Search of human proteins with 12669909

Search of human proteins with 12669909

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12669909 acyl-CoA synthetase long-chain family member 4
isoform 2 [Homo sapiens]
         (711 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo...  1444   0.0  
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor...  1365   0.0  
gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo...   970   0.0  
gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo...   970   0.0  
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo...   315   1e-85
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo...   315   1e-85
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo...   315   1e-85
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo...   310   2e-84
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo...   306   6e-83
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo...   305   7e-83
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]    149   7e-36
gi|27477105 lipidosin [Homo sapiens]                                  135   2e-31
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]        63   1e-09
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]        63   1e-09
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]        59   2e-08
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H...    47   8e-05
gi|227499619 solute carrier family 27 (fatty acid transporter), ...    45   3e-04
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H...    41   0.004
gi|13325057 solute carrier family 27 (fatty acid transporter), m...    40   0.006
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom...    40   0.006
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo...    39   0.022
gi|40807357 solute carrier family 27 (fatty acid transporter), m...    39   0.022
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]           39   0.022
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s...    38   0.037
gi|38524616 solute carrier family 27, member 1 [Homo sapiens]          36   0.11 
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso...    34   0.54 
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H...    33   0.70 
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]           33   1.2  
gi|62955829 hypothetical protein LOC90871 [Homo sapiens]               32   2.0  
gi|227499621 solute carrier family 27 (fatty acid transporter), ...    32   2.7  

>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
           2 [Homo sapiens]
          Length = 711

 Score = 1444 bits (3739), Expect = 0.0
 Identities = 711/711 (100%), Positives = 711/711 (100%)

Query: 1   MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYR 60
           MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYR
Sbjct: 1   MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYR 60

Query: 61  SVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLIL 120
           SVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLIL
Sbjct: 61  SVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLIL 120

Query: 121 GNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           GNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL
Sbjct: 121 GNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180

Query: 181 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPE 240
           YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPE
Sbjct: 181 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPE 240

Query: 241 GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMT 300
           GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMT
Sbjct: 241 GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMT 300

Query: 301 GQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSK 360
           GQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSK
Sbjct: 301 GQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSK 360

Query: 361 GDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLC 420
           GDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLC
Sbjct: 361 GDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLC 420

Query: 421 NLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEV 480
           NLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEV
Sbjct: 421 NLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEV 480

Query: 481 TDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAED 540
           TDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAED
Sbjct: 481 TDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAED 540

Query: 541 YSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDN 600
           YSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDN
Sbjct: 541 YSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDN 600

Query: 601 ICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAM 660
           ICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAM
Sbjct: 601 ICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAM 660

Query: 661 KLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK 711
           KLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK
Sbjct: 661 KLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK 711


>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
           [Homo sapiens]
          Length = 670

 Score = 1365 bits (3533), Expect = 0.0
 Identities = 670/670 (100%), Positives = 670/670 (100%)

Query: 42  MAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREI 101
           MAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREI
Sbjct: 1   MAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREI 60

Query: 102 LSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRA 161
           LSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRA
Sbjct: 61  LSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRA 120

Query: 162 EWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISC 221
           EWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISC
Sbjct: 121 EWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISC 180

Query: 222 VKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGS 281
           VKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGS
Sbjct: 181 VKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGS 240

Query: 282 TGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIG 341
           TGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIG
Sbjct: 241 TGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIG 300

Query: 342 YSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFK 401
           YSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFK
Sbjct: 301 YSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFK 360

Query: 402 IGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP 461
           IGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP
Sbjct: 361 IGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP 420

Query: 462 IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVI 521
           IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVI
Sbjct: 421 IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVI 480

Query: 522 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 581
           GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE
Sbjct: 481 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 540

Query: 582 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 641
           YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN
Sbjct: 541 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 600

Query: 642 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 701
           NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL
Sbjct: 601 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 660

Query: 702 KDIERMYGGK 711
           KDIERMYGGK
Sbjct: 661 KDIERMYGGK 670


>gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo
           sapiens]
          Length = 720

 Score =  970 bits (2508), Expect = 0.0
 Identities = 466/711 (65%), Positives = 573/711 (80%), Gaps = 2/711 (0%)

Query: 1   MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYR 60
           MKLK  +  I+L  +H LI++Y+ L +IP+YF + ++++ +   RIKAKP + KP S YR
Sbjct: 12  MKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKS--NRIKAKPVNSKPDSAYR 69

Query: 61  SVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLIL 120
           SV   D LA +  PG DTLDK+F +A +KF  K  LGTRE+L+EE+E+QPNGK+FKK+IL
Sbjct: 70  SVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKIFKKVIL 129

Query: 121 GNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           G Y W++Y +V  R  NFG+GL  LG KPK  IAIFCETRAEWMIAAQ CF YNF LVTL
Sbjct: 130 GQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189

Query: 181 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPE 240
           YATLG  A+VH LNE+E + +ITS ELL++KLK  +  +  ++HII VD K    +E+P+
Sbjct: 190 YATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPK 249

Query: 241 GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMT 300
           G  +H+M +VE LG+       P S+P PSD+A++MYTSGSTG PKGVM+ HSN+IAG+T
Sbjct: 250 GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGIT 309

Query: 301 GQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSK 360
           G  ERIP LG +D YIGYLPLAHVLEL+AE+ C ++GCRIGYSSP TL+DQSSKIKKGSK
Sbjct: 310 GMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSK 369

Query: 361 GDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLC 420
           GD ++LKPTLMAAVPEIMDRIYKNVM+KV EM+  Q+ LF + Y+YK+EQI KG + PLC
Sbjct: 370 GDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLC 429

Query: 421 NLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEV 480
           +  +F+KV++LLGGN+R++L GGAPLS  T RFMN+CFCCP+GQGYGLTES GAGT++EV
Sbjct: 430 DSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEV 489

Query: 481 TDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAED 540
            DY TGRVGAPL+CCEIKLK+W+EGGY   DKP+PRGEI+IGGQ+++MGY+KNE KT  D
Sbjct: 490 WDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKAD 549

Query: 541 YSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDN 600
           +  DENGQRW CTGDIGEF PDGCL+IIDRKKDLVKLQAGEYVSLGKVEAALKN PL+DN
Sbjct: 550 FFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDN 609

Query: 601 ICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAM 660
           ICA+A S  SYVI FVVPNQK LT LA++KG++GTW ++CN+  ME E+LK + EAA + 
Sbjct: 610 ICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLKVLSEAAISA 669

