Search of human proteins with 41152107

Search of human proteins with 41152107

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41152107 ubiquitin-like 7 [Homo sapiens]
         (380 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41152107 ubiquitin-like 7 [Homo sapiens]                           752   0.0  
gi|14249682 ubiquitin-like 7 [Homo sapiens]                           752   0.0  
gi|16753207 ubiquilin 2 [Homo sapiens]                                 52   9e-07
gi|40538799 ataxin-1 ubiquitin-like interacting protein [Homo sa...    52   9e-07
gi|16753205 ubiquilin 1 isoform 2 [Homo sapiens]                       50   3e-06
gi|16753203 ubiquilin 1 isoform 1 [Homo sapiens]                       50   3e-06
gi|8567418 ubiquilin 3 [Homo sapiens]                                  43   5e-04
gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]    43   5e-04
gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]    43   5e-04
gi|67906195 ankyrin repeat and sterile alpha motif domain contai...    42   0.001
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...    41   0.002
gi|5032187 transducer of ERBB2, 1 [Homo sapiens]                       40   0.005
gi|54607108 zinc finger, MIZ-type containing 2 isoform 1 [Homo s...    40   0.005
gi|115334682 SNAP25-interacting protein [Homo sapiens]                 40   0.005
gi|54607110 zinc finger, MIZ-type containing 2 isoform 2 [Homo s...    40   0.005
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom...    39   0.008
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom...    39   0.008
gi|91982772 mucin 17 [Homo sapiens]                                    38   0.013
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             38   0.017
gi|24497609 nucleoporin 62kDa [Homo sapiens]                           37   0.023
gi|24497607 nucleoporin 62kDa [Homo sapiens]                           37   0.023
gi|24497605 nucleoporin 62kDa [Homo sapiens]                           37   0.023
gi|24497603 nucleoporin 62kDa [Homo sapiens]                           37   0.023
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s...    37   0.038
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ...    37   0.038
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ...    37   0.038
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s...    37   0.038
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    36   0.050
gi|11415052 retinoid X receptor, beta [Homo sapiens]                   36   0.050
gi|67010025 Sp4 transcription factor [Homo sapiens]                    36   0.066

>gi|41152107 ubiquitin-like 7 [Homo sapiens]
          Length = 380

 Score =  752 bits (1941), Expect = 0.0
 Identities = 380/380 (100%), Positives = 380/380 (100%)

Query: 1   MSLSDWHLAVKLADQPLTPKSILRLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPEL 60
           MSLSDWHLAVKLADQPLTPKSILRLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPEL
Sbjct: 1   MSLSDWHLAVKLADQPLTPKSILRLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPEL 60

Query: 61  IDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAAMREFRVLHTAL 120
           IDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAAMREFRVLHTAL
Sbjct: 61  IDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAAMREFRVLHTAL 120

Query: 121 HSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVP 180
           HSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVP
Sbjct: 121 HSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVP 180

Query: 181 AHPALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNT 240
           AHPALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNT
Sbjct: 181 AHPALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNT 240

Query: 241 RSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGT 300
           RSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGT
Sbjct: 241 RSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGT 300

Query: 301 SPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRAL 360
           SPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRAL
Sbjct: 301 SPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRAL 360

Query: 361 QATGGDIQAALELIFAGGAP 380
           QATGGDIQAALELIFAGGAP
Sbjct: 361 QATGGDIQAALELIFAGGAP 380


>gi|14249682 ubiquitin-like 7 [Homo sapiens]
          Length = 380

 Score =  752 bits (1941), Expect = 0.0
 Identities = 380/380 (100%), Positives = 380/380 (100%)

Query: 1   MSLSDWHLAVKLADQPLTPKSILRLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPEL 60
           MSLSDWHLAVKLADQPLTPKSILRLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPEL
Sbjct: 1   MSLSDWHLAVKLADQPLTPKSILRLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPEL 60

Query: 61  IDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAAMREFRVLHTAL 120
           IDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAAMREFRVLHTAL
Sbjct: 61  IDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAAMREFRVLHTAL 120

Query: 121 HSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVP 180
           HSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVP
Sbjct: 121 HSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVP 180

Query: 181 AHPALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNT 240
           AHPALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNT
Sbjct: 181 AHPALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNT 240

