Search of human proteins with 42476013

Search of human proteins with 42476013

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42476013 NHL repeat containing 2 [Homo sapiens]
         (726 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42476013 NHL repeat containing 2 [Homo sapiens]                   1470   0.0  
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]    37   0.050
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]    37   0.050
gi|32454739 tripartite motif-containing 3 [Homo sapiens]               37   0.065
gi|32454737 tripartite motif-containing 3 [Homo sapiens]               37   0.065
gi|84993742 tripartite motif-containing 71 [Homo sapiens]              36   0.14 
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H...    35   0.25 
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H...    35   0.25 
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H...    35   0.25 
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]                35   0.32 
gi|61744471 low density lipoprotein receptor-related protein 8 i...    33   0.71 
gi|61744467 low density lipoprotein receptor-related protein 8 i...    33   0.71 
gi|66082554 low density lipoprotein receptor-related protein 8 i...    33   0.71 
gi|65301119 low density lipoprotein receptor-related protein 8 i...    33   0.71 
gi|126012562 low density lipoprotein-related protein 1 [Homo sap...    32   1.6  
gi|55770832 cerebellar degeneration-related protein 2 [Homo sapi...    32   1.6  
gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]        32   2.1  
gi|157384998 low density lipoprotein receptor-related protein 4 ...    32   2.1  
gi|66529396 paraoxonase 2 isoform 2 [Homo sapiens]                     31   3.5  
gi|66529294 paraoxonase 2 isoform 1 [Homo sapiens]                     31   3.5  
gi|4557467 excision repair cross-complementing rodent repair def...    31   3.5  
gi|217416354 sphingosine kinase type 1-interacting protein isofo...    30   6.1  
gi|217416352 sphingosine kinase type 1-interacting protein isofo...    30   6.1  
gi|93102379 low density lipoprotein-related protein 1B precursor...    30   7.9  

>gi|42476013 NHL repeat containing 2 [Homo sapiens]
          Length = 726

 Score = 1470 bits (3806), Expect = 0.0
 Identities = 726/726 (100%), Positives = 726/726 (100%)

Query: 1   MAAPGGRGRSLSGLLPAQTSLEYALLDAVTQQEKDSLVYQYLQKVDGWEQDLSVPEFPEG 60
           MAAPGGRGRSLSGLLPAQTSLEYALLDAVTQQEKDSLVYQYLQKVDGWEQDLSVPEFPEG
Sbjct: 1   MAAPGGRGRSLSGLLPAQTSLEYALLDAVTQQEKDSLVYQYLQKVDGWEQDLSVPEFPEG 60

Query: 61  LEWLNTEEPISVYKDLCGKIVVLDFFTYCCINCIHLLPDLHALEHTYSDKDGLLIIGVHS 120
           LEWLNTEEPISVYKDLCGKIVVLDFFTYCCINCIHLLPDLHALEHTYSDKDGLLIIGVHS
Sbjct: 61  LEWLNTEEPISVYKDLCGKIVVLDFFTYCCINCIHLLPDLHALEHTYSDKDGLLIIGVHS 120

Query: 121 AKFPNEKVLDNIKSAVLRYNITHPMVNDADASLWQELEVSCWPTLVILGPRGNMLFSLIG 180
           AKFPNEKVLDNIKSAVLRYNITHPMVNDADASLWQELEVSCWPTLVILGPRGNMLFSLIG
Sbjct: 121 AKFPNEKVLDNIKSAVLRYNITHPMVNDADASLWQELEVSCWPTLVILGPRGNMLFSLIG 180

Query: 181 EGHKDKLFLYTSIALKYYKDRGQIRDNKIGIKLYKDSLPPSPLLFPGKVTVDQVTDRLVI 240
           EGHKDKLFLYTSIALKYYKDRGQIRDNKIGIKLYKDSLPPSPLLFPGKVTVDQVTDRLVI
Sbjct: 181 EGHKDKLFLYTSIALKYYKDRGQIRDNKIGIKLYKDSLPPSPLLFPGKVTVDQVTDRLVI 240