Query: 661 KLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK 711
            LE+FEIP+K+RLSPEPWTPETGLVTDAFKLKRKEL+ HY  DIERMYG K
Sbjct: 670 SLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK 720


>gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo
           sapiens]
          Length = 720

 Score =  970 bits (2508), Expect = 0.0
 Identities = 466/711 (65%), Positives = 573/711 (80%), Gaps = 2/711 (0%)

Query: 1   MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYR 60
           MKLK  +  I+L  +H LI++Y+ L +IP+YF + ++++ +   RIKAKP + KP S YR
Sbjct: 12  MKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKS--NRIKAKPVNSKPDSAYR 69

Query: 61  SVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLIL 120
           SV   D LA +  PG DTLDK+F +A +KF  K  LGTRE+L+EE+E+QPNGK+FKK+IL
Sbjct: 70  SVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKIFKKVIL 129

Query: 121 GNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           G Y W++Y +V  R  NFG+GL  LG KPK  IAIFCETRAEWMIAAQ CF YNF LVTL
Sbjct: 130 GQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189

Query: 181 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPE 240
           YATLG  A+VH LNE+E + +ITS ELL++KLK  +  +  ++HII VD K    +E+P+
Sbjct: 190 YATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPK 249

Query: 241 GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMT 300
           G  +H+M +VE LG+       P S+P PSD+A++MYTSGSTG PKGVM+ HSN+IAG+T
Sbjct: 250 GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGIT 309

Query: 301 GQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSK 360
           G  ERIP LG +D YIGYLPLAHVLEL+AE+ C ++GCRIGYSSP TL+DQSSKIKKGSK
Sbjct: 310 GMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSK 369

Query: 361 GDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLC 420
           GD ++LKPTLMAAVPEIMDRIYKNVM+KV EM+  Q+ LF + Y+YK+EQI KG + PLC
Sbjct: 370 GDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLC 429

Query: 421 NLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEV 480
           +  +F+KV++LLGGN+R++L GGAPLS  T RFMN+CFCCP+GQGYGLTES GAGT++EV
Sbjct: 430 DSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEV 489

Query: 481 TDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAED 540
            DY TGRVGAPL+CCEIKLK+W+EGGY   DKP+PRGEI+IGGQ+++MGY+KNE KT  D
Sbjct: 490 WDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKAD 549

Query: 541 YSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDN 600
           +  DENGQRW CTGDIGEF PDGCL+IIDRKKDLVKLQAGEYVSLGKVEAALKN PL+DN
Sbjct: 550 FFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDN 609

Query: 601 ICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAM 660
           ICA+A S  SYVI FVVPNQK LT LA++KG++GTW ++CN+  ME E+LK + EAA + 
Sbjct: 610 ICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLKVLSEAAISA 669

Query: 661 KLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK 711
            LE+FEIP+K+RLSPEPWTPETGLVTDAFKLKRKEL+ HY  DIERMYG K
Sbjct: 670 SLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK 720


>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score =  315 bits (806), Expect = 1e-85
 Identities = 203/607 (33%), Positives = 322/607 (53%), Gaps = 52/607 (8%)

Query: 123 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           Y+W++Y +V+ R    GS L   G K  P   + IF + R EW+I+   C+ Y+   V L
Sbjct: 103 YRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPL 162

Query: 181 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCV--------KHIIYVD--N 230
           Y TLG EA+VH +N+++ + +I          + AL+ I  V        K II +D  +
Sbjct: 163 YDTLGPEAIVHIVNKADIAMVICDTP------QKALVLIGNVEKGFTPSLKVIILMDPFD 216

Query: 231 KAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 290
             + +     G EI S+   E LG       +PPS   P D++++ +TSG+TG PKG M+
Sbjct: 217 DDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPS---PEDLSVICFTSGTTGDPKGAMI 273

Query: 291 HHSNLIAGMTG--QC-ERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 345
            H N+++      +C E      P D  I YLPLAH+ E   +   ++ G R+G+     
Sbjct: 274 THQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDI 333

Query: 346 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 405
             L+D           D   LKPTL  AVP +++RIY  V ++ +    ++K L K+   
Sbjct: 334 RLLAD-----------DMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP--LKKFLLKLAVS 380

Query: 406 YKLEQIKKG---YDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPI 462
            K ++++KG   +D+   + L+F K++  LGG VR++++G AP+S     F      C +
Sbjct: 381 SKFKELQKGIIRHDS-FWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQV 439

Query: 463 GQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGY-TINDKPNPRGEIVI 521
            + YG TE  G  T T   D+T+G VG PL C  +KL+D  +  Y T+N++    GE+ I
Sbjct: 440 YEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNE----GEVCI 495

Query: 522 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 581
            G N+  GY K+ EKT E  ++D +G  W  TGDIG + P+G L+IIDRKK++ KL  GE
Sbjct: 496 KGTNVFKGYLKDPEKTQE--ALDSDG--WLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGE 551

Query: 582 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 641
           Y++  K+E        +  I    +S +S ++  VVP+   L   A + GV+G++ ++C 
Sbjct: 552 YIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQ 611

Query: 642 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 701
           N  +   IL+++++      L+ FE    + L PEP++ E GL+T   K KR EL  ++ 
Sbjct: 612 NQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKYFR 671

Query: 702 KDIERMY 708
             I+ +Y
Sbjct: 672 TQIDSLY 678


>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score =  315 bits (806), Expect = 1e-85
 Identities = 203/607 (33%), Positives = 322/607 (53%), Gaps = 52/607 (8%)

Query: 123 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           Y+W++Y +V+ R    GS L   G K  P   + IF + R EW+I+   C+ Y+   V L
Sbjct: 103 YRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPL 162

Query: 181 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCV--------KHIIYVD--N 230
           Y TLG EA+VH +N+++ + +I          + AL+ I  V        K II +D  +
Sbjct: 163 YDTLGPEAIVHIVNKADIAMVICDTP------QKALVLIGNVEKGFTPSLKVIILMDPFD 216

Query: 231 KAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 290
             + +     G EI S+   E LG       +PPS   P D++++ +TSG+TG PKG M+
Sbjct: 217 DDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPS---PEDLSVICFTSGTTGDPKGAMI 273

Query: 291 HHSNLIAGMTG--QC-ERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 345
            H N+++      +C E      P D  I YLPLAH+ E   +   ++ G R+G+     
Sbjct: 274 THQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDI 333

