Guide to the Human Genome
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Search of human proteins with 42476299

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
         (1299 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...  2602   0.0  
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...  2602   0.0  
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...  2583   0.0  
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...  2583   0.0  
gi|92087055 PERQ amino acid rich, with GYF domain 1 [Homo sapiens]    756   0.0  
gi|148746195 trichohyalin [Homo sapiens]                              157   6e-38
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...   140   8e-33
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...   137   5e-32
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...   137   9e-32
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...   135   3e-31
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...   134   4e-31
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...   134   6e-31
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...   134   6e-31
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...   134   7e-31
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...   127   5e-29
gi|102467242 inner centromere protein antigens 135/155kDa isofor...   120   8e-27
gi|102467235 inner centromere protein antigens 135/155kDa isofor...   116   1e-25
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                       114   5e-25
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                       114   5e-25
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                        114   5e-25
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                        114   5e-25
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                        114   5e-25
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                        114   5e-25
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                        114   5e-25
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                        114   5e-25
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]           113   1e-24
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...   108   3e-23
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...   106   2e-22
gi|221139761 zinc finger protein 853 [Homo sapiens]                   105   2e-22
gi|55741709 RNA binding motif protein 25 [Homo sapiens]               104   5e-22

>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
          Length = 1299

 Score = 2602 bits (6745), Expect = 0.0
 Identities = 1299/1299 (100%), Positives = 1299/1299 (100%)

Query: 1    MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
            MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1    MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60

Query: 61   DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
            DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61   DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120

Query: 121  SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
            SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP
Sbjct: 121  SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180

Query: 181  NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGP 240
            NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGP
Sbjct: 181  NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGP 240

Query: 241  RSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF 300
            RSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF
Sbjct: 241  RSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF 300

Query: 301  DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 360
            DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD
Sbjct: 301  DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 360

Query: 361  RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 420
            RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA
Sbjct: 361  RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 420

Query: 421  KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 480
            KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST
Sbjct: 421  KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 480

Query: 481  EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 540
            EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD
Sbjct: 481  EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 540

Query: 541  PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 600
            PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP
Sbjct: 541  PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 600

Query: 601  HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL 660
            HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL
Sbjct: 601  HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL 660

Query: 661  QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG
Sbjct: 661  QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR
Sbjct: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780

Query: 781  EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL
Sbjct: 781  EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840

Query: 841  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
            RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ
Sbjct: 841  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL
Sbjct: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ
Sbjct: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020

Query: 1021 QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD 1080
            QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD
Sbjct: 1021 QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD 1080

Query: 1081 DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE 1140
            DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE
Sbjct: 1081 DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE 1140

Query: 1141 QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA 1200
            QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA
Sbjct: 1141 QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA 1200

Query: 1201 NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS 1260
            NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS
Sbjct: 1201 NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS 1260

Query: 1261 GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1299
            GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY
Sbjct: 1261 GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1299


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
          Length = 1299

 Score = 2602 bits (6745), Expect = 0.0
 Identities = 1299/1299 (100%), Positives = 1299/1299 (100%)

Query: 1    MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
            MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1    MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60

Query: 61   DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
            DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61   DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120

Query: 121  SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
            SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP
Sbjct: 121  SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180

Query: 181  NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGP 240
            NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGP
Sbjct: 181  NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGP 240

Query: 241  RSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF 300
            RSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF
Sbjct: 241  RSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF 300

Query: 301  DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 360
            DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD
Sbjct: 301  DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 360

Query: 361  RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 420
            RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA
Sbjct: 361  RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 420

Query: 421  KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 480
            KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST
Sbjct: 421  KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 480

Query: 481  EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 540
            EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD
Sbjct: 481  EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 540

Query: 541  PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 600
            PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP
Sbjct: 541  PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 600

Query: 601  HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL 660
            HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL
Sbjct: 601  HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL 660

Query: 661  QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG
Sbjct: 661  QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR
Sbjct: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780

Query: 781  EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL
Sbjct: 781  EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840

Query: 841  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
            RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ
Sbjct: 841  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL
Sbjct: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ
Sbjct: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020

Query: 1021 QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD 1080
            QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD
Sbjct: 1021 QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD 1080

Query: 1081 DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE 1140
            DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE
Sbjct: 1081 DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE 1140

Query: 1141 QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA 1200
            QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA
Sbjct: 1141 QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA 1200

Query: 1201 NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS 1260
            NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS
Sbjct: 1201 NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS 1260

Query: 1261 GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1299
            GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY
Sbjct: 1261 GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1299


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
          Length = 1293

 Score = 2583 bits (6696), Expect = 0.0
 Identities = 1293/1299 (99%), Positives = 1293/1299 (99%), Gaps = 6/1299 (0%)

Query: 1    MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
            MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1    MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60

Query: 61   DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
            DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61   DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120

Query: 121  SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
            SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP
Sbjct: 121  SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180

Query: 181  NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGP 240
            NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSP   
Sbjct: 181  NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSP--- 237

Query: 241  RSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF 300
               GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF
Sbjct: 238  ---GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTF 294

Query: 301  DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 360
            DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD
Sbjct: 295  DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 354

Query: 361  RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 420
            RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA
Sbjct: 355  RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 414

Query: 421  KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 480
            KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST
Sbjct: 415  KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 474

Query: 481  EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 540
            EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD
Sbjct: 475  EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 534

Query: 541  PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 600
            PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP
Sbjct: 535  PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 594

Query: 601  HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL 660
            HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL
Sbjct: 595  HMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLL 654

Query: 661  QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG
Sbjct: 655  QQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 714

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR
Sbjct: 715  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774

Query: 781  EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL
Sbjct: 775  EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834

Query: 841  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
            RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ
Sbjct: 835  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 894

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL
Sbjct: 895  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 954

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ
Sbjct: 955  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014

Query: 1021 QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD 1080
            QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD
Sbjct: 1015 QQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWD 1074

Query: 1081 DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE 1140
            DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE
Sbjct: 1075 DAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCE 1134

Query: 1141 QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA 1200
            QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA
Sbjct: 1135 QMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKA 1194

Query: 1201 NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS 1260
            NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS
Sbjct: 1195 NQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQS 1254

Query: 1261 GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1299
            GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY
Sbjct: 1255 GKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1293


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
          Length = 1320

 Score = 2583 bits (6695), Expect = 0.0
 Identities = 1298/1321 (98%), Positives = 1298/1321 (98%), Gaps = 23/1321 (1%)

Query: 1    MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
            MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS
Sbjct: 1    MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60

Query: 61   DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
            DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR
Sbjct: 61   DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120

Query: 121  SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG-- 178
            SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG  
Sbjct: 121  SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK 180

Query: 179  --------------------RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 218
                                RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG
Sbjct: 181  NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 240

Query: 219  GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 278
            GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI
Sbjct: 241  GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 300

Query: 279  DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 338
            DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE
Sbjct: 301  DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 360

Query: 339  GSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKD 398
            GSHNEEAKEPDKTNKKEGEKTDRVGV ASEETPQTSSSSARPGTPSDHQSQEASQFERKD
Sbjct: 361  GSHNEEAKEPDKTNKKEGEKTDRVGV-ASEETPQTSSSSARPGTPSDHQSQEASQFERKD 419

Query: 399  EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 458
            EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP
Sbjct: 420  EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 479

Query: 459  SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 518
            SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE
Sbjct: 480  SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 539

Query: 519  HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 578
            HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ
Sbjct: 540  HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 599

Query: 579  PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 638
            PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ
Sbjct: 600  PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 659

Query: 639  VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 698
            VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA
Sbjct: 660  VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 719

Query: 699  SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 758
            SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ
Sbjct: 720  SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 779

Query: 759  EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
            EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE
Sbjct: 780  EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839

Query: 819  ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
            ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE
Sbjct: 840  ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899

Query: 879  EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
            EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC
Sbjct: 900  EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959

Query: 939  QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998
            QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT
Sbjct: 960  QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019

Query: 999  TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1058
            TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA
Sbjct: 1020 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1079

Query: 1059 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1118
            SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE
Sbjct: 1080 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1139

Query: 1119 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1178
            EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL
Sbjct: 1140 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1199

Query: 1179 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1238
            GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST
Sbjct: 1200 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1259

Query: 1239 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1298
            LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD
Sbjct: 1260 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1319

Query: 1299 Y 1299
            Y
Sbjct: 1320 Y 1320


>gi|92087055 PERQ amino acid rich, with GYF domain 1 [Homo sapiens]
          Length = 1035

 Score =  756 bits (1953), Expect = 0.0
 Identities = 431/840 (51%), Positives = 541/840 (64%), Gaps = 128/840 (15%)

Query: 1   MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 60
           MAAET  LNFGPEWLRALS GGS+ SPP SPA+PKYKLADYRYGREEMLAL++K+NK+P 
Sbjct: 1   MAAET--LNFGPEWLRALSGGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPE 58

Query: 61  DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 120
           +L DKEF  +LQ+EPL PLAL P TEEEQRNFS+SVNS AVLRL G+G G  + G  RGR
Sbjct: 59  ELQDKEFAAVLQDEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLAGTSRGR 118

Query: 121 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGRP 180
            S+R RGRGRG+  FYQRS +E +G FGR   RE+ RSQSW++RG+RRFEK  R+D  R 
Sbjct: 119 GSTRSRGRGRGDSCFYQRSIEEGDGAFGRSP-REIQRSQSWDDRGERRFEKSARRDGARC 177

Query: 181 NFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDGGWRL-AGSRRDGERWRPHSPDG 239
            FEEGG    G + E  RS+SENWR  REEQ  E+E+G WRL AG RRDG+RWR  SPDG
Sbjct: 178 GFEEGG---AGPRKEHARSDSENWRSLREEQE-EEEEGSWRLGAGPRRDGDRWRSASPDG 233

Query: 240 -PRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGS-----------IDDDRDSLPE 287
            PRSAGWREH ERRR+FEFD R      G    R G GS            ++D+D LPE
Sbjct: 234 GPRSAGWREHGERRRKFEFDLRGDRGGCGEEEGRGGGGSSHLRRCRAPEGFEEDKDGLPE 293

Query: 288 WCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKE 347
           WCL+D +EEMGTFD+SGAFL LKK  KEPIPEEQE+DF+ ++E EE S+           
Sbjct: 294 WCLDDEDEEMGTFDASGAFLPLKKGPKEPIPEEQELDFQGLEEEEEPSE----------- 342

Query: 348 PDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEK 407
                          G+E  EE P+       P  P + +S                   
Sbjct: 343 ---------------GLE--EEGPEAGGKELTPLPPQEEKS------------------- 366

Query: 408 AEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVET 467
                    S P+ +P+ G         PL     D        PP   +    +R ++ 
Sbjct: 367 ---------SSPSPLPTLG---------PLWGTNGDGDETAEKEPPAAEDD---IRGIQL 405

Query: 468 PVVGAPGMGSVSTEP---DDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQ----EHR 520
               +PG+GS +  P   +D+EGLKHL+Q+AEK+VA LQDS+L++E+  + +Q     H 
Sbjct: 406 ----SPGVGSSAGPPGDLEDDEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHS 461

Query: 521 AKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPL 580
           A   ++PL H A +KW+YKDPQGEIQGPF  QEMAEWFQAGYF+MSLLVKR CDE FQPL
Sbjct: 462 AAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPL 521

Query: 581 GDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQF--LIQQQYAQ 638
           G+++KMWGRVPF+PGP+PPP +G +DQERL +QQEL A    Q LQ+QQF  L+  +   
Sbjct: 522 GEVIKMWGRVPFAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQQFLQLVSSRQLP 581

Query: 639 VLAQQQKAALS----------SQQQQQLALLLQQFQTLK-MRISDQNIIPSVTRSVSVPD 687
             A ++KAAL            QQQQQL   LQQ Q LK  R  DQN++P+++RS+SVPD
Sbjct: 582 QCALREKAALGDLTPPPPPPPQQQQQQLTAFLQQLQALKPPRGGDQNLLPTMSRSLSVPD 641

Query: 688 TGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMR 747
           +G +W++  +AS  +  E  S+WD+P++++T GP LEQLQ   K       QERRE E+R
Sbjct: 642 SGRLWDVHTSASSQSGGE-ASLWDIPINSSTQGPILEQLQLQHKF------QERREVELR 694

Query: 748 AKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK---QEEALRRQREQEIAL 804
           AKREEEERKR+EE RRQQ      QQEE+++R+EEEEL RRK   Q+E L +  +Q+ A+
Sbjct: 695 AKREEEERKRREEKRRQQ------QQEEQKRRQEEEELFRRKHVRQQELLLKLLQQQQAV 748



 Score =  244 bits (624), Expect = 3e-64
 Identities = 169/442 (38%), Positives = 231/442 (52%), Gaps = 96/442 (21%)

Query: 871  EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 930
            E  +L+H+ +ER+  EL  +R++E  ++R++     +R QQQQ++Q              
Sbjct: 677  EQLQLQHKFQERREVELRAKREEEERKRREE-----KRRQQQQEEQ-------------- 717

Query: 931  QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG-- 988
                                K  +E E   R +  RQQ  L+K LQQQQ           
Sbjct: 718  --------------------KRRQEEEELFRRKHVRQQELLLKLLQQQQAVPVPPAPSSP 757

Query: 989  ---WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSV 1045
               W  ++K   + K+LLE+Q E  RQ+ KQ   ++    P RA+   H           
Sbjct: 758  PPLWAGLAKQGLSMKTLLELQLEGERQLHKQPPPRE----PARAQAPNH--------RVQ 805

Query: 1046 WGSINTGPPNQWASDLVSSIWSNADTK---NSNMGFWDDAVKEVGP--RNSTNKN-KNNA 1099
             G + T P NQW S+    +W   D     +S +G W+D  K  G   R    KN +++ 
Sbjct: 806  LGGLGTAPLNQWVSE-AGPLWGGPDKSGGGSSGLGLWEDTPKSGGSLVRGLGLKNSRSSP 864

Query: 1100 SLSKSVG-VSNRQ-NKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTF 1157
            SLS S   +S R   KK EEEEKLLKL QG+ + QDGFTQWCEQMLH L+   +LDVP  
Sbjct: 865  SLSDSYSHLSGRPIRKKTEEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSATGSLDVPMA 924

Query: 1158 VSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQP 1217
            V+ LKEVESPY+VHDYIR+ LGDT EAKEFAKQFLERRAKQKA+QQRQQQQ         
Sbjct: 925  VAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQ--------- 975

Query: 1218 PQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLL 1277
                          W ++ ++L + FQ N S    +     +  K K++  M+ +DPS+L
Sbjct: 976  ------------EAW-LSSASLQTAFQANHS----TKLGPGEGSKAKRRALMLHSDPSIL 1018

Query: 1278 GFSVNASSERLNMGEIETLDDY 1299
            G+S++ SS     GEIE++DDY
Sbjct: 1019 GYSLHGSS-----GEIESVDDY 1035


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score =  157 bits (397), Expect = 6e-38
 Identities = 97/322 (30%), Positives = 189/322 (58%), Gaps = 39/322 (12%)

Query: 725  QLQQLEKAKAAKLEQERREAEMRAKREEEE---RKRQEELRRQQEEILRRQQEEERKRRE 781
            +L +L +    + +Q+RRE + R  +EEEE   RKR+  LR+++E++   + + +R+ +E
Sbjct: 214  ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273

Query: 782  EEELARRKQEEALRRQREQ----------EIALRRQREEEERQQQEEALRRLEERRREEE 831
            EEE  R+ + + LRR+R++          E  LRR++EEE R+QQEE  RR ++ RRE++
Sbjct: 274  EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE--RREQQERREQQ 331

Query: 832  ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 891
            E R++++L R+QEE   +  R E+E +RR ++ R   EEE    +   E++ R+E +++R
Sbjct: 332  EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391

Query: 892  QKELMRQRQ-QQQEALRRLQQQQQQQQL---AQMKLPSSSTWGQQSNTTACQSQATLSLA 947
            +++L R++Q ++++ LRR QQ +++QQL    Q++        +Q +    + Q      
Sbjct: 392  EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ------ 445

Query: 948  EIQKLEEERERQLREEQRRQQRELMKALQQ-QQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             +++ +EER   L+ E+  ++ E  +  QQ ++ Q++++   W             L+++
Sbjct: 446  RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW-------------LKLE 492

Query: 1007 QEEARQMQKQQQQQQQHQQPNR 1028
            +EE R+ Q++++QQ + +Q  R
Sbjct: 493  EEERREQQERREQQLRREQEER 514



 Score =  151 bits (382), Expect = 3e-36
 Identities = 109/361 (30%), Positives = 202/361 (55%), Gaps = 66/361 (18%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI----LRRQQEEERK- 778
            +QL++ ++ +  + ++ERRE + R  RE++E +R+++LRR+QEE     LRR+QEEER+ 
Sbjct: 304  QQLRRKQEEERREQQEERREQQER--REQQEERREQQLRREQEERREQQLRREQEEERRE 361

Query: 779  ---RREEEELARRKQ---------EEALRRQ----REQEIALRRQREEEERQQQEEALRR 822
               RRE+EE  R +Q         E+ LRR+    REQ++   +Q   E++ ++E+ LRR
Sbjct: 362  QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421

Query: 823  LEERRREEEERR--------KQEELLRKQEEEAAKWAREEEEAQRRLEENR--------- 865
             ++ RRE+EE R        ++E+ L++++EE   W + EEE +R  +E R         
Sbjct: 422  EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481

Query: 866  -------LRMEEEAAR---------LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRL 909
                   L++EEE  R         LR E+EER+ + L+ Q ++E ++QR + ++ LRR 
Sbjct: 482  EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541

Query: 910  QQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ----- 964
            Q+++++Q L + +        ++      Q +    L  +++ EE R+++L+ EQ     
Sbjct: 542  QEERREQLLKREEEKRLEQERREQRLKREQEERRDQL--LKREEERRQQRLKREQEERLE 599

Query: 965  RRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
            +R +RE ++ L+Q+++++Q+         +     KS    +QEE RQ Q +++QQ++ +
Sbjct: 600  QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS---EEQEERRQQQLRREQQERRE 656

Query: 1025 Q 1025
            Q
Sbjct: 657  Q 657



 Score =  149 bits (375), Expect = 2e-35
 Identities = 99/316 (31%), Positives = 187/316 (59%), Gaps = 28/316 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE--EERKRRE 781
            EQL++LE+ +  +  QE  + + R +RE++ R++QEE RR+Q+E  R QQE  E+++ R 
Sbjct: 276  EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335

Query: 782  EEELARRKQE---EALRRQREQEIA---LRRQREEEERQQQ---EEALRRLEERRREEEE 832
            E++L R ++E   + LRR++E+E     LRR++EEE R+QQ   E+ LRR ++ RRE++ 
Sbjct: 336  EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL 395

Query: 833  RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892
            RR+Q +L R+Q+    +  R E++ +R   E +LR E+E  R   ++ E++R+E  ++R+
Sbjct: 396  RREQ-QLRREQQLRREQQLRREQQLRR---EQQLRREQEEER-HEQKHEQERREQRLKRE 450

Query: 893  KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
            +E  R   +++E   R +Q++++QQL            +       +    L   E ++ 
Sbjct: 451  QEERRDWLKREEETERHEQERRKQQLK-----------RDQEEERRERWLKLEEEERREQ 499

Query: 953  EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1012
            +E RE+QLR EQ  ++ + +K  Q+++++ QQ+L     + +     +  L  ++EE R 
Sbjct: 500  QERREQQLRREQEERREQRLKR-QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558

Query: 1013 MQKQQQQQQQHQQPNR 1028
             Q++++Q+ + +Q  R
Sbjct: 559  EQERREQRLKREQEER 574



 Score =  145 bits (365), Expect = 3e-34
 Identities = 248/1159 (21%), Positives = 467/1159 (40%), Gaps = 197/1159 (16%)

Query: 192  RKHEFIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMER 251
            R+ + +R E E  R    EQ  E E    RL   + +   W     +  R    R   + 
Sbjct: 420  RREQQLRREQEEER---HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476

Query: 252  RRRFEFDFRDR-----DDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAF 306
            +R  E + R+R     ++ER  ++ R     +  +++   E  L+  EEE        + 
Sbjct: 477  KRDQEEERRERWLKLEEEERREQQERREQ-QLRREQEERREQRLKRQEEEERLQQRLRSE 535

Query: 307  LSLKKVQKEPIP-----------EEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKE 355
              L++ Q+E              E++  + R   E EE  D      EE ++     ++E
Sbjct: 536  QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595

Query: 356  GEKTDRVGVEASEETPQTSSSSAR--PGTPSDHQSQEA-----------SQFERKDEPKT 402
                 R+  E  E   Q      R     P + + Q+             Q  R+ + + 
Sbjct: 596  ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655

Query: 403  EQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTL 462
            EQ  K EEE   E  L  ++    +E   +  Q L++   + A   +     +P     L
Sbjct: 656  EQRLKREEE---EERLEQRLKREHEEERRE--QELAEEEQEQARERI--KSRIPKWQWQL 708

Query: 463  RPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAK 522
                           V + P  +EG +  ++Q EK      +    +E  A + Q+   +
Sbjct: 709  ESEADA-----RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763

Query: 523  GVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGD 582
                    +A +K      +   + P   Q   +        +    ++  ++ F P   
Sbjct: 764  RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ--------LRAEERQQREQRFLP--- 812

Query: 583  IMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQ 642
                                 E +++   R+Q      ++Q L+ ++ L +++ AQ L +
Sbjct: 813  ---------------------EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851

Query: 643  QQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPT 702
            ++      Q++++     +Q +  K R                      W+L+    +  
Sbjct: 852  EEDGLQEDQERRRSQ---EQRRDQKWR----------------------WQLEEERKRRR 886

Query: 703  VWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQE--RREAEMRAKREEEERKRQEE 760
                         T    PAL++  + E+    + E+E  R E E R ++E+E + R+EE
Sbjct: 887  ------------HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE 934

Query: 761  LRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIA-----LRRQ------RE 809
              +Q+EE L R  EE  KRR +E   + ++++ L+++ EQ +       RRQ      RE
Sbjct: 935  QLQQEEEQLLR--EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992

Query: 810  EEERQQQEEALRR--LEERRREEEER--RKQEELLRKQEEEAAKWAREEEEAQRRLEENR 865
            EEE QQ+EE L R   E+RRR+E ER  RK++EL  +QEEE  +  REE E +R  E  R
Sbjct: 993  EEELQQEEEQLLREEREKRRRQEWERQYRKKDEL--QQEEE--QLLREEREKRRLQERER 1048

Query: 866  LRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 925
               EEE   L+ EEE+   +E E +R++EL RQ ++++E       QQ+++QL + +   
Sbjct: 1049 QYREEE--ELQQEEEQLLGEERETRRRQELERQYRKEEEL------QQEEEQLLREEPEK 1100

Query: 926  SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ----- 980
                 +Q     C+ +  L   E Q L EERE++ R+E  RQ RE  +  Q+++Q     
Sbjct: 1101 RR---RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE 1157

Query: 981  ----QQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSN 1036
                ++Q+    +    +     + LL  +QE+ RQ +++Q ++++  Q  + +      
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE 1217

Query: 1037 LHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNK 1096
               S  +  W         QW  +  +++    D K    G  ++  +++   +     +
Sbjct: 1218 DQRS--DLKW---------QWEPEKENAV---RDNKVYCKGRENEQFRQL-EDSQLRDRQ 1262

Query: 1097 NNASLSKSVGVSNRQNKKVE------------EEEKLLKLFQGVNKAQDGFTQWCEQMLH 1144
            +   L   +G    ++++ E            EEE+L +  Q   K +D  +Q  +Q+L 
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322

Query: 1145 ALNTANNLDVPTFVSFLKE-------VESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAK 1197
                       T   F +E        E P    +  R +  +    +E  ++FLE   +
Sbjct: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQR 1382

Query: 1198 QKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEA 1257
             +  Q+R+++ L ++QQ +  ++  Q  Q +D  +      L     + Q  +++   E 
Sbjct: 1383 LR-RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQL-----SRQERDRKFREEE 1436

Query: 1258 VQSGKKKKKQKMVRADPSL 1276
             Q  ++++++K +  +  L
Sbjct: 1437 QQVRRQERERKFLEEEQQL 1455



 Score =  142 bits (358), Expect = 2e-33
 Identities = 101/323 (31%), Positives = 185/323 (57%), Gaps = 27/323 (8%)

Query: 723  LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK--RR 780
            L + QQL + +  + EQ+ R  +   + +EEER  Q+  + ++E+ L+R+QEE R   +R
Sbjct: 401  LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR 460

Query: 781  EEE----ELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRRLEERRREEEE 832
            EEE    E  RRKQ+  L+R +E+E   RR+R    EEEER++Q+E  RR ++ RRE+EE
Sbjct: 461  EEETERHEQERRKQQ--LKRDQEEE---RRERWLKLEEEERREQQE--RREQQLRREQEE 513

Query: 833  RRKQEELLRKQEEEAAKWAREEEEAQRRLEENR---LRMEEEAARLRHEEEERKRKELEV 889
            RR+Q    +++EE   +  R E++ +R  EE R   L+ EEE    +   E+R ++E E 
Sbjct: 514  RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573

Query: 890  QRQKELMRQRQQQQEALRRLQQQQQQQQLAQM---KLPSSSTWGQQSNTTACQSQATLSL 946
            +R + L R+ +++Q+ L+R Q+++ +Q+L +    +L       Q+      + +    L
Sbjct: 574  RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633

Query: 947  AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             + ++ EE R++QLR EQ+ ++ + +K  ++++++ +Q+L       +     + L E +
Sbjct: 634  LKSEEQEERRQQQLRREQQERREQRLKR-EEEEERLEQRLK---REHEEERREQELAEEE 689

Query: 1007 QEEARQMQKQQQQQQQHQQPNRA 1029
            QE+AR+  K +  + Q Q  + A
Sbjct: 690  QEQARERIKSRIPKWQWQLESEA 712



 Score =  133 bits (334), Expect = 1e-30
 Identities = 101/322 (31%), Positives = 181/322 (56%), Gaps = 36/322 (11%)

Query: 730  EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELA 786
            ++ +  + EQER  AE   + E++ER  Q + +R+ EE+ R++QE    E +R EEE+L 
Sbjct: 135  QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ 194

Query: 787  RRK--------QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER----- 833
              K         EE LRR+   E  LRR+  EE++QQ+ E   R+ +   E+E R     
Sbjct: 195  SCKGHETEEFPDEEQLRRRELLE--LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV 252

Query: 834  -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME-----EEAARLRHEEEERKRKEL 887
             RK+EE L+++E +  +  +EEEE  R+LE   LR E     ++  RLR E++ R+++E 
Sbjct: 253  LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312

Query: 888  EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947
            E + Q+E   +R++QQE  RR QQ+++++Q  Q++        QQ      + +    L 
Sbjct: 313  ERREQQE---ERREQQE--RREQQEERREQ--QLRREQEERREQQLRREQEEERREQQLR 365

Query: 948  EIQKLEEERERQLREEQR-RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
              Q+ EE RE+QLR EQ+ R++++L +   +QQ +++Q+L     + +     +     +
Sbjct: 366  REQE-EERREQQLRREQQLRREQQLRR---EQQLRREQQLRREQQLRREQQLRREQQLRR 421

Query: 1007 QEEARQMQKQQQQQQQHQQPNR 1028
            +++ R+ Q++++ +Q+H+Q  R
Sbjct: 422  EQQLRREQEEERHEQKHEQERR 443



 Score =  130 bits (328), Expect = 6e-30
 Identities = 124/437 (28%), Positives = 222/437 (50%), Gaps = 62/437 (14%)

Query: 605  LDQERLTRQQELTALYQMQHLQYQQ----FLIQQQYAQVLAQQQKAALSSQQ--QQQLAL 658
            L++E+  R+QE    ++ Q L+ Q+    FL ++Q      +Q+K     QQ  +Q+   
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ 1547

Query: 659  LLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTT 718
              +Q +  K R  +Q       + +S  +    + L+    +    E   + D       
Sbjct: 1548 QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE------ 1601

Query: 719  PGPALEQLQQLEKAKAAKLEQERR---EAEMRAKREEEERKRQEELRR--QQEEILRRQQ 773
                 +QL++ E  +  + E++R+   + ++  +REE++  RQE  R+  ++E  LRRQ+
Sbjct: 1602 -----QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE 1656

Query: 774  EEE-------RKRREEEELARRKQEEALRRQ------REQEIALRRQREEEERQQQEEAL 820
             E+       RK REEE+L +  +E+ LRRQ      RE+E  LRRQ  E +  Q+E+ L
Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1716

Query: 821  RRLE-ERRREEEERRKQE---ELLRKQE-------EEAAKWAREEEEAQRR------LEE 863
            RR E ER+  EEE+ +QE   E LR+QE       EE  +  REE++ +R+       EE
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776

Query: 864  NRLRMEEEAARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922
             +LR E E  +LR +E +RK R+E ++++++E  + R QQ++   R +++Q Q +  + +
Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE--LMKALQQQQQ 980
            L       +Q      +++   +  E  + EE+   Q  E++RRQ+RE  L +   ++QQ
Sbjct: 1837 L-------RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889

Query: 981  QQQQKLSGWGNVSKPSG 997
            +++Q+    G +    G
Sbjct: 1890 KEEQRHRQVGEIKSQEG 1906



 Score =  127 bits (319), Expect = 7e-29
 Identities = 97/325 (29%), Positives = 178/325 (54%), Gaps = 40/325 (12%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-----LRRQQEEE 776
            AL Q   L++ K A+ +   +E+ ++ +R+EE+++R E   RQ EE       +++QE+E
Sbjct: 88   ALGQATGLDEEKRARCDG--KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQE 145

Query: 777  RKRREEEELARRKQ--EEALRRQREQEIALRRQ--REEEERQQQEEALRRLEERRREEEE 832
            R+  E EE + +++  E+  R++R++E+  +RQ  +E EER+ +EE L+    +  E EE
Sbjct: 146  RELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSC--KGHETEE 203

Query: 833  RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE-----EERKRKEL 887
               +E+L R++  E  +  REE++ QRR  ++R+  EEE    R  E     EE K +E 
Sbjct: 204  FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEE 263

Query: 888  EVQRQKELMRQRQQ----QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQAT 943
            E QRQ+EL  + +Q    +++ LRR +Q+++QQQ  +++        Q+      Q +  
Sbjct: 264  EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ-QRLRREQQLRRKQEEERREQQEERR 322

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
                  ++ EE RE+QLR EQ  ++ + ++  Q++++++QQ                 L 
Sbjct: 323  EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ-----------------LR 365

Query: 1004 EIQQEEARQMQKQQQQQQQHQQPNR 1028
              Q+EE R+ Q +++QQ + +Q  R
Sbjct: 366  REQEEERREQQLRREQQLRREQQLR 390



 Score =  124 bits (311), Expect = 6e-28
 Identities = 97/370 (26%), Positives = 191/370 (51%), Gaps = 83/370 (22%)

Query: 724  EQLQQLEKAKAAKLEQE---RREAEMRAKREEEERKRQEE------------------LR 762
            +QL + E+ +  +LE++   R+E E +   +E++ +RQE                   L+
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629

Query: 763  RQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE-------------QEIALRRQRE 809
             ++E+ L RQ+ + +   EE +L R+++E+ LR  R+             +E  LRRQ  
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689

Query: 810  EEERQQQEEALRRLEERRR--EEEERRKQEELLRK-QEEEAAKWAREEEEAQRR------ 860
            + + +++E+ LRR E  R+  +EE++ +++EL RK +EEE  +   E+E+ +R+      
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749

Query: 861  LEENRLRMEEEAARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRR----LQQQQQQ 915
            LEE +LR E E  +LR +E +RK R+E ++++++E  + R Q+ +   R    L+Q++++
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809

Query: 916  QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR--------EEQRRQ 967
            QQL   +      W ++        Q  L   E Q+L +ER+RQ R        E+ RR+
Sbjct: 1810 QQLRPQQRDGKYRWEEE--------QLQLEEQE-QRLRQERDRQYRAEEQFATQEKSRRE 1860

Query: 968  QRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPN 1027
            ++EL +  +Q+++Q++++                  ++++E  R+ QK++Q+ +Q  +  
Sbjct: 1861 EQELWQEEEQKRRQERER------------------KLREEHIRRQQKEEQRHRQVGEIK 1902

Query: 1028 RARNNTHSNL 1037
                  H  L
Sbjct: 1903 SQEGKGHGRL 1912



 Score =  123 bits (308), Expect = 1e-27
 Identities = 95/324 (29%), Positives = 177/324 (54%), Gaps = 31/324 (9%)

Query: 723  LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR-QQEEILRRQQEEERKRRE 781
            LE+ QQL + +  K    R E ++  +REE++  RQE  R+  +EE   R+QE +RK RE
Sbjct: 1449 LEEEQQLRQERHRKF---REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505

Query: 782  EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE--ERRREEEERRKQEEL 839
            +E     + +E  R+  E+E  L RQ+ + +  Q+E+ LRR E  ++RR++ +R+ +EE 
Sbjct: 1506 QE----LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561

Query: 840  LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899
              +QE E  + +R+E + + RLEE ++R +E+  +   +E++ +R+E + Q ++E  R+ 
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621

Query: 900  QQQQEALRRLQQQQQQQQLAQMK-LPSSSTWGQQSNTTACQSQATLSLAEIQKL------ 952
            ++ ++ L+  ++QQ  +Q    K L       +Q      +        E ++L      
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681

Query: 953  ----EEERERQLREEQ---RRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 1005
                 +ER+R+ REE+   RRQ+RE  K LQ++QQ ++Q+L       K     +   E 
Sbjct: 1682 QQLRRQERDRKFREEEQQLRRQERE-RKFLQEEQQLRRQELE-----RKFREEEQLRQET 1735

Query: 1006 QQEEARQMQKQQQQQQQHQ-QPNR 1028
            +QE+ R+ ++ ++  ++ Q +P R
Sbjct: 1736 EQEQLRRQERYRKILEEEQLRPER 1759



 Score =  121 bits (304), Expect = 4e-27
 Identities = 124/479 (25%), Positives = 224/479 (46%), Gaps = 64/479 (13%)

Query: 606  DQERLTRQQELTALYQMQHLQY-QQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQ 664
            ++E+L R++      Q    QY ++  +QQ+  Q+L ++Q+     +++Q       Q Q
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208

Query: 665  TLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 724
              K R  D++    +          ++ + +         +   + D  L        L+
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268

Query: 725  QLQQLEKAKAAKLEQERREAEMRAKR--EEEERKRQE---------------ELRRQQEE 767
             L  L + +    EQERR  + R +   EEE+ +R+E               +L R++ E
Sbjct: 1269 HL--LGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREERE 1326

Query: 768  ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER- 826
              RR+QE +RK REEE+L + ++E+ LRRQ        R+  EEE + QE+  + LEE  
Sbjct: 1327 EKRRRQETDRKFREEEQLLQEREEQPLRRQERD-----RKFREEELRHQEQGRKFLEEEQ 1381

Query: 827  --RREEEERR--KQEELLRKQEEEAA------KWAREEEEAQRRLEENRLRMEEEAARLR 876
              RR+E ER+  K+E+ LR QE E        +  REEE+   R E +R +  EE  ++R
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR-KFREEEQQVR 1440

Query: 877  HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ------------QQQQLAQM--- 921
             +E ERK  E E Q ++E  R+ +++++ L+  ++QQ            ++QQL +    
Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500

Query: 922  -KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 980
             K        Q+      + +  L   + Q+   + E+QLR ++R QQR   +  + +++
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560

Query: 981  QQQQKLSGWGNVSKPSGTTKSLLEIQQ-----------EEARQMQKQQQQQQQHQQPNR 1028
            +Q ++      +S+     K  LE Q+           E+ +Q+++Q+ QQQ  Q+ +R
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619



 Score =  120 bits (302), Expect = 6e-27
 Identities = 102/329 (31%), Positives = 171/329 (51%), Gaps = 36/329 (10%)

Query: 724  EQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEE---LRRQQ------EEILRRQ 772
            +QL+  E+ +  + +++R  RE E +  R+E +RK +EE   +RRQ+      EE  + +
Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR 1456

Query: 773  QEEERKRREEEELARRKQEEALRRQR------EQEIALRRQREEEERQQQEEALRRLEER 826
            QE  RK REEE+L + ++E+ L RQ       E+E  LRRQ  E +R+ +E+ LR  E  
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ--ERDRKFREQELRSQEPE 1514

Query: 827  RR--EEEERRKQEELLRKQEEEAAKWAREEEEAQRR-------LEENRLRMEEEAARLRH 877
            R+  EEE++  +++  RK  +E  +  R+E   QRR        EE +LR E E  +L  
Sbjct: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574

Query: 878  EEEERK-RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTT 936
            +E +RK R E +  R++E  R+  + ++ LRR + QQQ +Q    K        Q+    
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634

Query: 937  ACQSQ---ATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVS 993
                Q         E Q   +ERE+QLR ++ R+ RE  + LQ+ ++QQ ++        
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER----D 1690

Query: 994  KPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1022
            +     +  L  Q+ E + +Q++QQ ++Q
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQ 1719



 Score =  116 bits (291), Expect = 1e-25
 Identities = 90/327 (27%), Positives = 184/327 (56%), Gaps = 29/327 (8%)

Query: 724  EQLQQLEKAKAAKLEQE----RREAEMRAKREEEERKRQE--ELRRQQEEILRRQQEEER 777
            EQ  + ++ +   LE+E    R++ + +  +EE++ +RQE  + RRQ  +   R++E+ R
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR 1564

Query: 778  KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE--ERRREEEERRK 835
            + REE++L+R++++   R+ R +E  +RRQ +E +  + E+ LRR E  ++ R+E +R+ 
Sbjct: 1565 QEREEQQLSRQERD---RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621

Query: 836  QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE------EEERKRKELEV 889
            +E+    QE E  +  R+E + +   EE +LR +E   +LRH+      EEE+  +E E 
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681

Query: 890  Q--RQKELMRQRQQQQEALRRLQQQ----QQQQQLAQMKLPSSSTWGQQSNTTACQSQAT 943
            Q  R++E  R+ +++++ LRR +++    Q++QQL + +L       +Q      Q Q  
Sbjct: 1682 QQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR 1741

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
                  + LEEE+ R  REEQ+ +++E  +  ++++Q +Q++        +   + +S  
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQER------EEQQLRSQESDR 1795

Query: 1004 EIQQEEARQMQKQQQQQQQHQQPNRAR 1030
            + ++EE  + ++++QQ +  Q+  + R
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYR 1822



 Score =  115 bits (287), Expect = 4e-25
 Identities = 89/308 (28%), Positives = 170/308 (55%), Gaps = 20/308 (6%)

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEE---RKRQEELRRQQEEILRRQQEEERKRREE 782
            L++  + +  + EQ+ R    R  REEE+      +++LRRQ+ +  + ++EE++ RR+E
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD-RKFREEEQQLRRQE 1704

Query: 783  EELARRKQEEALRRQREQEIALRRQREEEERQQ--QEEALRRLEERRR--EEEERR--KQ 836
             E    ++E+ LRRQ  +    R+ REEE+ +Q  ++E LRR E  R+  EEE+ R  ++
Sbjct: 1705 RERKFLQEEQQLRRQELE----RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760

Query: 837  EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM 896
            E+ LR+QE +  +  REEE+ ++  EE +LR +E   + R EE+ R+ +E +  R ++  
Sbjct: 1761 EQQLRRQERD--RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818

Query: 897  RQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 956
             + + ++E L+  +Q+Q+ +Q    +  +   +  Q  +   + +  L   E QK  +ER
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR--REEQELWQEEEQKRRQER 1876

Query: 957  ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
            ER+LREE  R+Q++  +  +Q  + + Q+  G G + +P   T     +    +   +  
Sbjct: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPG--THQFASVPVRSSPLYEYI 1934

Query: 1017 QQQQQQHQ 1024
            Q+Q+ Q++
Sbjct: 1935 QEQRSQYR 1942



 Score =  113 bits (283), Expect = 1e-24
 Identities = 103/392 (26%), Positives = 180/392 (45%), Gaps = 87/392 (22%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
            E++QQ E+    +  ++RR  E+  +  EEE  +QEE +  +EE  +R+QE ER+ REEE
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203

Query: 784  ELARRKQEEALR---------------------------------------------RQR 798
            EL R+K+++  R                                             RQ 
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263

Query: 799  EQEIA------LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 852
            +Q++         R RE+E R+ Q+      EE + E EE+++ +   RK +EE      
Sbjct: 1264 QQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE 1323

Query: 853  EEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQ---------KELM 896
            E EE +RR        EE +L  E E   LR +E +RK +E E++ Q         ++ +
Sbjct: 1324 EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRL 1383

Query: 897  RQRQQQQEALRRLQQ---QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
            R+++++++ L+  QQ   Q+++QQL Q +        QQ +      +      ++++ E
Sbjct: 1384 RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443

Query: 954  EER-----ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
             ER     E+QLR+E+ R+ RE  + LQ++++QQ  +              +  LE +Q+
Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR----------QERDRKFLEEEQQ 1493

Query: 1009 EARQM--QKQQQQQQQHQQPNRARNNTHSNLH 1038
              RQ   +K ++Q+ + Q+P R        LH
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLH 1525



 Score =  110 bits (275), Expect = 9e-24
 Identities = 89/334 (26%), Positives = 174/334 (52%), Gaps = 45/334 (13%)

Query: 738  EQERR--EAEMRAKREEEERK---RQEELRRQQEEILRRQQEEERKRREEEELAR----- 787
            EQ R+  E E R +R+E ERK    +++LR Q+ E   RQ  + + R EE++L+R     
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430

Query: 788  --RKQEEALRRQR------EQEIALR--------------RQREEEERQQQEEALRRLEE 825
              R++E+ +RRQ       E+E  LR              ++REE++  +QE   + LEE
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490

