Guide to the Human Genome
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Search of human proteins with 42476009

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42476009 highly divergent homeobox [Homo sapiens]
         (690 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42476009 highly divergent homeobox [Homo sapiens]                 1381   0.0  
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    50   9e-06
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    50   9e-06
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    50   9e-06
gi|42476164 POU class 2 homeobox 1 [Homo sapiens]                      43   0.001
gi|223890225 POU class 6 homeobox 1 [Homo sapiens]                     38   0.027
gi|122937345 myosin VB [Homo sapiens]                                  38   0.027
gi|7662260 kelch repeat and BTB (POZ) domain containing 11 [Homo...    38   0.036
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         37   0.047
gi|148664218 POU transcription factor [Homo sapiens]                   37   0.061
gi|56961680 coiled-coil domain containing 147 [Homo sapiens]           36   0.10 
gi|195976779 dysferlin isoform 1 [Homo sapiens]                        36   0.14 
gi|195976773 dysferlin isoform 5 [Homo sapiens]                        36   0.14 
gi|195976769 dysferlin isoform 6 [Homo sapiens]                        36   0.14 
gi|195976764 dysferlin isoform 14 [Homo sapiens]                       36   0.14 
gi|195976758 dysferlin isoform 11 [Homo sapiens]                       36   0.14 
gi|195976756 dysferlin isoform 10 [Homo sapiens]                       36   0.14 
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 36   0.14 
gi|170784824 paired box 4 [Homo sapiens]                               36   0.14 
gi|148613886 regulatory factor X domain containing 2 [Homo sapiens]    36   0.14 
gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens]       35   0.23 
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    35   0.23 
gi|215982794 myosin VA isoform 2 [Homo sapiens]                        35   0.30 
gi|55770834 centromere protein F [Homo sapiens]                        35   0.30 
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]            35   0.30 
gi|221219020 NYD-SP11 protein [Homo sapiens]                           34   0.40 
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    34   0.52 
gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Hom...    34   0.52 
gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Hom...    34   0.52 
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    34   0.52 

>gi|42476009 highly divergent homeobox [Homo sapiens]
          Length = 690

 Score = 1381 bits (3574), Expect = 0.0
 Identities = 690/690 (100%), Positives = 690/690 (100%)

Query: 1   MNLRSVFTVEQQRILQRYYENGMTNQSKNCFQLILQCAQETKLDFSVVRTWVGNKRRKMS 60
           MNLRSVFTVEQQRILQRYYENGMTNQSKNCFQLILQCAQETKLDFSVVRTWVGNKRRKMS
Sbjct: 1   MNLRSVFTVEQQRILQRYYENGMTNQSKNCFQLILQCAQETKLDFSVVRTWVGNKRRKMS 60

Query: 61  SKNSESGTATTGTSLSAPDITVRNVVNIARPSSQQSSWTSANNDVIVTGIYSPASSSSRQ 120
           SKNSESGTATTGTSLSAPDITVRNVVNIARPSSQQSSWTSANNDVIVTGIYSPASSSSRQ
Sbjct: 61  SKNSESGTATTGTSLSAPDITVRNVVNIARPSSQQSSWTSANNDVIVTGIYSPASSSSRQ 120

Query: 121 GTNKHTDTQITEAHKIPIQKTATKNDTEFQLHIPVQRQVAHCKNASLLLGEKTIILSRQT 180
           GTNKHTDTQITEAHKIPIQKTATKNDTEFQLHIPVQRQVAHCKNASLLLGEKTIILSRQT
Sbjct: 121 GTNKHTDTQITEAHKIPIQKTATKNDTEFQLHIPVQRQVAHCKNASLLLGEKTIILSRQT 180

Query: 181 SVLNAGNSVFNHAKKNYGNSSVQASEMTVPQKPSVCHRPCKIEPVGIQRSYKPEHTGPAL 240
           SVLNAGNSVFNHAKKNYGNSSVQASEMTVPQKPSVCHRPCKIEPVGIQRSYKPEHTGPAL
Sbjct: 181 SVLNAGNSVFNHAKKNYGNSSVQASEMTVPQKPSVCHRPCKIEPVGIQRSYKPEHTGPAL 240

