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Search of human proteins with 44888835
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
(1300 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 2603 0.0
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 1067 0.0
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 922 0.0
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 922 0.0
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 693 0.0
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 663 0.0
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 659 0.0
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 535 e-151
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 535 e-151
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 524 e-148
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 517 e-146
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 517 e-146
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 348 2e-95
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 338 2e-92
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 337 6e-92
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 335 2e-91
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 330 4e-90
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 301 2e-81
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 91 9e-18
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 91 9e-18
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 88 6e-17
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 88 6e-17
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 82 4e-15
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 82 4e-15
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 72 3e-12
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 72 3e-12
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 56 3e-07
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 56 3e-07
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 56 3e-07
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 56 3e-07
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 2603 bits (6746), Expect = 0.0
Identities = 1300/1300 (100%), Positives = 1300/1300 (100%)
Query: 1 MGTGPAQTPRSTRAGPEPSPAPPGPGDTGDSDVTQEGSGPAGIRGGETVIRAGMGDSPGR 60
MGTGPAQTPRSTRAGPEPSPAPPGPGDTGDSDVTQEGSGPAGIRGGETVIRAGMGDSPGR
Sbjct: 1 MGTGPAQTPRSTRAGPEPSPAPPGPGDTGDSDVTQEGSGPAGIRGGETVIRAGMGDSPGR 60
Query: 61 GAPERRHKAQPGRARKYEWRPEGPTSMGSLGQREDLQDEDRNSAFTWKVQANNRAYNGQF 120
GAPERRHKAQPGRARKYEWRPEGPTSMGSLGQREDLQDEDRNSAFTWKVQANNRAYNGQF
Sbjct: 61 GAPERRHKAQPGRARKYEWRPEGPTSMGSLGQREDLQDEDRNSAFTWKVQANNRAYNGQF 120
Query: 121 KEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTL 180
KEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTL
Sbjct: 121 KEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTL 180
Query: 181 PWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDV 240
PWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDV
Sbjct: 181 PWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDV 240
Query: 241 VCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASF 300
VCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASF
Sbjct: 241 VCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASF 300
Query: 301 QGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKI 360
QGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKI
Sbjct: 301 QGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKI 360
Query: 361 MKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGS 420
MKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGS
Sbjct: 361 MKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGS 420
Query: 421 SVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARST 480
SVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARST
Sbjct: 421 SVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARST 480
Query: 481 SLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADG 540
SLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADG
Sbjct: 481 SLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADG 540
Query: 541 KLLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALV 600
KLLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALV
Sbjct: 541 KLLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALV 600
Query: 601 TAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTK 660
TAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTK
Sbjct: 601 TAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTK 660
Query: 661 GADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLL 720
GADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLL
Sbjct: 661 GADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLL 720
Query: 721 LQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELL 780
LQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELL
Sbjct: 721 LQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELL 780
Query: 781 SENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALVINGDFLDKLLVSLRKEPRAL 840
SENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALVINGDFLDKLLVSLRKEPRAL
Sbjct: 781 SENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALVINGDFLDKLLVSLRKEPRAL 840
Query: 841 AQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFV 900
AQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFV
Sbjct: 841 AQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFV 900
Query: 901 DLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTADVGVGLAGQE 960
DLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTADVGVGLAGQE
Sbjct: 901 DLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTADVGVGLAGQE 960
Query: 961 GMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGF 1020
GMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGF
Sbjct: 961 GMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGF 1020
Query: 1021 TGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFV 1080
TGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFV
Sbjct: 1021 TGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFV 1080
Query: 1081 QAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSFAVVVALSCLLSITMEVILIIKYWT 1140
QAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSFAVVVALSCLLSITMEVILIIKYWT
Sbjct: 1081 QAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSFAVVVALSCLLSITMEVILIIKYWT 1140
Query: 1141 ALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSIN 1200
ALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSIN
Sbjct: 1141 ALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSIN 1200
Query: 1201 TFPVLALRVIFPALKELRAKEEKVEEGPSEEIFTMEPLPHVHRESRARRSSYAFSHREGY 1260
TFPVLALRVIFPALKELRAKEEKVEEGPSEEIFTMEPLPHVHRESRARRSSYAFSHREGY
Sbjct: 1201 TFPVLALRVIFPALKELRAKEEKVEEGPSEEIFTMEPLPHVHRESRARRSSYAFSHREGY 1260
Query: 1261 ANLITQGTILRRGPGVSSDIASESLDPSDEEAASSPKESQ 1300
ANLITQGTILRRGPGVSSDIASESLDPSDEEAASSPKESQ
Sbjct: 1261 ANLITQGTILRRGPGVSSDIASESLDPSDEEAASSPKESQ 1300
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 1067 bits (2760), Expect = 0.0
Identities = 563/1209 (46%), Positives = 793/1209 (65%), Gaps = 84/1209 (6%)
Query: 106 TWKVQANNRAYNGQ--FKEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNL 163
TW+V+AN+R Y+ Q F LC + KY N I+T KYN ++F+P+NL+EQF R +NL
Sbjct: 63 TWQVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANL 122
Query: 164 FFLIIIILQSIPDISTLPWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILM 223
+FL ++ILQ++P ISTL W++ P++ +L + A +DLVDD+ RHK D+ INNR C+++
Sbjct: 123 YFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIK 182
Query: 224 GKSFKQKKWQDLCVGDVVCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQA 283
FK KW+++ VGDV+ L+K++ VPAD+LLL+S+EP+SLCYVET ++DGETNLKF+ +
Sbjct: 183 DGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMS 242
Query: 284 LMVTHKELATIKKMASFQGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRN 343
L +T + L +A+F G + CE PN+R+ F G L W + + LD +LLRGC IRN
Sbjct: 243 LEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVIRN 302
Query: 344 TDTCYGLVIYAGFDTKIMKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFS 403
TD C+GLVI+AG DTKIMKN GK KRTK+D LMN +V IF+ ++L+ LA G +
Sbjct: 303 TDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYW 362
Query: 404 VKEFKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWD 463
+ + +YL + + F +FW ++I+L+ +P+S+++ E I LG S FI+WD
Sbjct: 363 EAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWD 422
Query: 464 VQMYYKPQDVPAKARSTSLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEA 523
+QMYY +D PAKAR+T+LN+ LGQ+ YIFSDKTGTLTQNI+TF KCCI+G++YG +A
Sbjct: 423 LQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDA 482
Query: 524 T----TRPKENPYLWNKFADGKLLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRES 579
+ + ++ + WN +ADGKL F++ L+ +++ + VR+F+ LLA+CHTVMV
Sbjct: 483 SQHNHNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMV--- 539
Query: 580 PRERPD-QLLYQAASPDEGALVTAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIMDFN 638
+R D QL YQAASPDEGALV AARNFG+ FL+RTQ+T+TI ELG ER Y VLAI+DFN
Sbjct: 540 --DRTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFN 597
Query: 639 STRKRMSVLVRKPEGAICLYTKGADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLA 698
S RKRMS++VR PEG I LY KGADTVI+ERLHR + T++AL FA ETLRTLCL
Sbjct: 598 SDRKRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLC 657
Query: 699 YREVAEDIYEDWQQRHQEASLLLQNRAQALQQ----------LLGATAIEDRLQDGVPET 748
Y+E+ E + +W ++ AS+ NR +AL + LLGATAIED+LQDGVPET
Sbjct: 658 YKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPET 717
Query: 749 IKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENSNNL-- 806
I L K++IKIWVLTGDK+ETA NIGFACELL+E+ I ++I+ +L EN N
Sbjct: 718 ISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGG 777
Query: 807 -------LTRESLSQV--KLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSR 857
+ES AL+I G +L+++L+ +K R + +E
Sbjct: 778 VYAKFAPPVQESFFPPGGNRALIITGSWLNEILLE-KKTKRNKILKLKFPRTEEE----- 831
Query: 858 RDFLYARRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPK 917
RR+ Q R + + +++ FVDLA +C AVICCRVTPK
Sbjct: 832 ------RRMR--------------TQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPK 871
Query: 918 QKALIVALVKKYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCF 977
QKA++V LVK+Y + +TLAIGDGAND+NMIKTA +GVG++GQEGMQAV +SD+ QF +
Sbjct: 872 QKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRY 931
Query: 978 LQRLLLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLL 1037
LQRLLLVHGRWSY+R+CKFLRYFFYK+ A +V W++ +NG++ Q YE WF+ L+N+L
Sbjct: 932 LQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVL 991
Query: 1038 YSTLPVLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMT 1097
Y++LPVL +GL +QDVS + SL P LY+VGQ+D LFNY F ++ HGV TS++ FF+
Sbjct: 992 YTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIP 1051
Query: 1098 LWISRDTAGP--ASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYA 1155
L T G + SD+QSFAV +A + ++++ ++ L YWT + +I S+ Y
Sbjct: 1052 LGAYLQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYF 1111
Query: 1156 IMTTTTQSFWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLALR----VIF 1211
+ S + + P+ F F + + P I L ++L+V++ PV+A+R I+
Sbjct: 1112 GIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIW 1171
Query: 1212 PA--------LKELRAKEEKVEEGPSEEIFTMEPLPHVHRESRARRSSYAFSHREGYANL 1263
P+ K L+A+E+ +++F R RRS+YAFSH+ GYA+L
Sbjct: 1172 PSESDKIQKHRKRLKAEEQWQRR---QQVF--------RRGVSTRRSAYAFSHQRGYADL 1220
Query: 1264 ITQGTILRR 1272
I+ G +R+
Sbjct: 1221 ISSGRSIRK 1229
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 922 bits (2382), Expect = 0.0
Identities = 515/1194 (43%), Positives = 739/1194 (61%), Gaps = 90/1194 (7%)
Query: 109 VQANNRAYNGQFKEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLII 168
V+AN+R YN +F+ Y N I T+KYN +FLP+NL+EQF RV+N +FL +
Sbjct: 15 VKANDREYNEKFQ-----------YADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCL 63
Query: 169 IILQSIPDISTLPWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFK 228
+ILQ IP+IS+L WF+ P+V ++ + A +D DD RHKSD +NNR ++L+ +
Sbjct: 64 LILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQ 123
Query: 229 QKKWQDLCVGDVVCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTH 288
+KW ++ VGD++ L + V AD+LLL+S+EP LCYVET ++DGETNLK R AL VT
Sbjct: 124 NEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTS 183
Query: 289 KELATIKKMASFQGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRNTDTCY 348
+ A I ++A F G V CE PN+++ F+G L W D K+SL+ ++LRGC +RNT C+
Sbjct: 184 ELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSWCF 243
Query: 349 GLVIYAGFDTKIMKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKE-- 406
G+VI+AG DTK+M+N GK KRT +D LMN LV+ IF L+CL + G S+ E
Sbjct: 244 GMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIF--GFLICLGIILAIGNSIWESQ 301
Query: 407 ----FKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDW 462
F+ ++ G S F FWS++I+L+ +P+S+++ E I LG+S FI+W
Sbjct: 302 TGDQFRTFLFWNEGEKSS--VFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINW 359
