + + E+ R+ E +
Sbjct: 701 QERREQERREQERQLAEQE 719
Score = 43.1 bits (100), Expect = 9e-05
Identities = 39/148 (26%), Positives = 77/148 (52%), Gaps = 12/148 (8%)
Query: 9 KELEKRASGQAFELILSPRSKESVPEFP--LSPPKKKDLSLEEIQKKLEAAEER-RKSHE 65
++ +K+A+ + E + + R +E L +++ E +QKK E +ER RK+ E
Sbjct: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 676
Query: 66 AEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKME-ANKENREAQMAAKLER-L 123
A K+LAE+RE E+ ++ +E + +E+ + + A +E R Q + ER L
Sbjct: 677 A---KRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 733
Query: 124 REKDKHI----EEVRKNKESKDPADETE 147
+E++K + E++++ E K +E +
Sbjct: 734 QEREKALRLQKEQLQRELEEKKKKEEQQ 761
Score = 42.4 bits (98), Expect = 1e-04
Identities = 27/106 (25%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 37 LSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAE---KREHEKEVLQKAIEENNNF 93
L+ ++++ +E +++ +ERR+ E +QLAE +RE E+ ++ ++E
Sbjct: 680 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 739
Query: 94 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKES 139
++ +E+L ++E K+ E Q RL E+ E+ +K KE+
Sbjct: 740 LRLQKEQLQRELEEKKKKEEQQ------RLAERQLQEEQEKKAKEA 779
Score = 39.7 bits (91), Expect = 0.001
Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 45 LSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHK 104
L EE +K+ A ER + + E KQ+ +K E +KA EE K ++ K
Sbjct: 568 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 627
Query: 105 ME----ANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
ME K+ EA+ L++ E+ +H E ++K KE +
Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE 667
Score = 39.3 bits (90), Expect = 0.001
Identities = 26/111 (23%), Positives = 55/111 (49%), Gaps = 14/111 (12%)
Query: 41 KKKDLSLEEIQKKLEAA-------EERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF 93
KKK+ E ++K EA +ERR+ E ++ E+RE E+ E+
Sbjct: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR------EQERQL 715
Query: 94 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPAD 144
++ + +++A +E +E + A +L++ + + +EE +K +E + A+
Sbjct: 716 AEQERRREQERLQAERELQEREKALRLQK-EQLQRELEEKKKKEEQQRLAE 765
Score = 28.5 bits (62), Expect = 2.2
Identities = 22/104 (21%), Positives = 43/104 (41%), Gaps = 1/104 (0%)
Query: 37 LSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKM 96
L PP+ K S K+ R H + + L + V++ I+ N
Sbjct: 471 LQPPRSKTPSSPCPASKV-VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
Query: 97 AEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
+EK ++E + EA+ + + +K + +EEV+ +E +
Sbjct: 530 PKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREER 573
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 45.8 bits (107), Expect = 1e-05
Identities = 36/141 (25%), Positives = 75/141 (53%), Gaps = 11/141 (7%)
Query: 7 QVKELEKRASGQ---AFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKL-EAAEERRK 62
Q +EL++ GQ A + S +++ + E + +++ LEE+Q++L EA + K
Sbjct: 388 QHRELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVK 447
Query: 63 SHEAEVLKQLAEKR--EHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
+ E ++A+ R E E+E L++ ++ K +E+ + + KE + +MA +
Sbjct: 448 ARRDEESVRIAQTRLLEEEEEKLKQLMQ-----LKEEQERYIERAQQEKEELQQEMAQQS 502
Query: 121 ERLREKDKHIEEVRKNKESKD 141
L++ + +EEVR+N++ D
Sbjct: 503 RSLQQAQQQLEEVRQNRQRAD 523
Score = 33.5 bits (75), Expect = 0.068
Identities = 21/87 (24%), Positives = 44/87 (50%), Gaps = 3/87 (3%)
Query: 48 EEIQKKLEAAE--ERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKM 105
EE ++KL+ E + + +L++ E+R + LQ+A+E ++ A + +M
Sbjct: 355 EEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEM 414
Query: 106 EANKENREAQMAAKLERLREKDKHIEE 132
E KE A+ +++ L E + ++E
Sbjct: 415 EL-KEEEAARQRQRIKELEEMQQRLQE 440
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 45.8 bits (107), Expect = 1e-05
Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 10/108 (9%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100
+K+ LE +++K EA + RR+ E + ++L E + +E L+K ++ +M EEK
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595
Query: 101 ----------LTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKE 138
+ K E KE R A+ AK + +K + +E RK +E
Sbjct: 596 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 643
Score = 45.4 bits (106), Expect = 2e-05
Identities = 39/139 (28%), Positives = 61/139 (43%), Gaps = 10/139 (7%)
Query: 7 QVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHE- 65
Q+KE +K+ Q F I K KKK + KK+E E RRK E
Sbjct: 590 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA-----KKMEEVEARRKQEEE 644
Query: 66 ---AEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK-LTHKMEANKENREAQMAAKLE 121
L+Q E+R H++ + +K EE K AE K L + E + +E + + E
Sbjct: 645 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 704
Query: 122 RLREKDKHIEEVRKNKESK 140
+ R + + E+ R+ E +
Sbjct: 705 QERREQERREQERQLAEQE 723
Score = 43.1 bits (100), Expect = 9e-05
Identities = 39/148 (26%), Positives = 77/148 (52%), Gaps = 12/148 (8%)
Query: 9 KELEKRASGQAFELILSPRSKESVPEFP--LSPPKKKDLSLEEIQKKLEAAEER-RKSHE 65
++ +K+A+ + E + + R +E L +++ E +QKK E +ER RK+ E
Sbjct: 621 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 680
Query: 66 AEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKME-ANKENREAQMAAKLER-L 123
A K+LAE+RE E+ ++ +E + +E+ + + A +E R Q + ER L
Sbjct: 681 A---KRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 737
Query: 124 REKDKHI----EEVRKNKESKDPADETE 147
+E++K + E++++ E K +E +
Sbjct: 738 QEREKALRLQKEQLQRELEEKKKKEEQQ 765
Score = 42.4 bits (98), Expect = 1e-04
Identities = 27/106 (25%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 37 LSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAE---KREHEKEVLQKAIEENNNF 93
L+ ++++ +E +++ +ERR+ E +QLAE +RE E+ ++ ++E
Sbjct: 684 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 743
Query: 94 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKES 139
++ +E+L ++E K+ E Q RL E+ E+ +K KE+
Sbjct: 744 LRLQKEQLQRELEEKKKKEEQQ------RLAERQLQEEQEKKAKEA 783
Score = 39.7 bits (91), Expect = 0.001
Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 45 LSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHK 104
L EE +K+ A ER + + E KQ+ +K E +KA EE K ++ K
Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 631
Query: 105 ME----ANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
ME K+ EA+ L++ E+ +H E ++K KE +
Sbjct: 632 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE 671
Score = 39.3 bits (90), Expect = 0.001
Identities = 26/111 (23%), Positives = 55/111 (49%), Gaps = 14/111 (12%)
Query: 41 KKKDLSLEEIQKKLEAA-------EERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF 93
KKK+ E ++K EA +ERR+ E ++ E+RE E+ E+
Sbjct: 666 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR------EQERQL 719
Query: 94 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPAD 144
++ + +++A +E +E + A +L++ + + +EE +K +E + A+
Sbjct: 720 AEQERRREQERLQAERELQEREKALRLQK-EQLQRELEEKKKKEEQQRLAE 769
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 45.1 bits (105), Expect = 2e-05
Identities = 28/118 (23%), Positives = 60/118 (50%), Gaps = 3/118 (2%)
Query: 27 RSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKA 86
RS +S S K+ LS ++I+++ E +R++ E ++ E+ + E+E +A
Sbjct: 594 RSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEA 653
Query: 87 IEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLR---EKDKHIEEVRKNKESKD 141
E +++ E+L + + + RE +LER R E+++ E+ R ++E ++
Sbjct: 654 FHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREE 711
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 45.1 bits (105), Expect = 2e-05
Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 12/128 (9%)
Query: 29 KESVPEFPLSPPKKKDLSLEEIQKKLEAAEER--------RKSHEAEVLKQLAEKREHEK 80
K+ E PK + LSLEE+ K +A EE + EAE LK +R+ E
Sbjct: 126 KDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALK----RRQQEV 181
Query: 81 EVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
E Q+ +EE K ++ +E +E + ++ER ++ E +K +E K
Sbjct: 182 EERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEK 241
Query: 141 DPADETEA 148
D + E A
Sbjct: 242 DKSKELHA 249
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 44.7 bits (104), Expect = 3e-05
Identities = 43/151 (28%), Positives = 71/151 (47%), Gaps = 15/151 (9%)
Query: 10 ELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVL 69
E+E + Q E + E++ + K+K+ SLE I+ KL+ AE++ + L
Sbjct: 627 EIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTL 686
Query: 70 KQL--AEKREHEKEVLQKAIEEN----NNFS---KMAEEKL-----THKMEANKENREAQ 115