Query: 241 HNLCGQKPTIRDPYCRTQNLEIREVFSLAVSDYPQRILGGNAPQKPSSAEGNCLSIAMET 300
           HNLCGQKPTIRDPYCRTQNLEIREVFSLAVSDYPQRILGGNAPQKPSSAEGNCLSIAMET
Sbjct: 241 HNLCGQKPTIRDPYCRTQNLEIREVFSLAVSDYPQRILGGNAPQKPSSAEGNCLSIAMET 300

Query: 301 GDAEDEYAREEELASMRAQIPSYSRFYESGSSLRAENQSTTLPGPGRNMPNSQMVNIRDM 360
           GDAEDEYAREEELASMRAQIPSYSRFYESGSSLRAENQSTTLPGPGRNMPNSQMVNIRDM
Sbjct: 301 GDAEDEYAREEELASMRAQIPSYSRFYESGSSLRAENQSTTLPGPGRNMPNSQMVNIRDM 360

Query: 361 SDNVLYQNRNYHLTPRTSLHTASSTMYSNTNPLRSNFSPHFASSNQLRLSQNQNNYQISG 420
           SDNVLYQNRNYHLTPRTSLHTASSTMYSNTNPLRSNFSPHFASSNQLRLSQNQNNYQISG
Sbjct: 361 SDNVLYQNRNYHLTPRTSLHTASSTMYSNTNPLRSNFSPHFASSNQLRLSQNQNNYQISG 420

Query: 421 NLTVPWITGCSRKRALQDRTQFSDRDLATLKKYWDNGMTSLGSVCREKIEAVATELNVDC 480
           NLTVPWITGCSRKRALQDRTQFSDRDLATLKKYWDNGMTSLGSVCREKIEAVATELNVDC
Sbjct: 421 NLTVPWITGCSRKRALQDRTQFSDRDLATLKKYWDNGMTSLGSVCREKIEAVATELNVDC 480

Query: 481 EIVRTWIGNRRRKYRLMGIEVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRN 540
           EIVRTWIGNRRRKYRLMGIEVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRN
Sbjct: 481 EIVRTWIGNRRRKYRLMGIEVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRN 540

Query: 541 DEVSICLSEGSSQEEPNEVVPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQ 600
           DEVSICLSEGSSQEEPNEVVPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQ
Sbjct: 541 DEVSICLSEGSSQEEPNEVVPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQ 600

Query: 601 VNSFLDYKNEEVKFIENELEIQKQKYFKLQTFVRSLILAMKADDKEQQQALLSDLPPELE 660
           VNSFLDYKNEEVKFIENELEIQKQKYFKLQTFVRSLILAMKADDKEQQQALLSDLPPELE
Sbjct: 601 VNSFLDYKNEEVKFIENELEIQKQKYFKLQTFVRSLILAMKADDKEQQQALLSDLPPELE 660

Query: 661 EMDFNHASLEPDDTSFSVSSLSEKNVSESL 690
           EMDFNHASLEPDDTSFSVSSLSEKNVSESL
Sbjct: 661 EMDFNHASLEPDDTSFSVSSLSEKNVSESL 690


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 12/193 (6%)

Query: 504  PRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPN---EVV 560
            P   PAD S  PE+ +       EE  P V E+  +++E    L E   +EE +   E  
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETA 1309

Query: 561  PNDAR-AHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFLD----YKNEEVKFI 615
             ND   A  E+D H  +T   ++E     E D+     V++  SFLD       E++K  
Sbjct: 1310 QNDDHDADDEDDGHLESTKKKELEEQPTRE-DVKEEPGVQE--SFLDANMQKSREKIKDK 1366