Query: 463 DVQMYYKPQDVPAKARSTSLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYG---- 518
D +MYY + +PA AR+T+LN+ LGQ+EYIFSDKTGTLTQNI+TF +C I+GR+YG
Sbjct: 360 DRKMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHD 419
Query: 519 ---PDSEATTRPKENPYLWNKFADGKLLFHNAALLHLVRTNGDEAVREFWRLLAICHTVM 575
+E T + + AD + F + L+ ++ GD V EF RLLA+CHTVM
Sbjct: 420 DLDQKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKM-GDPKVHEFLRLLALCHTVM 478
Query: 576 VRESPRERPDQLLYQAASPDEGALVTAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIM 635
E+ +L+YQ SPDEGALVTAARNFG++F SRT +T+TI ELG YQ+LA +
Sbjct: 479 SEEN---SAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFL 535
Query: 636 DFNSTRKRMSVLVRKPEGAICLYTKGADTVIFERLHRRGAMEFA-TEEALAAFAQETLRT 694
DFN+TRKRMSV+VR PEG I LY+KGADT++FE+LH + + T + L+ FA E LRT
Sbjct: 536 DFNNTRKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRT 595
Query: 695 LCLAYREVAEDIYEDWQQRHQEASLLLQNRAQALQ----------QLLGATAIEDRLQDG 744
L +AYR++ + +++W + ++A+ + R + + LLGATA+ED+LQ+G
Sbjct: 596 LAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEG 655
Query: 745 VPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENSN 804
V ET+ L +NIKIWVLTGDKQETA+NIG+AC +L+++M ++ I +N
Sbjct: 656 VIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDM-----NDVFVI-----AGNN 705
Query: 805 NLLTRESLSQVKLALV-INGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYA 863
+ RE L + K L N +F + +V +K Q + +D +E
Sbjct: 706 AVEVREELRKAKQNLFGQNRNFSNGHVVCEKK------QQLELDSIVEE--------TIT 751
Query: 864 RRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIV 923
+L+ L A S+V + ++LA C+ VICCRVTP QKA +V
Sbjct: 752 GDYALIINGHSLAHAL----------ESDVKND--LLELACMCKTVICCRVTPLQKAQVV 799
Query: 924 ALVKKYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLL 983
LVKKY VTLAIGDGAND++MIK+A +GVG++GQEG+QAV SD+ QF +LQRLLL
Sbjct: 800 ELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLL 859
Query: 984 VHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPV 1043
VHGRWSY R+CKFL YFFYK+ A +V WF + GF+ Q +Y+ WF+ LFN++Y++LPV
Sbjct: 860 VHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPV 919
Query: 1044 LYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISRD 1103
L +G+F+QDVS + S++ P+LY GQ + LFN F + HG+ TSLV FF+ +
Sbjct: 920 LAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYN 979
Query: 1104 TAGP--ASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTT 1161
AG +D+QSFAV +A S ++ +++++ L YWT + I S+ Y + T
Sbjct: 980 VAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTM 1039
Query: 1162 QSFWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLALRV----IFPALKEL 1217
S +F + P FPF+ ++ I LV+LL+ + PV+A R ++P L +
Sbjct: 1040 HSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQ 1099
Query: 1218 RAKEEKVEEGPSEEIFTMEPLPHVHRESRARRSSYAFSHREGYANLITQGTILR 1271
+ +K ++ + + P R S +RRS YAF+H+EGY LIT G +R
Sbjct: 1100 IRRWQKAQK-KARPPSSRRPRT---RRSSSRRSGYAFAHQEGYGELITSGKNMR 1149
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 922 bits (2382), Expect = 0.0
Identities = 529/1229 (43%), Positives = 744/1229 (60%), Gaps = 103/1229 (8%)
Query: 108 KVQANNRAYNGQFKEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLI 167
+ +AN+R YN +F+ Y +N I+T+KYN +FLP+NL+EQF V+N +FL
Sbjct: 48 RARANDREYNEKFQ-----------YASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLF 96
Query: 168 IIILQSIPDISTLPWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSF 227
++ILQ IP IS+L WF+ P+V +L I A +D DD RHKSD +NNR Q+L+
Sbjct: 97 LLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGIL 156
Query: 228 KQKKWQDLCVGDVVCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVT 287
+Q++W ++CVGD++ L + V AD+LLL+S+EP LCY+ET ++DGETN+K RQA+ VT
Sbjct: 157 QQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVT 216
Query: 288 HKELATIKKMASFQGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRNTDTC 347
EL I K+A F G V CE PN+++ F G L W + K+ L N+LLRGC +RNT+ C
Sbjct: 217 -SELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWC 275
Query: 348 YGLVIYAGFDTKIMKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKE- 406
+GLVI+AG DTK+M+N G+ KRT +D LMN LV+ IF +V + ++LA G E
Sbjct: 276 FGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEV 335
Query: 407 -FKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQ 465
+ Y S F FWS++I+L+ +P+S+++ E I LG+S FI+WD +
Sbjct: 336 GMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKK 395
Query: 466 MYYKPQDVPAKARSTSLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGP------ 519
M+ + PA+AR+T+LN+ LGQVEYIFSDKTGTLTQNI+ FNKC I+G YG
Sbjct: 396 MFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG 455
Query: 520 -DSEATTRPKENPYLWNKFADGKLLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRE 578
+E RP+ + +N AD K LF + +LL V+ GD EF+RLL++CHTVM
Sbjct: 456 HKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKI-GDPHTHEFFRLLSLCHTVM--- 511
Query: 579 SPRERPDQLLYQAASPDEGALVTAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIMDFN 638
S + +L Y+A SPDEGALVTAARNFG+VF SRT T+T+ E+G YQ+LAI+DFN
Sbjct: 512 SEEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFN 571
Query: 639 STRKRMSVLVRKPEGAICLYTKGADTVIFERLHR-RGAMEFATEEALAAFAQETLRTLCL 697
+ RKRMSV+VR PEG I LY KGADT++ +RLH + T + L +A E LRTL L
Sbjct: 572 NIRKRMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVL 631
Query: 698 AYREVAEDIYEDWQQRHQEASLLLQNRAQAL----------QQLLGATAIEDRLQDGVPE 747
AY+++ E+ YE+W +R +ASL +R L LLGATAIED+LQ GVPE
Sbjct: 632 AYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPE 691
Query: 748 TIKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENSNNLL 807
TI L +NIKIWVLTGDKQETAVNIG++C++L+++M E + + +L
Sbjct: 692 TIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDM-----------TEVFIVTGHTVL 740
Query: 808 -TRESLSQVKLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRL 866
RE L + + +K++ S R G + +D L + +L
Sbjct: 741 EVREELRKAR----------EKMMDSSRSVGN---------------GFTYQDKLSSSKL 775
Query: 867 SLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALV 926
+ + A S A + E E F++ A C+AVICCRVTP QKA +V LV
Sbjct: 776 TSVLEAVAGEYALVINGHSLA-HALEADMELEFLETACACKAVICCRVTPLQKAQVVELV 834
Query: 927 KKYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHG 986
KKY + VTLAIGDGAND++MIKTA +GVG++GQEG+QAV SD+ QF FLQRLLLVHG
Sbjct: 835 KKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHG 894
Query: 987 RWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYI 1046
RWSY+R+CKFL YFFYK+ A MV WF + GF+ Q +Y+ +F+ L+N++Y++LPVL +
Sbjct: 895 RWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAM 954
Query: 1047 GLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISRDTA- 1105
G+F+QDV ++S+E P+LY GQ + LFN F IA G+ TS++ FF+ + D
Sbjct: 955 GVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATR 1014
Query: 1106 -GPASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSF 1164
+D+QSFAV VA S ++ +++++ L YWTA+ I SL Y + S
Sbjct: 1015 DDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSN 1074
Query: 1165 WLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLALRVIFPALK--------- 1215
LF + P F F+ + ++ P++ L ++L+ + PV+A R + LK
Sbjct: 1075 GLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRY 1134
Query: 1216 -ELRAKEEKVEEGPSEEIFTMEPLPHVHRESRARRSSYAFSHREGYANLITQGTILRRGP 1274
+L K++K + + + +RRS YAFSH+EG+ LI G +R
Sbjct: 1135 TQLVRKKQKAQHRCMRRV----------GRTGSRRSGYAFSHQEGFGELIMSGKNMRLSS 1184
Query: 1275 GVSSDIAS-------ESLDPSDEEAASSP 1296
S + ESL ++ASSP
Sbjct: 1185 LALSSFTTRSSSSWIESLRRKKSDSASSP 1213
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 693 bits (1788), Expect = 0.0
Identities = 410/1055 (38%), Positives = 616/1055 (58%), Gaps = 101/1055 (9%)
Query: 132 KYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMVC 191
K++ N I TAKY+ +FLP LYEQ R +N FFL I +LQ IPD+S ++ P++
Sbjct: 67 KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLII 126
Query: 192 LLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVPA 251
+L I +++V+D RHK+D A+N + +L + W+++ VGD+V + +PA
Sbjct: 127 ILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPA 186
Query: 252 DMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPNS 311
D++LL+S+EP ++CYVET ++DGETNLK RQ L T ++ T + + GT+ CE PN
Sbjct: 187 DVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHT-ADMQTREVLMKLSGTIECEGPNR 245
Query: 312 RMHHFVGCLEWNDKKY-SLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKIHLK 370
++ F G L + K +L +LLRG ++RNT +G+V+Y G DTK+M+N K LK
Sbjct: 246 HLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLK 305
Query: 371 RTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESF-FV 429
R+ ++ + N ++V+F ++++ LV + G + + + ++Y+ + +S ++F +
Sbjct: 306 RSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTS---DNFGYN 362
Query: 430 FWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQV 489
+F+IL + IP+S+ + E + ++FI+WD MYY D PA AR+++LN+ LGQV
Sbjct: 363 LLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQV 422
Query: 490 EYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYL-WNKFADGKLLFHNAA 548
+Y+FSDKTGTLT NI+ F KC I+G YG E P + + F +
Sbjct: 423 KYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPR 482
Query: 549 LLHLVRTNGDEA--VREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNF 606
LL + A ++EF LLA+CHTV+ P + D ++YQA+SPDE ALV A+
Sbjct: 483 LLKNIEDRHPTAPCIQEFLTLLAVCHTVV----PEKDGDNIIYQASSPDEAALVKGAKKL 538
Query: 607 GYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTVI 666
G+VF +RT +V I +G+E+ + +L +++F+S RKRMSV+VR P G + LY KGAD VI
Sbjct: 539 GFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVI 598
Query: 667 FERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLLLQNRAQ 726
FERL + T L FA E LRTLC+AY +++E+ YE+W + +QEAS +L++RAQ
Sbjct: 599 FERLSKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQ 658
Query: 727 ALQQ----------LLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFA 776
L++ LLGATAIEDRLQ GVPETI L K+ IKIWVLTGDKQETA+NIG++
Sbjct: 659 RLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYS 718
Query: 777 CELLSENMLILEEKEIS-----RILETYWENSNNLLTRESLSQVKLALVINGDFLDKLLV 831
C L+S+NM ++ KE S + + + NLL +E+ +AL+I+G L K +
Sbjct: 719 CRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKEN----DVALIIDGHTL-KYAL 773
Query: 832 SLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDSRARRSS 891
S + RR FL L+L C+
Sbjct: 774 SF---------------------EVRRSFL---DLALSCK-------------------- 789
Query: 892 EVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTAD 951
AVICCRV+P QK+ IV +VKK + +TLAIGDGAND+ MI+TA
Sbjct: 790 ----------------AVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAH 833
Query: 952 VGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFFYKSMASMMVQ 1011
VGVG++G EGMQA NSD+ + QF +L++LLLVHG WSY R+ K + Y FYK++ +++
Sbjct: 834 VGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIE 893
Query: 1012 VWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVVGQKD 1071
+WFA NGF+GQ L+E W + L+N++++ LP +G+FE+ + E L P+LY + Q
Sbjct: 894 LWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNG 953
Query: 1072 ELFNYWVFVQAIAHGVTTSLVNFFMTL-WISRD---TAGPAS---FSDHQSFAVVVALSC 1124
E FN VF + + SL+ F+ + + D T+G A+ F + + VV C
Sbjct: 954 EGFNTKVFWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVC 1013
Query: 1125 LLSITMEVILIIKYWTALCVATILLSLGFYAIMTT 1159
L +E K+ ++L L F+ I +T
Sbjct: 1014 -LKAGLETTAWTKFSHLAVWGSMLTWLVFFGIYST 1047
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 663 bits (1711), Expect = 0.0
Identities = 393/1112 (35%), Positives = 618/1112 (55%), Gaps = 113/1112 (10%)
Query: 129 QRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTP 188
Q K+ N + TAKYN +FLP LY QF R +N FFL I +LQ IPD+S ++ P
Sbjct: 45 QLTKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVP 104
Query: 189 MVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNI 248
++ +L + A +++++D+ RHK+D A+N + Q+L +++ W+ + VGD+V ++
Sbjct: 105 LLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEY 164
Query: 249 VPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEA 308
+PAD +LL+S+EP ++CY+ET ++DGETNLK RQ L T ++ + + G + CE+
Sbjct: 165 IPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPAT-SDIKDVDSLMRISGRIECES 223
Query: 309 PNSRMHHFVGCLEWNDK-KYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKI 367
PN ++ FVG + + L +LLRG ++RNT +G+V+Y G DTK+M+N
Sbjct: 224 PNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSP 283
Query: 368 HLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESF 427
LK + ++ + N ++++F ++ + LV + G + +YL+ +G A+
Sbjct: 284 PLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGG--ASNFG 341
Query: 428 FVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLG 487
F +F+IL + IP+S+ + E + + FI+WD+ M+Y+P D A AR+++LN+ LG
Sbjct: 342 LNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELG 401
Query: 488 QVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFHNA 547
QV+YIFSDKTGTLT N++ F KC I+G YG +S+ F D K F ++
Sbjct: 402 QVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQ--------------FGDEK-TFSDS 446
Query: 548 ALLHLVRTNGDEA--VREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARN 605