Query: 241 RSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGT 300
           RSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGT
Sbjct: 241 RSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGT 300

Query: 301 SPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRAL 360
           SPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRAL
Sbjct: 301 SPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRAL 360

Query: 361 QATGGDIQAALELIFAGGAP 380
           QATGGDIQAALELIFAGGAP
Sbjct: 361 QATGGDIQAALELIFAGGAP 380


>gi|16753207 ubiquilin 2 [Homo sapiens]
          Length = 624

 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 38/96 (39%), Positives = 50/96 (52%), Gaps = 9/96 (9%)

Query: 280 STPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQS--- 336
           ST       PT  +   S  TSP S   +SG    N  F Q +  AL  +  P L +   
Sbjct: 527 STGSGGPTGPTVSSAAPSETTSPTS---ESGP---NQQFIQQMVQALAGANAPQLPNPEV 580

Query: 337 QWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALE 372
           ++Q QL+QL  MG  + E +L+AL ATGGDI AA+E
Sbjct: 581 RFQQQLEQLNAMGFLNREANLQALIATGGDINAAIE 616



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 69/345 (20%), Positives = 124/345 (35%), Gaps = 52/345 (15%)

Query: 39  SISFLKQLIAGKLQESVPDPELIDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPD 98
           S+   K+ I+ + +      + + LI+ G+ LKD  TL  +GI  G TVH++ KS   P 
Sbjct: 53  SVQQFKEAISKRFKSQT---DQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQ 109

Query: 99  QKPEPVDKVAAMREFRVLHTALHSS--------------------SSYREAVFKMLSNKE 138
            +       A            +S+                    SS   +       + 
Sbjct: 110 GQSTQPSNAAGTNTTSASTPRSNSTPISTNSNPFGLGSLGGLAGLSSLGLSSTNFSELQS 169

Query: 139 SLDQIIVATP----GLSSDPIALGVLQDKDLFS--VFADPNMLDTLVPAHPALVNA---- 188
            + Q ++A+P     +  +P    +L + DL    + A+P M   L+  +P + +     
Sbjct: 170 QMQQQLMASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQM-QQLIQRNPEISHLLNNP 228

Query: 189 -IVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGF-LFEGLSDDEDDFHPNTRSTPSS 246
            I+     +A +  M      ++ +  S+   +PGG+     +  D  +   N       
Sbjct: 229 DIMRQTLEIARNPAMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFG 288

Query: 247 STPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSG 306
             P +   S   SG       T++           P  +   P P TQ  ++ ++  S+G
Sbjct: 289 GNPFASVGSSSSSGEGTQPSRTENR---------DPLPNPWAPPPATQSSATTSTTTSTG 339

Query: 307 VQSGTPITNDLFS--QALQHALQASGQPSLQSQWQ-----PQLQQ 344
             SG   +N   +   A  +       P +QS  Q     PQL Q
Sbjct: 340 SGSGNSSSNATGNTVAAANYVASIFSTPGMQSLLQQITENPQLIQ 384


>gi|40538799 ataxin-1 ubiquitin-like interacting protein [Homo
           sapiens]
          Length = 601

 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 37/100 (37%), Positives = 53/100 (53%), Gaps = 15/100 (15%)

Query: 286 SHTPTPGTQGHSSGTSPMSSGVQSGTPITND----------LFSQALQHALQASGQPSLQ 335
           S TP P   G ++G++P +      TP T+           L  Q +Q  L  SG   +Q
Sbjct: 496 SRTPAPSA-GSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQMIQ-LLAGSGNSQVQ 553

Query: 336 S---QWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALE 372
           +   ++Q QL+QL  MG  + E +L+AL ATGGDI AA+E
Sbjct: 554 TPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIE 593



 Score = 35.4 bits (80), Expect = 0.086
 Identities = 18/39 (46%), Positives = 27/39 (69%), Gaps = 1/39 (2%)

Query: 63  LIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKP 101
           LI+ G+ LKD  TL+ +GI+ G TVH++ K+ P+  Q P
Sbjct: 54  LIFAGKILKDGDTLNQHGIKDGLTVHLVIKT-PQKAQDP 91



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 2/68 (2%)