Query: 616  ENELEIQKQKYFKLQTFVRSLILAMKADDKEQQQALLSDLPPELEEMDFNHASLEPDDTS 675
            E      +++     T V S  +A   DD E+      +L    EE +  H+ L+  +T 
Sbjct: 1367 EETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDL-ETV 1425

Query: 676  FSVSSLSEKNVSE 688
             +V SL+++  SE
Sbjct: 1426 QAVQSLTQEESSE 1438


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 12/193 (6%)

Query: 504  PRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPN---EVV 560
            P   PAD S  PE+ +       EE  P V E+  +++E    L E   +EE +   E  
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETA 1309

Query: 561  PNDAR-AHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFLD----YKNEEVKFI 615
             ND   A  E+D H  +T   ++E     E D+     V++  SFLD       E++K  
Sbjct: 1310 QNDDHDADDEDDGHLESTKKKELEEQPTRE-DVKEEPGVQE--SFLDANMQKSREKIKDK 1366

Query: 616  ENELEIQKQKYFKLQTFVRSLILAMKADDKEQQQALLSDLPPELEEMDFNHASLEPDDTS 675
            E      +++     T V S  +A   DD E+      +L    EE +  H+ L+  +T 
Sbjct: 1367 EETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDL-ETV 1425

Query: 676  FSVSSLSEKNVSE 688
             +V SL+++  SE
Sbjct: 1426 QAVQSLTQEESSE 1438


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 12/193 (6%)

Query: 504  PRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPN---EVV 560
            P   PAD S  PE+ +       EE  P V E+  +++E    L E   +EE +   E  
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETA 1309

Query: 561  PNDAR-AHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFLD----YKNEEVKFI 615
             ND   A  E+D H  +T   ++E     E D+     V++  SFLD       E++K  
Sbjct: 1310 QNDDHDADDEDDGHLESTKKKELEEQPTRE-DVKEEPGVQE--SFLDANMQKSREKIKDK 1366

Query: 616  ENELEIQKQKYFKLQTFVRSLILAMKADDKEQQQALLSDLPPELEEMDFNHASLEPDDTS 675
            E      +++     T V S  +A   DD E+      +L    EE +  H+ L+  +T 
Sbjct: 1367 EETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDL-ETV 1425

Query: 676  FSVSSLSEKNVSE 688
             +V SL+++  SE
Sbjct: 1426 QAVQSLTQEESSE 1438


>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
          Length = 743

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 33/107 (30%), Positives = 53/107 (49%), Gaps = 12/107 (11%)

Query: 422 LTVPWITGCSRKRALQDRTQFSDRDLATLKKYWDNGMTSLGSVCREKIEAVATELNVDCE 481
           L  P I G SR+R  +   + + R +A  K + +N   +      E+I  +A +LN++ E
Sbjct: 368 LNSPGIEGLSRRRKKRTSIETNIR-VALEKSFLENQKPT-----SEEITMIADQLNMEKE 421

Query: 482 IVRTWIGNRRRKYRLMGIEVPPPRGGPADFSEQ---PESGSLSALTP 525
           ++R W  NRR+K + +    PP  GG +    +   P   SL A TP
Sbjct: 422 VIRVWFCNRRQKEKRIN---PPSSGGTSSSPIKAIFPSPTSLVATTP 465


>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
          Length = 301

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 6/62 (9%)

Query: 431 SRKRALQDRTQFSDRDLATLKKYWDNGMTSLGSVCREKIEAVATELNVDCEIVRTWIGNR 490
           S+KR  + RT F+ + +  L  Y++      G    ++I  +A ELN D E+VR W  NR
Sbjct: 232 SKKR--KRRTSFTPQAIEALNAYFEKNPLPTG----QEITEIAKELNYDREVVRVWFCNR 285

Query: 491 RR 492
           R+
Sbjct: 286 RQ 287


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 36/151 (23%), Positives = 66/151 (43%), Gaps = 17/151 (11%)

Query: 553  QEEPNEVVPNDARAHKE----EDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFL--- 605
            QEE   +     RAH E    ED H+   D ++  + D E+ + +   E EQ+N+ +   
Sbjct: 982  QEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQ 1041