Query: 346 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 405
             L+D           D   LKPTL  AVP +++RIY  V ++ +    ++K L K+   
Sbjct: 334 RLLAD-----------DMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP--LKKFLLKLAVS 380

Query: 406 YKLEQIKKG---YDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPI 462
            K ++++KG   +D+   + L+F K++  LGG VR++++G AP+S     F      C +
Sbjct: 381 SKFKELQKGIIRHDS-FWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQV 439

Query: 463 GQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGY-TINDKPNPRGEIVI 521
            + YG TE  G  T T   D+T+G VG PL C  +KL+D  +  Y T+N++    GE+ I
Sbjct: 440 YEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNE----GEVCI 495

Query: 522 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 581
            G N+  GY K+ EKT E  ++D +G  W  TGDIG + P+G L+IIDRKK++ KL  GE
Sbjct: 496 KGTNVFKGYLKDPEKTQE--ALDSDG--WLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGE 551

Query: 582 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 641
           Y++  K+E        +  I    +S +S ++  VVP+   L   A + GV+G++ ++C 
Sbjct: 552 YIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQ 611

Query: 642 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 701
           N  +   IL+++++      L+ FE    + L PEP++ E GL+T   K KR EL  ++ 
Sbjct: 612 NQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKYFR 671

Query: 702 KDIERMY 708
             I+ +Y
Sbjct: 672 TQIDSLY 678


>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
           a [Homo sapiens]
          Length = 739

 Score =  315 bits (806), Expect = 1e-85
 Identities = 203/607 (33%), Positives = 322/607 (53%), Gaps = 52/607 (8%)

Query: 123 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           Y+W++Y +V+ R    GS L   G K  P   + IF + R EW+I+   C+ Y+   V L
Sbjct: 159 YRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPL 218

Query: 181 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCV--------KHIIYVD--N 230
           Y TLG EA+VH +N+++ + +I          + AL+ I  V        K II +D  +
Sbjct: 219 YDTLGPEAIVHIVNKADIAMVICDTP------QKALVLIGNVEKGFTPSLKVIILMDPFD 272

Query: 231 KAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 290
             + +     G EI S+   E LG       +PPS   P D++++ +TSG+TG PKG M+
Sbjct: 273 DDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPS---PEDLSVICFTSGTTGDPKGAMI 329

Query: 291 HHSNLIAGMTG--QC-ERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 345
            H N+++      +C E      P D  I YLPLAH+ E   +   ++ G R+G+     
Sbjct: 330 THQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDI 389

Query: 346 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 405
             L+D           D   LKPTL  AVP +++RIY  V ++ +    ++K L K+   
Sbjct: 390 RLLAD-----------DMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP--LKKFLLKLAVS 436

Query: 406 YKLEQIKKG---YDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPI 462
            K ++++KG   +D+   + L+F K++  LGG VR++++G AP+S     F      C +
Sbjct: 437 SKFKELQKGIIRHDS-FWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQV 495

Query: 463 GQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGY-TINDKPNPRGEIVI 521
            + YG TE  G  T T   D+T+G VG PL C  +KL+D  +  Y T+N++    GE+ I
Sbjct: 496 YEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNE----GEVCI 551

Query: 522 GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE 581
            G N+  GY K+ EKT E  ++D +G  W  TGDIG + P+G L+IIDRKK++ KL  GE
Sbjct: 552 KGTNVFKGYLKDPEKTQE--ALDSDG--WLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGE 607

Query: 582 YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN 641
           Y++  K+E        +  I    +S +S ++  VVP+   L   A + GV+G++ ++C 
Sbjct: 608 YIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQ 667

Query: 642 NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL 701
           N  +   IL+++++      L+ FE    + L PEP++ E GL+T   K KR EL  ++ 
Sbjct: 668 NQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKYFR 727

Query: 702 KDIERMY 708
             I+ +Y
Sbjct: 728 TQIDSLY 734


>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
           sapiens]
          Length = 698

 Score =  310 bits (795), Expect = 2e-84
 Identities = 199/605 (32%), Positives = 316/605 (52%), Gaps = 48/605 (7%)

Query: 123 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           Y+W++Y +V       GS L   G K  P   I IF + R EW+I  Q CF Y+  +V L
Sbjct: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177

Query: 181 YATLGKEAVVHGLNESEASYLITS--------VELLESKLKTALLDISCVKHIIYVDNKA 232
           Y TLG EA+ + +N++E S +           +E +E+KL      I  +K I+ +D   
Sbjct: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKL------IPGLKIIVVMDAYG 231

Query: 233 INKAEYPE--GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 290
               E  +  G E+ SM+++E+LG         P  P P D+A++ +TSG+TG PKG M+
Sbjct: 232 SELVERGQRCGVEVTSMKAMEDLGRANRR---KPKPPAPEDLAVICFTSGTTGNPKGAMV 288

Query: 291 HHSNLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 345
            H N+++  +      E      P DT I +LPLAH+ E   E     +G +IG+     
Sbjct: 289 THRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDI 348

Query: 346 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 405
             L D           D  VL+PT+   VP +++R++  +    Q    +++ L      
Sbjct: 349 RLLMD-----------DLKVLQPTVFPVVPRLLNRMFDRIFG--QANTTLKRWLLDFASK 395

Query: 406 YKLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIG 463
            K  +++ G   +  L + L+F KV++ LGG VR+M++G AP+S     F+     C   
Sbjct: 396 RKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFY 455

Query: 464 QGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGG 523
           +GYG TE      +T   D+T G VGAP+ C  IKL D +E  Y   +     GE+ + G
Sbjct: 456 EGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKG 512

Query: 524 QNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYV 583
            N+  GY K+  KTAE  ++D++G  W  TGDIG++ P+G L+IIDRKK + KL  GEY+
Sbjct: 513 PNVFQGYLKDPAKTAE--ALDKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYI 568

Query: 584 SLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNP 643
           +  K+E        +  +    +S Q+++I+ VVP+ + L   AQ++G EG++ ++C N 
Sbjct: 569 APEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNK 628

Query: 644 AMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKD 703
            ++  IL+++        L+ FE    + L PE ++ + GL+T   K KR ELRN++   
Sbjct: 629 DVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQ 688

Query: 704 IERMY 708
           I+ +Y
Sbjct: 689 IDDLY 693


>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
           a [Homo sapiens]
          Length = 722