+LL ++ N A + EF ++A+CHT + P D+++YQAASPDEGALV AA+
Sbjct: 447 SLLENLQNNHPTAPIICEFLTMMAVCHTAV----PEREGDKIIYQAASPDEGALVRAAKQ 502
Query: 606 FGYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTV 665
+VF RT D+V I LG+E Y++L +++F S RKRMSV+VR P G + LY KGADTV
Sbjct: 503 LNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTV 562
Query: 666 IFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLLLQNRA 725
I++RL + T + L FA E LRTLC A E++E +++W+ +Q AS +QNR
Sbjct: 563 IYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRL 622
Query: 726 QALQ----------QLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGF 775
L+ QLLGATAIED+LQD VPETI+ L K++IKIW+LTGDKQETA+NIG
Sbjct: 623 LKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGH 682
Query: 776 ACELLSEN--MLILEEKEISRILETYWENSNNL---LTRESLSQVKLALVINGDFLDKLL 830
+C+LL +N M+++ E + ET + L L +E+ AL+I+G L L
Sbjct: 683 SCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKEN----DFALIIDGKTLKYAL 738
Query: 831 VSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDSRARRS 890
++ Y L+L C+ +P
Sbjct: 739 TFGVRQ-------------------------YFLDLALSCKAVICCRVSP---------- 763
Query: 891 SEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTA 950
LQ+ V++ K V+ TLAIGDGAND++MI+TA
Sbjct: 764 ---LQKSEVVEMVKKQVKVV-----------------------TLAIGDGANDVSMIQTA 797
Query: 951 DVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFFYKSMASMMV 1010
VGVG++G EG+QA +SD+ + QF +L+ LL++HG W+Y R+ K + Y FYK++ ++
Sbjct: 798 HVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYII 857
Query: 1011 QVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVVGQK 1070
++WFA NGF+GQ L+E W + L+N++++ +P L +G+FE+ E L+ PELY Q
Sbjct: 858 EIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQN 917
Query: 1071 DELFNYWVFVQAIAHGVTTSLVNFFMTL-WISRDTA-GPASFSDHQSFAVVVALSCLLSI 1128
FN VF +G+ S++ F+ L + TA G SD+ V ++++
Sbjct: 918 ALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITV 977
Query: 1129 TMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSVMSSPS 1188
++ L YWT I S+ + + S W + P + + +++ S
Sbjct: 978 CLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLW---PAIPMAPDMSGEAAMLFSSG 1034
Query: 1189 ILLVVLLSVSINTFPVLALRVIFPALKELRAK 1220
+ + LL + + + L L V++ +K K
Sbjct: 1035 VFWMGLLFIPVAS---LLLDVVYKVIKRTAFK 1063
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 659 bits (1701), Expect = 0.0
Identities = 394/1117 (35%), Positives = 623/1117 (55%), Gaps = 108/1117 (9%)
Query: 129 QRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTP 188
Q K+ N + TAKYN +FLP LY QF R +N FFL I +LQ IPD+S ++ P
Sbjct: 45 QLTKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVP 104
Query: 189 MVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNI 248
++ +L + A +++++D+ RHK+D A+N + Q+L +++ W+ + VG++V +
Sbjct: 105 LLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEH 164
Query: 249 VPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEA 308
+PAD++ L+S+EP ++CY+ET ++DGETNLK RQ L T ++ + + G + CE+
Sbjct: 165 LPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPAT-SDIKDVDSLMRISGRIECES 223
Query: 309 PNSRMHHFVGCLEWNDK-KYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKI 367
PN ++ FVG + + L +LLRG ++RNT +G+V+Y G DTK+M+N
Sbjct: 224 PNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSP 283
Query: 368 HLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESF 427
LK + ++ + N ++++F ++ + LV + G + +YL+ +G A+
Sbjct: 284 PLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGG--ASNFG 341
Query: 428 FVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLG 487
F +F+IL + IP+S+ + E + + FI+WD+ M+Y+P D A AR+++LN+ LG
Sbjct: 342 LNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELG 401
Query: 488 QVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKE---NPYLW--NKFADGKL 542
QV+YIFSDKTGTLT N++ F KC I+G YG E P++ +P W ++F D K
Sbjct: 402 QVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPE----PEDYGCSPDEWQNSQFGDEK- 456
Query: 543 LFHNAALLHLVRTNGDEA--VREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALV 600
F +++LL ++ N A + EF ++A+CHT + P D+++YQAASPDEGALV
Sbjct: 457 TFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAV----PEREGDKIIYQAASPDEGALV 512
Query: 601 TAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTK 660
AA+ +VF RT D+V I LG+E Y++L +++F S RKRMSV+VR P G + LY K
Sbjct: 513 RAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCK 572
Query: 661 GADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLL 720
GADTVI++RL + T + L FA E LRTLC A E++E +++W+ +Q AS
Sbjct: 573 GADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTS 632
Query: 721 LQNRAQALQ----------QLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETA 770
+QNR L+ QLLGATAIED+LQD VPETI+ L K++IKIW+LTGDKQETA
Sbjct: 633 VQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETA 692
Query: 771 VNIGFACELLSEN--MLILEEKEISRILETYWENSNNL---LTRESLSQVKLALVINGDF 825
+NIG +C+LL +N M+++ E + ET + L L +E+ AL+I+G
Sbjct: 693 INIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKEN----DFALIIDGKT 748
Query: 826 LDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDS 885
L L ++ Y L+L C+ +P
Sbjct: 749 LKYALTFGVRQ-------------------------YFLDLALSCKAVICCRVSP----- 778
Query: 886 RARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDGANDIN 945
LQ+ V++ K V+ TLAIGDGAND++
Sbjct: 779 --------LQKSEVVEMVKKQVKVV-----------------------TLAIGDGANDVS 807
Query: 946 MIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFFYKSM 1005
MI+TA VGVG++G EG+QA +SD+ + QF +L+ LL++HG W+Y R+ K + Y FYK++
Sbjct: 808 MIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNI 867
Query: 1006 ASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELY 1065
++++WFA NGF+GQ L+E W + L+N++++ +P L +G+FE+ E L+ PELY
Sbjct: 868 VLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELY 927
Query: 1066 VVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTL-WISRDTA-GPASFSDHQSFAVVVALS 1123
Q FN VF +G+ S++ F+ L + TA G SD+ V
Sbjct: 928 KTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTF 987
Query: 1124 CLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSV 1183
++++ ++ L YWT I S+ + + S W + P + + ++
Sbjct: 988 VVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLW---PAIPMAPDMSGEAAM 1044
Query: 1184 MSSPSILLVVLLSVSINTFPVLALRVIFPALKELRAK 1220
+ S + + LL + + + L L V++ +K K
Sbjct: 1045 LFSSGVFWMGLLFIPVAS---LLLDVVYKVIKRTAFK 1078
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 535 bits (1378), Expect = e-151
Identities = 372/1138 (32%), Positives = 592/1138 (52%), Gaps = 142/1138 (12%)
Query: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
++Y N I ++KY F++F+P NL+EQF RV+N +FLII ++Q I D T P S P+
Sbjct: 43 QRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTSPVTS-GLPLF 101
Query: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
++ + A + +D RHK+D A+N P + +K+ + L VGD+V +++D P
Sbjct: 102 FVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFP 161
Query: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
D++ L+S C+V T +DGE++ K A+ T K T + + T+ CE P
Sbjct: 162 CDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEEDIGGLHATIECEQPQ 220
Query: 311 SRMHHFVGCL----EWNDKKYS-LDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCG 365
++ FVG + + ND L NLLLRG ++NT+ +G+ IY G +TK+ N
Sbjct: 221 PDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQ 280
Query: 366 KIHLKRTKLDLLMNKLVVV---IFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGS-- 420
KR+ ++ MN ++V I IS L+ VL + + + F+D +Y
Sbjct: 281 SKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMW--QSEPFRDEPWYNQKTESERQ 338
Query: 421 -SVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARS 479
++ ++F F +F++L + IP+SM++ E S FI WD M+ + +
Sbjct: 339 RNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNT 398
Query: 480 TSLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFAD 539
+ LN+ LGQVEYIF+DKTGTLT+N + F +CCI G VY P + +
Sbjct: 399 SDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVP---------------HVICN 443
Query: 540 GKLLFHNAALLHL---VRTNGDEAVREFWRLLAICHTVMVR-----ESPRERPD---QLL 588
G++L ++ + + NG E F+R L +CHTV V+ + PR+ PD +
Sbjct: 444 GQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCV 503
Query: 589 YQAASPDEGALVTAARNFGYVFLSRTQDTVTIM--ELGEERVYQVLAIMDFNSTRKRMSV 646
Y ++SPDE ALV + G+ +L + + I+ E ER +++L I+ F+S R+RMSV
Sbjct: 504 YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIER-FELLEILSFDSVRRRMSV 562
Query: 647 LVRKPEGAICLYTKGADTVIFERLHRRGAMEFATEEALAAF---AQETLRTLCLAYREVA 703
+V+ G I L+ KGAD+ IF R+ +E ++ A A E LRTLC+AY+ +
Sbjct: 563 IVKSATGEIYLFCKGADSSIFPRV-----IEGKVDQIRARVERNAVEGLRTLCVAYKRLI 617
Query: 704 EDIYEDWQQRHQEASLLLQNR----AQALQQ------LLGATAIEDRLQDGVPETIKCLK 753
++ YE + Q A + LQ+R A+A +Q LLGATA+EDRLQ+ +TI+ L+
Sbjct: 618 QEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQ 677
Query: 754 KSNIKIWVLTGDKQETAVNIGFACELLSENMLIL-------EEKEISRIL----ETYWEN 802
K+ IK+WVLTGDK ETA +AC+L N +L EE+ + +L +T +
Sbjct: 678 KAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRH 737
Query: 803 SNNLLTRESLSQVKLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLY 862
S + LTR++LS + + G +D +SL +PR + N E + E
Sbjct: 738 SGS-LTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLE---------- 786
Query: 863 ARRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALI 922
+CR C AV+CCR+ P QKA I
Sbjct: 787 ------ICR---------------------------------SCSAVLCCRMAPLQKAQI 807
Query: 923 VALVK--KYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQR 980
V L+K K H +TLAIGDGAND++MI A VG+G+ G+EG QA +NSD+ + +F L++
Sbjct: 808 VKLIKFSKEHP-ITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKK 866
Query: 981 LLLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYST 1040
+LLVHG + Y+RI + ++YFFYK++ + Q + + GF+ Q LY+ +L L+N+ +++
Sbjct: 867 MLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTS 926
Query: 1041 LPVLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWI 1100
LP+L L EQ V + P LY K+ L + VF+ G+ +LV FF ++
Sbjct: 927 LPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFV 986
Query: 1101 SRDT--AGPASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMT 1158
+T + +F +V + ++T+++ L YWT + I SL FY + +
Sbjct: 987 FENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFS 1046
Query: 1159 TTTQSFWLFRVSPTTFPFL------YADLSVMSSPSILLVVLLSVSINTFPVLALRVI 1210
W +PFL Y + ++SS L ++L V+I+ P + +V+
Sbjct: 1047 L----LW----GGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVL 1096
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 535 bits (1378), Expect = e-151
Identities = 372/1138 (32%), Positives = 592/1138 (52%), Gaps = 142/1138 (12%)
Query: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
++Y N I ++KY F++F+P NL+EQF RV+N +FLII ++Q I D T P S P+
Sbjct: 43 QRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTSPVTS-GLPLF 101
Query: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
++ + A + +D RHK+D A+N P + +K+ + L VGD+V +++D P
Sbjct: 102 FVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFP 161
Query: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
D++ L+S C+V T +DGE++ K A+ T K T + + T+ CE P
Sbjct: 162 CDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDT-KGFHTEEDIGGLHATIECEQPQ 220
Query: 311 SRMHHFVGCL----EWNDKKYS-LDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCG 365
++ FVG + + ND L NLLLRG ++NT+ +G+ IY G +TK+ N
Sbjct: 221 PDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQ 280
Query: 366 KIHLKRTKLDLLMNKLVVV---IFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGS-- 420
KR+ ++ MN ++V I IS L+ VL + + + F+D +Y
Sbjct: 281 SKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMW--QSEPFRDEPWYNQKTESERQ 338
Query: 421 -SVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARS 479
++ ++F F +F++L + IP+SM++ E S FI WD M+ + +
Sbjct: 339 RNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNT 398
Query: 480 TSLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFAD 539
+ LN+ LGQVEYIF+DKTGTLT+N + F +CCI G VY P + +
Sbjct: 399 SDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVP---------------HVICN 443
Query: 540 GKLLFHNAALLHL---VRTNGDEAVREFWRLLAICHTVMVR-----ESPRERPD---QLL 588
G++L ++ + + NG E F+R L +CHTV V+ + PR+ PD +
Sbjct: 444 GQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCV 503
Query: 589 YQAASPDEGALVTAARNFGYVFLSRTQDTVTIM--ELGEERVYQVLAIMDFNSTRKRMSV 646
Y ++SPDE ALV + G+ +L + + I+ E ER +++L I+ F+S R+RMSV
Sbjct: 504 YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIER-FELLEILSFDSVRRRMSV 562
Query: 647 LVRKPEGAICLYTKGADTVIFERLHRRGAMEFATEEALAAF---AQETLRTLCLAYREVA 703
+V+ G I L+ KGAD+ IF R+ +E ++ A A E LRTLC+AY+ +
Sbjct: 563 IVKSATGEIYLFCKGADSSIFPRV-----IEGKVDQIRARVERNAVEGLRTLCVAYKRLI 617
Query: 704 EDIYEDWQQRHQEASLLLQNR----AQALQQ------LLGATAIEDRLQDGVPETIKCLK 753
++ YE + Q A + LQ+R A+A +Q LLGATA+EDRLQ+ +TI+ L+
Sbjct: 618 QEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQ 677
Query: 754 KSNIKIWVLTGDKQETAVNIGFACELLSENMLIL-------EEKEISRIL----ETYWEN 802
K+ IK+WVLTGDK ETA +AC+L N +L EE+ + +L +T +
Sbjct: 678 KAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRH 737
Query: 803 SNNLLTRESLSQVKLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLY 862
S + LTR++LS + + G +D +SL +PR + N E + E
Sbjct: 738 SGS-LTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLE---------- 786
Query: 863 ARRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALI 922
+CR C AV+CCR+ P QKA I
Sbjct: 787 ------ICR---------------------------------SCSAVLCCRMAPLQKAQI 807
Query: 923 VALVK--KYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQR 980
V L+K K H +TLAIGDGAND++MI A VG+G+ G+EG QA +NSD+ + +F L++
Sbjct: 808 VKLIKFSKEHP-ITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKK 866
Query: 981 LLLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYST 1040
+LLVHG + Y+RI + ++YFFYK++ + Q + + GF+ Q LY+ +L L+N+ +++
Sbjct: 867 MLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTS 926
Query: 1041 LPVLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWI 1100
LP+L L EQ V + P LY K+ L + VF+ G+ +LV FF ++
Sbjct: 927 LPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFV 986
Query: 1101 SRDT--AGPASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMT 1158
+T + +F +V + ++T+++ L YWT + I SL FY + +
Sbjct: 987 FENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFS 1046
Query: 1159 TTTQSFWLFRVSPTTFPFL------YADLSVMSSPSILLVVLLSVSINTFPVLALRVI 1210
W +PFL Y + ++SS L ++L V+I+ P + +V+
Sbjct: 1047 L----LW----GGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVL 1096
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 524 bits (1349), Expect = e-148
Identities = 355/1119 (31%), Positives = 569/1119 (50%), Gaps = 127/1119 (11%)
Query: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
+K+ N I ++KY ++F+P NL+EQF RV+N +FLII ++Q + D T P S P+
Sbjct: 37 QKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSPVTS-GLPLF 95
Query: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
++ + A + +D RH SD +N P ++ + + +++ VGD+V + KD I P
Sbjct: 96 FVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFP 155
Query: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
AD++LL+S C+V T +DGETNLK A+ T L T+ + + + C+ P
Sbjct: 156 ADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETAL-LQTVANLDTLVAVIECQQPE 214
Query: 311 SRMHHFVGCL----EWNDKKYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGK 366
+ ++ F+G + + + L +LLLRG R++NT +G+ +Y G +TK+ N
Sbjct: 215 ADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKS 274
Query: 367 IHLKRTKLDLLMNKLVV---VIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVH---GS 420
KR+ ++ MN ++ VI IS ++ +L + + +E D +Y S
Sbjct: 275 KSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTW--QAEEKWDEPWYNQKTEHQRNS 332
Query: 421 SVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARST 480
S F +FL+L + IP+S+++ E S FI WD+ +Y++ D A+ ++
Sbjct: 333 SKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTS 392
Query: 481 SLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADG 540
LN+ LGQVEY+F+DKTGTLT+N + F +C I+G Y + P ++G
Sbjct: 393 DLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTP----DSSEG 448
Query: 541 KL-----LFHNAALLHLVRT--------NGDEAVRE---FWRLLAICHTVMVRESPRE-- 582
L L H L HL + N E ++E F++ +++CHTV + +
Sbjct: 449 NLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCT 508
Query: 583 ---------RPDQLLYQAASPDEGALVTAARNFGYVFLSRTQDTVTIMELGEERVYQVLA 633
P QL Y A+SPDE ALV AA G VF+ +++T+ + LG+ Y++L
Sbjct: 509 GDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLH 568
Query: 634 IMDFNSTRKRMSVLVRKPEGAICLYTKGADTVIFERLHRRGAMEFATEEALAAFAQETLR 693
I++F+S R+RMSV+V+ P G L+ KGA++ I + G T + FA + LR
Sbjct: 569 ILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKC--IGGEIEKTRIHVDEFALKGLR 626
Query: 694 TLCLAYREVAEDIYEDWQQRHQEASLLLQNRAQALQQ----------LLGATAIEDRLQD 743
TLC+AYR+ YE+ +R EA LQ R + L LLGATA+EDRLQD
Sbjct: 627 TLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQD 686
Query: 744 GVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENS 803
V ETI+ L+ + IK+WVLTGDK ETAV++ +C M ILE
Sbjct: 687 KVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILE--------------- 731
Query: 804 NNLLTRESLSQVKLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYA 863
L+ ++S S+ ++ R LA+ + D Q
Sbjct: 732 --LINQKSDSE------------------CAEQLRQLARRITEDHVIQH----------- 760
Query: 864 RRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIV 923
L S A R E L F+++ C AV+CCR+ P QKA ++
Sbjct: 761 ------------GLVVDGTSLSLALREHEKL----FMEVCRNCSAVLCCRMAPLQKAKVI 804
Query: 924 ALVK-KYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLL 982
L+K + +TLA+GDGAND++MI+ A VG+G+ G+EG QA +NSD+ + +F FL +LL
Sbjct: 805 RLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLL 864
Query: 983 LVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLP 1042
VHG + Y+RI ++YFFYK++ + Q + Y F+ Q LY+ +L L+N+ +++LP
Sbjct: 865 FVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLP 924
Query: 1043 VLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMT-LWIS 1101
+L L EQ V KP LY K+ L + F+ G + + + FF + L I
Sbjct: 925 ILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIG 984
Query: 1102 RDTA--GPASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTT 1159
+DT+ G + +F +V ++++T+++ L +WT + S+ FY + +
Sbjct: 985 KDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSL 1044
Query: 1160 TTQS-FWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSV 1197
W F S + + + ++SS S ++L V
Sbjct: 1045 FYGGILWPFLGSQNMY---FVFIQLLSSGSAWFAIILMV 1080
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 517 bits (1332), Expect = e-146
Identities = 346/1120 (30%), Positives = 568/1120 (50%), Gaps = 110/1120 (9%)
Query: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
+++ N I ++KY ++FLP NL+EQF R++N +FLII ++Q D T P S P+
Sbjct: 41 QRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTS-GLPLF 99
Query: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
++ + A + +D RH++D +N I+ +K+ + + VGDVV ++ D P
Sbjct: 100 FVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFP 159
Query: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
D++LL+S CYV T +DGE+N K A+ T L T + + + + + CE P
Sbjct: 160 CDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIA-LCTAESIDTLRAAIECEQPQ 218
Query: 311 SRMHHFVGCLEWNDKKY-----SLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCG 365
++ FVG + SL NLLL+G ++NT+ YG+ +Y G +TK+ N
Sbjct: 219 PDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQ 278
Query: 366 KIHLKRTKLDLLMNK-LVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAA 424
KR+ ++ +N L+V +FI + + + + + D +Y
Sbjct: 279 GKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETL 338
Query: 425 E---SFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTS 481
+ F F SF++L + IP+SM++ E S FI WD Y + + A ++
Sbjct: 339 KVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSD 398
Query: 482 LNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGK 541
LN+ LGQV+Y+F+DKTGTLT+N + F +CCI G Y ++ + DG
Sbjct: 399 LNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT--------DGT 450
Query: 542 LLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRESPR----ERPDQLLYQAASPDEG 597
L + + V N +E F R L +CHTV ++ + +L Y ++SPDE
Sbjct: 451 LTYFDK-----VDKNREEL---FLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEI 502
Query: 598 ALVTAARNFGYVFLSRTQDTVTIMELGEE-RVYQVLAIMDFNSTRKRMSVLVRKPEGAIC 656
ALV A+ +G+ FL + + +E Y++L ++F++ R+RMSV+V+ EG I
Sbjct: 503 ALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDIL 562
Query: 657 LYTKGADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQE 716
L+ KGAD+ +F R+ T+ + A + RTLC+A++E+A D YE ++ E
Sbjct: 563 LFCKGADSAVFPRVQNHEIE--LTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIE 620
Query: 717 ASLLLQNRAQALQQ----------LLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDK 766
A + LQ+R + +++ L+GATA+ED+LQD ETI+ L + +K+WVLTGDK
Sbjct: 621 AKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDK 680
Query: 767 QETAVNIGFACELLSENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALVINGDFL 826
ETA + +AC L N +LE LT +++ + + D L
Sbjct: 681 METAKSTCYACRLFQTNTELLE------------------LTTKTIEESER----KEDRL 718
Query: 827 DKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYA----RRLSLLCRRFGLPLAAPPA 882
+LL+ RK+ E +S R F A + L+ L L +
Sbjct: 719 HELLIEYRKK------------LLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSS 766
Query: 883 QDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYH-QVVTLAIGDGA 941
QDS + + F+ + KC AV+CCR+ P QKA IV +VK +TL+IGDGA
Sbjct: 767 QDSSSNNYKSI-----FLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGA 821
Query: 942 NDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFF 1001
ND++MI + VG+G+ G+EG QA +NSD+ + +F L++LLL HG YVRI ++YFF
Sbjct: 822 NDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFF 881
Query: 1002 YKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEK 1061
YK++ ++ Q + + GF+ QPLY+ +L ++N+ +++LP+L L EQ ++ +
Sbjct: 882 YKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSD 941
Query: 1062 PELYVVGQKDEL-----FNYWVFVQAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSF 1116
P LY+ + + F YW F+ A G +F+ S + G + +F
Sbjct: 942 PRLYMKISGNAMLQLGPFLYWTFLAAF-EGTVFFFGTYFLFQTASLEENG--KVYGNWTF 998
Query: 1117 AVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPF 1176
+V + ++T+++ L ++WT + I SL FY F+ F +PF
Sbjct: 999 GTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYV--------FFSFFWGGIIWPF 1050
Query: 1177 L------YADLSVMSSPSILLVVLLSVSINTFPVLALRVI 1210
L + ++SS S L ++L + I+ FP + L V+
Sbjct: 1051 LKQQRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVL 1090
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 517 bits (1332), Expect = e-146
Identities = 346/1120 (30%), Positives = 568/1120 (50%), Gaps = 110/1120 (9%)
Query: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
+++ N I ++KY ++FLP NL+EQF R++N +FLII ++Q D T P S P+
Sbjct: 41 QRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTS-GLPLF 99
Query: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
++ + A + +D RH++D +N I+ +K+ + + VGDVV ++ D P
Sbjct: 100 FVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFP 159
Query: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
D++LL+S CYV T +DGE+N K A+ T L T + + + + + CE P
Sbjct: 160 CDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIA-LCTAESIDTLRAAIECEQPQ 218
Query: 311 SRMHHFVGCLEWNDKKY-----SLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCG 365
++ FVG + SL NLLL+G ++NT+ YG+ +Y G +TK+ N
Sbjct: 219 PDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQ 278
Query: 366 KIHLKRTKLDLLMNK-LVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAA 424
KR+ ++ +N L+V +FI + + + + + D +Y
Sbjct: 279 GKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETL 338
Query: 425 E---SFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTS 481
+ F F SF++L + IP+SM++ E S FI WD Y + + A ++
Sbjct: 339 KVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSD 398
Query: 482 LNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGK 541
LN+ LGQV+Y+F+DKTGTLT+N + F +CCI G Y ++ + DG
Sbjct: 399 LNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT--------DGT 450
Query: 542 LLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRESPR----ERPDQLLYQAASPDEG 597
L + + V N +E F R L +CHTV ++ + +L Y ++SPDE
Sbjct: 451 LTYFDK-----VDKNREEL---FLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEI 502
Query: 598 ALVTAARNFGYVFLSRTQDTVTIMELGEE-RVYQVLAIMDFNSTRKRMSVLVRKPEGAIC 656
ALV A+ +G+ FL + + +E Y++L ++F++ R+RMSV+V+ EG I
Sbjct: 503 ALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDIL 562
Query: 657 LYTKGADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQE 716
L+ KGAD+ +F R+ T+ + A + RTLC+A++E+A D YE ++ E
Sbjct: 563 LFCKGADSAVFPRVQNHEIE--LTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIE 620
Query: 717 ASLLLQNRAQALQQ----------LLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDK 766
A + LQ+R + +++ L+GATA+ED+LQD ETI+ L + +K+WVLTGDK
Sbjct: 621 AKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDK 680
Query: 767 QETAVNIGFACELLSENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALVINGDFL 826
ETA + +AC L N +LE LT +++ + + D L
Sbjct: 681 METAKSTCYACRLFQTNTELLE------------------LTTKTIEESER----KEDRL 718
Query: 827 DKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYA----RRLSLLCRRFGLPLAAPPA 882
+LL+ RK+ E +S R F A + L+ L L +
Sbjct: 719 HELLIEYRKK------------LLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSS 766
Query: 883 QDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYH-QVVTLAIGDGA 941
QDS + + F+ + KC AV+CCR+ P QKA IV +VK +TL+IGDGA
Sbjct: 767 QDSSSNNYKSI-----FLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGA 821
Query: 942 NDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFF 1001
ND++MI + VG+G+ G+EG QA +NSD+ + +F L++LLL HG YVRI ++YFF
Sbjct: 822 NDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFF 881
Query: 1002 YKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEK 1061
YK++ ++ Q + + GF+ QPLY+ +L ++N+ +++LP+L L EQ ++ +
Sbjct: 882 YKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSD 941
Query: 1062 PELYVVGQKDEL-----FNYWVFVQAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSF 1116