Query: 826  R---RREEEERRKQEELLRKQEEEAAKWAREEEEAQRR-------LEENRLRMEEEAARL 875
                RR+E +R+ +E+ LR QE E  K+  EE++  R+        EE +LR +E   + 
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPE-RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549

Query: 876  RHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK-LPSSSTWGQQSN 934
            R + + + R+E ++++++E  +  +Q+++   RL++Q+ ++Q  + K +       +Q  
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609

Query: 935  TTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSK 994
                + +      E ++L +ERE Q    Q R ++ L +  Q ++Q+++Q+L       K
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR-HDRDRK 1668

Query: 995  PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1028
                 + L E ++++ R+ ++ ++ +++ QQ  R
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 71/283 (25%), Positives = 119/283 (42%), Gaps = 35/283 (12%)

Query: 153 REMHRSQSWEERGDR--RFEKPGRKD--VGRPNFEEGGPTSVGRKHEFIRSESENWRIFR 208
           +++ +S+  EER  +  R E+  R++  + R   EE     + R+HE  R E E   +  
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE---LAE 687

Query: 209 EEQNGEDE-------DGGWRL---AGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFD 258
           EEQ    E          W+L   A +R+     RP   +G R    +E  E+RRR E +
Sbjct: 688 EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR--QEQEEKRRRRESE 745

Query: 259 FRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIP 318
            + +++ER +R+ +      +  RD   +W  E+  E      S+   L  ++ ++    
Sbjct: 746 LQWQEEERAHRQQQEE----EQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801

Query: 319 EEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSA 378
           E Q+ + R + E EE         E  KE     ++E  +      +  EE         
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE--------- 852

Query: 379 RPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAK 421
             G   D Q +  SQ +R+D+    Q E  EE  R  ++L AK
Sbjct: 853 EDGLQED-QERRRSQEQRRDQKWRWQLE--EERKRRRHTLYAK 892



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 58/287 (20%), Positives = 107/287 (37%), Gaps = 50/287 (17%)

Query: 159 QSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFI------RSESENWRIFREEQ- 211
           Q W+ER +RR E+   +       EE       R+ E +      R E +  R  R+++ 
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237

Query: 212 NGEDEDGGWRLAGS--RRDGERWRPHSPDGPRSAGWREHMERR-RRFEFDFRDRDDERGY 268
             E+E+  WR   +  R++ E+ +   P   R     E   R+  R E     +++E+  
Sbjct: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ 297

Query: 269 RRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPV 328
           +R+R                                    L++ Q+E   E+QE + R  
Sbjct: 298 QRLRREQ--------------------------------QLRRKQEEERREQQE-ERREQ 324

Query: 329 DEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQS 388
            E  E         EE +E     ++E  +  ++  E  EE  +      +     + Q 
Sbjct: 325 QERRE-------QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQL 377

Query: 389 QEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQ 435
           +   Q  R+ + + EQ  + E++ R E  L  +   R ++ +   QQ
Sbjct: 378 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 52/276 (18%), Positives = 109/276 (39%), Gaps = 28/276 (10%)

Query: 138  RSFDEVEGVFGRGGGREMHRSQSWEERGDRRF--EKPGRKDVGRPNFEEGGPTSVGRKHE 195
            R F E E +      +++HR +      DR+F  E+P  +   R            R+ E
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQER-----DRKFLEEEPQLRRQEREQQLRHDRDRKFREEE 1673

Query: 196  FIRSESENWRIFREEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRF 255
             +  E E  ++ R+E++ +  +   +L   R++ ER         R    R+ +ER+ R 
Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLR--RQERERKFLQEEQQLR----RQELERKFRE 1727

Query: 256  EFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKE 315
            E   R   ++   RR       ++++     +   E  E+++   +    F   +++++E
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEE-----QLRPEREEQQLRRQERDRKFREEEQLRQE 1782

Query: 316  PIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSS 375
                 +E   R  +   +  + E    E  ++  +  +++G+          EE  Q   
Sbjct: 1783 ----REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK------YRWEEEQLQLEE 1832

Query: 376  SSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEE 411
               R     D Q +   QF  +++ + E+ E  +EE
Sbjct: 1833 QEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE 1868


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 899

 Score =  140 bits (353), Expect = 8e-33
 Identities = 132/573 (23%), Positives = 269/573 (46%), Gaps = 60/573 (10%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE-----EERK 778
            EQ+Q+ E+ K  + E++ RE E +  R+EE    QE+  R+QE+ +R Q+E     +ER 
Sbjct: 348  EQMQEQEE-KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406

Query: 779  RREEEELARRK----QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE-R 833
            R +EE +  ++    Q E +R +++ +   ++ R++EE+ Q+EE +R  E++ REEEE  
Sbjct: 407  REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466

Query: 834  RKQEELLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892
            R+QEE ++KQEE    W +EE+E  Q+RL E + ++ E+  +++ +EE+   +E +++ Q
Sbjct: 467  REQEEKMQKQEEN--MWEQEEKEWQQQRLPEQKEKLWEQ-EKMQEQEEKIWEQEEKIRDQ 523

Query: 893  KELMRQRQQ--QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ---SNTTACQSQATLSLA 947
            +E+  Q ++  +QE +R  Q+ Q  +Q  +M+      W Q+      T  Q + T    
Sbjct: 524  EEMWGQEKKMWRQEKMRE-QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQE 582

Query: 948  EIQKLEE---ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1002
            E  + EE   ERE+++REE+   R+Q E M+  +++ Q+Q++K+  W    K     + +
Sbjct: 583  EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM--WEQEEKMQEQEEKM 640

Query: 1003 LEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLV 1062
             E  QEE    Q+++  +QQ     + +   H  +                  +   +  
Sbjct: 641  WE--QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ---------------EQEKMQEQE 683

Query: 1063 SSIWS----NADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1118
              IW        T+      WD   +E      + + +      +   +  ++ K  E+E
Sbjct: 684  EKIWEQEKMEKKTQEQEKKTWD---QEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740

Query: 1119 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1178
            EK+ +  + + + ++   +  E+M          +       ++E E  +E  + +R   
Sbjct: 741  EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR--- 797

Query: 1179 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1238
                  +E   +  E + + +  + R Q++    Q+++   Q  +   Q++ +WG     
Sbjct: 798  -----DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852

Query: 1239 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVR 1271
               +    +   +Q      Q  K +++++ +R
Sbjct: 853  EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885



 Score =  132 bits (333), Expect = 2e-30
 Identities = 106/472 (22%), Positives = 231/472 (48%), Gaps = 53/472 (11%)

Query: 607  QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 666
            +E+  R +E   +++      ++  +Q+Q  +   Q++K     + +++   + ++ +T+
Sbjct: 407  REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466

Query: 667  -----KMRISDQNIIPSVTRSVS---VPDTGS-IWELQPTASQPT-VWEGGS-------V 709
                 KM+  ++N+     +      +P+    +WE +    Q   +WE          +
Sbjct: 467  REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526

Query: 710  WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQ 765
            W             EQ  Q+ + +    +QE++    E  M  K +E+E+K  ++  + +
Sbjct: 527  WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMR 586

Query: 766  EEILRRQQEEERKRREEEELARRKQEEALRRQRE--QEIALRRQREEEERQQQEEALRRL 823
            EE   R +E E+K REEEE+ R +QEE ++ Q E  QE   +   +EE+ Q+QEE +   
Sbjct: 587  EE--ERMREREKKMREEEEMMR-EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643

Query: 824  EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM-EEEAARLRHEEEER 882
            EE+  E+EE+  +++ L +Q+E+   W  E+ + Q +++E   ++ E+E    + +E+E+
Sbjct: 644  EEKMWEQEEKMWEQQRLPEQKEKL--WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701

Query: 883  KRKELEVQRQKELMRQRQQ---QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 939
            K  + E  R++E MR+R++   ++E + R Q+++ Q+Q  +M+      W Q+      +
Sbjct: 702  KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761

Query: 940  S---------QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSG-- 988
                      +    L E +K++E+ +   +EE+ R Q E M+  +++ + Q++K+ G  
Sbjct: 762  EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821

Query: 989  ----------WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRAR 1030
                      WG   K  G  + +   +++   +MQ Q+++ ++ ++  R +
Sbjct: 822  EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQ 873



 Score =  127 bits (319), Expect = 7e-29
 Identities = 93/314 (29%), Positives = 174/314 (55%), Gaps = 26/314 (8%)

Query: 738  EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREEEELARRKQEEAL 794
            E+E RE E + +++EE+  RQEE  R+QE  +R Q+E+   + KR  E+E   R+QE+ L
Sbjct: 278  EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337

Query: 795  RRQ---REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEER-RKQEELLRKQEE 845
            R Q   REQE  ++ Q E     EE+ ++QEE + R EER  E+E++ R+QE+ +R QEE
Sbjct: 338  REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397

Query: 846  ---EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ 902
               E  +  RE+EE  R  E+   ++E+     + +E+E+K ++ E + Q+E   +R ++
Sbjct: 398  RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE---ERIRE 454

Query: 903  QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ--SQATLSLAEIQKLEEERERQL 960
            +E   R +++  ++Q  +M+    + W Q+      Q   +    L E +K++E+ E+  
Sbjct: 455  REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514

Query: 961  REEQRRQQRELM----KALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
             +E++ + +E M    K + +Q++ ++Q+   W    K     + + +  QEE  + + Q
Sbjct: 515  EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD--QEERMEKKTQ 572

Query: 1017 QQQQQQHQQPNRAR 1030
            +Q+++   Q  + R
Sbjct: 573  EQEKKTWDQEEKMR 586



 Score =  127 bits (319), Expect = 7e-29
 Identities = 107/455 (23%), Positives = 226/455 (49%), Gaps = 45/455 (9%)

Query: 606  DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            +QE   R+QE     Q + L+ Q+  +++Q  ++  Q++      Q Q+Q   + +Q + 
Sbjct: 304  EQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE- 362

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS-VWDLPLDTTTPGPALE 724
             KMR  ++ +     R           E +    +  +WE    + +            E
Sbjct: 363  -KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 421

Query: 725  QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE-- 782
            Q++++ + K  + EQE++  +   K +EEER R+ E + ++EE   R+QEE+ +++EE  
Sbjct: 422  QVEKMREEKKMQ-EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480

Query: 783  -EELARRKQEEALRRQREQEIALRRQREEEER-QQQEEALR-------------RLEERR 827
             E+  +  Q++ L  Q+E+     + +E+EE+  +QEE +R             R E+ R
Sbjct: 481  WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540

Query: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL------------RMEEEAARL 875
             +E++  +QEE +R QE++   W +EE   ++  E+ +             RM E   ++
Sbjct: 541  EQEDQMWEQEEKMRDQEQK--MWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM 598

Query: 876  RHEEEERKRKELEVQRQKELMRQRQQ---QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 932
            R EEE  + +E ++Q Q+E M+++++   +QE   + Q+++  +Q  +M       W QQ
Sbjct: 599  REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ 658

Query: 933  SNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQ--QQQKLSGWG 990
                    +    L E +K++E+ + Q +EE+  +Q ++ K  Q+Q+++   Q+K+    
Sbjct: 659  R-----LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713

Query: 991  NVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1025
            ++ +     +   E+ +E+  +MQ+Q+++ Q+ ++
Sbjct: 714  SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748



 Score =  120 bits (301), Expect = 8e-27
 Identities = 108/453 (23%), Positives = 216/453 (47%), Gaps = 89/453 (19%)

Query: 604  ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
            E  Q+RL  Q+E   L++ + +Q Q+  I +Q  ++  Q++      +  +Q  +  Q+ 
Sbjct: 487  EWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 544

Query: 664  QTL----KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 719
            Q      KMR  +Q +                W+ +    + T  +    WD        
Sbjct: 545  QMWEQEEKMRDQEQKM----------------WDQEERMEKKTQEQEKKTWD-------- 580

Query: 720  GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQ----QEE 775
                ++ +  E+ +  + E++ RE E   + +EE+ + QEE  ++QEE +  Q    QE+
Sbjct: 581  ----QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ 636

Query: 776  ERKRREEEELARRKQEEALRRQR--EQEIAL---RRQREEEERQQQEEAL---RRLEERR 827
            E K  E+EE    ++E+   +QR  EQ+  L    + +E+E+ Q+QEE +    ++E++ 
Sbjct: 637  EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696

Query: 828  REEE------ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 881
            +E+E      E+ ++EE +R++E    K  REEEE  R  EE   +M+E+  +++ +EEE
Sbjct: 697  QEQEKKTWDQEKMREEESMRERE----KKMREEEEMMREQEE---KMQEQEEKMQEQEEE 749

Query: 882  RKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQ 941
               +E ++  Q+E M ++Q+  E   +L + ++ Q+           W Q+         
Sbjct: 750  MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-------QEKIWEQE--------- 793

Query: 942  ATLSLAEIQKLEEERERQL-REEQRRQQRELMKALQQQQQQQQQKLSG-----WGNVSKP 995
                    +K+ ++ E+   +EE+ R Q E M+  +++   Q++K+ G     WG   K 
Sbjct: 794  --------EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKM 845

Query: 996  SGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1028
             G  + + E  Q +  +M++Q+++ +  ++  R
Sbjct: 846  WGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMR 878



 Score =  117 bits (292), Expect = 9e-26
 Identities = 125/567 (22%), Positives = 261/567 (46%), Gaps = 94/567 (16%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREE--------EERKRQEELRRQQEEILRRQQEE 775
            E  ++L  A++ K E +    E++ K E         +    QEE+ RQ+EE+    +E+
Sbjct: 229  ELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL----REQ 284

Query: 776  ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK 835
            E+K R++EE   R++E    R REQE  +R Q  EE+  +QE+ LR  E+  RE+E+  +
Sbjct: 285  EKKIRKQEEKMWRQEE----RLREQEGKMREQ--EEKMWRQEKRLREQEKELREQEKELR 338

Query: 836  QEELLRKQEE-----EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
            +++ LR+QEE     E   W  E+EE  R  EE   R EE   RL  +E++ + +E +++
Sbjct: 339  EQKELREQEEQMQEQEEKMW--EQEEKMREQEEKMWRQEE---RLWEQEKQMREQEQKMR 393

Query: 891  RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQ---QSNTTACQSQATLSLA 947
             Q+E M    +Q E LR  +++ ++Q+           W Q          Q Q   +  
Sbjct: 394  DQEERM---WEQDERLREKEERMREQE---------KMWEQVEKMREEKKMQEQEKKTRD 441

Query: 948  EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007
            + +K++EE   + RE++ R++ E M+  +Q+++ Q+Q+ + W    K     +  L  Q+
Sbjct: 442  QEEKMQEEERIREREKKMREEEETMR--EQEEKMQKQEENMWEQEEKE--WQQQRLPEQK 497

Query: 1008 EEARQMQKQQQQQQQ-HQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIW 1066
            E+  + +K Q+Q+++  +Q  + R+             +WG        +   +    +W
Sbjct: 498  EKLWEQEKMQEQEEKIWEQEEKIRDQ----------EEMWGQEKKMWRQEKMREQEDQMW 547

Query: 1067 SNAD-TKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLF 1125
               +  ++     WD   +E   + +  + K      + +    R+ +++ E EK ++  
Sbjct: 548  EQEEKMRDQEQKMWDQ--EERMEKKTQEQEKKTWDQEEKM----REEERMREREKKMREE 601

Query: 1126 QGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAK 1185
            + + + Q+   Q  E+ +                  ++ E  +E  + ++       E K
Sbjct: 602  EEMMREQEEKMQEQEEKMQ-----------------EQEEKMWEQEEKMQ-----EQEEK 639

Query: 1186 EFAKQFLERRAKQKANQQRQQQQLPQQQQQ----QPPQQPPQQPQQQDSVWGMNHSTLHS 1241
             + +   E +  ++  +  +QQ+LP+Q+++    +  Q+  +  +Q++ +W        +
Sbjct: 640  MWEQ---EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696

Query: 1242 VFQTNQSNNQQSNFEAVQSGKKKKKQK 1268
              Q  ++ +Q+   E     +++KK +
Sbjct: 697  QEQEKKTWDQEKMREEESMREREKKMR 723



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 100/537 (18%), Positives = 233/537 (43%), Gaps = 45/537 (8%)

Query: 750  REEEERKRQEELRRQQE----EILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR 805
            R ++  +  EEL ++++    E+ R     E  +++  EL   +++  L    + EI L 
Sbjct: 191  RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL---QEKLPLAESEKSEIQLN 247

Query: 806  RQREEEERQQQEEALRRLEERRREEEERRKQEEL------LRKQEEEAAKWAREE--EEA 857
             +  + + ++ +  L +++    +EE  R++EEL      +RKQEE+   W +EE   E 
Sbjct: 248  VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK--MWRQEERLREQ 305

Query: 858  QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 917
            + ++ E   +M  +  RLR +E+E + +E E++ QKEL  Q +Q QE     Q+++  +Q
Sbjct: 306  EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE-----QEEKMWEQ 360

Query: 918  LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQ 977
              +M+      W Q+      + Q      + QK+ ++ ER   +++R +++E     Q+
Sbjct: 361  EEKMREQEEKMWRQEERLWEQEKQMR---EQEQKMRDQEERMWEQDERLREKEERMREQE 417

Query: 978  QQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1037
            +  +Q +K+     + +    T+   E  QEE R  +++++ +++ +             
Sbjct: 418  KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ- 476

Query: 1038 HTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKN 1097
                  ++W         Q   +    +W     +      W+   K         + K 
Sbjct: 477  ----EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK- 531

Query: 1098 NASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTF 1157
               + +   +  ++++  E+EEK+    Q +   ++   +  ++      T +  +    
Sbjct: 532  --KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE--QEKKTWDQEEKMRE 587

Query: 1158 VSFLKEVESPY-EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQ---- 1212
               ++E E    E  + +R       E +E  ++  E+  +Q+   Q Q++++ +Q    
Sbjct: 588  EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647

Query: 1213 -QQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQK 1268
             +Q++   +  + P+Q++ +W   H  +    Q      ++  +E  +  KK ++Q+
Sbjct: 648  WEQEEKMWEQQRLPEQKEKLW--EHEKMQE--QEKMQEQEEKIWEQEKMEKKTQEQE 700



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 138/692 (19%), Positives = 284/692 (41%), Gaps = 110/692 (15%)

Query: 245 WREHMERRRRFEFDFRDRDDE--RGYRRVRSGSGSIDDDRDSL--PEWCLEDAEEEMGTF 300
           WR+  E R + E   R ++++  R   R+R   G + +  + +   E  L + E+E+   
Sbjct: 275 WRQEEELREQ-EKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQ 333

Query: 301 DSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTD 360
           +         + Q+E + E++E  +   ++  E  +      E   E +K  +++ +K  
Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393

Query: 361 RVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPA 420
                  E+               D + +E  +  R+ E   EQ EK  EE +M+     
Sbjct: 394 DQEERMWEQ---------------DERLREKEERMREQEKMWEQVEKMREEKKMQEQ--- 435

Query: 421 KVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVST 480
                 ++   D ++ + +                      +R  E  +           
Sbjct: 436 ------EKKTRDQEEKMQE-------------------EERIREREKKM----------- 459

Query: 481 EPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKD 540
             ++EE ++  E++ +K    + +   + E    +L E + K      M E  +K + ++
Sbjct: 460 -REEEETMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517

Query: 541 PQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPP 600
            +   Q     QE   W Q     M     +  ++  +      KMW +           
Sbjct: 518 EKIRDQEEMWGQEKKMWRQE---KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574

Query: 601 HMGELDQE-------------RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAA 647
                DQE             +  R++E     Q + +Q Q+  +Q+Q  ++  Q++K  
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM- 633

Query: 648 LSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGG 707
              +Q++++    ++    + ++ +Q  +P             +WE +    Q  + E  
Sbjct: 634 --QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK--------LWEHEKMQEQEKMQEQE 683

Query: 708 S-VWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE 766
             +W+            EQ ++    +  + E+  RE E + + EEE  + QEE  ++QE
Sbjct: 684 EKIWE---QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740

Query: 767 EILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR 822
           E ++ Q+EE    E K  E+EE  +  +++ L  Q+E+     + +E+E+  +QEE +R 
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEE--KMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRD 798

Query: 823 LEERRR-EEEERRKQEELLRKQEE-----EAAKWARE------EEEAQRRLEENRLRMEE 870
            EE+ R +EE+ R QEE +R QEE     E   W +E      EE+   + E+   +M+ 
Sbjct: 799 QEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQG 858

Query: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQQ 902
           +  ++R +EE+ + +E +++ Q+E MR ++++
Sbjct: 859 QEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 127/640 (19%), Positives = 241/640 (37%), Gaps = 121/640 (18%)

Query: 208 REEQNGEDEDGGWRLAGSRRDGER--WRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDE 265
           +EEQ  E E+  W      R+ E   WR           W +  + R + E   RD++ E
Sbjct: 346 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEE------RLWEQEKQMREQ-EQKMRDQE-E 397

Query: 266 RGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDF 325
           R + +         D+R       L + EE M   +    +  ++K+++E   +EQE   
Sbjct: 398 RMWEQ---------DER-------LREKEERMR--EQEKMWEQVEKMREEKKMQEQEKKT 439

Query: 326 RPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSD 385
           R  +E  +  +      ++ +E ++T +++ EK  +      E+  +       P     
Sbjct: 440 RDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499

Query: 386 HQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTA 445
              QE  Q   ++E   EQ EK  ++  M      K   R ++M     Q   Q      
Sbjct: 500 LWEQEKMQ--EQEEKIWEQEEKIRDQEEMWGQ--EKKMWRQEKMREQEDQMWEQ------ 549

Query: 446 SPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDS 505
                           +R  E  +             D EE ++   Q+ EK     ++ 
Sbjct: 550 -------------EEKMRDQEQKMW------------DQEERMEKKTQEQEKKTWDQEEK 584

Query: 506 ALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTM 565
             ++ER+  + ++ R +   +    E MQ         E +     QE   W Q     M
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQ---------EQEEKMQEQEEKMWEQEE--KM 633

Query: 566 SLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHL 625
               ++  ++  +      KMW                  +Q+RL  Q+E   L++ + +
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMW------------------EQQRLPEQKE--KLWEHEKM 673

Query: 626 QYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT--------LKMRISDQNIIP 677
           Q Q+ + +Q+  + + +Q+K    +Q+Q++     ++ +          KMR  ++ +  
Sbjct: 674 QEQEKMQEQE--EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMRE 731

Query: 678 SVTRSVSVPDTGSIWELQPTASQPTVWEGGS-VWDLPLDTTTPGPALEQLQQLEKAKAAK 736
              +     +     E +    +  +WE    +W+            E  +  E+ K  +
Sbjct: 732 QEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWE 791

Query: 737 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE-----------EERKRREEEEL 785
            E++ R+ E + + +EE+ + QEE  R QEE +  Q+E           +E K   +EE 
Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851

Query: 786 ARRKQEEALRRQREQEIALRRQRE-----EEERQQQEEAL 820
              K +    + REQE  +R Q E     EE+ + QEE +
Sbjct: 852 MEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 47/246 (19%), Positives = 99/246 (40%), Gaps = 14/246 (5%)

Query: 190 VGRKHEFIRSESENW----RIFREEQNGEDEDGGWRLAGSRRDGER--WRPHSPDGPRSA 243
           +  + E IR + E W    +++R+E+  E ED  W      RD E+  W     D     
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW-----DQEERM 567

Query: 244 GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSS 303
             +   + ++ ++ + + R++ER   R R      +++     E  +++ EE+M   +  
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEER--MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625

Query: 304 GAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVG 363
                 K  ++E    EQE      +E            E+  E +K  ++E  +     
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685

Query: 364 VEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVP 423
           +   E+  + +    +     +   +E S  ER+ + + E+    E+E +M+     K+ 
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQ-EEKMQ 744

Query: 424 SRGDEM 429
            + +EM
Sbjct: 745 EQEEEM 750


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
            protein 6 [Homo sapiens]
          Length = 724

 Score =  137 bits (346), Expect = 5e-32
 Identities = 113/435 (25%), Positives = 222/435 (51%), Gaps = 66/435 (15%)

Query: 609  RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 668
            RL +QQE     Q + +Q  +  IQ+Q  ++  Q++K     ++ ++   ++ + +  KM
Sbjct: 354  RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE-KM 412

Query: 669  RISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGSVWDLPLDTTTPGPALEQL 726
            R  ++                 +WE +      +  +WE                  E++
Sbjct: 413  RRQEE----------------MMWEKEEKMRRQEEMMWEKE----------------EKI 440

Query: 727  QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 786
            ++LE+    K+ ++ +  E   KR+EEE+ R++E R++QE  + RQ  EE+ R +EE++ 
Sbjct: 441  RELEE----KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKI- 493

Query: 787  RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 846
             R+QEE + RQ E+     + REEE+RQ+QEE  R+ EE+ RE+EE  +Q+E + +QEE+
Sbjct: 494  -REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ-EEKIREQEEIWRQKEKIHEQEEK 551

Query: 847  AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 906
                 R++EE   R EE   +M ++  ++R +EE+  R+E +++ Q+E +R   +Q+E +
Sbjct: 552  ----IRKQEEKMWRQEE---KMHDQEEKIREQEEKVWRQEEKIREQEEKIR---EQEEKI 601

Query: 907  RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 966
            R  ++  Q+Q+            G+Q      Q +      E  + +EE+ R+ +E++ R
Sbjct: 602  REQEEMTQEQE---------EKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE-QEKKIR 651

Query: 967  QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1026
            +Q E ++  ++  Q+Q++K+  W    K     + + E +++  RQ +K  +Q+ + +Q 
Sbjct: 652  EQEEKIREQEEMMQEQEEKM--WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709

Query: 1027 NRARNNTHSNLHTSI 1041
                     +L  +I
Sbjct: 710  EEKMQEHQEHLEAAI 724



 Score =  108 bits (271), Expect = 3e-23
 Identities = 85/323 (26%), Positives = 171/323 (52%), Gaps = 47/323 (14%)

Query: 607 QERLTRQQELT-----ALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQ 661
           +E++ RQ+E+       + +++   ++Q  I++Q  +   +++K     ++Q+Q A + +
Sbjct: 423 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWR 481

Query: 662 QFQTLKMRISDQNIIPSVTR----SVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTT 717
           Q +  K+R  ++ I     +       + +   I E +    Q  +W             
Sbjct: 482 QEE--KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR------------ 527

Query: 718 TPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE--- 774
                 ++ +  E+ +  + +++  E E + +++EE+  RQEE    QEE +R Q+E   
Sbjct: 528 ------QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVW 581

Query: 775 --EERKRREEEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRL 823
             EE+ R +EE++  R+QEE +R Q    +EQE  +  Q E     EE+ Q+QEE +RR 
Sbjct: 582 RQEEKIREQEEKI--REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639

Query: 824 EERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 882
           EE+ RE+E++ R+QEE +R+QEE   +   +  E + ++ E   +M+E+  ++R +EE+ 
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699

Query: 883 KRKELEVQRQKELMRQRQQQQEA 905
             +E+ +++Q+E M++ Q+  EA
Sbjct: 700 WEQEVRLRQQEEKMQEHQEHLEA 722



 Score = 98.2 bits (243), Expect = 4e-20
 Identities = 88/345 (25%), Positives = 174/345 (50%), Gaps = 53/345 (15%)

Query: 711  DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 770
            +L  +T T     E+  +L++ K   +E E+ E ++  K  + + +R + L  QQ+    
Sbjct: 269  ELYRNTITDEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---- 323

Query: 771  RQQEEERKRREEEELARRKQEEALRRQREQEIALR-RQREEEERQQQEEALRRLEERRRE 829
             Q E +   +E + ++ + Q +      E E+  R  Q++EE+  +QEE ++  EE+ +E
Sbjct: 324  LQAEADHLGKELQSVSAKLQAQV----EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 379

Query: 830  EEER-RKQEELLRKQEE-----EAAKWAREE------------EEAQRRLEENRLRMEEE 871
            +EE+ R+QEE +R+QEE     E   W +EE            EE  RR EE     EE+
Sbjct: 380  QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439

Query: 872  AARLRHE--EEERKRKELEVQRQKELMR--QRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
               L  +  E+E+ R++ E ++++E +R  +++Q+QEA    Q+++ ++Q  +++     
Sbjct: 440  IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499

Query: 928  TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQ----------RELMKALQQ 977
             W Q+             + E +K+ EE +RQ +EE  RQ+          R+  K  +Q
Sbjct: 500  MWRQEE-----------KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ 548

Query: 978  QQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1022
            +++ ++Q+   W    K     + + E +++  RQ +K ++Q+++
Sbjct: 549  EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK 593



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 58/297 (19%), Positives = 139/297 (46%), Gaps = 23/297 (7%)

Query: 736  KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 795
            +L +ER    +   R     +  +E   + +E L+  + E+ + +   +  +RK E A  
Sbjct: 258  ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 317

Query: 796  RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR-KQEEEAAKWAREE 854
               +Q++        +E Q     L+   E         +Q+E    +QEE+  +W  + 
Sbjct: 318  LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 377

Query: 855  EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ 914
            +E + ++ E   ++ E+  ++R +EE    KE +++RQ+E+M    +++E +RR ++   
Sbjct: 378  QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM---WEKEEKMRRQEEMMW 434

Query: 915  QQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQR-RQQRELMK 973
            +++    +L       ++      + Q    + E +K +E+  +  R+E++ R+Q E ++
Sbjct: 435  EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494

Query: 974  ALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRAR 1030
              +++  +Q++K+                   +QE+ R+ +K+Q+Q++  +Q  + R
Sbjct: 495  EQEEKMWRQEEKIH------------------EQEKIREEEKRQEQEEMWRQEEKIR 533



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 87/500 (17%), Positives = 203/500 (40%), Gaps = 86/500 (17%)

Query: 781  EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 814
            E+E+ A  + +EALRR+ E ++   R                     Q E E R      
Sbjct: 169  EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228

Query: 815  --------QQEEALRRLEERRREE----EERRKQEELLRKQEEEAAKWAREEEEAQRRLE 862
                    + E+AL  +  ++++     EE  K+ + L  +         E +E   +L+
Sbjct: 229  HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 288

Query: 863  ENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922
            E    +E E + ++   +E KRK   ++R K L+ Q+Q Q EA    ++ Q      Q +
Sbjct: 289  EKLQLVESEKSEIQLNVKELKRK---LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 345

Query: 923  LPSSSTW---GQQSNTTACQSQATLSLAE--IQKLEE---ERERQLREEQRRQQRELMKA 974
            +  +  W    QQ      + +  +   E  IQ+ EE   E+E ++RE++ + +R+    
Sbjct: 346  VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 405

Query: 975  LQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ------QEEARQMQKQQQQQQQHQQPNR 1028
             +++++ ++Q+   W    K     + + E +      +E+  + +K ++Q+++ Q+  +
Sbjct: 406  WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 465

Query: 1029 ARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGP 1088
             R         +    +W             + +         +   M   ++ + E   
Sbjct: 466  IREQEKRQEQEA---KMWRQ----------EEKIREQEEKIREQEEKMWRQEEKIHEQEK 512

Query: 1089 RNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNT 1148
                 K +    +        RQ +K+ E+E++ +  + +++ ++   +  E+M      
Sbjct: 513  IREEEKRQEQEEMW-------RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565

Query: 1149 ANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQ 1208
             ++ +        ++ E  +   + IR       E +E  ++  E+  +Q+   Q Q+++
Sbjct: 566  MHDQE----EKIREQEEKVWRQEEKIR-------EQEEKIREQEEKIREQEEMTQEQEEK 614

Query: 1209 LPQQQQQQPPQQPPQQPQQQ 1228
            + +Q+++   Q+   Q Q++
Sbjct: 615  MGEQEEKMCEQEEKMQEQEE 634



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 48/215 (22%), Positives = 97/215 (45%), Gaps = 61/215 (28%)

Query: 606 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
           DQE   R+QE     Q + ++ Q+  I++Q  ++  Q++   ++ +Q++++    ++   
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE---MTQEQEEKMGEQEEKMCE 624

Query: 666 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725
            + ++ +Q                                                  E+
Sbjct: 625 QEEKMQEQE-------------------------------------------------EK 635

Query: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
           +++ E+ K  + E++ RE E + + +EE  + QEE   +QEE   +  E+E K +E+EE 
Sbjct: 636 MRRQEE-KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE---KMCEQEEKMQEQEEK 691

Query: 786 ARRKQEEALRRQREQEIALRRQREE-EERQQQEEA 819
            RR++E    +  EQE+ LR+Q E+ +E Q+  EA
Sbjct: 692 MRRQEE----KMWEQEVRLRQQEEKMQEHQEHLEA 722



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 73/410 (17%), Positives = 162/410 (39%), Gaps = 49/410 (11%)

Query: 869  EEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST 928
            +E+ A  +H+E  R+  E +V   + L  Q+ + Q AL   Q   +Q +     L S   
Sbjct: 170  DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL- 228

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERE-RQLREEQRRQQRELMK------ALQQQQQQ 981
                S   A + +  LS    QK + +R   +L +E+     EL +       L+++  +
Sbjct: 229  --HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 286

Query: 982  QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
             Q+KL    +           L+ + E A+ +  QQQ Q +     +   +  + L   +
Sbjct: 287  LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 346

Query: 1042 G-NSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS 1100
              N +W  +N     +        +W   +        W++ ++E   +    + K    
Sbjct: 347  EENELWNRLNQQQEEK--------MWRQEEKIQE----WEEKIQEQEEKIREQEEKIREQ 394

Query: 1101 LSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSF 1160
              K   +  ++    E+EEK+ +  + + + ++   +  E M                  
Sbjct: 395  EEK---MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK------------ 439

Query: 1161 LKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1220
            ++E+E      + IR       E ++  +Q  E+R +Q+A   RQ++++ +Q++      
Sbjct: 440  IRELEEKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKMWRQEEKIREQEE------ 491

Query: 1221 PPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMV 1270
              +  +Q++ +W      +H   +  +   +Q   E  +  +K ++Q+ +
Sbjct: 492  --KIREQEEKMW-RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 51/276 (18%), Positives = 107/276 (38%), Gaps = 51/276 (18%)

Query: 154 EMHRSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESEN--------WR 205
           +MH  +   E+ ++R E+   ++  +   +E     + R+ E IR + E         WR
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEA---KMWRQEEKIREQEEKIREQEEKMWR 502

Query: 206 I---------FREEQNGEDEDGGWRLAGSRRDGER-WRPHSPDGPRSAGWREHMERRRRF 255
                      REE+  ++++  WR     R+ E  WR       +    R+  E+  R 
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562

Query: 256 EFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKE 315
           E    D+++     ++R     +    + + E      EE++             + Q+E
Sbjct: 563 EEKMHDQEE-----KIREQEEKVWRQEEKIRE-----QEEKI-------------REQEE 599

Query: 316 PIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSS 375
            I E++EM        +E  +  G   E+  E ++  +++ EK  R   +  E+  +   
Sbjct: 600 KIREQEEMT-------QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE 652

Query: 376 SSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEE 411
              +     +   ++  +   ++E   EQ EK +E+
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 688



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 44/212 (20%), Positives = 87/212 (41%), Gaps = 25/212 (11%)

Query: 162 EERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIF-----REEQNGEDE 216
           EE+  R+ EK   ++  R   +      + R+ E IR + E WR       +EE+  + E
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556

Query: 217 DGGWRLAGSRRDGER---------WRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERG 267
           +  WR      D E          WR       +    RE  E+ R  E   ++++++ G
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616

Query: 268 YRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLK-KVQKEPIPEEQEMDFR 326
            +          +++    E  +++ EE+M   +        K + Q+E I E++EM   
Sbjct: 617 EQ----------EEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666

Query: 327 PVDEGEECSDSEGSHNEEAKEPDKTNKKEGEK 358
             ++  E  +      E+ +E ++  +++ EK
Sbjct: 667 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
          Length = 570

 Score =  137 bits (344), Expect = 9e-32
 Identities = 90/318 (28%), Positives = 183/318 (57%), Gaps = 22/318 (6%)

Query: 727  QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE---EE 783
            QQ  +A+A  L +E +    + + + EE +    L +QQEE + RQ+E+ ++R E   E+
Sbjct: 248  QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ 307

Query: 784  ELARRKQEEALRRQREQ--EIALRRQREEEERQQQEEALRRLEERR------REEEERRK 835
            E   R+QEE +RRQ E   E   + +R+EE   ++EE +R LEE+       RE+EE+R+
Sbjct: 308  EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367

Query: 836  QEELLR----KQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEEERKRKELEV 889
            +EE +R    +QE+EA  W +EE+  E + ++ E    M+E+  ++  +EE+   +E E+
Sbjct: 368  EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427

Query: 890  QRQKELMRQRQQQ-QEALRRLQQQQQQ-QQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947
            Q Q+E MR+++++ +E  +++++Q+++ ++  +M        G+Q     C+ +A +   
Sbjct: 428  QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG-KMCEQEAKMQEQ 486

Query: 948  EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007
            E +   +E + + +E++ R+Q E ++  ++  Q+Q++K+  W    K     + + E ++
Sbjct: 487  EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM--WEQEEKMCEQEEKMQEQEE 544

Query: 1008 EEARQMQKQQQQQQQHQQ 1025
            +  RQ +K ++Q+ + +Q
Sbjct: 545  KMRRQEEKMREQEVRLRQ 562



 Score =  125 bits (315), Expect = 2e-28
 Identities = 71/276 (25%), Positives = 162/276 (58%), Gaps = 15/276 (5%)

Query: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE----EERKR 779
           E+    ++ K  + E++ +E E + + +EE+ +RQEE+  ++EE +RRQ+E    +E K 
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346

Query: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 838
           RE EE  +  ++E +R Q E+     + RE+E+RQ+QE  + R EE+ RE+EE+ R+QEE
Sbjct: 347 RELEE--KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404

Query: 839 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
           ++++QEE+  +   +  E +  ++E   +M  +  ++R +E++ + +E +++ Q+E+M++
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 464

Query: 899 RQQQQ--------EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 950
           ++++         E   ++Q+Q+++ +  + K+       ++      + +  +   E +
Sbjct: 465 QEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 524

Query: 951 KLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 986
             E+E +   +EE+ ++Q E M+  +++ ++Q+ +L
Sbjct: 525 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRL 560



 Score =  121 bits (304), Expect = 4e-27
 Identities = 83/271 (30%), Positives = 161/271 (59%), Gaps = 47/271 (17%)

Query: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
           E++   ++ K  +LE++  E E   K  E+E KRQEE + +++E  +RQ++E +  R+EE
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQE---KIREQEEKRQEEEKIREQE--KRQEQEAKMWRQEE 390

Query: 784 ELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEER- 833
           ++  R+QEE +R Q    +EQE  +  Q E     EEE Q+QEE +RR EE+ RE+E++ 
Sbjct: 391 KI--REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448

Query: 834 RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK 893
           R+QEE +R+QEE         +E + ++ E   +M E+ A+++ +EE+ +R+E +++ Q+
Sbjct: 449 REQEEKIREQEEMM-------QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501

Query: 894 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
           + +R   +Q+E +R  ++  Q+Q+           W Q+     C+ +        +K++
Sbjct: 502 KKIR---EQEEKIREQEEMMQEQE--------EKMWEQEEK--MCEQE--------EKMQ 540

Query: 954 EERERQLREEQRRQQRELMKALQQQQQQQQQ 984
           E+ E+  R+E++ +++E+   L+QQ+++ Q+
Sbjct: 541 EQEEKMRRQEEKMREQEV--RLRQQEEKMQE 569



 Score =  112 bits (279), Expect = 3e-24
 Identities = 90/326 (27%), Positives = 172/326 (52%), Gaps = 20/326 (6%)

Query: 610 LTRQQELTALYQMQHLQYQ-QFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 668
           L  QQ+L A  +  HL  + Q +  +  AQV   +    L+ QQ++++    ++ Q  + 
Sbjct: 245 LLPQQQLQA--EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREE 302

Query: 669 RISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGS-VWDLPLDTTTPGPALEQ 725
           +I +Q                 +WE +      +  +WE    + +L           EQ
Sbjct: 303 KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 362

Query: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREE 782
            ++ ++ +  + +++R+E E +  R+EE+ + QEE  R+QEE+++ Q+E   E+ ++  E
Sbjct: 363 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWE 422

Query: 783 EELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEER 833
           +E   ++QEE +RRQ    REQE  +R Q E     EE  Q+QEE +   E +  E+E +
Sbjct: 423 QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482

Query: 834 -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892
            ++QEE +R+QEE+  +  ++  E + ++ E    M+E+  ++  +EE+   +E ++Q Q
Sbjct: 483 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 542

Query: 893 KELM-RQRQQQQEALRRLQQQQQQQQ 917
           +E M RQ ++ +E   RL+QQ+++ Q
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKMQ 568



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 80/325 (24%), Positives = 162/325 (49%), Gaps = 37/325 (11%)

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERKRREE 782
            +++L K + A   +  R      + +E+  K QE+L+    ++ EI    +E +RK    
Sbjct: 183  IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 242

Query: 783  EELARRKQEEALRRQREQEIA-----LRRQREEEE-----RQQQEEALRRLEERRREEEE 832
            + L  ++Q +A      +E+      L+ Q EE E      QQQEE + R EE+ +E EE
Sbjct: 243  KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREE 302

Query: 833  RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE--EEERKRKELE-- 888
            +      +++QEE+     RE+EE  RR EE     EE+  R      E+E K +ELE  
Sbjct: 303  K------IQEQEEKI----REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352

Query: 889  VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQM-----KLPSSSTWGQQSNTTACQSQAT 943
            +  Q+++  Q +++QE  +  +Q+++Q+Q A+M     K+       ++      + +  
Sbjct: 353  MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
            +   E +  E+E E Q +EE+ R+Q E ++  +++ ++Q++K+     + +         
Sbjct: 413  MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE----- 467