 Score =  306 bits (783), Expect = 6e-83
 Identities = 200/604 (33%), Positives = 313/604 (51%), Gaps = 46/604 (7%)

Query: 123 YKWMNYLEVNRRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           Y+W++Y EV  R    GSGL     K      I +F + R EW+I    C+ Y+  +V L
Sbjct: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202

Query: 181 YATLGKEAVVHGLNESEASYLIT-----SVELLESKLKTALLDISCVKHIIYVD--NKAI 233
           Y TLG  A+ + +N ++ S +I      +V LLE   +    +   +K II +D   +A+
Sbjct: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK---ETPGLKLIILMDPFEEAL 259

Query: 234 NKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 293
            +     G  I SMQ+VE+ G       +PP    P D++IV +TSG+TG PKG M+ H 
Sbjct: 260 KERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ---PDDLSIVCFTSGTTGNPKGAMLTHG 316

Query: 294 NLIAGMTG-----QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSPL 346
           N++A  +G     + +  P     D +I YLPLAH+ E   +   + +G R+G+      
Sbjct: 317 NVVADFSGFLKVTESQWAPTCA--DVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIR 374

Query: 347 TLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDY 406
            LSD           D   L PT+   VP +++R+Y  + S  Q    +++ L +     
Sbjct: 375 LLSD-----------DMKALCPTIFPVVPRLLNRMYDKIFS--QANTPLKRWLLEFAAKR 421

Query: 407 KLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQ 464
           K  +++ G   +  + + L F K++A LGG VRM+++G AP SP    F+     C + +
Sbjct: 422 KQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE 481

Query: 465 GYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQ 524
           GYG TE     T T   D+T+G VGAPL C  IKL D +E  Y         GEI + G 
Sbjct: 482 GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWAC---KGEGEICVRGP 538

Query: 525 NISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVS 584
           N+  GY K+ ++T E  ++D +G  W  TGDIG++ P G L+IIDRKK + KL  GEYV+
Sbjct: 539 NVFKGYLKDPDRTKE--ALDSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVA 594

Query: 585 LGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPA 644
             K+E        +  I     S +++++  VVP+ + +   AQ++G+EGT+ D+C N  
Sbjct: 595 PEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKD 654

Query: 645 MEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDI 704
           ++  IL+++        L  FE    + +  + ++ + GL+T   K KR ELR ++ K I
Sbjct: 655 LKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQI 714

Query: 705 ERMY 708
           E +Y
Sbjct: 715 EELY 718


>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
           b [Homo sapiens]
          Length = 722

 Score =  305 bits (782), Expect = 7e-83
 Identities = 199/602 (33%), Positives = 312/602 (51%), Gaps = 42/602 (6%)

Query: 123 YKWMNYLEVNRRVNNFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           Y+W++Y EV  R    GSGL     K      I +F + R EW+I    C+ Y+  +V L
Sbjct: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202

Query: 181 YATLGKEAVVHGLNESEASYLIT-----SVELLESKLKTALLDISCVKHIIYVD--NKAI 233
           Y TLG  A+ + +N ++ S +I      +V LLE   +    +   +K II +D   +A+
Sbjct: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK---ETPGLKLIILMDPFEEAL 259

Query: 234 NKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 293
            +     G  I SMQ+VE+ G       +PP    P D++IV +TSG+TG PKG M+ H 
Sbjct: 260 KERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ---PDDLSIVCFTSGTTGNPKGAMLTHG 316

Query: 294 NLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSPLTL 348
           N++A  +G     E++      D  I +LPLAH+ E   +   + +G R+G+       L
Sbjct: 317 NVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLL 376

Query: 349 SDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKL 408
           SD           D   L PT+   VP +++R+Y  + S  Q    +++ L +     K 
Sbjct: 377 SD-----------DMKALCPTIFPVVPRLLNRMYDKIFS--QANTPLKRWLLEFAAKRKQ 423

Query: 409 EQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGY 466
            +++ G   +  + + L F K++A LGG VRM+++G AP SP    F+     C + +GY
Sbjct: 424 AEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGY 483

Query: 467 GLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNI 526
           G TE     T T   D+T+G VGAPL C  IKL D +E  Y         GEI + G N+
Sbjct: 484 GQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWAC---KGEGEICVRGPNV 540

Query: 527 SMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLG 586
             GY K+ ++T E  ++D +G  W  TGDIG++ P G L+IIDRKK + KL  GEYV+  
Sbjct: 541 FKGYLKDPDRTKE--ALDSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPE 596

Query: 587 KVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAME 646
           K+E        +  I     S +++++  VVP+ + +   AQ++G+EGT+ D+C N  ++
Sbjct: 597 KIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLK 656

Query: 647 AEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIER 706
             IL+++        L  FE    + +  + ++ + GL+T   K KR ELR ++ K IE 
Sbjct: 657 KAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEE 716

Query: 707 MY 708
           +Y
Sbjct: 717 LY 718


>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
          Length = 666

 Score =  149 bits (377), Expect = 7e-36
 Identities = 168/669 (25%), Positives = 289/669 (43%), Gaps = 93/669 (13%)

Query: 78  TLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNN 137
           T+ + F  +V++FG   +L ++           NGK ++ L      +  Y E  R+   
Sbjct: 52  TIPEFFRESVNRFGTYPALASK-----------NGKKWEIL-----NFNQYYEACRKA-- 93

Query: 138 FGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESE 197
               L  LGL+  + + I     AEW I A          V +YAT   E   + +  ++
Sbjct: 94  -AKSLIKLGLERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAK 152

Query: 198 ASYLIT-SVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSN 256
            + L+  + + L+  L      +  +K II        +    +   ++S     ELG +
Sbjct: 153 VNILLVENDQQLQKILSIPQSSLEPLKAIIQY------RLPMKKNNNLYSWDDFMELGRS 206

Query: 257 PENLGIPP--SRPTPSDMAIVMYTSGSTGRPKGVMMHHSNL--IAGMTGQCERIPGLGPK 312
             +  +         +  A+++YTSG+TG PKGVM+ H N+  IAG   +  ++      
Sbjct: 207 IPDTQLEQVIESQKANQCAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKL--TDKH 264

Query: 313 DTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMA 372
           +T + YLPL+H+    A++       +IG    LT   Q+  +K         +KPT+  
Sbjct: 265 ETVVSYLPLSHI---AAQMMDIWVPIKIG---ALTYFAQADALKGTLVSTLKEVKPTVFI 318