P LY+ + + F YW F+ A G +F+ S + G + +F
Sbjct: 942 PRLYMKISGNAMLQLGPFLYWTFLAAF-EGTVFFFGTYFLFQTASLEENG--KVYGNWTF 998
Query: 1117 AVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPF 1176
+V + ++T+++ L ++WT + I SL FY F+ F +PF
Sbjct: 999 GTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYV--------FFSFFWGGIIWPF 1050
Query: 1177 L------YADLSVMSSPSILLVVLLSVSINTFPVLALRVI 1210
L + ++SS S L ++L + I+ FP + L V+
Sbjct: 1051 LKQQRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVL 1090
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 348 bits (893), Expect = 2e-95
Identities = 239/662 (36%), Positives = 361/662 (54%), Gaps = 77/662 (11%)
Query: 587 LLYQAASPDEGALVTAARNFGYVFLSRTQDTVTI--MELGEERVYQVLAIMDFNSTRKRM 644
L Y+A SPDE ALV AAR + SRT + V + LG +Q+L I+ F+S RKRM
Sbjct: 721 LCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGP-LTFQLLHILPFDSVRKRM 779
Query: 645 SVLVRKP-EGAICLYTKGADTVIFERLH-----------RRGAMEFATEEALAAFAQETL 692
SV+VR P + +YTKGAD+VI E L ++ + T++ L +A++ L
Sbjct: 780 SVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGL 839
Query: 693 RTLCLAYREVAEDIYEDWQQRHQEASLLLQNRAQALQQ----------LLGATAIEDRLQ 742
RTLC+A + +++ Y +W + H A + NR + L + LLGAT IEDRLQ
Sbjct: 840 RTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQ 899
Query: 743 DGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWEN 802
+GVPE+I+ L K+ IKIW+LTGDKQETAVNI +AC+LL + + IL T ++
Sbjct: 900 EGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLF-------ILNTQSKD 952
Query: 803 SNNLLTRESLSQVKLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLY 862
+ +L + +L L+K+ +AL + V++ E + R L
Sbjct: 953 ACGML------------------MSTILKELQKKTQALPEQVSLSEDLLQPPVPRDSGL- 993
Query: 863 ARRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALI 922
R GL + + + E LQ++ F++L S CQAV+CCR TP QK+ +
Sbjct: 994 ---------RAGLIITGKTLEFAL----QESLQKQ-FLELTSWCQAVVCCRATPLQKSEV 1039
Query: 923 VALVKKYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLL 982
V LV+ + QV+TLAIGDGAND++MI+ AD+G+G++GQEGMQAV SDF + QF L +LL
Sbjct: 1040 VKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLL 1099
Query: 983 LVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLP 1042
LVHG W Y R+ + YFFYK++A + + W+ + GF+G + + W L FNLL+++ P
Sbjct: 1100 LVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAP 1159
Query: 1043 VLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISR 1102
+ G+ E+DVSAE ++ PELY GQK E + F + SLV FF+ + +
Sbjct: 1160 PVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQ 1219
Query: 1103 DTAGPASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQ 1162
S +D +F + + L + + +++ K T + + I+ S+ Y +
Sbjct: 1220 -----GSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYFLFAIVFG 1274
Query: 1163 SFWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLALRV----IFPALKELR 1218
+ + +P + P+ + M P LV +L+ SI P RV +FP+ LR
Sbjct: 1275 AMCV-TCNPPSNPY-WIMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQGSLFPS-PILR 1331
Query: 1219 AK 1220
AK
Sbjct: 1332 AK 1333
Score = 273 bits (698), Expect = 8e-73
Identities = 147/397 (37%), Positives = 233/397 (58%), Gaps = 7/397 (1%)
Query: 133 YKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMVCL 192
Y N IRT KY +F+P NL+EQFHR +NL+FL +++L +P + P+V +
Sbjct: 71 YVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVV 130
Query: 193 LFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFK--QKKWQDLCVGDVVCLRKDNIVP 250
L I A +D ++D ++K D+ INN ++ K K + W+D+ VGD + L + ++P
Sbjct: 131 LTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVIP 190
Query: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
ADM+LL ST+P +C++ET +DGE+NLK RQ + ++ + + F + CE+PN
Sbjct: 191 ADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDP-EKFSSRIECESPN 249
Query: 311 SRMHHFVGCLEWNDK-KYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKIHL 369
+ + F G LE ++K + L NLLLRGC IRNT+ G+V+YAG +TK M N
Sbjct: 250 NDLSRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRY 309
Query: 370 KRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYL---SGVHGSSVAAES 426
KR+KL+ N V+ + +V++CL A G G + ++ H++ H S
Sbjct: 310 KRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMHFFNVPEPDGHIISPLLAG 369
Query: 427 FFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHL 486
F++FW+ +ILL V IP+S+++ E + LG FI DV Y + D + R+ ++ + L
Sbjct: 370 FYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDL 429
Query: 487 GQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEA 523
GQ++Y+FSDKTGTLT+N + F +C ++G Y + A
Sbjct: 430 GQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENA 466
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 338 bits (868), Expect = 2e-92
Identities = 227/677 (33%), Positives = 354/677 (52%), Gaps = 80/677 (11%)
Query: 586 QLLYQAASPDEGALVTAARNFGYVFLSRTQDTVTI-MELGEERVYQVLAIMDFNSTRKRM 644
+ Y+A SPDE ALV AA + + +SRT + VT+ + G + +L + F+S RKRM
Sbjct: 714 EFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRM 773
Query: 645 SVLVRKP-EGAICLYTKGADTVIFERLH------------RRGAMEFATEEALAAFAQET 691
SV+VR P G I +YTKGAD+VI + L + + T++ L +A++
Sbjct: 774 SVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDG 833
Query: 692 LRTLCLAYREVAEDIYEDWQQRHQEASLLLQNRAQALQQ----------LLGATAIEDRL 741
LRTLC+A + V+E+ + W +EA L NR + L + LLGAT IEDRL
Sbjct: 834 LRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRL 893
Query: 742 QDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWE 801
Q+GVP+TI L+++ I++WVLTGDKQETAVNI +C LL++ + Y
Sbjct: 894 QEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTV------------YTI 941
Query: 802 NSNNLLTRESLSQVKLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFL 861
N+ N T ES+ L + K L+K R L F
Sbjct: 942 NTENQETCESILNCALEEL-------KQFRELQKPDRKLF-----------------GFR 977
Query: 862 YARRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKAL 921
+ + +P A + E+ F++L C++V+CCR TP QK++
Sbjct: 978 LPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSM 1037
Query: 922 IVALVKKYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRL 981
IV LV+ +V+TL+IGDGAND++MI+ AD+G+G++GQEGMQAV +SDF + +F L++L
Sbjct: 1038 IVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKL 1097
Query: 982 LLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTL 1041
LLVHG W Y R+ + + Y+ YK++ + + W+ + GF+ + + W + FNL +++L
Sbjct: 1098 LLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSL 1157
Query: 1042 PVLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWIS 1101
P L G+ ++D+SAE L PELY GQ E +N F ++ SL+ FF+
Sbjct: 1158 PPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPY--- 1214
Query: 1102 RDTAGPASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTT 1161
A S D +F + L +I + + +K WT +L S Y +++
Sbjct: 1215 --LAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLY 1272
Query: 1162 QSFWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLAL--RVIFPAL----- 1214
+ + SPT P+ + +S+P+ LV L+ PV+AL R F +L
Sbjct: 1273 NATCVICNSPTN-PYWVME-GQLSNPTFYLVCFLT------PVVALLPRYFFLSLQGTCG 1324
Query: 1215 KELRAKEEKVEEGPSEE 1231
K L +K +K+++ P ++
Sbjct: 1325 KSLISKAQKIDKLPPDK 1341
Score = 265 bits (677), Expect = 2e-70
Identities = 149/407 (36%), Positives = 238/407 (58%), Gaps = 9/407 (2%)
Query: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
++Y N T KY ++FLP NL+EQFHR +NL+FL ++IL +P + P+
Sbjct: 64 RRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLA 123
Query: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGK--SFKQKKWQDLCVGDVVCLRKDNI 248
+LF+ +D ++D RH+ D+AIN +I K ++ QK W+D+ VGD + ++ + I
Sbjct: 124 IVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEI 183
Query: 249 VPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEA 308
VPAD+LLL S++P+ +C++ET +DGETNLK R + ++ + F T+ CE
Sbjct: 184 VPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPEL-FHNTIVCEK 242
Query: 309 PNSRMHHFVGCLEWNDK-KYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKI 367
PN+ ++ F G +E D+ + +LLLRGC IRNT+ G+VIYAG +TK M N
Sbjct: 243 PNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGP 302
Query: 368 HLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYY-LSGVHGSSV--AA 424
KR+K++ MN + ++L+CL+ A G F++H + + +GS + A
Sbjct: 303 RYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSAL 362
Query: 425 ESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLND 484
F++F + +ILL V IP+S+++ E + LG F+ D+ +Y + D+ + R+ ++ +
Sbjct: 363 GGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAE 422
Query: 485 HLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEA--TTRPKE 529
LGQ++YIFSDKTGTLT+N + F +C I G Y A PKE
Sbjct: 423 DLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKE 469
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 337 bits (863), Expect = 6e-92
Identities = 301/1124 (26%), Positives = 515/1124 (45%), Gaps = 162/1124 (14%)
Query: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
+K+ N I+ KYN ++F+P LYEQF NL+FL+I Q +P + ++ P+
Sbjct: 128 EKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLG 187
Query: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
+L + TR+ +D+ R + D+ +N++ L + Q K D+ VGD++ + K+ +P
Sbjct: 188 FVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIP 247
Query: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
+DM+ L ++E + C++ T +DGET+ K + A+ T ++L + + S V + P
Sbjct: 248 SDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCT-QQLPALGDLFSISAYVYAQKPQ 306
Query: 311 SRMHHFVGCLEWNDKK----YSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGK 366
+H F G D SL I N L + + T G+VIY G +T+ + N
Sbjct: 307 MDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVAS-GTVIGVVIYTGKETRSVMNTSN 365
Query: 367 IHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAES 426
K LDL +N+L +F+++V + +V+ GF +++
Sbjct: 366 PKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRN----------------- 408
Query: 427 FFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKA-RSTSLNDH 485
+ FL+L S IP+S+ + + +G +V+ W M K +++P R++++ +
Sbjct: 409 ---LFRFLLLFSYIIPISLRVNLD---MGKAVY-GW---MMMKDENIPGTVVRTSTIPEE 458
Query: 486 LGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDS--EATTRPKENPYLWNKFADGKL- 542
LG++ Y+ +DKTGTLTQN + F + + YG D+ E + +++ A G
Sbjct: 459 LGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNT 518
Query: 543 ----LFHNAALLHLVRTNGDEAVREFWRLLAICHTV---------MVRESPRERPDQ--- 586
L + VR + + E + + +CH V + E+ DQ
Sbjct: 519 GSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFS 578
Query: 587 ---LLYQAASPDEGALVTAARNFGYVFLSRTQDTVTIMEL----GEERVYQVLAIMDFNS 639
YQA+SPDE ALV + G +SR +T M+L G+ + +L + F S
Sbjct: 579 DENRTYQASSPDEVALVQWTESVGLTLVSRD---LTSMQLKTPSGQVLSFCILQLFPFTS 635
Query: 640 TRKRMSVLVRKPEGA-ICLYTKGADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLA 698
KRM V+VR A I Y KGAD + + +E E A+E LRTL +A
Sbjct: 636 ESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLE----EECGNMAREGLRTLVVA 691
Query: 699 YREVAEDIYEDWQQRHQEASLLLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIK 758
+ + E+ Y+D++ R+ +A L + +R+ L A+ + L+ ++
Sbjct: 692 KKALTEEQYQDFESRYTQAKLSMHDRS------LKVAAVVESLE------------REME 733
Query: 759 IWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENSNNLLTRESLSQVKLA 818
+ LTG + + ++ E+L + + W +LT + L
Sbjct: 734 LLCLTGVEDQLQADVRPTLEMLRNAGIKI------------W-----MLTGDKLETATCI 776
Query: 819 LVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLS----LLCRRFG 874
+ LVS ++ Q + EA EL RR A +S +C ++
Sbjct: 777 AKSSH------LVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKY- 829
Query: 875 LPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVT 934
E FV+LA +C AV+CCR +P QKA IV L++++ T
Sbjct: 830 --------------------YEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRT 869
Query: 935 LAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRIC 994
AIGDG ND++MI+ AD G+G+ G+EG QA +DF + QF + RLL+VHGR SY R
Sbjct: 870 CAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSA 929
Query: 995 KFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVS 1054
++ ++ + +Q F+ F PLY+G+ + + +Y+ PV + + +QDV
Sbjct: 930 ALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVK 988
Query: 1055 AEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISRDTAGPASFSD-- 1112
E ++ PELY KD + G + S F + + IS G +
Sbjct: 989 PEMAMLYPELY----KD-----------LTKGRSLSFKTFLIWVLISIYQGGILMYGALV 1033
Query: 1113 --HQSFAVVVALSCLLSITMEVILI---IKYWTALCVATILLSLGFY-AIMTTTTQSFWL 1166
F VVA+S I E++++ ++ W L V LSLG Y + + + F +
Sbjct: 1034 LFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGI 1093
Query: 1167 FRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLALRVI 1210
RVS F D++ +++ + L V ++ P+ L+ +
Sbjct: 1094 GRVSFGAF----LDVAFITTVTFLWKVSAITVVSCLPLYVLKYL 1133
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 335 bits (858), Expect = 2e-91
Identities = 298/1113 (26%), Positives = 511/1113 (45%), Gaps = 163/1113 (14%)
Query: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
++Y NVI KYNF++FLP L+ QF NL+FL++ Q +P++ ++ P+
Sbjct: 51 QRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLG 110
Query: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