+L AE + E EVLQ E +NF+ K EEKL K + ++ +
Sbjct: 687 NKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKK 746
Query: 116 MAAKLERLREKDKHIEEVRKNKESKDPADET 146
+ +LE ++ KH+ E+ KN ES + T
Sbjct: 747 LRQQLEAAEKQIKHL-EIEKNAESSKASSIT 776
Score = 30.8 bits (68), Expect = 0.44
Identities = 27/120 (22%), Positives = 54/120 (45%), Gaps = 29/120 (24%)
Query: 48 EEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF-------------- 93
+E++ + E A K+ E+L+ L + ++ L+ A EEN+
Sbjct: 977 QELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKA 1036
Query: 94 --SKMAEEKLTHKMEANKENRE------------AQMAAKLERLREKD-KHIEEVRKNKE 138
++ AE+ + + KE E A++ +L+ L+E + K++EE+ K+KE
Sbjct: 1037 KAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKE 1096
Score = 30.4 bits (67), Expect = 0.58
Identities = 18/90 (20%), Positives = 40/90 (44%)
Query: 58 EERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMA 117
E R K + E L+ K LQK+IE+ ++ ++++ K E K+ E +++
Sbjct: 904 ELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS 963
Query: 118 AKLERLREKDKHIEEVRKNKESKDPADETE 147
+++ +E++ E +T+
Sbjct: 964 DLEKKMETSHNQCQELKARYERATSETKTK 993
Score = 29.6 bits (65), Expect = 0.98
Identities = 23/101 (22%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEV---LQKAIEENNNFSKMA 97
K+ + L +++KK+E + + + +A + +E + +E+ LQK + + + K A
Sbjct: 956 KELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGA 1015
Query: 98 EEKLTHKMEANKENREAQMAAKLERLREKDKHI-EEVRKNK 137
E+ + ++ +E R+ AK + E I E++ K K
Sbjct: 1016 REENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK 1056
Score = 28.1 bits (61), Expect = 2.9
Identities = 23/110 (20%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Query: 43 KDLSLEEIQKKLEAA---EERRKSHEAEV--LKQLAEKREHEKEVLQKAIEENNNFSKMA 97
+D++++ Q + EAA EE +K E ++ L++ E ++ + L+ E + +K
Sbjct: 934 EDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTK 993
Query: 98 EEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETE 147
E++ ++ + E ++ E + +EE+RK + A E
Sbjct: 994 HEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAE 1043
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 44.7 bits (104), Expect = 3e-05
Identities = 43/151 (28%), Positives = 71/151 (47%), Gaps = 15/151 (9%)
Query: 10 ELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVL 69
E+E + Q E + E++ + K+K+ SLE I+ KL+ AE++ + L
Sbjct: 662 EIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTL 721
Query: 70 KQL--AEKREHEKEVLQKAIEEN----NNFS---KMAEEKL-----THKMEANKENREAQ 115
+L AE + E EVLQ E +NF+ K EEKL K + ++ +
Sbjct: 722 NKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKK 781
Query: 116 MAAKLERLREKDKHIEEVRKNKESKDPADET 146
+ +LE ++ KH+ E+ KN ES + T
Sbjct: 782 LRQQLEAAEKQIKHL-EIEKNAESSKASSIT 811
Score = 30.8 bits (68), Expect = 0.44
Identities = 27/120 (22%), Positives = 54/120 (45%), Gaps = 29/120 (24%)
Query: 48 EEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF-------------- 93
+E++ + E A K+ E+L+ L + ++ L+ A EEN+
Sbjct: 1012 QELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKA 1071
Query: 94 --SKMAEEKLTHKMEANKENRE------------AQMAAKLERLREKD-KHIEEVRKNKE 138
++ AE+ + + KE E A++ +L+ L+E + K++EE+ K+KE
Sbjct: 1072 KAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKE 1131
Score = 30.4 bits (67), Expect = 0.58
Identities = 18/90 (20%), Positives = 40/90 (44%)
Query: 58 EERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMA 117
E R K + E L+ K LQK+IE+ ++ ++++ K E K+ E +++
Sbjct: 939 ELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS 998
Query: 118 AKLERLREKDKHIEEVRKNKESKDPADETE 147
+++ +E++ E +T+
Sbjct: 999 DLEKKMETSHNQCQELKARYERATSETKTK 1028
Score = 30.0 bits (66), Expect = 0.75
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 11/107 (10%)
Query: 47 LEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKME 106
LEE ++K+E + R + E + K E + + K +E++ F K +KL ++E
Sbjct: 431 LEEEKRKVEDLQFRVE--EESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELE 488
Query: 107 ANKENREAQMAAKLERLR-EKD-----KHIEEVRKNKESKDPADETE 147
+ R A ++ K + EKD + + E+R+ ES PA + +
Sbjct: 489 ---DTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVD 532
Score = 29.6 bits (65), Expect = 0.98
Identities = 23/101 (22%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEV---LQKAIEENNNFSKMA 97
K+ + L +++KK+E + + + +A + +E + +E+ LQK + + + K A
Sbjct: 991 KELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGA 1050
Query: 98 EEKLTHKMEANKENREAQMAAKLERLREKDKHI-EEVRKNK 137
E+ + ++ +E R+ AK + E I E++ K K
Sbjct: 1051 REENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK 1091
Score = 28.1 bits (61), Expect = 2.9
Identities = 23/110 (20%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Query: 43 KDLSLEEIQKKLEAA---EERRKSHEAEV--LKQLAEKREHEKEVLQKAIEENNNFSKMA 97
+D++++ Q + EAA EE +K E ++ L++ E ++ + L+ E + +K
Sbjct: 969 EDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTK 1028
Query: 98 EEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETE 147
E++ ++ + E ++ E + +EE+RK + A E
Sbjct: 1029 HEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAE 1078
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 44.7 bits (104), Expect = 3e-05
Identities = 31/103 (30%), Positives = 54/103 (52%), Gaps = 17/103 (16%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAE--KREHEKEVLQKAIEENNNFSKMAE 98
KKK E+ +++ E E R+ EAE+ Q E +++ E E LQK+ E
Sbjct: 821 KKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKS---------QKE 871
Query: 99 EKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKD 141
+LT ++E KEN++ + +LE K IE++++ KE ++
Sbjct: 872 AELTRELEKQKENKQVEEILRLE------KEIEDLQRMKEQQE 908
Score = 38.9 bits (89), Expect = 0.002
Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 7/86 (8%)
Query: 58 EERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEA-NKENREAQM 116
EE++K E E K+ E+RE E+E + + E + ++EA K +EA++
Sbjct: 819 EEKKKQEEEEKKKREEEERERERERREAELRAQQE----EETRKQQELEALQKSQKEAEL 874
Query: 117 AAKLERLREKDKHIEEV-RKNKESKD 141
+LE+ +E +K +EE+ R KE +D
Sbjct: 875 TRELEKQKE-NKQVEEILRLEKEIED 899
Score = 33.9 bits (76), Expect = 0.052
Identities = 27/103 (26%), Positives = 53/103 (51%), Gaps = 12/103 (11%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEK----REHEKEVLQKAIEENNNFSKM 96
++++ E + + + EE RK E E L++ ++ RE EK+ K +EE K
Sbjct: 837 RERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKE 896
Query: 97 AEEKLTHKMEANKENREAQMA-AKLERLREKDKHIEEVRKNKE 138
E+ ++ KE +E + A L++L+E + +E+R+ +E
Sbjct: 897 IED-----LQRMKEQQELSLTEASLQKLQE--RRDQELRRLEE 932
Score = 32.3 bits (72), Expect = 0.15
Identities = 27/118 (22%), Positives = 54/118 (45%), Gaps = 9/118 (7%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQ----LAEKREHEKEVLQKAIEENNNFSKM 96
K K E +++KLE E SH A V++ ++++ K + I + N + +
Sbjct: 721 KTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFL 780
Query: 97 AEEKLTHKMEAN---KENREAQMAAKLER--LREKDKHIEEVRKNKESKDPADETEAD 149
+ H +A ++ Q+A ++ R L EK + E+ ++ +E K +E E +
Sbjct: 781 LRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERE 838
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 44.7 bits (104), Expect = 3e-05
Identities = 26/103 (25%), Positives = 52/103 (50%)
Query: 45 LSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHK 104
L + E Q E ER + E E K+L +++E E+E ++ E + EK K
Sbjct: 492 LGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEK 551
Query: 105 MEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETE 147
++ R+ + +LER +EK+K ++++++ ++ + E E
Sbjct: 552 QREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKERE 594
Score = 41.6 bits (96), Expect = 2e-04
Identities = 36/144 (25%), Positives = 71/144 (49%), Gaps = 21/144 (14%)
Query: 11 LEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLK 70
LEK+ S + E+ R KE E L ++ +E +K+ E ER++ E E+ K
Sbjct: 495 LEKQPSPE--EIREREREKEREREKELEKEQE-----QEREKEREKDRERQQEKEKELEK 547
Query: 71 QLAEKREHEKE-------VLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERL 123
+ ++RE EKE L++ E+ KM E++ ++E +E E E++
Sbjct: 548 EQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLE-------EKI 600
Query: 124 REKDKHIEEVRKNKESKDPADETE 147
++ ++E + + +ES++ ++ E
Sbjct: 601 EPREPNLEPMVEKQESENSCNKEE 624
Score = 39.3 bits (90), Expect = 0.001
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 44/168 (26%)
Query: 26 PRSKESVPEFPLSPPKKKDLSLE------------EIQKKLEAAEERRKSHE-------- 65
P +++VP P P K+ ++ E EI +E A +RR+ E
Sbjct: 419 PPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRK 478
Query: 66 ---AEVLKQLAEK---------------------REHEKEVLQKAIEENNNFSKMAEEKL 101