Query: 240 TRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGT-QGHSS 298
           T S+PS+  P+S P++   S A   +P T S  A++ A + +  SS   P+PG  +G  S
Sbjct: 95  TASSPSTPDPASAPSTTPASPATPAQPST-SGSASSDAGSGSRRSSGGGPSPGAGEGSPS 153

Query: 299 GTSPMSSG 306
            T+ + SG
Sbjct: 154 ATASILSG 161


>gi|16753205 ubiquilin 1 isoform 2 [Homo sapiens]
          Length = 561

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 10/99 (10%)

Query: 277 ALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQS 336
           AL ST  SS      GT G ++  S  +S     T   +  F Q +  AL A   P LQ+
Sbjct: 462 ALGSTGGSS------GTNGSNATPSENTSPTAGTTEPGHQQFIQQMLQAL-AGVNPQLQN 514

Query: 337 ---QWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALE 372
              ++Q QL+QL  MG  + E +L+AL ATGGDI AA+E
Sbjct: 515 PEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIE 553



 Score = 37.4 bits (85), Expect = 0.023
 Identities = 74/365 (20%), Positives = 140/365 (38%), Gaps = 58/365 (15%)

Query: 63  LIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEP-DQKPEPVDKVAAMREFRVLHTALH 121
           LI+ G+ LKD  TL  +GI  G TVH++ K+   P D   +  +   +         +  
Sbjct: 78  LIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNTAGSNVTTSSTPNSNS 137

Query: 122 SSSSYREAVFKM--LSNKESLDQIIVATPG------------LSSDPIALGVLQDKDLFS 167
           +S S     F +  L     L  + + T              LS+  + + ++++  + S
Sbjct: 138 TSGSATSNPFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQS 197

Query: 168 VFADPNMLDTLVPAHPALVNAIVL---VLH------------SVAGSAPMPGTDSSSRSM 212
           + ++P+++  L+ A+P +   I     + H             +A +  M      ++  
Sbjct: 198 MLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDR 257

Query: 213 PSSSYRDMPGGF-----LFEG-----LSDDEDDFHPNTRSTPSSSTPSSRPASLGYSGAA 262
             S+   +PGG+     ++       LS  ++ F  N  ++  S+T S   +    +   
Sbjct: 258 ALSNLESIPGGYNALRRMYTDIQEPMLSAAQEQFGGNPFASLVSNTSSGEGSQPSRTENR 317

Query: 263 GP-----RPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQS---GTPIT 314
            P      P T    + +   AST   ++ +   GT G S+    +  GV +    TP  
Sbjct: 318 DPLPNPWAPQTSQSSSASSGTASTVGGTTGSTASGTSGQSTTAPNLVPGVGASMFNTPGM 377

Query: 315 NDLFS------QALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRALQATGGDIQ 368
             L        Q +Q+ L A   P ++S  Q  L Q  D+  Q       +  +    +Q
Sbjct: 378 QSLLQQITENPQLMQNMLSA---PYMRSMMQ-SLSQNPDLAAQMQNPDTLSAMSNPRAMQ 433

Query: 369 AALEL 373
           A L++
Sbjct: 434 ALLQI 438


>gi|16753203 ubiquilin 1 isoform 1 [Homo sapiens]
          Length = 589

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 10/99 (10%)

Query: 277 ALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQS 336
           AL ST  SS      GT G ++  S  +S     T   +  F Q +  AL A   P LQ+
Sbjct: 490 ALGSTGGSS------GTNGSNATPSENTSPTAGTTEPGHQQFIQQMLQAL-AGVNPQLQN 542

Query: 337 ---QWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALE 372
              ++Q QL+QL  MG  + E +L+AL ATGGDI AA+E
Sbjct: 543 PEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIE 581



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 58/289 (20%), Positives = 115/289 (39%), Gaps = 47/289 (16%)

Query: 63  LIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEP-DQKPEPVDKVAAMREFRVLHTALH 121
           LI+ G+ LKD  TL  +GI  G TVH++ K+   P D   +  +   +         +  
Sbjct: 78  LIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNTAGSNVTTSSTPNSNS 137

Query: 122 SSSSYREAVFKM--LSNKESLDQIIVATPG------------LSSDPIALGVLQDKDLFS 167
           +S S     F +  L     L  + + T              LS+  + + ++++  + S
Sbjct: 138 TSGSATSNPFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQS 197