Query: 241 ADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTENHL 300
           ADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTENHL
Sbjct: 241 ADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTENHL 300

Query: 301 IRKIDLEAEKVSTVAGIGIQGTDKEGGAKGEQQPISSPWDVVFGTSGSEVQRGDILWIAM 360
           IRKIDLEAEKVSTVAGIGIQGTDKEGGAKGEQQPISSPWDVVFGTSGSEVQRGDILWIAM
Sbjct: 301 IRKIDLEAEKVSTVAGIGIQGTDKEGGAKGEQQPISSPWDVVFGTSGSEVQRGDILWIAM 360

Query: 361 AGTHQIWALLLDSGKLPKKNELTKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASE 420
           AGTHQIWALLLDSGKLPKKNELTKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASE
Sbjct: 361 AGTHQIWALLLDSGKLPKKNELTKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASE 420

Query: 421 DPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKLQHPLGV 480
           DPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKLQHPLGV
Sbjct: 421 DPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKLQHPLGV 480

Query: 481 TWDKKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNEPGGLCIG 540
           TWDKKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNEPGGLCIG
Sbjct: 481 TWDKKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNEPGGLCIG 540

Query: 541 ENGELLYVADTNNHQIKVMDLETKMVSVLPIFRSENAVVDGPFLVEKQKTLPKLPKSAPS 600
           ENGELLYVADTNNHQIKVMDLETKMVSVLPIFRSENAVVDGPFLVEKQKTLPKLPKSAPS
Sbjct: 541 ENGELLYVADTNNHQIKVMDLETKMVSVLPIFRSENAVVDGPFLVEKQKTLPKLPKSAPS 600

Query: 601 IRLSPVTACAGQTLQFKLRLDLPSGSKLTEGVSSCWFLTAEGNEWLLQGQIAAGDIENIS 660
           IRLSPVTACAGQTLQFKLRLDLPSGSKLTEGVSSCWFLTAEGNEWLLQGQIAAGDIENIS
Sbjct: 601 IRLSPVTACAGQTLQFKLRLDLPSGSKLTEGVSSCWFLTAEGNEWLLQGQIAAGDIENIS 660

Query: 661 SQPTISLQIPDDCLSLEAIVSVSVFLYYCSADSSACMMKAILFSQPLQITDTQQGCIAPV 720
           SQPTISLQIPDDCLSLEAIVSVSVFLYYCSADSSACMMKAILFSQPLQITDTQQGCIAPV
Sbjct: 661 SQPTISLQIPDDCLSLEAIVSVSVFLYYCSADSSACMMKAILFSQPLQITDTQQGCIAPV 720

Query: 721 ELRYVF 726
           ELRYVF
Sbjct: 721 ELRYVF 726


>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
          Length = 744

 Score = 37.4 bits (85), Expect = 0.050
 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 10/74 (13%)

Query: 487 NLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNEPGGLCIGENGELL 546
           N + + D +NH +KV + + +        G+ N           FN P G+ +  NG ++
Sbjct: 634 NEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGN---------GQFNAPTGVAVDSNGNII 684

Query: 547 YVADTNNHQIKVMD 560
            VAD  N +I+V D
Sbjct: 685 -VADWGNSRIQVFD 697



 Score = 30.4 bits (67), Expect = 6.1
 Identities = 23/97 (23%), Positives = 40/97 (41%), Gaps = 9/97 (9%)

Query: 214 YKDSLPPSPLLFPGKVTVDQVTDRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIF 273
           +K  +    L+ P  V+VD+    +++ D     + +   NG+I    G    G +    
Sbjct: 566 FKTKIGSGKLMGPKGVSVDR-NGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQ--- 621

Query: 274 SESTFNSPQGVAI-MNNIIYVADTENHLIRKIDLEAE 309
               F  P   A+  NN I + D  NH ++  + E E
Sbjct: 622 ----FAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGE 654


