Search of human proteins with 42718020

Search of human proteins with 42718020

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42718020 retinitis pigmentosa 9 [Homo sapiens]
         (221 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42718020 retinitis pigmentosa 9 [Homo sapiens]                     460   e-130
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                62   5e-10
gi|168229156 NFKB activating protein [Homo sapiens]                    59   3e-09
gi|169234949 CWF19-like 2, cell cycle control [Homo sapiens]           57   1e-08
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  54   1e-07
gi|27883882 P18SRP protein [Homo sapiens]                              53   2e-07
gi|56090620 NFKB activating protein-like [Homo sapiens]                52   4e-07
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]            52   5e-07
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    49   3e-06
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    48   6e-06
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          48   8e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            47   1e-05
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    47   1e-05
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            47   1e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    47   1e-05
gi|21361684 G patch domain containing 1 [Homo sapiens]                 47   1e-05
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]            47   2e-05
gi|151301228 formin binding protein 3 [Homo sapiens]                   47   2e-05
gi|5803145 ralA binding protein 1 [Homo sapiens]                       46   2e-05
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso...    46   2e-05
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]         46   3e-05
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    46   3e-05
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...    45   4e-05
gi|125656165 THO complex 2 [Homo sapiens]                              45   4e-05
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            45   4e-05
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]    45   4e-05
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]    45   4e-05
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]    45   4e-05
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]     45   4e-05
gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens]     45   4e-05

>gi|42718020 retinitis pigmentosa 9 [Homo sapiens]
          Length = 221

 Score =  460 bits (1184), Expect = e-130
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 1   MSSRPGREDVGAAGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLI 60
           MSSRPGREDVGAAGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLI
Sbjct: 1   MSSRPGREDVGAAGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLI 60

Query: 61  KEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKEC 120
           KEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKEC
Sbjct: 61  KEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKEC 120

Query: 121 PFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSE 180
           PFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSE
Sbjct: 121 PFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSE 180

Query: 181 GKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           GKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE
Sbjct: 181 GKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 61.6 bits (148), Expect = 5e-10
 Identities = 56/232 (24%), Positives = 102/232 (43%), Gaps = 38/232 (16%)

Query: 23  EQELQRRREQKRRRHDAQQL---QQLKHLESFYEKPPPGLIKEDETKPEDCIPDVPGNEH 79
           ++EL ++  +++  +D + L   +++K+  +F  + PPG  KE++ K E         E+
Sbjct: 39  QEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGAKKENKEKEET----EGETEY 94

Query: 80  AREFLAHAPTKGLW--------MPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLE 131
             E+   AP +            P G +V+ ++C +C ++GH   D+ECP F        
Sbjct: 95  KFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINAS 154

Query: 132 QFRVAHEDPMY---DIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEG------- 181
                   P     ++I + +     ++   L + L  +   ++  +S   E        
Sbjct: 155 SVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLK 214

Query: 182 ----KEKHK---------KKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
               K+K K         KKKKK+  KK+K +K + K +KHKSS S+  S S
Sbjct: 215 SLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSS 266



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 3/108 (2%)

Query: 117 DKECPFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSS 176
           D E  F      K +Q  +   D +    +   R +K  +  + K     S+S    SSS
Sbjct: 207 DPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSS 266

Query: 177 SSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRK---HKSSKSNEGSDSE 221
           SSS  +      + +  +K++K ++KK+KK K   H +S S E   S+
Sbjct: 267 SSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSK 314



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 8/84 (9%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKR-------- 197
           +   +H+K             S+S E   SSS SE   K KK ++K++ K +        
Sbjct: 247 KSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSD 306

Query: 198 KKEKKKKKKRKHKSSKSNEGSDSE 221
            +EK K KKRK     S+   + E
Sbjct: 307 SEEKDKSKKRKLHEELSSSHHNRE 330



 Score = 36.2 bits (82), Expect = 0.023
 Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 8/73 (10%)

Query: 147 DNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEK----HKKRKKEKK 202
           +++ + K+ +IQ+ K+     +      ++S SE K+K KK+K  E+    H  R+K K+
Sbjct: 279 ESESNNKEKKIQRKKRKKNKCSGH----NNSDSEEKDKSKKRKLHEELSSSHHNREKAKE 334

Query: 203 KKKKRKHKSSKSN 215
           K +  KH+SS+ +
Sbjct: 335 KPRFLKHESSRED 347



 Score = 32.7 bits (73), Expect = 0.25
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 6/50 (12%)

Query: 176 SSSSEGKEKHKKKKKKEKHKKRKKEKK------KKKKRKHKSSKSNEGSD 219
           SSS   +EK K+K +  KH+  +++ K       KK R HK S    GS+
Sbjct: 323 SSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSE 372



 Score = 31.2 bits (69), Expect = 0.73
 Identities = 22/108 (20%), Positives = 44/108 (40%), Gaps = 14/108 (12%)

Query: 113 HRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDED 172
           +R   KE P F+K     E  + +H D   D      +H  + R              E 
Sbjct: 328 NREKAKEKPRFLKHESSREDSKWSHSDS--DKKSRTHKHSPEKR------------GSER 373

Query: 173 RSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
           +  SS S G+E+  ++ +       K+ + +K+ +++   + +  +DS
Sbjct: 374 KEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDS 421


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 31/76 (40%), Positives = 44/76 (57%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           R  KR +K    ++ K+  EDS SD D  + SS E  ++  KK KK++ KK+ + KK KK
Sbjct: 192 RSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKK 251

Query: 206 KRKHKSSKSNEGSDSE 221
           KR  KS K +  S S+
Sbjct: 252 KRSKKSRKESSDSSSK 267



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 24/58 (41%), Positives = 37/58 (63%)

Query: 164 LEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           +ED    +  +S+S+SE ++K K  + KE+ KKR+K+K  K+K K  S  S+  SDSE
Sbjct: 163 VEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSE 220



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 27/86 (31%)

Query: 155 VRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKE----KHKK-------------- 196
           V  ++ K+    +++ E+     SS  KE+ KK++KK+    KHKK              
Sbjct: 163 VEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETD 222

Query: 197 ---------RKKEKKKKKKRKHKSSK 213
                     KK KKK+KK+KH+S K
Sbjct: 223 SSDEDNKRRAKKAKKKEKKKKHRSKK 248



 Score = 31.2 bits (69), Expect = 0.73
 Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 9/62 (14%)

Query: 169 SDEDRSSSSSSEGKEKHKKKKKKEKHKKR---------KKEKKKKKKRKHKSSKSNEGSD 219
           SDE          K        +E+ KK+         K+ KKK  KRKHK    +  SD
Sbjct: 157 SDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSD 216

Query: 220 SE 221
           S+
Sbjct: 217 SD 218


>gi|169234949 CWF19-like 2, cell cycle control [Homo sapiens]
          Length = 894

 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 33/96 (34%), Positives = 57/96 (59%), Gaps = 3/96 (3%)

Query: 128 QKLEQFRVAHEDPMYDIIRDNKRH-EKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKH- 185
           + +E+ +    +   +++R  K + EK+ R ++LK+L  + T      +    +  ++H 
Sbjct: 16  KSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHS 75

Query: 186 -KKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
            KKKKKK+KH K+ K++KKKK +K K  K+NE SDS
Sbjct: 76  VKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDS 111



 Score = 27.7 bits (60), Expect = 8.1
 Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 127 NQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHK 186
           N+++EQF   H        +   +H K  + ++ K+  +      + SS SSS  +++  
Sbjct: 64  NERIEQFSQEHSVKKK---KKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV 120

Query: 187 KKKKKEKHKKRKKEKKKKKK 206
           +    +   K K  K K +K
Sbjct: 121 EAVPSQTPDKEKAWKVKDEK 140


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 2/83 (2%)

Query: 140 PMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSS-SEGKEKHKKKKKKEKHKKRK 198
           P   + ++ K+  K            DS+SD   SS SS SE   + K KK+K+KH+K  
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238

Query: 199 KEKKKKKKRKHKSSKSNEGSDSE 221
           + K KK+K+K K SK +  S+SE
Sbjct: 239 R-KHKKEKKKRKKSKKSASSESE 260



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 24/154 (15%)

Query: 75  PGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQ------ 128
           P    +R+    + T   W    +  + M+    +R+    GDK     IK NQ      
Sbjct: 344 PSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERW--IKGDKSELNEIKENQRSPVRV 401

Query: 129 ---KLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKH 185
              K+   R   E P       N+++EK+ +++  K      ++ ++R    +SE  +K+
Sbjct: 402 KERKITDHRNVSESP-------NRKNEKEKKVKDHK------SNSKERDIRRNSEKDDKY 448