+L + R+ V+++ + D+ +N++ L + + K ++ VGD++ + K+ VP
Sbjct: 111 FVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVP 170
Query: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
ADM+ L ++E + C++ T +DGET+ K R + T + L T + + V E PN
Sbjct: 171 ADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQR-LPTAADLLQIRSYVYAEEPN 229
Query: 311 SRMHHFVGCLEWNDK----KYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGK 366
+H+FVG D SL I N L G + + T G+V+Y G + + + N
Sbjct: 230 IDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVA-SGTVVGVVLYTGRELRSVMNTSN 288
Query: 367 IHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAES 426
K DL +N L ++F ++V+V LV+ +++ F +YL +
Sbjct: 289 PRSKIGLFDLEVNCLTKILFGALVVVSLVMV-----ALQHFAG-RWYLQIIR-------- 334
Query: 427 FFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAK-ARSTSLNDH 485
FL+L S IP+S+ + + +G V+ W ++ + +P RS+++ +
Sbjct: 335 ------FLLLFSNIIPISLRVNLD---MGKIVY-SWVIR---RDSKIPGTVVRSSTIPEQ 381
Query: 486 LGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFH 545
LG++ Y+ +DKTGTLTQN + F + + YG DS + ++ + +
Sbjct: 382 LGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQ-SHIFSIYTQQSQDPPAQK 440
Query: 546 NAALLHLVRTNGDEAVREFWRLLAICHTVM----------VRESPRERPDQL-LYQAASP 594
L VR V E + +A+CH V E+ ++ D +YQA+SP
Sbjct: 441 GPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDSCRVYQASSP 500
Query: 595 DEGALVTAARNFGYVFLSRTQDTVTIMELGEERV-YQVLAIMDFNSTRKRMSVLVR-KPE 652
DE ALV + G + R Q ++ + G++ + + +L I F KRM ++VR +
Sbjct: 501 DEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRMGIIVRDEST 560
Query: 653 GAICLYTKGADTVIFERLHRRGAMEFA--TEEALAAFAQETLRTLCLAYREVAEDIYEDW 710
G I Y KGAD V+ G +++ EE A+E LR L +A + +AE+ Y+D+
Sbjct: 561 GEITFYMKGADVVM------AGIVQYNDWLEEECGNMAREGLRVLVVAKKSLAEEQYQDF 614
Query: 711 QQRHQEASLLLQNRA----------QALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIW 760
+ R+ +A L + +R+ + +LL T +ED+LQ V T++ L+ + IK+W
Sbjct: 615 EARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVW 674
Query: 761 VLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALV 820
+LTGDK ETA L++ N I + ++ E + E N R+ ALV
Sbjct: 675 MLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLE--LNAFRRKH----DCALV 728
Query: 821 INGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAP 880
I+GD L+ L E LA + +++C R
Sbjct: 729 ISGDSLEVCLKYYEYEFMELA---------------------CQCPAVVCCR------CA 761
Query: 881 PAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDG 940
P Q ++ R +LQER + C V GDG
Sbjct: 762 PTQKAQIVR---LLQERT---------GKLTCAV-----------------------GDG 786
Query: 941 ANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYF 1000
ND++MI+ +D GVG+ G+EG QA +DF + QF L RLL+VHGR SY R ++
Sbjct: 787 GNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFV 846
Query: 1001 FYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLE 1060
++S+ +Q F+ F PLY+G+ + ++ +Y+ PV + + ++DV +E ++
Sbjct: 847 IHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAML 905
Query: 1061 KPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSFAVVV 1120
PELY K +Y F L+ ++++ A F +V
Sbjct: 906 YPELYKDLLKGRPLSYKTF-----------LIWVLISIYQGSTIMYGALLLFESEFVHIV 954
Query: 1121 AL---SCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFL 1177
A+ S +L+ + V L I+ W L LLSL Y ++ F
Sbjct: 955 AISFTSLILTELLMVALTIQTWHWLMTVAELLSLACY--------------IASLVFLHE 1000
Query: 1178 YADLSVMSSPSILLVVLLSVSINTFPVLALRVI 1210
+ D+ +++ S L V + ++ P+ L+ +
Sbjct: 1001 FIDVYFIATLSFLWKVSVITLVSCLPLYVLKYL 1033
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 330 bits (847), Expect = 4e-90
Identities = 224/636 (35%), Positives = 331/636 (52%), Gaps = 99/636 (15%)
Query: 553 VRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYVFLS 612
+ +NG + + W + + +E ER +L Y+A SPDE ALV AAR + V +
Sbjct: 665 IASNGYSSQADNWA------SELAQEQESER--ELRYEAESPDEAALVYAARAYNCVLVE 716
Query: 613 RTQDTVTIM--ELGEERVYQVLAIMDFNSTRKRMSVLVRKP-EGAICLYTKGADTVIFER 669
R D V++ LG +++L + F+S RKRMSV++R P I +YTKGAD+V+ +
Sbjct: 717 RLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDL 775
Query: 670 LHRRGAMEFA----------TEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASL 719
L +++ T+ L +A E LRTLC+A R ++++ Y W Q H EA
Sbjct: 776 LQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAES 835
Query: 720 LLQNRAQALQQ----------LLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQET 769
L+N + L Q LLGAT IEDRLQDGVPETI L+++ ++IWVLTGDKQET
Sbjct: 836 SLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQET 895
Query: 770 AVNIGFACELLSENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALVINGDFLDKL 829
AVNI +AC+LL ++ ++T + SQ A +++
Sbjct: 896 AVNIAYACKLL--------------------DHDEEVITLNATSQEACAALLDQCLCYVQ 935
Query: 830 LVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDSRARR 889
L++ P V+M R S LC P + RR
Sbjct: 936 SRGLQRAPEKTKGKVSM------------------RFSSLC--------PPSTSTASGRR 969
Query: 890 SSEVLQERA------------FVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAI 937
S V+ R+ F+ LA +C++V+CCR TP QK+++V LV+ + +TLAI
Sbjct: 970 PSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAI 1029
Query: 938 GDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFL 997
GDGAND++MI+ ADVGVG++GQEGMQAV SDF + +F +L+RLL++HG W Y R+ +
Sbjct: 1030 GDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMV 1089
Query: 998 RYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQ 1057
YFFYK+ + + WF + GF+ + + W+L FNLL+S+LP L G+ ++DV A
Sbjct: 1090 LYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANV 1149
Query: 1058 SLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSFA 1117
L P+LY GQ E + F +A SLV F + D S D ++
Sbjct: 1150 LLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYD-----SNVDLFTWG 1204
Query: 1118 VVVALSCLLSITMEVILIIKYWTAL----CVATILL 1149
+ LL+ + + + K WT L C ++LL
Sbjct: 1205 TPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLL 1240
Score = 273 bits (699), Expect = 6e-73
Identities = 152/395 (38%), Positives = 235/395 (59%), Gaps = 8/395 (2%)
Query: 136 NVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMVCLLFI 195
N ++T KY SFLP NL+EQFHR +N++F+ I +L +P ++ P++ +L I
Sbjct: 62 NRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAI 121
Query: 196 RATRDLVDDMGRHKSDRAINNRPCQILMG--KSFKQKKWQDLCVGDVVCLRKDNIVPADM 253
A RDL +D RH+SD IN+ C + K + + W+++ VGD V LR + I PAD+
Sbjct: 122 TAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADI 181
Query: 254 LLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPNSRM 313
LLL+S++P LC++ET ++DGETNLK RQ + EL + +F + CE PN+ +
Sbjct: 182 LLLSSSDPDGLCHIETANLDGETNLKRRQVVR-GFSELVSEFNPLTFTSVIECEKPNNDL 240
Query: 314 HHFVGCL-EWNDKKYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKIHLKRT 372
F GC+ N KK L NLLLRGC +RNTD G+VIYAG +TK + N KR+
Sbjct: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
Query: 373 KLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHH--YYLSGVHGSSVA--AESFF 428
KL+ MN V+ + +V + L A G G + +++ +Y+ GSS++ + +
Sbjct: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
Query: 429 VFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQ 488
F + +I+L V IP+S+++ E + FI+ D+Q+Y + D + R+ ++ + LGQ
Sbjct: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
Query: 489 VEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEA 523
++YIFSDKTGTLT+N + F +C +SG Y D+ A
Sbjct: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANA 455
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 301 bits (772), Expect = 2e-81
Identities = 151/342 (44%), Positives = 220/342 (64%), Gaps = 14/342 (4%)
Query: 108 KVQANNRAYNGQFKEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLI 167
+ +AN+R YN +F+ Y +N I+T+KYN +FLP+NL+EQF V+N +FL
Sbjct: 15 RARANDREYNEKFQ-----------YASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLF 63
Query: 168 IIILQSIPDISTLPWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSF 227
++ILQ IP IS+L WF+ P+V +L I A +D DD RHKSD +NNR Q+L+
Sbjct: 64 LLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGIL 123
Query: 228 KQKKWQDLCVGDVVCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVT 287
+Q++W ++CVGD++ L + V AD+LLL+S+EP LCY+ET ++DGETN+K RQA+ VT
Sbjct: 124 QQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVT 183
Query: 288 HKELATIKKMASFQGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRNTDTC 347
EL I K+A F G V CE PN+++ F G L W + K+ L N+LLRGC +RNT+ C
Sbjct: 184 -SELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWC 242
Query: 348 YGLVIYAGFDTKIMKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKE- 406
+GLVI+AG DTK+M+N G+ KRT +D LMN LV+ IF +V + ++LA G E
Sbjct: 243 FGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEV 302
Query: 407 -FKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSMFI 447
+ Y S F FWS++I+L+ +P+S+++
Sbjct: 303 GMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYV 344
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 90.5 bits (223), Expect = 9e-18
Identities = 103/412 (25%), Positives = 177/412 (42%), Gaps = 72/412 (17%)
Query: 433 FLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQVEYI 492
F+ + I + + + E + L ++ + + V+ K ++ R + +G I
Sbjct: 406 FVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL---VRHLDACETMGNATAI 462
Query: 493 FSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFHNAALLHL 552
SDKTGTLT N +T + I G Y P + +L +L L
Sbjct: 463 CSDKTGTLTMNRMTVVQAYIGGIHY------RQIPSPDVFL-------------PKVLDL 503
Query: 553 VRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYVFLS 612
+ NG ++I + P E+ L Q + E AL+ G+V
Sbjct: 504 I-VNG----------ISINSAYTSKILPPEKEGGLPRQVGNKTECALL------GFVTDL 546
Query: 613 RTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTVIFER--- 669
+ E+ EE++Y+V FNS RK MS ++R P G +Y+KGA +I +
Sbjct: 547 KQDYQAVRNEVPEEKLYKVYT---FNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNR 603
Query: 670 -LHRRG-AMEFATEE-------ALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLL 720
L R+G A+ F ++ + A + LRT+C+AYR+ +D W ++ + L
Sbjct: 604 ILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDF-DDTEPSWDNENEILTEL 662
Query: 721 LQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELL 780
+ IED ++ VP+ I K++ I + ++TGD TA I C +L
Sbjct: 663 ---------TCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGIL 713
Query: 781 S--ENMLILEEKEISRILETYWENSNNLLTRESLSQV--KLALVINGDFLDK 828
+ ++ L LE KE +R++ N + +E L ++ KL ++ DK
Sbjct: 714 TPGDDFLCLEGKEFNRLI----RNEKGEVEQEKLDKIWPKLRVLARSSPTDK 761
Score = 41.2 bits (95), Expect = 0.007
Identities = 34/101 (33%), Positives = 55/101 (54%), Gaps = 6/101 (5%)
Query: 919 KALIVALVKKYHQVVTLAIGDGANDINMIKTADVG--VGLAGQEGMQAVQNSDFVLGQFC 976
K +I + V ++ QVV + GDG ND +K ADVG +G+AG + A + SD +L
Sbjct: 766 KGIIDSTVGEHRQVVAVT-GDGTNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDN 822
Query: 977 FLQRL-LLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFAC 1016
F + ++ GR Y I KFL++ ++ +++V AC
Sbjct: 823 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 863
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 90.5 bits (223), Expect = 9e-18
Identities = 103/412 (25%), Positives = 177/412 (42%), Gaps = 72/412 (17%)
Query: 433 FLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQVEYI 492
F+ + I + + + E + L ++ + + V+ K ++ R + +G I
Sbjct: 406 FVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL---VRHLDACETMGNATAI 462
Query: 493 FSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFHNAALLHL 552
SDKTGTLT N +T + I G Y P + +L +L L
Sbjct: 463 CSDKTGTLTMNRMTVVQAYIGGIHY------RQIPSPDVFL-------------PKVLDL 503
Query: 553 VRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYVFLS 612
+ NG ++I + P E+ L Q + E AL+ G+V
Sbjct: 504 I-VNG----------ISINSAYTSKILPPEKEGGLPRQVGNKTECALL------GFVTDL 546
Query: 613 RTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTVIFER--- 669
+ E+ EE++Y+V FNS RK MS ++R P G +Y+KGA +I +
Sbjct: 547 KQDYQAVRNEVPEEKLYKVYT---FNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNR 603
Query: 670 -LHRRG-AMEFATEE-------ALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLL 720
L R+G A+ F ++ + A + LRT+C+AYR+ +D W ++ + L
Sbjct: 604 ILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDF-DDTEPSWDNENEILTEL 662
Query: 721 LQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELL 780
+ IED ++ VP+ I K++ I + ++TGD TA I C +L
Sbjct: 663 ---------TCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGIL 713
Query: 781 S--ENMLILEEKEISRILETYWENSNNLLTRESLSQV--KLALVINGDFLDK 828
+ ++ L LE KE +R++ N + +E L ++ KL ++ DK
Sbjct: 714 TPGDDFLCLEGKEFNRLI----RNEKGEVEQEKLDKIWPKLRVLARSSPTDK 761
Score = 41.2 bits (95), Expect = 0.007
Identities = 34/101 (33%), Positives = 55/101 (54%), Gaps = 6/101 (5%)
Query: 919 KALIVALVKKYHQVVTLAIGDGANDINMIKTADVG--VGLAGQEGMQAVQNSDFVLGQFC 976
K +I + V ++ QVV + GDG ND +K ADVG +G+AG + A + SD +L
Sbjct: 766 KGIIDSTVGEHRQVVAVT-GDGTNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDN 822
Query: 977 FLQRL-LLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFAC 1016
F + ++ GR Y I KFL++ ++ +++V AC
Sbjct: 823 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 863