Query: 373 AVPEIMDRIYKNVMSKVQEMNYIQKTLF----KIGYDYKLEQIKKGYDAP----LCNLLL 424
            VP+I ++I++ V     +   ++K  F     IG+    +++   Y+ P    +   L+
Sbjct: 319 GVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYRMAKTLV 378

Query: 425 FKKVKALLG-GNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDY 483
           F KVK  LG  +    +SG APL+ +T  F  +    PIG+ YGL+ES G  T++   +Y
Sbjct: 379 FSKVKTSLGLDHCHSFISGTAPLNQETAEFF-LSLDIPIGELYGLSESSGPHTISNQNNY 437

Query: 484 TTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSV 543
                G  L  C+  L    + G          GEI + G++I MGY ++E +T E  ++
Sbjct: 438 RLLSCGKILTGCKNMLFQQNKDGI---------GEICLWGRHIFMGYLESETETTE--AI 486

Query: 544 DENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAAL-KNCPLIDNIC 602
           D+ G  W  +GD+G+    G L +    K+++    GE V    VE  + K  P+I N  
Sbjct: 487 DDEG--WLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISN-- 542

Query: 603 AFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAME------------AEIL 650
           A    D+   +S +      LTL  +   + G  +D  N  A+              EI+
Sbjct: 543 AMLVGDKLKFLSML------LTLKCEMNQMSGEPLDKLNFEAINFCRGLGSQASTVTEIV 596

Query: 651 KE--------IREAANAMKLERFEIPIKVR---LSPEPWTPETGLVTDAFKLKRKELRNH 699
           K+        I++  NA+  E      ++    +  + ++   G +    KLKR  +   
Sbjct: 597 KQQDPLVYKAIQQGINAVNQEAMNNAQRIEKWVILEKDFSIYGGELGPMMKLKRHFVAQK 656

Query: 700 YLKDIERMY 708
           Y K I+ MY
Sbjct: 657 YKKQIDHMY 665


>gi|27477105 lipidosin [Homo sapiens]
          Length = 724

 Score =  135 bits (339), Expect = 2e-31
 Identities = 133/555 (23%), Positives = 230/555 (41%), Gaps = 62/555 (11%)

Query: 78  TLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNN 137
           T+ ++F  A+ K+G   +LG                 FK+     ++ ++Y +       
Sbjct: 104 TVHRMFYEALDKYGDLIALG-----------------FKRQ--DKWEHISYSQYYLLARR 144

Query: 138 FGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESE 197
              G   LGLK  +++AI      EW  +A         +  +Y T   EA  +   +  
Sbjct: 145 AAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCC 204

Query: 198 ASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSN- 256
           A+ ++   +    K+      +  +K ++       NK        +++M+   ELG+  
Sbjct: 205 ANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPNKMA-----NVYTMEEFMELGNEV 259

Query: 257 -PENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNL--IAGMTGQCERI-PGLGPK 312
             E L        P+   +++YTSG+TG PKGVM+   N+   A    Q   I P    +
Sbjct: 260 PEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIRPAEVQQ 319

Query: 313 DTYIGYLPLAHVLELTAEI-SCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLM 371
           +  + YLPL+H+     ++ +   +G ++ ++ P         +K         ++PT  
Sbjct: 320 EVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEP-------DALKGSLVNTLREVEPTSH 372

Query: 372 AAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQ-------IKKGYDAPLCNLLL 424
             VP + ++I + +     +  +I++ +        LEQ         K +   L + L+
Sbjct: 373 MGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADYLV 432

Query: 425 FKKVKALLG-GNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDY 483
             KV+  LG    +    G AP+  +T  F  +     +  GYGL+E+ G   ++   +Y
Sbjct: 433 LAKVRQALGFAKCQKNFYGAAPMMAETQHFF-LGLNIRLYAGYGLSETSGPHFMSSPYNY 491

Query: 484 TTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSV 543
                G  +  C +KL         +N      GEI + G+ I MGY   E+KT E  ++
Sbjct: 492 RLYSSGKLVPGCRVKL---------VNQDAEGIGEICLWGRTIFMGYLNMEDKTCE--AI 540

Query: 544 DENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALK-NCPLIDNIC 602
           DE G  W  TGD G    DG L I  R K+L+    GE V    +E A+K   P+I N  
Sbjct: 541 DEEG--WLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISN-- 596

Query: 603 AFAKSDQSYVISFVV 617
           A    DQ   +S ++
Sbjct: 597 AMLIGDQRKFLSMLL 611


>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 111/479 (23%), Positives = 188/479 (39%), Gaps = 84/479 (17%)

Query: 153 IAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKL 212
           ++  C   A +++A    +      V LY       + + + +S++S ++ S E LE   
Sbjct: 98  VSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLEL-- 155

Query: 213 KTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDM 272
                 +S V   + V    +  A Y    E  +   V E G   +              
Sbjct: 156 ------LSPVVRKLGVPLLPLTPAIYTGAVEEPAEVPVPEQGWRNKG------------- 196

Query: 273 AIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEIS 332
           A+++YTSG+TGRPKGV+  H N+ A +TG   +       D  +  LPL HV  +   + 
Sbjct: 197 AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW-AWTKDDVILHVLPLHHVHGVVNALL 255

Query: 333 CFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEM 392
           C           PL +      + + S     V +  L +  P I      NV   V  +
Sbjct: 256 C-----------PLWVGATCVMMPEFSPQQ--VWEKFLSSETPRI------NVFMAVPTI 296

Query: 393 NYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLS-PQTH 451
                      Y   +E   + +  P     L    +A+    +R+M+SG A L  P   
Sbjct: 297 -----------YTKLMEYYDRHFTQPHAQDFL----RAVCEEKIRLMVSGSAALPLPVLE 341

Query: 452 RFMNVCFCCPIGQGYGLTE--SCGAGTVTEVTDYTTGRVGAPLICCEIKL----KDWQEG 505
           ++ N+     + + YG+TE     +G +T       G VG PL   ++++       +  
Sbjct: 342 KWKNITGHTLL-ERYGMTEIGMALSGPLTTAV-RLPGSVGTPLPGVQVRIVSENPQREAC 399

Query: 506 GYTINDKPNPR------------GEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCT 553
            YTI+ + + R            GE+++ G ++   Y+   E+T   +++D     WF T
Sbjct: 400 SYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLD----GWFKT 455