>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
          Length = 771

 Score = 37.4 bits (85), Expect = 0.050
 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 10/74 (13%)

Query: 487 NLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNEPGGLCIGENGELL 546
           N + + D +NH +KV + + +        G+ N           FN P G+ +  NG ++
Sbjct: 661 NEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGN---------GQFNAPTGVAVDSNGNII 711

Query: 547 YVADTNNHQIKVMD 560
            VAD  N +I+V D
Sbjct: 712 -VADWGNSRIQVFD 724



 Score = 30.4 bits (67), Expect = 6.1
 Identities = 23/97 (23%), Positives = 40/97 (41%), Gaps = 9/97 (9%)

Query: 214 YKDSLPPSPLLFPGKVTVDQVTDRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIF 273
           +K  +    L+ P  V+VD+    +++ D     + +   NG+I    G    G +    
Sbjct: 593 FKTKIGSGKLMGPKGVSVDR-NGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQ--- 648

Query: 274 SESTFNSPQGVAI-MNNIIYVADTENHLIRKIDLEAE 309
               F  P   A+  NN I + D  NH ++  + E E
Sbjct: 649 ----FAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGE 681


>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 37.0 bits (84), Expect = 0.065
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 10/84 (11%)

Query: 486 RNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNEPGGLCIGENGEL 545
           +N + V D +NH +KV     +        G+ N           FN P G+ +  NG +
Sbjct: 633 KNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGN---------GQFNAPTGVAVDSNGNI 683

Query: 546 LYVADTNNHQIKVMDLETKMVSVL 569
           + VAD  N +I+V D     +S +
Sbjct: 684 I-VADWGNSRIQVFDSSGSFLSYI 706



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 80/324 (24%), Positives = 119/324 (36%), Gaps = 87/324 (26%)

Query: 237 RLVIADTGHHRILVVWKNGQIQYSIG--GPNPGRKDGIFSESTFNSPQGVAI-MNNIIYV 293
           R+V+AD+ +  I V    GQ ++  G  G +PG+            P GVA+  N  I V
Sbjct: 499 RIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQ---------LQRPTGVAVDTNGDIIV 549

Query: 294 ADTENHLIRKIDLEAEKVSTVAGIGIQGTDKEGGAKGEQQPISSPWDVVFGTSGSEVQRG 353
           AD +N  +     E  K  T  G G                       + G  G  V R 
Sbjct: 550 ADYDNRWVSIFSPEG-KFKTKIGAG----------------------RLMGPKGVAVDRN 586

Query: 354 DILWIAMAGTHQIWALLLDSGKLPKKNELTKGTCLRFAGSGNEENRNNAYPHKAGFAQPS 413
             + +    +  ++     +GKL            RF G G   +R+ A PH        
Sbjct: 587 GHIIVVDNKSCCVFT-FQPNGKLVG----------RFGGRG-ATDRHFAGPH-------- 626

Query: 414 GLSLASEDPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAK 473
                        FVA +  + +      + +VK       D   LF FG   G G N +
Sbjct: 627 -------------FVAVNNKNEIVVTDFHNHSVKVY---SADGEFLFKFGS-HGEG-NGQ 668

Query: 474 LQHPLGVTWDKKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNE 533
              P GV  D   N++ VAD  N +I+V D           +G   +  ++S  E  +  
Sbjct: 669 FNAPTGVAVDSNGNII-VADWGNSRIQVFD----------SSGSFLSYINTS-AEPLYG- 715

Query: 534 PGGLCIGENGELLYVADTNNHQIK 557
           P GL +  +G ++ VAD  NH  K
Sbjct: 716 PQGLALTSDGHVV-VADAGNHCFK 738


>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 37.0 bits (84), Expect = 0.065
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 10/84 (11%)

Query: 486 RNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNEPGGLCIGENGEL 545
           +N + V D +NH +KV     +        G+ N           FN P G+ +  NG +
Sbjct: 633 KNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGN---------GQFNAPTGVAVDSNGNI 683