Query: 606  ---DYKNEEVK--FIENELEIQKQKYFKLQTFVRSLI-LAMKADDKEQQQALLSDLPPEL 659
               ++    VK   ++ ELE ++ +Y   Q  V+    L  + D+   +  ++   P   
Sbjct: 1042 SKDEFAQNSVKENLMKKELEEERSRY---QNLVKEYSQLEQRYDNLRDEMTIIKQTPGHR 1098

Query: 660  EEMDFNHASLEPDDTSFSVSSLSEKNVSESL 690
                 N +SLE D    S+S+    +  ++L
Sbjct: 1099 RNPS-NQSSLESDSNYPSISTSEIGDTEDAL 1128


>gi|7662260 kelch repeat and BTB (POZ) domain containing 11 [Homo
           sapiens]
          Length = 623

 Score = 37.7 bits (86), Expect = 0.036
 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 502 PPPRGGPADFSEQPESGSLSALTPGEEAGPE----VGEDNDRNDEVSICLSEGSSQEEPN 557
           PP  GGP     Q E+GS  A +P E A PE      E    + E  + L + +S EEP 
Sbjct: 65  PPSSGGPRVVERQWEAGSAGAASPEELASPEERACPEEPAAPSPEPRVWLEDPASPEEPG 124

Query: 558 EVVP 561
           E  P
Sbjct: 125 EPAP 128


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 37.4 bits (85), Expect = 0.047
 Identities = 19/64 (29%), Positives = 39/64 (60%)

Query: 55  KRRKMSSKNSESGTATTGTSLSAPDITVRNVVNIARPSSQQSSWTSANNDVIVTGIYSPA 114
           +RR +S   S SG++ +G+S  +  ++V +V +++  +S  SS  S +++ +   + SP 
Sbjct: 680 RRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPV 739

Query: 115 SSSS 118
           SS+S
Sbjct: 740 SSAS 743


>gi|148664218 POU transcription factor [Homo sapiens]
          Length = 436

 Score = 37.0 bits (84), Expect = 0.061
 Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 7/93 (7%)

Query: 434 RALQDRTQFSDRDLATL-KKYWDNGMTSLGSVCREKIEAVATELNVDCEIVRTWIGNRRR 492
           R  + RT        TL K++ DN   S      E+I  +A +L+++ E+VR W  NRR+
Sbjct: 280 RKRKKRTSIETNIRLTLEKRFQDNPKPS-----SEEISMIAEQLSMEKEVVRVWFCNRRQ 334

Query: 493 KYRLMGIEVPPPRGGPADFSE-QPESGSLSALT 524
           K + +   V  P   P   S     SGSL  L+
Sbjct: 335 KEKRINCPVATPIKPPVYNSRLVSPSGSLGPLS 367


>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
          Length = 872

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 34/166 (20%), Positives = 73/166 (43%), Gaps = 22/166 (13%)

Query: 532 EVGEDNDRNDEVSICLSEGSSQEEPNEVVPNDARAHKEEDHHAVTTDNVKIEIIDDEESD 591
           EV ++ D+     + L E  +Q    +    +    KEE  HA++    +I+   +E S 
Sbjct: 157 EVTKERDQLLSEVVKLRESLAQTTEQQ---QETERSKEEAEHAISQFQQEIQQRQNEASR 213

Query: 592 MISNSE-----VEQVNSFLDYKNEEVKFIENELEIQKQKYFKLQTFVRSLILAMKADDKE 646
                E     ++Q+ + +D +  E+K ++  ++  K++  KL+               +
Sbjct: 214 EFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLE------------QQLK 261

Query: 647 QQQALLSDLPPELEEMDFNHASLEPDDTSFSV--SSLSEKNVSESL 690
           +Q+ L      ELE+    +A L+ ++   S+    LS++N  ++L
Sbjct: 262 EQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKAL 307