Query: 1004 EIQQEEARQMQKQQQQQQQHQQPNR 1028
            ++ ++E +  +++ + Q+Q ++  R
Sbjct: 468  KMGEQEGKMCEQEAKMQEQEEKMRR 492



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 64/324 (19%), Positives = 136/324 (41%), Gaps = 90/324 (27%)

Query: 781  EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 814
            E+E+ A  + +EALRR+ E ++   R                     Q E E R      
Sbjct: 96   EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155

Query: 815  -------------------QQEEALRRLEERRRE------------------EEERRKQE 837
                               Q+++A R +EE  +E                  +E+  K +
Sbjct: 156  HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 215

Query: 838  ELLRKQEEEAAKWAREEEEAQRRLEENRL-----RMEEEAARLRHE------------EE 880
            E L+  E E ++     +E +R+LE  +L     +++ EA  L  E            EE
Sbjct: 216  EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 275

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMKLPSSSTWGQQSNTTAC 938
                  L  Q+++++ RQ ++ QE   ++Q+Q++  ++Q  +M+      W ++      
Sbjct: 276  NELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335

Query: 939  QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998
            +        +I++LEE+   Q +  ++ ++R+  + +++Q+++Q+Q+   W    K    
Sbjct: 336  EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK---- 391

Query: 999  TKSLLEIQQEEARQMQKQQQQQQQ 1022
                +  Q+E+ R+ ++  Q+Q++
Sbjct: 392  ----IREQEEKIREQEEMMQEQEE 411



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 74/411 (18%), Positives = 157/411 (38%), Gaps = 66/411 (16%)

Query: 869  EEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST 928
            +E+ A  +H+E  R+  E +VQ  + L  Q+ + Q AL   Q   +Q +     L S   
Sbjct: 97   DEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL- 155

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERE-RQLREEQRRQQRELMK------ALQQQQQQ 981
                S   A + +  LS    QK + +R   +L +E+     EL +       L+++  +
Sbjct: 156  --HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 213

Query: 982  QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
             Q+KL    +           L+ + E A+ +  QQQ Q +     +   +  + L   +
Sbjct: 214  LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273

Query: 1042 -GNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS 1100
              N +W                                           N  N+ +    
Sbjct: 274  EENELW-------------------------------------------NRLNQQQEEKM 290

Query: 1101 LSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSF 1160
              +   +  R+ K  E+EEK+ +  + + + ++   +  E+M          +       
Sbjct: 291  WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-----EK 345

Query: 1161 LKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1220
            ++E+E      + IR       E ++  +Q  E+R +Q+A   RQ++++ +Q+++   Q+
Sbjct: 346  IRELEEKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKMWRQEEKIREQEEKIREQE 403

Query: 1221 PPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVR 1271
              +  Q+Q+   G        +++  +   +Q      Q  K ++++K +R
Sbjct: 404  --EMMQEQEEKMGEQE---EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
            sapiens]
          Length = 750

 Score =  135 bits (340), Expect = 3e-31
 Identities = 118/463 (25%), Positives = 233/463 (50%), Gaps = 59/463 (12%)

Query: 609  RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 668
            RL +QQE     Q + +Q  +  IQ+Q  ++  Q++K     ++ ++   ++ + +  KM
Sbjct: 293  RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE-KM 351

Query: 669  RISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGS-VWDLPLDTTTPGPALEQ 725
            R  ++ +     +     +   +WE +      +  +WE    + +L           EQ
Sbjct: 352  RRQEEMMWEKEEKMRRQEEM--MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---------EE 776
             ++ ++ +  + +++R+E E +  R+EE+ + QEE  R+QE+ + RQ+E         EE
Sbjct: 410  EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469

Query: 777  RKRREEEELARRK------------------QEEALRRQRE----QEIALRRQRE----- 809
             KR+E+EE+ R++                  QEE +R+Q E    QE  +R Q E     
Sbjct: 470  EKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529

Query: 810  EEERQQQEEALRRLEERRREEEERRKQEELL---RKQEEEAAKWAREEEEAQRRLEENRL 866
            EE+  +QEE +R  EE  REEE+  +QE++    ++QE+E   W   +EE  R  EE   
Sbjct: 530  EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW--RQEEKIREQEEKVW 587

Query: 867  RMEEEAARLRHEEEERKRKELEVQRQKELMRQR----QQQQEALRRLQQQQQQQQLAQMK 922
            R EE   ++R +EE+R+ +E ++ +Q+E +R++    Q+Q+E +R  +++ ++Q+  +M 
Sbjct: 588  RQEE---KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE--EMT 642

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
                   G+Q      Q +      E    +EE+ R+ +E++ R+Q E ++  ++  Q+Q
Sbjct: 643  QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE-QEKKIREQEEKIREQEEMMQEQ 701

Query: 983  QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1025
            ++K+  W    K     + + E +++  RQ +K  +Q+ + +Q
Sbjct: 702  EEKM--WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742



 Score =  122 bits (307), Expect = 2e-27
 Identities = 103/408 (25%), Positives = 207/408 (50%), Gaps = 64/408 (15%)

Query: 607 QERLTRQQELT-----ALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQ 661
           +E++ RQ+E+       + +++   ++Q  I++Q  +   +++K     ++Q+Q A + +
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWR 434

Query: 662 QFQTLKMRISDQNIIPSVTR----SVSVPDTGSIWELQPTASQPTVW-------EGGSVW 710
           Q +  K+R  ++ I     +       + +   I E +    Q  +W       E   +W
Sbjct: 435 QEE--KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492

Query: 711 DLPLDTTTPGPALEQLQQLEKA--KAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI 768
                        EQ +++ K   K  + E++ RE E + + +EE+  RQEE  R+QEE+
Sbjct: 493 ------RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546

Query: 769 LRRQQEEERKRREEEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEA 819
            R +++   + +  EE  R++QE+ + RQ    REQE  + RQ E     EE+RQ+QEE 
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606

Query: 820 LRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
           + + EE+ RE+EE+ ++QEE +R+QEE+  +     +E + ++ E   +M E+  +++ +
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666

Query: 879 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
           EE   R+E +++ Q++ +R+   Q+E +R  ++  Q+Q+           W Q+      
Sbjct: 667 EETMWRQEEKIREQEKKIRE---QEEKIREQEEMMQEQE--------EKMWEQEE----- 710

Query: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 986
                      +  E+E + Q +EE+ R+Q E M   + + +QQ++K+
Sbjct: 711 -----------KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747



 Score =  109 bits (272), Expect = 2e-23
 Identities = 82/307 (26%), Positives = 165/307 (53%), Gaps = 45/307 (14%)

Query: 606 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
           +QE + RQ+E   +++ + +  Q+  + +Q  ++  Q++K     ++ ++        Q 
Sbjct: 474 EQEEMWRQEE--KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE--------QE 523

Query: 666 LKMRISDQNIIPSVTRSVSVPDTGSIW-ELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 724
            K+R  ++ +     +   + +   +W E +    Q  +WE                  E
Sbjct: 524 EKIREQEEKMW---RQEEKIREQEEMWREEEKMHEQEKIWE------------------E 562

Query: 725 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE--- 781
           + +Q ++ K  + E++ RE E +  R+EE+ + QEE R++QEE + +Q+E+ R++ E   
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622

Query: 782 EEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREEEE 832
           E+E   R+QEE +R Q    +EQE  +  Q E     EE+ Q+QEE + R EE+ RE+E+
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682

Query: 833 R-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 891
           + R+QEE +R+QEE   +   +  E + ++ E   +M+E+  ++R +EE+   +E+ +++
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742

Query: 892 QKELMRQ 898
           Q+E M++
Sbjct: 743 QEEKMQE 749



 Score =  105 bits (262), Expect = 3e-22
 Identities = 67/209 (32%), Positives = 126/209 (60%), Gaps = 14/209 (6%)

Query: 723 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKR 779
           + + +++ + +    EQE+   E + + +E++  RQEE  R+QEE + RQ+E   E+ ++
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599

Query: 780 REEEELARRKQEEALRRQ----REQEIALRRQRE-----EEERQQQEEALRRLEERRREE 830
           R+E+E    KQEE +R Q    +EQE  +R Q E     EE  Q+QEE +   EE+  E+
Sbjct: 600 RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 659

Query: 831 EER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEV 889
           EE+ ++QEE + +QEE+  +  ++  E + ++ E    M+E+  ++  +EE+   +E ++
Sbjct: 660 EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719

Query: 890 QRQKELMRQRQQQQ-EALRRLQQQQQQQQ 917
           Q Q+E MR+++++  E   RL+QQ+++ Q
Sbjct: 720 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748



 Score =  101 bits (251), Expect = 5e-21
 Identities = 116/561 (20%), Positives = 249/561 (44%), Gaps = 73/561 (13%)

Query: 711  DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 770
            +L  +T T     E+  +L++ K   +E E+ E ++  K  + + +R + L  QQ+    
Sbjct: 208  ELYRNTITDEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---- 262

Query: 771  RQQEEERKRREEEELARRKQEEALRRQREQEIALR-RQREEEERQQQEEALRRLEERRRE 829
             Q E +   +E + ++ + Q +      E E+  R  Q++EE+  +QEE ++  EE+ +E
Sbjct: 263  LQAEADHLGKELQSVSAKLQAQV----EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318

Query: 830  EEER-RKQEELLRKQEE-----EAAKWAREE------------EEAQRRLEENRLRMEEE 871
            +EE+ R+QEE +R+QEE     E   W +EE            EE  RR EE     EE+
Sbjct: 319  QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378

Query: 872  AARLRHE--EEERKRKELE--VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
              R      E+E K +ELE  +  Q+++  Q +++QE  +  +Q+++Q+Q A+M      
Sbjct: 379  MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 438

Query: 928  TWGQQSNTTACQS---QATLSLAEIQKLEEERERQLREEQRRQQ----------RELMKA 974
               Q+      +    +    + E +K+ EE +RQ +EE  RQ+          R+  K 
Sbjct: 439  IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM 498

Query: 975  LQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTH 1034
             +Q+++ ++Q+   W    K     + + E +++  RQ +K ++Q++  ++  +      
Sbjct: 499  HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQ-- 556

Query: 1035 SNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNAD-TKNSNMGFW--DDAVKEVGPRNS 1091
                      +W         +   +    +W   +  +      W  ++ ++E   +  
Sbjct: 557  --------EKIW-------EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601

Query: 1092 TNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANN 1151
              + K    + K       Q +K++E+E+ ++  +   + Q+  TQ  E+    +     
Sbjct: 602  EQEEK----MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE---KMGEQEE 654

Query: 1152 LDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQ 1211
                      ++ E+ +   + IR       E +E  ++  E   +Q+     Q++++ +
Sbjct: 655  KMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714

Query: 1212 QQQQQPPQQPPQQPQQQDSVW 1232
            Q+++   Q+   + +Q++ +W
Sbjct: 715  QEEKMQEQEEKMR-RQEEKMW 734



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 95/546 (17%), Positives = 227/546 (41%), Gaps = 49/546 (8%)

Query: 736  KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 795
            +L +ER    +   R     +  +E   + +E L+  + E+ + +   +  +RK E A  
Sbjct: 197  ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 256

Query: 796  RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR-KQEEEAAKWAREE 854
               +Q++        +E Q     L+   E         +Q+E    +QEE+  +W  + 
Sbjct: 257  LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 316

Query: 855  EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ 914
            +E + ++ E   ++ E+  ++R +EE    KE +++RQ+E+M +++++     R Q++  
Sbjct: 317  QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM----RRQEEMM 372

Query: 915  QQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER--ERQLREEQRRQQRELM 972
             ++  +M+      W ++      + +      +I++ EE+R  E ++RE+++RQ++E  
Sbjct: 373  WEKEEKMRRQEEMMWEKEEKIRELEEKMH-EQEKIREQEEKRQEEEKIREQEKRQEQEAK 431

Query: 973  ------KALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1026
                  K  +Q+++ ++Q+   W    K     K   E +++E  +M +Q+++  + ++ 
Sbjct: 432  MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491

Query: 1027 NRARNNTHSNLH--TSIGNSVW-GSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAV 1083
             R +   H            VW          +   +    +W   +        W +  
Sbjct: 492  WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551

Query: 1084 KEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQML 1143
            K         + K      K      RQ +K+ E+E+  K+++   K ++   +  EQ  
Sbjct: 552  KMHEQEKIWEEEKRQEQEDKMW----RQEEKIREQEE--KVWRQEEKIREQEEKRQEQ-- 603

Query: 1144 HALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQ 1203
                                 E  ++  + IR       E +E  ++  E+  +Q+   Q
Sbjct: 604  --------------------EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643

Query: 1204 RQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKK 1263
             Q++++ +Q+++   Q+   Q +Q++++W           Q  +   Q+      +   +
Sbjct: 644  EQEEKMGEQEEKMCEQEEKMQ-EQEETMWRQEEKIRE---QEKKIREQEEKIREQEEMMQ 699

Query: 1264 KKKQKM 1269
            ++++KM
Sbjct: 700  EQEEKM 705



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 97/548 (17%), Positives = 214/548 (39%), Gaps = 97/548 (17%)

Query: 781  EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 814
            E+E+ A  + +EALRR+ E ++   R                     Q E E R      
Sbjct: 108  EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167

Query: 815  --------QQEEALRRLEERRREE----EERRKQEELLRKQEEEAAKWAREEEEAQRRLE 862
                    + E+AL  +  ++++     EE  K+ + L  +         E +E   +L+
Sbjct: 168  HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227

Query: 863  ENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922
            E    +E E + ++   +E KRK   ++R K L+ Q+Q Q EA    ++ Q      Q +
Sbjct: 228  EKLQLVESEKSEIQLNVKELKRK---LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERER-QLREEQRRQQRELMKALQQQQQQ 981
            +  +  W + +     Q Q      + +K++E  E+ Q +EE+ R+Q E  K  +Q+++ 
Sbjct: 285  VEENELWNRLN-----QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE--KIREQEEKM 337

Query: 982  QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
            ++Q+   W    K     +   E+  E+  +M++Q++   + ++  R +           
Sbjct: 338  RRQEEMMWEKEEK----MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE---------- 383

Query: 1042 GNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASL 1101
               +W         +   +L   +      +       +   +E   R    + +  A +
Sbjct: 384  -EMMW------EKEEKIRELEEKMHEQEKIREQE----EKRQEEEKIREQEKRQEQEAKM 432

Query: 1102 SKSVGVSNRQNKKVEEEEKLL-----KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPT 1156
             +       Q +K+ E+EK +     K+ +     ++   Q  E+M       +  +   
Sbjct: 433  WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE--- 489

Query: 1157 FVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ--- 1213
                 ++ E  +E  + IR         +E  ++  E+  +Q+    RQ++++ +Q+   
Sbjct: 490  --EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547

Query: 1214 -------QQQPPQQPPQQPQQQDSVWGMNHSTL---HSVFQTNQSNNQQSNFEAVQSGKK 1263
                   +Q+   +  ++ +Q+D +W            V++  +   +Q      Q  K 
Sbjct: 548  REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607

Query: 1264 KKKQKMVR 1271
             K+++ +R
Sbjct: 608  WKQEEKIR 615



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 59/282 (20%), Positives = 112/282 (39%), Gaps = 42/282 (14%)

Query: 153 REMHRSQSWEERGDRRFEKPGRKDVGRPNFEEG---GPTSVGRKHEFIRSESENWR---- 205
           R+  +    EE+  ++ EK  R++      EE        + R+ E IR + E WR    
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552

Query: 206 ------IFREEQNGEDEDGGWRLAGSRRDGER--WRPHSPDGPRSAGWREHMERRRRFEF 257
                 I+ EE+  E ED  WR     R+ E   WR       +    RE  E+R+  E 
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR-------QEEKIREQEEKRQEQEE 605

Query: 258 DFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPI 317
               +++     ++R     I +  + + E   +  E+E            + + Q+E +
Sbjct: 606 KMWKQEE-----KIREQEEKIQEQEEKIREQEEKIREQE-----------EMTQEQEEKM 649

Query: 318 PEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSS 377
            E++E      ++ +E  ++     E+ +E +K  +++ EK  R   E  +E  +     
Sbjct: 650 GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI-REQEEMMQEQEEKMWEQ 708

Query: 378 ARPGTPSDHQSQEASQFERKDEPKTEQTE---KAEEETRMEN 416
                  + + QE  +  R+ E K  + E   + +EE   E+
Sbjct: 709 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 828

 Score =  134 bits (338), Expect = 4e-31
 Identities = 133/575 (23%), Positives = 263/575 (45%), Gaps = 73/575 (12%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE----EERKR 779
            E  ++LE+AK    + +    +    R+EEE + QE+  R+QEE + RQ+E    +E K 
Sbjct: 212  ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 271

Query: 780  REEEELARRKQEEALRRQ----REQEIALRRQR----EEEERQQQEEALRRLEERRREEE 831
            RE+EE  RR QE+ LR Q    REQE  LR Q+    +EE+ Q+QEE +   EE+ RE+E
Sbjct: 272  REQEEKMRR-QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330

Query: 832  ERR-KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
            E+  +QEE L +QE++     RE+E+  R  EE   RM E+  RLR E+EER R++ ++ 
Sbjct: 331  EKMWRQEERLWEQEKQM----REQEQKMRDQEE---RMWEQDERLR-EKEERMREQEKMW 382

Query: 891  RQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMKLPSSSTWGQQSNTTACQS--QATLSL 946
             Q+E M++ ++ +E  ++++++++  ++Q  +M+    + W Q+      Q   +    L
Sbjct: 383  EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442

Query: 947  AEIQKLEEERERQLREEQRRQQRELM----KALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1002
             E +K++E+ E+   +E++ + +E M    K + +Q++ ++Q+   W             
Sbjct: 443  WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW------------- 489

Query: 1003 LEIQQEEARQMQKQQ---QQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWAS 1059
               +QEE  + Q+Q+   Q+++  +Q  R R                          W  
Sbjct: 490  ---EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK--------------KMWQQ 532

Query: 1060 DLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEE 1119
            +    +     T+      WD   K    R      +    + +   +   Q +K++E+E
Sbjct: 533  E--EKMREEKKTQEQEKKTWDQEEKM---REEERMREREKKMREEEEMMREQEEKMQEQE 587

Query: 1120 KLL-----KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYI 1174
            + +     K+++   K Q+   +  EQ            +      + E E   +  +  
Sbjct: 588  EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647

Query: 1175 RAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGM 1234
                 +    +E   +  E + + +  + R+Q++  Q Q+++  +Q  +   Q++ +WG 
Sbjct: 648  MWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ 707

Query: 1235 NHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1269
                     +       +   E ++  K+K ++++
Sbjct: 708  EEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL 742



 Score =  127 bits (320), Expect = 5e-29
 Identities = 118/493 (23%), Positives = 234/493 (47%), Gaps = 84/493 (17%)

Query: 606  DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            +QE   R+QE     Q + L+ Q+  +++Q  ++  Q++      Q Q+Q   + +Q + 
Sbjct: 266  EQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE- 324

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA---SQPTVWEGGSVWDLPLDTTTPGPA 722
             KMR  ++ +     R         +WE +       Q    +   +W+           
Sbjct: 325  -KMREQEEKMWRQEER---------LWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374

Query: 723  LEQLQQLEKAKAAKLEQER-REAEMRAKREEEERKRQEELRRQQEEILRRQQEEE----- 776
            + + +++ + +    E+ER RE E + + EEE  + QEE  ++QEE +  Q+E+E     
Sbjct: 375  MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434

Query: 777  ----------RKRREEEELARRKQEEALRRQRE---QEIALRRQ---REEEERQ------ 814
                      +++ +E+E    +QEE +R Q E   QE  + RQ   RE+E++       
Sbjct: 435  LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494

Query: 815  ----------------QQEEALRRLEERRREEEERRKQEELLRK----QEEEAAKWAREE 854
                            +Q+E LR  EER RE+++  +QEE +R+    QE+E   W +EE
Sbjct: 495  MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554

Query: 855  E-EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM-RQRQQQQEALRRLQQQ 912
            +   + R+ E   +M EE   +R +EE+ + +E +++ Q+E M  Q ++ QE   ++ +Q
Sbjct: 555  KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 614

Query: 913  Q----QQQQLAQMKLPSSSTWG-----QQSNTTACQSQATLSLAEIQKLEEERERQLREE 963
            +    +Q++  +M+      W      Q+      + +  +   E +  E+E + Q +EE
Sbjct: 615  EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674

Query: 964  QRRQQRELMKALQQQQQQQQQKLSG-----WGNVSKPSGTTKSLL---EIQQEEAR---Q 1012
            + R+Q E M+  +++ ++Q++K+ G     WG   K  G  + +    E++++E R   Q
Sbjct: 675  KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734

Query: 1013 MQKQQQQQQQHQQ 1025
             +K Q++  +H++
Sbjct: 735  KEKMQERLPEHEE 747



 Score =  125 bits (313), Expect = 3e-28
 Identities = 113/469 (24%), Positives = 223/469 (47%), Gaps = 79/469 (16%)

Query: 606  DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            +QE+  R+QE     Q + L+ Q+  +++Q  ++  Q+++  L  Q+++      +  + 
Sbjct: 245  EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKR--LREQEKELREQEKELREQ 302

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725
             K+R  ++ +     +     +     E +    +  +WE                  ++
Sbjct: 303  KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE------------------QE 344

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQ---EEERKRREE 782
             Q  E+ +  + ++ER   +    RE+EER R++E   +QEE ++ ++   E E+K REE
Sbjct: 345  KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404

Query: 783  EELAR------RKQEEALRRQREQEIALRRQREEEER-------QQQEEALRRLEERRRE 829
            EE  R      +KQEE +  Q E+E   +R  E++E+       Q+QEE +   EE+ R+
Sbjct: 405  EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 464

Query: 830  EEE-------------RRKQEELLRKQEE-----EAAKWAREEE--EAQRRLEENRLRME 869
            +EE              R+QE+ + +QEE     E   W +EE   E   RL E   RM 
Sbjct: 465  QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMR 524

Query: 870  EEAARLRHEEEERKRKELEVQ-----------RQKELMRQRQ---QQQEALRRLQQQQQQ 915
            E+    + EE+ R+ K+ + Q           R++E MR+R+   +++E + R Q+++ Q
Sbjct: 525  EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 584

Query: 916  QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 975
            +Q  +M+      W Q+      Q Q      + +K+ E+ E    E++ ++Q E+M   
Sbjct: 585  EQEEKMREQEEKMWEQEEK---MQEQEEKMWEQEEKMWEQEE----EDKMQEQEEMMWEQ 637

Query: 976  QQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
            +++ Q+Q++K+  W    K     + + E +++   Q +K ++Q+++ Q
Sbjct: 638  EEKMQEQEEKM--WEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684



 Score =  102 bits (254), Expect = 2e-21
 Identities = 91/333 (27%), Positives = 164/333 (49%), Gaps = 41/333 (12%)

Query: 604 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
           E  Q+RL  Q+E   L++ + +Q Q+  I +Q  ++  Q++      +  +Q  +  Q+ 
Sbjct: 429 EWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486

Query: 664 QTL----KMRISDQNIIPSVTRSVSVPDTGSIWELQPTA--SQPTVWEGGSVWDLPLDTT 717
           Q      KMR  +Q +     R         +WE        +  + E   +W       
Sbjct: 487 QMWEQEEKMRDQEQKMWDQEER---------MWEQDERLREKEERMREQKKMWQQEEKMR 537

Query: 718 TPGPALEQLQQLEKAKAAKLEQER-REAEMRAKREEEERKRQEELRRQQEEILRRQ---- 772
                 EQ ++    +    E+ER RE E + + EEE  + QEE  ++QEE +R Q    
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597

Query: 773 -------QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE 825
                  QE+E K  E+EE    ++EE   +++E+ +      +EE+ Q+QEE +   EE
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMM----WEQEEKMQEQEEKMWEQEE 653

Query: 826 RRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR 884
           + RE+EE+ R+QEE ++ QEE+     RE+EE  +  EE   +M E+  ++R +EE+   
Sbjct: 654 KMREQEEKMREQEEKMQGQEEK----MREQEEKMQGQEE---KMREQEEKMRGQEEKMWG 706

Query: 885 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 917
           +E ++  Q+E M  +++ +E   R++ Q+++ Q
Sbjct: 707 QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 97/553 (17%), Positives = 233/553 (42%), Gaps = 68/553 (12%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
            AL  +    K     +E+  +E +  +          EEL+++  E+     +E+ +  E
Sbjct: 146  ALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL-----QEKLRLAE 200

Query: 782  EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 841
             E+   +   + L+R+ E+   L  Q   +    QEE  R+ EE R +E++ RKQEE + 
Sbjct: 201  SEKSEIQLNVKELKRKLERAKFLLPQ--VQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 258

Query: 842  KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 901
            +QEE        E+E + R +E ++R +E+  RLR +E+E + +E E++ QK+L  Q +Q
Sbjct: 259  RQEERL-----REQEGKMREQEEKMRRQEK--RLREQEKELREQEKELREQKKLREQEEQ 311

Query: 902  QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 961
             QE   ++ +Q+++ +  + K+     W Q+                 ++L E+      
Sbjct: 312  MQEQEEKMWEQEEKMREQEEKM-----WRQE-----------------ERLWEQ------ 343

Query: 962  EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQ 1021
            E+Q R+Q + M+  +++  +Q ++L       +         E  QEE R  +++++ ++
Sbjct: 344  EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403

Query: 1022 QHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDD 1081
            + +                   ++W         Q   +    +W     +      W+ 
Sbjct: 404  EEETMREQEEKMQKQ-----EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 458

Query: 1082 AVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQ 1141
              K         + K    + +   +  ++++  E+EEK+    Q +   ++   +  E+
Sbjct: 459  EEKIRDQEEMWGQEK---KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515

Query: 1142 MLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAK----EFAKQFLERRAK 1197
            +                  ++E +  ++  + +R       + K    +  K   E R +
Sbjct: 516  LREKEER------------MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563

Query: 1198 QKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEA 1257
            ++  + R+++++ ++Q+++  +Q  +  +Q++ +W           +      ++  +E 
Sbjct: 564  EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ--EEKMWEQEEKMWEQ 621

Query: 1258 VQSGKKKKKQKMV 1270
             +  K +++++M+
Sbjct: 622  EEEDKMQEQEEMM 634



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 79/375 (21%), Positives = 164/375 (43%), Gaps = 34/375 (9%)

Query: 483 DDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQ 542
           ++EE ++  E++ +K    + +   + E    +L E + K      M E  +K + ++ +
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461

Query: 543 GEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHM 602
              Q     QE   W Q     M     +  ++  +      KMW +            M
Sbjct: 462 IRDQEEMWGQEKKMWRQE---KMREQEDQMWEQEEKMRDQEQKMWDQ---------EERM 509

Query: 603 GELDQ---ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALL 659
            E D+   E+  R +E   ++Q +    ++   Q+Q  +   Q++K     + +++   +
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM 569

Query: 660 LQQFQTL-----KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPL 714
            ++ + +     KM+  ++ +     +     +     E +    +  +WE      +  
Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629

Query: 715 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 774
                    E++Q+ E+ K  + E++ RE E + + +EE+ + QEE  R+QEE  + Q +
Sbjct: 630 QEEMMWEQEEKMQEQEE-KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE--KMQGQ 686

Query: 775 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 834
           EE+ R +EE++  R QEE +  Q E      +   +EE+   +E +R  EER R+++E  
Sbjct: 687 EEKMREQEEKM--RGQEEKMWGQEE------KMWGQEEKMWGQEEMREKEERIRDQKE-- 736

Query: 835 KQEELLRKQEEEAAK 849
           K +E L + EE  ++
Sbjct: 737 KMQERLPEHEERCSE 751



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 90/508 (17%), Positives = 196/508 (38%), Gaps = 51/508 (10%)

Query: 781  EEEELARRKQEEALRRQREQE------IALRRQREEEERQQQEEALRRLEERRREEEERR 834
            E+E+ A  + +EALRR+ E +      +  ++   E      ++A R+ E+    E +  
Sbjct: 70   EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129

Query: 835  KQE--------ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 886
                         L++     + W ++ +     L + R  +  E  R     EE K+K 
Sbjct: 130  AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189

Query: 887  LEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL 946
             E+  Q++L     ++ E    +++ +++ + A+  LP   T   Q      + +     
Sbjct: 190  AEL--QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247

Query: 947  AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             +I+K EE+  RQ  EE+ R+Q   M+  +++ ++Q+++L       +     K L E +
Sbjct: 248  KKIRKQEEKMWRQ--EERLREQEGKMREQEEKMRRQEKRLREQEKELREQ--EKELREQK 303

Query: 1007 QEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVW-GSINTGPPNQWASDLVSSI 1065
            +   ++ Q Q+Q+++  +Q  + R              +W          Q   D    +
Sbjct: 304  KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE--ERLWEQEKQMREQEQKMRDQEERM 361

Query: 1066 WSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLF 1125
            W   +             KE   R      +    + +   +  R+ K  EEEE + +  
Sbjct: 362  WEQDERLRE---------KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE 412

Query: 1126 QGVNKAQDGF-----TQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD 1180
            + + K ++        +W +Q L           P     L E E   E  + I      
Sbjct: 413  EKMQKQEENMWEQEEKEWQQQRL-----------PEQKEKLWEQEKMQEQEEKIWEQEEK 461

Query: 1181 TSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLH 1240
              + +E   Q  E++  ++   + Q+ Q+ +Q+++   Q+  +   Q++ +W  +     
Sbjct: 462  IRDQEEMWGQ--EKKMWRQEKMREQEDQMWEQEEKMRDQE-QKMWDQEERMWEQDERLRE 518

Query: 1241 SVFQTNQSNNQQSNFEAVQSGKKKKKQK 1268
               +  +        E ++  KK ++Q+
Sbjct: 519  KEERMREQKKMWQQEEKMREEKKTQEQE 546



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 46/232 (19%), Positives = 95/232 (40%), Gaps = 22/232 (9%)

Query: 190 VGRKHEFIRSESENW----RIFREEQNGEDEDGGWRLAGSRRDGER--WRPHSPDGPRSA 243
           +  + E IR + E W    +++R+E+  E ED  W      RD E+  W        +  
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514

Query: 244 GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSS 303
             RE  ER R  +  ++  +  R  ++ +       D  + + E      EE M   +  
Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE------EERMREREK- 567

Query: 304 GAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVG 363
                 K  ++E +  EQE   +  ++ E+  + E    E+ ++  +  +K  E+ +++ 
Sbjct: 568 ------KMREEEEMMREQEEKMQ--EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619

Query: 364 VEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRME 415
            E  EE                 Q QE   +E++++ + ++ +  E+E +M+
Sbjct: 620 -EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A member
            6-like protein 6 [Homo sapiens]
          Length = 655

 Score =  134 bits (337), Expect = 6e-31
 Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)

Query: 608  ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 667
            E+LT++++  +L              + Y   +  ++    +++ Q++L L+  +   ++
Sbjct: 193  EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238

Query: 668  MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 718
            + + D        Q ++P     V     G   ELQ  +++     E   +W+L      
Sbjct: 239  LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291

Query: 719  PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778
                 E+    ++ K  + E++  E E++ + +EE+  RQEE   +QEE +R Q  E++ 
Sbjct: 292  -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348

Query: 779  RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 833
             R+EE++  R+QEE +R Q E    QE  +R Q  +E+ Q+QEE + R EE+ RE+EE+ 
Sbjct: 349  WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404

Query: 834  -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 880
                       R+Q+E +R+QEEE   W +EE+  E +  +++   ++ E   +++ EEE
Sbjct: 405  QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 938
            + + +E ++QRQ+E +++++++     +L +Q+++  +Q  +M       W Q+      
Sbjct: 463  KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519

Query: 939  QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 997
            Q Q      + +K+ E+  R  ++E++ Q++E+ ++ L+++  +  QK    G   + SG
Sbjct: 520  QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579

Query: 998  TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1025
            + +         +E++ +EA+ +Q+QQ   + H Q
Sbjct: 580  SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614



 Score =  110 bits (275), Expect = 9e-24
 Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)

Query: 727 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 780
           +Q EK +  + E  R+E ++R + E+ + K  RQE+  R+Q+E +R Q+EE    E K R
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437

Query: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
           E EE+ +  QEE LR     E+  + Q EEE+ Q+QEE ++R EE+ +E+EE+  ++E L
Sbjct: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491

Query: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 899
            KQEE+   W  E+EE   R EE   +M E+  +++ +EE+ +R+E +++ Q+  L +Q 
Sbjct: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544

Query: 900 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 959
           ++ QE   RLQ+ +++      K       G++S +    +   +   E++  E +  +Q
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604

Query: 960 LREEQRRQQRELMKALQQ 977
            ++  R   ++ + A QQ
Sbjct: 605 QQDHYRGHLQQYVAAYQQ 622



 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)

Query: 724 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
           E++++ E+ +  K+   E++ RE + + + +EEE  RQEE  R+ EE++   Q++E K R
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451

Query: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
           E EE   + QEE  + Q ++E   + QR+EE+ Q+QEE   R E+  ++EE+  +QEE +
Sbjct: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505

Query: 841 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
            +QEE+   W +EE  +E + +++    +M E+  RL  +EE+ + +E+ +Q  +E + +
Sbjct: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563

Query: 899 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
             Q+ E L    ++   Q+L       Q++L S      Q      +      +A  Q+L
Sbjct: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623

Query: 953 EEERE 957
              +E
Sbjct: 624 ASGKE 628


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A member
            6-like protein 6 [Homo sapiens]
          Length = 655

 Score =  134 bits (337), Expect = 6e-31
 Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)

Query: 608  ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 667
            E+LT++++  +L              + Y   +  ++    +++ Q++L L+  +   ++
Sbjct: 193  EKLTKERDALSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238

Query: 668  MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 718
            + + D        Q ++P     V     G   ELQ  +++     E   +W+L      
Sbjct: 239  LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291

Query: 719  PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778
                 E+    ++ K  + E++  E E++ + +EE+  RQEE   +QEE +R Q  E++ 
Sbjct: 292  -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348

Query: 779  RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 833
             R+EE++  R+QEE +R Q E    QE  +R Q  +E+ Q+QEE + R EE+ RE+EE+ 
Sbjct: 349  WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404

Query: 834  -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 880
                       R+Q+E +R+QEEE   W +EE+  E +  +++   ++ E   +++ EEE
Sbjct: 405  QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 938
            + + +E ++QRQ+E +++++++     +L +Q+++  +Q  +M       W Q+      
Sbjct: 463  KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519

Query: 939  QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 997
            Q Q      + +K+ E+  R  ++E++ Q++E+ ++ L+++  +  QK    G   + SG
Sbjct: 520  QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579

Query: 998  TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1025
            + +         +E++ +EA+ +Q+QQ   + H Q
Sbjct: 580  SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614



 Score =  110 bits (275), Expect = 9e-24
 Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)

Query: 727 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 780
           +Q EK +  + E  R+E ++R + E+ + K  RQE+  R+Q+E +R Q+EE    E K R
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437

Query: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
           E EE+ +  QEE LR     E+  + Q EEE+ Q+QEE ++R EE+ +E+EE+  ++E L
Sbjct: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491

Query: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 899
            KQEE+   W  E+EE   R EE   +M E+  +++ +EE+ +R+E +++ Q+  L +Q 
Sbjct: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544

Query: 900 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 959
           ++ QE   RLQ+ +++      K       G++S +    +   +   E++  E +  +Q
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604

Query: 960 LREEQRRQQRELMKALQQ 977
            ++  R   ++ + A QQ
Sbjct: 605 QQDHYRGHLQQYVAAYQQ 622



 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)

Query: 724 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
           E++++ E+ +  K+   E++ RE + + + +EEE  RQEE  R+ EE++   Q++E K R
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451

Query: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
           E EE   + QEE  + Q ++E   + QR+EE+ Q+QEE   R E+  ++EE+  +QEE +
Sbjct: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505

Query: 841 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
            +QEE+   W +EE  +E + +++    +M E+  RL  +EE+ + +E+ +Q  +E + +
Sbjct: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563

Query: 899 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
             Q+ E L    ++   Q+L       Q++L S      Q      +      +A  Q+L
Sbjct: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623

Query: 953 EEERE 957
              +E
Sbjct: 624 ASGKE 628


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 436

 Score =  134 bits (336), Expect = 7e-31
 Identities = 101/332 (30%), Positives = 176/332 (53%), Gaps = 37/332 (11%)

Query: 720  GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQ---- 773
            G   EQ  Q+ + +    EQE   RE E + + +E + + QE   R+QE  +R Q+    
Sbjct: 108  GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167

Query: 774  EEERKRREEEELARR-------------KQEEALRRQREQ--EIALRRQREEEERQQQEE 818
            E+E + RE+E   R              +QE  +  Q EQ  E   + Q++EE+  +QEE
Sbjct: 168  EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227

Query: 819  ALRRLEERRREEEER-RKQEELLRKQEEEAAK---WAREEEEAQRRLEENRLRMEEEAAR 874
             +R+ EE+  E+EE+ +KQEE ++KQEE+  K     RE+EE  R  EE  L+ +E+   
Sbjct: 228  QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT-- 285

Query: 875  LRHEEEERKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQ 931
               +EE+   +E +++ Q+E MR++++Q   QE   R Q++Q  +Q  QM       W Q
Sbjct: 286  --EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ 343

Query: 932  QSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGN 991
            +      + Q      ++QK EE+  +Q  EEQ R+Q E M+  ++Q ++Q++++   G 
Sbjct: 344  KEQMWKQEEQMGEQEEQMQKQEEQVRKQ--EEQMRKQEEQMRKQEEQMRKQEEQM---GE 398

Query: 992  VSKPSGTTKSLLEIQQEEARQMQKQQQQQQQH 1023
              +  G  K  +  Q+E+  + ++Q ++Q++H
Sbjct: 399  QKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430



 Score =  128 bits (322), Expect = 3e-29
 Identities = 102/410 (24%), Positives = 210/410 (51%), Gaps = 45/410 (10%)

Query: 581 GDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVL 640
           G + +  G+V    G          +QE   R+QE     Q   ++ Q+  +++Q  QV 
Sbjct: 66  GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125

Query: 641 AQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQ 700
            Q+ +     +Q+ Q+     Q +  + ++ +Q               G + E +    +
Sbjct: 126 EQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182

Query: 701 PTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE 760
               + G V +        G    Q+ + E+    + EQ +++ E   ++EE+ RK++E+
Sbjct: 183 ----QEGQVRE---QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235

Query: 761 LRRQQEEILRR----QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-Q 815
           +  Q+E++ ++    Q++EE+ R++EE++  R+QEE +R Q EQ +  + Q E+EE+  +
Sbjct: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQM--REQEEQMREQEEQMLKQKEQTEQEEQTGE 293

Query: 816 QEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 874
           QEE +R  EE+ RE+EE+ R+QEE +R+QEE+  K   +  E + ++ E + +M ++  +
Sbjct: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353

Query: 875 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 934
           +  +EE+ +++E +V++Q+E MR++++Q     R Q++Q ++Q  QM        G+Q  
Sbjct: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQM----RKQEEQMRKQEEQM--------GEQKE 401

Query: 935 TTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
                          Q  E++ + + +EEQ  +Q+E M+  ++   +Q++
Sbjct: 402 ---------------QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436



 Score =  119 bits (299), Expect = 1e-26
 Identities = 93/315 (29%), Positives = 162/315 (51%), Gaps = 51/315 (16%)

Query: 720  GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777
            G   EQ  Q+ + +    EQE   RE E + + +E + + QE   R+QE  +R Q+ + R
Sbjct: 129  GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188

Query: 778  KRRE---EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER- 833
            ++     E+E    +QEE +  Q EQ      Q++EE+  +QEE +R+ EE+  E+EE+ 
Sbjct: 189  EQEGQMGEQEGQMGEQEEQMGEQEEQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243

Query: 834  RKQEELLRKQEEEAAKWA---REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
            +KQEE ++KQEE+  K     RE+EE  R  EE  L+ +E+      +EE+   +E +++
Sbjct: 244  QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT----EQEEQTGEQEEQMR 299

Query: 891  RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 950
             Q+E MR++++Q     R Q++Q ++Q  QM       W Q+      + Q  +   E Q
Sbjct: 300  EQEEQMREQEEQM----REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ--MWKQEEQ 353

Query: 951  KLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEA 1010
              E+E + Q +EEQ R+Q E M+  ++Q ++Q++                          
Sbjct: 354  MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE-------------------------- 387

Query: 1011 RQMQKQQQQQQQHQQ 1025
             QM+KQ++Q  + ++
Sbjct: 388  -QMRKQEEQMGEQKE 401



 Score =  108 bits (269), Expect = 4e-23
 Identities = 88/317 (27%), Positives = 166/317 (52%), Gaps = 20/317 (6%)

Query: 720  GPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777
            G   EQ  Q+ + +    EQE   RE E + + +E + + QE   R+QE  +R Q+ + R
Sbjct: 52   GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 111

Query: 778  KRREEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER 833
                E+E   R+QE  +R Q    REQE  +R Q  E + ++QE  +R  E + RE+E +
Sbjct: 112  ----EQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQ 165

Query: 834  -RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892
             R+QE  +R+QE +  +   +  E + ++ E   +M E+  ++  +EE+ +++E ++  Q
Sbjct: 166  VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225

Query: 893  KELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 949
            +E MR++++Q   QE   + Q++Q Q+Q  QM+        Q+      + Q    L + 
Sbjct: 226  EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM---LKQK 282

Query: 950  QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL-SGWGNVSKPSGTTKSLLEIQQE 1008
            ++ E+E +   +EEQ R+Q E M+  ++Q ++Q++++      + K         E   E
Sbjct: 283  EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342