Query: 186 KKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSD 219
           K K KK    K + + K+K K K + SK N   +
Sbjct: 449 KNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEE 482



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 5/82 (6%)

Query: 145 IRDNKRH--EKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKK--RKKE 200
           ++D+K +  E+D+R    K     +   +   S S S+ KEK K K++  KH +   K+ 
Sbjct: 426 VKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRM 485

Query: 201 KKKKKKRKHKSSKSNE-GSDSE 221
           + + K R H++ K  E  SDS+
Sbjct: 486 RSRSKGRDHENVKEKEKQSDSK 507



 Score = 35.4 bits (80), Expect = 0.039
 Identities = 39/210 (18%), Positives = 86/210 (40%), Gaps = 35/210 (16%)

Query: 16  RRPREPPEQELQRRREQKRR--------RHDAQQLQQLKHLESFYEKPPPGLIKEDETKP 67
           RR   PP    + +R Q+ R        + D  +L ++K       +  P  +KE +   
Sbjct: 354 RRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKE-----NQRSPVRVKERKITD 408

Query: 68  EDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGN 127
              + + P  ++ +E               K+VK  +    +R   R  +K+  +  K  
Sbjct: 409 HRNVSESPNRKNEKE---------------KKVKDHKSNSKERDIRRNSEKDDKYKNKVK 453

Query: 128 QKLE-QFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHK 186
           ++ + + R   ++      RD+K +  + +  + +    D  + +++   S S+GK++ +
Sbjct: 454 KRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQER 513

Query: 187 KKKKKEKHKKRKKEKKKKKKRKHKSSKSNE 216
            + K+      K ++ + K  +H  SKS E
Sbjct: 514 SRSKE------KSKQLESKSNEHDHSKSKE 537



 Score = 34.3 bits (77), Expect = 0.086
 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 5/63 (7%)

Query: 156 RIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKK---KKRKHKSS 212
           R +  ++   DS S E     S S  K+K++ ++ K  H+K   E +K+   K R H SS
Sbjct: 617 RSKDRRRRRRDSRSSE--REESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSS 674

Query: 213 KSN 215
            ++
Sbjct: 675 NNS 677



 Score = 31.6 bits (70), Expect = 0.56
 Identities = 17/79 (21%), Positives = 41/79 (51%), Gaps = 5/79 (6%)

Query: 148 NKRHEKDVRIQQLKQLLEDSTSDEDRSSSSS-SEGKEKHKKKKKKEKHKKRK----KEKK 202
           N R  +  R +   + +   T D DRS S      +E+  +++ + + ++R+    + + 
Sbjct: 559 NSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRS 618

Query: 203 KKKKRKHKSSKSNEGSDSE 221
           K ++R+ + S+S+E  +S+
Sbjct: 619 KDRRRRRRDSRSSEREESQ 637



 Score = 31.6 bits (70), Expect = 0.56
 Identities = 16/58 (27%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 167 STSDEDRSSSSSSEGKEKHKKKK---KKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           S S E R+    S  K++ ++++     E+ + + + K K + ++ KSS   E S+SE
Sbjct: 604 SRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESE 661


>gi|27883882 P18SRP protein [Homo sapiens]
          Length = 155

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 32/91 (35%), Positives = 51/91 (56%), Gaps = 7/91 (7%)

Query: 128 QKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKK 187
           Q L++ R+  E+      +  K  EK    ++ K+    S+++ED S     + ++K KK
Sbjct: 63  QALQEKRINEEEEK----KKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKK 118

Query: 188 KKKKEKHKK---RKKEKKKKKKRKHKSSKSN 215
           K+KK K KK    KKEKKK+KK KH S+ ++
Sbjct: 119 KEKKSKSKKGKHHKKEKKKRKKEKHSSTPNS 149



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 38/125 (30%), Positives = 60/125 (48%), Gaps = 17/125 (13%)

Query: 108 CKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRD------NKRHEKDVRIQQLK 161
           C +   R G K+C +   G+   E       DP  DI+ D          E++  + +L+
Sbjct: 6   CNKDSVRAGCKKCGY--PGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQ 63

Query: 162 QLLEDSTSDEDRSSSSSSEGKEKHKKKKKK--------EKHKKRKKEK-KKKKKRKHKSS 212
            L E   ++E+      S+ K K KKK+K+        E   K+KK+K +KK+K+K K S
Sbjct: 64  ALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKS 123

Query: 213 KSNEG 217
           KS +G
Sbjct: 124 KSKKG 128



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 16/55 (29%), Positives = 27/55 (49%)

Query: 152 EKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
           E+D   Q+ ++  +     E +S S   +  +K KKK+KKEKH       +  +K
Sbjct: 101 EEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155


>gi|56090620 NFKB activating protein-like [Homo sapiens]
          Length = 402

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 33/75 (44%), Positives = 42/75 (56%), Gaps = 2/75 (2%)

Query: 149 KRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKE-KHKKKKKKEKHK-KRKKEKKKKKK 206
           KR  K  + +  K    DS S+ D +S S  + K  K KKKKKK+KHK K+KK KK KK+
Sbjct: 188 KRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKE 247

Query: 207 RKHKSSKSNEGSDSE 221
               S K +E   SE
Sbjct: 248 SSDSSCKDSEEDLSE 262



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 26/68 (38%), Positives = 41/68 (60%)

Query: 148 NKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKR 207
           NK+  K+   ++  +   DS S+ +  ++S S+  +K  K KKK+K KK K +KKK KK 
Sbjct: 185 NKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKT 244

Query: 208 KHKSSKSN 215
           K +SS S+
Sbjct: 245 KKESSDSS 252



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 34/97 (35%), Positives = 41/97 (42%), Gaps = 28/97 (28%)

Query: 152 EKDVRIQQLKQLLEDSTSDEDRSSSSS-SEGKEKHKKKKKKEKH---------------- 194
           E +  +   K    DS S+E R   +S S  K+K K K  K KH                
Sbjct: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNS 214

Query: 195 -----KKRKKEKKKKKKRKHKSSK------SNEGSDS 220
                KKR K KKKKKK+KHK+ K        E SDS
Sbjct: 215 DSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDS 251



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 2/59 (3%)

Query: 164 LEDSTSDEDRSSSSSSEGKEKHKKKK--KKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
           +ED      + SSSS    E+H+KKK  +    KKRK +  K+K RK+  S SN  SD+
Sbjct: 154 VEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDT 212


>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 170

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 12/92 (13%)

Query: 137 HEDPMYDIIRDNKRHEKDVRIQQLKQL------------LEDSTSDEDRSSSSSSEGKEK 184
           H DP   ++  +  H    +I  L  +            L      E++      + K+K
Sbjct: 57  HSDPSATVLPGSSTHRLKGKIFHLISIAFCDAGPSLHLPLHGLPQREEKKEKEKEKKKKK 116

Query: 185 HKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNE 216
            KKKKKK+K KK+KK+KKKKKK+K K  +  +
Sbjct: 117 KKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK 148



 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 6/79 (7%)

Query: 140 PMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKK 199
           P++ + +  ++ EK+      K+  +     + +      + K+K KKKKKK K K+++K
Sbjct: 95  PLHGLPQREEKKEKE------KEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK 148

Query: 200 EKKKKKKRKHKSSKSNEGS 218
            K+KKK++K K    NEG+
Sbjct: 149 RKRKKKRKKKKKKTGNEGA 167



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 23/61 (37%), Positives = 37/61 (60%)

Query: 161 KQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
           K+  E     + +      + K+K KKKKKK+K KKRK+++K+K+KRK K  K  + + +
Sbjct: 105 KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGN 164

Query: 221 E 221
           E
Sbjct: 165 E 165



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 22/69 (31%), Positives = 40/69 (57%)

Query: 151 HEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHK 210
           H    R ++ ++  E     + +      + K+K KKKKKK+K +KRK+++K+K+K+K K
Sbjct: 97  HGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156

Query: 211 SSKSNEGSD 219
             K   G++
Sbjct: 157 KKKKKTGNE 165



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 18/77 (23%), Positives = 39/77 (50%), Gaps = 5/77 (6%)

Query: 137 HEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKK 196
           H  P  +  ++ ++ +K  + ++ K+  +     + +      + K K K+K+K+     
Sbjct: 97  HGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKR----- 151