Query: 554 GDIGEFHPDGCLQIIDRKK-DLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSY 611
           GD   F  DG   I  R   D++K   G  VS  +VE  L   P I ++      D ++
Sbjct: 456 GDTVVF-KDGQYWIRGRTSVDIIK-TGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW 512


>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 111/479 (23%), Positives = 188/479 (39%), Gaps = 84/479 (17%)

Query: 153 IAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKL 212
           ++  C   A +++A    +      V LY       + + + +S++S ++ S E LE   
Sbjct: 98  VSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLEL-- 155

Query: 213 KTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDM 272
                 +S V   + V    +  A Y    E  +   V E G   +              
Sbjct: 156 ------LSPVVRKLGVPLLPLTPAIYTGAVEEPAEVPVPEQGWRNKG------------- 196

Query: 273 AIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEIS 332
           A+++YTSG+TGRPKGV+  H N+ A +TG   +       D  +  LPL HV  +   + 
Sbjct: 197 AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW-AWTKDDVILHVLPLHHVHGVVNALL 255

Query: 333 CFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEM 392
           C           PL +      + + S     V +  L +  P I      NV   V  +
Sbjct: 256 C-----------PLWVGATCVMMPEFSPQQ--VWEKFLSSETPRI------NVFMAVPTI 296

Query: 393 NYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLS-PQTH 451
                      Y   +E   + +  P     L    +A+    +R+M+SG A L  P   
Sbjct: 297 -----------YTKLMEYYDRHFTQPHAQDFL----RAVCEEKIRLMVSGSAALPLPVLE 341

Query: 452 RFMNVCFCCPIGQGYGLTE--SCGAGTVTEVTDYTTGRVGAPLICCEIKL----KDWQEG 505
           ++ N+     + + YG+TE     +G +T       G VG PL   ++++       +  
Sbjct: 342 KWKNITGHTLL-ERYGMTEIGMALSGPLTTAV-RLPGSVGTPLPGVQVRIVSENPQREAC 399

Query: 506 GYTINDKPNPR------------GEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCT 553
            YTI+ + + R            GE+++ G ++   Y+   E+T   +++D     WF T
Sbjct: 400 SYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLD----GWFKT 455

Query: 554 GDIGEFHPDGCLQIIDRKK-DLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSY 611
           GD   F  DG   I  R   D++K   G  VS  +VE  L   P I ++      D ++
Sbjct: 456 GDTVVF-KDGQYWIRGRTSVDIIK-TGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW 512


>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
          Length = 615

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 68/335 (20%), Positives = 135/335 (40%), Gaps = 64/335 (19%)

Query: 275 VMYTSGSTGRPKGVMMHHSNLI--AGMTGQCERIPGLGPKDT-YIGYLPLAHVL-ELTAE 330
           + +TSG+TG PKG  + H N++  + + G+  ++    P+    I   PL H L  +   
Sbjct: 260 IQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGT 319

Query: 331 ISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQ 390
           + C  YG  +  +SP+    ++ +     +G      PT+           + +++++  
Sbjct: 320 MMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTM-----------FVDILNQPD 368

Query: 391 EMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQT 450
             +Y                                 +  + GG +      G+P  P+ 
Sbjct: 369 FSSY--------------------------------DISTMCGGVI-----AGSPAPPEL 391

Query: 451 HR-FMNVCFCCPIGQGYGLTESCG---AGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGG 506
            R  +N      +   YG TE+     A    +  +     VG  +   E ++ + + G 
Sbjct: 392 IRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGT 451

Query: 507 YTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQ 566
                K N  GE+ I G  + +GY+   +KT E  +VD++  +W+ TGD+   +  G  +
Sbjct: 452 LA---KLNTPGELCIRGYCVMLGYWGEPQKTEE--AVDQD--KWYWTGDVATMNEQGFCK 504

Query: 567 IIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNI 601
           I+ R KD++ ++ GE +   ++E      P +  +
Sbjct: 505 IVGRSKDMI-IRGGENIYPAELEDFFHTHPKVQEV 538


>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
           sapiens]
          Length = 580

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 56/222 (25%), Positives = 94/222 (42%), Gaps = 25/222 (11%)

Query: 422 LLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVT 481
           +L+ K +K     ++R  L+GG PL+P+      V     + +GYG TE        +  
Sbjct: 326 MLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQ 385

Query: 482 DYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQN-----ISMGYFKNEEK 536
           +   G +G  ++  ++++ D  E G  +   P   GEI +  +          Y  N +K
Sbjct: 386 EIKPGSMGKGMLPYDVQIID--ENGNVL--PPGKEGEIALRLKPTRPFCFFSKYVDNPQK 441

Query: 537 TAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCP 596
           TA     D     ++ TGD G    DG    + R  D++ + +G  +   +VE+AL   P
Sbjct: 442 TAATIRGD-----FYVTGDRGVMDSDGYFWFVGRADDVI-ISSGYRIGPFEVESALIEHP 495

Query: 597 LIDNICAFAKSDQ---SYVISFVV-------PNQKRLTLLAQ 628
            +      +  DQ     V +FVV        N ++LTL  Q
Sbjct: 496 AVVESAVVSSPDQIRGEVVKAFVVLAAPFKSYNPEKLTLELQ 537



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 17/157 (10%)

Query: 146 GLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSV 205
           GL+  + +A+      EW +    C +     +     L  + +++ L  S+A  ++ S 
Sbjct: 110 GLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASE 169

Query: 206 ELLESKLKTALLDISCVKHIIYVDNKAINK-AEYPEGFEIHSMQ-SVEELGSNPENLGIP 263
           E+  + +++ +L+   +K  + V  ++ N    + E F+  S + S  E GS        
Sbjct: 170 EVAPA-VESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEHSCVETGSQ------- 221

Query: 264 PSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMT 300
                  +   + +TSG+TG PK      S+L  G T
Sbjct: 222 -------EPMTIYFTSGTTGFPKMAQHSQSSLGIGFT 251


>gi|227499619 solute carrier family 27 (fatty acid transporter),
           member 2 isoform 1 [Homo sapiens]
          Length = 620

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 58/239 (24%), Positives = 98/239 (41%), Gaps = 17/239 (7%)

Query: 116 KKLILGNYKWMNYLEVNRRVNNFGSGL-TALGLKPKNTIAIFCETRAEWMIAAQTCFKYN 174
           K  +L   + + Y +V+RR N     L   LGL+  + +A+       ++       K  
Sbjct: 69  KPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLG 128