Query: 1009 EARQMQKQQQQQQQHQQ 1025
            +  QM KQ++Q  + ++
Sbjct: 343  QKEQMWKQEEQMGEQEE 359



 Score =  105 bits (263), Expect = 2e-22
 Identities = 83/318 (26%), Positives = 167/318 (52%), Gaps = 27/318 (8%)

Query: 730  EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR---EEEELA 786
            ++ +  + E + RE E + + +E + + QE   R+QE  +R Q+ + R++     E+E  
Sbjct: 50   QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 109

Query: 787  RRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEELLR 841
             R+QE  +R Q    REQE  +R Q  E + ++QE  +R  E + RE+E + R+QE  +R
Sbjct: 110  VREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167

Query: 842  KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 901
            +QE +  +   +  E + ++ E   +M E+  ++  +EE+   +E ++Q+Q+E M ++++
Sbjct: 168  EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227

Query: 902  Q----------QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK 951
            Q          QE   + Q++Q Q+Q  QM+        Q+      + Q      + ++
Sbjct: 228  QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287

Query: 952  LEE--ERERQLR--EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007
             E+  E+E Q+R  EEQ R+Q E M+  ++Q ++Q++++   G   +     K  +  Q+
Sbjct: 288  EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM---GKQEEQMWEQKEQMWEQK 344

Query: 1008 EEARQMQKQQQQQQQHQQ 1025
            E+  + ++Q  +Q++  Q
Sbjct: 345  EQMWKQEEQMGEQEEQMQ 362



 Score =  103 bits (258), Expect = 8e-22
 Identities = 82/314 (26%), Positives = 166/314 (52%), Gaps = 17/314 (5%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR-RQQEEILRRQQEEERKRREE 782
            E  ++L+  +  K E +    E++ K E ++    +E + R+QE  +R Q+ + R    E
Sbjct: 15   ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR----E 70

Query: 783  EELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQE 837
            +E   R+QE  +R Q    REQE  +R Q  E + ++QE  +R  E + RE+E + R+QE
Sbjct: 71   QEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVREQEGQVREQE 128

Query: 838  ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897
              +R+QE +  +   +  E + ++ E   ++ E+  ++R +E + + +E +V+ Q+  +R
Sbjct: 129  GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188

Query: 898  QRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 954
            +++ Q   QE     Q++Q  +Q  QM+        Q+      + Q      ++QK EE
Sbjct: 189  EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248

Query: 955  ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQ 1014
            + ++Q  EEQ R+Q E M+  ++Q ++Q++++      ++    T    E  +E+  QM+
Sbjct: 249  QVQKQ--EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306

Query: 1015 KQQQQQQQHQQPNR 1028
            +Q++Q ++ ++  R
Sbjct: 307  EQEEQMREQEEQMR 320



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 75/284 (26%), Positives = 147/284 (51%), Gaps = 12/284 (4%)

Query: 751  EEEERKRQEELRRQQEEILRRQQE-EERKRREEEELARRKQEEALRRQ----REQEIALR 805
            +E+  + QEEL+  + E    Q   +E KR+ E +     QE  +R Q    REQE  +R
Sbjct: 10   KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69

Query: 806  RQREEEERQQQEEALRRLEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEEN 864
             Q  E + ++QE  +R  E + RE+E + R+QE  +R+QE +  +   +  E + ++ E 
Sbjct: 70   EQ--EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127

Query: 865  RLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ---QQQEALRRLQQQQQQQQLAQM 921
              ++ E+  ++R +E + + +E +V+ Q+  +R+++   ++QE   R Q+ Q ++Q  Q+
Sbjct: 128  EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187

Query: 922  KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQ 981
            +        Q+      + Q      ++QK EE+   Q  E+ R+Q+ ++ +  +Q Q+Q
Sbjct: 188  REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ-EEQMRKQEEQMGEQEEQVQKQ 246

Query: 982  QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1025
            ++Q       + K     +   E  +E+  QM KQ++Q +Q +Q
Sbjct: 247  EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290



 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 83/454 (18%), Positives = 202/454 (44%), Gaps = 39/454 (8%)

Query: 773  QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ-QQEEALRRLEERRREEE 831
            +E+  + +EE +L   ++ E     +E    L+R+ E ++    QE  +R  E + RE+E
Sbjct: 10   KEKNAELQEELQLVETEKSEIQLHIKE----LKRKLETDKIPLPQEGQVREQEGQVREQE 65

Query: 832  ER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
             + R+QE  +R+QE +  +   +  E + ++ E   ++ E+  ++R +E + + +E +V+
Sbjct: 66   GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125

Query: 891  RQKELMRQRQ---QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947
             Q+  +R+++   ++QE   R Q+ Q ++Q  Q++        Q+      + Q      
Sbjct: 126  EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185

Query: 948  EIQKLE---EERERQL--REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1002
            ++++ E    E+E Q+  +EEQ  +Q E M+  ++Q  +Q++++       +  G  +  
Sbjct: 186  QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR---KQEEQMGEQEEQ 242

Query: 1003 LEIQQEEARQMQKQ--QQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASD 1060
            ++ Q+E+ ++ ++Q  +Q++Q  +Q  + R      L             TG   +   +
Sbjct: 243  VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK--EQTEQEEQTGEQEEQMRE 300

Query: 1061 LVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEK 1120
                +    +          +  +++G +      +      +   +  ++ +  E+EE+
Sbjct: 301  QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360

Query: 1121 LLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGD 1180
            + K  + V K ++   +  EQM                   K+ E   +  + +      
Sbjct: 361  MQKQEEQVRKQEEQMRKQEEQM------------------RKQEEQMRKQEEQMGEQKEQ 402

Query: 1181 TSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQ 1214
              E KE  ++  E+  +QK   ++Q++ + +Q++
Sbjct: 403  MGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 78/478 (16%), Positives = 196/478 (41%), Gaps = 89/478 (18%)

Query: 822  RLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 881
            R+     +E+    QEEL +  E E ++     +E +R+LE +++ + +E  ++R +E +
Sbjct: 3    RITNEELKEKNAELQEEL-QLVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQEGQ 60

Query: 882  RKRKELEVQRQKELMRQRQQQ---QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
             + +E +V+ Q+  +R+++ Q   QE   R Q+ Q ++Q  Q++        Q+      
Sbjct: 61   VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120

Query: 939  QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998
            + Q      +++    E+E Q+RE++ + + +  +  +Q+ Q ++Q+    G V +  G 
Sbjct: 121  EGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQVREQE----GQVREQEG- 171

Query: 999  TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1058
                 +++++E +  +++ Q ++Q  Q                                 
Sbjct: 172  -----QVREQEGQVREQEGQVREQEGQMGE------------------------------ 196

Query: 1059 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1118
                         +   MG   +  +++G +    + +      +   +  ++ +  E+E
Sbjct: 197  -------------QEGQMG---EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240

Query: 1119 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1178
            E++ K  + V K ++   +  EQM                   ++ E   E  + +    
Sbjct: 241  EQVQKQEEQVQKQEEQMRKQEEQMR------------------EQEEQMREQEEQMLKQK 282

Query: 1179 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1238
              T + ++  +Q  E + +++  Q R+Q++  ++Q++Q  +Q  Q  +Q++ +W      
Sbjct: 283  EQTEQEEQTGEQ--EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340

Query: 1239 LHSV----FQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGE 1292
                     Q  Q   Q+   +  +   +K++++M + +  +         +   MGE
Sbjct: 341  WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 34/203 (16%), Positives = 81/203 (39%), Gaps = 14/203 (6%)

Query: 246 REHMERRRRFEFDFRDRD----DERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFD 301
           RE   + R  E   R+++    ++ G  R + G     + +    E  + + EE+MG  +
Sbjct: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE 212

Query: 302 SSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNK-----KEG 356
                  ++K +++   +E++M  +    GE+    +    +  K+ ++  K     +E 
Sbjct: 213 EQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ 267

Query: 357 EKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMEN 416
           E+  R   E   +  + +    + G   +   ++  Q   ++E   EQ E+  E+     
Sbjct: 268 EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMG 327

Query: 417 SLPAKVPSRGDEMVADVQQPLSQ 439
               ++  + ++M    +Q   Q
Sbjct: 328 KQEEQMWEQKEQMWEQKEQMWKQ 350



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 31/197 (15%), Positives = 78/197 (39%), Gaps = 8/197 (4%)

Query: 246 REHMERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGA 305
           RE   + R  E   R+++ +     VR   G + +    + E   +  E+E    +  G 
Sbjct: 90  REQEGQVREQEGQVREQEGQ-----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 144

Query: 306 FLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVG-- 363
               +   +E   + +E + +  ++  +  + EG   E+  +  +   + GE+  ++G  
Sbjct: 145 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204

Query: 364 -VEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKV 422
             +  E+  Q      + G   +   ++  Q   ++E   +Q E+ +++         ++
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264

Query: 423 PSRGDEMVADVQQPLSQ 439
             + ++M    +Q L Q
Sbjct: 265 REQEEQMREQEEQMLKQ 281


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
            sapiens]
          Length = 668

 Score =  127 bits (320), Expect = 5e-29
 Identities = 105/431 (24%), Positives = 215/431 (49%), Gaps = 75/431 (17%)

Query: 609  RLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKM 668
            RL +QQE     Q + +Q  +  IQ+Q  ++  Q++K     ++ ++   ++ + +  KM
Sbjct: 293  RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE-KM 351

Query: 669  RISDQNIIPSVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGPALEQL 726
            R  ++                 +WE +      +  +WE                  E++
Sbjct: 352  RRQEE----------------MMWEKEEKMRRLEEMMWEKE----------------EKI 379

Query: 727  QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 786
            ++LE+    K+ ++ +  E   KR+EEE+ R++E R++QE  + RQ  EE+ R +EE++ 
Sbjct: 380  RELEE----KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKI- 432

Query: 787  RRKQEEALRRQREQEIALRRQREEEERQQQEEALR------------RLEERRREEEERR 834
             R+QE+ + RQ E+     + REEE+RQ+QEE  R            R +E+  E+E+ R
Sbjct: 433  -REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491

Query: 835  KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 894
            KQEE + +QEE+      ++EE  R  EE   R EE   ++R +EE+ + +E +++ Q+E
Sbjct: 492  KQEEKVWRQEEK----MHDQEEKIREQEEKMWRQEE---KIREQEEKIREQEEKIREQEE 544

Query: 895  LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 954
            +M++++++        Q+Q++ +  + K+       ++      + +  +   E +  E+
Sbjct: 545  MMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQ 604

Query: 955  ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQ 1014
            E   Q +EE+  +Q E M   +++ Q+Q++K+             +   E   E+  +++
Sbjct: 605  EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM-------------RRQEEKMWEQEVRLR 651

Query: 1015 KQQQQQQQHQQ 1025
            +Q+++ Q+HQ+
Sbjct: 652  QQEEKMQEHQE 662



 Score =  122 bits (305), Expect = 3e-27
 Identities = 93/339 (27%), Positives = 183/339 (53%), Gaps = 40/339 (11%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER------ 777
            E++++ E+    K E+ RR  EM  ++EE+ R+ +E++  +QE+I  R+QEE+R      
Sbjct: 349  EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH-EQEKI--REQEEKRQEEEKI 405

Query: 778  ---KRREEEELARRKQEEALRRQ----REQEIALRRQRE---EEERQQQEEALRRLEERR 827
               ++R+E+E    +QEE +R Q    REQE  + RQ E   E+E+ ++EE  +  EE  
Sbjct: 406  REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465

Query: 828  REEEERRKQEELLRKQEE--EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 885
            R+EE+ R+QEE+ R++E+  E  K  ++EE+  R+ E    +M ++  ++R +EE+  R+
Sbjct: 466  RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE----KMHDQEEKIREQEEKMWRQ 521

Query: 886  ELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLS 945
            E +++ Q+E +R   +Q+E +R  ++  Q+Q+            G+Q      Q +    
Sbjct: 522  EEKIREQEEKIR---EQEEKIREQEEMMQEQE---------EKMGEQEEKMQEQEKMRRQ 569

Query: 946  LAEIQKLEE---ERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1002
              +I++ EE   E++ ++RE++ +   +  K  +Q++  Q+Q+   W    K     + +
Sbjct: 570  EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 629

Query: 1003 LEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
             E +++  RQ +K  +Q+ + +Q          +L  +I
Sbjct: 630  QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668



 Score =  120 bits (301), Expect = 8e-27
 Identities = 93/327 (28%), Positives = 174/327 (53%), Gaps = 43/327 (13%)

Query: 727  QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQ-----------QEE 775
            QQ  +A+A  L +E +    + + + EE +    L +QQEE + RQ           QE+
Sbjct: 260  QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319

Query: 776  ERKRREEEELARRKQEEALRRQR----EQEIALRRQRE-----EEERQQQEEALRRLEER 826
            E K RE+EE   R+QEE +RRQ     E+E  +RRQ E     EE+ ++ EE +   EE+
Sbjct: 320  EEKIREQEEKI-REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378

Query: 827  RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 886
             RE EE+  ++E +R+QEE+     R+EEE   ++ E   R E+EA   R EE+ R+++E
Sbjct: 379  IRELEEKMHEQEKIREQEEK-----RQEEE---KIREQEKRQEQEAKMWRQEEKIREQEE 430

Query: 887  LEVQRQKELMRQRQQ--QQEALRRLQQQQQQQQLAQMK---LPSSSTWGQQSNTTACQSQ 941
               +++K++ RQ ++  +QE +R  +++Q+Q+++ + +         W Q+        Q
Sbjct: 431  KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK---MHEQ 487

Query: 942  ATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKS 1001
              +   E +   +E +   +EE+ R+Q E M   +++ ++Q++K      + +     + 
Sbjct: 488  EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK------IREQEEKIRE 541

Query: 1002 LLEIQQEEARQMQKQQQQQQQHQQPNR 1028
              E+ QE+  +M +Q+++ Q+ ++  R
Sbjct: 542  QEEMMQEQEEKMGEQEEKMQEQEKMRR 568



 Score =  100 bits (249), Expect = 9e-21
 Identities = 86/338 (25%), Positives = 175/338 (51%), Gaps = 40/338 (11%)

Query: 711  DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 770
            +L  +T T     E+  +L++ K   +E E+ E ++  K  + + +R + L  QQ+    
Sbjct: 208  ELYRNTITDEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---- 262

Query: 771  RQQEEERKRREEEELARRKQEEALRRQREQEIALR-RQREEEERQQQEEALRRLEERRRE 829
             Q E +   +E + ++ + Q +      E E+  R  Q++EE+  +QEE ++  EE+ +E
Sbjct: 263  LQAEADHLGKELQSVSAKLQAQV----EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318

Query: 830  EEER-RKQEELLRKQEE-----EAAKWAREE------------EEAQRRLEENRLRMEEE 871
            +EE+ R+QEE +R+QEE     E   W +EE            EE  RRLEE     EE+
Sbjct: 319  QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378

Query: 872  AARLRHE--EEERKRKELEVQRQKELMR--QRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
               L  +  E+E+ R++ E ++++E +R  +++Q+QEA    Q+++ ++Q  +++     
Sbjct: 379  IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 438

Query: 928  TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK---ALQQQQQQQQQ 984
             W Q+      +      + E +K +E+ E   +EE+ R+Q E+ +    + +Q++ ++Q
Sbjct: 439  MWRQEEKIHEQE-----KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493

Query: 985  KLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1022
            +   W    K     + + E +++  RQ +K ++Q+++
Sbjct: 494  EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK 531



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 91/510 (17%), Positives = 204/510 (40%), Gaps = 80/510 (15%)

Query: 781  EEEELARRKQEEALRRQREQEIALRR---------------------QREEEERQ----- 814
            E+E+ A  + +EALRR+ E ++   R                     Q E E R      
Sbjct: 108  EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167

Query: 815  --------QQEEALRRLEERRREE----EERRKQEELLRKQEEEAAKWAREEEEAQRRLE 862
                    + E+AL  +  ++++     EE  K+ + L  +         E +E   +L+
Sbjct: 168  HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227

Query: 863  ENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922
            E    +E E + ++   +E KRK   ++R K L+ Q+Q Q EA    ++ Q      Q +
Sbjct: 228  EKLQLVESEKSEIQLNVKELKRK---LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284

Query: 923  LPSSSTW---GQQSNTTACQSQATLSLAE--IQKLEE---ERERQLREEQRRQQRELMKA 974
            +  +  W    QQ      + +  +   E  IQ+ EE   E+E ++RE++ + +R+    
Sbjct: 285  VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344

Query: 975  LQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ------QEEARQMQKQQQQQQQHQQPNR 1028
             +++++ ++Q+   W    K     + + E +      +E+  + +K ++Q+++ Q+  +
Sbjct: 345  WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404

Query: 1029 ARNNTHSNLHTSIGNSVW-GSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVG 1087
             R         +    +W          +   +    +W   +  +       + ++E  
Sbjct: 405  IREQEKRQEQEA---KMWRQEEKIREQEEKIREQEKKMWRQEEKIHE-----QEKIREEE 456

Query: 1088 PRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALN 1147
             R    +        +      RQ +K+ E+EK+ K  + V + ++      E++     
Sbjct: 457  KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516

Query: 1148 TANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQ---- 1203
                          ++ E   E  + IR       E +E  ++  E+  +Q+   Q    
Sbjct: 517  -----------KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565

Query: 1204 -RQQQQLPQQQQQQPPQQPPQQPQQQDSVW 1232
             R+Q++  ++Q+++  +Q  +  +Q++ +W
Sbjct: 566  MRRQEEKIREQEEKIREQKEKIREQEEKIW 595



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 53/220 (24%), Positives = 98/220 (44%), Gaps = 65/220 (29%)

Query: 606 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
           DQE   R+QE     Q + ++ Q+  I++Q  ++  Q++   +  +Q++++    ++ Q 
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE---MMQEQEEKMGEQEEKMQE 562

Query: 666 L-KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 724
             KMR  ++ I                                                 
Sbjct: 563 QEKMRRQEEKI------------------------------------------------- 573

Query: 725 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQ----EEERKRR 780
             +Q EK +  K  ++ RE E +   +EE+ + QEE+ ++QEE +  Q+    E+E K +
Sbjct: 574 -REQEEKIREQK--EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 630

Query: 781 EEEELARRKQEEALRRQREQEIALRRQREE-EERQQQEEA 819
           E+EE  RR++E    +  EQE+ LR+Q E+ +E Q+  EA
Sbjct: 631 EQEEKMRRQEE----KMWEQEVRLRQQEEKMQEHQEHLEA 666



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 73/410 (17%), Positives = 162/410 (39%), Gaps = 49/410 (11%)

Query: 869  EEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST 928
            +E+ A  +H+E  R+  E +V   + L  Q+ + Q AL   Q   +Q +     L S   
Sbjct: 109  DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL- 167

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERE-RQLREEQRRQQRELMK------ALQQQQQQ 981
                S   A + +  LS    QK + +R   +L +E+     EL +       L+++  +
Sbjct: 168  --HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225

Query: 982  QQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
             Q+KL    +           L+ + E A+ +  QQQ Q +     +   +  + L   +
Sbjct: 226  LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285

Query: 1042 G-NSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS 1100
              N +W  +N     +        +W   +        W++ ++E   +    + K    
Sbjct: 286  EENELWNRLNQQQEEK--------MWRQEEKIQE----WEEKIQEQEEKIREQEEKIREQ 333

Query: 1101 LSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSF 1160
              K      RQ + + E+E+ ++  + +   ++   +  E+M+                 
Sbjct: 334  EEKM----RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK----------- 378

Query: 1161 LKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1220
            ++E+E      + IR       E ++  +Q  E+R +Q+A   RQ++++ +Q+++   Q+
Sbjct: 379  IRELEEKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKMWRQEEKIREQEEKIREQE 436

Query: 1221 PPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMV 1270
                 Q++          +H   +  +   +Q   E  +  +K ++Q+ +
Sbjct: 437  KKMWRQEE---------KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 52/285 (18%), Positives = 114/285 (40%), Gaps = 33/285 (11%)

Query: 154 EMHRSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESEN--------WR 205
           +MH  +   E+ ++R E+   ++  +   +E     + R+ E IR + E         WR
Sbjct: 385 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEA---KMWRQEEKIREQEEKIREQEKKMWR 441

Query: 206 I---------FREEQNGEDEDGGWRLAGSRRDGER-WRP----HSPDGPRSAG---WREH 248
                      REE+  ++++  WR     R+ E  WR     H  +  R      WR+ 
Sbjct: 442 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE 501

Query: 249 MERRRRFEFDFRDRDDE--RGYRRVRSGSGSIDDDRDSLPEW--CLEDAEEEMGTFDSSG 304
            E+    E   R+++++  R   ++R     I +  + + E    +++ EE+MG  +   
Sbjct: 502 -EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 560

Query: 305 AFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGV 364
                 + Q+E I E++E      ++  E  +      E+ +E ++  +++ EK      
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620

Query: 365 EASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAE 409
           +  E+  +      +     +   ++  +  +++E   E  E  E
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
            [Homo sapiens]
          Length = 914

 Score =  120 bits (301), Expect = 8e-27
 Identities = 95/306 (31%), Positives = 164/306 (53%), Gaps = 36/306 (11%)

Query: 741  RREAEMRAKREEEERKRQEELRRQQE-EILRRQQEEERKRREEEELARRKQEEALRRQRE 799
            +R   +R   +E+ER+R E LRR++E E LRRQ+ EE KRR  EE+ + K+EE LR+  +
Sbjct: 521  KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQ 579

Query: 800  QEIALRRQREEEERQ------QQEEALRRLEERRREEEERRK--------QEELLRKQEE 845
                + + +EE+++Q      Q +E   + +E R  EE+ +K        + E  RKQEE
Sbjct: 580  ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639

Query: 846  EA--AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 903
            EA   +W ++EEE +R  E  + + EEE  RLR   E ++  E   Q ++E  R+ Q+++
Sbjct: 640  EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699

Query: 904  EALRRLQQ-QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK-LEEERERQLR 961
            E  RR Q+ ++Q++QLA+          Q+      + QA   L E +K L  ++E+  R
Sbjct: 700  EQERREQERREQERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQR 749

Query: 962  E-EQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            E E+++++ E  +  ++Q Q++Q+K        + +G +K+L      ++      Q   
Sbjct: 750  ELEEKKKKEEQQRLAERQLQEEQEK-----KAKEAAGASKALNVTVDVQSPACTSYQMTP 804

Query: 1021 QQHQQP 1026
            Q H+ P
Sbjct: 805  QGHRAP 810



 Score =  115 bits (288), Expect = 3e-25
 Identities = 87/291 (29%), Positives = 157/291 (53%), Gaps = 32/291 (10%)

Query: 694 LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLE-KAKAAKLEQERREAEMRAKREE 752
           + PT++  +V +     + PL         ++L+ L  K +A +L +++ E + R + EE
Sbjct: 506 MTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEE 565

Query: 753 EERKRQEELRR--QQEEILRRQQEEERKRREE------EELARRKQEEALRRQREQEIAL 804
            + KR+E LR+  Q  E + + +EE++K+ E+      E+  + K+E     + +++ A 
Sbjct: 566 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 625

Query: 805 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEEN 864
           ++  E E R++QEE  RRL   ++EEEERR QE L +K+EE                E+ 
Sbjct: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE----------------EQE 669

Query: 865 RLRMEEEAARLRHE-EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 923
           RLR   EA RL  + E+ER+ +E   Q ++E  R+ Q+++E  R+L +Q+++++  Q +L
Sbjct: 670 RLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE--QERL 727

Query: 924 PSSSTWGQQSNTTACQ-SQATLSLAEIQKLEEER---ERQLREEQRRQQRE 970
            +     ++      Q  Q    L E +K EE++   ERQL+EEQ ++ +E
Sbjct: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778



 Score = 81.6 bits (200), Expect = 4e-15
 Identities = 48/133 (36%), Positives = 85/133 (63%), Gaps = 11/133 (8%)

Query: 729 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE----E 784
           L+K K  + E+ R+ AE +   E+ E++R+E+ RR+QE   R Q+  E++RRE+E    E
Sbjct: 660 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER--REQERREQERREQERQLAE 717

Query: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
             RR+++E L+ +RE +     +RE+  R Q+E+  R LEE++++EE++R  E  L++++
Sbjct: 718 QERRREQERLQAERELQ-----EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 772

Query: 845 EEAAKWAREEEEA 857
           E+ AK A    +A
Sbjct: 773 EKKAKEAAGASKA 785



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 78/375 (20%), Positives = 163/375 (43%), Gaps = 70/375 (18%)

Query: 693  ELQPTAS-QPTVWE--GGSVW---DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM 746
            E +P A+ +P V E  G + W   D  +  +TP P        E   A + E +  +A+ 
Sbjct: 381  EAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPK-PAASSPETPSAGQQEAKTDQAD- 438

Query: 747  RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 806
               RE  +  R+   +R  ++ +    EE+    EE +  R K   +     +    LR 
Sbjct: 439  -GPREPPQSARR---KRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494

Query: 807  QREEEERQQQ------------EEALRRLEERRRE--EEERRKQEELLRKQEEEAAKWAR 852
                 +R Q             +  ++R    R +  E+ER++ E L RK+E E  +  +
Sbjct: 495  FLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQK 554

Query: 853  EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 912
             EE+ +RRLEE +L+            EER RK L+ + + E M++ +++Q   +  Q  
Sbjct: 555  VEEDKRRRLEEVKLK-----------REERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603

Query: 913  QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE-- 970
            ++ ++  + +L                       AE +  ++   +++ E + R+++E  
Sbjct: 604  EKTEKAKEERL-----------------------AEEKAKKKAAAKKMEEVEARRKQEEE 640

Query: 971  --LMKALQQQQQQQ------QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1022
               ++ LQQ+++++      Q+K        + +   K L E +++E R+ ++++Q++++
Sbjct: 641  ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700

Query: 1023 HQQPNRARNNTHSNL 1037
             ++  + R      L
Sbjct: 701  QERREQERREQERQL 715



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 102/524 (19%), Positives = 191/524 (36%), Gaps = 108/524 (20%)

Query: 348 PDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA--SQFERKDEPKTEQT 405
           PD  +   G +TD   V  S   P + S        S    QE+   +  R+   KT + 
Sbjct: 287 PDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEE 346

Query: 406 EKAEEE----TRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVP----- 456
             A       + +E  L  +VP +    V   Q+     P + A P+    P VP     
Sbjct: 347 PAASGRIICHSYLERLLNVEVPQK----VGSEQKE----PPEEAEPVAAAEPEVPENNGN 398

Query: 457 ---------------NPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAY 501
                          NP P     ETP       G    + D  +G +   Q A +  +Y
Sbjct: 399 NSWPHNDTEIANSTPNPKPAASSPETP-----SAGQQEAKTDQADGPREPPQSARRKRSY 453

Query: 502 LQD-SALDDERLAS--KLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN-------- 550
            Q  S LD+E+     +LQ  R+K  S P             P  ++  P          
Sbjct: 454 KQAVSELDEEQHLEDEELQPPRSKTPSSPC------------PASKVVRPLRTFLHTVQR 501

Query: 551 NQEMAEWFQAGYFTMSLLVKRAC-------DESFQPLGDIMKMWGRVPFSPGPAPPPHMG 603
           NQ +     A    M   +KR         ++  Q L ++ +                  
Sbjct: 502 NQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRR 561

Query: 604 ELDQERLTRQQELTALYQM-----QHLQYQQFLIQQQYAQV-----LAQQQKAALSSQQQ 653
            L++ +L R++ L  + Q      Q  + ++  I+Q++AQ+      A++++ A    ++
Sbjct: 562 RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK 621

Query: 654 QQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLP 713
           +  A  +++ +  + +  +   +  + +         + + +    Q  + +      L 
Sbjct: 622 KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLA 681

Query: 714 LDTTTPGPALEQLQQLEKAKAAKLEQERREAE--------------MRAKREEEERKR-- 757
                     E+ +Q E+ +  + EQERRE E              ++A+RE +ER++  
Sbjct: 682 EQREQERREQERREQ-ERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 740

Query: 758 ---QEELRRQQEE---------ILRRQQEEERKRREEEELARRK 789
              +E+L+R+ EE         +  RQ +EE++++ +E     K
Sbjct: 741 RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 21/93 (22%), Positives = 50/93 (53%), Gaps = 1/93 (1%)

Query: 1178 LGDTSEAKEFAKQF-LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNH 1236
            L   +EAK  A+Q   ERR +++  Q+R++Q+  +Q++++  +Q  +Q ++++       
Sbjct: 671  LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730

Query: 1237 STLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1269
              L    +  +   +Q   E  +  KK+++Q++
Sbjct: 731  RELQEREKALRLQKEQLQRELEEKKKKEEQQRL 763



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 35/168 (20%), Positives = 73/168 (43%), Gaps = 14/168 (8%)

Query: 834 RKQEELLRKQEEEAAKWARE-EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE-VQ- 890
           +K  E L   + +   W  E +EEA+R       +  E   +   ++  RK++ +  VQ 
Sbjct: 17  QKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQD 76

Query: 891 ------RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
                 R++   R+ +  Q + RRL+ +   ++LA +   + S   + +   A  + AT+
Sbjct: 77  ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATM 136

Query: 945 SLAEIQKLEEERERQL--REEQRRQQRELMKALQ---QQQQQQQQKLS 987
           +LA       E    L  + E    Q +L+  ++    ++Q  +Q ++
Sbjct: 137 ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVT 184


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
            [Homo sapiens]
          Length = 918

 Score =  116 bits (291), Expect = 1e-25
 Identities = 93/295 (31%), Positives = 159/295 (53%), Gaps = 36/295 (12%)

Query: 752  EEERKRQEELRRQQE-EILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 810
            E+ER+R E LRR++E E LRRQ+ EE KRR  EE+ + K+EE LR+  +    + + +EE
Sbjct: 536  EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQARERVEQMKEE 594

Query: 811  EERQ------QQEEALRRLEERRREEEERRKQE--------ELLRKQEEEA--AKWAREE 854
            +++Q      Q +E   + +E R  EE+ +K+         E  RKQEEEA   +W ++E
Sbjct: 595  KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 654

Query: 855  EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ-QQ 913
            EE +R  E  + + EEE  RLR   E ++  E   Q ++E  R+ Q+++E  RR Q+ ++
Sbjct: 655  EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 714

Query: 914  QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK-LEEERERQLRE-EQRRQQREL 971
            Q++QLA+          Q+      + QA   L E +K L  ++E+  RE E+++++ E 
Sbjct: 715  QERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 764

Query: 972  MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1026
             +  ++Q Q++Q+K        + +G +K+L      ++      Q   Q H+ P
Sbjct: 765  QRLAERQLQEEQEK-----KAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAP 814



 Score =  114 bits (284), Expect = 8e-25
 Identities = 83/261 (31%), Positives = 147/261 (56%), Gaps = 33/261 (12%)

Query: 723 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR--QQEEILRRQQEEERKRR 780
           LE L++ E+A+  +L +++ E + R + EE + KR+E LR+  Q  E + + +EE++K+ 
Sbjct: 542 LENLRRKEEAE--QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 599

Query: 781 EE------EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 834
           E+      E+  + K+E     + +++ A ++  E E R++QEE  RRL   ++EEEERR
Sbjct: 600 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 659

Query: 835 KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE-EEERKRKELEVQRQK 893
            QE L +K+EE                E+ RLR   EA RL  + E+ER+ +E   Q ++
Sbjct: 660 HQELLQKKKEE----------------EQERLRKAAEAKRLAEQREQERREQERREQERR 703

Query: 894 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ-SQATLSLAEIQKL 952
           E  R+ Q+++E  R+L +Q+++++  Q +L +     ++      Q  Q    L E +K 
Sbjct: 704 EQERREQERREQERQLAEQERRRE--QERLQAERELQEREKALRLQKEQLQRELEEKKKK 761

Query: 953 EEER---ERQLREEQRRQQRE 970
           EE++   ERQL+EEQ ++ +E
Sbjct: 762 EEQQRLAERQLQEEQEKKAKE 782



 Score =  104 bits (259), Expect = 6e-22
 Identities = 71/203 (34%), Positives = 117/203 (57%), Gaps = 25/203 (12%)

Query: 722 ALEQLQQLEKAKAAKLEQ-------------ERREAEMRAKREEEERKRQE-ELRRQQEE 767
           A E+++Q+++ K  ++EQ             E R AE +AK++   +K +E E RR+QEE
Sbjct: 584 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 643

Query: 768 ILRRQ---QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE 824
             RR    Q+EE +RR +E L ++K+EE  R ++  E     ++ E+ER++QE   +   
Sbjct: 644 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 703

Query: 825 ERRREEEERRKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEEER 882
           E+ R E+ERR+QE  L +QE       RE+E  +A+R L+E    +  +  +L+ E EE+
Sbjct: 704 EQERREQERREQERQLAEQERR-----REQERLQAERELQEREKALRLQKEQLQRELEEK 758

Query: 883 KRKELEVQRQKELMRQRQQQQEA 905
           K+KE E QR  E   Q +Q+++A
Sbjct: 759 KKKE-EQQRLAERQLQEEQEKKA 780



 Score =  100 bits (248), Expect = 1e-20
 Identities = 67/182 (36%), Positives = 111/182 (60%), Gaps = 14/182 (7%)

Query: 714 LDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERK----RQEELRRQQEEIL 769
           +D  T     E+L + EKAK     ++  E E R K+EEE R+    +QEE  R+ +E+L
Sbjct: 606 IDEKTEKAKEERLAE-EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 664

Query: 770 RRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE 829
           ++++EEE++R  +   A+R  E+  + +REQE   + +RE+E R+Q+    RR +ER+  
Sbjct: 665 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE----RREQERQLA 720

Query: 830 EEERRKQEELLRKQEE--EAAKWAR-EEEEAQRRLEENRLRMEEE--AARLRHEEEERKR 884
           E+ERR+++E L+ + E  E  K  R ++E+ QR LEE + + E++  A R   EE+E+K 
Sbjct: 721 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780

Query: 885 KE 886
           KE
Sbjct: 781 KE 782



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 60/240 (25%), Positives = 136/240 (56%), Gaps = 28/240 (11%)

Query: 804  LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK--WARE-----EEE 856
            + ++R+  E  +++E   +L  ++ EE++RR+ EE+  K+EE   K   ARE     +EE
Sbjct: 535  VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 594

Query: 857  AQRRLEENRLRMEEEAARLRHEE--EERKRKELEVQRQKELMRQRQQQQEA--LRRLQQQ 912
             ++++E+   +++E+  + + E   EE+ +K+   ++ +E+  +R+Q++EA  LR LQQ+
Sbjct: 595  KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 654

Query: 913  QQQ---QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 969
            +++   Q+L Q K                + +     AE ++L E+RE++ RE++RR+Q 
Sbjct: 655  EEERRHQELLQKKKEE-------------EQERLRKAAEAKRLAEQREQERREQERREQE 701

Query: 970  ELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ-EEARQMQKQQQQQQQHQQPNR 1028
               +  ++Q++++Q++        +     ++  E+Q+ E+A ++QK+Q Q++  ++  +
Sbjct: 702  RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 761



 Score = 81.6 bits (200), Expect = 4e-15
 Identities = 48/133 (36%), Positives = 85/133 (63%), Gaps = 11/133 (8%)

Query: 729 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE----E 784
           L+K K  + E+ R+ AE +   E+ E++R+E+ RR+QE   R Q+  E++RRE+E    E
Sbjct: 664 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER--REQERREQERREQERQLAE 721

Query: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
             RR+++E L+ +RE +     +RE+  R Q+E+  R LEE++++EE++R  E  L++++
Sbjct: 722 QERRREQERLQAERELQ-----EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 776

Query: 845 EEAAKWAREEEEA 857
           E+ AK A    +A
Sbjct: 777 EKKAKEAAGASKA 789



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 102/528 (19%), Positives = 191/528 (36%), Gaps = 112/528 (21%)

Query: 348 PDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA--SQFERKDEPKTEQT 405
           PD  +   G +TD   V  S   P + S        S    QE+   +  R+   KT + 
Sbjct: 287 PDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEE 346

Query: 406 EKAEEE----TRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVP----- 456
             A       + +E  L  +VP +    V   Q+     P + A P+    P VP     
Sbjct: 347 PAASGRIICHSYLERLLNVEVPQK----VGSEQKE----PPEEAEPVAAAEPEVPENNGN 398

Query: 457 ---------------NPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAY 501
                          NP P     ETP       G    + D  +G +   Q A +  +Y
Sbjct: 399 NSWPHNDTEIANSTPNPKPAASSPETP-----SAGQQEAKTDQADGPREPPQSARRKRSY 453

Query: 502 LQD-SALDDERLAS--KLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN-------- 550
            Q  S LD+E+     +LQ  R+K  S P             P  ++  P          
Sbjct: 454 KQAVSELDEEQHLEDEELQPPRSKTPSSPC------------PASKVVRPLRTFLHTVQR 501

Query: 551 NQEMAEWFQAGYFTMSLLVKRAC-----------DESFQPLGDIMKMWGRVPFSPGPAPP 599
           NQ +     A    M   +KR             ++  Q L ++ +              
Sbjct: 502 NQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEE 561

Query: 600 PHMGELDQERLTRQQELTALYQM-----QHLQYQQFLIQQQYAQV-----LAQQQKAALS 649
                L++ +L R++ L  + Q      Q  + ++  I+Q++AQ+      A++++ A  
Sbjct: 562 DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE 621

Query: 650 SQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSV 709
             +++  A  +++ +  + +  +   +  + +         + + +    Q  + +    
Sbjct: 622 KAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEA 681

Query: 710 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAE--------------MRAKREEEER 755
             L           E+ +Q E+ +  + EQERRE E              ++A+RE +ER
Sbjct: 682 KRLAEQREQERREQERREQ-ERREQERREQERREQERQLAEQERRREQERLQAERELQER 740

Query: 756 KR-----QEELRRQQEE---------ILRRQQEEERKRREEEELARRK 789
           ++     +E+L+R+ EE         +  RQ +EE++++ +E     K
Sbjct: 741 EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 788



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 21/93 (22%), Positives = 50/93 (53%), Gaps = 1/93 (1%)

Query: 1178 LGDTSEAKEFAKQF-LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNH 1236
            L   +EAK  A+Q   ERR +++  Q+R++Q+  +Q++++  +Q  +Q ++++       
Sbjct: 675  LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734

Query: 1237 STLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1269
              L    +  +   +Q   E  +  KK+++Q++
Sbjct: 735  RELQEREKALRLQKEQLQRELEEKKKKEEQQRL 767



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 35/168 (20%), Positives = 73/168 (43%), Gaps = 14/168 (8%)

Query: 834 RKQEELLRKQEEEAAKWARE-EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE-VQ- 890
           +K  E L   + +   W  E +EEA+R       +  E   +   ++  RK++ +  VQ 
Sbjct: 17  QKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQD 76

Query: 891 ------RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
                 R++   R+ +  Q + RRL+ +   ++LA +   + S   + +   A  + AT+
Sbjct: 77  ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATM 136

Query: 945 SLAEIQKLEEERERQL--REEQRRQQRELMKALQ---QQQQQQQQKLS 987
           +LA       E    L  + E    Q +L+  ++    ++Q  +Q ++
Sbjct: 137 ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVT 184


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score =  114 bits (286), Expect = 5e-25
 Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 778
            ALE+ +QL +A A    Q  REA+   +R +EE  R+EE     +QQ+  ++ + ++ R+
Sbjct: 1368 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1427

Query: 779  RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 812
              E E  A+ +Q EA  R R   E+EI                      ALR + EE E 
Sbjct: 1428 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1487

Query: 813  --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 869
              RQ QEEA  RL  + ++E +R++Q E+ L  + +  A+ ARE++ A + LEE RL+ E
Sbjct: 1488 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1546

Query: 870  EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 901
            E   RLR  E ER R+                            +LE   Q+E +   Q 
Sbjct: 1547 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1606

Query: 902  QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
            ++EA RR QQQ        + +++L + +L ++     +        Q +L+ AE +K +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666

Query: 954  EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
            EE ER+ R     EEQ  +QRE    L +Q+ ++Q++L+         GT +  L  +QE
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1714

Query: 1009 EARQMQKQQQQQQQHQ 1024
              R   + +Q +QQ Q
Sbjct: 1715 LIRLRAETEQGEQQRQ 1730



 Score =  110 bits (275), Expect = 9e-24
 Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
            ++LQQ  + + + L+Q R EAE   +  EE  + + +  R+  +  R+ +E ER ++  E
Sbjct: 2063 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2122

Query: 784  ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
            E A+ + +     E LR++ EQE A R Q E+   +Q++ A   +E+ ++  E+  +Q+ 
Sbjct: 2123 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2182

Query: 839  LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
             + +QE    +   EE + Q+ L      ++EE  RL+ E  E  R+  +V  ++EL   
Sbjct: 2183 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2233

Query: 899  RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 956
            R Q +E L +L+ + + +  A +     +T            Q     A +    +E  R
Sbjct: 2234 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292

Query: 957  ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
             RQL EE   QQR L + + +++ Q  Q+ +    +   +   +   E+ QE+AR++Q+ 
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2349

Query: 1017 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1068
            ++Q  Q         Q+   A       +                    A +        
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409

Query: 1069 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1122
            A+     +   + A +E      T + +   S      L +++    R+ +K+++E KLL
Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469

Query: 1123 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1182
            +L     K+++  T   EQ+L               SFL E +S  +   +I     + +
Sbjct: 2470 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2514

Query: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1242
            + ++  +  + +  + +  QQRQQQQ+ Q++Q+        + +Q ++  G+       +
Sbjct: 2515 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2573

Query: 1243 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1270
             Q  Q   QQ    A ++ + +++ +++
Sbjct: 2574 QQLEQQRRQQEELLAEENQRLREQLQLL 2601



 Score =  103 bits (256), Expect = 1e-21
 Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)

Query: 759  EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 816
            E LRR +EE  +  +Q+ EER+R  E E A  KQ +      + +    R+ +E +++ Q
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398