Query: 197 RKKEKKKKKKRKHKSSK 213
           +KK KKKKKK  ++ +K
Sbjct: 152 KKKRKKKKKKTGNEGAK 168


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 1/77 (1%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHK-KRKKEKKKK 204
           +  K+ ++    ++ ++  E+   +  R      + KEK KKKK KE  K K K+E++KK
Sbjct: 2   KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61

Query: 205 KKRKHKSSKSNEGSDSE 221
           +KRK K  K  E  + E
Sbjct: 62  RKRKRKKKKEEEEREEE 78



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 24/76 (31%), Positives = 45/76 (59%), Gaps = 3/76 (3%)

Query: 149 KRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHK---KRKKEKKKKK 205
           K+ +K  +  +  +  E++  +E++      + KEK K+K+KK+K K   KRK++++++K
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 206 KRKHKSSKSNEGSDSE 221
           KRK K  K  E  + E
Sbjct: 61  KRKRKRKKKKEEEERE 76



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 3/71 (4%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDST---SDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKK 202
           R  K  E+  R ++ K+  E+      +E+       E KE+ +++KKK+K +++++E++
Sbjct: 52  RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111

Query: 203 KKKKRKHKSSK 213
           KKKKR+ K+ K
Sbjct: 112 KKKKRRRKTKK 122



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 8/73 (10%)

Query: 149 KRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKH--------KKKKKKEKHKKRKKE 200
           KR EK+   ++ K+  +    +E+R      E +EK         ++KKKK++ +K ++E
Sbjct: 51  KRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110

Query: 201 KKKKKKRKHKSSK 213
           +KKKK+R+    K
Sbjct: 111 EKKKKRRRKTKKK 123



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 19/65 (29%), Positives = 39/65 (60%), Gaps = 3/65 (4%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           R  KR +K    ++ ++  E+   +E++      EG+ + KKKK++ K ++ +K+KK+++
Sbjct: 62  RKRKRKKKK---EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118

Query: 206 KRKHK 210
           K K K
Sbjct: 119 KTKKK 123



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 9/85 (10%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKR-------- 197
           ++ KR EK    ++ K+  + +   E R      E K K K+KKKKE+ ++         
Sbjct: 25  KEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEE 84

Query: 198 -KKEKKKKKKRKHKSSKSNEGSDSE 221
            K+E++K++ R+ K  K     + E
Sbjct: 85  EKEEEEKEEGRRRKKKKKRRRKEEE 109



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 13/70 (18%), Positives = 42/70 (60%)

Query: 152 EKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKS 211
           E++ +  + K+  ++   ++++   +    K K K++++K++ +KRKK+K+++++ + + 
Sbjct: 21  EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80

Query: 212 SKSNEGSDSE 221
            +  E  + E
Sbjct: 81  EEEEEKEEEE 90



 Score = 36.6 bits (83), Expect = 0.017
 Identities = 18/80 (22%), Positives = 44/80 (55%)

Query: 125 KGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEK 184
           K  ++ E+ +   E+      +  K+ E++ R ++ ++  E+   +E        + K++
Sbjct: 44  KKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103

Query: 185 HKKKKKKEKHKKRKKEKKKK 204
            +K++++EK KKR+++ KKK
Sbjct: 104 RRKEEEEEKKKKRRRKTKKK 123



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 21/92 (22%), Positives = 46/92 (50%), Gaps = 10/92 (10%)

Query: 125 KGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEK 184
           K  ++ E+     E+   +  R  KR EK    ++ K+  E     E          KE+
Sbjct: 8   KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKE----------KEE 57

Query: 185 HKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNE 216
            +KK+K+++ KK+++E++++++ + +  K  E
Sbjct: 58  EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEE 89


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 24/48 (50%), Positives = 28/48 (58%)

Query: 174 SSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           SS    EGK   K+KKKK+K  K ++EK  KKK KHK SK  E    E
Sbjct: 640 SSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEE 687



 Score = 30.8 bits (68), Expect = 0.96
 Identities = 11/39 (28%), Positives = 26/39 (66%)

Query: 178 SSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNE 216
           +++ K KHKK K KE+ K+ ++ ++++  R  + + ++E
Sbjct: 668 AAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADE 706


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 52/225 (23%), Positives = 95/225 (42%), Gaps = 31/225 (13%)

Query: 13  AGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPG------LIKED--- 63
           A +R   +P  + L  +  +K  + +  ++ ++ H+E    KPP        ++K+D   
Sbjct: 539 ADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVE----KPPKVESKEKVMVKKDKPI 594

Query: 64  --ETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKEC- 120
             ETKP     +VP  E      A    K       K  K            +T  KE  
Sbjct: 595 KTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAK-----------EKTVKKETK 643

Query: 121 --PFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSS 178
             P   K  ++  +  VA ++    I ++ K  +++V+ +  K++ ++   +  +     
Sbjct: 644 VKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKE 703

Query: 179 SEGKEKHKKKKKKEKH--KKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           +  KE  K+ KK+EK   KK +KE KK+ K+  K +K +    SE
Sbjct: 704 TPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSE 748


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 20/76 (26%), Positives = 44/76 (57%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           R  +R E++ R ++ ++  +     +++      E +E+ K++++KE  +  +KEK+KKK
Sbjct: 59  RKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKK 118

Query: 206 KRKHKSSKSNEGSDSE 221
           ++K +   S EG + E
Sbjct: 119 EKKERGRTSKEGKERE 134



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 20/71 (28%), Positives = 44/71 (61%), Gaps = 3/71 (4%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           R+ +R  K+ + ++ KQ+ E    +E+R      E K++ + +K+++K ++RK+ +++KK
Sbjct: 154 REKERERKERKKRERKQVGE---KEEERKEKERKERKKRERNRKERKKERERKERRERKK 210

Query: 206 KRKHKSSKSNE 216
           +RK K  +  E
Sbjct: 211 ERKKKEERKKE 221



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 24/101 (23%), Positives = 52/101 (51%), Gaps = 4/101 (3%)

Query: 125 KGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDE----DRSSSSSSE 180
           K  +K E+ R + E    +   + KR E+  R ++ ++  ++    E    +R      E
Sbjct: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE 175

Query: 181 GKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
            + K K++K+++K ++ +KE+KK+++RK +  +  E    E
Sbjct: 176 EERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 21/79 (26%), Positives = 44/79 (55%), Gaps = 3/79 (3%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKK---KKKKEKHKKRKKEKK 202
           ++NK  E+  + ++ ++     TS E +      E K + +K   +KK+E+ K+R+++++
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKER 163

Query: 203 KKKKRKHKSSKSNEGSDSE 221
           KK++RK    K  E  + E
Sbjct: 164 KKRERKQVGEKEEERKEKE 182



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 7/80 (8%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHK----KRKKEK 201
           R  +R +K+ + ++ K   E+    + R    + EG+EK K+KKK++K +    K  KE+
Sbjct: 77  RKRERGKKEKKGERKK---EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133

Query: 202 KKKKKRKHKSSKSNEGSDSE 221
           ++K++RK +  K  E    E
Sbjct: 134 ERKEERKREERKERERKKEE 153



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 18/61 (29%), Positives = 36/61 (59%), Gaps = 10/61 (16%)

Query: 171 EDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK----------KRKHKSSKSNEGSDS 220
           ++R S    E +E+ K+K+++EK +KR++ KK+KK          K++ +  ++ EG + 
Sbjct: 53  KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112

Query: 221 E 221
           E
Sbjct: 113 E 113



 Score = 36.6 bits (83), Expect = 0.017
 Identities = 40/210 (19%), Positives = 94/210 (44%), Gaps = 18/210 (8%)

Query: 4   RPGREDVGAAGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKED 63
           + G+++  +   +  RE  +++ +R +E+KR R   ++  + K  E   +K      +E 
Sbjct: 49  KEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR----REK 104

Query: 64  ETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRC---KRYGHRTGDKEC 120
           E K         G E  +        +G     GKE +  +  +    K    +  ++E 
Sbjct: 105 ENKE--------GEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156

Query: 121 PFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSE 180
               K  +K E+ +V  ++   +  ++ +R E+  R +  K+  ++    E R      +
Sbjct: 157 ERERKERKKRERKQVGEKE---EERKEKERKERKKRERNRKERKKERERKERRERKKERK 213

Query: 181 GKEKHKKKKKKEKHKKRKKEKKKKKKRKHK 210
            KE+ KK+++K++    +++++ K++RK +
Sbjct: 214 KKEERKKERQKDRQTNWREKERGKRERKER 243



 Score = 32.7 bits (73), Expect = 0.25
 Identities = 18/72 (25%), Positives = 37/72 (51%), Gaps = 4/72 (5%)