Query: 546 LYVADTNNHQIKVMDLETKMVSVL 569
           + VAD  N +I+V D     +S +
Sbjct: 684 I-VADWGNSRIQVFDSSGSFLSYI 706



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 80/324 (24%), Positives = 119/324 (36%), Gaps = 87/324 (26%)

Query: 237 RLVIADTGHHRILVVWKNGQIQYSIG--GPNPGRKDGIFSESTFNSPQGVAI-MNNIIYV 293
           R+V+AD+ +  I V    GQ ++  G  G +PG+            P GVA+  N  I V
Sbjct: 499 RIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQ---------LQRPTGVAVDTNGDIIV 549

Query: 294 ADTENHLIRKIDLEAEKVSTVAGIGIQGTDKEGGAKGEQQPISSPWDVVFGTSGSEVQRG 353
           AD +N  +     E  K  T  G G                       + G  G  V R 
Sbjct: 550 ADYDNRWVSIFSPEG-KFKTKIGAG----------------------RLMGPKGVAVDRN 586

Query: 354 DILWIAMAGTHQIWALLLDSGKLPKKNELTKGTCLRFAGSGNEENRNNAYPHKAGFAQPS 413
             + +    +  ++     +GKL            RF G G   +R+ A PH        
Sbjct: 587 GHIIVVDNKSCCVFT-FQPNGKLVG----------RFGGRG-ATDRHFAGPH-------- 626

Query: 414 GLSLASEDPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAK 473
                        FVA +  + +      + +VK       D   LF FG   G G N +
Sbjct: 627 -------------FVAVNNKNEIVVTDFHNHSVKVY---SADGEFLFKFGS-HGEG-NGQ 668

Query: 474 LQHPLGVTWDKKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNE 533
              P GV  D   N++ VAD  N +I+V D           +G   +  ++S  E  +  
Sbjct: 669 FNAPTGVAVDSNGNII-VADWGNSRIQVFD----------SSGSFLSYINTS-AEPLYG- 715

Query: 534 PGGLCIGENGELLYVADTNNHQIK 557
           P GL +  +G ++ VAD  NH  K
Sbjct: 716 PQGLALTSDGHVV-VADAGNHCFK 738


>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
          Length = 868

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 9/78 (11%)

Query: 226 PGKVTVDQVTDRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNSPQGVA 285
           P  V  D  + R+V+AD  +HRI +    GQ     G    G K+G      FN P  VA
Sbjct: 656 PAGVACD-ASRRIVVADKDNHRIQIFTFEGQFLLKFG--EKGTKNG-----QFNYPWDVA 707

Query: 286 I-MNNIIYVADTENHLIR 302
           +     I V+DT NH I+
Sbjct: 708 VNSEGKILVSDTRNHRIQ 725



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 11/86 (12%)

Query: 238 LVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNSPQGVAI-MNNIIYVADT 296
           LV+ D  +HR+LV+  + Q    +G    G          F  PQGVA+     I VAD+
Sbjct: 761 LVVTDFNNHRLLVIHPDCQSARFLGSEGTG-------NGQFLRPQGVAVDQEGRIIVADS 813

Query: 297 ENHLIRKIDLEAEKVSTVAGIGIQGT 322
            NH ++  +      S +   G QG+
Sbjct: 814 RNHRVQMFESNG---SFLCKFGAQGS 836



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 16/100 (16%)

Query: 463 GDVDGVGINAKLQHPLGVTWDKKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVT 522
           GD DG     KL  P GV+ DK+  ++ VAD  N++I+V  P         G       T
Sbjct: 600 GDSDG-----KLCRPWGVSVDKEGYII-VADRSNNRIQVFKP--------CGAFHHKFGT 645

Query: 523 SSSFTESTFNEPGGLCIGENGELLYVADTNNHQIKVMDLE 562
             S     F+ P G+    +  ++ VAD +NH+I++   E
Sbjct: 646 LGS-RPGQFDRPAGVACDASRRIV-VADKDNHRIQIFTFE 683