>gi|195976779 dysferlin isoform 1 [Homo sapiens]
          Length = 2119

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 25/121 (20%)

Query: 500  EVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPNEV 559
            E P P+GGP D         +S L+PGE+   ++   +D+   + I L++G S   P   
Sbjct: 1454 ESPSPQGGPDD---------VSLLSPGEDVLIDI---DDKEPLIPIQLADGLSSLAPTNT 1501

Query: 560  VPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFLDYKNEEVKFIENEL 619
                +  H+E             E ID       S  E E+  S+L+   + +K  + +L
Sbjct: 1502 ASPPSSPHEE-------------EFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQL 1548

Query: 620  E 620
            E
Sbjct: 1549 E 1549


>gi|195976773 dysferlin isoform 5 [Homo sapiens]
          Length = 2088

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 25/121 (20%)

Query: 500  EVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPNEV 559
            E P P+GGP D         +S L+PGE+   ++   +D+   + I L++G S   P   
Sbjct: 1423 ESPSPQGGPDD---------VSLLSPGEDVLIDI---DDKEPLIPIQLADGLSSLAPTNT 1470

Query: 560  VPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFLDYKNEEVKFIENEL 619
                +  H+E             E ID       S  E E+  S+L+   + +K  + +L
Sbjct: 1471 ASPPSSPHEE-------------EFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQL 1517

Query: 620  E 620
            E
Sbjct: 1518 E 1518


>gi|195976769 dysferlin isoform 6 [Homo sapiens]
          Length = 2102

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 25/121 (20%)

Query: 500  EVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPNEV 559
            E P P+GGP D         +S L+PGE+   ++   +D+   + I L++G S   P   
Sbjct: 1437 ESPSPQGGPDD---------VSLLSPGEDVLIDI---DDKEPLIPIQLADGLSSLAPTNT 1484

Query: 560  VPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFLDYKNEEVKFIENEL 619
                +  H+E             E ID       S  E E+  S+L+   + +K  + +L
Sbjct: 1485 ASPPSSPHEE-------------EFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQL 1531

Query: 620  E 620
            E
Sbjct: 1532 E 1532


>gi|195976764 dysferlin isoform 14 [Homo sapiens]
          Length = 2118

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 25/121 (20%)

Query: 500  EVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPNEV 559
            E P P+GGP D         +S L+PGE+   ++   +D+   + I L++G S   P   
Sbjct: 1453 ESPSPQGGPDD---------VSLLSPGEDVLIDI---DDKEPLIPIQLADGLSSLAPTNT 1500

Query: 560  VPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFLDYKNEEVKFIENEL 619
                +  H+E             E ID       S  E E+  S+L+   + +K  + +L
Sbjct: 1501 ASPPSSPHEE-------------EFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQL 1547

Query: 620  E 620
            E
Sbjct: 1548 E 1548


>gi|195976758 dysferlin isoform 11 [Homo sapiens]
          Length = 2101

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 25/121 (20%)

Query: 500  EVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPNEV 559
            E P P+GGP D         +S L+PGE+   ++   +D+   + I L++G S   P   
Sbjct: 1436 ESPSPQGGPDD---------VSLLSPGEDVLIDI---DDKEPLIPIQLADGLSSLAPTNT 1483

Query: 560  VPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFLDYKNEEVKFIENEL 619
                +  H+E             E ID       S  E E+  S+L+   + +K  + +L
Sbjct: 1484 ASPPSSPHEE-------------EFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQL 1530

Query: 620  E 620
            E
Sbjct: 1531 E 1531


>gi|195976756 dysferlin isoform 10 [Homo sapiens]
          Length = 2087

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 25/121 (20%)

Query: 500  EVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPNEV 559
            E P P+GGP D         +S L+PGE+   ++   +D+   + I L++G S   P   
Sbjct: 1422 ESPSPQGGPDD---------VSLLSPGEDVLIDI---DDKEPLIPIQLADGLSSLAPTNT 1469