Query: 149 KRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEK----KKK 204
           +  EK+ + ++ K+  +     E+R        KE  + ++K+++ KK KKE+    K+ 
Sbjct: 71  REREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130

Query: 205 KKRKHKSSKSNE 216
           K+R+ K  +  E
Sbjct: 131 KERERKEERKRE 142


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 21/40 (52%), Positives = 28/40 (70%)

Query: 182 KEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           KEK KKK KKEK KK++KEK+KK+K + K  +  E  + E
Sbjct: 697 KEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKE 736



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 19/54 (35%), Positives = 35/54 (64%), Gaps = 1/54 (1%)

Query: 161 KQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKK-RKKEKKKKKKRKHKSSK 213
           K+ +++    +D+      + KEK KK+K++EK K+ R+K +K+K+K KH+  K
Sbjct: 693 KEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIK 746



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 10/67 (14%)

Query: 157 IQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHK----------KRKKEKKKKKK 206
           +  L  +L +   +E        + K+K +KKKKKEK K          KR++EK++K+K
Sbjct: 678 LPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEK 737

Query: 207 RKHKSSK 213
            KHK  K
Sbjct: 738 EKHKHEK 744



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 19/40 (47%), Positives = 26/40 (65%)

Query: 182 KEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           K K K+KKK +K KK+KKEK+K+KK K +  +  E    E
Sbjct: 695 KVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKRE 734



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 17/40 (42%), Positives = 27/40 (67%)

Query: 182 KEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           KEK K KK+K+K K+++KEKK+K++ K K  +     + E
Sbjct: 699 KEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKE 738



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 17/57 (29%), Positives = 34/57 (59%)

Query: 160 LKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNE 216
           L  L E    ++++      +  +K KKKKK+++ +K++KE++K+K+ + K  K  E
Sbjct: 682 LPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKE 738



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 18/39 (46%), Positives = 25/39 (64%)

Query: 183 EKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           E+ +K K+KEK K +K++KKKK+K K K  K  E    E
Sbjct: 691 EEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKRE 729



 Score = 34.3 bits (77), Expect = 0.086
 Identities = 15/29 (51%), Positives = 21/29 (72%)

Query: 182 KEKHKKKKKKEKHKKRKKEKKKKKKRKHK 210
           KEKHK KKK  +  K+ K+K++K+K K K
Sbjct: 613 KEKHKDKKKDREKGKKDKDKREKEKVKDK 641



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 6/58 (10%)

Query: 170 DEDRSSSSSSEGKEKHKKK-----KKKEKHKKRKKEK-KKKKKRKHKSSKSNEGSDSE 221
           +E     SS E K+K KK+     KKKEK + R++EK K K K K K     +  D E
Sbjct: 510 EEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKE 567



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 14/26 (53%), Positives = 20/26 (76%)

Query: 188 KKKKEKHKKRKKEKKKKKKRKHKSSK 213
           +K+KEKHK +KK+++K KK K K  K
Sbjct: 610 RKEKEKHKDKKKDREKGKKDKDKREK 635



 Score = 32.7 bits (73), Expect = 0.25
 Identities = 15/29 (51%), Positives = 20/29 (68%)

Query: 182 KEKHKKKKKKEKHKKRKKEKKKKKKRKHK 210
           KEK K K KK+  +K KK+K K++K K K
Sbjct: 611 KEKEKHKDKKKDREKGKKDKDKREKEKVK 639



 Score = 32.3 bits (72), Expect = 0.33
 Identities = 19/73 (26%), Positives = 37/73 (50%), Gaps = 3/73 (4%)

Query: 139 DPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKK-KKKEKHKKR 197
           +P++ +  +  +    V ++  K+L ++  +   +        +EK K K K KEK K +
Sbjct: 503 EPLHKVYEEKTKLPSSVEVK--KKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVK 560

Query: 198 KKEKKKKKKRKHK 210
           +KEK K+  R+ K
Sbjct: 561 EKEKDKETGRETK 573



 Score = 31.6 bits (70), Expect = 0.56
 Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 3/62 (4%)

Query: 149 KRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRK 208
           K  E+  ++++ ++  +     + +      + KE+ K+K+++E   KR+KEK+K K  K
Sbjct: 688 KLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKRERE---KREKEKEKHKHEK 744

Query: 209 HK 210
            K
Sbjct: 745 IK 746



 Score = 31.2 bits (69), Expect = 0.73
 Identities = 15/40 (37%), Positives = 23/40 (57%)

Query: 180 EGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSD 219
           +G  + +K+K K+K K R+K KK K KR+ +  K     D
Sbjct: 606 DGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGRED 645



 Score = 30.8 bits (68), Expect = 0.96
 Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 1/36 (2%)

Query: 187 KKKKKEKHKKRKKEKKK-KKKRKHKSSKSNEGSDSE 221
           +K  +EK K ++KEKKK KK++K K  K  E  + E
Sbjct: 687 EKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKE 722



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 2/52 (3%)

Query: 149 KRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKE 200
           K  +KD + ++ K+  E    +++R        +EK +K+K+K KH+K K E
Sbjct: 699 KEKKKDKKEKKKKKEKEKEKKEKEREKEKRE--REKREKEKEKHKHEKIKVE 748



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 6/65 (9%)

Query: 158 QQLKQLLEDST---SDEDRSSSSSSEGKEKHKKKKK---KEKHKKRKKEKKKKKKRKHKS 211
           + L ++ E+ T   S  +       E K K KKK+K   +E+ K + K+K K+K +  + 
Sbjct: 503 EPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEK 562

Query: 212 SKSNE 216
            K  E
Sbjct: 563 EKDKE 567


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 23/76 (30%), Positives = 47/76 (61%), Gaps = 1/76 (1%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           R  ++ EK+   ++ K+        E +   +  E K++ ++K+++E+ K+RKKE++KKK
Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203

Query: 206 KRKHKSSKSNEGSDSE 221
           +RK K  K++  +DS+
Sbjct: 204 ERK-KDRKTDRQTDSQ 218



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 19/72 (26%), Positives = 42/72 (58%), Gaps = 1/72 (1%)

Query: 146 RDNKRHEKDVRIQQL-KQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKK 204
           R  +R E++ R ++  K+   +    E +       GKE+ +K+K++EK +K ++EK+++
Sbjct: 36  RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95

Query: 205 KKRKHKSSKSNE 216
           K++K K  +  +
Sbjct: 96  KRKKEKKKRERK 107



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 18/76 (23%), Positives = 41/76 (53%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           ++ ++ +K+ + ++ KQ        +        E K++ ++K+KK + KKR+KE+K++K
Sbjct: 92  KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151

Query: 206 KRKHKSSKSNEGSDSE 221
           +R  +  K  +    E
Sbjct: 152 ERGKRERKRKKRKKEE 167



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 20/52 (38%), Positives = 32/52 (61%), Gaps = 3/52 (5%)

Query: 173 RSSSSSSEGKEKHKKKKKKEKHKKR---KKEKKKKKKRKHKSSKSNEGSDSE 221
           R S    E +E+ K+K+++EK +KR   KKEKKK+KKR+    +  +  + E
Sbjct: 32  RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE 83



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 22/81 (27%), Positives = 46/81 (56%), Gaps = 6/81 (7%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKR-----KKE 200
           ++ K+ E+  R ++ ++  ++   + +R +    E K K ++KKK+ K +KR     K+E
Sbjct: 99  KEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRRKERKREKERGKRE 157

Query: 201 KKKKKKRKHKSSKSNEGSDSE 221
           +K+KK++K +  K  E +  E
Sbjct: 158 RKRKKRKKEEREKKRERNRKE 178



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKR---KKEKK 202
           ++ +R  K  R ++ K+  +     E +      + + K KK+KK+E+ KKR   +KE+K
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180

Query: 203 KKKKRKHKSSKSNE 216
           K+++RK +  +  E
Sbjct: 181 KERERKERRERKKE 194



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 17/76 (22%), Positives = 42/76 (55%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           R  +R +K+ + ++ ++  ++             E +EK ++K+KKEK K+ +K++ +++
Sbjct: 54  RKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRE 113

Query: 206 KRKHKSSKSNEGSDSE 221
           ++K K  K  E  + +
Sbjct: 114 RKKKKERKERERENKQ 129



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 6/82 (7%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEG---KEKHKKKKKKEKHKKRKKEKK 202
           R  K+  K  R ++ K+  E    +  R      E    +E+++K++KKE+ +K ++E+K
Sbjct: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192