Query: 168 VFADPNMLDTLVPAHPALVNAIVL---VLH------------SVAGSAPMPGTDSSSRSM 212
           + ++P+++  L+ A+P +   I     + H             +A +  M      ++  
Sbjct: 198 MLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDR 257

Query: 213 PSSSYRDMPGGF-----LFEG-----LSDDEDDFHPNTRSTPSSSTPSSRPASLGYSGAA 262
             S+   +PGG+     ++       LS  ++ F  N  ++  S+T S         G+ 
Sbjct: 258 ALSNLESIPGGYNALRRMYTDIQEPMLSAAQEQFGGNPFASLVSNTSSG-------EGSQ 310

Query: 263 GPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGT 311
             R   +  L    A  ++  SS+ + T  T G ++G++   +  QS T
Sbjct: 311 PSRTENRDPLPNPWAPQTSQSSSASSGTASTVGGTTGSTASGTSGQSTT 359


>gi|8567418 ubiquilin 3 [Homo sapiens]
          Length = 655

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 20/38 (52%), Positives = 29/38 (76%)

Query: 335 QSQWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALE 372
           ++ +Q QL+QLR MG  + E +L+AL ATGGD+ AA+E
Sbjct: 613 EAHFQVQLEQLRSMGFLNREANLQALIATGGDVDAAVE 650



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 14/35 (40%), Positives = 23/35 (65%)

Query: 58 PELIDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRK 92
          P+ + LI+ G+ LKD  +L   G++ G TVH++ K
Sbjct: 58 PDQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIK 92


>gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]
          Length = 922

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 20/179 (11%)

Query: 146 ATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIVLVLHSVAGSAPMPGT 205
           ATP  ++ P+           +  +  N+L+T++P  P  V++ V   H+   S P P T
Sbjct: 258 ATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAV---HTPQPSIPNP-T 313

Query: 206 DSSSRSMPSS------SYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRP---ASL 256
              + S+P++      S    P   +F GL        P   +TP+++TP+  P   ++L
Sbjct: 314 VIRTPSLPTAPVTSIHSTTTTPVPSIFSGLVS-----LPGPSATPTAATPTPGPTPRSTL 368

Query: 257 GYSGA--AGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPI 313
           G S A  +   P T    +T+ + AST   +S + +    G      P S G+ + TP+
Sbjct: 369 GSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSNPTPV 427



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 46/173 (26%), Positives = 66/173 (38%), Gaps = 24/173 (13%)

Query: 191 LVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTP------ 244
           L L +   SA  P    +  ++P+      PG  LF GL         N+ STP      
Sbjct: 481 LTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGLALFPGLPSPV----ANSTSTPLTLPVQ 536

Query: 245 -----SSSTPSSRPASLGYSGA--AGPRPITQSELATALALASTPESSSHTPTPGTQGHS 297
                ++S  +S P S G S +   GP P T       L ++STP +++      T+  S
Sbjct: 537 SPLATAASASTSVPVSCGSSASLLRGPHPGTSD-----LHISSTPAATTLPVMIKTEPTS 591

Query: 298 SGTSPMSSGVQSGTPITNDL-FSQALQHALQASGQP-SLQSQWQPQLQQLRDM 348
              S       SG P    L  S  L  A  ++  P SL +   P L  L  +
Sbjct: 592 PTPSAFKGPSHSGNPSHGTLGLSGTLGRAYTSTSVPISLSACLNPALSGLSSL 644


>gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]
          Length = 944

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 20/179 (11%)

Query: 146 ATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIVLVLHSVAGSAPMPGT 205
           ATP  ++ P+           +  +  N+L+T++P  P  V++ V   H+   S P P T
Sbjct: 280 ATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAV---HTPQPSIPNP-T 335

Query: 206 DSSSRSMPSS------SYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRP---ASL 256
              + S+P++      S    P   +F GL        P   +TP+++TP+  P   ++L
Sbjct: 336 VIRTPSLPTAPVTSIHSTTTTPVPSIFSGLVS-----LPGPSATPTAATPTPGPTPRSTL 390

Query: 257 GYSGA--AGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPI 313
           G S A  +   P T    +T+ + AST   +S + +    G      P S G+ + TP+
Sbjct: 391 GSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSNPTPV 449