Query: 560  VPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFLDYKNEEVKFIENEL 619
                +  H+E             E ID       S  E E+  S+L+   + +K  + +L
Sbjct: 1470 ASPPSSPHEE-------------EFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQL 1516

Query: 620  E 620
            E
Sbjct: 1517 E 1517


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 23/80 (28%), Positives = 48/80 (60%), Gaps = 4/80 (5%)

Query: 578  DNVKIEIIDDEESDMIS-NSEVEQVNSFLDYKNEEVKFIENELEIQKQKYFKL-QTFVRS 635
            +N+K+++ ++ E ++    +EVE +   LD   +E + +++EL+ QK+   +   T +R+
Sbjct: 1666 ENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRN 1725

Query: 636  LILAMKAD--DKEQQQALLS 653
            L+  +K+    KE+QQ  LS
Sbjct: 1726 LVERLKSQLALKEKQQKALS 1745


>gi|170784824 paired box 4 [Homo sapiens]
          Length = 343

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 35/109 (32%), Positives = 44/109 (40%), Gaps = 18/109 (16%)

Query: 437 QDRTQFSDRDLATLKKYWDNGMTSLGSVCREKIEAVATELNVDCEIVRTWIGNRRRKYR- 495
           ++RT FS      L+K +  G     SV R K+ A AT L  D   VR W  NRR K+R 
Sbjct: 164 RNRTIFSPSQAEALEKEFQRGQYP-DSVARGKL-ATATSLPEDT--VRVWFSNRRAKWRR 219

Query: 496 -------------LMGIEVPPPRGGPADFSEQPESGSLSALTPGEEAGP 531
                          G+ VP    G     + P S   +AL   E  GP
Sbjct: 220 QEKLKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGP 268


>gi|148613886 regulatory factor X domain containing 2 [Homo sapiens]
          Length = 1460

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 14/193 (7%)

Query: 61  SKNSESGTATTGTSLSAPDITVRNVVNIARPSSQQSSWTSANNDVIVTGIYSPASSSSRQ 120
           S +  S T TT  S S P I   +VV++  P S+ S   SA     V     P +SS   
Sbjct: 492 SASVSSATGTTEESRSVPQIKNGSVVSLQSPGSRSS---SAGGTSAVEVKVEPETSSDEH 548

Query: 121 GTNKHTDTQITEAHKIPIQKTATKNDTEFQLHIPVQRQVAHCKNASLLLGEKTIILSRQT 180
                 ++   +A + P      K++T+  L  P    V   K A+ +  ++T   SR  
Sbjct: 549 PVQCQENSDEAKAPQTPSALLGQKSNTDGALQKPSNEGVIEIK-ATKVCDQRTKCKSRCN 607

Query: 181 SVL-------NAGNSVFNHAKKN--YGNSSVQASEMTVPQKPSVCHR-PCKIEPVGIQRS 230
            +L       N      + A +N  + +SS   +  ++ + P +C + P K     +Q +
Sbjct: 608 EMLPGTSTGNNQSTITLSVASQNLTFTSSSSPPNGDSINKDPKLCTKSPRKRLSSTLQET 667

Query: 231 YKPEHTGPALHNL 243
             P    P +  L
Sbjct: 668 QVPPVKKPIVEQL 680


>gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens]
          Length = 637

 Score = 35.0 bits (79), Expect = 0.23
 Identities = 24/75 (32%), Positives = 32/75 (42%)

Query: 496 LMGIEVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEE 555
           L G   PPP  G A  +    SG+     P E +  E       N  VS+ LSE   +  
Sbjct: 90  LRGPAAPPPPAGGAANNHGAGSGAGGRAAPVESSQEEQSLCEGSNSAVSMELSEPIVENG 149

Query: 556 PNEVVPNDARAHKEE 570
             E+ P ++  HKEE
Sbjct: 150 ETEMSPEESWEHKEE 164


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 35.0 bits (79), Expect = 0.23
 Identities = 31/103 (30%), Positives = 42/103 (40%), Gaps = 17/103 (16%)