Query: 817  EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 871
            EE +RR E     ++++R  QEEL  LR+  E E    AR+ E A+R    +RLR+EEE 
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1454

Query: 872  -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 922
               RL+ E  ER+R   E E+Q    R +E   Q++Q QE   RL  Q Q + Q+  Q +
Sbjct: 1455 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1514

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
            +  +S    ++     + +A  +L E++   EE ER+LR+ +  + R++  AL+  Q+  
Sbjct: 1515 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1574

Query: 983  QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1037
            + +L         K +   +SL E     A+  ++ +++ QQ  +  RAR      L
Sbjct: 1575 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1631



 Score =  101 bits (251), Expect = 5e-21
 Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)

Query: 606  DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 662
            ++ERL  QQ   E   L +++    +Q  + + +AQ  AQ ++ A   QQ+ Q  ++ ++
Sbjct: 1346 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1405

Query: 663  FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 714
                +  +  Q    S+   +      S  E+Q  A Q    E           V  L L
Sbjct: 1406 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1461

Query: 715  DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 762
            + T    G A  +LQ L +A+A + E ++R+A+  A+R      +E +RKRQ E+     
Sbjct: 1462 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1520

Query: 763  -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 817
             + + E  R +Q      E  R + EE  RR ++  + R R+ ++AL   +   E + Q 
Sbjct: 1521 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1580

Query: 818  EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 871
            +     E+  + E   +++   + +  EEA + A+++ EA+R  EE    +E       E
Sbjct: 1581 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1640

Query: 872  AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 928
            A RLR + EE  +++   Q + E  ++ + ++EA RR + ++Q   Q++LA+ +L     
Sbjct: 1641 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1699

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
              + +      ++  L     +  + E++RQL EE+  R QRE   A Q++Q+ + +   
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1756

Query: 988  GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1020
                ++K     + LL  +   +EE+R   ++ +Q+
Sbjct: 1757 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1788



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)

Query: 613  QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 667
            +QELT L  Q++   +Q+ L+ ++  ++ A+  +AA    Q ++    + + +++   LK
Sbjct: 2185 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2244

Query: 668  MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 727
             RI  +N      R++ + D  +        ++           L +        L QL 
Sbjct: 2245 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2297

Query: 728  QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 787
            + + A+   L ++  + +M+A +E    K + EL +QQ+E+   Q++  R + ++E++A+
Sbjct: 2298 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2355

Query: 788  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
            +  EE    QR  E    RQR+ E   + E    R+ E  R +    +  +  RKQ EE 
Sbjct: 2356 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2413

Query: 848  AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
             +     E A +        LE  R + + +A RLR    E +R++ ++Q++ +L++ + 
Sbjct: 2414 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2473

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            ++ + +++ Q  Q+ Q L Q  L    +  Q+        Q    L ++ + E  + +QL
Sbjct: 2474 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2530

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQ+RQQ             QQ +      V+      +   E ++   R+ ++ QQ +
Sbjct: 2531 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577

Query: 1021 QQHQQ 1025
            QQ +Q
Sbjct: 2578 QQRRQ 2582



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 771
            E++ Q +    A+ E+++ EAE  A+R    EE+  RQ EL  Q+ E  R+         
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708

Query: 772  ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 802
               +QE  R R E           EEELAR ++E A   Q+ QE               +
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1768

Query: 803  ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 828
            A + + EEE R   E++ +RLE                                   R+R
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1828

Query: 829  EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 876
             E ER   E+L        L+ + E A K    E E  RRL E+    R R+EE+AA+ +
Sbjct: 1829 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888

Query: 877  HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 925
             + EE     RK  + E++RQK L    +RQR+Q +E +  L+   ++     A+++L  
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1948

Query: 926  SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
                    +T   + QA L  A  ++L  E ER+ RE + R Q+ L  A ++  +Q++  
Sbjct: 1949 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2007

Query: 986  LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1025
            L     +       + L E  +QE ARQ+Q  Q+  Q+  Q
Sbjct: 2008 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2048



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)

Query: 607  QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            Q+RL  +QEL  L  + +  + Q+ L++++ A++   Q++AA ++Q++Q+L     + + 
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1757

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725
             K+R   + ++ S  R+     + S       + Q    E G   +L         A E 
Sbjct: 1758 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1803

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 782
             +    A+ AK +++  E +   +R E ER   E+L    E    + + E   + K  E 
Sbjct: 1804 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1863

Query: 783  EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 829
            E L R  ++EA +R+R +E A + + + EER  Q     +  L R        L +RR+ 
Sbjct: 1864 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1923

Query: 830  EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 859
            EEE                         R   E+ LR +E+   + AR+     EEE +R
Sbjct: 1924 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1983

Query: 860  RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 906
            R  E R    L  EEEAAR R    EE ER + ++E  R      ++E  RQ Q  QEA 
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2043

Query: 907  -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957
             +RLQ +        QQ++Q  Q  L    +   Q    A  ++     AE  +++ ERE
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2103

Query: 958  RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
                  Q R+Q E  + L+Q  ++Q Q           +   K   E +QE AR+ Q +Q
Sbjct: 2104 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2154

Query: 1018 QQQQQHQ 1024
               +Q Q
Sbjct: 2155 AALRQKQ 2161



 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 777
            E+L++L + +A    Q RR  E  A+ + +  +R  +LR+  +  L RQ+        +R
Sbjct: 1864 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1920

Query: 778  KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 830
            ++ EEE LA +   E+A   + E E+ L R R   E       Q + EA R+ +    EE
Sbjct: 1921 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1980

Query: 831  EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 880
              RR+ EE ++K    EEEAA+  +    E E  + ++EE R    R E+E+AR     +
Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
            E  +K L+ + +      +Q++QE  + LQQ+Q      + +  ++    +++     Q+
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2100

Query: 941  QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
            +   + +  Q  E ER +Q  EEQ + + +   A ++ +++ +Q+ +      + +   K
Sbjct: 2101 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2160

Query: 1001 SLLEIQQEEARQMQKQQQQQQ 1021
               + + E+ ++  +Q  +Q+
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQK 2181



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)

Query: 723  LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 771
            +E+ +Q++ A     ++A+ E + + A    K  + ER  QEE      LR + E   ++
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616

Query: 772  QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 826
            Q E ER R E E    R   K  EALR R + +E+A ++   + E  +Q+EEA R    R
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1676

Query: 827  RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 878
             + EE+  +Q EL           A +E E QR+L E     RL  E+E  RLR E    
Sbjct: 1677 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1725

Query: 879  EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 937
            E++R+  E E+ R Q+E     Q++QE    L + + + ++    L S +   ++S +T+
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1782

Query: 938  CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 989
             +S+  L       ++L EE  R R L EE +RQ++   +   +Q+ + +    +KL+  
Sbjct: 1783 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1842

Query: 990  GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
            G  ++                + L  + ++EA Q ++ ++Q  QH+
Sbjct: 1843 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)

Query: 604  ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
            E + ERL R  E  A +Q + L+ Q    +    + LAQ +KA+  S+ ++Q  L+    
Sbjct: 1860 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1915

Query: 664  QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 723
             TL+ R   +  I ++  S      G   EL+         E G +     DT       
Sbjct: 1916 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1965

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 765
            E     ++  AA+ E+ RREAE R ++    EEE  RQ               EE RR +
Sbjct: 1966 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2025

Query: 766  EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
            E         L+  QE  +KR + EE    K      +Q+EQE+        ++  QQE+
Sbjct: 2026 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2073

Query: 819  ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
            ++  L++ R E E  R+  E     E E A+   E E AQ R      R  EEA RL+  
Sbjct: 2074 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2120

Query: 879  EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 935
             EE+ +   + Q   E +R ++ +QEA RR Q +Q   +Q+Q A  ++     + +Q+  
Sbjct: 2121 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2179

Query: 936  TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
               Q +  L+   +Q  E + ++ L +E+ +R + E  +A +Q+ Q +++  S
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)

Query: 612  RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 669
            RQ++L A  + +  + ++  +Q+  A  +  A+Q+KAAL  ++ ++L   +++ + L+ R
Sbjct: 1971 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2027

Query: 670  ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 721
               ++         +  + +   +    + +Q      Q T+ +  SV D        G 
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2082

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 773
            A    +  E+A+ A+++ ER  A+ R + EE ER +Q    + Q         E LR++ 
Sbjct: 2083 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142

Query: 774  EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 815
            E+E  RR + E A  +Q++A                  + Q EQE+  LR Q EE + Q+
Sbjct: 2143 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2202

Query: 816  Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 857
               +E L+RL+    E   +R Q  EEL  +R Q EE +K              R+++  
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262

Query: 858  QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 891
            QR L+E   +M++             EAARLR   EE             K K   VQ  
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322

Query: 892  -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 943
                 + EL++Q+++  QE  RRLQ+ ++Q  QQLA+       T G Q    A + +  
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2376

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
               AE ++L + R  ++   Q R + +  +  ++Q ++  +KL      ++   T    L
Sbjct: 2377 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2434

Query: 1004 EIQQEEA 1010
            EIQ++++
Sbjct: 2435 EIQRQQS 2441



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)

Query: 725  QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            ++ ++ +A+A   E  +R      E+  K    E   QE++   Q   ++RQQ +    R
Sbjct: 2388 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2447

Query: 781  EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 827
              E +A  ++E+   +Q  + + L+ +     ++E+  Q+ +AL++         L+  R
Sbjct: 2448 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2507

Query: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 884
              E+E+ K E+L + +  +A +   E++  Q+++E+ R R+    EEA R +HE EE  R
Sbjct: 2508 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2567

Query: 885  KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
            ++ E  +Q E   Q+++QQE L   + Q+ ++QL  ++    +        TA Q  AT 
Sbjct: 2568 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2624

Query: 945  SL 946
            +L
Sbjct: 2625 TL 2626



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)

Query: 607  QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 666
            +  L +QQ+  A  Q + LQ  +  + QQ A+     Q+  L +++Q+QL +  +  + L
Sbjct: 2328 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2385

Query: 667  KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            K+R+++ +   +     +        + G        A+Q  V     V  L +      
Sbjct: 2386 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2442

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
               E+L++       + E+ ++EA++   + EE +  Q+E   Q+ + L++    E+   
Sbjct: 2443 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2502

Query: 781  EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 832
             + E    +++  L +  + E+A  +Q REE++RQQQ+    R      +EE RR + E 
Sbjct: 2503 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2562

Query: 833  ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
                RRKQEEL + +++   +     EE QR  E+ +L  E+  A L H EE
Sbjct: 2563 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2614



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
            +L Q ++  + + AKLEQ  ++   +A++  EE++RQ++   Q+ + L    EE R+R+ 
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560

Query: 782  E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            E EE  RRKQEE              Q+ E++R+QQEE L         EE +R +E+L 
Sbjct: 2561 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2599

Query: 841  RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 893
              +E+  A  A  EE       A + L   R  ++  AA    E   +  R+++  QR +
Sbjct: 2600 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2659

Query: 894  E 894
            E
Sbjct: 2660 E 2660



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)

Query: 850  WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 903
            W  E+EE +   +      N    +E  + L  E E +++K  E+Q   + L+R+    +
Sbjct: 631  WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 690

Query: 904  EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 961
              +   Q   Q Q    ++L        + N    Q  + +  AE  +QKL+E   R+  
Sbjct: 691  PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 750

Query: 962  EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             ++      L   LQ  Q +++Q     G++S  +   K++++++
Sbjct: 751  CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 795


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score =  114 bits (286), Expect = 5e-25
 Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 778
            ALE+ +QL +A A    Q  REA+   +R +EE  R+EE     +QQ+  ++ + ++ R+
Sbjct: 1372 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1431

Query: 779  RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 812
              E E  A+ +Q EA  R R   E+EI                      ALR + EE E 
Sbjct: 1432 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1491

Query: 813  --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 869
              RQ QEEA  RL  + ++E +R++Q E+ L  + +  A+ ARE++ A + LEE RL+ E
Sbjct: 1492 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1550

Query: 870  EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 901
            E   RLR  E ER R+                            +LE   Q+E +   Q 
Sbjct: 1551 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1610

Query: 902  QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
            ++EA RR QQQ        + +++L + +L ++     +        Q +L+ AE +K +
Sbjct: 1611 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1670

Query: 954  EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
            EE ER+ R     EEQ  +QRE    L +Q+ ++Q++L+         GT +  L  +QE
Sbjct: 1671 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1718

Query: 1009 EARQMQKQQQQQQQHQ 1024
              R   + +Q +QQ Q
Sbjct: 1719 LIRLRAETEQGEQQRQ 1734



 Score =  110 bits (275), Expect = 9e-24
 Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
            ++LQQ  + + + L+Q R EAE   +  EE  + + +  R+  +  R+ +E ER ++  E
Sbjct: 2067 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2126

Query: 784  ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
            E A+ + +     E LR++ EQE A R Q E+   +Q++ A   +E+ ++  E+  +Q+ 
Sbjct: 2127 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2186

Query: 839  LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
             + +QE    +   EE + Q+ L      ++EE  RL+ E  E  R+  +V  ++EL   
Sbjct: 2187 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2237

Query: 899  RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 956
            R Q +E L +L+ + + +  A +     +T            Q     A +    +E  R
Sbjct: 2238 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2296

Query: 957  ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
             RQL EE   QQR L + + +++ Q  Q+ +    +   +   +   E+ QE+AR++Q+ 
Sbjct: 2297 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2353

Query: 1017 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1068
            ++Q  Q         Q+   A       +                    A +        
Sbjct: 2354 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2413

Query: 1069 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1122
            A+     +   + A +E      T + +   S      L +++    R+ +K+++E KLL
Sbjct: 2414 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2473

Query: 1123 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1182
            +L     K+++  T   EQ+L               SFL E +S  +   +I     + +
Sbjct: 2474 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2518

Query: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1242
            + ++  +  + +  + +  QQRQQQQ+ Q++Q+        + +Q ++  G+       +
Sbjct: 2519 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2577

Query: 1243 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1270
             Q  Q   QQ    A ++ + +++ +++
Sbjct: 2578 QQLEQQRRQQEELLAEENQRLREQLQLL 2605



 Score =  103 bits (256), Expect = 1e-21
 Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)

Query: 759  EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 816
            E LRR +EE  +  +Q+ EER+R  E E A  KQ +      + +    R+ +E +++ Q
Sbjct: 1343 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1402

Query: 817  EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 871
            EE +RR E     ++++R  QEEL  LR+  E E    AR+ E A+R    +RLR+EEE 
Sbjct: 1403 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1458

Query: 872  -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 922
               RL+ E  ER+R   E E+Q    R +E   Q++Q QE   RL  Q Q + Q+  Q +
Sbjct: 1459 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1518

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
            +  +S    ++     + +A  +L E++   EE ER+LR+ +  + R++  AL+  Q+  
Sbjct: 1519 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1578

Query: 983  QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1037
            + +L         K +   +SL E     A+  ++ +++ QQ  +  RAR      L
Sbjct: 1579 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1635



 Score =  101 bits (251), Expect = 5e-21
 Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)

Query: 606  DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 662
            ++ERL  QQ   E   L +++    +Q  + + +AQ  AQ ++ A   QQ+ Q  ++ ++
Sbjct: 1350 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1409

Query: 663  FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 714
                +  +  Q    S+   +      S  E+Q  A Q    E           V  L L
Sbjct: 1410 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1465

Query: 715  DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 762
            + T    G A  +LQ L +A+A + E ++R+A+  A+R      +E +RKRQ E+     
Sbjct: 1466 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1524

Query: 763  -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 817
             + + E  R +Q      E  R + EE  RR ++  + R R+ ++AL   +   E + Q 
Sbjct: 1525 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1584

Query: 818  EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 871
            +     E+  + E   +++   + +  EEA + A+++ EA+R  EE    +E       E
Sbjct: 1585 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1644

Query: 872  AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 928
            A RLR + EE  +++   Q + E  ++ + ++EA RR + ++Q   Q++LA+ +L     
Sbjct: 1645 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1703

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
              + +      ++  L     +  + E++RQL EE+  R QRE   A Q++Q+ + +   
Sbjct: 1704 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1760

Query: 988  GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1020
                ++K     + LL  +   +EE+R   ++ +Q+
Sbjct: 1761 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1792



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)

Query: 613  QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 667
            +QELT L  Q++   +Q+ L+ ++  ++ A+  +AA    Q ++    + + +++   LK
Sbjct: 2189 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2248

Query: 668  MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 727
             RI  +N      R++ + D  +        ++           L +        L QL 
Sbjct: 2249 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2301

Query: 728  QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 787
            + + A+   L ++  + +M+A +E    K + EL +QQ+E+   Q++  R + ++E++A+
Sbjct: 2302 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2359

Query: 788  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
            +  EE    QR  E    RQR+ E   + E    R+ E  R +    +  +  RKQ EE 
Sbjct: 2360 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2417

Query: 848  AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
             +     E A +        LE  R + + +A RLR    E +R++ ++Q++ +L++ + 
Sbjct: 2418 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2477

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            ++ + +++ Q  Q+ Q L Q  L    +  Q+        Q    L ++ + E  + +QL
Sbjct: 2478 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2534

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQ+RQQ             QQ +      V+      +   E ++   R+ ++ QQ +
Sbjct: 2535 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2581

Query: 1021 QQHQQ 1025
            QQ +Q
Sbjct: 2582 QQRRQ 2586



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 771
            E++ Q +    A+ E+++ EAE  A+R    EE+  RQ EL  Q+ E  R+         
Sbjct: 1653 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1712

Query: 772  ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 802
               +QE  R R E           EEELAR ++E A   Q+ QE               +
Sbjct: 1713 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1772

Query: 803  ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 828
            A + + EEE R   E++ +RLE                                   R+R
Sbjct: 1773 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1832

Query: 829  EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 876
             E ER   E+L        L+ + E A K    E E  RRL E+    R R+EE+AA+ +
Sbjct: 1833 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1892

Query: 877  HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 925
             + EE     RK  + E++RQK L    +RQR+Q +E +  L+   ++     A+++L  
Sbjct: 1893 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1952

Query: 926  SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
                    +T   + QA L  A  ++L  E ER+ RE + R Q+ L  A ++  +Q++  
Sbjct: 1953 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2011

Query: 986  LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1025
            L     +       + L E  +QE ARQ+Q  Q+  Q+  Q
Sbjct: 2012 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2052



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)

Query: 607  QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            Q+RL  +QEL  L  + +  + Q+ L++++ A++   Q++AA ++Q++Q+L     + + 
Sbjct: 1710 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1761

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725
             K+R   + ++ S  R+     + S       + Q    E G   +L         A E 
Sbjct: 1762 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1807

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 782
             +    A+ AK +++  E +   +R E ER   E+L    E    + + E   + K  E 
Sbjct: 1808 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1867

Query: 783  EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 829
            E L R  ++EA +R+R +E A + + + EER  Q     +  L R        L +RR+ 
Sbjct: 1868 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1927

Query: 830  EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 859
            EEE                         R   E+ LR +E+   + AR+     EEE +R
Sbjct: 1928 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1987

Query: 860  RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 906
            R  E R    L  EEEAAR R    EE ER + ++E  R      ++E  RQ Q  QEA 
Sbjct: 1988 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2047

Query: 907  -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957
             +RLQ +        QQ++Q  Q  L    +   Q    A  ++     AE  +++ ERE
Sbjct: 2048 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2107

Query: 958  RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
                  Q R+Q E  + L+Q  ++Q Q           +   K   E +QE AR+ Q +Q
Sbjct: 2108 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2158

Query: 1018 QQQQQHQ 1024
               +Q Q
Sbjct: 2159 AALRQKQ 2165



 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 777
            E+L++L + +A    Q RR  E  A+ + +  +R  +LR+  +  L RQ+        +R
Sbjct: 1868 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1924

Query: 778  KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 830
            ++ EEE LA +   E+A   + E E+ L R R   E       Q + EA R+ +    EE
Sbjct: 1925 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1984

Query: 831  EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 880
              RR+ EE ++K    EEEAA+  +    E E  + ++EE R    R E+E+AR     +
Sbjct: 1985 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2044

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
            E  +K L+ + +      +Q++QE  + LQQ+Q      + +  ++    +++     Q+
Sbjct: 2045 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2104

Query: 941  QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
            +   + +  Q  E ER +Q  EEQ + + +   A ++ +++ +Q+ +      + +   K
Sbjct: 2105 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2164

Query: 1001 SLLEIQQEEARQMQKQQQQQQ 1021
               + + E+ ++  +Q  +Q+
Sbjct: 2165 QAADAEMEKHKKFAEQTLRQK 2185



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)

Query: 723  LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 771
            +E+ +Q++ A     ++A+ E + + A    K  + ER  QEE      LR + E   ++
Sbjct: 1561 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1620

Query: 772  QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 826
            Q E ER R E E    R   K  EALR R + +E+A ++   + E  +Q+EEA R    R
Sbjct: 1621 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1680

Query: 827  RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 878
             + EE+  +Q EL           A +E E QR+L E     RL  E+E  RLR E    
Sbjct: 1681 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1729

Query: 879  EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 937
            E++R+  E E+ R Q+E     Q++QE    L + + + ++    L S +   ++S +T+
Sbjct: 1730 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1786

Query: 938  CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 989
             +S+  L       ++L EE  R R L EE +RQ++   +   +Q+ + +    +KL+  
Sbjct: 1787 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1846

Query: 990  GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
            G  ++                + L  + ++EA Q ++ ++Q  QH+
Sbjct: 1847 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1892



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)

Query: 604  ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
            E + ERL R  E  A +Q + L+ Q    +    + LAQ +KA+  S+ ++Q  L+    
Sbjct: 1864 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1919

Query: 664  QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 723
             TL+ R   +  I ++  S      G   EL+         E G +     DT       
Sbjct: 1920 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1969

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 765
            E     ++  AA+ E+ RREAE R ++    EEE  RQ               EE RR +
Sbjct: 1970 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2029

Query: 766  EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
            E         L+  QE  +KR + EE    K      +Q+EQE+        ++  QQE+
Sbjct: 2030 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2077

Query: 819  ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
            ++  L++ R E E  R+  E     E E A+   E E AQ R      R  EEA RL+  
Sbjct: 2078 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2124

Query: 879  EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 935
             EE+ +   + Q   E +R ++ +QEA RR Q +Q   +Q+Q A  ++     + +Q+  
Sbjct: 2125 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2183

Query: 936  TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
               Q +  L+   +Q  E + ++ L +E+ +R + E  +A +Q+ Q +++  S
Sbjct: 2184 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2236



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)

Query: 612  RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 669
            RQ++L A  + +  + ++  +Q+  A  +  A+Q+KAAL  ++ ++L   +++ + L+ R
Sbjct: 1975 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2031

Query: 670  ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 721
               ++         +  + +   +    + +Q      Q T+ +  SV D        G 
Sbjct: 2032 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2086

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 773
            A    +  E+A+ A+++ ER  A+ R + EE ER +Q    + Q         E LR++ 
Sbjct: 2087 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2146

Query: 774  EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 815
            E+E  RR + E A  +Q++A                  + Q EQE+  LR Q EE + Q+
Sbjct: 2147 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2206

Query: 816  Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 857
               +E L+RL+    E   +R Q  EEL  +R Q EE +K              R+++  
Sbjct: 2207 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2266

Query: 858  QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 891
            QR L+E   +M++             EAARLR   EE             K K   VQ  
Sbjct: 2267 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2326

Query: 892  -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 943
                 + EL++Q+++  QE  RRLQ+ ++Q  QQLA+       T G Q    A + +  
Sbjct: 2327 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2380

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
               AE ++L + R  ++   Q R + +  +  ++Q ++  +KL      ++   T    L
Sbjct: 2381 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2438

Query: 1004 EIQQEEA 1010
            EIQ++++
Sbjct: 2439 EIQRQQS 2445



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)

Query: 725  QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            ++ ++ +A+A   E  +R      E+  K    E   QE++   Q   ++RQQ +    R
Sbjct: 2392 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2451

Query: 781  EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 827
              E +A  ++E+   +Q  + + L+ +     ++E+  Q+ +AL++         L+  R
Sbjct: 2452 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2511

Query: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 884
              E+E+ K E+L + +  +A +   E++  Q+++E+ R R+    EEA R +HE EE  R
Sbjct: 2512 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2571

Query: 885  KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
            ++ E  +Q E   Q+++QQE L   + Q+ ++QL  ++    +        TA Q  AT 
Sbjct: 2572 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2628

Query: 945  SL 946
            +L
Sbjct: 2629 TL 2630



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)

Query: 607  QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 666
            +  L +QQ+  A  Q + LQ  +  + QQ A+     Q+  L +++Q+QL +  +  + L
Sbjct: 2332 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2389

Query: 667  KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            K+R+++ +   +     +        + G        A+Q  V     V  L +      
Sbjct: 2390 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2446

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
               E+L++       + E+ ++EA++   + EE +  Q+E   Q+ + L++    E+   
Sbjct: 2447 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2506

Query: 781  EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 832
             + E    +++  L +  + E+A  +Q REE++RQQQ+    R      +EE RR + E 
Sbjct: 2507 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2566

Query: 833  ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
                RRKQEEL + +++   +     EE QR  E+ +L  E+  A L H EE
Sbjct: 2567 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2618



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
            +L Q ++  + + AKLEQ  ++   +A++  EE++RQ++   Q+ + L    EE R+R+ 
Sbjct: 2505 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2564

Query: 782  E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            E EE  RRKQEE              Q+ E++R+QQEE L         EE +R +E+L 
Sbjct: 2565 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2603

Query: 841  RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 893
              +E+  A  A  EE       A + L   R  ++  AA    E   +  R+++  QR +
Sbjct: 2604 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2663

Query: 894  E 894
            E
Sbjct: 2664 E 2664



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)

Query: 850  WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 903
            W  E+EE +   +      N    +E  + L  E E +++K  E+Q   + L+R+    +
Sbjct: 635  WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 694

Query: 904  EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 961
              +   Q   Q Q    ++L        + N    Q  + +  AE  +QKL+E   R+  
Sbjct: 695  PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 754

Query: 962  EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             ++      L   LQ  Q +++Q     G++S  +   K++++++
Sbjct: 755  CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 799


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score =  114 bits (286), Expect = 5e-25
 Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 778
            ALE+ +QL +A A    Q  REA+   +R +EE  R+EE     +QQ+  ++ + ++ R+
Sbjct: 1368 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1427

Query: 779  RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 812
              E E  A+ +Q EA  R R   E+EI                      ALR + EE E 
Sbjct: 1428 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1487

Query: 813  --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 869
              RQ QEEA  RL  + ++E +R++Q E+ L  + +  A+ ARE++ A + LEE RL+ E
Sbjct: 1488 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1546

Query: 870  EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 901
            E   RLR  E ER R+                            +LE   Q+E +   Q 
Sbjct: 1547 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1606

Query: 902  QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
            ++EA RR QQQ        + +++L + +L ++     +        Q +L+ AE +K +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666

Query: 954  EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
            EE ER+ R     EEQ  +QRE    L +Q+ ++Q++L+         GT +  L  +QE
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1714

Query: 1009 EARQMQKQQQQQQQHQ 1024
              R   + +Q +QQ Q
Sbjct: 1715 LIRLRAETEQGEQQRQ 1730



 Score =  110 bits (275), Expect = 9e-24
 Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
            ++LQQ  + + + L+Q R EAE   +  EE  + + +  R+  +  R+ +E ER ++  E
Sbjct: 2063 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2122

Query: 784  ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
            E A+ + +     E LR++ EQE A R Q E+   +Q++ A   +E+ ++  E+  +Q+ 
Sbjct: 2123 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2182

Query: 839  LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
             + +QE    +   EE + Q+ L      ++EE  RL+ E  E  R+  +V  ++EL   
Sbjct: 2183 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2233

Query: 899  RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 956
            R Q +E L +L+ + + +  A +     +T            Q     A +    +E  R
Sbjct: 2234 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292

Query: 957  ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
             RQL EE   QQR L + + +++ Q  Q+ +    +   +   +   E+ QE+AR++Q+ 
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2349

Query: 1017 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1068
            ++Q  Q         Q+   A       +                    A +        
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409

Query: 1069 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1122
            A+     +   + A +E      T + +   S      L +++    R+ +K+++E KLL
Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469

Query: 1123 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1182
            +L     K+++  T   EQ+L               SFL E +S  +   +I     + +
Sbjct: 2470 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2514

Query: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1242
            + ++  +  + +  + +  QQRQQQQ+ Q++Q+        + +Q ++  G+       +
Sbjct: 2515 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2573

Query: 1243 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1270
             Q  Q   QQ    A ++ + +++ +++
Sbjct: 2574 QQLEQQRRQQEELLAEENQRLREQLQLL 2601



 Score =  103 bits (256), Expect = 1e-21
 Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)

Query: 759  EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 816
            E LRR +EE  +  +Q+ EER+R  E E A  KQ +      + +    R+ +E +++ Q
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398

Query: 817  EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 871
            EE +RR E     ++++R  QEEL  LR+  E E    AR+ E A+R    +RLR+EEE 
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1454

Query: 872  -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 922
               RL+ E  ER+R   E E+Q    R +E   Q++Q QE   RL  Q Q + Q+  Q +
Sbjct: 1455 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1514

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
            +  +S    ++     + +A  +L E++   EE ER+LR+ +  + R++  AL+  Q+  
Sbjct: 1515 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1574

Query: 983  QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1037
            + +L         K +   +SL E     A+  ++ +++ QQ  +  RAR      L
Sbjct: 1575 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1631



 Score =  101 bits (251), Expect = 5e-21
 Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)

Query: 606  DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 662
            ++ERL  QQ   E   L +++    +Q  + + +AQ  AQ ++ A   QQ+ Q  ++ ++
Sbjct: 1346 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1405

Query: 663  FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 714
                +  +  Q    S+   +      S  E+Q  A Q    E           V  L L
Sbjct: 1406 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1461

Query: 715  DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 762
            + T    G A  +LQ L +A+A + E ++R+A+  A+R      +E +RKRQ E+     
Sbjct: 1462 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1520

Query: 763  -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 817
             + + E  R +Q      E  R + EE  RR ++  + R R+ ++AL   +   E + Q 
Sbjct: 1521 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1580

Query: 818  EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 871
            +     E+  + E   +++   + +  EEA + A+++ EA+R  EE    +E       E
Sbjct: 1581 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1640

Query: 872  AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 928
            A RLR + EE  +++   Q + E  ++ + ++EA RR + ++Q   Q++LA+ +L     
Sbjct: 1641 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1699

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
              + +      ++  L     +  + E++RQL EE+  R QRE   A Q++Q+ + +   
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1756

Query: 988  GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1020
                ++K     + LL  +   +EE+R   ++ +Q+
Sbjct: 1757 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1788



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)

Query: 613  QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 667
            +QELT L  Q++   +Q+ L+ ++  ++ A+  +AA    Q ++    + + +++   LK
Sbjct: 2185 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2244

Query: 668  MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 727
             RI  +N      R++ + D  +        ++           L +        L QL 
Sbjct: 2245 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2297

Query: 728  QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 787
            + + A+   L ++  + +M+A +E    K + EL +QQ+E+   Q++  R + ++E++A+
Sbjct: 2298 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2355

Query: 788  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
            +  EE    QR  E    RQR+ E   + E    R+ E  R +    +  +  RKQ EE 
Sbjct: 2356 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2413

Query: 848  AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
             +     E A +        LE  R + + +A RLR    E +R++ ++Q++ +L++ + 
Sbjct: 2414 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2473

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            ++ + +++ Q  Q+ Q L Q  L    +  Q+        Q    L ++ + E  + +QL
Sbjct: 2474 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2530

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQ+RQQ             QQ +      V+      +   E ++   R+ ++ QQ +
Sbjct: 2531 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577

Query: 1021 QQHQQ 1025
            QQ +Q
Sbjct: 2578 QQRRQ 2582



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 771
            E++ Q +    A+ E+++ EAE  A+R    EE+  RQ EL  Q+ E  R+         
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708

Query: 772  ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 802
               +QE  R R E           EEELAR ++E A   Q+ QE               +
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1768

Query: 803  ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 828
            A + + EEE R   E++ +RLE                                   R+R
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1828

Query: 829  EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 876
             E ER   E+L        L+ + E A K    E E  RRL E+    R R+EE+AA+ +
Sbjct: 1829 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888

Query: 877  HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 925
             + EE     RK  + E++RQK L    +RQR+Q +E +  L+   ++     A+++L  
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1948

Query: 926  SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
                    +T   + QA L  A  ++L  E ER+ RE + R Q+ L  A ++  +Q++  
Sbjct: 1949 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2007

Query: 986  LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1025
            L     +       + L E  +QE ARQ+Q  Q+  Q+  Q
Sbjct: 2008 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2048



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)

Query: 607  QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            Q+RL  +QEL  L  + +  + Q+ L++++ A++   Q++AA ++Q++Q+L     + + 
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1757

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725
             K+R   + ++ S  R+     + S       + Q    E G   +L         A E 
Sbjct: 1758 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1803

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 782
             +    A+ AK +++  E +   +R E ER   E+L    E    + + E   + K  E 
Sbjct: 1804 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1863

Query: 783  EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 829
            E L R  ++EA +R+R +E A + + + EER  Q     +  L R        L +RR+ 
Sbjct: 1864 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1923

Query: 830  EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 859
            EEE                         R   E+ LR +E+   + AR+     EEE +R
Sbjct: 1924 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1983

Query: 860  RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 906
            R  E R    L  EEEAAR R    EE ER + ++E  R      ++E  RQ Q  QEA 
Sbjct: 1984 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2043

Query: 907  -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957
             +RLQ +        QQ++Q  Q  L    +   Q    A  ++     AE  +++ ERE
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2103

Query: 958  RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
                  Q R+Q E  + L+Q  ++Q Q           +   K   E +QE AR+ Q +Q
Sbjct: 2104 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2154

Query: 1018 QQQQQHQ 1024
               +Q Q
Sbjct: 2155 AALRQKQ 2161



 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 777
            E+L++L + +A    Q RR  E  A+ + +  +R  +LR+  +  L RQ+        +R
Sbjct: 1864 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1920

Query: 778  KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 830
            ++ EEE LA +   E+A   + E E+ L R R   E       Q + EA R+ +    EE
Sbjct: 1921 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1980

Query: 831  EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 880
              RR+ EE ++K    EEEAA+  +    E E  + ++EE R    R E+E+AR     +
Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2040

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
            E  +K L+ + +      +Q++QE  + LQQ+Q      + +  ++    +++     Q+
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2100

Query: 941  QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
            +   + +  Q  E ER +Q  EEQ + + +   A ++ +++ +Q+ +      + +   K
Sbjct: 2101 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2160

Query: 1001 SLLEIQQEEARQMQKQQQQQQ 1021
               + + E+ ++  +Q  +Q+
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQK 2181



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)

Query: 723  LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 771
            +E+ +Q++ A     ++A+ E + + A    K  + ER  QEE      LR + E   ++
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616

Query: 772  QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 826
            Q E ER R E E    R   K  EALR R + +E+A ++   + E  +Q+EEA R    R
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1676

Query: 827  RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 878
             + EE+  +Q EL           A +E E QR+L E     RL  E+E  RLR E    
Sbjct: 1677 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1725

Query: 879  EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 937
            E++R+  E E+ R Q+E     Q++QE    L + + + ++    L S +   ++S +T+
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1782

Query: 938  CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 989
             +S+  L       ++L EE  R R L EE +RQ++   +   +Q+ + +    +KL+  
Sbjct: 1783 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1842

Query: 990  GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
            G  ++                + L  + ++EA Q ++ ++Q  QH+
Sbjct: 1843 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)

Query: 604  ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
            E + ERL R  E  A +Q + L+ Q    +    + LAQ +KA+  S+ ++Q  L+    
Sbjct: 1860 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1915

Query: 664  QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 723
             TL+ R   +  I ++  S      G   EL+         E G +     DT       
Sbjct: 1916 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1965

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 765
            E     ++  AA+ E+ RREAE R ++    EEE  RQ               EE RR +
Sbjct: 1966 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2025

Query: 766  EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
            E         L+  QE  +KR + EE    K      +Q+EQE+        ++  QQE+
Sbjct: 2026 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2073

Query: 819  ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
            ++  L++ R E E  R+  E     E E A+   E E AQ R      R  EEA RL+  
Sbjct: 2074 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2120

Query: 879  EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 935
             EE+ +   + Q   E +R ++ +QEA RR Q +Q   +Q+Q A  ++     + +Q+  
Sbjct: 2121 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2179

Query: 936  TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
               Q +  L+   +Q  E + ++ L +E+ +R + E  +A +Q+ Q +++  S
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)

Query: 612  RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 669
            RQ++L A  + +  + ++  +Q+  A  +  A+Q+KAAL  ++ ++L   +++ + L+ R
Sbjct: 1971 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2027

Query: 670  ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 721
               ++         +  + +   +    + +Q      Q T+ +  SV D        G 
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2082

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 773
            A    +  E+A+ A+++ ER  A+ R + EE ER +Q    + Q         E LR++ 
Sbjct: 2083 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142

Query: 774  EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 815
            E+E  RR + E A  +Q++A                  + Q EQE+  LR Q EE + Q+
Sbjct: 2143 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2202

Query: 816  Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 857
               +E L+RL+    E   +R Q  EEL  +R Q EE +K              R+++  
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262

Query: 858  QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 891
            QR L+E   +M++             EAARLR   EE             K K   VQ  
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322

Query: 892  -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 943
                 + EL++Q+++  QE  RRLQ+ ++Q  QQLA+       T G Q    A + +  
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2376

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
               AE ++L + R  ++   Q R + +  +  ++Q ++  +KL      ++   T    L
Sbjct: 2377 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2434

Query: 1004 EIQQEEA 1010
            EIQ++++
Sbjct: 2435 EIQRQQS 2441



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)

Query: 725  QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            ++ ++ +A+A   E  +R      E+  K    E   QE++   Q   ++RQQ +    R
Sbjct: 2388 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2447

Query: 781  EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 827
              E +A  ++E+   +Q  + + L+ +     ++E+  Q+ +AL++         L+  R
Sbjct: 2448 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2507

Query: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 884
              E+E+ K E+L + +  +A +   E++  Q+++E+ R R+    EEA R +HE EE  R
Sbjct: 2508 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2567

Query: 885  KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
            ++ E  +Q E   Q+++QQE L   + Q+ ++QL  ++    +        TA Q  AT 
Sbjct: 2568 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2624

Query: 945  SL 946
            +L
Sbjct: 2625 TL 2626



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)

Query: 607  QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 666
            +  L +QQ+  A  Q + LQ  +  + QQ A+     Q+  L +++Q+QL +  +  + L
Sbjct: 2328 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2385

Query: 667  KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            K+R+++ +   +     +        + G        A+Q  V     V  L +      
Sbjct: 2386 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2442

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
               E+L++       + E+ ++EA++   + EE +  Q+E   Q+ + L++    E+   
Sbjct: 2443 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2502

Query: 781  EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 832
             + E    +++  L +  + E+A  +Q REE++RQQQ+    R      +EE RR + E 
Sbjct: 2503 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2562

Query: 833  ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
                RRKQEEL + +++   +     EE QR  E+ +L  E+  A L H EE
Sbjct: 2563 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2614



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
            +L Q ++  + + AKLEQ  ++   +A++  EE++RQ++   Q+ + L    EE R+R+ 
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560

Query: 782  E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            E EE  RRKQEE              Q+ E++R+QQEE L         EE +R +E+L 
Sbjct: 2561 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2599

Query: 841  RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 893
              +E+  A  A  EE       A + L   R  ++  AA    E   +  R+++  QR +
Sbjct: 2600 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2659

Query: 894  E 894
            E
Sbjct: 2660 E 2660



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)

Query: 850  WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 903
            W  E+EE +   +      N    +E  + L  E E +++K  E+Q   + L+R+    +
Sbjct: 631  WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 690

Query: 904  EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 961
              +   Q   Q Q    ++L        + N    Q  + +  AE  +QKL+E   R+  
Sbjct: 691  PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 750

Query: 962  EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             ++      L   LQ  Q +++Q     G++S  +   K++++++
Sbjct: 751  CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 795


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score =  114 bits (286), Expect = 5e-25
 Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 778
            ALE+ +QL +A A    Q  REA+   +R +EE  R+EE     +QQ+  ++ + ++ R+
Sbjct: 1336 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1395

Query: 779  RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 812
              E E  A+ +Q EA  R R   E+EI                      ALR + EE E 
Sbjct: 1396 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1455

Query: 813  --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 869
              RQ QEEA  RL  + ++E +R++Q E+ L  + +  A+ ARE++ A + LEE RL+ E
Sbjct: 1456 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1514

Query: 870  EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 901
            E   RLR  E ER R+                            +LE   Q+E +   Q 
Sbjct: 1515 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1574

Query: 902  QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
            ++EA RR QQQ        + +++L + +L ++     +        Q +L+ AE +K +
Sbjct: 1575 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1634

Query: 954  EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
            EE ER+ R     EEQ  +QRE    L +Q+ ++Q++L+         GT +  L  +QE
Sbjct: 1635 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1682

Query: 1009 EARQMQKQQQQQQQHQ 1024
              R   + +Q +QQ Q
Sbjct: 1683 LIRLRAETEQGEQQRQ 1698



 Score =  110 bits (275), Expect = 9e-24
 Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
            ++LQQ  + + + L+Q R EAE   +  EE  + + +  R+  +  R+ +E ER ++  E
Sbjct: 2031 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2090

Query: 784  ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
            E A+ + +     E LR++ EQE A R Q E+   +Q++ A   +E+ ++  E+  +Q+ 
Sbjct: 2091 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2150

Query: 839  LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
             + +QE    +   EE + Q+ L      ++EE  RL+ E  E  R+  +V  ++EL   
Sbjct: 2151 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2201

Query: 899  RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 956
            R Q +E L +L+ + + +  A +     +T            Q     A +    +E  R
Sbjct: 2202 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2260