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 46/173 (26%), Positives = 66/173 (38%), Gaps = 24/173 (13%)

Query: 191 LVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTP------ 244
           L L +   SA  P    +  ++P+      PG  LF GL         N+ STP      
Sbjct: 503 LTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGLALFPGLPSPV----ANSTSTPLTLPVQ 558

Query: 245 -----SSSTPSSRPASLGYSGA--AGPRPITQSELATALALASTPESSSHTPTPGTQGHS 297
                ++S  +S P S G S +   GP P T       L ++STP +++      T+  S
Sbjct: 559 SPLATAASASTSVPVSCGSSASLLRGPHPGTSD-----LHISSTPAATTLPVMIKTEPTS 613

Query: 298 SGTSPMSSGVQSGTPITNDL-FSQALQHALQASGQP-SLQSQWQPQLQQLRDM 348
              S       SG P    L  S  L  A  ++  P SL +   P L  L  +
Sbjct: 614 PTPSAFKGPSHSGNPSHGTLGLSGTLGRAYTSTSVPISLSACLNPALSGLSSL 666


>gi|67906195 ankyrin repeat and sterile alpha motif domain
           containing 6 [Homo sapiens]
          Length = 871

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 40/157 (25%), Positives = 64/157 (40%), Gaps = 20/157 (12%)

Query: 238 PNTRSTPSSSTPSSRPASLGYSGAAGPRPI-----TQSELATALALASTPESSSHTPTPG 292
           P+ RS+P    P S P+ L  S A G  P+     T     +  +  S   S + TP+P 
Sbjct: 683 PSHRSSPVGPAPGSSPSELPASPAGGSAPVGKKLETSKRPPSGTSTTSKSTSPTLTPSPS 742

Query: 293 TQGHSSGTSPMSS----------GVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQL 342
            +GH++ +S  SS          G  SGT    D  +  L+       QP  + Q   ++
Sbjct: 743 PKGHTAESSVSSSSSHRQSKSSGGSSSGTITDEDELTGILKKLSLEKYQPIFEEQ---EV 799

Query: 343 QQLRDMGIQDDELSLRALQATGG--DIQAALELIFAG 377
                + + D +L    ++  G    I AA+  + AG
Sbjct: 800 DMEAFLTLTDGDLKELGIKTDGSRQQILAAISELNAG 836


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
           sapiens]
          Length = 907

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 66/306 (21%), Positives = 113/306 (36%), Gaps = 47/306 (15%)

Query: 76  LDFYGIQPGST-----VHVLRKSWPEPDQKPEPVDKVAAMREFRVLHTALHSSSSYREAV 130
           LD + ++P  T           + P P   P P   VAA        TA  ++++   A 
Sbjct: 493 LDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAA 552

Query: 131 FKMLSNK--ESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNA 188
               +    +    +  +TP +++ P         DLFS  A  +      P   + + A
Sbjct: 553 TATTAPPALDIFGDLFESTPEVAAAPKP-DAAPSIDLFSTDAFSSPPQGASPVPESSLTA 611

Query: 189 IVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSST 248
            +L + + A  AP P T +S   + SS   D+ G       S+      P   S  +SS+
Sbjct: 612 DLLSVDAFA--APSPATTASPAKVDSSGVIDLFGDAFGSSASE------PQPASQAASSS 663

Query: 249 PSSRPASLGYSG---AAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSS 305
            +S     G+ G   A  P P+T ++              ++   P  +  + GT+P +S
Sbjct: 664 SASADLLAGFGGSFMAPSPSPVTPAQ--------------NNLLQPNFEA-AFGTTPSTS 708

Query: 306 GVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRALQATGG 365
              S  P   D     L   +  +GQP+  S   P               ++ A +A G 
Sbjct: 709 SSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPP-------------SPAMAASKALGS 755

Query: 366 DIQAAL 371
           D+ ++L
Sbjct: 756 DLDSSL 761


>gi|5032187 transducer of ERBB2, 1 [Homo sapiens]
          Length = 345

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 14/121 (11%)