AE LK+L EK RE EKE+ ++ +E + E+
Sbjct: 479 AACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQ 538
Query: 102 THKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 149
K + ++ +E Q + ER +EK+K +E ++ ++ E E +
Sbjct: 539 QEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 44.3 bits (103), Expect = 4e-05
Identities = 41/149 (27%), Positives = 72/149 (48%), Gaps = 10/149 (6%)
Query: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
+ + ++V EK Q +++S ++ + E P +++ S +EI + EE
Sbjct: 203 IGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGS-DEISHHEKMEEED 261
Query: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
++ EAE + AE+RE K K I + + AEEK A + RE + A +
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKIADERARIE-AEEK------AAAQERERREAEER 314
Query: 121 ERLREKDKHIEEVRK--NKESKDPADETE 147
ER+RE++K E R+ +E K A+E +
Sbjct: 315 ERMREEEKRAAEERQRIKEEEKRAAEERQ 343
Score = 39.3 bits (90), Expect = 0.001
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 4/97 (4%)
Query: 7 QVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEA 66
+++EL +R E + K+ L KKK EE +K LE E+RRK EA
Sbjct: 535 RLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR---EERRKVLEEEEQRRKQEEA 591
Query: 67 E-VLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLT 102
+ L++ EKR ++E+ ++ E KM E+ L+
Sbjct: 592 DRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLS 628
Score = 37.4 bits (85), Expect = 0.005
Identities = 27/97 (27%), Positives = 50/97 (51%), Gaps = 5/97 (5%)
Query: 51 QKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKE 110
+++ AAEER++ E E K+ AE+R+ KE ++A EE ++ EE+ E +
Sbjct: 319 EEEKRAAEERQRIKEEE--KRAAEERQRIKEEEKRAAEERQ---RIKEEEKRAAEERQRA 373
Query: 111 NREAQMAAKLERLREKDKHIEEVRKNKESKDPADETE 147
E + AK+E + + E+ +E+K ++ E
Sbjct: 374 RAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVE 410
Score = 35.0 bits (79), Expect = 0.023
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 33/163 (20%)
Query: 7 QVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEA 66
++KE EKRA+ + ++ + E +++ EE +K+ +R ++ E
Sbjct: 330 RIKEEEKRAAEE----------RQRIKEEEKRAAEERQRIKEE-EKRAAEERQRARAEEE 378
Query: 67 EVLKQLAEKREHEKEVLQKAIEENN---------------NFSKMAEEKL-THKMEANKE 110
E K +KR + E + A++E N K E+KL T ++ E
Sbjct: 379 EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGE 438
Query: 111 NREAQMAAKLERLRE-----KDKHIEEVRKNKESKDPADETEA 148
+ ++ AK E+L+E K + I++ K K+ K+P +E ++
Sbjct: 439 EKGTKVQAKREKLQEDKPTFKKEEIKD-EKIKKDKEPKEEVKS 480
Score = 34.7 bits (78), Expect = 0.031
Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 49 EIQKKLEAAEERR---KSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKM 105
E K+LE RR +S E E LKQ ++ E E L+K EE + EE+ +
Sbjct: 531 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLE-EEEQRRKQE 589
Query: 106 EANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 149
EA+++ RE + + RL+E+ + K K P D D
Sbjct: 590 EADRKLREEE---EKRRLKEEIERRRAEAAEKRQKMPEDGLSDD 630
Score = 33.1 bits (74), Expect = 0.089
Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 24/127 (18%)
Query: 4 SDIQVKELE---KRASGQAFELILSPRSKESVPEFPLSPPKKKD--LSLEEIQKKLEAAE 58
+ + KE E + +G+ E + R + EF K+++ L LEE++KK E
Sbjct: 517 ASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKK---RE 573
Query: 59 ERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAA 118
ERRK E E E+R ++E +K EE EEK K E + R A+ A
Sbjct: 574 ERRKVLEEE------EQRRKQEEADRKLREE--------EEKRRLKEEIER--RRAEAAE 617
Query: 119 KLERLRE 125
K +++ E
Sbjct: 618 KRQKMPE 624
Score = 31.2 bits (69), Expect = 0.34
Identities = 28/102 (27%), Positives = 53/102 (51%), Gaps = 9/102 (8%)
Query: 42 KKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKL 101
++D + + + ++EA EE+ + E E ++ AE+RE +E ++A EE + EEK
Sbjct: 283 EQDKKIADERARIEA-EEKAAAQERE--RREAEERERMREEEKRAAEERQRIKE--EEK- 336
Query: 102 THKMEANKENREAQMAAKLERLR--EKDKHIEEVRKNKESKD 141
E + +E + A ER R E++K E R+ +++
Sbjct: 337 -RAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE 377
Score = 30.0 bits (66), Expect = 0.75
Identities = 19/88 (21%), Positives = 36/88 (40%)
Query: 55 EAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREA 114
EAA ERR+ E L+Q E+ + Q + N+ + T + ++ A
Sbjct: 36 EAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAA 95
Query: 115 QMAAKLERLREKDKHIEEVRKNKESKDP 142
+ R + K ++E + ++ DP
Sbjct: 96 FLERLARREERRQKRLQEALERQKEFDP 123
Score = 29.6 bits (65), Expect = 0.98
Identities = 37/154 (24%), Positives = 60/154 (38%), Gaps = 32/154 (20%)
Query: 27 RSKE---SVPEFPLSPPKKK---DLSLEEIQKKLEAAEERRKSHEAEVL----------- 69
R KE ++ + LS P ++ D + E +K E +E R++ +E E
Sbjct: 117 RQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND 176
Query: 70 --------KQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEAN-----KENREAQM 116
K+ EK E E+E ++ N M EEK T E K + +
Sbjct: 177 WRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSE 236
Query: 117 AAKLERLREK--DKHIEEVRKNKESKDPADETEA 148
K E RE+ D+ + +E K+ A+ A
Sbjct: 237 EPKQEEEREQGSDEISHHEKMEEEDKERAEAERA 270
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 43.9 bits (102), Expect = 5e-05
Identities = 44/138 (31%), Positives = 63/138 (45%), Gaps = 27/138 (19%)
Query: 26 PRSKESVPEFPLSPP-------------KKKDLSLEEIQKKL--------EAAEERRKSH 64
P+ S FP S P +K L L+ Q++L E E+ +
Sbjct: 303 PKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKE 362
Query: 65 EAEVLKQLAEKR-EHEKEVLQK-AIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLER 122
EA+ K+ A+K+ E EKE+ +K E+ K EK K E KE +EA + AKLE
Sbjct: 363 EAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEA-LEAKLEE 421
Query: 123 LREKDKHIEEVRKNKESK 140
R+K+ EE R +E K
Sbjct: 422 KRKKE---EEKRLREEEK 436
Score = 30.4 bits (67), Expect = 0.58
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 17/114 (14%)
Query: 9 KELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEV 68
K+L+ RA + E + KE KKK+ EE + K + E+R+ E E
Sbjct: 346 KQLKLRAEREEKEKL-----KEEAKRAKEEAKKKKE---EEKELKEKERREKREKDEKEK 397
Query: 69 LKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLER 122
++ K E KE Q+A+E +K+ E++ K E K RE + K E+
Sbjct: 398 AEKQRLKEERRKE-RQEALE-----AKLEEKR---KKEEEKRLREEEKRIKAEK 442
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 43.5 bits (101), Expect = 7e-05
Identities = 29/136 (21%), Positives = 68/136 (50%), Gaps = 3/136 (2%)
Query: 7 QVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEI--QKKLEAAEERRKSH 64
+++E E++ Q E++ K E + ++K LEE+ +K+ + E K H
Sbjct: 329 KIREQEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 65 EAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLR 124
E E +++ EKR+ E+++ ++ + +E+ + E +E +M + E++
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 125 EKDKHIEEVRKNKESK 140
E++K EE ++ ++ +
Sbjct: 448 EQEKIREEEKRQEQEE 463
Score = 35.4 bits (80), Expect = 0.018
Identities = 24/101 (23%), Positives = 54/101 (53%), Gaps = 5/101 (4%)
Query: 51 QKKLEAAEERRKSHEAEVLKQLAEKREHEKEV--LQKAIEENNNFSKMAEEKLTHKMEAN 108
Q+K+ EE+ + E ++ +Q + RE E+++ ++ I E + EEK+ + E
Sbjct: 563 QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKM 622
Query: 109 KENREAQMAAKLERLREKDKHI--EEVRKNKESKDPADETE 147
E +E +M + E++R +++ + +EVR ++ + + E
Sbjct: 623 CE-QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 34.3 bits (77), Expect = 0.040
Identities = 26/112 (23%), Positives = 54/112 (48%), Gaps = 15/112 (13%)
Query: 48 EEIQKKLEAAEERRKSHEAEVLKQLAEK------REHEKEVLQKAIEENNNFSKMAEEKL 101
E+I+++ E ++ K HE E +++ EK + H++E + I E EEK+
Sbjct: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE---EKIREQEEKMWRQEEKI 525
Query: 102 THKMEANKE------NREAQMAAKLERLREKDKHIEEVRKNKESKDPADETE 147
+ E +E +E M + E++ E+++ ++E K + ++ E E
Sbjct: 526 REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQE 577
Score = 32.7 bits (73), Expect = 0.12
Identities = 26/110 (23%), Positives = 54/110 (49%), Gaps = 14/110 (12%)
Query: 42 KKDLSLEEIQKKLEAAEERR----KSHEAEVLKQLAEKREHEKEVL---QKAIEENNNFS 94
+K+ + E+++K+ E+ R K E E +++ EKR+ ++ + ++ I E
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKI 432
Query: 95 KMAEEKL------THKMEANKENREAQMAAKLERLREKDKHIEEVRKNKE 138
+ E+K+ H+ E +E + Q ++ R EK + EE+ + KE
Sbjct: 433 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 482
Score = 32.3 bits (72), Expect = 0.15
Identities = 29/138 (21%), Positives = 61/138 (44%), Gaps = 14/138 (10%)
Query: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
M + +++ELE++ Q E I K E K+++ + +++ + E+
Sbjct: 372 MWEKEEKIRELEEKMHEQ--EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 429