Query: 957  ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
             RQL EE   QQR L + + +++ Q  Q+ +    +   +   +   E+ QE+AR++Q+ 
Sbjct: 2261 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2317

Query: 1017 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1068
            ++Q  Q         Q+   A       +                    A +        
Sbjct: 2318 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2377

Query: 1069 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1122
            A+     +   + A +E      T + +   S      L +++    R+ +K+++E KLL
Sbjct: 2378 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2437

Query: 1123 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1182
            +L     K+++  T   EQ+L               SFL E +S  +   +I     + +
Sbjct: 2438 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2482

Query: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1242
            + ++  +  + +  + +  QQRQQQQ+ Q++Q+        + +Q ++  G+       +
Sbjct: 2483 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2541

Query: 1243 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1270
             Q  Q   QQ    A ++ + +++ +++
Sbjct: 2542 QQLEQQRRQQEELLAEENQRLREQLQLL 2569



 Score =  103 bits (256), Expect = 1e-21
 Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)

Query: 759  EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 816
            E LRR +EE  +  +Q+ EER+R  E E A  KQ +      + +    R+ +E +++ Q
Sbjct: 1307 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1366

Query: 817  EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 871
            EE +RR E     ++++R  QEEL  LR+  E E    AR+ E A+R    +RLR+EEE 
Sbjct: 1367 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1422

Query: 872  -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 922
               RL+ E  ER+R   E E+Q    R +E   Q++Q QE   RL  Q Q + Q+  Q +
Sbjct: 1423 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1482

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
            +  +S    ++     + +A  +L E++   EE ER+LR+ +  + R++  AL+  Q+  
Sbjct: 1483 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1542

Query: 983  QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1037
            + +L         K +   +SL E     A+  ++ +++ QQ  +  RAR      L
Sbjct: 1543 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1599



 Score =  101 bits (251), Expect = 5e-21
 Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)

Query: 606  DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 662
            ++ERL  QQ   E   L +++    +Q  + + +AQ  AQ ++ A   QQ+ Q  ++ ++
Sbjct: 1314 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1373

Query: 663  FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 714
                +  +  Q    S+   +      S  E+Q  A Q    E           V  L L
Sbjct: 1374 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1429

Query: 715  DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 762
            + T    G A  +LQ L +A+A + E ++R+A+  A+R      +E +RKRQ E+     
Sbjct: 1430 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1488

Query: 763  -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 817
             + + E  R +Q      E  R + EE  RR ++  + R R+ ++AL   +   E + Q 
Sbjct: 1489 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1548

Query: 818  EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 871
            +     E+  + E   +++   + +  EEA + A+++ EA+R  EE    +E       E
Sbjct: 1549 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1608

Query: 872  AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 928
            A RLR + EE  +++   Q + E  ++ + ++EA RR + ++Q   Q++LA+ +L     
Sbjct: 1609 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1667

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
              + +      ++  L     +  + E++RQL EE+  R QRE   A Q++Q+ + +   
Sbjct: 1668 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1724

Query: 988  GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1020
                ++K     + LL  +   +EE+R   ++ +Q+
Sbjct: 1725 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1756



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)

Query: 613  QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 667
            +QELT L  Q++   +Q+ L+ ++  ++ A+  +AA    Q ++    + + +++   LK
Sbjct: 2153 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2212

Query: 668  MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 727
             RI  +N      R++ + D  +        ++           L +        L QL 
Sbjct: 2213 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2265

Query: 728  QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 787
            + + A+   L ++  + +M+A +E    K + EL +QQ+E+   Q++  R + ++E++A+
Sbjct: 2266 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2323

Query: 788  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
            +  EE    QR  E    RQR+ E   + E    R+ E  R +    +  +  RKQ EE 
Sbjct: 2324 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2381

Query: 848  AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
             +     E A +        LE  R + + +A RLR    E +R++ ++Q++ +L++ + 
Sbjct: 2382 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2441

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            ++ + +++ Q  Q+ Q L Q  L    +  Q+        Q    L ++ + E  + +QL
Sbjct: 2442 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2498

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQ+RQQ             QQ +      V+      +   E ++   R+ ++ QQ +
Sbjct: 2499 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2545

Query: 1021 QQHQQ 1025
            QQ +Q
Sbjct: 2546 QQRRQ 2550



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 771
            E++ Q +    A+ E+++ EAE  A+R    EE+  RQ EL  Q+ E  R+         
Sbjct: 1617 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1676

Query: 772  ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 802
               +QE  R R E           EEELAR ++E A   Q+ QE               +
Sbjct: 1677 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1736

Query: 803  ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 828
            A + + EEE R   E++ +RLE                                   R+R
Sbjct: 1737 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1796

Query: 829  EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 876
             E ER   E+L        L+ + E A K    E E  RRL E+    R R+EE+AA+ +
Sbjct: 1797 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1856

Query: 877  HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 925
             + EE     RK  + E++RQK L    +RQR+Q +E +  L+   ++     A+++L  
Sbjct: 1857 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1916

Query: 926  SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
                    +T   + QA L  A  ++L  E ER+ RE + R Q+ L  A ++  +Q++  
Sbjct: 1917 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 1975

Query: 986  LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1025
            L     +       + L E  +QE ARQ+Q  Q+  Q+  Q
Sbjct: 1976 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2016



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)

Query: 607  QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            Q+RL  +QEL  L  + +  + Q+ L++++ A++   Q++AA ++Q++Q+L     + + 
Sbjct: 1674 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1725

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725
             K+R   + ++ S  R+     + S       + Q    E G   +L         A E 
Sbjct: 1726 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1771

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 782
             +    A+ AK +++  E +   +R E ER   E+L    E    + + E   + K  E 
Sbjct: 1772 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1831

Query: 783  EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 829
            E L R  ++EA +R+R +E A + + + EER  Q     +  L R        L +RR+ 
Sbjct: 1832 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1891

Query: 830  EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 859
            EEE                         R   E+ LR +E+   + AR+     EEE +R
Sbjct: 1892 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1951

Query: 860  RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 906
            R  E R    L  EEEAAR R    EE ER + ++E  R      ++E  RQ Q  QEA 
Sbjct: 1952 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2011

Query: 907  -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957
             +RLQ +        QQ++Q  Q  L    +   Q    A  ++     AE  +++ ERE
Sbjct: 2012 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2071

Query: 958  RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
                  Q R+Q E  + L+Q  ++Q Q           +   K   E +QE AR+ Q +Q
Sbjct: 2072 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2122

Query: 1018 QQQQQHQ 1024
               +Q Q
Sbjct: 2123 AALRQKQ 2129



 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 777
            E+L++L + +A    Q RR  E  A+ + +  +R  +LR+  +  L RQ+        +R
Sbjct: 1832 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1888

Query: 778  KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 830
            ++ EEE LA +   E+A   + E E+ L R R   E       Q + EA R+ +    EE
Sbjct: 1889 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1948

Query: 831  EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 880
              RR+ EE ++K    EEEAA+  +    E E  + ++EE R    R E+E+AR     +
Sbjct: 1949 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2008

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
            E  +K L+ + +      +Q++QE  + LQQ+Q      + +  ++    +++     Q+
Sbjct: 2009 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2068

Query: 941  QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
            +   + +  Q  E ER +Q  EEQ + + +   A ++ +++ +Q+ +      + +   K
Sbjct: 2069 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2128

Query: 1001 SLLEIQQEEARQMQKQQQQQQ 1021
               + + E+ ++  +Q  +Q+
Sbjct: 2129 QAADAEMEKHKKFAEQTLRQK 2149



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)

Query: 723  LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 771
            +E+ +Q++ A     ++A+ E + + A    K  + ER  QEE      LR + E   ++
Sbjct: 1525 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1584

Query: 772  QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 826
            Q E ER R E E    R   K  EALR R + +E+A ++   + E  +Q+EEA R    R
Sbjct: 1585 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1644

Query: 827  RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 878
             + EE+  +Q EL           A +E E QR+L E     RL  E+E  RLR E    
Sbjct: 1645 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1693

Query: 879  EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 937
            E++R+  E E+ R Q+E     Q++QE    L + + + ++    L S +   ++S +T+
Sbjct: 1694 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1750

Query: 938  CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 989
             +S+  L       ++L EE  R R L EE +RQ++   +   +Q+ + +    +KL+  
Sbjct: 1751 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1810

Query: 990  GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
            G  ++                + L  + ++EA Q ++ ++Q  QH+
Sbjct: 1811 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1856



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)

Query: 604  ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
            E + ERL R  E  A +Q + L+ Q    +    + LAQ +KA+  S+ ++Q  L+    
Sbjct: 1828 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1883

Query: 664  QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 723
             TL+ R   +  I ++  S      G   EL+         E G +     DT       
Sbjct: 1884 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1933

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 765
            E     ++  AA+ E+ RREAE R ++    EEE  RQ               EE RR +
Sbjct: 1934 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 1993

Query: 766  EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
            E         L+  QE  +KR + EE    K      +Q+EQE+        ++  QQE+
Sbjct: 1994 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2041

Query: 819  ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
            ++  L++ R E E  R+  E     E E A+   E E AQ R      R  EEA RL+  
Sbjct: 2042 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2088

Query: 879  EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 935
             EE+ +   + Q   E +R ++ +QEA RR Q +Q   +Q+Q A  ++     + +Q+  
Sbjct: 2089 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2147

Query: 936  TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
               Q +  L+   +Q  E + ++ L +E+ +R + E  +A +Q+ Q +++  S
Sbjct: 2148 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2200



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)

Query: 612  RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 669
            RQ++L A  + +  + ++  +Q+  A  +  A+Q+KAAL  ++ ++L   +++ + L+ R
Sbjct: 1939 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 1995

Query: 670  ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 721
               ++         +  + +   +    + +Q      Q T+ +  SV D        G 
Sbjct: 1996 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2050

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 773
            A    +  E+A+ A+++ ER  A+ R + EE ER +Q    + Q         E LR++ 
Sbjct: 2051 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2110

Query: 774  EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 815
            E+E  RR + E A  +Q++A                  + Q EQE+  LR Q EE + Q+
Sbjct: 2111 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2170

Query: 816  Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 857
               +E L+RL+    E   +R Q  EEL  +R Q EE +K              R+++  
Sbjct: 2171 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2230

Query: 858  QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 891
            QR L+E   +M++             EAARLR   EE             K K   VQ  
Sbjct: 2231 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2290

Query: 892  -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 943
                 + EL++Q+++  QE  RRLQ+ ++Q  QQLA+       T G Q    A + +  
Sbjct: 2291 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2344

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
               AE ++L + R  ++   Q R + +  +  ++Q ++  +KL      ++   T    L
Sbjct: 2345 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2402

Query: 1004 EIQQEEA 1010
            EIQ++++
Sbjct: 2403 EIQRQQS 2409



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)

Query: 725  QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            ++ ++ +A+A   E  +R      E+  K    E   QE++   Q   ++RQQ +    R
Sbjct: 2356 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2415

Query: 781  EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 827
              E +A  ++E+   +Q  + + L+ +     ++E+  Q+ +AL++         L+  R
Sbjct: 2416 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2475

Query: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 884
              E+E+ K E+L + +  +A +   E++  Q+++E+ R R+    EEA R +HE EE  R
Sbjct: 2476 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2535

Query: 885  KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
            ++ E  +Q E   Q+++QQE L   + Q+ ++QL  ++    +        TA Q  AT 
Sbjct: 2536 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2592

Query: 945  SL 946
            +L
Sbjct: 2593 TL 2594



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)

Query: 607  QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 666
            +  L +QQ+  A  Q + LQ  +  + QQ A+     Q+  L +++Q+QL +  +  + L
Sbjct: 2296 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2353

Query: 667  KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            K+R+++ +   +     +        + G        A+Q  V     V  L +      
Sbjct: 2354 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2410

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
               E+L++       + E+ ++EA++   + EE +  Q+E   Q+ + L++    E+   
Sbjct: 2411 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2470

Query: 781  EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 832
             + E    +++  L +  + E+A  +Q REE++RQQQ+    R      +EE RR + E 
Sbjct: 2471 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2530

Query: 833  ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
                RRKQEEL + +++   +     EE QR  E+ +L  E+  A L H EE
Sbjct: 2531 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2582



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
            +L Q ++  + + AKLEQ  ++   +A++  EE++RQ++   Q+ + L    EE R+R+ 
Sbjct: 2469 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2528

Query: 782  E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            E EE  RRKQEE              Q+ E++R+QQEE L         EE +R +E+L 
Sbjct: 2529 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2567

Query: 841  RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 893
              +E+  A  A  EE       A + L   R  ++  AA    E   +  R+++  QR +
Sbjct: 2568 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2627

Query: 894  E 894
            E
Sbjct: 2628 E 2628



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)

Query: 850  WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 903
            W  E+EE +   +      N    +E  + L  E E +++K  E+Q   + L+R+    +
Sbjct: 599  WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 658

Query: 904  EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 961
              +   Q   Q Q    ++L        + N    Q  + +  AE  +QKL+E   R+  
Sbjct: 659  PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 718

Query: 962  EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             ++      L   LQ  Q +++Q     G++S  +   K++++++
Sbjct: 719  CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 763


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score =  114 bits (286), Expect = 5e-25
 Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 778
            ALE+ +QL +A A    Q  REA+   +R +EE  R+EE     +QQ+  ++ + ++ R+
Sbjct: 1505 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1564

Query: 779  RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 812
              E E  A+ +Q EA  R R   E+EI                      ALR + EE E 
Sbjct: 1565 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1624

Query: 813  --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 869
              RQ QEEA  RL  + ++E +R++Q E+ L  + +  A+ ARE++ A + LEE RL+ E
Sbjct: 1625 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1683

Query: 870  EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 901
            E   RLR  E ER R+                            +LE   Q+E +   Q 
Sbjct: 1684 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1743

Query: 902  QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
            ++EA RR QQQ        + +++L + +L ++     +        Q +L+ AE +K +
Sbjct: 1744 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1803

Query: 954  EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
            EE ER+ R     EEQ  +QRE    L +Q+ ++Q++L+         GT +  L  +QE
Sbjct: 1804 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1851

Query: 1009 EARQMQKQQQQQQQHQ 1024
              R   + +Q +QQ Q
Sbjct: 1852 LIRLRAETEQGEQQRQ 1867



 Score =  110 bits (275), Expect = 9e-24
 Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
            ++LQQ  + + + L+Q R EAE   +  EE  + + +  R+  +  R+ +E ER ++  E
Sbjct: 2200 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2259

Query: 784  ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
            E A+ + +     E LR++ EQE A R Q E+   +Q++ A   +E+ ++  E+  +Q+ 
Sbjct: 2260 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2319

Query: 839  LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
             + +QE    +   EE + Q+ L      ++EE  RL+ E  E  R+  +V  ++EL   
Sbjct: 2320 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2370

Query: 899  RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 956
            R Q +E L +L+ + + +  A +     +T            Q     A +    +E  R
Sbjct: 2371 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2429

Query: 957  ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
             RQL EE   QQR L + + +++ Q  Q+ +    +   +   +   E+ QE+AR++Q+ 
Sbjct: 2430 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2486

Query: 1017 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1068
            ++Q  Q         Q+   A       +                    A +        
Sbjct: 2487 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2546

Query: 1069 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1122
            A+     +   + A +E      T + +   S      L +++    R+ +K+++E KLL
Sbjct: 2547 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2606

Query: 1123 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1182
            +L     K+++  T   EQ+L               SFL E +S  +   +I     + +
Sbjct: 2607 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2651

Query: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1242
            + ++  +  + +  + +  QQRQQQQ+ Q++Q+        + +Q ++  G+       +
Sbjct: 2652 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2710

Query: 1243 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1270
             Q  Q   QQ    A ++ + +++ +++
Sbjct: 2711 QQLEQQRRQQEELLAEENQRLREQLQLL 2738



 Score =  103 bits (256), Expect = 1e-21
 Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)

Query: 759  EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 816
            E LRR +EE  +  +Q+ EER+R  E E A  KQ +      + +    R+ +E +++ Q
Sbjct: 1476 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1535

Query: 817  EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 871
            EE +RR E     ++++R  QEEL  LR+  E E    AR+ E A+R    +RLR+EEE 
Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1591

Query: 872  -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 922
               RL+ E  ER+R   E E+Q    R +E   Q++Q QE   RL  Q Q + Q+  Q +
Sbjct: 1592 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1651

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
            +  +S    ++     + +A  +L E++   EE ER+LR+ +  + R++  AL+  Q+  
Sbjct: 1652 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1711

Query: 983  QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1037
            + +L         K +   +SL E     A+  ++ +++ QQ  +  RAR      L
Sbjct: 1712 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1768



 Score =  101 bits (251), Expect = 5e-21
 Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)

Query: 606  DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 662
            ++ERL  QQ   E   L +++    +Q  + + +AQ  AQ ++ A   QQ+ Q  ++ ++
Sbjct: 1483 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1542

Query: 663  FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 714
                +  +  Q    S+   +      S  E+Q  A Q    E           V  L L
Sbjct: 1543 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1598

Query: 715  DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 762
            + T    G A  +LQ L +A+A + E ++R+A+  A+R      +E +RKRQ E+     
Sbjct: 1599 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1657

Query: 763  -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 817
             + + E  R +Q      E  R + EE  RR ++  + R R+ ++AL   +   E + Q 
Sbjct: 1658 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1717

Query: 818  EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 871
            +     E+  + E   +++   + +  EEA + A+++ EA+R  EE    +E       E
Sbjct: 1718 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1777

Query: 872  AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 928
            A RLR + EE  +++   Q + E  ++ + ++EA RR + ++Q   Q++LA+ +L     
Sbjct: 1778 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1836

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
              + +      ++  L     +  + E++RQL EE+  R QRE   A Q++Q+ + +   
Sbjct: 1837 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1893

Query: 988  GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1020
                ++K     + LL  +   +EE+R   ++ +Q+
Sbjct: 1894 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1925



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)

Query: 613  QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 667
            +QELT L  Q++   +Q+ L+ ++  ++ A+  +AA    Q ++    + + +++   LK
Sbjct: 2322 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2381

Query: 668  MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 727
             RI  +N      R++ + D  +        ++           L +        L QL 
Sbjct: 2382 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2434

Query: 728  QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 787
            + + A+   L ++  + +M+A +E    K + EL +QQ+E+   Q++  R + ++E++A+
Sbjct: 2435 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2492

Query: 788  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
            +  EE    QR  E    RQR+ E   + E    R+ E  R +    +  +  RKQ EE 
Sbjct: 2493 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2550

Query: 848  AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
             +     E A +        LE  R + + +A RLR    E +R++ ++Q++ +L++ + 
Sbjct: 2551 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2610

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            ++ + +++ Q  Q+ Q L Q  L    +  Q+        Q    L ++ + E  + +QL
Sbjct: 2611 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2667

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQ+RQQ             QQ +      V+      +   E ++   R+ ++ QQ +
Sbjct: 2668 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2714

Query: 1021 QQHQQ 1025
            QQ +Q
Sbjct: 2715 QQRRQ 2719



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 771
            E++ Q +    A+ E+++ EAE  A+R    EE+  RQ EL  Q+ E  R+         
Sbjct: 1786 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1845

Query: 772  ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 802
               +QE  R R E           EEELAR ++E A   Q+ QE               +
Sbjct: 1846 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1905

Query: 803  ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 828
            A + + EEE R   E++ +RLE                                   R+R
Sbjct: 1906 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1965

Query: 829  EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 876
             E ER   E+L        L+ + E A K    E E  RRL E+    R R+EE+AA+ +
Sbjct: 1966 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 2025

Query: 877  HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 925
             + EE     RK  + E++RQK L    +RQR+Q +E +  L+   ++     A+++L  
Sbjct: 2026 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 2085

Query: 926  SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
                    +T   + QA L  A  ++L  E ER+ RE + R Q+ L  A ++  +Q++  
Sbjct: 2086 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2144

Query: 986  LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1025
            L     +       + L E  +QE ARQ+Q  Q+  Q+  Q
Sbjct: 2145 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2185



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)

Query: 607  QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            Q+RL  +QEL  L  + +  + Q+ L++++ A++   Q++AA ++Q++Q+L     + + 
Sbjct: 1843 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1894

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725
             K+R   + ++ S  R+     + S       + Q    E G   +L         A E 
Sbjct: 1895 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1940

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 782
             +    A+ AK +++  E +   +R E ER   E+L    E    + + E   + K  E 
Sbjct: 1941 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 2000

Query: 783  EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 829
            E L R  ++EA +R+R +E A + + + EER  Q     +  L R        L +RR+ 
Sbjct: 2001 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 2060

Query: 830  EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 859
            EEE                         R   E+ LR +E+   + AR+     EEE +R
Sbjct: 2061 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 2120

Query: 860  RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 906
            R  E R    L  EEEAAR R    EE ER + ++E  R      ++E  RQ Q  QEA 
Sbjct: 2121 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2180

Query: 907  -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957
             +RLQ +        QQ++Q  Q  L    +   Q    A  ++     AE  +++ ERE
Sbjct: 2181 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2240

Query: 958  RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
                  Q R+Q E  + L+Q  ++Q Q           +   K   E +QE AR+ Q +Q
Sbjct: 2241 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2291

Query: 1018 QQQQQHQ 1024
               +Q Q
Sbjct: 2292 AALRQKQ 2298



 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 777
            E+L++L + +A    Q RR  E  A+ + +  +R  +LR+  +  L RQ+        +R
Sbjct: 2001 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 2057

Query: 778  KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 830
            ++ EEE LA +   E+A   + E E+ L R R   E       Q + EA R+ +    EE
Sbjct: 2058 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 2117

Query: 831  EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 880
              RR+ EE ++K    EEEAA+  +    E E  + ++EE R    R E+E+AR     +
Sbjct: 2118 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2177

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
            E  +K L+ + +      +Q++QE  + LQQ+Q      + +  ++    +++     Q+
Sbjct: 2178 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2237

Query: 941  QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
            +   + +  Q  E ER +Q  EEQ + + +   A ++ +++ +Q+ +      + +   K
Sbjct: 2238 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2297

Query: 1001 SLLEIQQEEARQMQKQQQQQQ 1021
               + + E+ ++  +Q  +Q+
Sbjct: 2298 QAADAEMEKHKKFAEQTLRQK 2318



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)

Query: 723  LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 771
            +E+ +Q++ A     ++A+ E + + A    K  + ER  QEE      LR + E   ++
Sbjct: 1694 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1753

Query: 772  QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 826
            Q E ER R E E    R   K  EALR R + +E+A ++   + E  +Q+EEA R    R
Sbjct: 1754 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1813

Query: 827  RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 878
             + EE+  +Q EL           A +E E QR+L E     RL  E+E  RLR E    
Sbjct: 1814 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1862

Query: 879  EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 937
            E++R+  E E+ R Q+E     Q++QE    L + + + ++    L S +   ++S +T+
Sbjct: 1863 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1919

Query: 938  CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 989
             +S+  L       ++L EE  R R L EE +RQ++   +   +Q+ + +    +KL+  
Sbjct: 1920 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1979

Query: 990  GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
            G  ++                + L  + ++EA Q ++ ++Q  QH+
Sbjct: 1980 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 2025



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)

Query: 604  ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
            E + ERL R  E  A +Q + L+ Q    +    + LAQ +KA+  S+ ++Q  L+    
Sbjct: 1997 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 2052

Query: 664  QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 723
             TL+ R   +  I ++  S      G   EL+         E G +     DT       
Sbjct: 2053 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 2102

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 765
            E     ++  AA+ E+ RREAE R ++    EEE  RQ               EE RR +
Sbjct: 2103 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2162

Query: 766  EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
            E         L+  QE  +KR + EE    K      +Q+EQE+        ++  QQE+
Sbjct: 2163 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2210

Query: 819  ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
            ++  L++ R E E  R+  E     E E A+   E E AQ R      R  EEA RL+  
Sbjct: 2211 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2257

Query: 879  EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 935
             EE+ +   + Q   E +R ++ +QEA RR Q +Q   +Q+Q A  ++     + +Q+  
Sbjct: 2258 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2316

Query: 936  TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
               Q +  L+   +Q  E + ++ L +E+ +R + E  +A +Q+ Q +++  S
Sbjct: 2317 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2369



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)

Query: 612  RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 669
            RQ++L A  + +  + ++  +Q+  A  +  A+Q+KAAL  ++ ++L   +++ + L+ R
Sbjct: 2108 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2164

Query: 670  ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 721
               ++         +  + +   +    + +Q      Q T+ +  SV D        G 
Sbjct: 2165 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2219

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 773
            A    +  E+A+ A+++ ER  A+ R + EE ER +Q    + Q         E LR++ 
Sbjct: 2220 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2279

Query: 774  EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 815
            E+E  RR + E A  +Q++A                  + Q EQE+  LR Q EE + Q+
Sbjct: 2280 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2339

Query: 816  Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 857
               +E L+RL+    E   +R Q  EEL  +R Q EE +K              R+++  
Sbjct: 2340 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2399

Query: 858  QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 891
            QR L+E   +M++             EAARLR   EE             K K   VQ  
Sbjct: 2400 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2459

Query: 892  -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 943
                 + EL++Q+++  QE  RRLQ+ ++Q  QQLA+       T G Q    A + +  
Sbjct: 2460 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2513

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
               AE ++L + R  ++   Q R + +  +  ++Q ++  +KL      ++   T    L
Sbjct: 2514 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2571

Query: 1004 EIQQEEA 1010
            EIQ++++
Sbjct: 2572 EIQRQQS 2578



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)

Query: 725  QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            ++ ++ +A+A   E  +R      E+  K    E   QE++   Q   ++RQQ +    R
Sbjct: 2525 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2584

Query: 781  EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 827
              E +A  ++E+   +Q  + + L+ +     ++E+  Q+ +AL++         L+  R
Sbjct: 2585 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2644

Query: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 884
              E+E+ K E+L + +  +A +   E++  Q+++E+ R R+    EEA R +HE EE  R
Sbjct: 2645 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2704

Query: 885  KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
            ++ E  +Q E   Q+++QQE L   + Q+ ++QL  ++    +        TA Q  AT 
Sbjct: 2705 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2761

Query: 945  SL 946
            +L
Sbjct: 2762 TL 2763



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)

Query: 607  QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 666
            +  L +QQ+  A  Q + LQ  +  + QQ A+     Q+  L +++Q+QL +  +  + L
Sbjct: 2465 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2522

Query: 667  KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            K+R+++ +   +     +        + G        A+Q  V     V  L +      
Sbjct: 2523 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2579

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
               E+L++       + E+ ++EA++   + EE +  Q+E   Q+ + L++    E+   
Sbjct: 2580 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2639

Query: 781  EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 832
             + E    +++  L +  + E+A  +Q REE++RQQQ+    R      +EE RR + E 
Sbjct: 2640 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2699

Query: 833  ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
                RRKQEEL + +++   +     EE QR  E+ +L  E+  A L H EE
Sbjct: 2700 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2751



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
            +L Q ++  + + AKLEQ  ++   +A++  EE++RQ++   Q+ + L    EE R+R+ 
Sbjct: 2638 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2697

Query: 782  E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            E EE  RRKQEE              Q+ E++R+QQEE L         EE +R +E+L 
Sbjct: 2698 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2736

Query: 841  RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 893
              +E+  A  A  EE       A + L   R  ++  AA    E   +  R+++  QR +
Sbjct: 2737 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2796

Query: 894  E 894
            E
Sbjct: 2797 E 2797



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)

Query: 850  WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 903
            W  E+EE +   +      N    +E  + L  E E +++K  E+Q   + L+R+    +
Sbjct: 768  WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 827

Query: 904  EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 961
              +   Q   Q Q    ++L        + N    Q  + +  AE  +QKL+E   R+  
Sbjct: 828  PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 887

Query: 962  EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             ++      L   LQ  Q +++Q     G++S  +   K++++++
Sbjct: 888  CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 932


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score =  114 bits (286), Expect = 5e-25
 Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 778
            ALE+ +QL +A A    Q  REA+   +R +EE  R+EE     +QQ+  ++ + ++ R+
Sbjct: 1346 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1405

Query: 779  RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 812
              E E  A+ +Q EA  R R   E+EI                      ALR + EE E 
Sbjct: 1406 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1465

Query: 813  --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 869
              RQ QEEA  RL  + ++E +R++Q E+ L  + +  A+ ARE++ A + LEE RL+ E
Sbjct: 1466 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1524

Query: 870  EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 901
            E   RLR  E ER R+                            +LE   Q+E +   Q 
Sbjct: 1525 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1584

Query: 902  QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
            ++EA RR QQQ        + +++L + +L ++     +        Q +L+ AE +K +
Sbjct: 1585 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1644

Query: 954  EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
            EE ER+ R     EEQ  +QRE    L +Q+ ++Q++L+         GT +  L  +QE
Sbjct: 1645 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1692

Query: 1009 EARQMQKQQQQQQQHQ 1024
              R   + +Q +QQ Q
Sbjct: 1693 LIRLRAETEQGEQQRQ 1708



 Score =  110 bits (275), Expect = 9e-24
 Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
            ++LQQ  + + + L+Q R EAE   +  EE  + + +  R+  +  R+ +E ER ++  E
Sbjct: 2041 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2100

Query: 784  ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
            E A+ + +     E LR++ EQE A R Q E+   +Q++ A   +E+ ++  E+  +Q+ 
Sbjct: 2101 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2160

Query: 839  LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
             + +QE    +   EE + Q+ L      ++EE  RL+ E  E  R+  +V  ++EL   
Sbjct: 2161 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2211

Query: 899  RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 956
            R Q +E L +L+ + + +  A +     +T            Q     A +    +E  R
Sbjct: 2212 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2270

Query: 957  ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
             RQL EE   QQR L + + +++ Q  Q+ +    +   +   +   E+ QE+AR++Q+ 
Sbjct: 2271 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2327

Query: 1017 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1068
            ++Q  Q         Q+   A       +                    A +        
Sbjct: 2328 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2387

Query: 1069 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1122
            A+     +   + A +E      T + +   S      L +++    R+ +K+++E KLL
Sbjct: 2388 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2447

Query: 1123 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1182
            +L     K+++  T   EQ+L               SFL E +S  +   +I     + +
Sbjct: 2448 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2492

Query: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1242
            + ++  +  + +  + +  QQRQQQQ+ Q++Q+        + +Q ++  G+       +
Sbjct: 2493 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2551

Query: 1243 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1270
             Q  Q   QQ    A ++ + +++ +++
Sbjct: 2552 QQLEQQRRQQEELLAEENQRLREQLQLL 2579



 Score =  103 bits (256), Expect = 1e-21
 Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)

Query: 759  EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 816
            E LRR +EE  +  +Q+ EER+R  E E A  KQ +      + +    R+ +E +++ Q
Sbjct: 1317 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1376

Query: 817  EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 871
            EE +RR E     ++++R  QEEL  LR+  E E    AR+ E A+R    +RLR+EEE 
Sbjct: 1377 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1432

Query: 872  -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 922
               RL+ E  ER+R   E E+Q    R +E   Q++Q QE   RL  Q Q + Q+  Q +
Sbjct: 1433 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1492

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
            +  +S    ++     + +A  +L E++   EE ER+LR+ +  + R++  AL+  Q+  
Sbjct: 1493 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1552

Query: 983  QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1037
            + +L         K +   +SL E     A+  ++ +++ QQ  +  RAR      L
Sbjct: 1553 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1609



 Score =  101 bits (251), Expect = 5e-21
 Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)

Query: 606  DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 662
            ++ERL  QQ   E   L +++    +Q  + + +AQ  AQ ++ A   QQ+ Q  ++ ++
Sbjct: 1324 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1383

Query: 663  FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 714
                +  +  Q    S+   +      S  E+Q  A Q    E           V  L L
Sbjct: 1384 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1439

Query: 715  DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 762
            + T    G A  +LQ L +A+A + E ++R+A+  A+R      +E +RKRQ E+     
Sbjct: 1440 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1498

Query: 763  -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 817
             + + E  R +Q      E  R + EE  RR ++  + R R+ ++AL   +   E + Q 
Sbjct: 1499 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1558

Query: 818  EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 871
            +     E+  + E   +++   + +  EEA + A+++ EA+R  EE    +E       E
Sbjct: 1559 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1618

Query: 872  AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 928
            A RLR + EE  +++   Q + E  ++ + ++EA RR + ++Q   Q++LA+ +L     
Sbjct: 1619 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1677

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
              + +      ++  L     +  + E++RQL EE+  R QRE   A Q++Q+ + +   
Sbjct: 1678 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1734

Query: 988  GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1020
                ++K     + LL  +   +EE+R   ++ +Q+
Sbjct: 1735 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1766



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)

Query: 613  QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 667
            +QELT L  Q++   +Q+ L+ ++  ++ A+  +AA    Q ++    + + +++   LK
Sbjct: 2163 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2222

Query: 668  MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 727
             RI  +N      R++ + D  +        ++           L +        L QL 
Sbjct: 2223 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2275

Query: 728  QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 787
            + + A+   L ++  + +M+A +E    K + EL +QQ+E+   Q++  R + ++E++A+
Sbjct: 2276 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2333

Query: 788  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
            +  EE    QR  E    RQR+ E   + E    R+ E  R +    +  +  RKQ EE 
Sbjct: 2334 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2391

Query: 848  AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
             +     E A +        LE  R + + +A RLR    E +R++ ++Q++ +L++ + 
Sbjct: 2392 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2451

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            ++ + +++ Q  Q+ Q L Q  L    +  Q+        Q    L ++ + E  + +QL
Sbjct: 2452 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2508

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQ+RQQ             QQ +      V+      +   E ++   R+ ++ QQ +
Sbjct: 2509 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2555

Query: 1021 QQHQQ 1025
            QQ +Q
Sbjct: 2556 QQRRQ 2560



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 771
            E++ Q +    A+ E+++ EAE  A+R    EE+  RQ EL  Q+ E  R+         
Sbjct: 1627 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1686

Query: 772  ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 802
               +QE  R R E           EEELAR ++E A   Q+ QE               +
Sbjct: 1687 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1746

Query: 803  ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 828
            A + + EEE R   E++ +RLE                                   R+R
Sbjct: 1747 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1806

Query: 829  EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 876
             E ER   E+L        L+ + E A K    E E  RRL E+    R R+EE+AA+ +
Sbjct: 1807 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1866

Query: 877  HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 925
             + EE     RK  + E++RQK L    +RQR+Q +E +  L+   ++     A+++L  
Sbjct: 1867 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1926

Query: 926  SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
                    +T   + QA L  A  ++L  E ER+ RE + R Q+ L  A ++  +Q++  
Sbjct: 1927 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 1985

Query: 986  LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1025
            L     +       + L E  +QE ARQ+Q  Q+  Q+  Q
Sbjct: 1986 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2026



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)

Query: 607  QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            Q+RL  +QEL  L  + +  + Q+ L++++ A++   Q++AA ++Q++Q+L     + + 
Sbjct: 1684 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1735

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725
             K+R   + ++ S  R+     + S       + Q    E G   +L         A E 
Sbjct: 1736 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1781

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 782
             +    A+ AK +++  E +   +R E ER   E+L    E    + + E   + K  E 
Sbjct: 1782 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1841

Query: 783  EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 829
            E L R  ++EA +R+R +E A + + + EER  Q     +  L R        L +RR+ 
Sbjct: 1842 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1901

Query: 830  EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 859
            EEE                         R   E+ LR +E+   + AR+     EEE +R
Sbjct: 1902 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1961

Query: 860  RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 906
            R  E R    L  EEEAAR R    EE ER + ++E  R      ++E  RQ Q  QEA 
Sbjct: 1962 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2021

Query: 907  -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957
             +RLQ +        QQ++Q  Q  L    +   Q    A  ++     AE  +++ ERE
Sbjct: 2022 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2081

Query: 958  RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
                  Q R+Q E  + L+Q  ++Q Q           +   K   E +QE AR+ Q +Q
Sbjct: 2082 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2132

Query: 1018 QQQQQHQ 1024
               +Q Q
Sbjct: 2133 AALRQKQ 2139



 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 777
            E+L++L + +A    Q RR  E  A+ + +  +R  +LR+  +  L RQ+        +R
Sbjct: 1842 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1898

Query: 778  KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 830
            ++ EEE LA +   E+A   + E E+ L R R   E       Q + EA R+ +    EE
Sbjct: 1899 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1958

Query: 831  EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 880
              RR+ EE ++K    EEEAA+  +    E E  + ++EE R    R E+E+AR     +
Sbjct: 1959 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2018

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
            E  +K L+ + +      +Q++QE  + LQQ+Q      + +  ++    +++     Q+
Sbjct: 2019 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2078

Query: 941  QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
            +   + +  Q  E ER +Q  EEQ + + +   A ++ +++ +Q+ +      + +   K
Sbjct: 2079 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2138

Query: 1001 SLLEIQQEEARQMQKQQQQQQ 1021
               + + E+ ++  +Q  +Q+
Sbjct: 2139 QAADAEMEKHKKFAEQTLRQK 2159



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)

Query: 723  LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 771
            +E+ +Q++ A     ++A+ E + + A    K  + ER  QEE      LR + E   ++
Sbjct: 1535 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1594

Query: 772  QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 826
            Q E ER R E E    R   K  EALR R + +E+A ++   + E  +Q+EEA R    R
Sbjct: 1595 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1654

Query: 827  RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 878
             + EE+  +Q EL           A +E E QR+L E     RL  E+E  RLR E    
Sbjct: 1655 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1703

Query: 879  EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 937
            E++R+  E E+ R Q+E     Q++QE    L + + + ++    L S +   ++S +T+
Sbjct: 1704 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1760

Query: 938  CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 989
             +S+  L       ++L EE  R R L EE +RQ++   +   +Q+ + +    +KL+  
Sbjct: 1761 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1820

Query: 990  GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
            G  ++                + L  + ++EA Q ++ ++Q  QH+
Sbjct: 1821 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1866



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)

Query: 604  ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
            E + ERL R  E  A +Q + L+ Q    +    + LAQ +KA+  S+ ++Q  L+    
Sbjct: 1838 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1893

Query: 664  QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 723
             TL+ R   +  I ++  S      G   EL+         E G +     DT       
Sbjct: 1894 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1943

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 765
            E     ++  AA+ E+ RREAE R ++    EEE  RQ               EE RR +
Sbjct: 1944 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2003

Query: 766  EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
            E         L+  QE  +KR + EE    K      +Q+EQE+        ++  QQE+
Sbjct: 2004 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2051

Query: 819  ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
            ++  L++ R E E  R+  E     E E A+   E E AQ R      R  EEA RL+  
Sbjct: 2052 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2098

Query: 879  EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 935
             EE+ +   + Q   E +R ++ +QEA RR Q +Q   +Q+Q A  ++     + +Q+  
Sbjct: 2099 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2157

Query: 936  TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
               Q +  L+   +Q  E + ++ L +E+ +R + E  +A +Q+ Q +++  S
Sbjct: 2158 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2210



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)

Query: 612  RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 669
            RQ++L A  + +  + ++  +Q+  A  +  A+Q+KAAL  ++ ++L   +++ + L+ R
Sbjct: 1949 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2005

Query: 670  ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 721
               ++         +  + +   +    + +Q      Q T+ +  SV D        G 
Sbjct: 2006 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2060

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 773
            A    +  E+A+ A+++ ER  A+ R + EE ER +Q    + Q         E LR++ 
Sbjct: 2061 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2120

Query: 774  EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 815
            E+E  RR + E A  +Q++A                  + Q EQE+  LR Q EE + Q+
Sbjct: 2121 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2180

Query: 816  Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 857
               +E L+RL+    E   +R Q  EEL  +R Q EE +K              R+++  
Sbjct: 2181 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2240

Query: 858  QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 891
            QR L+E   +M++             EAARLR   EE             K K   VQ  
Sbjct: 2241 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2300

Query: 892  -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 943
                 + EL++Q+++  QE  RRLQ+ ++Q  QQLA+       T G Q    A + +  
Sbjct: 2301 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2354

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
               AE ++L + R  ++   Q R + +  +  ++Q ++  +KL      ++   T    L
Sbjct: 2355 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2412

Query: 1004 EIQQEEA 1010
            EIQ++++
Sbjct: 2413 EIQRQQS 2419



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)

Query: 725  QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            ++ ++ +A+A   E  +R      E+  K    E   QE++   Q   ++RQQ +    R
Sbjct: 2366 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2425

Query: 781  EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 827
              E +A  ++E+   +Q  + + L+ +     ++E+  Q+ +AL++         L+  R
Sbjct: 2426 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2485

Query: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 884
              E+E+ K E+L + +  +A +   E++  Q+++E+ R R+    EEA R +HE EE  R
Sbjct: 2486 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2545

Query: 885  KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
            ++ E  +Q E   Q+++QQE L   + Q+ ++QL  ++    +        TA Q  AT 
Sbjct: 2546 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2602

Query: 945  SL 946
            +L
Sbjct: 2603 TL 2604



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)

Query: 607  QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 666
            +  L +QQ+  A  Q + LQ  +  + QQ A+     Q+  L +++Q+QL +  +  + L
Sbjct: 2306 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2363

Query: 667  KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            K+R+++ +   +     +        + G        A+Q  V     V  L +      
Sbjct: 2364 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2420

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
               E+L++       + E+ ++EA++   + EE +  Q+E   Q+ + L++    E+   
Sbjct: 2421 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2480

Query: 781  EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 832
             + E    +++  L +  + E+A  +Q REE++RQQQ+    R      +EE RR + E 
Sbjct: 2481 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2540

Query: 833  ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
                RRKQEEL + +++   +     EE QR  E+ +L  E+  A L H EE
Sbjct: 2541 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2592



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
            +L Q ++  + + AKLEQ  ++   +A++  EE++RQ++   Q+ + L    EE R+R+ 
Sbjct: 2479 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2538

Query: 782  E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            E EE  RRKQEE              Q+ E++R+QQEE L         EE +R +E+L 
Sbjct: 2539 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2577

Query: 841  RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 893
              +E+  A  A  EE       A + L   R  ++  AA    E   +  R+++  QR +
Sbjct: 2578 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2637