Query: 498 GIEVPPPRGGPADFSEQPESGSLSALTPGEEAGPE-VGEDNDRNDEVSICLSEGSSQEEP 556
           G EV     G +   E+PES    A  P +E GP+ V E +D             S EE 
Sbjct: 268 GQEVDYMSDGSSSSQEEPES---KAKAPQQEEGPKGVDEQSD-------------SSEES 311

Query: 557 NEVVPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVE 599
            E  P +    +EE+  A T    K      EESD    S+++
Sbjct: 312 EEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDID 354


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 36/129 (27%), Positives = 60/129 (46%), Gaps = 19/129 (14%)

Query: 533  VGEDND-RNDEVSICLSEGSSQEEPNEVVPNDARAHKEEDHHAVTTDNVKIEIIDDEESD 591
            V E+ D R +EV I  S+  SQ+E   + P D       D + +T   + +E +      
Sbjct: 1255 VSEELDVRKEEVLILRSQLVSQKEA--IQPKD-------DKNTMTDSTILLEDVQK---- 1301

Query: 592  MISNSEVEQVNSFLDYKNEEVKFIENELEIQKQKYFKLQTFVRSLILAMKADDKEQQQAL 651
            M    E+ Q    L   N   + +E++L+ QK+ +      +R  I ++K ++  QQQ L
Sbjct: 1302 MKDKGEIAQAYIGLKETN---RLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLL 1358

Query: 652  LSD--LPPE 658
              +  LPPE
Sbjct: 1359 AQNLQLPPE 1367


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 34/164 (20%), Positives = 72/164 (43%), Gaps = 23/164 (14%)

Query: 549 EGSSQEEPNEVVPNDARAHKEEDHHAVTTDNVKIEIIDDEES-----DMISNSE--VEQV 601
           E  ++    E +  D +    +  +++T + +K+ + D E+      D++   E  +EQ+
Sbjct: 525 EMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQL 584

Query: 602 NSFLDYKNEEVKFIENELEIQKQKY---------FKLQTFVRSLILAMKADDKEQQQALL 652
           N  L    +E K + + LE++K++Y         F         +L     +KE  Q+ +
Sbjct: 585 NDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKI 644

Query: 653 SDL-----PPELEEMDFNH--ASLEPDDTSFSVSSLSEKNVSES 689
           + L       +++  ++N    +LE D  + SV   +  NV +S
Sbjct: 645 NHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDS 688


>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
          Length = 1444

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 27/115 (23%), Positives = 44/115 (38%), Gaps = 6/115 (5%)

Query: 449  TLKKYWDNGMTSLGSVCREKIEAVATELNVDC--EIVRTWIGNRRRKYR----LMGIEVP 502
            T+K  W   + S  S    + E  +  L        +  W     R +R    L G E P
Sbjct: 960  TVKSQWTLEVPSSSSCANLETERNSDPLQPQAPRREITGWDEKALRSFREFSGLKGAEAP 1019

Query: 503  PPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPN 557
            P + GP+     P   S  +L  G+E G  +G  + +  +  +   E S +  P+
Sbjct: 1020 PNQKGPSGVQPNPAETSPISLAEGKELGTHLGHSSPQIRQGGVPGPESSKESSPS 1074


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 34.3 bits (77), Expect = 0.40
 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 18/133 (13%)

Query: 511  FSEQPES--------GSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPNEVVPN 562
            FSE+ ES         SLS+    E    E  E+ +  +E      E   +E+  E    
Sbjct: 2226 FSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEE 2285

Query: 563  DARAHKEEDHHAVTTDNVKI-----EIIDDEESDMISNSEVEQVNSFLDYKNEEVKFIEN 617
            + +  K+E       +  ++     EI+ +EE++ +S+ E E+ +  L+ + +  K I  
Sbjct: 2286 EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEI-- 2343

Query: 618  ELEIQKQKYFKLQ 630
               ++K+K FKLQ
Sbjct: 2344 ---LKKEKQFKLQ 2353