Query: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
K E E E++ HE+E +++ EEK + E ++ + + ++
Sbjct: 430 EKIREQEKKMWRQEEKIHEQEKIRE------------EEKRQEQEEMWRQEEKIREQEEI 477
Query: 121 ERLREKDKHIEEVRKNKE 138
R +EK E++RK +E
Sbjct: 478 WRQKEKMHEQEKIRKQEE 495
Score = 29.3 bits (64), Expect = 1.3
Identities = 26/97 (26%), Positives = 50/97 (51%), Gaps = 9/97 (9%)
Query: 47 LEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKME 106
L+ + KL+A E E E+ +L +++E + ++ I+E + EEK+ + E
Sbjct: 274 LQSVSAKLQAQVE-----ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 107 ANKENREAQMAAKLERLREKDKHI---EEVRKNKESK 140
+E +E +M + E + EK++ + EE+ KE K
Sbjct: 329 KIRE-QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 43.5 bits (101), Expect = 7e-05
Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Query: 42 KKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVL-QKAIEENNNFSKMAEEK 100
+++ L E + K+ EE+ + E + +Q E RE EKE+ QK + E + EEK
Sbjct: 259 RQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEK 318
Query: 101 LTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKD 141
+ + E +E +E +M + ERL E++K + E + ++
Sbjct: 319 MWEQEEKMRE-QEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
Score = 38.9 bits (89), Expect = 0.002
Identities = 21/109 (19%), Positives = 58/109 (53%), Gaps = 2/109 (1%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100
++++ + + ++K+ EER + E ++ +Q + R EK + ++ E ++ E+K
Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK 303
Query: 101 LTHKMEANKENREAQMAAKLERLREKDKHI--EEVRKNKESKDPADETE 147
+ E + +E +M + E++RE+++ + +E R ++ K ++ +
Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352
Score = 38.5 bits (88), Expect = 0.002
Identities = 34/149 (22%), Positives = 76/149 (51%), Gaps = 9/149 (6%)
Query: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 60
M + +++ EKR Q EL + KE + L ++++ ++E ++K+ EE+
Sbjct: 271 MREQEEKMRRQEKRLREQEKEL--REQEKELREQKKL---REQEEQMQEQEEKMWEQEEK 325
Query: 61 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAE--EKLTHKMEANKENREAQMAA 118
+ E ++ +Q E EK++ ++ + + +M E E+L K E +E + +M
Sbjct: 326 MREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE--QEKMWE 383
Query: 119 KLERLREKDKHIEEVRKNKESKDPADETE 147
+ E+++E+++ E +K +E ++ E E
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQE 412
Score = 37.4 bits (85), Expect = 0.005
Identities = 37/147 (25%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Query: 4 SDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKS 63
+D ++EL K + EL + + E + KKK+ E+Q+KL AE +
Sbjct: 157 ADRYIEELTKERDALSLELYRNTITNEEL--------KKKNA---ELQEKLRLAESEKSE 205
Query: 64 HEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERL 123
+ V K+L K E K +L + +E+ + E +E +M + ERL
Sbjct: 206 IQLNV-KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERL 264
Query: 124 REKD---KHIEEVRKNKESKDPADETE 147
RE++ + EE + +E + E E
Sbjct: 265 REQEGKMREQEEKMRRQEKRLREQEKE 291
Score = 35.4 bits (80), Expect = 0.018
Identities = 22/108 (20%), Positives = 56/108 (51%), Gaps = 7/108 (6%)
Query: 41 KKKDLSLEEI----QKKLEAAEERRKSHEAEVLKQLAEKREHEK---EVLQKAIEENNNF 93
+KK EE+ ++K++ EE+ + E ++ +Q + +E E+ E +K E+
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Query: 94 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKD 141
+E++ + E + +E +M + E++RE+++ + E + + ++
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673
Score = 34.7 bits (78), Expect = 0.031
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 5/109 (4%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100
+KK EE ++ + +E+ K + K E+R E+E K + E + EEK
Sbjct: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE---KKMREEEEMMREQEEK 582
Query: 101 LTHKMEANKENREA--QMAAKLERLREKDKHIEEVRKNKESKDPADETE 147
+ + E +E E + K++ EK EE +E +D E E
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Score = 34.3 bits (77), Expect = 0.040
Identities = 25/100 (25%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
Query: 49 EIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEAN 108
E ++L EER + E + + Q EK EK+ ++ + + KM EE+ + E
Sbjct: 511 EQDERLREKEERMR--EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
Query: 109 KENREAQMAAKLERLREKDKHI-EEVRKNKESKDPADETE 147
E M + E+++E+++ + E+ K E ++ E E
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608
Score = 33.9 bits (76), Expect = 0.052
Identities = 27/106 (25%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
Query: 40 PKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEE 99
P++K+ E Q+K++ EE+ E ++ Q + +K Q+ + E + EE
Sbjct: 436 PEQKEKLWE--QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 493
Query: 100 KLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADE 145
K+ + E ++E +M + ERLREK++ + E +K + ++ E
Sbjct: 494 KMRDQ-EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
Score = 32.7 bits (73), Expect = 0.12
Identities = 28/126 (22%), Positives = 56/126 (44%), Gaps = 7/126 (5%)
Query: 27 RSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVL--- 83
R +E + +++ +E +KK EE K E E +++ +K E+E++
Sbjct: 522 RMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE--KMREEERMREREKKMREEEEMMREQ 579
Query: 84 QKAIEENNNFSKMAEEKLTHKMEANKENREA--QMAAKLERLREKDKHIEEVRKNKESKD 141
++ ++E + EEK+ + E +E E + K+ E+DK E+ E ++
Sbjct: 580 EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639
Query: 142 PADETE 147
E E
Sbjct: 640 KMQEQE 645
Score = 32.0 bits (71), Expect = 0.20
Identities = 25/108 (23%), Positives = 55/108 (50%), Gaps = 7/108 (6%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100
++++ + E ++K+ EE+ + E ++ +Q + E E+E ++E EEK
Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE---DKMQEQEEMMWEQEEK 640
Query: 101 LTHKMEANKENREAQMAAKLERLREKDKHI---EEVRKNKESKDPADE 145
+ + E E +E +M + E++RE+++ + EE + +E K E
Sbjct: 641 MQEQEEKMWE-QEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
Score = 31.2 bits (69), Expect = 0.34
Identities = 25/102 (24%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Query: 42 KKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKL 101
+++ ++E ++K+ EE+ E E Q E+ E+E + ++E EEK+
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE---EKMQEQEEKMWEQEEKM 655
Query: 102 THKMEANKENREAQMAAKLERLREKDKHI---EEVRKNKESK 140
+ E +E +E +M + E++RE+++ + EE + +E K
Sbjct: 656 REQEEKMRE-QEEKMQGQEEKMREQEEKMQGQEEKMREQEEK 696
Score = 30.4 bits (67), Expect = 0.58
Identities = 24/102 (23%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVL--KQLAEKREHEKEVLQKAIEENNNFSKMAE 98
++++ + E ++K+ EE K E E + +Q + +E E+++ ++ + KM E
Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664
Query: 99 EKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
++ KM+ +E Q K++ EK + EE + +E K
Sbjct: 665 QE--EKMQGQEEKMREQ-EEKMQGQEEKMREQEEKMRGQEEK 703
Score = 30.0 bits (66), Expect = 0.75
Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 9/105 (8%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQ---LAEKREHEKEVLQKAIEENNNFSKMA 97
++++ + E ++K+ E++ E + +Q L EK E +E QK + + KM
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE--QKKMWQQEE--KMR 537
Query: 98 EEKLTHKMEANKENREAQMAAKLE-RLREKD-KHIEEVRKNKESK 140
EEK T + E ++E +M + R REK + EE+ + +E K
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582
Score = 26.6 bits (57), Expect = 8.3
Identities = 23/109 (21%), Positives = 56/109 (51%), Gaps = 11/109 (10%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKM--AE 98
++++ + E ++ + EE+ + E + +Q E++E +++ L + E+ KM E
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQ--EEKEWQQQRLPEQKEKLWEQEKMQEQE 452
Query: 99 EKLTHKMEANKENRE----AQMAAKLERLREKDKHI---EEVRKNKESK 140
EK+ + E ++ E + + E++RE++ + EE +++E K
Sbjct: 453 EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501
>gi|24307965 UBX domain containing 2 [Homo sapiens]
Length = 508
Score = 43.1 bits (100), Expect = 9e-05
Identities = 26/89 (29%), Positives = 49/89 (55%), Gaps = 9/89 (10%)
Query: 39 PPKKKDLSLEEIQKKLEAA-EERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMA 97
P + ++ +E + KKLE EE+RK E +K+ E+R+ KE+L ++ +
Sbjct: 191 PAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEML--------DYKRKQ 242
Query: 98 EEKLTHKMEANKENREAQMAAKLERLREK 126
EE+LT +M + +A+ A ER++++
Sbjct: 243 EEELTKRMLEERNREKAEDRAARERIKQQ 271
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 42.7 bits (99), Expect = 1e-04
Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 11/110 (10%)
Query: 39 PPKKKDLSLEEIQ-KKLEAAEERRKSHEAEVLKQ-------LAEKREHEKEVLQKAIEEN 90
P ++++L EE Q +KLE E RR+ E E +Q L K+E E+ Q+ E