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 87.8 bits (216), Expect = 6e-17
Identities = 113/479 (23%), Positives = 199/479 (41%), Gaps = 91/479 (18%)
Query: 370 KRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESFFV 429
K TKL + + K +V+ ++ ++ LVL F V V G + AE V
Sbjct: 363 KLTKLAVQIGKAGLVMS-AITVIILVLYFVIETFV------------VEGRTWLAECTPV 409
Query: 430 FWSFLI-LLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQ 488
+ + + + + + + + E + L ++ + + V+ K ++ R + +G
Sbjct: 410 YVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL---VRHLDACETMGN 466
Query: 489 VEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPY---LWNKFADGKLLFH 545
I SDKTGTLT N +T + + Y KE P L K D
Sbjct: 467 ATAICSDKTGTLTTNRMTVVQSYLGDTHY----------KEIPAPSALTPKILD------ 510
Query: 546 NAALLHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARN 605
L+H + N +T + P E+ L Q + E AL+
Sbjct: 511 --LLVHAISINS-------------AYTTKIL--PPEKEGALPRQVGNKTECALL----- 548
Query: 606 FGYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTV 665
G+V + ++ E+++Y+V FNS RK MS ++R P+G L++KGA +
Sbjct: 549 -GFVLDLKRDFQPVREQIPEDKLYKVYT---FNSVRKSMSTVIRMPDGGFRLFSKGASEI 604
Query: 666 IFER----LHRRGAM--------EFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQR 713
+ ++ L+ G + + + + A + LRT+C+AYR+ + DW
Sbjct: 605 LLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNE 664
Query: 714 HQEASLLLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNI 773
++ L + IED ++ VPE I+ +++ I + ++TGD TA I
Sbjct: 665 NEVVGDL---------TCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAI 715
Query: 774 GFACELL--SENMLILEEKEISRILETYWENSNNLLTRESLSQV--KLALVINGDFLDK 828
C ++ E+ L LE KE +R + N + +E L +V KL ++ DK
Sbjct: 716 AAKCGIIQPGEDFLCLEGKEFNRRI----RNEKGEIEQERLDKVWPKLRVLARSSPTDK 770
Score = 38.5 bits (88), Expect = 0.042
Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Query: 919 KALIVALVKKYHQVVTLAIGDGANDINMIKTADVG--VGLAGQEGMQAVQNSDFVLGQFC 976
K +I + + QVV + GDG ND +K ADVG +G+AG + A + SD +L
Sbjct: 775 KGIIDSTTGEQRQVVAVT-GDGTNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDN 831
Query: 977 FLQRL-LLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFAC 1016
F + ++ GR Y I KFL++ ++ +++V AC
Sbjct: 832 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 872
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 87.8 bits (216), Expect = 6e-17
Identities = 113/479 (23%), Positives = 199/479 (41%), Gaps = 91/479 (18%)
Query: 370 KRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESFFV 429
K TKL + + K +V+ ++ ++ LVL F V V G + AE V
Sbjct: 363 KLTKLAVQIGKAGLVMS-AITVIILVLYFVIETFV------------VEGRTWLAECTPV 409
Query: 430 FWSFLI-LLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQ 488
+ + + + + + + + E + L ++ + + V+ K ++ R + +G
Sbjct: 410 YVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL---VRHLDACETMGN 466
Query: 489 VEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPY---LWNKFADGKLLFH 545
I SDKTGTLT N +T + + Y KE P L K D
Sbjct: 467 ATAICSDKTGTLTTNRMTVVQSYLGDTHY----------KEIPAPSALTPKILD------ 510
Query: 546 NAALLHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARN 605
L+H + N +T + P E+ L Q + E AL+
Sbjct: 511 --LLVHAISINS-------------AYTTKIL--PPEKEGALPRQVGNKTECALL----- 548
Query: 606 FGYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTV 665
G+V + ++ E+++Y+V FNS RK MS ++R P+G L++KGA +
Sbjct: 549 -GFVLDLKRDFQPVREQIPEDKLYKVYT---FNSVRKSMSTVIRMPDGGFRLFSKGASEI 604
Query: 666 IFER----LHRRGAM--------EFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQR 713
+ ++ L+ G + + + + A + LRT+C+AYR+ + DW
Sbjct: 605 LLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNE 664
Query: 714 HQEASLLLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNI 773
++ L + IED ++ VPE I+ +++ I + ++TGD TA I
Sbjct: 665 NEVVGDL---------TCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAI 715
Query: 774 GFACELL--SENMLILEEKEISRILETYWENSNNLLTRESLSQV--KLALVINGDFLDK 828
C ++ E+ L LE KE +R + N + +E L +V KL ++ DK
Sbjct: 716 AAKCGIIQPGEDFLCLEGKEFNRRI----RNEKGEIEQERLDKVWPKLRVLARSSPTDK 770
Score = 38.5 bits (88), Expect = 0.042
Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Query: 919 KALIVALVKKYHQVVTLAIGDGANDINMIKTADVG--VGLAGQEGMQAVQNSDFVLGQFC 976
K +I + + QVV + GDG ND +K ADVG +G+AG + A + SD +L
Sbjct: 775 KGIIDSTTGEQRQVVAVT-GDGTNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDN 831
Query: 977 FLQRL-LLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFAC 1016
F + ++ GR Y I KFL++ ++ +++V AC
Sbjct: 832 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 872
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
sapiens]
Length = 1198
Score = 81.6 bits (200), Expect = 4e-15
Identities = 96/417 (23%), Positives = 170/417 (40%), Gaps = 81/417 (19%)
Query: 433 FLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQVEYI 492
F+ + + + + + E + L ++ + + V+ K ++ R + +G I
Sbjct: 395 FVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL---VRHLDACETMGNATAI 451
Query: 493 FSDKTGTLTQNILTFNKCCISGRVYG--PD-SEATTRPKENPYLWNKFADGKLLFHNAAL 549
SDKTGTLT N +T + + Y PD S T+ E L NA
Sbjct: 452 CSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTME-------------LLINA-- 496
Query: 550 LHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYV 609
+AI + P E+ L Q + E L+ G+V
Sbjct: 497 ------------------IAINSAYTTKILPPEKEGALPRQVGNKTECGLL------GFV 532
Query: 610 FLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTVIFE- 668
+ ++ EE++Y+V FNS RK MS +++ P+ + +Y+KGA ++ +
Sbjct: 533 LDLKQDYEPVRSQMPEEKLYKVYT---FNSVRKSMSTVIKLPDESFRMYSKGASEIVLKK 589
Query: 669 -----------RLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEA 717
R+ R + ++ + A + LRT+C+AYR+ DW
Sbjct: 590 CCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDW------- 642
Query: 718 SLLLQNRAQALQQL--LGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGF 775
N L +L + IED ++ VPE I+ +++ I + ++TGD TA I
Sbjct: 643 ----DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAI 698
Query: 776 ACELL--SENMLILEEKEISRILETYWENSNNLLTRESLSQV--KLALVINGDFLDK 828
C ++ E+ L LE KE +R + N + +E + ++ KL ++ DK
Sbjct: 699 KCGIIHPGEDFLCLEGKEFNRRI----RNEKGEIEQERIDKIWPKLRVLARSSPTDK 751
Score = 37.7 bits (86), Expect = 0.072
Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 11/115 (9%)
Query: 910 ICCRVTPKQK-ALIVALVKKYH----QVVTLAIGDGANDINMIKTADVG--VGLAGQEGM 962
+ R +P K L+ ++ H QVV + GDG ND +K ADVG +G+AG +
Sbjct: 742 VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVT-GDGTNDGPALKKADVGFAMGIAGTD-- 798
Query: 963 QAVQNSDFVLGQFCFLQRL-LLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFAC 1016
A + SD +L F + ++ GR Y I KFL++ ++ +++V AC
Sbjct: 799 VAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 853
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
sapiens]
Length = 1243
Score = 81.6 bits (200), Expect = 4e-15
Identities = 96/417 (23%), Positives = 170/417 (40%), Gaps = 81/417 (19%)
Query: 433 FLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQVEYI 492
F+ + + + + + E + L ++ + + V+ K ++ R + +G I
Sbjct: 440 FVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL---VRHLDACETMGNATAI 496
Query: 493 FSDKTGTLTQNILTFNKCCISGRVYG--PD-SEATTRPKENPYLWNKFADGKLLFHNAAL 549
SDKTGTLT N +T + + Y PD S T+ E L NA
Sbjct: 497 CSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTME-------------LLINA-- 541
Query: 550 LHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYV 609
+AI + P E+ L Q + E L+ G+V
Sbjct: 542 ------------------IAINSAYTTKILPPEKEGALPRQVGNKTECGLL------GFV 577
Query: 610 FLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTVIFE- 668
+ ++ EE++Y+V FNS RK MS +++ P+ + +Y+KGA ++ +
Sbjct: 578 LDLKQDYEPVRSQMPEEKLYKVYT---FNSVRKSMSTVIKLPDESFRMYSKGASEIVLKK 634
Query: 669 -----------RLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEA 717
R+ R + ++ + A + LRT+C+AYR+ DW
Sbjct: 635 CCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDW------- 687
Query: 718 SLLLQNRAQALQQL--LGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGF 775
N L +L + IED ++ VPE I+ +++ I + ++TGD TA I
Sbjct: 688 ----DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAI 743
Query: 776 ACELL--SENMLILEEKEISRILETYWENSNNLLTRESLSQV--KLALVINGDFLDK 828
C ++ E+ L LE KE +R + N + +E + ++ KL ++ DK
Sbjct: 744 KCGIIHPGEDFLCLEGKEFNRRI----RNEKGEIEQERIDKIWPKLRVLARSSPTDK 796
Score = 37.7 bits (86), Expect = 0.072
Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 11/115 (9%)
Query: 910 ICCRVTPKQK-ALIVALVKKYH----QVVTLAIGDGANDINMIKTADVG--VGLAGQEGM 962
+ R +P K L+ ++ H QVV + GDG ND +K ADVG +G+AG +
Sbjct: 787 VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVT-GDGTNDGPALKKADVGFAMGIAGTD-- 843
Query: 963 QAVQNSDFVLGQFCFLQRL-LLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFAC 1016
A + SD +L F + ++ GR Y I KFL++ ++ +++V AC
Sbjct: 844 VAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 898
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 72.4 bits (176), Expect = 3e-12
Identities = 91/413 (22%), Positives = 168/413 (40%), Gaps = 72/413 (17%)
Query: 433 FLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQVEYI 492
F+ + + + + + E + L ++ + + V+ K ++ R + +G I
Sbjct: 416 FVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL---VRHLDACETMGNATAI 472
Query: 493 FSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFHNAALLHL 552
SDKTGTLT N +T + I+ + Y E P P + + G
Sbjct: 473 CSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIP---PNILSYLVTG------------ 517
Query: 553 VRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYVFLS 612
+++ + P E+ L + E AL+ + L
Sbjct: 518 ---------------ISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLLD-----LK 557
Query: 613 RTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTVIFE---- 668
R V E+ EE +Y+V FNS RK MS +++ +G+ +++KGA +I +
Sbjct: 558 RDYQDVR-NEIPEEALYKVYT---FNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFK 613
Query: 669 --------RLHRRGAMEFATEEALAAFAQETLRTLCLAYREV-AEDIYEDWQQRHQEASL 719
++ R + + + A E LRT+CLA+R+ A + +W + +
Sbjct: 614 ILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTG 673
Query: 720 LLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACEL 779
L + IED ++ VP+ IK +++ I + ++TGD TA I C +
Sbjct: 674 L---------TCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGI 724
Query: 780 L--SENMLILEEKEISRILETYWENSNNLLTRESLSQV--KLALVINGDFLDK 828
L E+ L LE K+ +R + N + +E + ++ KL ++ DK
Sbjct: 725 LHPGEDFLCLEGKDFNRRI----RNEKGEIEQERIDKIWPKLRVLARSSPTDK 773
Score = 40.0 bits (92), Expect = 0.015
Identities = 34/101 (33%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Query: 919 KALIVALVKKYHQVVTLAIGDGANDINMIKTADVG--VGLAGQEGMQAVQNSDFVLGQFC 976
K +I + V QVV + GDG ND +K ADVG +G+AG + A + SD +L
Sbjct: 778 KGIIDSTVSDQRQVVAVT-GDGTNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDN 834
Query: 977 FLQRL-LLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFAC 1016
F + ++ GR Y I KFL++ ++ +++V AC
Sbjct: 835 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 875
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 72.4 bits (176), Expect = 3e-12
Identities = 91/413 (22%), Positives = 168/413 (40%), Gaps = 72/413 (17%)
Query: 433 FLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQVEYI 492
F+ + + + + + E + L ++ + + V+ K ++ R + +G I
Sbjct: 416 FVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL---VRHLDACETMGNATAI 472
Query: 493 FSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFHNAALLHL 552
SDKTGTLT N +T + I+ + Y E P P + + G
Sbjct: 473 CSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIP---PNILSYLVTG------------ 517
Query: 553 VRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYVFLS 612
+++ + P E+ L + E AL+ + L
Sbjct: 518 ---------------ISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLLD-----LK 557
Query: 613 RTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTVIFE---- 668
R V E+ EE +Y+V FNS RK MS +++ +G+ +++KGA +I +
Sbjct: 558 RDYQDVR-NEIPEEALYKVYT---FNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFK 613
Query: 669 --------RLHRRGAMEFATEEALAAFAQETLRTLCLAYREV-AEDIYEDWQQRHQEASL 719
++ R + + + A E LRT+CLA+R+ A + +W + +
Sbjct: 614 ILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTG 673
Query: 720 LLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACEL 779
L + IED ++ VP+ IK +++ I + ++TGD TA I C +
Sbjct: 674 L---------TCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGI 724
Query: 780 L--SENMLILEEKEISRILETYWENSNNLLTRESLSQV--KLALVINGDFLDK 828
L E+ L LE K+ +R + N + +E + ++ KL ++ DK
Sbjct: 725 LHPGEDFLCLEGKDFNRRI----RNEKGEIEQERIDKIWPKLRVLARSSPTDK 773
Score = 40.0 bits (92), Expect = 0.015
Identities = 34/101 (33%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Query: 919 KALIVALVKKYHQVVTLAIGDGANDINMIKTADVG--VGLAGQEGMQAVQNSDFVLGQFC 976
K +I + V QVV + GDG ND +K ADVG +G+AG + A + SD +L
Sbjct: 778 KGIIDSTVSDQRQVVAVT-GDGTNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDN 834
Query: 977 FLQRL-LLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFAC 1016
F + ++ GR Y I KFL++ ++ +++V AC
Sbjct: 835 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 875