Query: 175 FPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAIN 234
             +  L   +  ++++H      A  L+ S EL ++ ++  L  +      IY  ++  N
Sbjct: 129 CAMACLNYNIRAKSLLHCFQCCGAKVLLVSPEL-QAAVEEILPSLKKDDVSIYYVSRTSN 187

Query: 235 KAEYPEGFEIHSMQSVEELGSNPENLGIPPS---RPTPSDMAIVMYTSGSTGRPKGVMMH 291
                +G +   +  V+E+ + P    IP S     T S  A+ +YTSG+TG PK  M+ 
Sbjct: 188 T----DGIDSF-LDKVDEVSTEP----IPESWRSEVTFSTPALYIYTSGTTGLPKAAMIT 238

Query: 292 HSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEI-SCFTYGCRIGYSSPLTLS 349
           H  +  G TG    + GL   D     LP  H   L   I  C   G  +   +  + S
Sbjct: 239 HQRIWYG-TG-LTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSAS 295


>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
           sapiens]
          Length = 577

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 48/204 (23%), Positives = 84/204 (41%), Gaps = 16/204 (7%)

Query: 411 IKKGYDAPLC-NLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLT 469
           IK    AP+   +LL + + +    +++  ++ G  L P+T           I + YG T
Sbjct: 305 IKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRESYGQT 364

Query: 470 ESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQ----- 524
           E+     V++      G +G    C ++++ D  + G  +   P   G+I I  +     
Sbjct: 365 ETGLTCMVSKTMKIKPGYMGTAASCYDVQIID--DKGNVL--PPGTEGDIGIRVKPIRPI 420

Query: 525 NISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVS 584
            I  GY  N +KTA +   D     ++  GD G    DG  Q + R  D++   +G  + 
Sbjct: 421 GIFSGYVDNPDKTAANIRGD-----FWLLGDRGIKDEDGYFQFMGRADDIIN-SSGYRIG 474

Query: 585 LGKVEAALKNCPLIDNICAFAKSD 608
             +VE AL   P +      +  D
Sbjct: 475 PSEVENALMEHPAVVETAVISSPD 498


>gi|13325057 solute carrier family 27 (fatty acid transporter),
           member 5 [Homo sapiens]
          Length = 690

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 12/113 (10%)

Query: 235 KAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDM---------AIVMYTSGSTGRP 285
           +AE    F +        +G+    L   PS P P+D+         A+ +YTSG+TG P
Sbjct: 243 QAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLP 302

Query: 286 KGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEI-SCFTYG 337
           K  ++ H  ++     +   + G    D     LPL HV+ L   I  C   G
Sbjct: 303 KPAILTHERVL--QMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLG 353


>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
           sapiens]
          Length = 689

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 37/173 (21%), Positives = 73/173 (42%), Gaps = 17/173 (9%)

Query: 126 MNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLG 185
           + Y E+        + L   G+   + +AI+       + A   C +       ++A   
Sbjct: 141 ITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFS 200

Query: 186 KEAVVHGLNESEASYLIT--------SVELLESKLKTALLDISCVKHIIYVDNKAINKAE 237
            E++   +N+++   +IT         V  L+  +  A+     V+H++ V ++  NK  
Sbjct: 201 AESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVL-VAHRTDNKVH 259

Query: 238 YPE-GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVM 289
             +    +    + E+    PE++G         DM  ++YTSGSTG PKG++
Sbjct: 260 MGDLDVPLEQEMAKEDPVCAPESMG-------SEDMLFMLYTSGSTGMPKGIV 305


>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
           1 [Homo sapiens]
          Length = 701

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 41/207 (19%), Positives = 78/207 (37%), Gaps = 48/207 (23%)

Query: 121 GNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           G    + Y ++  +V  F + L   G++  + +AI+     E ++A   C +       +
Sbjct: 131 GETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLACARIGALHSIV 190

Query: 181 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPE 240
           +A    E++   + +S  S LIT+      +    L +++         ++A+ K +  +
Sbjct: 191 FAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELA---------DEALQKCQ-EK 240

Query: 241 GFEIHSMQSVEELGSNPENLGIPPSRPTP------------------------------- 269
           GF +     V+ LG     +G   S+  P                               
Sbjct: 241 GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQISWNQGIDLWWHELMQEAGDEC 300

Query: 270 -------SDMAIVMYTSGSTGRPKGVM 289
                   D   ++YTSGSTG+PKGV+
Sbjct: 301 EPEWCDAEDPLFILYTSGSTGKPKGVV 327


>gi|40807357 solute carrier family 27 (fatty acid transporter),
           member 4 [Homo sapiens]
          Length = 643

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 52/198 (26%), Positives = 81/198 (40%), Gaps = 20/198 (10%)

Query: 130 EVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAV 189
           E +  V NF   L A GL   +  AIF E R E++       K       +   L ++A+
Sbjct: 109 EYSSSVANF---LQARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDAL 165

Query: 190 VHGLNESEASYLITSVELLESKLKT-ALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQ 248
           +H L  S A  L+   E+  +  +  A LD S                 +  G    S +
Sbjct: 166 LHCLTTSRARALVFGSEMASAICEVHASLDPSL---------SLFCSGSWEPGAVPPSTE 216

Query: 249 SVEELGSN-PENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNL--IAGMTGQCER 305
            ++ L  + P++L   P +   +D    +YTSG+TG PK  ++ HS    +A +     R
Sbjct: 217 HLDPLLKDAPKHLPSCPDKGF-TDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFR 275

Query: 306 IPGLGPKDTYIGYLPLAH 323
              + P D     LPL H
Sbjct: 276 ---MRPNDIVYDCLPLYH 290


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 49/205 (23%), Positives = 84/205 (40%), Gaps = 18/205 (8%)

Query: 141 GLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASY 200
           G  A  L P  T+A+      E++       K       +   L +  ++H L    A  
Sbjct: 205 GGAAAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARA 264

Query: 201 LITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGF-EIHSMQSVEELGSNPEN 259
           L+ + E LES L+  L  +  +   ++    A     +P G  ++ +  S E  G  P  
Sbjct: 265 LVLAPEFLES-LEPDLPALRAMGLHLW----AAGPGTHPAGISDLLAEVSAEVDGPVPGY 319