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 91 NNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
+ EE+ ++ +E R Q +L R +E+++ +++R+ +E +
Sbjct: 325 QERREQQEERREQQLRREQEERREQ---QLRREQEEERREQQLRREQEEE 371
Score = 39.3 bits (90), Expect = 0.001
Identities = 27/105 (25%), Positives = 52/105 (49%), Gaps = 9/105 (8%)
Query: 42 KKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKL 101
K+D E ++ L+ EE R+ + +QL ++E +E K EE EE+L
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE--------EERL 528
Query: 102 THKMEANKENREAQMAAKLERL-REKDKHIEEVRKNKESKDPADE 145
++ + ++ R Q + + L RE++K +E+ R+ + K +E
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
Score = 37.4 bits (85), Expect = 0.005
Identities = 20/91 (21%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Query: 48 EEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEA 107
E+ Q++L ++ R+ E E +Q E+RE ++ Q+ EE E++ + +
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ--EERREQQLRREQEERREQQL 351
Query: 108 NKENREAQMAAKLERLREKDKHIEEVRKNKE 138
+E E + +L R +E+++ +++R+ ++
Sbjct: 352 RREQEEERREQQLRREQEEERREQQLRREQQ 382
Score = 37.0 bits (84), Expect = 0.006
Identities = 20/93 (21%), Positives = 46/93 (49%)
Query: 48 EEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEA 107
EE +++ + E++ E E ++ KR+ E+E LQ+ + + EE+ ++
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 108 NKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
+E R Q + RE+++ +++ K +E +
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Score = 34.7 bits (78), Expect = 0.031
Identities = 24/110 (21%), Positives = 52/110 (47%), Gaps = 5/110 (4%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100
+++ L EE Q++ E EE + + E + E++E E++ Q+ + + EE+
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ--QQRLRREQQLRRKQEEE 313
Query: 101 LTHKMEANK---ENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETE 147
+ E + E RE Q + ++LR + + E + +E ++ E +
Sbjct: 314 RREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Score = 34.7 bits (78), Expect = 0.031
Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 3/95 (3%)
Query: 41 KKKDL-SLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEE 99
K++D S EE Q E EE+R+ E + ++ E+ + +E ++ + K EE
Sbjct: 1308 KRRDRKSQEEKQLLREEREEKRRRQETD--RKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 100 KLTHKMEANKENREAQMAAKLERLREKDKHIEEVR 134
+L H+ + K E Q + ER R+ K +++R
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
Score = 34.3 bits (77), Expect = 0.040
Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 12/151 (7%)
Query: 7 QVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEA 66
Q +E ++R +A E L EFP ++ LE +K E +++R+ +
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
Query: 67 EVLKQLAEKREHEKEVLQKAIEENNNFSK-------MAEEKLTHKMEANKENREAQ-MAA 118
V ++ EK ++E + + EE + EE+ K+E + RE Q
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Query: 119 KLERLREKD----KHIEEVRKNKESKDPADE 145
+ +RLR + K EE R+ +E + E
Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEERREQQE 326
Score = 34.3 bits (77), Expect = 0.040
Identities = 32/136 (23%), Positives = 60/136 (44%), Gaps = 7/136 (5%)
Query: 12 EKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQ 71
E+ + +L+ R K E+ KK +L EE ++ L E+R+ E E +Q
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE-EQLLREEREKRRLQERE--RQ 1049
Query: 72 LAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIE 131
E+ E ++E Q EE + E+ K E ++ E + + E+ R +++
Sbjct: 1050 YREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE-- 1107
Query: 132 EVRKNKESKDPADETE 147
R+ +E ++ E E
Sbjct: 1108 --RQCREEEELQQEEE 1121
Score = 33.9 bits (76), Expect = 0.052
Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
Query: 51 QKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKE 110
+++L E RK E E L+Q E+ + ++ + I E EE+ + E +++
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Query: 111 NREAQMAAKLERLREKDKHIEEVRKNKESKDPADETE 147
RE + + ER ++ + E RK +E + E E
Sbjct: 1773 FREEEQ-LRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Score = 33.5 bits (75), Expect = 0.068
Identities = 21/99 (21%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
Query: 51 QKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKE 110
+++ E E+R K E E + KREHE+E ++ + E + A E++ ++ +
Sbjct: 649 REQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE--QEQARERIKSRIPKWQW 706
Query: 111 NREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 149
E++ A+ ++ + + E R+ +E ++ E++
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745
Score = 33.1 bits (74), Expect = 0.089
Identities = 24/117 (20%), Positives = 56/117 (47%), Gaps = 16/117 (13%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKRE-----------HEKEVLQ----- 84
+++ L E +++L + E RK E E L+Q E+++ E+E LQ
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 85 KAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKD 141
+ + + + AEE+ + ++ +E +E + +R +E+++ + E ++ K+
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Score = 32.7 bits (73), Expect = 0.12
Identities = 23/87 (26%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
Query: 58 EERRKSHEAEVLKQLAEKREHEKEVLQKAI----EENNNFSKMAEEKLTHKMEANKENRE 113
EE + HE E KQ KR+ E+E ++ + EE + E++L + E +E R
Sbjct: 461 EEETERHEQERRKQQL-KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL 519
Query: 114 AQMAAKLERLREKDKHIEEVRKNKESK 140
+ + ERL+++ + +++R+ +E +
Sbjct: 520 KRQEEE-ERLQQRLRSEQQLRREQEER 545
Score = 32.7 bits (73), Expect = 0.12
Identities = 27/132 (20%), Positives = 61/132 (46%), Gaps = 4/132 (3%)
Query: 9 KELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEV 68
+E EKR + E L +E + +++ L+ Q+ E E+R K E E
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE--ERLEQRLKREEVER 609
Query: 69 LKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDK 128
L+Q E+R ++ ++ EE +EE+ + + + ++ + +L+R E+++
Sbjct: 610 LEQ--EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Query: 129 HIEEVRKNKESK 140
+ +++ E +
Sbjct: 668 LEQRLKREHEEE 679
Score = 32.3 bits (72), Expect = 0.15
Identities = 31/142 (21%), Positives = 65/142 (45%), Gaps = 13/142 (9%)
Query: 10 ELEKRASGQAFELILSPRSKESV-PEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEV 68
+LE+ + L P +E + E L ++++L EE +K+ E+ R+ E E
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR-RRQEQERQYREEEQ 935
Query: 69 LKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKME---------ANKENREAQMAAK 119
L+Q E+ E+ ++ E + K ++KL K E ++ RE + +
Sbjct: 936 LQQEEEQLLREEREKRRRQERERQYRK--DKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
Query: 120 LERLREKDKHIEEVRKNKESKD 141
E +E+++ + E R+ + ++
Sbjct: 994 EELQQEEEQLLREEREKRRRQE 1015
Score = 32.0 bits (71), Expect = 0.20
Identities = 23/100 (23%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100
+++ L ++ +++ E EERR+ E +Q E+RE + Q+ E + EE+
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERR--EQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 101 LTHKM--EANKENREAQMAAKLERLREKDKHIEEVRKNKE 138
++ E +E RE Q+ + + RE+ E+ + ++
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399
Score = 31.2 bits (69), Expect = 0.34
Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 48 EEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNN--FSKMAEEKLTHKM 105
EE +++L EE ++ + ++L ++E ++ L K EE + EE+L ++
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602
Query: 106 EANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADE 145
+ + R Q + +RL+ ++ EE R+ + K E
Sbjct: 603 KREEVERLEQEERREQRLKREEP--EEERRQQLLKSEEQE 640
Score = 30.8 bits (68), Expect = 0.44
Identities = 21/94 (22%), Positives = 49/94 (52%), Gaps = 3/94 (3%)
Query: 49 EIQKKLEAAEER-RKSHEAEVLKQ-LAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKME 106
E Q + E EER + HE E +Q L ++E ++ L++ E + + +++L E
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 107 ANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
+ R ++ + ER ++++ +++R+ +E +
Sbjct: 482 EERRERWLKLEEE-ERREQQERREQQLRREQEER 514
Score = 30.8 bits (68), Expect = 0.44
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 13/139 (9%)
Query: 12 EKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQ 71
E++ + +L+ R K E K K L +E Q E E+RR+ Q
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR--------Q 984
Query: 72 LAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKME---ANKENREAQMAAKLERLREKDK 128
EK+ E+E LQ+ EE + E++ + E K+ + + L REK +
Sbjct: 985 EREKKYREEEELQQ--EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR 1042
Query: 129 HIEEVRKNKESKDPADETE 147