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 55.8 bits (133), Expect = 3e-07
Identities = 67/309 (21%), Positives = 133/309 (43%), Gaps = 25/309 (8%)
Query: 897 RAFVDLASKCQAVIC------CRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTA 950
R F DL+ + Q C RV P K+ IV ++ ++++ + GDG ND +K A
Sbjct: 656 REFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMT-GDGVNDAPALKKA 714
Query: 951 DVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLV-HGRWSYVRICKFLRYFFYKSMASMM 1009
++G+ + G A ++ VL F + V GR Y + +F+RY S +
Sbjct: 715 EIGIAM-GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLI-SSNVGEV 772
Query: 1010 VQVWFACYNGFTGQ--PLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVV 1067
V ++ G P+ W NL+ LP +G D+ + L +
Sbjct: 773 VCIFLTAILGLPEALIPVQLLW----VNLVTDGLPATALGFNPPDLDIMEKLPR------ 822
Query: 1068 GQKDELFNYWVFVQAIAHGVTTSLVNF-FMTLWISRDTAGP-ASFSDHQSFAVVVALSCL 1125
++ L + W+F + +A GV L T W D GP +F ++F + L
Sbjct: 823 SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPL 882
Query: 1126 LSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSVMS 1185
+ + ++ T + + ++L+++ + + +++ L R+ P P+L +++
Sbjct: 883 FAGIDCEVFESRFPTTMAL-SVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSM 941
Query: 1186 SPSILLVVL 1194
+ L++++
Sbjct: 942 ALHFLILLV 950
Score = 34.3 bits (77), Expect = 0.80
Identities = 107/481 (22%), Positives = 176/481 (36%), Gaps = 85/481 (17%)
Query: 330 DIGNLLLRGCRIRNTDTCYGLVIYAGFDT---KIMKNCGKIHLKRTKLDLLMNKLVVVIF 386
D N+L G I + G+ + G T KI + +RT L +++ +
Sbjct: 203 DKKNMLFSGTNI-TSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLS 261
Query: 387 ISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSM- 445
++ ++C+ + + ++ F D HG S + + F + L IP +
Sbjct: 262 HAISVICVAV---WVINIGHFADP------AHGGSWLRGAVYYFKIAVALAVAAIPEGLP 312
Query: 446 FILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQVEYIFSDKTGTLTQNIL 505
+++ + LG +M K A RS + LG I SDKTGTLT N +
Sbjct: 313 AVITTCLALGTR-------RMARKN----AIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361
Query: 506 T----------------FNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFHNAAL 549
+ ++ ISG Y P+ E R + P +F L AL
Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGE--VRQGDQPVRCGQFDGLVELATICAL 419
Query: 550 LHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYV 609
+ + +EA + ++ T + + QA S E A A N
Sbjct: 420 CNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERA---GACNTVIK 476
Query: 610 FLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVR----KPEG-AICLYTKGADT 664
L R + T ++F+ RK MSV P G ++ KGA
Sbjct: 477 QLMRKEFT-----------------LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPE 519
Query: 665 VIFERL------HRRGAMEFATEEALAA------FAQETLRTLCLAYREVAEDIYEDWQQ 712
+ ER R + + E + A +TLR L LA R+ A ED +
Sbjct: 520 SVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRD-APPRKEDMEL 578
Query: 713 RHQEASLLLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVN 772
+ S +Q +G + D + V I ++ I++ ++TGD + TAV
Sbjct: 579 --DDCSKFVQYETDL--TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVA 634
Query: 773 I 773
I
Sbjct: 635 I 635
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 55.8 bits (133), Expect = 3e-07
Identities = 67/309 (21%), Positives = 133/309 (43%), Gaps = 25/309 (8%)
Query: 897 RAFVDLASKCQAVIC------CRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTA 950
R F DL+ + Q C RV P K+ IV ++ ++++ + GDG ND +K A
Sbjct: 656 REFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMT-GDGVNDAPALKKA 714
Query: 951 DVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLV-HGRWSYVRICKFLRYFFYKSMASMM 1009
++G+ + G A ++ VL F + V GR Y + +F+RY S +
Sbjct: 715 EIGIAM-GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLI-SSNVGEV 772
Query: 1010 VQVWFACYNGFTGQ--PLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVV 1067
V ++ G P+ W NL+ LP +G D+ + L +
Sbjct: 773 VCIFLTAILGLPEALIPVQLLW----VNLVTDGLPATALGFNPPDLDIMEKLPR------ 822
Query: 1068 GQKDELFNYWVFVQAIAHGVTTSLVNF-FMTLWISRDTAGP-ASFSDHQSFAVVVALSCL 1125
++ L + W+F + +A GV L T W D GP +F ++F + L
Sbjct: 823 SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPL 882
Query: 1126 LSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSVMS 1185
+ + ++ T + + ++L+++ + + +++ L R+ P P+L +++
Sbjct: 883 FAGIDCEVFESRFPTTMAL-SVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSM 941
Query: 1186 SPSILLVVL 1194
+ L++++
Sbjct: 942 ALHFLILLV 950
Score = 34.3 bits (77), Expect = 0.80
Identities = 107/481 (22%), Positives = 176/481 (36%), Gaps = 85/481 (17%)
Query: 330 DIGNLLLRGCRIRNTDTCYGLVIYAGFDT---KIMKNCGKIHLKRTKLDLLMNKLVVVIF 386
D N+L G I + G+ + G T KI + +RT L +++ +
Sbjct: 203 DKKNMLFSGTNI-TSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLS 261
Query: 387 ISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSM- 445
++ ++C+ + + ++ F D HG S + + F + L IP +
Sbjct: 262 HAISVICVAV---WVINIGHFADP------AHGGSWLRGAVYYFKIAVALAVAAIPEGLP 312
Query: 446 FILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQVEYIFSDKTGTLTQNIL 505
+++ + LG +M K A RS + LG I SDKTGTLT N +
Sbjct: 313 AVITTCLALGTR-------RMARKN----AIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361
Query: 506 T----------------FNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFHNAAL 549
+ ++ ISG Y P+ E R + P +F L AL
Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGE--VRQGDQPVRCGQFDGLVELATICAL 419
Query: 550 LHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYV 609
+ + +EA + ++ T + + QA S E A A N
Sbjct: 420 CNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERA---GACNTVIK 476
Query: 610 FLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVR----KPEG-AICLYTKGADT 664
L R + T ++F+ RK MSV P G ++ KGA
Sbjct: 477 QLMRKEFT-----------------LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPE 519
Query: 665 VIFERL------HRRGAMEFATEEALAA------FAQETLRTLCLAYREVAEDIYEDWQQ 712
+ ER R + + E + A +TLR L LA R+ A ED +
Sbjct: 520 SVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRD-APPRKEDMEL 578
Query: 713 RHQEASLLLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVN 772
+ S +Q +G + D + V I ++ I++ ++TGD + TAV
Sbjct: 579 --DDCSKFVQYETDL--TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVA 634
Query: 773 I 773
I
Sbjct: 635 I 635
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 55.8 bits (133), Expect = 3e-07
Identities = 67/309 (21%), Positives = 133/309 (43%), Gaps = 25/309 (8%)
Query: 897 RAFVDLASKCQAVIC------CRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTA 950
R F DL+ + Q C RV P K+ IV ++ ++++ + GDG ND +K A
Sbjct: 656 REFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMT-GDGVNDAPALKKA 714
Query: 951 DVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLV-HGRWSYVRICKFLRYFFYKSMASMM 1009
++G+ + G A ++ VL F + V GR Y + +F+RY S +
Sbjct: 715 EIGIAM-GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLI-SSNVGEV 772
Query: 1010 VQVWFACYNGFTGQ--PLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVV 1067
V ++ G P+ W NL+ LP +G D+ + L +
Sbjct: 773 VCIFLTAILGLPEALIPVQLLW----VNLVTDGLPATALGFNPPDLDIMEKLPR------ 822
Query: 1068 GQKDELFNYWVFVQAIAHGVTTSLVNF-FMTLWISRDTAGP-ASFSDHQSFAVVVALSCL 1125
++ L + W+F + +A GV L T W D GP +F ++F + L
Sbjct: 823 SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPL 882
Query: 1126 LSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSVMS 1185
+ + ++ T + + ++L+++ + + +++ L R+ P P+L +++
Sbjct: 883 FAGIDCEVFESRFPTTMAL-SVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSM 941
Query: 1186 SPSILLVVL 1194
+ L++++
Sbjct: 942 ALHFLILLV 950
Score = 34.3 bits (77), Expect = 0.80
Identities = 107/481 (22%), Positives = 176/481 (36%), Gaps = 85/481 (17%)
Query: 330 DIGNLLLRGCRIRNTDTCYGLVIYAGFDT---KIMKNCGKIHLKRTKLDLLMNKLVVVIF 386
D N+L G I + G+ + G T KI + +RT L +++ +
Sbjct: 203 DKKNMLFSGTNI-TSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLS 261
Query: 387 ISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSM- 445
++ ++C+ + + ++ F D HG S + + F + L IP +
Sbjct: 262 HAISVICVAV---WVINIGHFADP------AHGGSWLRGAVYYFKIAVALAVAAIPEGLP 312
Query: 446 FILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQVEYIFSDKTGTLTQNIL 505
+++ + LG +M K A RS + LG I SDKTGTLT N +
Sbjct: 313 AVITTCLALGTR-------RMARKN----AIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361
Query: 506 T----------------FNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFHNAAL 549
+ ++ ISG Y P+ E R + P +F L AL
Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGE--VRQGDQPVRCGQFDGLVELATICAL 419
Query: 550 LHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYV 609
+ + +EA + ++ T + + QA S E A A N
Sbjct: 420 CNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERA---GACNTVIK 476
Query: 610 FLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVR----KPEG-AICLYTKGADT 664
L R + T ++F+ RK MSV P G ++ KGA
Sbjct: 477 QLMRKEFT-----------------LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPE 519
Query: 665 VIFERL------HRRGAMEFATEEALAA------FAQETLRTLCLAYREVAEDIYEDWQQ 712
+ ER R + + E + A +TLR L LA R+ A ED +
Sbjct: 520 SVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRD-APPRKEDMEL 578
Query: 713 RHQEASLLLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVN 772
+ S +Q +G + D + V I ++ I++ ++TGD + TAV
Sbjct: 579 --DDCSKFVQYETDL--TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVA 634
Query: 773 I 773
I
Sbjct: 635 I 635
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 55.8 bits (133), Expect = 3e-07
Identities = 67/309 (21%), Positives = 133/309 (43%), Gaps = 25/309 (8%)
Query: 897 RAFVDLASKCQAVIC------CRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTA 950
R F DL+ + Q C RV P K+ IV ++ ++++ + GDG ND +K A
Sbjct: 656 REFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMT-GDGVNDAPALKKA 714
Query: 951 DVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLV-HGRWSYVRICKFLRYFFYKSMASMM 1009
++G+ + G A ++ VL F + V GR Y + +F+RY S +
Sbjct: 715 EIGIAM-GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLI-SSNVGEV 772
Query: 1010 VQVWFACYNGFTGQ--PLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVV 1067
V ++ G P+ W NL+ LP +G D+ + L +
Sbjct: 773 VCIFLTAILGLPEALIPVQLLW----VNLVTDGLPATALGFNPPDLDIMEKLPR------ 822
Query: 1068 GQKDELFNYWVFVQAIAHGVTTSLVNF-FMTLWISRDTAGP-ASFSDHQSFAVVVALSCL 1125
++ L + W+F + +A GV L T W D GP +F ++F + L
Sbjct: 823 SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPL 882
Query: 1126 LSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSVMS 1185
+ + ++ T + + ++L+++ + + +++ L R+ P P+L +++
Sbjct: 883 FAGIDCEVFESRFPTTMAL-SVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSM 941
Query: 1186 SPSILLVVL 1194
+ L++++
Sbjct: 942 ALHFLILLV 950
Score = 34.3 bits (77), Expect = 0.80
Identities = 107/481 (22%), Positives = 176/481 (36%), Gaps = 85/481 (17%)
Query: 330 DIGNLLLRGCRIRNTDTCYGLVIYAGFDT---KIMKNCGKIHLKRTKLDLLMNKLVVVIF 386
D N+L G I + G+ + G T KI + +RT L +++ +
Sbjct: 203 DKKNMLFSGTNI-TSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLS 261
Query: 387 ISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSM- 445
++ ++C+ + + ++ F D HG S + + F + L IP +
Sbjct: 262 HAISVICVAV---WVINIGHFADP------AHGGSWLRGAVYYFKIAVALAVAAIPEGLP 312
Query: 446 FILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQVEYIFSDKTGTLTQNIL 505
+++ + LG +M K A RS + LG I SDKTGTLT N +
Sbjct: 313 AVITTCLALGTR-------RMARKN----AIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361
Query: 506 T----------------FNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFHNAAL 549
+ ++ ISG Y P+ E R + P +F L AL
Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGE--VRQGDQPVRCGQFDGLVELATICAL 419
Query: 550 LHLVRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYV 609
+ + +EA + ++ T + + QA S E A A N
Sbjct: 420 CNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERA---GACNTVIK 476
Query: 610 FLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVR----KPEG-AICLYTKGADT 664
L R + T ++F+ RK MSV P G ++ KGA
Sbjct: 477 QLMRKEFT-----------------LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPE 519
Query: 665 VIFERL------HRRGAMEFATEEALAA------FAQETLRTLCLAYREVAEDIYEDWQQ 712
+ ER R + + E + A +TLR L LA R+ A ED +
Sbjct: 520 SVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRD-APPRKEDMEL 578
Query: 713 RHQEASLLLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVN 772
+ S +Q +G + D + V I ++ I++ ++TGD + TAV
Sbjct: 579 --DDCSKFVQYETDL--TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVA 634
Query: 773 I 773
I
Sbjct: 635 I 635
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,647,038
Number of Sequences: 37866
Number of extensions: 2254471
Number of successful extensions: 10534
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 148
Number of HSP's that attempted gapping in prelim test: 9702
Number of HSP's gapped (non-prelim): 813
length of query: 1300
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1186
effective length of database: 13,930,794
effective search space: 16521921684
effective search space used: 16521921684
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.