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 9/79 (11%)

Query: 224 LFPGKVTVDQVTDRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNSPQG 283
           L P  V VDQ   R+++AD+ +HR+ +   NG      G    G     F +   + P G
Sbjct: 795 LRPQGVAVDQ-EGRIIVADSRNHRVQMFESNGSFLCKFGAQGSG-----FGQ--MDRPSG 846

Query: 284 VAIM-NNIIYVADTENHLI 301
           +AI  + +I V D  N+ I
Sbjct: 847 IAITPDGMIVVVDFGNNRI 865


>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
           sapiens]
          Length = 589

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 7/113 (6%)

Query: 415 LSLASEDPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKL 474
           L + + +   C+      +STVR + L +   K +V G RD   L  +    G  ++  +
Sbjct: 325 LKVWNAETGECIHTLYGHTSTVRCMHLHE---KRVVSGSRDA-TLRVWDIETGQCLHVLM 380

Query: 475 QHPLGVTWDKKRNLLYVADSYNHKIKVVDPKTKNCT-TLAGTGDTNNVTSSSF 526
            H   V   +      V+ +Y+  +KV DP+T+ C  TL   G TN V S  F
Sbjct: 381 GHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL--QGHTNRVYSLQF 431


>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
           sapiens]
          Length = 707

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 7/113 (6%)

Query: 415 LSLASEDPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKL 474
           L + + +   C+      +STVR + L +   K +V G RD   L  +    G  ++  +
Sbjct: 443 LKVWNAETGECIHTLYGHTSTVRCMHLHE---KRVVSGSRDA-TLRVWDIETGQCLHVLM 498

Query: 475 QHPLGVTWDKKRNLLYVADSYNHKIKVVDPKTKNCT-TLAGTGDTNNVTSSSF 526
            H   V   +      V+ +Y+  +KV DP+T+ C  TL   G TN V S  F
Sbjct: 499 GHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL--QGHTNRVYSLQF 549


>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
           sapiens]
          Length = 627

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 7/113 (6%)

Query: 415 LSLASEDPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKL 474
           L + + +   C+      +STVR + L +   K +V G RD   L  +    G  ++  +
Sbjct: 363 LKVWNAETGECIHTLYGHTSTVRCMHLHE---KRVVSGSRDA-TLRVWDIETGQCLHVLM 418

Query: 475 QHPLGVTWDKKRNLLYVADSYNHKIKVVDPKTKNCT-TLAGTGDTNNVTSSSF 526
            H   V   +      V+ +Y+  +KV DP+T+ C  TL   G TN V S  F
Sbjct: 419 GHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTL--QGHTNRVYSLQF 469


>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
          Length = 2765

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 52/186 (27%), Positives = 76/186 (40%), Gaps = 32/186 (17%)

Query: 397  ENRNNAYPHKAGFAQPSGLSLASEDPWS-CLFVADSESSTVRTVSLKDGAVKHLVG---- 451
            E RN  + H    A    L++   DP S  L+V+D+ S  +  V    G  K L G    
Sbjct: 1264 ELRNKEFKHSNNPAHKYYLAV---DPVSGSLYVSDTNSRRIYRVKSLSGT-KDLAGNSEV 1319

Query: 452  ----GERD-PMNLFAFGDVDGVGINAKLQHPLGVTWDKKRNLLYVADSYNHKIKVVDPKT 506
                GE+  P +    GD  G  I+A L  P G+  D K  L+Y  D+    I+ VD + 
Sbjct: 1320 VAGTGEQCLPFDEARCGD-GGKAIDATLMSPRGIAVD-KNGLMYFVDA--TMIRKVD-QN 1374

Query: 507  KNCTTLAGTGDTNNV------TSSSFTESTFNEPGGLCIGENGELLYVADTN-------N 553
               +TL G+ D   V      +S    +     P  L +      LYV + N       N
Sbjct: 1375 GIISTLLGSNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITEN 1434