Query: 260 LGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCE---RIPGLGPKDTYI 316
           L  P S    +D  + ++TSG+TG PK   + H  ++     QC+   ++ G+  +D   
Sbjct: 320 LSSPQSI---TDTCLYIFTSGTTGLPKAARISHLKIL-----QCQGFYQLCGVHQEDVIY 371

Query: 317 GYLPLAHVL-ELTAEISCFTYGCRI 340
             LPL H+   L   + C   G  +
Sbjct: 372 LALPLYHMSGSLLGIVGCMGIGATV 396


>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
           sapiens]
          Length = 586

 Score = 37.7 bits (86), Expect = 0.037
 Identities = 51/200 (25%), Positives = 78/200 (39%), Gaps = 32/200 (16%)

Query: 435 NVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTES---CGAGTVTEVTDYTTGRVGAP 491
           +++  +S G P++P             I +GYG TE+   CG     ++     G +G P
Sbjct: 345 SLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKP---GSMGKP 401

Query: 492 LICCEIKLKD--------WQEGGYTINDKPN-PRGEIVIGGQNISMGYFKNEEKTAEDYS 542
               ++K+ D         QEG   I   PN P G        +   Y  N  KTA    
Sbjct: 402 SPAFDVKIVDVNGNVLPPGQEGDIGIQVLPNRPFG--------LFTHYVDNPSKTASTLR 453

Query: 543 VDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNIC 602
            +     ++ TGD G    DG    + R  D++ L +G  +   +VE AL   P +    
Sbjct: 454 GN-----FYITGDRGYMDKDGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVAESA 507

Query: 603 AFAKSDQ---SYVISFVVPN 619
             +  D      V +FVV N
Sbjct: 508 VVSSPDPIRGEVVKAFVVLN 527


>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
          Length = 646

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 41/151 (27%), Positives = 62/151 (41%), Gaps = 11/151 (7%)

Query: 145 LGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITS 204
           LG  P + +AIF E R E++       K       L   L +E +   L  S A  LI  
Sbjct: 123 LGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFG 182

Query: 205 VELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGF--EIHSMQSVEELGSNPENLGI 262
            E++      A+ ++S   H+     K  +    PEG   + H +  + +  S      I
Sbjct: 183 GEMV-----AAVAEVS--GHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQI 235

Query: 263 PPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 293
           P       D    +YTSG+TG PK  ++ HS
Sbjct: 236 PSKGM--DDRLFYIYTSGTTGLPKAAIVVHS 264


>gi|253970489 acyl-CoA synthetase short-chain family member 2
           isoform 2 [Homo sapiens]
          Length = 714

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 20/126 (15%)

Query: 166 AAQTCFKYNFPL--VTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVK 223
           A Q C +  FP+    +   LG+  +  G + S++  +  S   ++ KLK          
Sbjct: 233 ALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKLKEK-------- 284

Query: 224 HIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTG 283
                  +   +  + +G ++   + ++E G   E     P      D   ++YTSGSTG
Sbjct: 285 -----SKRVQPQISWNQGIDLWWHELMQEAGDECE-----PEWCDAEDPLFILYTSGSTG 334

Query: 284 RPKGVM 289
           +PKGV+
Sbjct: 335 KPKGVV 340


>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
           sapiens]
          Length = 577

 Score = 33.5 bits (75), Expect = 0.70
 Identities = 37/169 (21%), Positives = 77/169 (45%), Gaps = 19/169 (11%)

Query: 130 EVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAV 189
           ++ RRV N  +     GL+  + +A+      EW + A  C +     +     L  + +
Sbjct: 93  DLTRRVANVFT--QTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDI 150

Query: 190 VHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGF-EIHSMQ 248
           ++ L  S+A  ++T ++ L S++ +       +K  + V + +       EG+ +  S+ 
Sbjct: 151 LYRLQLSKAKGIVT-IDALASEVDSIASQCPSLKTKLLVSDHS------REGWLDFRSLV 203

Query: 249 SVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIA 297
                 ++PE+  +   +    D  ++ +TSG+TG PK  M  HS+ +A
Sbjct: 204 K----SASPEHTCV---KSKTLDPMVIFFTSGTTGFPK--MAKHSHGLA 243


>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
          Length = 1960

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 20/88 (22%), Positives = 33/88 (37%)

Query: 303  CERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGD 362
            C R+ GL         +  +H  E  A + C+  GC   Y  P  +       ++     
Sbjct: 1869 CGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVR 1928

Query: 363  CTVLKPTLMAAVPEIMDRIYKNVMSKVQ 390
            C   KP L   +P + ++  K  +S  Q
Sbjct: 1929 CPKHKPPLPCPLPPLQNKTAKGSLSTEQ 1956


>gi|62955829 hypothetical protein LOC90871 [Homo sapiens]
          Length = 112

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 13/31 (41%), Positives = 17/31 (54%)

Query: 443 GAPLSPQTHRFMNVCFCCPIGQGYGLTESCG 473
           GAP SP  HR +  C+ C +  G GL  + G
Sbjct: 33  GAPTSPAEHRLLKTCWSCRVLSGLGLMGAGG 63


>gi|227499621 solute carrier family 27 (fatty acid transporter),
           member 2 isoform 2 [Homo sapiens]
          Length = 567

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 14/172 (8%)

Query: 116 KKLILGNYKWMNYLEVNRRVNNFGSGL-TALGLKPKNTIAIFCETRAEWMIAAQTCFKYN 174
           K  +L   + + Y +V+RR N     L   LGL+  + +A+       ++       K  
Sbjct: 69  KPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLG 128

Query: 175 FPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAIN 234
             +  L   +  ++++H      A  L+ S EL ++ ++  L  +      IY  ++  N
Sbjct: 129 CAMACLNYNIRAKSLLHCFQCCGAKVLLVSPEL-QAAVEEILPSLKKDDVSIYYVSRTSN 187

Query: 235 KAEYPEGFEIHSMQSVEELGSNPENLGIPPS---RPTPSDMAIVMYTSGSTG 283
                +G +   +  V+E+ + P    IP S     T S  A+ +YTSG+TG
Sbjct: 188 T----DGIDSF-LDKVDEVSTEP----IPESWRSEVTFSTPALYIYTSGTTG 230


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,252,848
Number of Sequences: 37866
Number of extensions: 1272065
Number of successful extensions: 2884
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2793
Number of HSP's gapped (non-prelim): 42
length of query: 711
length of database: 18,247,518
effective HSP length: 109
effective length of query: 602
effective length of database: 14,120,124
effective search space: 8500314648
effective search space used: 8500314648
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.