Query: 203 K---KKKRKHKSSKSNEGSDSE 221
           K   K++RK K  K +  +D +
Sbjct: 193 KERKKERRKKKERKKDRKTDRQ 214



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 19/83 (22%), Positives = 43/83 (51%), Gaps = 7/83 (8%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKK-------RK 198
           R+ KR E++ + ++ ++        E +       G+ + KKKK++++ ++       RK
Sbjct: 75  RERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134

Query: 199 KEKKKKKKRKHKSSKSNEGSDSE 221
           ++K++KKKR+ +  +  E    E
Sbjct: 135 RKKRRKKKRRKERKREKERGKRE 157



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 1/73 (1%)

Query: 149 KRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRK 208
           K+ E+  R ++ KQ  E       R      E K + ++ K++ K KKRKKE+++KK+ +
Sbjct: 116 KKKERKERERENKQRRERKRKKR-RKKKRRKERKREKERGKRERKRKKRKKEEREKKRER 174

Query: 209 HKSSKSNEGSDSE 221
           ++  +  E    E
Sbjct: 175 NRKERKKERERKE 187



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 4/61 (6%)

Query: 165 EDSTSDEDRSSSSSSEGKEKHKK----KKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
           E     E R        +EK +K    KK+K+K KKR++ K++++KRK +  +  E  + 
Sbjct: 33  ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92

Query: 221 E 221
           E
Sbjct: 93  E 93



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 21/68 (30%), Positives = 39/68 (57%), Gaps = 3/68 (4%)

Query: 155 VRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKK-KKKKEKHKKRKKEKKKKKKRKHKSSK 213
           V++    Q++  S   +  +   S   KE+ ++ K+K+E+ K+RK+E+ KK+K+K K  K
Sbjct: 11  VKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRK--K 68

Query: 214 SNEGSDSE 221
              G + E
Sbjct: 69  RERGKERE 76



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 5/64 (7%)

Query: 158 QQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKK-----KEKHKKRKKEKKKKKKRKHKSS 212
           ++ K+  E      +R      E  +K KKK+K     KE+ +KRK+ +K++K+R+ K  
Sbjct: 35  ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94

Query: 213 KSNE 216
           +  +
Sbjct: 95  RKRK 98



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 14/68 (20%), Positives = 42/68 (61%)

Query: 149 KRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRK 208
           KR +++   ++ ++  E     ++R      + K++ KK+++K++ ++ +K+KK++K+R+
Sbjct: 65  KRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERE 124

Query: 209 HKSSKSNE 216
            ++ +  E
Sbjct: 125 RENKQRRE 132


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 55/228 (24%), Positives = 94/228 (41%), Gaps = 23/228 (10%)

Query: 6   GREDVGAAGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKEDET 65
           G+++     A  PREPP Q  +R+R  K+      +L + +HLE    +PP       +T
Sbjct: 428 GQQEAKTDQADGPREPP-QSARRKRSYKQA---VSELDEEQHLEDEELQPP-----RSKT 478

Query: 66  KPEDCIPDVPGNEHAREFLAHAPTKGLWM-PLGKEVKVMQCWRCKRYGHRTGDKECPFFI 124
               C P        R FL       + M P      VM+ +  KR      D +C F  
Sbjct: 479 PSSPC-PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSF-IKRNTPLRMDPKCSFVE 536

Query: 125 KGNQKLEQFRVAHEDPMY---DIIRDNKRHEKDVRI---QQLKQLLEDSTSDEDRSSSSS 178
           K  Q+LE  R   E        +  D +R  ++V++   ++L+++L+     E       
Sbjct: 537 KERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKK 596

Query: 179 SEGKEK-----HKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
            + ++K      K +K KE+    +K KKK   +K +  ++    + E
Sbjct: 597 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 644



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 19/76 (25%), Positives = 41/76 (53%), Gaps = 1/76 (1%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           R+ +R E++ R Q+ +QL E     E     +  E +E+ K  + +++  +R+ E+KKKK
Sbjct: 703 REQERREQERREQE-RQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 761

Query: 206 KRKHKSSKSNEGSDSE 221
           + + + ++     + E
Sbjct: 762 EEQQRLAERQLQEEQE 777



 Score = 28.1 bits (61), Expect = 6.2
 Identities = 16/70 (22%), Positives = 39/70 (55%), Gaps = 1/70 (1%)

Query: 145 IRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKK 204
           + + +R  +  R+Q  ++L E   +   +      E +EK KKK+++++  +R+ +++++
Sbjct: 719 LAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK-KKKEEQQRLAERQLQEEQE 777

Query: 205 KKRKHKSSKS 214
           KK K  +  S
Sbjct: 778 KKAKEAAGAS 787


>gi|21361684 G patch domain containing 1 [Homo sapiens]
          Length = 931

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 20/60 (33%), Positives = 38/60 (63%)

Query: 161 KQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
           +Q LE    ++ + +    + K++H++KK+K+K  ++ K K K+K +K + S S+E SDS
Sbjct: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS 902



 Score = 35.4 bits (80), Expect = 0.039
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 4/52 (7%)

Query: 170 DEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           D+ ++       KEK KK  +K KHK ++K KK +K     SS+S++ SDS+
Sbjct: 859 DKHKAKKEHRRKKEKKKK-HRKHKHKGKQKNKKPEKS---SSSESSDSSDSQ 906


>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 23/69 (33%), Positives = 45/69 (65%), Gaps = 1/69 (1%)

Query: 149 KRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKK-KEKHKKRKKEKKKKKKR 207
           K+ +K    ++     +  T+   ++++++++ KEK K+K+K KEK K+++KEK+KKKK+
Sbjct: 43  KKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKK 102

Query: 208 KHKSSKSNE 216
           K K  K  +
Sbjct: 103 KKKKKKKKK 111



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 19/47 (40%), Positives = 35/47 (74%)

Query: 167 STSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSK 213
           +T+ +++      E +++ +K+K+KEK KK+KK+KKKKKK+K  ++K
Sbjct: 70  TTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAK 116



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 19/52 (36%), Positives = 34/52 (65%)

Query: 156 RIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKR 207
           R    K+    +T ++++      E +++ +K+K+KEK KK+KK+KKKKKK+
Sbjct: 61  RTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKK 112



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 18/42 (42%), Positives = 23/42 (54%)

Query: 165 EDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
           E     E        + KEK K+KKKK+K KK+KK+KK   K
Sbjct: 75  EKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAK 116



 Score = 34.3 bits (77), Expect = 0.086
 Identities = 22/81 (27%), Positives = 43/81 (53%), Gaps = 14/81 (17%)

Query: 149 KRHEKDVRIQQLKQLL--EDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKE------ 200
           K+ +K   +++ K+    + +T+   + ++++ +      K+K+KEK K+++KE      
Sbjct: 34  KKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKE 93

Query: 201 ------KKKKKKRKHKSSKSN 215
                 KKKKKK+K K  K N
Sbjct: 94  KEKEKKKKKKKKKKKKKKKLN 114



 Score = 33.1 bits (74), Expect = 0.19
 Identities = 14/43 (32%), Positives = 26/43 (60%)

Query: 161 KQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKK 203
           K+  ++   ++++      E +++ KKKKKK+K KK+KK   K
Sbjct: 74  KEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAK 116



 Score = 32.7 bits (73), Expect = 0.25
 Identities = 16/68 (23%), Positives = 40/68 (58%), Gaps = 1/68 (1%)

Query: 149 KRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRK 208
           K+ +K    ++ K   +  T+ + +  +++++ K      K+KEK K+++KEK+K+K+++
Sbjct: 35  KKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTK-KTTTTTTKEKEKEKEKEKEKEKEKEKE 93

Query: 209 HKSSKSNE 216
            +  K  +
Sbjct: 94  KEKEKKKK 101



 Score = 31.6 bits (70), Expect = 0.56
 Identities = 17/43 (39%), Positives = 23/43 (53%)

Query: 171 EDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSK 213
           E  S+      K+  KKKKKK+   K+KK+   KKK   K+ K
Sbjct: 18  EKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKK 60



 Score = 31.2 bits (69), Expect = 0.73
 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 152 EKDVRIQQLKQLLE-DSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHK 210
           +K V ++++  + E +S     R   ++ + K+K    KKK+K   +KK   K KKR   
Sbjct: 5   DKGVAMEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTT 64

Query: 211 SSKSNEGSDSE 221
           + K+   +  E
Sbjct: 65  TKKTTTTTTKE 75



 Score = 30.8 bits (68), Expect = 0.96
 Identities = 18/53 (33%), Positives = 25/53 (47%)

Query: 162 QLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKS 214
           Q L+   + E     +  E   K  +KKK  K KK+KK   KKKK+     K+
Sbjct: 2   QELDKGVAMEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKT 54