Query: 233 EDDFHPNTR-----STPSSSTPSSRPASLGYSGAAGPRPI---TQSELATALALASTPES 284
           ++ F+P  +     S P+SS  SS     G+S A  P  +   TQ    T    A+T   
Sbjct: 129 KNSFNPEAQVFMPISDPASSVSSSPSPPFGHSAAVSPTFMPRSTQPLTFTTATFAATKFG 188

Query: 285 SSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQ-ALQHALQASGQPSLQSQWQPQLQ 343
           S+     G     + TSP++ G+       NDL  Q A+  ++ +     L SQ QPQ Q
Sbjct: 189 STKMKNSGRSNKVARTSPINLGLN-----VNDLLKQKAISSSMHSLYGLGLGSQQQPQQQ 243

Query: 344 Q 344
           Q
Sbjct: 244 Q 244


>gi|54607108 zinc finger, MIZ-type containing 2 isoform 1 [Homo
           sapiens]
          Length = 920

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 53/202 (26%), Positives = 76/202 (37%), Gaps = 30/202 (14%)

Query: 177 TLVPAHPALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPG-GFLFEGLSDDEDD 235
           T+ PAH  + + + ++     G+AP       S   PS    D PG G  F G     + 
Sbjct: 705 TVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSVPAPS----DYPGQGSSFLGPGTFPES 760

Query: 236 FHPNTRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPT----- 290
           F P T STP+ +  +  P  + Y     P  +  SE +TA   +    +    PT     
Sbjct: 761 FPPTTPSTPTLAEFTPGPPPISYQSDI-PSSLLTSEKSTACLPSQMAPAGHLDPTHNPGT 819

Query: 291 -----------PGTQGHSSGTSPMS--SGVQSGTPITNDLFSQALQHALQASGQPSLQSQ 337
                      PG Q H S   P S  S  Q+    T +L   A   A    G PS+   
Sbjct: 820 PGLHTSNLGAPPGPQLHHSNPPPASRQSLGQASLGPTGEL---AFSPATGVMGPPSMSGA 876

Query: 338 W---QPQLQQLRDMGIQDDELS 356
               +P L  L ++   D+ LS
Sbjct: 877 GEAPEPALDLLPELTNPDELLS 898


>gi|115334682 SNAP25-interacting protein [Homo sapiens]
          Length = 1183

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 263 GPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQ---SGTPITNDLFS 319
           G  P T SE       A+TP +       G+ G SSG +P+S       S TP       
Sbjct: 591 GSEPETPSEKIEGSNGAATPSAPC-----GSGGRSSGATPVSGPPPPSASSTPAGQPTAV 645

Query: 320 QALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRAL 360
             LQ  L   G  +  S  + QLQQLR + +Q+ E S+RAL
Sbjct: 646 SRLQMQLHLRGLQNSASDLRGQLQQLRKLQLQNQE-SVRAL 685


>gi|54607110 zinc finger, MIZ-type containing 2 isoform 2 [Homo
           sapiens]
          Length = 894

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 53/202 (26%), Positives = 76/202 (37%), Gaps = 30/202 (14%)

Query: 177 TLVPAHPALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPG-GFLFEGLSDDEDD 235
           T+ PAH  + + + ++     G+AP       S   PS    D PG G  F G     + 
Sbjct: 679 TVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSVPAPS----DYPGQGSSFLGPGTFPES 734

Query: 236 FHPNTRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPT----- 290
           F P T STP+ +  +  P  + Y     P  +  SE +TA   +    +    PT     
Sbjct: 735 FPPTTPSTPTLAEFTPGPPPISYQSDI-PSSLLTSEKSTACLPSQMAPAGHLDPTHNPGT 793

Query: 291 -----------PGTQGHSSGTSPMS--SGVQSGTPITNDLFSQALQHALQASGQPSLQSQ 337
                      PG Q H S   P S  S  Q+    T +L   A   A    G PS+   
Sbjct: 794 PGLHTSNLGAPPGPQLHHSNPPPASRQSLGQASLGPTGEL---AFSPATGVMGPPSMSGA 850

Query: 338 W---QPQLQQLRDMGIQDDELS 356
               +P L  L ++   D+ LS
Sbjct: 851 GEAPEPALDLLPELTNPDELLS 872


>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 47/172 (27%), Positives = 67/172 (38%), Gaps = 20/172 (11%)