E R+ +E ++ E E
Sbjct: 1043 LQERERQYREEEELQQEEE 1061
Score = 30.4 bits (67), Expect = 0.58
Identities = 20/115 (17%), Positives = 56/115 (48%), Gaps = 17/115 (14%)
Query: 48 EEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKE-------------VLQKAIEENNNFS 94
++++++ + E++ E ++ ++ +RE E+E L++ EE ++
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458
Query: 95 KMAEEKLTHKMEANKE----NREAQMAAKLERLREKDKHIEEVRKNKESKDPADE 145
K EE H+ E K+ ++E + + +L E+++ ++ R+ ++ + +E
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
Score = 30.4 bits (67), Expect = 0.58
Identities = 20/106 (18%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREH---EKEVLQKAIEENNNFSKMA 97
++++ L+E Q++ + E+RR L++ ++R H K LQ+ + + +
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 98 EEKL--THKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKD 141
EE+L + + ++ +E Q + + +E+++ + E R+ + ++
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
Score = 30.0 bits (66), Expect = 0.75
Identities = 22/102 (21%), Positives = 51/102 (50%), Gaps = 4/102 (3%)
Query: 41 KKKDLSLEEIQKKLE--AAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAE 98
+++ L +E +++L+ E++ E E ++ KRE EK + Q+ E+ + E
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ--RLKREQE 572
Query: 99 EKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
E+ ++ +E R+ ++ + E E+ EEV + ++ +
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEE 614
Score = 29.6 bits (65), Expect = 0.98
Identities = 29/136 (21%), Positives = 60/136 (44%), Gaps = 6/136 (4%)
Query: 7 QVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAE-ERRKSHE 65
Q + E+R Q E L R + +++ L E +K+LE E+R E
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 66 AEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLRE 125
E + KRE E+ + E+ + + + ++E +E RE +L+R
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLE-QEERRE----QRLKREEP 625
Query: 126 KDKHIEEVRKNKESKD 141
+++ +++ K++E ++
Sbjct: 626 EEERRQQLLKSEEQEE 641
Score = 29.6 bits (65), Expect = 0.98
Identities = 27/146 (18%), Positives = 57/146 (39%), Gaps = 6/146 (4%)
Query: 10 ELEKRASGQAFELILSPRSKESVPEFPLSPPKKK----DLSLEEIQKKLEAAEERRKSHE 65
+LE A + ++ PR +E K++ +L +E ++ +E + +
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
Query: 66 AEVLKQLAEKREHEKEVL--QKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERL 123
Q EK E ++ L + + E AEE+ + E E + + R
Sbjct: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
Query: 124 REKDKHIEEVRKNKESKDPADETEAD 149
REK+ E + + ++ A + + +
Sbjct: 827 REKELQFLEEEEQLQRRERAQQLQEE 852
Score = 29.3 bits (64), Expect = 1.3
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 13/137 (9%)
Query: 12 EKRASGQAFELILSPRSKESVPE-----FPLSPPKKKDLSLEEI---QKKLEAAEERRKS 63
E+R + EL R +E V + P K++ LE +++L+ EE+
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 64 HEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERL 123
E E +Q E++ E+E LQ+ + + L + E KEN A + ++
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKEN-----AVRDNKV 1240
Query: 124 REKDKHIEEVRKNKESK 140
K + E+ R+ ++S+
Sbjct: 1241 YCKGRENEQFRQLEDSQ 1257
Score = 29.3 bits (64), Expect = 1.3
Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKRE-HEKEVLQKAIEENNNFSKMAEE 99
+++ L E +++L E RK E E L+Q E+++ +E +K EE + E+
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 100 KLTHKMEANK---ENREAQMAAKLERLREK 126
+L + K E + Q+ + +RLR++
Sbjct: 1811 QLRPQQRDGKYRWEEEQLQLEEQEQRLRQE 1840
Score = 28.9 bits (63), Expect = 1.7
Identities = 22/107 (20%), Positives = 51/107 (47%), Gaps = 4/107 (3%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100
++K L E+ ++ E ++RR+ + + ++ E+ E+E Q + +E + ++ E+K
Sbjct: 1530 QRKFLQEEQQLRRQERGQQRRQDRDRKFREE--EQLRQEREEQQLSRQERDRKFRLEEQK 1587
Query: 101 LTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETE 147
+ + + K + Q + E ++ E RK +E + E E
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQE--GQQQLRQERDRKFREDEQLLQERE 1632
Score = 28.5 bits (62), Expect = 2.2
Identities = 18/105 (17%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100
++++ L Q++ + RR+ E +QL +RE E+E ++ + + + +
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQL--RREQEEERREQQLRREQQLRREQQLR 390
Query: 101 LTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADE 145
++ ++ R Q + ++LR + + E + +E ++ E
Sbjct: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435
Score = 28.5 bits (62), Expect = 2.2
Identities = 21/111 (18%), Positives = 47/111 (42%), Gaps = 10/111 (9%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAE----------KREHEKEVLQKAIEEN 90
+++ L E+ ++ + E + HE E +Q + KRE E E ++ +
Sbjct: 415 REQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQ 474
Query: 91 NNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKD 141
EE+ ++ +E R Q + ++LR + + E R ++ ++
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Score = 28.1 bits (61), Expect = 2.9
Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 7/107 (6%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100
K+++L EE ++ L E+R+ E E +Q E+ E ++E Q EE + E+
Sbjct: 1082 KEEELQQEE-EQLLREEPEKRRRQERE--RQCREEEELQQEEEQLLREEREKRRRQELER 1138
Query: 101 LTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETE 147
++ E + E Q+ L EK + E R+ +E ++ E E
Sbjct: 1139 -QYREEEEVQQEEEQL---LREEPEKRRRQELERQYREEEELQQEEE 1181
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 42.4 bits (98), Expect = 1e-04
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 8/103 (7%)
Query: 47 LEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKME 106
L+E++K+ + E + E E ++ E RE E+E EE K E++ K +
Sbjct: 2234 LDELEKQESLSSEEEEEREEEEEREEEEVREEEEE----RKEEEEGEEKQVEKEEEEKKK 2289
Query: 107 ANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 149
KE ++ ++ K E EK EE+ +E++ +DE E +
Sbjct: 2290 KKKEKKKEEVQEKEEVFEEK----EEIMSEEETESLSDEEEEE 2328
Score = 37.4 bits (85), Expect = 0.005
Identities = 31/160 (19%), Positives = 69/160 (43%), Gaps = 20/160 (12%)
Query: 1 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSP-----------PKKKDLSLEE 49
M + + ++ E E + + + E+IL + + E + P K+ D E+
Sbjct: 2153 MINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEK 2212
Query: 50 IQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANK 109
+++ E + H +E ++ L ++ E ++ + + EE + EE++ + E K
Sbjct: 2213 FSSQVDEVES--EEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERK 2270
Query: 110 ENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 149
E E + ++ +K EE +K K+ K + E +
Sbjct: 2271 EEEEGEE-------KQVEKEEEEKKKKKKEKKKEEVQEKE 2303
Score = 35.8 bits (81), Expect = 0.014
Identities = 35/143 (24%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Query: 3 SSDIQVKELEKRASGQAFELILSPRSKESVP-EFPLSPPKKKDLSLEEIQKKLEAAEERR 61
SS + E E+ S + L+ +ES+ E ++++ EE++++ E +E
Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273
Query: 62 KSHEAEVLKQLAEKR----EHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMA 117
+ E +V K+ EK+ E +KE +Q E+ F + E + E+ + E + +
Sbjct: 2274 EGEEKQVEKEEEEKKKKKKEKKKEEVQ---EKEEVFEEKEEIMSEEETESLSDEEEEEES 2330
Query: 118 AKLERLREKDKHIEEVRKNKESK 140
LE E D+ E ++K K+ K
Sbjct: 2331 CSLE--EEVDREKEILKKEKQFK 2351
Score = 33.9 bits (76), Expect = 0.052
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 21/93 (22%)
Query: 59 ERRKSHEAEVLKQLAEKREHEKEVLQ----------KAIEENNNFSKMA------EEKLT 102
E+R E E L Q EK E+E+LQ K + EN SK EE++T
Sbjct: 1486 EKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVT 1545
Query: 103 HKMEANKENREAQMAAKLERLREKDKHIEEVRK 135
+ E ++E E K +++ E+ +HI+E K
Sbjct: 1546 LEEEVSREGEE-----KEQQVTEEQRHIQEEHK 1573
Score = 32.7 bits (73), Expect = 0.12
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEV-LQKAIEENNNFSKMAEE 99
KKK+ EE+Q+K E EE+ + E + L+++ E E+ L++ ++ K ++
Sbjct: 2290 KKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQ 2349
Query: 100 -KLTHKMEANKENRE 113
KL + + RE
Sbjct: 2350 FKLQEQRRKSLRGRE 2364
Score = 32.0 bits (71), Expect = 0.20
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 9 KELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEV 68
K+L+ Q +E +LS +SKE + ++++S E +K+ + EE+R E
Sbjct: 1514 KKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHK 1573
Query: 69 LKQLAEKREH-EKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 120
++ KR EK+ Q+ + K+A+E+ + A +E + AQ K+
Sbjct: 1574 WARIHRKRARAEKKRAQEERKLAQEEEKLAQEE---RQLAQEERKLAQAYVKI 1623
Score = 31.6 bits (70), Expect = 0.26
Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 8/128 (6%)
Query: 12 EKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQ 71