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 33.9 bits (76), Expect = 0.52
 Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 8/87 (9%)

Query: 557  NEVVPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEV-------EQVNSFLDYKN 609
            NE+     +  KE+     T   +++ +  D +   + N E+       +++N  L  KN
Sbjct: 1122 NELEELQVQLQKEKKQLQKTMQELEL-VKKDAQQTTLMNMEIADYERLMKELNQKLTNKN 1180

Query: 610  EEVKFIENELEIQKQKYFKLQTFVRSL 636
             +++ +E E++IQKQK   LQ  + SL
Sbjct: 1181 NKIEDLEQEIKIQKQKQETLQEEITSL 1207



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 1/91 (1%)

Query: 599 EQVNSFLDYKNEEVKFIENELEIQKQKYFKLQTFVRSLILAMKADDKEQQQALLSDLPPE 658
           +Q+++  D K E V  ++N +E   Q Y K    ++  +L +KA  +E+ + L+  +   
Sbjct: 203 KQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEAS 262

Query: 659 LEEMDFNHASL-EPDDTSFSVSSLSEKNVSE 688
            +E +     L E  +        SEKN+ +
Sbjct: 263 AKEHEAEINKLNELKENLVKQCEASEKNIQK 293


>gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Homo
           sapiens]
          Length = 823

 Score = 33.9 bits (76), Expect = 0.52
 Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 6/87 (6%)

Query: 74  SLSAPDIT-VRNVVNIARP-SSQQSSWTSANNDVIVTGIYSPASSSSRQGTNKHTDTQIT 131
           SLS PD+     +    RP S  QSS+TS  + +   GI+  +SSSS + + +  D    
Sbjct: 49  SLSVPDLLEAEALAPEGRPYSGPQSSYTSVPSSLSTAGIFPKSSSSSLKQSEEELDWSQE 108

Query: 132 EAHKIPIQKTATKNDTEFQLHIPVQRQ 158
           EA  + + +T    D+E     P +R+
Sbjct: 109 EASHLHVVET----DSEEAYASPAERR 131


>gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Homo
           sapiens]
          Length = 878

 Score = 33.9 bits (76), Expect = 0.52
 Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 6/87 (6%)

Query: 74  SLSAPDIT-VRNVVNIARP-SSQQSSWTSANNDVIVTGIYSPASSSSRQGTNKHTDTQIT 131
           SLS PD+     +    RP S  QSS+TS  + +   GI+  +SSSS + + +  D    
Sbjct: 49  SLSVPDLLEAEALAPEGRPYSGPQSSYTSVPSSLSTAGIFPKSSSSSLKQSEEELDWSQE 108

Query: 132 EAHKIPIQKTATKNDTEFQLHIPVQRQ 158
           EA  + + +T    D+E     P +R+
Sbjct: 109 EASHLHVVET----DSEEAYASPAERR 131


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 33.9 bits (76), Expect = 0.52
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 238 PALHNLCGQKPTIRDPYCRTQNLEIREVFSLAVSDYPQRILGGNAPQKPSSA-EGNCLSI 296
           PA     G + +  D    +   E  +    AV   PQ++ GG AP KP+SA +G   S 
Sbjct: 458 PAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESS 517

Query: 297 AMETGD--AEDEYAREEELASMRAQIPSYSRFYESGSSLRAEN 337
              + D  +E+E  + +   S R Q P  +      S+L A+N
Sbjct: 518 NSSSSDDSSEEEEEKLKGKGSPRPQAPKAN----GTSALTAQN 556


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.126    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,802,555
Number of Sequences: 37866
Number of extensions: 1268034
Number of successful extensions: 4445
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 109
Number of HSP's that attempted gapping in prelim test: 4300
Number of HSP's gapped (non-prelim): 266
length of query: 690
length of database: 18,247,518
effective HSP length: 109
effective length of query: 581
effective length of database: 14,120,124
effective search space: 8203792044
effective search space used: 8203792044
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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