Query: 197 AGSAPMPGTDSSSRSMPSSS---------YRDMPG---GFLFEGLSDDEDDFHPNTRSTP 244
           + S+    T SSS + P+S+         Y   PG   G + E LS    D++ +  S P
Sbjct: 80  SASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAP 139

Query: 245 SSSTPSSRPASLG-YSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPM 303
           S STPS +P  L  + G+ G    +Q+           P++S     P     S  T P 
Sbjct: 140 SPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPS 199

Query: 304 SSGVQSGTPITNDLFSQALQHAL---QASGQPSLQSQWQPQLQQLRDMGIQD 352
            S  QS  P+   LF     H L   ++   P+      P    L   GI D
Sbjct: 200 PSLAQS--PL--KLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILD 247


>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 47/172 (27%), Positives = 67/172 (38%), Gaps = 20/172 (11%)

Query: 197 AGSAPMPGTDSSSRSMPSSS---------YRDMPG---GFLFEGLSDDEDDFHPNTRSTP 244
           + S+    T SSS + P+S+         Y   PG   G + E LS    D++ +  S P
Sbjct: 80  SASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAP 139

Query: 245 SSSTPSSRPASLG-YSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPM 303
           S STPS +P  L  + G+ G    +Q+           P++S     P     S  T P 
Sbjct: 140 SPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPS 199

Query: 304 SSGVQSGTPITNDLFSQALQHAL---QASGQPSLQSQWQPQLQQLRDMGIQD 352
            S  QS  P+   LF     H L   ++   P+      P    L   GI D
Sbjct: 200 PSLAQS--PL--KLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILD 247


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 27/124 (21%)

Query: 194  HSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTP-SSR 252
            +S AGS+P    D+S   MP+S+Y +                      STP +S P S+ 
Sbjct: 2372 YSQAGSSPTTADDTS---MPTSTYSE---------------------GSTPLTSVPVSTM 2407

Query: 253  PASLGYSGAAGPRPI-TQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGT 311
            P     +      P+ T + + T+   +S+P ++  T  P T   S GT+P++S   S T
Sbjct: 2408 PVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIP-TSPPSEGTTPLASMPVSTT 2466

Query: 312  PITN 315
            P+ +
Sbjct: 2467 PVVS 2470



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 12/105 (11%)

Query: 241  RSTPSSSTPSSRPASLGYSGAAGPRPITQSELAT-------ALALASTPESSSHTPTPGT 293
            RS+P++S  +S P S   +   G  P+T    +T       A  L++TP  +S   T  T
Sbjct: 903  RSSPTTSEGTSMPTS---TPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTST 959

Query: 294  QGHSSGTSPMSSGVQSGTPI--TNDLFSQALQHALQASGQPSLQS 336
            +  SS T+   + + + TP   T  L S  + H L A+ + S  S
Sbjct: 960  EATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLS 1004



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 10/78 (12%)

Query: 242  STPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTP-------TPGTQ 294
            S+P+++  +S P    YS   G  P+T   L+T L ++S   + S TP       T  T+
Sbjct: 1965 SSPTTADGTSMPTP-AYS--EGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTE 2021

Query: 295  GHSSGTSPMSSGVQSGTP 312
            G SS T+   + +Q+ TP
Sbjct: 2022 GSSSPTTAGGTSIQTSTP 2039



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 21/104 (20%)

Query: 234  DDFHPNTRSTPSSSTPSSR-----PASLGYSGAA-------GPRPITQSELATALALAST 281
            D   P T ST +SS+P++      P S    G+           P+  SE +T   L++T
Sbjct: 2836 DTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEAST---LSTT 2892

Query: 282  PESSSHTPTPGTQGHSSGTS------PMSSGVQSGTPITNDLFS 319
            P  +S   T  T+G SS T+      P+S+  +  TP+T+ L S
Sbjct: 2893 PVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVS 2936



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 16/130 (12%)

Query: 198  GSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPS-----SR 252
            GS P+ G   S+  + SS+   +         +   D   P T ST + S+P+     S 
Sbjct: 3103 GSTPLTGVPVSTTPVTSSAISTLS--------TTPVDTSTPVTTSTEAHSSPTTSEGTSM 3154