>gi|151301228 formin binding protein 3 [Homo sapiens]
          Length = 930

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 9/83 (10%)

Query: 148 NKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKE---------KHKKRK 198
           NK+H K  +    K+    S SD D   S S + +++ + +   E          +KK K
Sbjct: 784 NKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSK 843

Query: 199 KEKKKKKKRKHKSSKSNEGSDSE 221
           K KKK KKR+HKS      ++ E
Sbjct: 844 KHKKKSKKRRHKSDSPESDAERE 866



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 24/99 (24%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGK----EKHKKKKKKEKHK------ 195
           R     + D    + K+   +S S  + SSS+ SE      +KHKKK KK +HK      
Sbjct: 802 RSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPES 861

Query: 196 --KRKKEKKKKKKR------------KHKSSKSNEGSDS 220
             +R+K+KK+K +             KHKS K   G DS
Sbjct: 862 DAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDS 900



 Score = 34.7 bits (78), Expect = 0.066
 Identities = 15/28 (53%), Positives = 17/28 (60%)

Query: 194 HKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           H K KK  KK KK   K S+S  GSDS+
Sbjct: 781 HSKNKKHSKKSKKHHRKRSRSRSGSDSD 808



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 17/76 (22%), Positives = 39/76 (51%), Gaps = 6/76 (7%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           + +K+H+K  + ++ K    +S ++ ++        KEK ++ +K    ++ + + K  K
Sbjct: 840 KKSKKHKKKSKKRRHKSDSPESDAEREKDK------KEKDRESEKDRTRQRSESKHKSPK 893

Query: 206 KRKHKSSKSNEGSDSE 221
           K+  K S + + S SE
Sbjct: 894 KKTGKDSGNWDTSGSE 909


>gi|5803145 ralA binding protein 1 [Homo sapiens]
          Length = 655

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 25/108 (23%)

Query: 135 VAHEDPMYDIIRDNKRH---------EKDVRIQQLKQLLEDSTSDEDRSSS--------- 176
           + HE P  D++ D+++          +K+ R +      EDS+ DE  S S         
Sbjct: 53  ILHEPP--DVVSDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKMKRSKGIH 110

Query: 177 -----SSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSD 219
                S S+ KEK  K K+K K +K K+EK K++K K K SK    +D
Sbjct: 111 VFKKPSFSKKKEKDFKIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAAD 158



 Score = 36.2 bits (82), Expect = 0.023
 Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 25/154 (16%)

Query: 57  PGLIKEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTG 116
           PGL +  E  P   I   P +  + +   H   KG +    K  +    ++    G    
Sbjct: 39  PGLYRTGEPSPPHDILHEPPDVVSDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGD--- 95

Query: 117 DKECPFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSS 176
           + E P  +K ++ +  F+     P +     +K+ EKD +I++           ++    
Sbjct: 96  EAESPSKMKRSKGIHVFK----KPSF-----SKKKEKDFKIKE---------KPKEEKHK 137

Query: 177 SSSEGKEKHKKKKKKEKHK----KRKKEKKKKKK 206
                +EKHK+KK K+       K+ KEKKKKKK
Sbjct: 138 EEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKK 171


>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
           isoform 2 [Homo sapiens]
          Length = 470

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 54/209 (25%), Positives = 89/209 (42%), Gaps = 18/209 (8%)

Query: 16  RRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKEDETKPEDCIPDVP 75
           +R RE   +E +RRRE +R+R   ++ ++ K  E    K    L K D     D + D P
Sbjct: 208 QRMREEKREE-RRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEP 266

Query: 76  GNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRV 135
             +     L   P KG    L K  K  +  +      R   + C    + + +L+  + 
Sbjct: 267 KIK-----LLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKP 321

Query: 136 AHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHK 195
               P  +  RD +  E++    Q + L E      +R      E + + K++ +KEK  
Sbjct: 322 KR--PEDESGRDYREREREYERDQERILRE-----RERLKRQEEE-RRRQKERYEKEKTF 373

Query: 196 KRKKEKKKKKK----RKHKSSKSNEGSDS 220
           KRK+E+ KK+K     K K ++S E   S
Sbjct: 374 KRKEEEMKKEKDTLRDKGKKAESTESIGS 402



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 46/214 (21%), Positives = 89/214 (41%), Gaps = 25/214 (11%)

Query: 7   REDVGAAGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKEDETK 66
           RE+       R R+  E+  + + E+KR+R D ++L+++  +            + D+ K
Sbjct: 215 REERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIP-----------ERDKLK 263

Query: 67  PEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKG 126
            E  I            L   P KG    L K  K  +  +      R   + C    + 
Sbjct: 264 DEPKIK-----------LLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRS 312

Query: 127 NQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLE-DSTSDEDRSSSSSSEGKEKH 185
           + +L+  +   + P  +  RD +  E++    Q + L E +    ++       E  EK 
Sbjct: 313 DSELKDEK--PKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKE 370

Query: 186 KKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSD 219
           K  K+KE+  K++K+  + K +K +S++S   S+
Sbjct: 371 KTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSE 404



 Score = 32.3 bits (72), Expect = 0.33
 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 147 DNKRHEKDV-RIQQLKQLLE-DSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKK 204
           + KR  KD+ +++++ ++ E D   DE +        K   K+  K+EK KK  KE    
Sbjct: 239 EEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSD 298

Query: 205 KKRKHKSSKSNEGSDSE 221
           ++   +S    + SDSE
Sbjct: 299 ERASGQSCTLPKRSDSE 315



 Score = 28.5 bits (62), Expect = 4.7
 Identities = 15/53 (28%), Positives = 30/53 (56%), Gaps = 7/53 (13%)

Query: 161 KQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSK 213
           KQ + +   +E R        +E  +K++++E+ +K K+E+K+K+K   K  K
Sbjct: 207 KQRMREEKREERRR-------REIERKRQREEERRKWKEEEKRKRKDIEKLKK 252



 Score = 27.7 bits (60), Expect = 8.1
 Identities = 12/49 (24%), Positives = 27/49 (55%)

Query: 157 IQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           ++  +++ E+   +  R        +E+ ++K K+E+ +KRK  +K KK
Sbjct: 204 LKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKK 252


>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
          Length = 597

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 26/53 (49%), Positives = 34/53 (64%), Gaps = 9/53 (16%)

Query: 166 DSTSDEDRSSSSSSEGKEKHKKKKK---KEKH------KKRKKEKKKKKKRKH 209
           DS+  +DRS       KEK KKKKK   KEKH      +KRK+EKK+K++R+H
Sbjct: 48  DSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREH 100



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 7/67 (10%)

Query: 162 QLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKK-------EKKKKKKRKHKSSKS 214
           ++ E S S  D S        E+ + K+KK+K KK+ +       E+++K+K + K  + 
Sbjct: 38  EVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKRE 97

Query: 215 NEGSDSE 221
            E  D+E
Sbjct: 98  REHCDTE 104



 Score = 29.6 bits (65), Expect = 2.1
 Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 20/112 (17%)

Query: 96  LGKEVKVMQC-WRC--KRYGHRTGDKECPFFIK--GNQKLEQFRVAHEDPMYDIIRDNKR 150
           +GK+ K  +  WR   + Y  +  +K     +K  G++  E     H+   YD   D++R
Sbjct: 1   MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER 60

Query: 151 --HEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKE 200
             H++  + ++ K   E    DE+R             +K+K+EK +KR++E
Sbjct: 61  ERHKEKKKKKKKKSEKEKHLDDEER-------------RKRKEEKKRKRERE 99



 Score = 29.6 bits (65), Expect = 2.1
 Identities = 17/57 (29%), Positives = 25/57 (43%)

Query: 160 LKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNE 216
           LK +L+   S+    S S  +      +   + +  K KK+KKKKK  K K     E
Sbjct: 28  LKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEE 84


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 22/47 (46%), Positives = 34/47 (72%), Gaps = 1/47 (2%)

Query: 166 DSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSS 212
           DS+S+   SS SSSE + +H++ +++ KHK+R K K+ KK+RK  SS
Sbjct: 199 DSSSNSSSSSESSSESELEHERSRRR-KHKRRPKVKRSKKRRKEASS 244



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 25/61 (40%), Positives = 36/61 (59%), Gaps = 5/61 (8%)

Query: 161  KQLLEDSTSDEDRSSSSSSEGK-EKHK---KKKKKEKHKKRKKEKKK-KKKRKHKSSKSN 215
            KQ    S S+   S+S ++ GK +KHK   K+  K +H K+ KEK K KK +KHK+ K  
Sbjct: 952  KQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRK 1011