Query: 554  HQIKVM 559
            HQ+ ++
Sbjct: 1435 HQVSII 1440


>gi|61744471 low density lipoprotein receptor-related protein 8
           isoform 1 precursor [Homo sapiens]
          Length = 963

 Score = 33.5 bits (75), Expect = 0.71
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 12/107 (11%)

Query: 197 YYKDRG-QIRDNKIGIK-LYKDSLPPSPLLFPGKVTVDQVTDRLVIADTGHHRILVVWKN 254
           Y+ D G Q +  K G+  + + +L    + +P  +T+D ++ RL   D+  H++      
Sbjct: 555 YWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQL------ 608

Query: 255 GQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTENHLI 301
             I +S G     RK  I S    + P G+A+  + ++  D EN  I
Sbjct: 609 SSIDFSGGN----RKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAI 651


>gi|61744467 low density lipoprotein receptor-related protein 8
           isoform 3 precursor [Homo sapiens]
          Length = 700

 Score = 33.5 bits (75), Expect = 0.71
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 12/107 (11%)

Query: 197 YYKDRG-QIRDNKIGIK-LYKDSLPPSPLLFPGKVTVDQVTDRLVIADTGHHRILVVWKN 254
           Y+ D G Q +  K G+  + + +L    + +P  +T+D ++ RL   D+  H++      
Sbjct: 426 YWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQL------ 479

Query: 255 GQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTENHLI 301
             I +S G     RK  I S    + P G+A+  + ++  D EN  I
Sbjct: 480 SSIDFSGGN----RKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAI 522


>gi|66082554 low density lipoprotein receptor-related protein 8
           isoform 2 precursor [Homo sapiens]
          Length = 793

 Score = 33.5 bits (75), Expect = 0.71
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 12/107 (11%)

Query: 197 YYKDRG-QIRDNKIGIK-LYKDSLPPSPLLFPGKVTVDQVTDRLVIADTGHHRILVVWKN 254
           Y+ D G Q +  K G+  + + +L    + +P  +T+D ++ RL   D+  H++      
Sbjct: 385 YWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQL------ 438

Query: 255 GQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTENHLI 301
             I +S G     RK  I S    + P G+A+  + ++  D EN  I
Sbjct: 439 SSIDFSGGN----RKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAI 481


>gi|65301119 low density lipoprotein receptor-related protein 8
           isoform 4 precursor [Homo sapiens]
          Length = 904

 Score = 33.5 bits (75), Expect = 0.71
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 12/107 (11%)

Query: 197 YYKDRG-QIRDNKIGIK-LYKDSLPPSPLLFPGKVTVDQVTDRLVIADTGHHRILVVWKN 254
           Y+ D G Q +  K G+  + + +L    + +P  +T+D ++ RL   D+  H++      
Sbjct: 555 YWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQL------ 608

Query: 255 GQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTENHLI 301
             I +S G     RK  I S    + P G+A+  + ++  D EN  I
Sbjct: 609 SSIDFSGGN----RKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAI 651


>gi|126012562 low density lipoprotein-related protein 1 [Homo
           sapiens]
          Length = 4544

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 4/53 (7%)

Query: 464 DVDGVG----INAKLQHPLGVTWDKKRNLLYVADSYNHKIKVVDPKTKNCTTL 512
           D+DG      +++K+  P G+T D    L+Y AD+Y   I+VVD + K   T+
Sbjct: 352 DMDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTI 404


>gi|55770832 cerebellar degeneration-related protein 2 [Homo
           sapiens]
          Length = 454

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 17/114 (14%)

Query: 530 TFNEPGGLCIGENGEL-LYVADTNNHQIKVMDLETKMVSVLPIFRSENAVVDG------- 581
           T  E  GL + EN EL   +  T  ++ + ++LE ++  +  + +SE+  V+G       
Sbjct: 218 TMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPD 277