EK+ + E + R K S E L+ ++++L ++E +K A+ + K E E ++
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLA--QEEELLIQEKEK---LAQHKEKMPEEE--ER 1797
Query: 72 LAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREK-DKHI 130
L KRE E K ++ + EE +KM ++ AQ L + +EK +
Sbjct: 1798 LGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRK 1857
Query: 131 EEVRKNKE 138
E + NKE
Sbjct: 1858 ENLLYNKE 1865
Score = 29.6 bits (65), Expect = 0.98
Identities = 29/129 (22%), Positives = 56/129 (43%), Gaps = 3/129 (2%)
Query: 12 EKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQ 71
EK Q E +L + + + + L K K L K L EE+ + V+K+
Sbjct: 1849 EKEKLAQRKENLLYNKERLTHSKKQLVQVKNK---LGMFNKILAQVEEKLTQEKETVIKK 1905
Query: 72 LAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIE 131
+ E EK+++Q K+A+EK+ +E + ++ +L+ +E+
Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNL 1965
Query: 132 EVRKNKESK 140
E+++ E K
Sbjct: 1966 EMKRLAEEK 1974
Score = 28.9 bits (63), Expect = 1.7
Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Query: 10 ELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEE-RRKSHEAEV 68
ELEK+ S + E +E E +++ E +K++E EE ++K + +
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Query: 69 LKQLAEKRE--HEKEVLQKAIEENNNFSKMAEEK----LTHKMEANKENREAQMAAKLER 122
+++ EK E EKE + EE + S EE+ L +++ KE + + KL+
Sbjct: 2296 KEEVQEKEEVFEEKEEIMSE-EETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQE 2354
Query: 123 LREK 126
R K
Sbjct: 2355 QRRK 2358
Score = 26.9 bits (58), Expect = 6.4
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
Query: 51 QKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKME--AN 108
++KL EE+ E +QLA++ + K +++ ++ AE K K E A
Sbjct: 1592 ERKLAQEEEKLAQEE----RQLAQEERKLAQAYVKITQDDREMAQ-AEGKFAQKEETLAQ 1646
Query: 109 KENREAQMAAKLERLREK-DKHIEEVRKNKE 138
+ + +Q A KL + R+K K E+V + +E
Sbjct: 1647 RGEKLSQEAEKLAQKRKKLAKKWEKVAREEE 1677
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 42.4 bits (98), Expect = 1e-04
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEK----------REHEKEVLQKAIEEN 90
KK++ E +K+ E ++R++ E E K+ EK RE +K+ +K E
Sbjct: 67 KKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERE 126
Query: 91 NNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
N + + K K + KE + + K ER R+K K E +K + ++
Sbjct: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR 176
Score = 40.8 bits (94), Expect = 4e-04
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 3/112 (2%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKS---HEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMA 97
++K E +KK E E R++ E + K+ +KR E++ ++ + K
Sbjct: 105 ERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRK 164
Query: 98 EEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 149
+E+ K E N++ R+ + K R R+K++ E +K + KD + + D
Sbjct: 165 KEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTD 216
Score = 40.4 bits (93), Expect = 6e-04
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Query: 8 VKELEKRASGQA-FELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEA 66
VK + RA+ + EL + S S P +KK+ E +K+ E +R+ +
Sbjct: 2 VKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKK 61
Query: 67 EVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREK 126
E K+ +R E+E +K E+ K EK K + K+ RE + + ER ++K
Sbjct: 62 EKKKRKKRERGKERERKRKEREKQR---KERREKERRKRKKEKKKRERKQRGRRERKKKK 118
Query: 127 DKHIEEVRKNKESKD 141
++ E R+NK+ ++
Sbjct: 119 ERK-ERERENKQRRE 132
Score = 34.7 bits (78), Expect = 0.031
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Query: 51 QKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKE 110
Q++ E +ERR+ + + ++ KRE K+ +K + K E K + + KE
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKK--EKKKRKKRERGKERERKRKEREKQRKE 88
Query: 111 NREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 149
RE + + +R +EK K + R +E K + E +
Sbjct: 89 RREKE---RRKRKKEKKKRERKQRGRRERKKKKERKERE 124
Score = 34.7 bits (78), Expect = 0.031
Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 4/97 (4%)
Query: 42 KKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKL 101
KK+ + +++ + E +RK E KQ E+RE E+ +K ++ + E+
Sbjct: 60 KKEKKKRKKRERGKERERKRKERE----KQRKERREKERRKRKKEKKKRERKQRGRRERK 115
Query: 102 THKMEANKENREAQMAAKLERLREKDKHIEEVRKNKE 138
K +E Q + + R K K +E ++ KE
Sbjct: 116 KKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
Score = 33.9 bits (76), Expect = 0.052
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
Query: 49 EIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEAN 108
E ++K E ++ +K + + E++ E+E +K E + E+K + +
Sbjct: 51 EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110
Query: 109 KENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 149
+ R+ + K ER RE + E RK + K E + +
Sbjct: 111 RRERKKKKERK-ERERENKQRRERKRKKRRKKKRRKERKRE 150
Score = 31.6 bits (70), Expect = 0.26
Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 4/120 (3%)
Query: 25 SPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKR---EHEKE 81
S R KE ++K+ E +K+ + ++R + E E ++ EK+ EKE
Sbjct: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
Query: 82 VLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKD 141
++ E+ K + K + KE RE + + ER R+K + + ++ K K+
Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKE-RERENKQRRERKRKKRRKKKRRKERKREKE 152
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 42.4 bits (98), Expect = 1e-04
Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 7/102 (6%)
Query: 48 EEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQ---KAIEENN-NFSKMAEEKLTH 103
E+ QK+LE A+ + + E+ ++ E+ E EKE L K IEE K EE+
Sbjct: 312 EKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRK 371
Query: 104 KMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADE 145
+E ++E + A+ A ERL EK++ E K+ +K AD+
Sbjct: 372 ALELDQERKRAKEEA--ERL-EKERRAAEEAKSAIAKQAADQ 410
Score = 37.0 bits (84), Expect = 0.006
Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 14/114 (12%)
Query: 41 KKKDLSLEE---IQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQ------KAIEENN 91
KK++++ +E I+++ E ER K E + +K E E ++ L+ +A EE
Sbjct: 328 KKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAE 387
Query: 92 NFSK---MAEEKLTH--KMEANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
K AEE + K A++ + Q+AA+L K +EE +K KE +
Sbjct: 388 RLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEE 441
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 42.0 bits (97), Expect = 2e-04
Identities = 37/152 (24%), Positives = 73/152 (48%), Gaps = 25/152 (16%)
Query: 7 QVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLE--EIQKKLEAAEE----- 59
Q+K+LE A L + ++++ + DL L E+ K+LE +E
Sbjct: 731 QIKKLE------ADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSST 784
Query: 60 ----RRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEAN------- 108
++KS E +KQ K+E EK++L++ E + +K+ E+L ++++
Sbjct: 785 RLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKV 844
Query: 109 KENREAQMAAKLERLREKDKHIEEVRKNKESK 140
K +EA M +L +++K + + KN +S+
Sbjct: 845 KMEKEALM-TELSTVKDKLSKVSDSLKNSKSE 875
Score = 32.7 bits (73), Expect = 0.12
Identities = 24/115 (20%), Positives = 55/115 (47%), Gaps = 19/115 (16%)
Query: 42 KKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKL 101
KK+ L+E K L+ ++ + E K+L ++ E+ + + +K+ EE
Sbjct: 1093 KKEQQLQERCKALQDIQKEKSLKE----KELVNEKSKLAEIEEIKCRQEKEITKLNEELK 1148
Query: 102 THKMEANKE------------NREAQMAAKLERLR---EKDKHIEEVRKNKESKD 141
+HK+E+ KE ++ ++ K + L+ E++K +++ K++ K+
Sbjct: 1149 SHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKE 1203
Score = 28.1 bits (61), Expect = 2.9
Identities = 35/144 (24%), Positives = 63/144 (43%), Gaps = 16/144 (11%)
Query: 4 SDIQVKELEKRASGQAFELI------LSPRSKESVPEFPLSPPKKKD--LSLEEIQKKLE 55
+++Q ++EK A + +S K S EF K K L LE+ K+L+
Sbjct: 839 TELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELK 898
Query: 56 AAEERRKSHEAEVLKQLAEKREHEKEVL-QKAIEENNNFSKMAEEKLTHKMEANKENREA 114
+ + + + K+L + E EKE Q +E N+ ++ + + T K E E
Sbjct: 899 HQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLK---QNEKEEQ 955
Query: 115 QMAAKLERLR----EKDKHIEEVR 134
Q+ + L+ +K K IE ++
Sbjct: 956 QLQGNINELKQSSEQKKKQIEALQ 979
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 42.0 bits (97), Expect = 2e-04
Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 38 SPPKKKD----LSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF 93
S K+KD + +E K+ + +ER + E E K+ + ++ +KE +K E++
Sbjct: 373 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE-REKDREKDKEK 431