Query: 216  E 216
            +
Sbjct: 1012 Q 1012



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 17/40 (42%), Positives = 27/40 (67%)

Query: 174 SSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSK 213
           S  S++     HKK++K++K K +KK KK+K  R+HK +K
Sbjct: 416 SDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTK 455



 Score = 35.4 bits (80), Expect = 0.039
 Identities = 15/26 (57%), Positives = 20/26 (76%)

Query: 180 EGKEKHKKKKKKEKHKKRKKEKKKKK 205
           E K KHKKK KK+KH +R K+ KK++
Sbjct: 433 EKKVKHKKKGKKQKHCRRHKQTKKRR 458



 Score = 29.6 bits (65), Expect = 2.1
 Identities = 16/61 (26%), Positives = 32/61 (52%), Gaps = 3/61 (4%)

Query: 156 RIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKK---EKKKKKKRKHKSS 212
           +  + +  L+ S+  E  S  ++   +EK K+ + +  H K++K   E+K K +R+   S
Sbjct: 797 KYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHS 856

Query: 213 K 213
           K
Sbjct: 857 K 857



 Score = 28.5 bits (62), Expect = 4.7
 Identities = 17/74 (22%), Positives = 31/74 (41%), Gaps = 3/74 (4%)

Query: 141  MYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKE 200
            ++D +R   R  +  R Q+     +  + D+D  S S S  +    K + K +H+ R   
Sbjct: 1277 LFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSR---SKSETKSRHRTRSVS 1333

Query: 201  KKKKKKRKHKSSKS 214
                + R   S+ S
Sbjct: 1334 YSHSRSRSRSSTSS 1347



 Score = 28.1 bits (61), Expect = 6.2
 Identities = 15/65 (23%), Positives = 26/65 (40%)

Query: 150  RHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKH 209
            R+++    +Q     +DS S     S S SE K +H+ +     H + +        R  
Sbjct: 1292 RNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSR 1351

Query: 210  KSSKS 214
              S+S
Sbjct: 1352 SYSRS 1356



 Score = 27.7 bits (60), Expect = 8.1
 Identities = 16/39 (41%), Positives = 20/39 (51%)

Query: 182 KEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
           KEK  K KKK K +K  +  K+ KKR+       E S S
Sbjct: 432 KEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKS 470


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 1153

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 148 NKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGK-EKHKKKKKKEKHKKRKKEKKKKKK 206
           +K  EKDV + + K         + +      E K EK KKK  K K KK +KEK+++ K
Sbjct: 827 SKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTK 886

Query: 207 RKHKSSKSNEGSD 219
            K KS K   GS+
Sbjct: 887 GKKKSKKQPPGSE 899



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 16/40 (40%), Positives = 28/40 (70%)

Query: 180 EGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSD 219
           E + +H++K +K+K +K++KEK+KK KR+H S  +    D
Sbjct: 728 EEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDED 767



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 19/65 (29%), Positives = 33/65 (50%)

Query: 157 IQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNE 216
           IQ+ +      + ++D         K K K+KK KEK + ++K+K+K+KK+  K  K   
Sbjct: 818 IQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKH 877

Query: 217 GSDSE 221
             + E
Sbjct: 878 RKEKE 882



 Score = 35.4 bits (80), Expect = 0.039
 Identities = 16/40 (40%), Positives = 26/40 (65%)

Query: 182 KEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
           +E+ + ++K EK K+RKK K+K+KK K + S     SD +
Sbjct: 728 EEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDED 767



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 49/227 (21%), Positives = 81/227 (35%), Gaps = 41/227 (18%)

Query: 17  RPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKEDETKPEDCIPDVPG 76
           RP E  E+EL RRRE ++         Q +    FY K  P         P+    D PG
Sbjct: 656 RPSEADEEELARRREARK---------QEQANNPFYIKSSPS--------PQKRYQDTPG 698

Query: 77  NEHAR--EFLAHAPTKGLWMPLGKEVKVMQCWRCKRYG--------------------HR 114
            EH    +     P K   +P+  +   ++  R  R                      H 
Sbjct: 699 VEHIPVVQIDLSVPLKVPGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHS 758

Query: 115 TGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRS 174
           +   E    I   Q+++   V  E P   +  D    + +   + L   L+   +D ++ 
Sbjct: 759 SLPTESDEDIAPAQQVDI--VTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKL 816

Query: 175 SSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
                   E  K  +K     ++K +K KKK++KHK  + ++    E
Sbjct: 817 PIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKE 863



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 36/192 (18%), Positives = 83/192 (43%), Gaps = 32/192 (16%)

Query: 16  RRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKEDETKPEDCIPDVP 75
           RR R+  E++ +R++ +++ +   ++   L         P   +    E  PE+ +P   
Sbjct: 731 RRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDE 790

Query: 76  GNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGH----RTGDKECPFFIKGNQKLE 131
            ++   +     P + L + L K +   +    +++ +    ++ +K+ P   K ++K +
Sbjct: 791 DDKDPND-----PYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPK 845

Query: 132 QFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKK 191
                         +  K+H++  R ++ K+        E     S    K+KH+K +K+
Sbjct: 846 --------------KKEKKHKEKERDKEKKK--------EKEKKKSPKPKKKKHRK-EKE 882

Query: 192 EKHKKRKKEKKK 203
           E+ K +KK KK+
Sbjct: 883 ERTKGKKKSKKQ 894


>gi|125656165 THO complex 2 [Homo sapiens]
          Length = 1593

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 56/225 (24%), Positives = 84/225 (37%), Gaps = 34/225 (15%)

Query: 6    GREDVGAAGARRPREPPEQELQRRREQKRRRHDAQ-----------QLQQLKHLES--FY 52
            G E    +G+ +   P     +  REQKRR+ D              L +LK   +  + 
Sbjct: 1381 GGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSSTVKDSLIELKESSAKLYI 1440

Query: 53   EKPPPGLIKEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYG 112
               PP L K  E + +    D    E +RE               +E K  +  + ++  
Sbjct: 1441 NHTPPPLSKSKEREMDKKDLD-KSRERSRE---------------REKKDEKDRKERKRD 1484

Query: 113  HRTGDKECPFFIKGNQKLEQFRVA-----HEDPMYDIIRDNKRHEKDVRIQQLKQLLEDS 167
            H   D+E P  +   +K E   +       E P      + K  EK+      K+   DS
Sbjct: 1485 HSNNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDS 1544

Query: 168  TSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSS 212
               E     SS   KE    K+K EK +KR     K++K+ HKSS
Sbjct: 1545 FKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKHHKSS 1589



 Score = 36.6 bits (83), Expect = 0.017
 Identities = 46/205 (22%), Positives = 87/205 (42%), Gaps = 23/205 (11%)

Query: 24   QELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKEDETKPEDCIPDVPGNEHAREF 83
            QE +R +E  R R  A++++  ++++   + P  G +K     P   IP+ P  E  R  
Sbjct: 1355 QEREREKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPV--PRSDIPE-PEREQKRRK 1411

Query: 84   LAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYD 143
            +   P+      +   +  ++    K Y + T     P   K  ++     +  +D    
Sbjct: 1412 IDTHPSPSHSSTVKDSLIELKESSAKLYINHTP----PPLSKSKER----EMDKKDLDKS 1463

Query: 144  IIRDNKRHEKDVRIQQLKQLLEDSTSDED--------RSSSSSSEGKEKHKKKKKKEKHK 195
              R  +R +KD + ++ ++  + S +D +        R   + + G  KHK +   E   
Sbjct: 1464 RERSREREKKDEKDRKERKR-DHSNNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPY 1522

Query: 196  KRKKEKKKKKKRKHKSSKSNEGSDS 220
              +K+K+K K    KSS   +GSDS
Sbjct: 1523 PNEKDKEKNKS---KSSGKEKGSDS 1544



 Score = 33.1 bits (74), Expect = 0.19
 Identities = 15/47 (31%), Positives = 30/47 (63%)

Query: 160  LKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
            +K + + S++    +SS+ + G   +K  K+ +K K ++KEK+KK+K
Sbjct: 1238 VKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKEKEKEKKEK 1284



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 15/61 (24%), Positives = 32/61 (52%)

Query: 161  KQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
            K+  ++   ++D  +  + E   K  K+K+K K +++ K++K K    +  SKS +  + 
Sbjct: 1300 KEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQERER 1359