Query: 582 ----PFLVEKQKTLPKLPKSAPSIRLSPVTACAGQTLQFKLRLDLPSGSKLTEG 631
               PF    Q  L ++  + P     P+   + +T+   L     +GS + +G
Sbjct: 278 SLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSL-----AGSDIVKG 326


>gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]
          Length = 397

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 326 GGAKGEQQPISSPWDVVFGTS-GSEVQRGDILWIAMAGTHQIWALLLDSGKLPKKNELTK 384
           GG +   Q      +V FGT  GS+++  D LW+++   H    + + +  L  K+++++
Sbjct: 117 GGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISR 176

Query: 385 GTCLRFA 391
             C ++A
Sbjct: 177 EECDKYA 183


>gi|157384998 low density lipoprotein receptor-related protein 4 [Homo
            sapiens]
          Length = 1905

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 41/172 (23%), Positives = 74/172 (43%), Gaps = 37/172 (21%)

Query: 404  PHKAGFAQ--PSGLSLASE----DPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPM 457
            P+ +GF+   P+G++L S+     P    F+  +    +R VSL                
Sbjct: 1021 PNPSGFSCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSL---------------- 1064

Query: 458  NLFAFGDVDGVGINAKLQHPLGVTWDKKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGD 517
            ++  F DV  V IN  +++ + +  D +   +Y +DS  H+I        +   L G+  
Sbjct: 1065 DIPYFADVV-VPINITMKNTIAIGVDPQEGKVYWSDSTLHRI--------SRANLDGSQH 1115

Query: 518  TNNVTSSSFTESTFNEPGGLCIGENGELLYVADTNNHQIKVMDLETKMVSVL 569
             + +T+   T        GL +   G  +Y  DT  ++I+V +L+  M  VL
Sbjct: 1116 EDIITTGLQTTD------GLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVL 1161



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 27/127 (21%)

Query: 187  LFLYTSIALKYYKDRGQIRDNKIGIKLYKDSLPPSP--------LLFPGKVTVDQVTDRL 238
            + LY  +   Y+ D G+        KL +  +  S         L +P  +TVD+ + +L
Sbjct: 1172 IVLYHEMGFMYWTDWGE------NAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQL 1225

Query: 239  VIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTEN 298
            + AD    RI     NG  ++++  P                P G+ ++++ IY  D + 
Sbjct: 1226 LWADAHTERIEAADLNGANRHTLVSP-------------VQHPYGLTLLDSYIYWTDWQT 1272

Query: 299  HLIRKID 305
              I + D
Sbjct: 1273 RSIHRAD 1279


>gi|66529396 paraoxonase 2 isoform 2 [Homo sapiens]
          Length = 342

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 11/110 (10%)

Query: 479 GVTWDKKRNLLYVADSYNHKIKVVDPKTK-NCTTLAGTGDTNNVTSSSFTESTFNEPGGL 537
           G+        +YVAD   H+I V++  T  N T L        V + S   S+    G +
Sbjct: 212 GINISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSS----GDI 267

Query: 538 CIG--ENGELLYVADTNN----HQIKVMDLETKMVSVLPIFRSENAVVDG 581
            +G   NG+ L+V D NN      +++ ++ ++  +V  ++ +  +V+ G
Sbjct: 268 WVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQG 317


>gi|66529294 paraoxonase 2 isoform 1 [Homo sapiens]
          Length = 354

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 11/110 (10%)

Query: 479 GVTWDKKRNLLYVADSYNHKIKVVDPKTK-NCTTLAGTGDTNNVTSSSFTESTFNEPGGL 537
           G+        +YVAD   H+I V++  T  N T L        V + S   S+    G +
Sbjct: 224 GINISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSS----GDI 279

Query: 538 CIG--ENGELLYVADTNN----HQIKVMDLETKMVSVLPIFRSENAVVDG 581
            +G   NG+ L+V D NN      +++ ++ ++  +V  ++ +  +V+ G
Sbjct: 280 WVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQG 329