Query: 894  E 894
            E
Sbjct: 2638 E 2638



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)

Query: 850  WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 903
            W  E+EE +   +      N    +E  + L  E E +++K  E+Q   + L+R+    +
Sbjct: 609  WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 668

Query: 904  EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 961
              +   Q   Q Q    ++L        + N    Q  + +  AE  +QKL+E   R+  
Sbjct: 669  PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 728

Query: 962  EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             ++      L   LQ  Q +++Q     G++S  +   K++++++
Sbjct: 729  CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 773


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score =  114 bits (286), Expect = 5e-25
 Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 778
            ALE+ +QL +A A    Q  REA+   +R +EE  R+EE     +QQ+  ++ + ++ R+
Sbjct: 1354 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1413

Query: 779  RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 812
              E E  A+ +Q EA  R R   E+EI                      ALR + EE E 
Sbjct: 1414 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1473

Query: 813  --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 869
              RQ QEEA  RL  + ++E +R++Q E+ L  + +  A+ ARE++ A + LEE RL+ E
Sbjct: 1474 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1532

Query: 870  EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 901
            E   RLR  E ER R+                            +LE   Q+E +   Q 
Sbjct: 1533 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1592

Query: 902  QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
            ++EA RR QQQ        + +++L + +L ++     +        Q +L+ AE +K +
Sbjct: 1593 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1652

Query: 954  EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
            EE ER+ R     EEQ  +QRE    L +Q+ ++Q++L+         GT +  L  +QE
Sbjct: 1653 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1700

Query: 1009 EARQMQKQQQQQQQHQ 1024
              R   + +Q +QQ Q
Sbjct: 1701 LIRLRAETEQGEQQRQ 1716



 Score =  110 bits (275), Expect = 9e-24
 Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
            ++LQQ  + + + L+Q R EAE   +  EE  + + +  R+  +  R+ +E ER ++  E
Sbjct: 2049 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2108

Query: 784  ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
            E A+ + +     E LR++ EQE A R Q E+   +Q++ A   +E+ ++  E+  +Q+ 
Sbjct: 2109 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2168

Query: 839  LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
             + +QE    +   EE + Q+ L      ++EE  RL+ E  E  R+  +V  ++EL   
Sbjct: 2169 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2219

Query: 899  RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 956
            R Q +E L +L+ + + +  A +     +T            Q     A +    +E  R
Sbjct: 2220 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2278

Query: 957  ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
             RQL EE   QQR L + + +++ Q  Q+ +    +   +   +   E+ QE+AR++Q+ 
Sbjct: 2279 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2335

Query: 1017 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1068
            ++Q  Q         Q+   A       +                    A +        
Sbjct: 2336 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2395

Query: 1069 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1122
            A+     +   + A +E      T + +   S      L +++    R+ +K+++E KLL
Sbjct: 2396 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2455

Query: 1123 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1182
            +L     K+++  T   EQ+L               SFL E +S  +   +I     + +
Sbjct: 2456 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2500

Query: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1242
            + ++  +  + +  + +  QQRQQQQ+ Q++Q+        + +Q ++  G+       +
Sbjct: 2501 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2559

Query: 1243 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1270
             Q  Q   QQ    A ++ + +++ +++
Sbjct: 2560 QQLEQQRRQQEELLAEENQRLREQLQLL 2587



 Score =  103 bits (256), Expect = 1e-21
 Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)

Query: 759  EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 816
            E LRR +EE  +  +Q+ EER+R  E E A  KQ +      + +    R+ +E +++ Q
Sbjct: 1325 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1384

Query: 817  EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 871
            EE +RR E     ++++R  QEEL  LR+  E E    AR+ E A+R    +RLR+EEE 
Sbjct: 1385 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1440

Query: 872  -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 922
               RL+ E  ER+R   E E+Q    R +E   Q++Q QE   RL  Q Q + Q+  Q +
Sbjct: 1441 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1500

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
            +  +S    ++     + +A  +L E++   EE ER+LR+ +  + R++  AL+  Q+  
Sbjct: 1501 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1560

Query: 983  QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1037
            + +L         K +   +SL E     A+  ++ +++ QQ  +  RAR      L
Sbjct: 1561 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1617



 Score =  101 bits (251), Expect = 5e-21
 Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)

Query: 606  DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 662
            ++ERL  QQ   E   L +++    +Q  + + +AQ  AQ ++ A   QQ+ Q  ++ ++
Sbjct: 1332 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1391

Query: 663  FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 714
                +  +  Q    S+   +      S  E+Q  A Q    E           V  L L
Sbjct: 1392 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1447

Query: 715  DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 762
            + T    G A  +LQ L +A+A + E ++R+A+  A+R      +E +RKRQ E+     
Sbjct: 1448 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1506

Query: 763  -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 817
             + + E  R +Q      E  R + EE  RR ++  + R R+ ++AL   +   E + Q 
Sbjct: 1507 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1566

Query: 818  EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 871
            +     E+  + E   +++   + +  EEA + A+++ EA+R  EE    +E       E
Sbjct: 1567 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1626

Query: 872  AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 928
            A RLR + EE  +++   Q + E  ++ + ++EA RR + ++Q   Q++LA+ +L     
Sbjct: 1627 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1685

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
              + +      ++  L     +  + E++RQL EE+  R QRE   A Q++Q+ + +   
Sbjct: 1686 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1742

Query: 988  GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1020
                ++K     + LL  +   +EE+R   ++ +Q+
Sbjct: 1743 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1774



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)

Query: 613  QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 667
            +QELT L  Q++   +Q+ L+ ++  ++ A+  +AA    Q ++    + + +++   LK
Sbjct: 2171 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2230

Query: 668  MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 727
             RI  +N      R++ + D  +        ++           L +        L QL 
Sbjct: 2231 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2283

Query: 728  QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 787
            + + A+   L ++  + +M+A +E    K + EL +QQ+E+   Q++  R + ++E++A+
Sbjct: 2284 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2341

Query: 788  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
            +  EE    QR  E    RQR+ E   + E    R+ E  R +    +  +  RKQ EE 
Sbjct: 2342 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2399

Query: 848  AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
             +     E A +        LE  R + + +A RLR    E +R++ ++Q++ +L++ + 
Sbjct: 2400 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2459

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            ++ + +++ Q  Q+ Q L Q  L    +  Q+        Q    L ++ + E  + +QL
Sbjct: 2460 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2516

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQ+RQQ             QQ +      V+      +   E ++   R+ ++ QQ +
Sbjct: 2517 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2563

Query: 1021 QQHQQ 1025
            QQ +Q
Sbjct: 2564 QQRRQ 2568



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 771
            E++ Q +    A+ E+++ EAE  A+R    EE+  RQ EL  Q+ E  R+         
Sbjct: 1635 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1694

Query: 772  ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 802
               +QE  R R E           EEELAR ++E A   Q+ QE               +
Sbjct: 1695 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1754

Query: 803  ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 828
            A + + EEE R   E++ +RLE                                   R+R
Sbjct: 1755 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1814

Query: 829  EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 876
             E ER   E+L        L+ + E A K    E E  RRL E+    R R+EE+AA+ +
Sbjct: 1815 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1874

Query: 877  HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 925
             + EE     RK  + E++RQK L    +RQR+Q +E +  L+   ++     A+++L  
Sbjct: 1875 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1934

Query: 926  SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
                    +T   + QA L  A  ++L  E ER+ RE + R Q+ L  A ++  +Q++  
Sbjct: 1935 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 1993

Query: 986  LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1025
            L     +       + L E  +QE ARQ+Q  Q+  Q+  Q
Sbjct: 1994 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2034



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)

Query: 607  QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            Q+RL  +QEL  L  + +  + Q+ L++++ A++   Q++AA ++Q++Q+L     + + 
Sbjct: 1692 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1743

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725
             K+R   + ++ S  R+     + S       + Q    E G   +L         A E 
Sbjct: 1744 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1789

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 782
             +    A+ AK +++  E +   +R E ER   E+L    E    + + E   + K  E 
Sbjct: 1790 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1849

Query: 783  EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 829
            E L R  ++EA +R+R +E A + + + EER  Q     +  L R        L +RR+ 
Sbjct: 1850 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1909

Query: 830  EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 859
            EEE                         R   E+ LR +E+   + AR+     EEE +R
Sbjct: 1910 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 1969

Query: 860  RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 906
            R  E R    L  EEEAAR R    EE ER + ++E  R      ++E  RQ Q  QEA 
Sbjct: 1970 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2029

Query: 907  -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957
             +RLQ +        QQ++Q  Q  L    +   Q    A  ++     AE  +++ ERE
Sbjct: 2030 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2089

Query: 958  RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
                  Q R+Q E  + L+Q  ++Q Q           +   K   E +QE AR+ Q +Q
Sbjct: 2090 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2140

Query: 1018 QQQQQHQ 1024
               +Q Q
Sbjct: 2141 AALRQKQ 2147



 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 777
            E+L++L + +A    Q RR  E  A+ + +  +R  +LR+  +  L RQ+        +R
Sbjct: 1850 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1906

Query: 778  KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 830
            ++ EEE LA +   E+A   + E E+ L R R   E       Q + EA R+ +    EE
Sbjct: 1907 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 1966

Query: 831  EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 880
              RR+ EE ++K    EEEAA+  +    E E  + ++EE R    R E+E+AR     +
Sbjct: 1967 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2026

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
            E  +K L+ + +      +Q++QE  + LQQ+Q      + +  ++    +++     Q+
Sbjct: 2027 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2086

Query: 941  QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
            +   + +  Q  E ER +Q  EEQ + + +   A ++ +++ +Q+ +      + +   K
Sbjct: 2087 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2146

Query: 1001 SLLEIQQEEARQMQKQQQQQQ 1021
               + + E+ ++  +Q  +Q+
Sbjct: 2147 QAADAEMEKHKKFAEQTLRQK 2167



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)

Query: 723  LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 771
            +E+ +Q++ A     ++A+ E + + A    K  + ER  QEE      LR + E   ++
Sbjct: 1543 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1602

Query: 772  QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 826
            Q E ER R E E    R   K  EALR R + +E+A ++   + E  +Q+EEA R    R
Sbjct: 1603 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1662

Query: 827  RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 878
             + EE+  +Q EL           A +E E QR+L E     RL  E+E  RLR E    
Sbjct: 1663 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1711

Query: 879  EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 937
            E++R+  E E+ R Q+E     Q++QE    L + + + ++    L S +   ++S +T+
Sbjct: 1712 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1768

Query: 938  CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 989
             +S+  L       ++L EE  R R L EE +RQ++   +   +Q+ + +    +KL+  
Sbjct: 1769 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1828

Query: 990  GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
            G  ++                + L  + ++EA Q ++ ++Q  QH+
Sbjct: 1829 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1874



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)

Query: 604  ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
            E + ERL R  E  A +Q + L+ Q    +    + LAQ +KA+  S+ ++Q  L+    
Sbjct: 1846 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1901

Query: 664  QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 723
             TL+ R   +  I ++  S      G   EL+         E G +     DT       
Sbjct: 1902 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1951

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 765
            E     ++  AA+ E+ RREAE R ++    EEE  RQ               EE RR +
Sbjct: 1952 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2011

Query: 766  EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
            E         L+  QE  +KR + EE    K      +Q+EQE+        ++  QQE+
Sbjct: 2012 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2059

Query: 819  ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
            ++  L++ R E E  R+  E     E E A+   E E AQ R      R  EEA RL+  
Sbjct: 2060 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2106

Query: 879  EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 935
             EE+ +   + Q   E +R ++ +QEA RR Q +Q   +Q+Q A  ++     + +Q+  
Sbjct: 2107 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2165

Query: 936  TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
               Q +  L+   +Q  E + ++ L +E+ +R + E  +A +Q+ Q +++  S
Sbjct: 2166 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2218



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)

Query: 612  RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 669
            RQ++L A  + +  + ++  +Q+  A  +  A+Q+KAAL  ++ ++L   +++ + L+ R
Sbjct: 1957 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2013

Query: 670  ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 721
               ++         +  + +   +    + +Q      Q T+ +  SV D        G 
Sbjct: 2014 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2068

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 773
            A    +  E+A+ A+++ ER  A+ R + EE ER +Q    + Q         E LR++ 
Sbjct: 2069 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2128

Query: 774  EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 815
            E+E  RR + E A  +Q++A                  + Q EQE+  LR Q EE + Q+
Sbjct: 2129 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2188

Query: 816  Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 857
               +E L+RL+    E   +R Q  EEL  +R Q EE +K              R+++  
Sbjct: 2189 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2248

Query: 858  QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 891
            QR L+E   +M++             EAARLR   EE             K K   VQ  
Sbjct: 2249 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2308

Query: 892  -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 943
                 + EL++Q+++  QE  RRLQ+ ++Q  QQLA+       T G Q    A + +  
Sbjct: 2309 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2362

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
               AE ++L + R  ++   Q R + +  +  ++Q ++  +KL      ++   T    L
Sbjct: 2363 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2420

Query: 1004 EIQQEEA 1010
            EIQ++++
Sbjct: 2421 EIQRQQS 2427



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)

Query: 725  QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            ++ ++ +A+A   E  +R      E+  K    E   QE++   Q   ++RQQ +    R
Sbjct: 2374 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2433

Query: 781  EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 827
              E +A  ++E+   +Q  + + L+ +     ++E+  Q+ +AL++         L+  R
Sbjct: 2434 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2493

Query: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 884
              E+E+ K E+L + +  +A +   E++  Q+++E+ R R+    EEA R +HE EE  R
Sbjct: 2494 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2553

Query: 885  KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
            ++ E  +Q E   Q+++QQE L   + Q+ ++QL  ++    +        TA Q  AT 
Sbjct: 2554 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2610

Query: 945  SL 946
            +L
Sbjct: 2611 TL 2612



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)

Query: 607  QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 666
            +  L +QQ+  A  Q + LQ  +  + QQ A+     Q+  L +++Q+QL +  +  + L
Sbjct: 2314 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2371

Query: 667  KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            K+R+++ +   +     +        + G        A+Q  V     V  L +      
Sbjct: 2372 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2428

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
               E+L++       + E+ ++EA++   + EE +  Q+E   Q+ + L++    E+   
Sbjct: 2429 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2488

Query: 781  EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 832
             + E    +++  L +  + E+A  +Q REE++RQQQ+    R      +EE RR + E 
Sbjct: 2489 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2548

Query: 833  ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
                RRKQEEL + +++   +     EE QR  E+ +L  E+  A L H EE
Sbjct: 2549 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2600



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
            +L Q ++  + + AKLEQ  ++   +A++  EE++RQ++   Q+ + L    EE R+R+ 
Sbjct: 2487 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2546

Query: 782  E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            E EE  RRKQEE              Q+ E++R+QQEE L         EE +R +E+L 
Sbjct: 2547 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2585

Query: 841  RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 893
              +E+  A  A  EE       A + L   R  ++  AA    E   +  R+++  QR +
Sbjct: 2586 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2645

Query: 894  E 894
            E
Sbjct: 2646 E 2646



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)

Query: 850  WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 903
            W  E+EE +   +      N    +E  + L  E E +++K  E+Q   + L+R+    +
Sbjct: 617  WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 676

Query: 904  EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 961
              +   Q   Q Q    ++L        + N    Q  + +  AE  +QKL+E   R+  
Sbjct: 677  PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 736

Query: 962  EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             ++      L   LQ  Q +++Q     G++S  +   K++++++
Sbjct: 737  CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 781


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score =  114 bits (286), Expect = 5e-25
 Identities = 113/376 (30%), Positives = 179/376 (47%), Gaps = 86/376 (22%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR---RQQEEILRRQQEEERK 778
            ALE+ +QL +A A    Q  REA+   +R +EE  R+EE     +QQ+  ++ + ++ R+
Sbjct: 1395 ALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1454

Query: 779  RREEEELARRKQEEALRRQR---EQEI----------------------ALRRQREEEE- 812
              E E  A+ +Q EA  R R   E+EI                      ALR + EE E 
Sbjct: 1455 SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA 1514

Query: 813  --RQQQEEALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRME 869
              RQ QEEA  RL  + ++E +R++Q E+ L  + +  A+ ARE++ A + LEE RL+ E
Sbjct: 1515 QKRQAQEEA-ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1573

Query: 870  EEAARLRHEEEERKRK----------------------------ELEVQRQKELMRQRQQ 901
            E   RLR  E ER R+                            +LE   Q+E +   Q 
Sbjct: 1574 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1633

Query: 902  QQEALRRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
            ++EA RR QQQ        + +++L + +L ++     +        Q +L+ AE +K +
Sbjct: 1634 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1693

Query: 954  EERERQLR-----EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
            EE ER+ R     EEQ  +QRE    L +Q+ ++Q++L+         GT +  L  +QE
Sbjct: 1694 EEAEREARRRGKAEEQAVRQRE----LAEQELEKQRQLA--------EGTAQQRLAAEQE 1741

Query: 1009 EARQMQKQQQQQQQHQ 1024
              R   + +Q +QQ Q
Sbjct: 1742 LIRLRAETEQGEQQRQ 1757



 Score =  110 bits (275), Expect = 9e-24
 Identities = 123/568 (21%), Positives = 248/568 (43%), Gaps = 50/568 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
            ++LQQ  + + + L+Q R EAE   +  EE  + + +  R+  +  R+ +E ER ++  E
Sbjct: 2090 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2149

Query: 784  ELARRKQE-----EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
            E A+ + +     E LR++ EQE A R Q E+   +Q++ A   +E+ ++  E+  +Q+ 
Sbjct: 2150 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKA 2209

Query: 839  LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
             + +QE    +   EE + Q+ L      ++EE  RL+ E  E  R+  +V  ++EL   
Sbjct: 2210 QV-EQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQV--EEELFSV 2260

Query: 899  RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE--R 956
            R Q +E L +L+ + + +  A +     +T            Q     A +    +E  R
Sbjct: 2261 RVQMEE-LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2319

Query: 957  ERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1016
             RQL EE   QQR L + + +++ Q  Q+ +    +   +   +   E+ QE+AR++Q+ 
Sbjct: 2320 LRQLAEEDLAQQRALAEKMLKEKMQAVQEAT---RLKAEAELLQQQKELAQEQARRLQED 2376

Query: 1017 QQQQQQH--------QQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSN 1068
            ++Q  Q         Q+   A       +                    A +        
Sbjct: 2377 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2436

Query: 1069 ADTKNSNMGFWDDAVKEVGPRNSTNKNKNNAS------LSKSVGVSNRQNKKVEEEEKLL 1122
            A+     +   + A +E      T + +   S      L +++    R+ +K+++E KLL
Sbjct: 2437 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2496

Query: 1123 KLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTS 1182
            +L     K+++  T   EQ+L               SFL E +S  +   +I     + +
Sbjct: 2497 QL-----KSEEMQTVQQEQLLQETQALQQ-------SFLSEKDSLLQRERFIEQ---EKA 2541

Query: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSV 1242
            + ++  +  + +  + +  QQRQQQQ+ Q++Q+        + +Q ++  G+       +
Sbjct: 2542 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ-EEL 2600

Query: 1243 FQTNQSNNQQSNFEAVQSGKKKKKQKMV 1270
             Q  Q   QQ    A ++ + +++ +++
Sbjct: 2601 QQLEQQRRQQEELLAEENQRLREQLQLL 2628



 Score =  103 bits (256), Expect = 1e-21
 Identities = 91/297 (30%), Positives = 151/297 (50%), Gaps = 22/297 (7%)

Query: 759  EELRRQQEE--ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 816
            E LRR +EE  +  +Q+ EER+R  E E A  KQ +      + +    R+ +E +++ Q
Sbjct: 1366 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1425

Query: 817  EEALRRLEERRREEEERRK-QEEL--LRKQEE-EAAKWAREEEEAQRRLEENRLRMEEE- 871
            EE +RR E     ++++R  QEEL  LR+  E E    AR+ E A+R    +RLR+EEE 
Sbjct: 1426 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER----SRLRIEEEI 1481

Query: 872  -AARLRHEEEERKR--KELEVQ----RQKELMRQRQQQQEALRRL--QQQQQQQQLAQMK 922
               RL+ E  ER+R   E E+Q    R +E   Q++Q QE   RL  Q Q + Q+  Q +
Sbjct: 1482 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1541

Query: 923  LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
            +  +S    ++     + +A  +L E++   EE ER+LR+ +  + R++  AL+  Q+  
Sbjct: 1542 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSA 1601

Query: 983  QQKLSG--WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1037
            + +L         K +   +SL E     A+  ++ +++ QQ  +  RAR      L
Sbjct: 1602 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL 1658



 Score =  101 bits (251), Expect = 5e-21
 Identities = 112/456 (24%), Positives = 213/456 (46%), Gaps = 54/456 (11%)

Query: 606  DQERLTRQQ---ELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQ 662
            ++ERL  QQ   E   L +++    +Q  + + +AQ  AQ ++ A   QQ+ Q  ++ ++
Sbjct: 1373 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRRE 1432

Query: 663  FQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS--------VWDLPL 714
                +  +  Q    S+   +      S  E+Q  A Q    E           V  L L
Sbjct: 1433 ----EAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQL 1488

Query: 715  DTTTP--GPALEQLQQLEKAKAAKLEQERREAEMRAKR------EEEERKRQEELR---- 762
            + T    G A  +LQ L +A+A + E ++R+A+  A+R      +E +RKRQ E+     
Sbjct: 1489 EATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASR 1547

Query: 763  -RQQEEILRRQQEE----ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 817
             + + E  R +Q      E  R + EE  RR ++  + R R+ ++AL   +   E + Q 
Sbjct: 1548 VKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQS 1607

Query: 818  EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME------EE 871
            +     E+  + E   +++   + +  EEA + A+++ EA+R  EE    +E       E
Sbjct: 1608 KRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANE 1667

Query: 872  AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ---QQQLAQMKLPSSST 928
            A RLR + EE  +++   Q + E  ++ + ++EA RR + ++Q   Q++LA+ +L     
Sbjct: 1668 ALRLRLQAEEVAQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1726

Query: 929  WGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
              + +      ++  L     +  + E++RQL EE+  R QRE   A Q++Q+ + +   
Sbjct: 1727 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE--- 1783

Query: 988  GWGNVSKPSGTTKSLLEIQ---QEEARQMQKQQQQQ 1020
                ++K     + LL  +   +EE+R   ++ +Q+
Sbjct: 1784 ----LAKVRAEMEVLLASKARAEEESRSTSEKSKQR 1815



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 98/425 (23%), Positives = 194/425 (45%), Gaps = 39/425 (9%)

Query: 613  QQELTAL-YQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQ----LALLLQQFQTLK 667
            +QELT L  Q++   +Q+ L+ ++  ++ A+  +AA    Q ++    + + +++   LK
Sbjct: 2212 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2271

Query: 668  MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 727
             RI  +N      R++ + D  +        ++           L +        L QL 
Sbjct: 2272 ARIEAEN------RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV-AAQEAARLRQLA 2324

Query: 728  QLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELAR 787
            + + A+   L ++  + +M+A +E    K + EL +QQ+E+   Q++  R + ++E++A+
Sbjct: 2325 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA--QEQARRLQEDKEQMAQ 2382

Query: 788  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
            +  EE    QR  E    RQR+ E   + E    R+ E  R +    +  +  RKQ EE 
Sbjct: 2383 QLAEETQGFQRTLEA--ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2440

Query: 848  AKWAREEEEAQRR-------LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQ 900
             +     E A +        LE  R + + +A RLR    E +R++ ++Q++ +L++ + 
Sbjct: 2441 GEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKS 2500

Query: 901  QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQL 960
            ++ + +++ Q  Q+ Q L Q  L    +  Q+        Q    L ++ + E  + +QL
Sbjct: 2501 EEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQL 2557

Query: 961  REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            REEQ+RQQ             QQ +      V+      +   E ++   R+ ++ QQ +
Sbjct: 2558 REEQQRQQ-------------QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604

Query: 1021 QQHQQ 1025
            QQ +Q
Sbjct: 2605 QQRRQ 2609



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 111/401 (27%), Positives = 173/401 (43%), Gaps = 100/401 (24%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQEELRRQQEEILRR--------- 771
            E++ Q +    A+ E+++ EAE  A+R    EE+  RQ EL  Q+ E  R+         
Sbjct: 1676 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1735

Query: 772  ---QQEEERKRRE-----------EEELARRKQEEALRRQREQE---------------I 802
               +QE  R R E           EEELAR ++E A   Q+ QE               +
Sbjct: 1736 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1795

Query: 803  ALRRQREEEERQQQEEALRRLE----------------------------------ERRR 828
            A + + EEE R   E++ +RLE                                   R+R
Sbjct: 1796 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1855

Query: 829  EEEERRKQEEL--------LRKQEEEAAKWAREEEEAQRRLEEN----RLRMEEEAARLR 876
             E ER   E+L        L+ + E A K    E E  RRL E+    R R+EE+AA+ +
Sbjct: 1856 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1915

Query: 877  HEEEE-----RKRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQL--AQMKLPS 925
             + EE     RK  + E++RQK L    +RQR+Q +E +  L+   ++     A+++L  
Sbjct: 1916 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL 1975

Query: 926  SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
                    +T   + QA L  A  ++L  E ER+ RE + R Q+ L  A ++  +Q++  
Sbjct: 1976 GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL-AAEEEAARQRKAA 2034

Query: 986  LSGWGNVSKPSGTTKSLLE-IQQEEARQMQKQQQQQQQHQQ 1025
            L     +       + L E  +QE ARQ+Q  Q+  Q+  Q
Sbjct: 2035 LEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2075



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 130/487 (26%), Positives = 212/487 (43%), Gaps = 100/487 (20%)

Query: 607  QERLTRQQELTALY-QMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665
            Q+RL  +QEL  L  + +  + Q+ L++++ A++   Q++AA ++Q++Q+L     + + 
Sbjct: 1733 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARL---QREAAAATQKRQEL-----EAEL 1784

Query: 666  LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725
             K+R   + ++ S  R+     + S       + Q    E G   +L         A E 
Sbjct: 1785 AKVRAEMEVLLASKARAEEESRSTS-----EKSKQRLEAEAGRFREL---------AEEA 1830

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE---ERKRREE 782
             +    A+ AK +++  E +   +R E ER   E+L    E    + + E   + K  E 
Sbjct: 1831 ARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAEN 1890

Query: 783  EELARRKQEEALRRQREQEIALRRQREEEERQQQ-----EEALRR--------LEERRRE 829
            E L R  ++EA +R+R +E A + + + EER  Q     +  L R        L +RR+ 
Sbjct: 1891 ERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQV 1950

Query: 830  EEE-------------------------RRKQEELLRKQEEEAAKWARE-----EEEAQR 859
            EEE                         R   E+ LR +E+   + AR+     EEE +R
Sbjct: 1951 EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRR 2010

Query: 860  RLEENR----LRMEEEAARLRH---EEEERKRKELEVQR------QKELMRQRQQQQEAL 906
            R  E R    L  EEEAAR R    EE ER + ++E  R      ++E  RQ Q  QEA 
Sbjct: 2011 REAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAA 2070

Query: 907  -RRLQQQ--------QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957
             +RLQ +        QQ++Q  Q  L    +   Q    A  ++     AE  +++ ERE
Sbjct: 2071 QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAERE 2130

Query: 958  RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
                  Q R+Q E  + L+Q  ++Q Q           +   K   E +QE AR+ Q +Q
Sbjct: 2131 ----AAQSRRQVEEAERLKQSAEEQAQ-----ARAQAQAAAEKLRKEAEQEAARRAQAEQ 2181

Query: 1018 QQQQQHQ 1024
               +Q Q
Sbjct: 2182 AALRQKQ 2188



 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 80/321 (24%), Positives = 156/321 (48%), Gaps = 26/321 (8%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE------EER 777
            E+L++L + +A    Q RR  E  A+ + +  +R  +LR+  +  L RQ+        +R
Sbjct: 1891 ERLRRLAEDEAF---QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1947

Query: 778  KRREEEELARRKQ-EEALRRQREQEIALRRQREEEE------RQQQEEALRRLEERRREE 830
            ++ EEE LA +   E+A   + E E+ L R R   E       Q + EA R+ +    EE
Sbjct: 1948 RQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEE 2007

Query: 831  EERRKQEELLRKQ---EEEAAKWAR----EEEEAQRRLEENRL---RMEEEAARLRHEEE 880
              RR+ EE ++K    EEEAA+  +    E E  + ++EE R    R E+E+AR     +
Sbjct: 2008 RRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQ 2067

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
            E  +K L+ + +      +Q++QE  + LQQ+Q      + +  ++    +++     Q+
Sbjct: 2068 EAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQA 2127

Query: 941  QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
            +   + +  Q  E ER +Q  EEQ + + +   A ++ +++ +Q+ +      + +   K
Sbjct: 2128 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2187

Query: 1001 SLLEIQQEEARQMQKQQQQQQ 1021
               + + E+ ++  +Q  +Q+
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQK 2208



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 96/346 (27%), Positives = 166/346 (47%), Gaps = 58/346 (16%)

Query: 723  LEQLQQLEKA-----KAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRR 771
            +E+ +Q++ A     ++A+ E + + A    K  + ER  QEE      LR + E   ++
Sbjct: 1584 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1643

Query: 772  QQEEERKRREEEELARR---KQEEALR-RQREQEIALRRQ-REEEERQQQEEALRRLEER 826
            Q E ER R E E    R   K  EALR R + +E+A ++   + E  +Q+EEA R    R
Sbjct: 1644 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1703

Query: 827  RREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE----NRLRMEEEAARLRHE---- 878
             + EE+  +Q EL           A +E E QR+L E     RL  E+E  RLR E    
Sbjct: 1704 GKAEEQAVRQREL-----------AEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQG 1752

Query: 879  EEERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTA 937
            E++R+  E E+ R Q+E     Q++QE    L + + + ++    L S +   ++S +T+
Sbjct: 1753 EQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVL---LASKARAEEESRSTS 1809

Query: 938  CQSQATL--SLAEIQKLEEE--RERQLREEQRRQQRELMKALQQQQQQQQ----QKLSGW 989
             +S+  L       ++L EE  R R L EE +RQ++   +   +Q+ + +    +KL+  
Sbjct: 1810 EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1869

Query: 990  GNVSK-----------PSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
            G  ++                + L  + ++EA Q ++ ++Q  QH+
Sbjct: 1870 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1915



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 113/413 (27%), Positives = 185/413 (44%), Gaps = 69/413 (16%)

Query: 604  ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
            E + ERL R  E  A +Q + L+ Q    +    + LAQ +KA+  S+ ++Q  L+    
Sbjct: 1887 EAENERLRRLAEDEA-FQRRRLEEQAAQHKADIEERLAQLRKAS-DSELERQKGLVED-- 1942

Query: 664  QTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPAL 723
             TL+ R   +  I ++  S      G   EL+         E G +     DT       
Sbjct: 1943 -TLRQRRQVEEEILALKASFEKAAAGKA-ELE--------LELGRIRSNAEDTLRSKEQA 1992

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKRE---EEERKRQ---------------EELRRQQ 765
            E     ++  AA+ E+ RREAE R ++    EEE  RQ               EE RR +
Sbjct: 1993 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLR 2052

Query: 766  EEI-------LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
            E         L+  QE  +KR + EE    K      +Q+EQE+        ++  QQE+
Sbjct: 2053 ERAEQESARQLQLAQEAAQKRLQAEE----KAHAFAVQQKEQEL--------QQTLQQEQ 2100

Query: 819  ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
            ++  L++ R E E  R+  E     E E A+   E E AQ R      R  EEA RL+  
Sbjct: 2101 SV--LDQLRGEAEAARRAAE-----EAEEARVQAEREAAQSR------RQVEEAERLKQS 2147

Query: 879  EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ---QQQQLAQMKLPSSSTWGQQSNT 935
             EE+ +   + Q   E +R ++ +QEA RR Q +Q   +Q+Q A  ++     + +Q+  
Sbjct: 2148 AEEQAQARAQAQAAAEKLR-KEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR 2206

Query: 936  TACQSQATLSLAEIQKLEEERERQLREEQ-RRQQRELMKALQQQQQQQQQKLS 987
               Q +  L+   +Q  E + ++ L +E+ +R + E  +A +Q+ Q +++  S
Sbjct: 2207 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2259



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 122/487 (25%), Positives = 218/487 (44%), Gaps = 104/487 (21%)

Query: 612  RQQELTALYQMQHLQYQQFLIQQQYA--QVLAQQQKAALSSQQQQQLALLLQQFQTLKMR 669
            RQ++L A  + +  + ++  +Q+  A  +  A+Q+KAAL  ++ ++L   +++ + L+ R
Sbjct: 1998 RQRQLAAEEERRRREAEE-RVQKSLAAEEEAARQRKAAL--EEVERLKAKVEEARRLRER 2054

Query: 670  ISDQNIIP------SVTRSVSVPDTGSIWELQPTAS--QPTVWEGGSVWDLPLDTTTPGP 721
               ++         +  + +   +    + +Q      Q T+ +  SV D        G 
Sbjct: 2055 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD-----QLRGE 2109

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE--------EILRRQQ 773
            A    +  E+A+ A+++ ER  A+ R + EE ER +Q    + Q         E LR++ 
Sbjct: 2110 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2169

Query: 774  EEERKRREEEELARRKQEEAL-----------------RRQREQEIA-LRRQREEEERQQ 815
            E+E  RR + E A  +Q++A                  + Q EQE+  LR Q EE + Q+
Sbjct: 2170 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2229

Query: 816  Q--EEALRRLEERRREEEERRKQ--EEL--LRKQEEEAAKWA------------REEEEA 857
               +E L+RL+    E   +R Q  EEL  +R Q EE +K              R+++  
Sbjct: 2230 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2289

Query: 858  QRRLEENRLRMEE-------------EAARLRHEEEER------------KRKELEVQR- 891
            QR L+E   +M++             EAARLR   EE             K K   VQ  
Sbjct: 2290 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2349

Query: 892  -----QKELMRQRQQ-QQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTACQSQAT 943
                 + EL++Q+++  QE  RRLQ+ ++Q  QQLA+       T G Q    A + +  
Sbjct: 2350 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAE------ETQGFQRTLEAERQRQL 2403

Query: 944  LSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
               AE ++L + R  ++   Q R + +  +  ++Q ++  +KL      ++   T    L
Sbjct: 2404 EMSAEAERL-KLRVAEMSRAQARAEEDAQR-FRKQAEEIGEKLHRTELATQEKVTLVQTL 2461

Query: 1004 EIQQEEA 1010
            EIQ++++
Sbjct: 2462 EIQRQQS 2468



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 62/242 (25%), Positives = 121/242 (50%), Gaps = 23/242 (9%)

Query: 725  QLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            ++ ++ +A+A   E  +R      E+  K    E   QE++   Q   ++RQQ +    R
Sbjct: 2415 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2474

Query: 781  EEEELARRKQEEALRRQREQEIALRRQR----EEEERQQQEEALRR---------LEERR 827
              E +A  ++E+   +Q  + + L+ +     ++E+  Q+ +AL++         L+  R
Sbjct: 2475 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRER 2534

Query: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME---EEAARLRHEEEERKR 884
              E+E+ K E+L + +  +A +   E++  Q+++E+ R R+    EEA R +HE EE  R
Sbjct: 2535 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR 2594

Query: 885  KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
            ++ E  +Q E   Q+++QQE L   + Q+ ++QL  ++    +        TA Q  AT 
Sbjct: 2595 RKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2651

Query: 945  SL 946
            +L
Sbjct: 2652 TL 2653



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 73/292 (25%), Positives = 136/292 (46%), Gaps = 23/292 (7%)

Query: 607  QERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTL 666
            +  L +QQ+  A  Q + LQ  +  + QQ A+     Q+  L +++Q+QL +  +  + L
Sbjct: 2355 EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRT-LEAERQRQLEMSAEA-ERL 2412

Query: 667  KMRISDQNIIPSVTRSVS------VPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPG 720
            K+R+++ +   +     +        + G        A+Q  V     V  L +      
Sbjct: 2413 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT---LVQTLEIQRQQSD 2469

Query: 721  PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
               E+L++       + E+ ++EA++   + EE +  Q+E   Q+ + L++    E+   
Sbjct: 2470 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2529

Query: 781  EEEELARRKQEEALRRQREQEIALRRQ-REEEERQQQEEALRR------LEERRREEEE- 832
             + E    +++  L +  + E+A  +Q REE++RQQQ+    R      +EE RR + E 
Sbjct: 2530 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2589

Query: 833  ----RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
                RRKQEEL + +++   +     EE QR  E+ +L  E+  A L H EE
Sbjct: 2590 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2641



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 29/181 (16%)

Query: 722  ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
            +L Q ++  + + AKLEQ  ++   +A++  EE++RQ++   Q+ + L    EE R+R+ 
Sbjct: 2528 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2587

Query: 782  E-EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
            E EE  RRKQEE              Q+ E++R+QQEE L         EE +R +E+L 
Sbjct: 2588 EAEEGVRRKQEEL-------------QQLEQQRRQQEELL--------AEENQRLREQLQ 2626

Query: 841  RKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAARLRHEEE-ERKRKELEVQRQK 893
              +E+  A  A  EE       A + L   R  ++  AA    E   +  R+++  QR +
Sbjct: 2627 LLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQ 2686

Query: 894  E 894
            E
Sbjct: 2687 E 2687



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 8/165 (4%)

Query: 850  WAREEEEAQRRLE-----ENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQ 903
            W  E+EE +   +      N    +E  + L  E E +++K  E+Q   + L+R+    +
Sbjct: 658  WLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPAR 717

Query: 904  EALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE--IQKLEEERERQLR 961
              +   Q   Q Q    ++L        + N    Q  + +  AE  +QKL+E   R+  
Sbjct: 718  PTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYS 777

Query: 962  EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             ++      L   LQ  Q +++Q     G++S  +   K++++++
Sbjct: 778  CDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLK 822


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score =  113 bits (282), Expect = 1e-24
 Identities = 101/337 (29%), Positives = 166/337 (49%), Gaps = 50/337 (14%)

Query: 706  GGSVWDLPLDTTTP-------GPA-LEQLQQLEKAKAAKLEQERREAEMRAKREEEE--- 754
            G S++ L   T  P       GP+ +EQLQ        +LE   R+ +   +  +     
Sbjct: 134  GRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLL 193

Query: 755  RKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQ 814
             +RQEE  R+QEE LR Q  EER R +EE L   +QEE LR Q E      R RE+EER 
Sbjct: 194  NRRQEERLREQEERLREQ--EERLREQEERLC--EQEERLREQEE------RLREQEERL 243

Query: 815  -QQEEALRRLEERRREEEER--------RKQEELLRKQEEEAAKWAREEEEAQRRLEENR 865
             +QEE LR  EER  E+EER        R+QEE L +QEE   +      E + RL E  
Sbjct: 244  CEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQE 303

Query: 866  LRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 925
             R+ E+  RL  +EE  + +E  +  Q++L  Q +  +E  + L+Q+++Q++  ++    
Sbjct: 304  ERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLL--- 360

Query: 926  SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
                           +    L E+++L E+ ER  ++++R  Q+E ++ L++ ++ ++  
Sbjct: 361  ---------------ERERLLEEVEELLEQ-ERLRQQDERLWQQETLQELERLRELERML 404

Query: 986  LSGWGNVSKPSGTTKS-LLEIQQEEARQMQKQQQQQQ 1021
              GW  + +     +S   E+  E    +Q +QQ ++
Sbjct: 405  ELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 441



 Score =  106 bits (264), Expect = 2e-22
 Identities = 93/274 (33%), Positives = 141/274 (51%), Gaps = 40/274 (14%)

Query: 723 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE-----EER 777
           L  L + ++ +  + E+  RE E R + +EE    QEE  R+QEE LR Q+E     EER
Sbjct: 190 LSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEER 249

Query: 778 KRREEEELARRKQE--EALRRQREQEIALRRQRE-----EEERQQQEEALRRLEERRREE 830
            R  EE L  +++   E   R REQE  L  Q E     EE  ++QEE L   EER RE+
Sbjct: 250 LREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQ 309

Query: 831 EERR-KQEELLRKQEE---EAAKWAREE---EEAQRRLEENRLRMEEEAARLRHEEEERK 883
           EER  +QEE LR+QEE   E  K   +E   EE ++ LE+ R + E+E    R  E ER 
Sbjct: 310 EERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQE----RLLERERL 365

Query: 884 RKELEVQRQKELMRQRQQ---QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
            +E+E   ++E +RQ+ +   QQE L+ L++ ++ +++ ++               A   
Sbjct: 366 LEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLEL------------GWEALYE 413

Query: 941 QATLSLAEIQKLEEERERQLREEQRRQQRELMKA 974
           Q     +  ++L  E +  L+ EQ  Q +EL K+
Sbjct: 414 QRAEPRSGFEELNNENKSTLQLEQ--QVKELKKS 445



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 74/261 (28%), Positives = 132/261 (50%), Gaps = 27/261 (10%)

Query: 772  QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEE 831
            Q E    R+E E + R+ Q E    +  Q ++L  +R+EE  ++QEE LR  EER RE+E
Sbjct: 163  QDETNHLRKELESVGRQLQAEV---ENNQMLSLLNRRQEERLREQEERLREQEERLREQE 219

Query: 832  ERR-KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
            ER  +QEE LR+QEE   +      E + RL E+  R+ E+  RL  +EE  + +E  + 
Sbjct: 220  ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLH 279

Query: 891  RQKE-LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 949
             Q+E L  Q ++ +E   RL +Q+++ +  + +L       ++     C+ +    L   
Sbjct: 280  EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQE---KLPGQ 336

Query: 950  QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1009
            ++L EE E+ L +E+R++++E +   ++  ++ ++ L                   +QE 
Sbjct: 337  ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELL-------------------EQER 377

Query: 1010 ARQMQKQQQQQQQHQQPNRAR 1030
             RQ  ++  QQ+  Q+  R R
Sbjct: 378  LRQQDERLWQQETLQELERLR 398



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 21/147 (14%)