Query: 94 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVR-KNKESKDP 142
+ E + H+ + +KE + Q K ER +++ K I+E R K+K+S+ P
Sbjct: 432 DREREREKEHEKDRDKEKEKEQDKEK-EREKDRSKEIDEKRKKDKKSRTP 480
Score = 40.0 bits (92), Expect = 7e-04
Identities = 28/127 (22%), Positives = 61/127 (48%), Gaps = 6/127 (4%)
Query: 27 RSKESVPEFPLSPPKKKDLSLEEIQKKLEA------AEERRKSHEAEVLKQLAEKREHEK 80
RS++ SP KK+ S E + + + + R K E E +K+ ++E E+
Sbjct: 342 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 401
Query: 81 EVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
E ++ +E +E+ + + +++RE + + E+ R+K+K E+ ++ + K
Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 461
Query: 141 DPADETE 147
D + E +
Sbjct: 462 DRSKEID 468
Score = 33.1 bits (74), Expect = 0.089
Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 17/126 (13%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKRE---HEKEVLQKAIEENNNFS--- 94
K + S ++K ++ R +SH +Q +R H+K + ++ + S
Sbjct: 315 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSR 374
Query: 95 ---KMAEEKLTHKMEANKENREAQMAAKLERLREK--------DKHIEEVRKNKESKDPA 143
K EK+ K +++RE + + ER +EK DK E+ R+ + KD
Sbjct: 375 DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 434
Query: 144 DETEAD 149
E E +
Sbjct: 435 REREKE 440
Score = 32.3 bits (72), Expect = 0.15
Identities = 29/124 (23%), Positives = 49/124 (39%), Gaps = 7/124 (5%)
Query: 27 RSKESVPEFPLSPPKKKDLSLE---EIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVL 83
R KE E K +D E E K+ + ER K HE + K+ ++++ EKE
Sbjct: 401 REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE 460
Query: 84 QKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDK----HIEEVRKNKES 139
+ +E + K ++ T N R + + R R + + K K S
Sbjct: 461 KDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSS 520
Query: 140 KDPA 143
+ P+
Sbjct: 521 RSPS 524
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 42.0 bits (97), Expect = 2e-04
Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 38 SPPKKKD----LSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF 93
S K+KD + +E K+ + +ER + E E K+ + ++ +KE +K E++
Sbjct: 257 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE-REKDREKDKEK 315
Query: 94 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVR-KNKESKDP 142
+ E + H+ + +KE + Q K ER +++ K I+E R K+K+S+ P
Sbjct: 316 DREREREKEHEKDRDKEKEKEQDKEK-EREKDRSKEIDEKRKKDKKSRTP 364
Score = 40.0 bits (92), Expect = 7e-04
Identities = 28/127 (22%), Positives = 61/127 (48%), Gaps = 6/127 (4%)
Query: 27 RSKESVPEFPLSPPKKKDLSLEEIQKKLEA------AEERRKSHEAEVLKQLAEKREHEK 80
RS++ SP KK+ S E + + + + R K E E +K+ ++E E+
Sbjct: 226 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 285
Query: 81 EVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
E ++ +E +E+ + + +++RE + + E+ R+K+K E+ ++ + K
Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 345
Query: 141 DPADETE 147
D + E +
Sbjct: 346 DRSKEID 352
Score = 33.1 bits (74), Expect = 0.089
Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 17/126 (13%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKRE---HEKEVLQKAIEENNNFS--- 94
K + S ++K ++ R +SH +Q +R H+K + ++ + S
Sbjct: 199 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSR 258
Query: 95 ---KMAEEKLTHKMEANKENREAQMAAKLERLREK--------DKHIEEVRKNKESKDPA 143
K EK+ K +++RE + + ER +EK DK E+ R+ + KD
Sbjct: 259 DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 318
Query: 144 DETEAD 149
E E +
Sbjct: 319 REREKE 324
Score = 32.3 bits (72), Expect = 0.15
Identities = 29/124 (23%), Positives = 49/124 (39%), Gaps = 7/124 (5%)
Query: 27 RSKESVPEFPLSPPKKKDLSLE---EIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVL 83
R KE E K +D E E K+ + ER K HE + K+ ++++ EKE
Sbjct: 285 REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE 344
Query: 84 QKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDK----HIEEVRKNKES 139
+ +E + K ++ T N R + + R R + + K K S
Sbjct: 345 KDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSS 404
Query: 140 KDPA 143
+ P+
Sbjct: 405 RSPS 408
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 41.6 bits (96), Expect = 2e-04
Identities = 21/100 (21%), Positives = 54/100 (54%), Gaps = 2/100 (2%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100
++++ + E ++K+ EE K HE E +++ EKR+ E+++ ++ + +E+
Sbjct: 380 RRQEEMMWEKEEKIRELEE--KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 437
Query: 101 LTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESK 140
+ E +E +M + E++ E++K EE ++ ++ +
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE 477
Score = 38.9 bits (89), Expect = 0.002
Identities = 27/111 (24%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAE-- 98
++++ +E ++K+ EE+ + E ++ +Q + RE E+++ ++ KM E
Sbjct: 594 REQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE 653
Query: 99 EKLTHKMEANKENREAQMAAKLERLREKDKHI----EEVRKNKESKDPADE 145
EK+ + E +E E M + E++RE++K I E++R+ +E +E
Sbjct: 654 EKMCEQEEKMQEQEET-MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 703
Score = 38.5 bits (88), Expect = 0.002
Identities = 27/103 (26%), Positives = 56/103 (54%), Gaps = 4/103 (3%)
Query: 48 EEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVL--QKAIEENNNFSKMAEEKLTHKM 105
E+I+++ E E K HE E + + +++E E ++ ++ I E EEK+ +
Sbjct: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKI-REQ 596
Query: 106 EANKENREAQMAAKLERLREKDKHI-EEVRKNKESKDPADETE 147
E ++ +E +M + E++RE+++ I E+ K +E ++ E E
Sbjct: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE 639
Score = 35.0 bits (79), Expect = 0.023
Identities = 25/88 (28%), Positives = 50/88 (56%), Gaps = 6/88 (6%)
Query: 58 EERRKSHEAEVLKQLAEKREHEKEVL--QKAIEENNNFSKMAEEKLTHKMEANKENREAQ 115
EE+R+ E ++ +Q + RE E++V ++ I E + EEK+ + E +E E +
Sbjct: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE-K 620
Query: 116 MAAKLERLREKDKHI---EEVRKNKESK 140
+ + E++RE+++ I EE+ + +E K
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQEQEEK 648
Score = 34.3 bits (77), Expect = 0.040
Identities = 22/107 (20%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Query: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEV--LQKAIEENNNFSKMAE 98
++++ + E ++K+ EE+ + E + +Q + RE EK++ ++ I E + E
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQE 702
Query: 99 EKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADE 145
EK+ + E E E + + R+++K E+ + ++ ++ E
Sbjct: 703 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 33.5 bits (75), Expect = 0.068
Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 10/103 (9%)
Query: 51 QKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAE--------EKLT 102
Q+K+ EE+R+ E E +++ +++E E ++ ++ + K+ E E+
Sbjct: 403 QEKIREQEEKRQ--EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 460
Query: 103 HKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADE 145
H+ E +E + Q ++ R EK EE+ + KE +E
Sbjct: 461 HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE 503
Score = 29.6 bits (65), Expect = 0.98
Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
Query: 58 EERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEA---NKENREA 114
E+ K E E E++ E+E + + E+ + K+ EE+ + E +E +
Sbjct: 521 EQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580
Query: 115 QMAAKLERLREKDKHIEEVRKNKESK 140
+ K+ R EK + EE R+ +E K
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEK 606
Score = 27.3 bits (59), Expect = 4.9
Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 9/99 (9%)
Query: 47 LEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQK---AIEENNNFSKMAEEKLTH 103
L+ + KL+A E + + +Q EK ++E +Q+ I+E + EEK+
Sbjct: 274 LQSVSAKLQAQVEENELWN-RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR- 331
Query: 104 KMEANKENREAQMAAKLERLREKDKHI----EEVRKNKE 138
+ E +E M K E++R +++ + E++R+ +E
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 370
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.119 0.298
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,363,141
Number of Sequences: 37866
Number of extensions: 239262
Number of successful extensions: 5631
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 525
Number of HSP's successfully gapped in prelim test: 724
Number of HSP's that attempted gapping in prelim test: 2218
Number of HSP's gapped (non-prelim): 3224
length of query: 149
length of database: 18,247,518
effective HSP length: 93
effective length of query: 56
effective length of database: 14,725,980
effective search space: 824654880
effective search space used: 824654880
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.