>gi|4557467 excision repair cross-complementing rodent repair
           deficiency, complementation group 8 isoform 1 [Homo
           sapiens]
          Length = 396

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 29/133 (21%), Positives = 49/133 (36%), Gaps = 26/133 (19%)

Query: 425 CLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKLQHPLGVTWDK 484
           CL    +    V+   LK G+  H++ G R                    Q  L V+W  
Sbjct: 157 CLVAVGTRGPKVQLCDLKSGSCSHILQGHR--------------------QEILAVSWSP 196

Query: 485 KRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTEST----FNEPGGLCIG 540
           + + +    S + ++K+ D +  +   +  T D +N   S   ES       +  GLC  
Sbjct: 197 RYDYILATASADSRVKLWDVRRASGCLI--TLDQHNGKKSQAVESANTAHNGKVNGLCFT 254

Query: 541 ENGELLYVADTNN 553
            +G  L    T+N
Sbjct: 255 SDGLHLLTVGTDN 267


>gi|217416354 sphingosine kinase type 1-interacting protein isoform 1
            [Homo sapiens]
          Length = 1700

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 4/97 (4%)

Query: 536  GLCIGENGELLYVADTNNHQIKVMDLETKMVSVLPIFRSENAVVDGPFLVEKQKTLPKLP 595
            GLC  ++   LY     +H   ++  ET   S+  + R    +VD     + +      P
Sbjct: 1284 GLC--KSDSCLYRRGGTDHITNMLIHETWASSIEALMRKNKIIVDDAEEADTEPVSGGSP 1341

Query: 596  KSAPSI--RLSPVTACAGQTLQFKLRLDLPSGSKLTE 630
              A     RL+    C+G TL  +  LD P    +TE
Sbjct: 1342 SQAEKCANRLAASRMCSGPTLLVQESLDCPRKDSVTE 1378


>gi|217416352 sphingosine kinase type 1-interacting protein isoform 2
            [Homo sapiens]
          Length = 1671

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 4/97 (4%)

Query: 536  GLCIGENGELLYVADTNNHQIKVMDLETKMVSVLPIFRSENAVVDGPFLVEKQKTLPKLP 595
            GLC  ++   LY     +H   ++  ET   S+  + R    +VD     + +      P
Sbjct: 1284 GLC--KSDSCLYRRGGTDHITNMLIHETWASSIEALMRKNKIIVDDAEEADTEPVSGGSP 1341

Query: 596  KSAPSI--RLSPVTACAGQTLQFKLRLDLPSGSKLTE 630
              A     RL+    C+G TL  +  LD P    +TE
Sbjct: 1342 SQAEKCANRLAASRMCSGPTLLVQESLDCPRKDSVTE 1378


>gi|93102379 low density lipoprotein-related protein 1B precursor
           [Homo sapiens]
          Length = 4599

 Score = 30.0 bits (66), Expect = 7.9
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 11/92 (11%)

Query: 221 SPLLFPGKVTVDQVTDRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNS 280
           S +L+P  +T+D  T+ L   D  +  I  V+ NG             +  ++S    N 
Sbjct: 692 SKMLWPNGLTLDFHTNTLYWCDAYYDHIEKVFLNGT-----------HRKIVYSGRELNH 740

Query: 281 PQGVAIMNNIIYVADTENHLIRKIDLEAEKVS 312
           P G++   N ++  D  N  I ++DL   +V+
Sbjct: 741 PFGLSHHGNYVFWTDYMNGSIFQLDLITSEVT 772


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,083,621
Number of Sequences: 37866
Number of extensions: 1355393
Number of successful extensions: 3052
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 3005
Number of HSP's gapped (non-prelim): 59
length of query: 726
length of database: 18,247,518
effective HSP length: 110
effective length of query: 616
effective length of database: 14,082,258
effective search space: 8674670928
effective search space used: 8674670928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.