Query: 221  E 221
            E
Sbjct: 1360 E 1360



 Score = 28.1 bits (61), Expect = 6.2
 Identities = 20/83 (24%), Positives = 34/83 (40%), Gaps = 6/83 (7%)

Query: 144  IIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKK---- 199
            +I +N+ H KD   +     +++       SSS  S  K      ++ +K ++R +    
Sbjct: 1180 MIPENEFHHKDPPPRNAVASVQNGPGGGPSSSSIGSASKSDESSTEETDKSRERSQCGVK 1239

Query: 200  --EKKKKKKRKHKSSKSNEGSDS 220
               K      K  SS  N GS+S
Sbjct: 1240 AVNKASSTTPKGNSSNGNSGSNS 1262



 Score = 28.1 bits (61), Expect = 6.2
 Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 9/60 (15%)

Query: 166  DSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKE---------KKKKKKRKHKSSKSNE 216
            +S S+ +++   + + K K K+K+KKEK      E         +K K++R +K  K+ E
Sbjct: 1257 NSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARE 1316


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 25/72 (34%), Positives = 45/72 (62%), Gaps = 2/72 (2%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           RD +R  +  R ++ +Q   +   + DR     +E +E+ KK++KKE+ K+RK++KK++K
Sbjct: 130 RDRERERQRQRERE-RQRQRERKRETDRERQRWAE-REERKKERKKERKKERKEKKKEEK 187

Query: 206 KRKHKSSKSNEG 217
           +R+ K  K  EG
Sbjct: 188 RREDKKRKWGEG 199



 Score = 32.3 bits (72), Expect = 0.33
 Identities = 21/85 (24%), Positives = 43/85 (50%), Gaps = 10/85 (11%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKR-------K 198
           R+ +R+ K  R ++ KQ   +   + +R      E + + ++K++ ++ ++R       K
Sbjct: 110 RNRERNRKGGR-ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERK 168

Query: 199 KEKKK--KKKRKHKSSKSNEGSDSE 221
           KE+KK  KK+RK K  +     D +
Sbjct: 169 KERKKERKKERKEKKKEEKRREDKK 193



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 9/71 (12%), Positives = 39/71 (54%)

Query: 146 RDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           RD +R  ++   ++ +    D   + DR +    E + + ++ +++++ ++ ++E ++++
Sbjct: 21  RDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQR 80

Query: 206 KRKHKSSKSNE 216
           +R+ +  +  +
Sbjct: 81  ERQRQRERKRQ 91



 Score = 28.1 bits (61), Expect = 6.2
 Identities = 15/78 (19%), Positives = 42/78 (53%), Gaps = 9/78 (11%)

Query: 146 RDNKRH-EKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRK------ 198
           R   RH E+D +  + K+   +   + DR      E + + ++++++++ ++RK      
Sbjct: 38  RQRDRHRERDRQTDREKE--RERQKERDRQRQRERETERETERQRERQRQRERKRQTDRE 95

Query: 199 KEKKKKKKRKHKSSKSNE 216
           ++K + ++RK ++ ++ E
Sbjct: 96  RDKDRDRERKRETDRNRE 113


>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
          Length = 871

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 6/76 (7%)

Query: 147 DNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
           + K ++KD + +  KQ   DS++D D++  S  +G     K++KKE  +K  K+  KK+ 
Sbjct: 299 ERKTNDKDEKKEDGKQAENDSSND-DKTKKSEGDG----DKEEKKEDSEKEAKKSSKKRN 353

Query: 207 RKHKSSKS-NEGSDSE 221
           RKH    S +EGS SE
Sbjct: 354 RKHSGDDSFDEGSVSE 369



 Score = 29.6 bits (65), Expect = 2.1
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 6/58 (10%)

Query: 148 NKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           N++H  D          E S S+ +  S S    +EK + +  KEK K +++E +K K
Sbjct: 353 NRKHSGDDSFD------EGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPK 404



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 15/60 (25%), Positives = 33/60 (55%)

Query: 147 DNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
           D+++  K    ++ ++   D + DE   S S SE +    +++K+E    ++KEK K+++
Sbjct: 340 DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEE 399



 Score = 28.1 bits (61), Expect = 6.2
 Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 152 EKDVRIQQLKQLLEDSTSDE-DRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHK 210
           EK+ +    K+  + S  D  D  S S SE + +  + +++++  +  KEK+K K+ + +
Sbjct: 342 EKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWE 401

Query: 211 SSKSNEG 217
             K   G
Sbjct: 402 KPKDAAG 408


>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
          Length = 872

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 6/76 (7%)

Query: 147 DNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
           + K ++KD + +  KQ   DS++D D++  S  +G     K++KKE  +K  K+  KK+ 
Sbjct: 299 ERKTNDKDEKKEDGKQAENDSSND-DKTKKSEGDG----DKEEKKEDSEKEAKKSSKKRN 353

Query: 207 RKHKSSKS-NEGSDSE 221
           RKH    S +EGS SE
Sbjct: 354 RKHSGDDSFDEGSVSE 369



 Score = 30.0 bits (66), Expect = 1.6
 Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 147 DNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
           D+++  K    ++ ++   D + DE   S S SE  E  + +++KE+ ++  KEK+K K+
Sbjct: 340 DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES-ESGQAEEEKEEAEEALKEKEKPKE 398

Query: 207 RKHKSSKSNEG 217
            + +  K   G
Sbjct: 399 EEWEKPKDAAG 409


>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
          Length = 875

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 6/76 (7%)

Query: 147 DNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
           + K ++KD + +  KQ   DS++D D++  S  +G     K++KKE  +K  K+  KK+ 
Sbjct: 299 ERKTNDKDEKKEDGKQAENDSSND-DKTKKSEGDG----DKEEKKEDSEKEAKKSSKKRN 353

Query: 207 RKHKSSKS-NEGSDSE 221
           RKH    S +EGS SE
Sbjct: 354 RKHSGDDSFDEGSVSE 369



 Score = 29.6 bits (65), Expect = 2.1
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 6/58 (10%)

Query: 148 NKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKK 205
           N++H  D          E S S+ +  S S    +EK + +  KEK K +++E +K K
Sbjct: 353 NRKHSGDDSFD------EGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPK 404



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 15/60 (25%), Positives = 33/60 (55%)

Query: 147 DNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
           D+++  K    ++ ++   D + DE   S S SE +    +++K+E    ++KEK K+++
Sbjct: 340 DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEE 399



 Score = 28.1 bits (61), Expect = 6.2
 Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 152 EKDVRIQQLKQLLEDSTSDE-DRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHK 210
           EK+ +    K+  + S  D  D  S S SE + +  + +++++  +  KEK+K K+ + +
Sbjct: 342 EKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWE 401

Query: 211 SSKSNEG 217
             K   G
Sbjct: 402 KPKDAAG 408


>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
          Length = 876

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 6/76 (7%)

Query: 147 DNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
           + K ++KD + +  KQ   DS++D D++  S  +G     K++KKE  +K  K+  KK+ 
Sbjct: 299 ERKTNDKDEKKEDGKQAENDSSND-DKTKKSEGDG----DKEEKKEDSEKEAKKSSKKRN 353

Query: 207 RKHKSSKS-NEGSDSE 221
           RKH    S +EGS SE
Sbjct: 354 RKHSGDDSFDEGSVSE 369



 Score = 30.0 bits (66), Expect = 1.6
 Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 147 DNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206
           D+++  K    ++ ++   D + DE   S S SE  E  + +++KE+ ++  KEK+K K+
Sbjct: 340 DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES-ESGQAEEEKEEAEEALKEKEKPKE 398

Query: 207 RKHKSSKSNEG 217
            + +  K   G
Sbjct: 399 EEWEKPKDAAG 409


>gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens]
          Length = 920

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 5/66 (7%)

Query: 152 EKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKS 211
           E D+R+Q  + L  DS  D D +  + ++   KH+K+K     K+RK++K     R+  S
Sbjct: 551 ESDLRLQNCESLTSDSAKDSDSAGEAGAQASSKHQKRK-----KRRKRQKGGSASRRRLS 605

Query: 212 SKSNEG 217
           S S+ G
Sbjct: 606 SASSPG 611


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,891,235
Number of Sequences: 37866
Number of extensions: 603952
Number of successful extensions: 22455
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 767
Number of HSP's successfully gapped in prelim test: 284
Number of HSP's that attempted gapping in prelim test: 7605
Number of HSP's gapped (non-prelim): 8214
length of query: 221
length of database: 18,247,518
effective HSP length: 98
effective length of query: 123
effective length of database: 14,536,650
effective search space: 1788007950
effective search space used: 1788007950
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.