Query: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQ---------E 774
           EQ ++L + +    EQE+   + R   E E+   QE  + +QE +L R++         E
Sbjct: 315 EQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLE 374

Query: 775 EERKRREEEELARRKQEEALRRQREQE-------IALRRQREE-----EERQQQEEALRR 822
           +ER R+++E L +++  + L R RE E        AL  QR E     EE   + ++  +
Sbjct: 375 QERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQ 434

Query: 823 LEERRREEEERRKQEELLRKQEEEAAK 849
           LE++ +E ++    EE    +   AA+
Sbjct: 435 LEQQVKELKKSGGAEEPRGSESAAAAR 461


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
            sapiens]
          Length = 600

 Score =  108 bits (270), Expect = 3e-23
 Identities = 80/322 (24%), Positives = 158/322 (49%), Gaps = 16/322 (4%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
            ++ ++  + K    +++R     R + +E ER+   E  RQ+E+   RQ+E ER+   E 
Sbjct: 76   DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135

Query: 784  ELARRKQEEALR---RQREQEIALRRQREEEERQQQE---EALRRLEERRREEEERRKQE 837
            E  R +Q +  R   RQR+ E    RQ + E ++Q E   +  R  E+ R+E  ER +Q 
Sbjct: 136  ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195

Query: 838  ELLRKQEEEAAKWAREEE-------EAQRRLEENRLR-MEEEAARLRHEEEERKR-KELE 888
            E   K E+  ++  RE E       E +R+ + +R R  + +  R R ++ ER+R  E E
Sbjct: 196  EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255

Query: 889  VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 948
             +R KE  R+R + ++  RR +++++Q    + +        ++      + +       
Sbjct: 256  TERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR 315

Query: 949  IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
             ++ E ERER+ RE QR  +R+  K  ++++++Q +        +   G  ++  E ++E
Sbjct: 316  KRERERERERE-RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374

Query: 1009 EARQMQKQQQQQQQHQQPNRAR 1030
              R  Q  ++++++ +  +R R
Sbjct: 375  RERDRQSAREREERERDRDRDR 396



 Score =  105 bits (263), Expect = 2e-22
 Identities = 78/320 (24%), Positives = 166/320 (51%), Gaps = 22/320 (6%)

Query: 720  GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEE-----RKRQEELRRQQEEILRRQQE 774
            G   E+ +Q E+ +  +  Q  RE + + +R  E+     R R  E +R +E+   RQ +
Sbjct: 51   GDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTD 110

Query: 775  EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE-EEER 833
             ER R+ E+E  R+K+ E   R+ E+E    R R+ + ++++E      +ER R+ + ER
Sbjct: 111  RERDRQREKERNRQKERE---RETEREGERGRDRQTDGQRERERQRDAEKERERQTDRER 167

Query: 834  RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK 893
            ++Q E  R++E E  K  +E  E +R+ E+     +  + R R  E ER+  E E +R++
Sbjct: 168  QRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE-TETETERKR 226

Query: 894  ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
            +  R+R +Q++  R  ++Q ++++ ++ +        ++ +             +  + +
Sbjct: 227  QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD----------RDRDRRQ 276

Query: 954  EERERQL-REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1012
            +ERERQ  R+ QRR +R+     ++++Q+++++        +     +   E Q+E  R 
Sbjct: 277  KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD 336

Query: 1013 MQKQQQQQQQHQ-QPNRARN 1031
             +K+++++++ Q + +R RN
Sbjct: 337  REKERERKRKRQTEMDRERN 356



 Score =  104 bits (260), Expect = 5e-22
 Identities = 74/324 (22%), Positives = 160/324 (49%), Gaps = 26/324 (8%)

Query: 727  QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 786
            ++ E+ + A+ E+ER+    R ++ E  R+++ E  + ++E   R+++ E++ + E+  +
Sbjct: 147  RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206

Query: 787  RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE-----EEERRKQEELLR 841
             R +E    R+ E E   +RQ + E  +Q++    R ++  RE     E ER K+ E  R
Sbjct: 207  ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266

Query: 842  KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR-----KELEVQRQKELM 896
             ++ +  +  +E E    R  + R   + E  R R  + ER+R     ++ E +R++E  
Sbjct: 267  DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326

Query: 897  RQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 956
            R+RQ++ E  R  ++++++++  +M    +   G++    A +          ++ E ER
Sbjct: 327  RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERE---------RERERER 377

Query: 957  ERQLREEQRRQQRELMKALQQQQQQQQQK-LSGWGNVSKPSGTTKSL-LEIQQEEARQMQ 1014
            +RQ   E+  ++R+  +  Q+++++Q +K   G     K     K    E  +E  R+ +
Sbjct: 378  DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437

Query: 1015 KQQ-----QQQQQHQQPNRARNNT 1033
            KQ+     +++Q  +Q  R R  +
Sbjct: 438  KQKGRERDRERQTDRQAGRQRKRS 461



 Score =  100 bits (249), Expect = 9e-21
 Identities = 69/325 (21%), Positives = 155/325 (47%), Gaps = 15/325 (4%)

Query: 707  GSVW---DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR 763
            G++W    +PLD +   P  +     E  +   L Q  ++A+     ++ ER RQ+E  R
Sbjct: 14   GTLWVEVTIPLDFSRRRPGSQ-----ESPRRRGLGQAHKDAD----GDDRERNRQKERER 64

Query: 764  QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 823
            ++E+    ++ + ++ R  E+   RK++    RQR++E    RQ + E  +Q+E+   R 
Sbjct: 65   RREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQ 124

Query: 824  EERRREEE---ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
            +ER RE E   ER +  +   ++E E  + A +E E Q   E  R            E+ 
Sbjct: 125  KERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN 184

Query: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQS 940
             ++R+E E QR+KE   + +  +    R ++++ + +  + +        Q+      + 
Sbjct: 185  RQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREK 244

Query: 941  QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
            QA    A  ++ E ++ER+   ++ R +    K  ++Q  +++Q+ +     ++     +
Sbjct: 245  QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304

Query: 1001 SLLEIQQEEARQMQKQQQQQQQHQQ 1025
               E ++E  R+ +++++++++ ++
Sbjct: 305  RERERERERNRKRERERERERERER 329



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 63/264 (23%), Positives = 124/264 (46%), Gaps = 22/264 (8%)

Query: 738  EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ 797
            +++R+    R K+ E ER  + E  R +E    R ++ +R RR++E   +  ++   R +
Sbjct: 233  DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292

Query: 798  REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA 857
            R++E   +R+R+ E  +++E   +R  ER RE E  R++E    +++E   K  R+ E  
Sbjct: 293  RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352

Query: 858  QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 917
            + R  +       +A R R  E ER R+    + ++E  R R +Q+E  R+ ++ +  Q+
Sbjct: 353  RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412

Query: 918  LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQ 977
                                 +++      + ++ E  RER  RE ++++ RE  +  Q 
Sbjct: 413  ---------------------ETEKQREREKDRESERGRERG-REREKQKGRERDRERQT 450

Query: 978  QQQQQQQKLSGWGNVSKPSGTTKS 1001
             +Q  +Q+      V+ P  T +S
Sbjct: 451  DRQAGRQRKRSTLYVNPPPRTARS 474



 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 67/219 (30%), Positives = 118/219 (53%), Gaps = 20/219 (9%)

Query: 724 EQLQQLEKAKAAKLEQER-------REAEMRAKREEEERKRQEELRRQQEEILRRQQEEE 776
           E+ +Q E+ +A++ E ER       R+ +    R ++ER+RQ + +RQ+     R+ E +
Sbjct: 241 EREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK 300

Query: 777 RKRREEEELAR-----RKQEEALRRQREQEIALRRQREEE-ERQQQEEALRRLEERRREE 830
           R+R+ E E  R     R++E    R+RE++    R RE+E ER+++ +     E  R+  
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360

Query: 831 EERRKQEELLRKQEEEAAKW-AREEEEAQR-----RLEENRLRMEEEAARLRHEEEERKR 884
            E R+Q E  R++E E  +  ARE EE +R     R +E   + E++    R  E++R+R
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER 420

Query: 885 -KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922
            K+ E +R +E  R+R++Q+   R  ++Q  +Q   Q K
Sbjct: 421 EKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 63/227 (27%), Positives = 102/227 (44%), Gaps = 23/227 (10%)

Query: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRR----QQEEILRRQQEEERKR 779
           E  ++ E+ +  + E+ER     R +  E ER+RQ E  R    ++E   +RQ E +R+R
Sbjct: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355

Query: 780 -REEEELARRKQEEALRRQREQEIALRRQREEEE----RQQQEEALRRLEERRREEEERR 834
            R+     RR+ E    R+RE++    R+REE E    R +Q+E  R+ E+ R  + E  
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETE 415

Query: 835 KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 894
           KQ E  + +E E  +    E E Q+  E +R R  +     R    +RKR  L V     
Sbjct: 416 KQREREKDRESERGRERGREREKQKGRERDRERQTD-----RQAGRQRKRSTLYVNPPPR 470

Query: 895 LMRQRQQQQEALR-----RLQQQQQQQQLAQMKLPSSSTWGQQSNTT 936
             R    Q +  R     R +   +  + A  + P    WG+ +  +
Sbjct: 471 TARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFP----WGRPAKAS 513



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 55/264 (20%), Positives = 96/264 (36%), Gaps = 41/264 (15%)

Query: 153 REMHRSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQN 212
           RE  R +  +   DR+ EK   +   R    E       R+ E  R    + +  RE Q 
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETE-------REGERGRDRQTDGQRERERQR 153

Query: 213 GEDEDGGWRLAGSR-RDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRV 271
             +++   +    R R  ER R    +  ++   R   ER+R  E    DR  ERG  R 
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213

Query: 272 RSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEG 331
           R      + +R                               K     E++   +   E 
Sbjct: 214 RERETETETER-------------------------------KRQTDRERDRQRKTERER 242

Query: 332 EECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA 391
           E+ ++ E + +E   E DK  ++E ++ DR      +E  + +    +  T  D +++  
Sbjct: 243 EKQAERERA-SERETERDKERERERDR-DRDRDRRQKERERQTDRKRQRRTERDRETERK 300

Query: 392 SQFERKDEPKTEQTEKAEEETRME 415
            + +R+ E + E+  K E E   E
Sbjct: 301 RERQRERERERERNRKRERERERE 324



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 67/314 (21%), Positives = 100/314 (31%), Gaps = 45/314 (14%)

Query: 153 REMHRSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIFRE-EQ 211
           RE  R +  E + + R  + GR+       E    T   RK +  R      +  RE E+
Sbjct: 189 RERERQREKENKTEDRHSERGRERERERETE----TETERKRQTDRERDRQRKTEREREK 244

Query: 212 NGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRV 271
             E E    R     ++ ER R    D  R    RE    R+R     RDR+ ER   R 
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304

Query: 272 RSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEG 331
           R      + +R         + E E                       E+E + +   E 
Sbjct: 305 RERERERERNRK-------RERERE----------------------RERERERQRETER 335

Query: 332 EECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA 391
           +   + E     + +   + N++ G +  R      E   +    SAR     +      
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395

Query: 392 SQFER-----KDEPKTEQTEKAEEETRMENSLPAKVPSR------GDEMVADVQQPLSQI 440
            Q ER     KD     +TEK  E  +   S   +   R      G E   + Q      
Sbjct: 396 RQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAG 455

Query: 441 PSDTASPLLILPPP 454
                S L + PPP
Sbjct: 456 RQRKRSTLYVNPPP 469


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score =  106 bits (264), Expect = 2e-22
 Identities = 74/184 (40%), Positives = 109/184 (59%), Gaps = 15/184 (8%)

Query: 736 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 795
           +L+QE +E     +R++     QE+  R+QEE  R+   E +KR E+++  RR+ EE  R
Sbjct: 358 RLQQENKERSEALRRQQ---LLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR 414

Query: 796 RQREQEIALRRQREEEERQQQEEALRRLEE---RRREEEERRKQEELLRKQEEEAAKWAR 852
           R+RE     RRQ+E E+R++++E  RRLEE   RR+EEEERR+ EE  R+ E E     R
Sbjct: 415 REREA----RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRR 470

Query: 853 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQEALRRLQQ 911
           + EE QR LE  + ++ +E A L     E + +E+E  RQ E L RQ QQ+Q  L  LQ 
Sbjct: 471 QLEEEQRHLEVLQQQLLQEQAMLL----ECRWREMEEHRQAERLQRQLQQEQAYLLSLQH 526

Query: 912 QQQQ 915
             ++
Sbjct: 527 DHRR 530



 Score = 98.2 bits (243), Expect = 4e-20
 Identities = 71/220 (32%), Positives = 114/220 (51%), Gaps = 26/220 (11%)

Query: 729 LEKAKAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRRQ----QEEERK 778
           +++ +  + E++  E E     EEEE   ++E      +    E  LRR     Q+E ++
Sbjct: 306 IDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKE 365

Query: 779 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
           R E     +  QE+ LR Q E +  L  +R++   QQ+E+  R  E++RRE E RR+QE 
Sbjct: 366 RSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQER 425

Query: 839 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
             R++E+E  K   EE E +R+ EE R R EEE  R+  E+E  +R+  E QR  E+++Q
Sbjct: 426 EQRRREQE-EKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQ 484

Query: 899 RQQQQEAL---------------RRLQQQQQQQQLAQMKL 923
           +  Q++A+                RLQ+Q QQ+Q   + L
Sbjct: 485 QLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSL 524



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 57/305 (18%)

Query: 727  QQLEKAKAAKLEQERREAEMRAKRE-EEERKRQEELRRQQEEILRRQQEEERKRREEEE- 784
            +QL K    + +   R+  ++ K   +  RK++ E    + E    ++EEE    +E E 
Sbjct: 281  EQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEP 340

Query: 785  --LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 842
              +     E  LRR       LR Q+E +ER    EALRR  ++  +E++ R+QEE  R+
Sbjct: 341  SSIVNVPGESTLRRD-----FLRLQQENKERS---EALRR--QQLLQEQQLREQEEYKRQ 390

Query: 843  QEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ 902
               E  K   +++E +RRLEE + R  E  AR + E E+R+R++ E +R +EL R+R+++
Sbjct: 391  LLAERQKRIEQQKEQRRRLEEQQRR--EREARRQQEREQRRREQEEKRRLEELERRRKEE 448

Query: 903  QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE 962
            +E  RR ++++++                                 +++ +E   RQL E
Sbjct: 449  EER-RRAEEEKRR---------------------------------VEREQEYIRRQLEE 474

Query: 963  EQRRQQRELMKALQQQQQQQQQKL--SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
            EQR      ++ LQQQ  Q+Q  L    W  + +     +   ++QQE+A  +  Q   +
Sbjct: 475  EQRH-----LEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHR 529

Query: 1021 QQHQQ 1025
            + H Q
Sbjct: 530  RPHPQ 534



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 50/126 (39%), Positives = 83/126 (65%), Gaps = 4/126 (3%)

Query: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
           ++++Q ++ +    EQ+RRE E R ++E E+R+R++E +R+ EE+ RR++EEE +RR EE
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456

Query: 784 ELAR-RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 842
           E  R  +++E +RRQ E+E   +R  E  ++Q  +E    LE R RE EE R+ E L R+
Sbjct: 457 EKRRVEREQEYIRRQLEEE---QRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQ 513

Query: 843 QEEEAA 848
            ++E A
Sbjct: 514 LQQEQA 519



 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 61/191 (31%), Positives = 113/191 (59%), Gaps = 21/191 (10%)

Query: 722 ALEQLQQLEKAKAAKLEQERR----EAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777
           AL + Q L++ +  + E+ +R    E + R ++++E+R+R EE +R++ E  RRQQE E+
Sbjct: 369 ALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREA-RRQQEREQ 427

Query: 778 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 837
           +RRE+EE  +R+ EE  RR++E+E   RR+ EEE+R+ + E     E  RR+ EE ++  
Sbjct: 428 RRREQEE--KRRLEELERRRKEEEE--RRRAEEEKRRVEREQ----EYIRRQLEEEQRHL 479

Query: 838 ELLRKQ--EEEA----AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 891
           E+L++Q  +E+A     +W   E E  R+ E  + ++++E A L   + + +R   +  +
Sbjct: 480 EVLQQQLLQEQAMLLECRW--REMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQ 537

Query: 892 QKELMRQRQQQ 902
           Q    +Q + +
Sbjct: 538 QPPPPQQERSK 548


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score =  105 bits (263), Expect = 2e-22
 Identities = 76/307 (24%), Positives = 168/307 (54%), Gaps = 54/307 (17%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEER-----KRQEELRRQQEEILRRQQEEERK 778
            +QL QL++ K   +  +  + E++   ++++      + Q+ L++QQE++  +Q +E++ 
Sbjct: 128  QQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQV 187

Query: 779  RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
             +++E+L ++ QE+ L +Q+++++      ++++  QQ+E L++ + ++++E+ +++Q+ 
Sbjct: 188  LQQQEQLQQQVQEQQLLQQQQEQL------QQQQLLQQQEQLQQQQFQQQQEQLQQQQQL 241

Query: 839  LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
            LL +Q+ +  +   ++++AQ +             +L  +++ + +++L +Q+Q++L  Q
Sbjct: 242  LLLQQQGQLQQQLLQQQQAQLQ------------QQLLEQQQAQLQQQLLLQQQEQL--Q 287

Query: 899  RQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERER 958
            +QQQQ+ L++ Q+Q QQQQL    L               + +  L L  +    E+   
Sbjct: 288  QQQQQQLLQQQQEQLQQQQLQPPPLEPEE-----------EEEVELELMPVDLGSEQELE 336

Query: 959  QLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQ 1018
            Q R+E  RQQ      L++QQ+Q+Q +L             K   E+QQ E +  Q+QQQ
Sbjct: 337  QQRQELERQQE-----LERQQEQRQLQL-------------KLQEELQQLEQQLEQQQQQ 378

Query: 1019 QQQQHQQ 1025
             +QQ  Q
Sbjct: 379  LEQQEVQ 385



 Score =  105 bits (262), Expect = 3e-22
 Identities = 78/328 (23%), Positives = 175/328 (53%), Gaps = 43/328 (13%)

Query: 715  DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 774
            + T PG    QLQQLE+                 + E +++ + E+L++ Q  +  +QQ 
Sbjct: 80   EETRPGQRELQLQQLEQ-----------------QPEPQQQPQHEQLQQPQPHLELQQQP 122

Query: 775  EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 834
            ++  +++  +L + K +    ++ + E+ L  Q+++ + QQ +E  +RL++++ + + ++
Sbjct: 123  QQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQ-QRLQQQQEQLQTQQ 181

Query: 835  KQEELLRKQEEEAAKWAREEE---EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR 891
             QE+ + +Q+E+  +  +E++   + Q +L++ +L  ++E  +L+ ++ ++++++L+ Q+
Sbjct: 182  AQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE--QLQQQQFQQQQEQLQQQQ 239

Query: 892  QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK 951
            Q  L++Q+ Q Q+ L + QQ Q QQQL + +        Q       Q Q  L   + Q+
Sbjct: 240  QLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQ------AQLQQQLLLQQQEQLQQQQQQQ 293

Query: 952  LEEERERQLR-----------EEQRRQQRELMKA---LQQQQQQQQQKLSGWGNVSKPSG 997
            L ++++ QL+           EE+   + ELM      +Q+ +QQ+Q+L     + +   
Sbjct: 294  LLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQE 353

Query: 998  TTKSLLEIQQEEARQMQKQQQQQQQHQQ 1025
              +  L++Q+E  +  Q+ +QQQQQ +Q
Sbjct: 354  QRQLQLKLQEELQQLEQQLEQQQQQLEQ 381



 Score = 97.8 bits (242), Expect = 6e-20
 Identities = 100/414 (24%), Positives = 206/414 (49%), Gaps = 89/414 (21%)

Query: 591 PFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQ-QYAQVLAQQQKAALS 649
           P  P  + P    E+ +E    Q+EL    Q+Q L+ Q    QQ Q+ Q+   Q    L 
Sbjct: 64  PQRPAVSAPVGASEIAEETRPGQREL----QLQQLEQQPEPQQQPQHEQLQQPQPHLELQ 119

Query: 650 SQQQQQLALLLQQFQTLKMR-ISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGS 708
            Q QQ     L Q Q  K + +  Q + P               ELQ    Q        
Sbjct: 120 QQPQQDGQQQLSQLQQEKHQSVHHQELKP---------------ELQLMHQQ-------- 156

Query: 709 VWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQ--QE 766
                          +QLQ  +  +  +L+Q++ + + +  +E++  ++QE+L++Q  ++
Sbjct: 157 ---------------QQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQ 201

Query: 767 EILRRQQEEERKRR---EEEELARRK-QEEALRRQREQEIALRRQREEEERQQQEEALRR 822
           ++L++QQE+ ++++   ++E+L +++ Q++  + Q++Q++ L +Q+ + ++Q  ++   +
Sbjct: 202 QLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQ 261

Query: 823 LEERRREEEERRKQEELLRKQEEEAAKWAREE--EEAQRRLEENRLRM------EEEAAR 874
           L+++  E+++ + Q++LL +Q+E+  +  +++  ++ Q +L++ +L+       EEE   
Sbjct: 262 LQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVE 321

Query: 875 LR------HEEEERKRKELEVQRQKELMRQRQQQQ------EALRRLQQQ--QQQQQLAQ 920
           L         E+E +++  E++RQ+EL RQ++Q+Q      E L++L+QQ  QQQQQL Q
Sbjct: 322 LELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQ 381

Query: 921 MKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKA 974
            ++                 Q  L+  E+   ++E + +L   Q   Q EL+ A
Sbjct: 382 QEV-----------------QLELTPVELGAQQQEVQLELTPVQPELQLELVPA 418



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 85/320 (26%), Positives = 160/320 (50%), Gaps = 57/320 (17%)

Query: 715  DTTTPGPALEQLQQLEKAKAAKLEQERREAEM---RAKREEEERKRQEELRRQQEEILRR 771
            DT + G    + Q+ E+ +      +R         ++  EE R  Q EL+ QQ E    
Sbjct: 40   DTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLE---- 95

Query: 772  QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEE 831
            QQ E +++ + E+L + +    L++Q +Q+            QQQ   L++ + +    +
Sbjct: 96   QQPEPQQQPQHEQLQQPQPHLELQQQPQQD-----------GQQQLSQLQQEKHQSVHHQ 144

Query: 832  ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE--ERKRKELEV 889
            E + + +L+ +Q++   +  +E++  Q++ E+ + +  +E   L+ +E+  ++ +++  +
Sbjct: 145  ELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLL 204

Query: 890  QRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947
            Q+Q+E ++Q+Q  QQQE L++ Q QQQQ+QL Q           Q      Q Q  L   
Sbjct: 205  QQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQ-----------QQQLLLLQQQGQLQQQ 253

Query: 948  EIQKLEEERERQLREEQRRQ-QRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
             +Q+ + + ++QL E+Q+ Q Q++L+  LQQQ+Q QQQ                     Q
Sbjct: 254  LLQQQQAQLQQQLLEQQQAQLQQQLL--LQQQEQLQQQ---------------------Q 290

Query: 1007 QEEARQMQKQQQQQQQHQQP 1026
            Q++  Q Q++Q QQQQ Q P
Sbjct: 291  QQQLLQQQQEQLQQQQLQPP 310



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 69/284 (24%), Positives = 139/284 (48%), Gaps = 50/284 (17%)

Query: 763  RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR 822
            +++EE   R    +R        A    EE    QRE ++    Q+ E ++Q Q E L++
Sbjct: 52   QEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQ 111

Query: 823  ----LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE--EAARLR 876
                LE +++ +++ ++Q   L++++ ++      + E Q   ++ +L+ ++  E  RL+
Sbjct: 112  PQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQ 171

Query: 877  HEEEE---RKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQS 933
             ++E+   ++ +E +V +Q+E ++Q+ Q+Q+ L++ Q+Q QQQQL Q +           
Sbjct: 172  QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ----------- 220

Query: 934  NTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVS 993
                            ++L++++ +Q +E+ ++QQ+ L+  LQQQ Q QQQ L       
Sbjct: 221  ----------------EQLQQQQFQQQQEQLQQQQQLLL--LQQQGQLQQQLLQ------ 256

Query: 994  KPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNL 1037
                  +   ++QQ+   Q Q Q QQQ   QQ  + +      L
Sbjct: 257  ------QQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 104/490 (21%), Positives = 198/490 (40%), Gaps = 108/490 (22%)

Query: 311 KVQKEPIPEEQEMDFRPVDEGEECSD-----SEGSHNEEAKEPDKTNKKEGEKTDRVGVE 365
           +++  P  E   ++ + +++G    D     S GS ++E +EP + N           V 
Sbjct: 15  RMEVGPATETFVLELQCLEDGGPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVG 74

Query: 366 ASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSR 425
           ASE   +T     RPG     +  +  Q E++ EP+ +   +  ++ +    L  +    
Sbjct: 75  ASEIAEET-----RPG----QRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQD 125

Query: 426 GDEMVADVQQPLSQ-IPSDTASPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTEPDD 484
           G + ++ +QQ   Q +      P L L     +    L+P +                 +
Sbjct: 126 GQQQLSQLQQEKHQSVHHQELKPELQL----MHQQQQLQPQQV---------------QE 166

Query: 485 EEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEHRAKGVSIPLMHEAMQKWYYKDPQGE 544
           ++ L+  ++Q +   A  Q      E+L  ++QE +     +    E +Q+      Q +
Sbjct: 167 QQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQL----LQQQQEQLQQQQLLQQQEQ 222

Query: 545 IQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGE 604
           +Q     Q+                     E  Q    ++ +                G+
Sbjct: 223 LQQQQFQQQ--------------------QEQLQQQQQLLLL-------------QQQGQ 249

Query: 605 LDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQ 664
           L Q+ L +QQ   A  Q Q L+ QQ  +QQ   Q+L QQQ+     QQQQQ  LL QQ +
Sbjct: 250 LQQQLLQQQQ---AQLQQQLLEQQQAQLQQ---QLLLQQQE---QLQQQQQQQLLQQQQE 300

Query: 665 TLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE 724
            L+ +                       +LQP   +P   E   +  +P+D  +     +
Sbjct: 301 QLQQQ-----------------------QLQPPPLEPEEEEEVELELMPVDLGSEQELEQ 337

Query: 725 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEE 784
           Q Q+LE+ +  + +QE+R+ ++  K +EE ++ +++L +QQ+++   +Q+E +      E
Sbjct: 338 QRQELERQQELERQQEQRQLQL--KLQEELQQLEQQLEQQQQQL---EQQEVQLELTPVE 392

Query: 785 LARRKQEEAL 794
           L  ++QE  L
Sbjct: 393 LGAQQQEVQL 402



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 19/39 (48%), Positives = 28/39 (71%), Gaps = 4/39 (10%)

Query: 1197 KQKANQQRQQQQLPQQQQQQPPQQ----PPQQPQQQDSV 1231
            +Q+  QQ+QQQQL QQQQ+Q  QQ    PP +P++++ V
Sbjct: 282  QQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEV 320



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 66/339 (19%), Positives = 136/339 (40%), Gaps = 33/339 (9%)

Query: 959  QLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
            ++ EE R  QREL ++ L+QQ + QQQ         +P       LE+QQ    Q Q+  
Sbjct: 77   EIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPH------LELQQ----QPQQDG 126

Query: 1018 QQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMG 1077
            QQQ    Q  + ++  H  L   +   +       P        +        T+ +   
Sbjct: 127  QQQLSQLQQEKHQSVHHQELKPEL-QLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQ-- 183

Query: 1078 FWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQ 1137
                  + +  +    +      L +      +Q + ++++E+L +  Q   + Q+   Q
Sbjct: 184  ----EQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQ--QQFQQQQEQLQQ 237

Query: 1138 WCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRAK 1197
              +Q L  L     L         ++ +   ++ +  +A L      ++   Q  E+  +
Sbjct: 238  --QQQLLLLQQQGQLQQQLLQQ--QQAQLQQQLLEQQQAQL-----QQQLLLQQQEQLQQ 288

Query: 1198 QKANQ--QRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNF 1255
            Q+  Q  Q+QQ+QL QQQ Q PP +P ++ + +  +  ++  +   + Q  Q   +Q   
Sbjct: 289  QQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQEL 348

Query: 1256 EAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIE 1294
            E  Q  ++++ Q  ++ +   L   +    ++L   E++
Sbjct: 349  ERQQ--EQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQ 385


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score =  104 bits (260), Expect = 5e-22
 Identities = 81/327 (24%), Positives = 161/327 (49%), Gaps = 29/327 (8%)

Query: 723  LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR--- 779
            LE+ +  ++ +  ++E+ERRE E   +RE E R+R+ E  R++E    +++E ER+R   
Sbjct: 291  LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 350

Query: 780  ----------REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE 829
                      R+ E    R +E +  R +++  +  + R+ E  +++E    R  ER RE
Sbjct: 351  RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERE 410

Query: 830  EEERRKQEELLRKQEEEAAKWAREEEEA---QRRLEENRLRMEEEA--ARLRHEE--EER 882
             E  R++E    ++ E+  K  REE+E    +RR  E +LR +E A   RL++ E  E +
Sbjct: 411  REREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 470

Query: 883  KRKELEVQRQKELMRQRQQQQEALRR---LQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 939
            K +E E + ++E  R+R+  +EA R    L+     +   +    S+     +      +
Sbjct: 471  KTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEME 530

Query: 940  SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT 999
            +       E ++LEE R+R L E       EL +  Q+ ++++Q +      + +   + 
Sbjct: 531  ADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ------IKQEPESE 584

Query: 1000 KSLLEIQQEEARQMQKQQQQQQQHQQP 1026
            +   E Q++E ++ +  +++++  Q+P
Sbjct: 585  EEEEEKQEKEEKREEPMEEEEEPEQKP 611



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 76/308 (24%), Positives = 158/308 (51%), Gaps = 20/308 (6%)

Query: 727  QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR-RQQEEILRRQQEEERKRREEEEL 785
            ++LE+ K  K E+ER+E E   +  E ER+R+ E R R++E    R++E+E++R  E E 
Sbjct: 289  KKLEEEKGKK-EKERQEIEKERRERERERERERERREREREREREREREKEKERERERER 347

Query: 786  AR---RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE-EEERRKQEELLR 841
             R   R +E    R RE++    R+R  +  + +  +  +  +R RE E ER ++ E  R
Sbjct: 348  DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERER 407

Query: 842  KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKEL----MR 897
            ++E E  +    E E +R  ++ R R E+E       + ERK +E E   Q+ L    +R
Sbjct: 408  EREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 467

Query: 898  QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957
            +R++ +E  +  ++++++++    +      + +  +      +     A +QK   +RE
Sbjct: 468  ERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSA-LQKRLRDRE 526

Query: 958  RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
            +++  ++R ++RE     +++ ++ +Q+L   G+    +     L  ++QE  R+ Q Q 
Sbjct: 527  KEMEADERDRKRE-----KEELEEIRQRLLAEGHPDPDA----ELQRMEQEAERRRQPQI 577

Query: 1018 QQQQQHQQ 1025
            +Q+ + ++
Sbjct: 578  KQEPESEE 585



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 91/353 (25%), Positives = 150/353 (42%), Gaps = 71/353 (20%)

Query: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR---R 780
            E+ ++ EK K  + E+ER     R K  + +R R+ +  R +E    R ++  R R   R
Sbjct: 330  EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389

Query: 781  EEEELARRKQEEALRRQREQEIALRRQREEE-ERQQQEEALRRLEERRREEEERRKQEEL 839
            + E    R++E    R+RE+E    R+RE E ER+++++  R  EE   +  ERRK E  
Sbjct: 390  DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449

Query: 840  LRKQE----EEAAKW-------AREEEEAQRRLEENRLRMEEEAARLRH----------- 877
            LR++E    E    W        RE E+   R EE R  M +EA RL+            
Sbjct: 450  LREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD 509

Query: 878  ----------------------EEEERKRK--ELEVQRQKELMRQRQQQQEALRRLQQQQ 913
                                  +E +RKR+  ELE  RQ+ L          L+R++Q+ 
Sbjct: 510  PKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEA 569

Query: 914  QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK 973
            ++++  Q+K    S   ++               E Q+ EE+RE  + EE+  +Q+  +K
Sbjct: 570  ERRRQPQIKQEPESEEEEE---------------EKQEKEEKREEPMEEEEEPEQKPCLK 614

Query: 974  ALQQQQQQQQQKLSGWGNV--SKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQ 1024
               +         S  GN   + P   +   + I  E +      QQQ ++H+
Sbjct: 615  PTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENS----PDQQQPEEHR 663



 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 78/332 (23%), Positives = 159/332 (47%), Gaps = 53/332 (15%)

Query: 730  EKAKAAKLEQERREAEMRA---------KREEEERKRQEELRRQQEEILRRQQEEERKRR 780
            E   A ++E+++R+   R          K EEE+ K+++E +  ++E   R++E ER+R 
Sbjct: 262  EDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERE 321

Query: 781  EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
                  RR++E    R+RE+E    R+RE E  + ++    R  +R RE +  R +E   
Sbjct: 322  ------RREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSS 375

Query: 841  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR-KELEVQRQKELMRQR 899
             + ++ +   +RE+   + R  E     E E  R R  E ER+R +E E +R+K+  R R
Sbjct: 376  DRNKDRSR--SREKSRDREREREREREREREREREREREREREREREREREREKDKKRDR 433

Query: 900  QQQQE---ALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 956
            ++ +E     R+L+++ ++++ A  +   +    ++  T   + +A        + EEER
Sbjct: 434  EEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEA--------EREEER 485

Query: 957  ERQLREEQRRQQRELM--------------KALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1002
             R++ +E +R +  L                ALQ++ + +++++       K     + L
Sbjct: 486  RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKRE--KEEL 543

Query: 1003 LEIQQ--------EEARQMQKQQQQQQQHQQP 1026
             EI+Q        +   ++Q+ +Q+ ++ +QP
Sbjct: 544  EEIRQRLLAEGHPDPDAELQRMEQEAERRRQP 575



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 57/315 (18%), Positives = 152/315 (48%), Gaps = 49/315 (15%)

Query: 726  LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQ-------------QEEILRRQ 772
            ++ L +  +++L    +E++   +++++E+K  E++ R+             +E+I   +
Sbjct: 211  IEVLIREYSSELNAPSQESDSHPRKKKKEKK--EDIFRRFPVAPLIPYPLITKEDINAIE 268

Query: 773  QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE-- 830
             EE+++     E+++ +       + + +    RQ  E+ER+++E    R  ERR  E  
Sbjct: 269  MEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERE 328

Query: 831  ----EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 886
                 ER K++E  R++E +  +   +E +  R  E +R R  E ++    +    + K 
Sbjct: 329  REREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKS 388

Query: 887  LEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL 946
             + +R++E  R+R++++E  R  ++++++++  + +                        
Sbjct: 389  RDRERERERERERERERERERERERERERERERERE------------------------ 424

Query: 947  AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
               ++ +++R+R+  EE   ++R+L + L++++   Q++L  W  + +   T +   E +
Sbjct: 425  ---REKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNW-EIRERKKTREYEKEAE 480

Query: 1007 QEEARQMQKQQQQQQ 1021
            +EE R+ +  ++ ++
Sbjct: 481  REEERRREMAKEAKR 495



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 61/315 (19%), Positives = 142/315 (45%), Gaps = 60/315 (19%)

Query: 723  LEQLQQLEKAKAAKLEQERREA--EMRAKREEEE-RKRQEELRRQQEEILRRQQEEERKR 779
            L  LQ  EK    K++ + +    E +AK++      R E +    EE L    +EE KR
Sbjct: 147  LHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEAL----DEETKR 202

Query: 780  REE------EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER 833
            R++      E L R    E     +E +   R++++E++    E+  RR           
Sbjct: 203  RDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKK----EDIFRRFPVAPLIPYPL 258

Query: 834  RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK 893
              +E++   + EE  +     E ++ R  +   ++EEE  +     +E++R+E+E +R++
Sbjct: 259  ITKEDINAIEMEEDKRDLISREISKFR--DTHKKLEEEKGK-----KEKERQEIEKERRE 311

Query: 894  ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
               R+R++++E  RR ++++++++  + K                              E
Sbjct: 312  ---RERERERERERREREREREREREREK------------------------------E 338

Query: 954  EERERQL---REEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEA 1010
            +ERER+    R+  R ++R+  +  ++ + + +++ S        S       E ++E  
Sbjct: 339  KERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE 398

Query: 1011 RQMQKQQQQQQQHQQ 1025
            R+ +++++++++ ++
Sbjct: 399  RERERERERERERER 413



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 83/409 (20%), Positives = 141/409 (34%), Gaps = 57/409 (13%)

Query: 153 REMHRSQSWEERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQN 212
           RE  R +   ER +R  E+   K+  R    E       R  +  R++  +    RE   
Sbjct: 316 RERERERRERER-EREREREREKEKERERERE-------RDRDRDRTKERDRDRDRERDR 367

Query: 213 GEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVR 272
             D +   R +   +D  R R  S D  R        ER R  E + R+R+ ER   R R
Sbjct: 368 DRDRE---RSSDRNKDRSRSREKSRDRERERERERERERERERERE-RERERERERERER 423

Query: 273 SGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSL---------KKVQKEPIPEEQEM 323
                   DR+   E   E  + E    +   A+            KK ++     E+E 
Sbjct: 424 EREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREE 483

Query: 324 DFRP--VDEGEECSDSEGSHNEEAKEP-------------DKTNKKEGEKTDRVGV-EAS 367
           + R     E +   +    ++++  +P             D+  + E ++ DR    E  
Sbjct: 484 ERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEEL 543

Query: 368 EETPQTSSSSARPGTPSDHQSQEAS-------QFERKDEPKTEQTEKAEEETRMENSLPA 420
           EE  Q   +   P   ++ Q  E         Q +++ E + E+ EK E+E + E  +  
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEE 603

Query: 421 KVPSRGDEMVADVQQPLSQIPSDTA-------------SPLLILPPPVPNPSPTLRPVET 467
           +        +    +P+S  PS ++             SP  I+ P   +P         
Sbjct: 604 EEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEEHR 663

Query: 468 PVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKL 516
           P +G       S  P     +K  +   + +    +D   DD     KL
Sbjct: 664 PKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKL 712



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 54/217 (24%), Positives = 83/217 (38%), Gaps = 18/217 (8%)

Query: 209 EEQNGEDEDGGWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGY 268
           EE+ G+ E     +   RR+ ER R    +  R    RE    R R     ++R+ ER  
Sbjct: 292 EEEKGKKEKERQEIEKERRERERER----ERERERREREREREREREREKEKERERERER 347

Query: 269 RRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPV 328
            R R  +   D DRD   +    D + E  +  +     S +K +      E+E +    
Sbjct: 348 DRDRDRTKERDRDRDRERD---RDRDRERSSDRNKDRSRSREKSRDRERERERERERERE 404

Query: 329 DEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQS 388
            E E          E  +E ++  ++E EK  +   E  EE         R     +   
Sbjct: 405 RERER-------EREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAY 457

Query: 389 QE-ASQFERKDEPKTEQTEK---AEEETRMENSLPAK 421
           QE    +E ++  KT + EK    EEE R E +  AK
Sbjct: 458 QERLKNWEIRERKKTREYEKEAEREEERRREMAKEAK 494



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 83/390 (21%), Positives = 136/390 (34%), Gaps = 82/390 (21%)

Query: 118 RGRSSSRGRGRGRGECGFYQRSFD---EVEGVFGRGGGREMHRSQSWEERGDRRFEKPGR 174
           R RSS R + R R      ++S D   E E    R   RE  R +  E   +R  E+   
Sbjct: 371 RERSSDRNKDRSRSR----EKSRDRERERERERERERERERERERERERERERERERERE 426

Query: 175 KDVGRPNFEEGGPTSVGRKHEFIRSESE--------NWRIFREEQNGEDEDGGWRLAGSR 226
           KD  R   E+       RK E    E E        NW I   ++  E E    R    R
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486

Query: 227 RDGERWRPH----------SPDGPR----SAGWREHMERRRRFEFDFRDRDDERG----Y 268
           R+  +                D P+    SA  +   +R +  E D RDR  E+      
Sbjct: 487 REMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEI 546

Query: 269 RRVRSGSGSIDDDRDSLPEWCLEDAE--------EEMGTFDSSGAFLSLKKVQKEPIPEE 320
           R+     G  D D +   +   ++AE        +E  + +        ++ ++EP+ EE
Sbjct: 547 RQRLLAEGHPDPDAEL--QRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604

Query: 321 QEMD--------FRPVDEGEECSDSEGSHNEEAK------------EPDKTNKKEGEKTD 360
           +E +         RP+      S + G+                  E     ++  E   
Sbjct: 605 EEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEEHRP 664

Query: 361 RVGVE---ASEETPQTSSSSARPGTPSDH-----QSQEASQFERK-----------DEPK 401
           ++G+     +  +P   +S  R   P D      + +++    RK           D+  
Sbjct: 665 KIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVPLDYGEDDKNA 724

Query: 402 TEQTEKAEEETRMENSLPAKVPSRGDEMVA 431
           T+ T   EE+ +   SL  K+P+   E+ A
Sbjct: 725 TKGTVNTEEKRKHIKSLIEKIPTAKPELFA 754


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.126    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,280,989
Number of Sequences: 37866
Number of extensions: 3226170
Number of successful extensions: 141157
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1600
Number of HSP's successfully gapped in prelim test: 1505
Number of HSP's that attempted gapping in prelim test: 23371
Number of HSP's gapped (non-prelim): 37452
length of query: 1299
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1185
effective length of database: 13,930,794
effective search space: 16507990890
effective search space used: 16507990890
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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