Query: 253  PASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTP 312
            P S   + + G  P+T   ++T L ++S   + S TP   +   ++ T   SS    GT 
Sbjct: 3155 PTS---TPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTS 3211

Query: 313  ITNDLFSQAL 322
            I     S+ +
Sbjct: 3212 IPTSTPSEGM 3221



 Score = 35.8 bits (81), Expect = 0.066
 Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 15/143 (10%)

Query: 198 GSAP---MPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPS--SSTPSSR 252
           GS P   MP + +   S  +S+    P     +  +  E    P T    S  +STPS  
Sbjct: 450 GSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEG 509

Query: 253 PASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGV----- 307
              L  S +    P+  SE +T   L++TP  +S   T  ++  SS T+P  + +     
Sbjct: 510 STPLT-SMSVSTMPVASSEAST---LSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTP 565

Query: 308 -QSGTPITNDLFSQALQHALQAS 329
            +  TP+TN   S  L  + +AS
Sbjct: 566 SEGSTPLTNMPVSTRLVVSSEAS 588



 Score = 34.7 bits (78), Expect = 0.15
 Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 21/104 (20%)

Query: 234  DDFHPNTRSTPSSSTP-----SSRPASLGYSGAAGPRPITQSELATALA-------LAST 281
            D   P T ST +SS+P     +S P S   + + G  P+T   ++T          L++T
Sbjct: 3248 DSNTPLTTSTEASSSPPTAEGTSMPTS---TPSEGSTPLTSMPVSTTTVASSETSTLSTT 3304

Query: 282  PESSSHTPTPGTQGHSS-----GTS-PMSSGVQSGTPITNDLFS 319
            P  +S   T  +Q  SS     GTS P S+  +  TP+TN  FS
Sbjct: 3305 PADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFS 3348



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 12/105 (11%)

Query: 241  RSTPSSSTPSSRPASLGYSGAAGPRPITQSELAT-------ALALASTPESSSHTPTPGT 293
            RS+P++S  +S P S   + + G  P T   ++T       A  L++TP  +S   T  T
Sbjct: 2199 RSSPTTSEGTSMPTS---TPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTST 2255

Query: 294  QGHSSGTSPMSSGVQSGT--PITNDLFSQALQHALQASGQPSLQS 336
            +  SS T+   + + + T    T  L S  + H L A+ + S  S
Sbjct: 2256 EATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLS 2300



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 43/181 (23%)

Query: 183  PALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSY-------RDMPGGFLFEGLSDDE-- 233
            P   N+ V+    ++ SA    T +   SMP+S+Y       R MP     + L+  E  
Sbjct: 2539 PVDSNSPVVTSTEISSSA----TSAEGTSMPTSTYSEGSTPLRSMPVST--KPLASSEAS 2592

Query: 234  -------DDFHPNTRSTPSSSTPS---------SRPASLGYSGAA---GPRPITQSELAT 274
                   D   P T ST +SS+P+         S P+ +  S  +      P+  SE +T
Sbjct: 2593 TLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEAST 2652

Query: 275  ALALASTPESSSHTPTPGTQGHSSGTS------PMSSGVQSGTPITNDLFSQALQHALQA 328
               L++TP  +    T  T   SS T+      P S+  +  TP+TN L S  L    +A
Sbjct: 2653 ---LSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEA 2709

Query: 329  S 329
            S
Sbjct: 2710 S 2710



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 19/153 (12%)

Query: 193 LHSVAGSAPMPG-TDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTP-- 249
           ++S+  S P  G T  +S S+ +          L     D       ++ ++ SS+TP  
Sbjct: 498 VNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEG 557

Query: 250 SSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTP-------TPGTQGHSSGTS- 301
           +S P S   + + G  P+T   ++T L ++S   ++S TP       T  ++  SS T+ 
Sbjct: 558 TSIPTS---TPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTA 614

Query: 302 -----PMSSGVQSGTPITNDLFSQALQHALQAS 329
                P S+  + GT IT+   S  L  + +AS
Sbjct: 615 EGTSMPTSTYSERGTTITSMSVSTTLVASSEAS 647



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 18/141 (12%)

Query: 204 GTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTP--SSRPASLGYSGA 261
           GT  +S S+ ++         L     D       +T +T SS+T   +S P S    G+
Sbjct: 628 GTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGS 687

Query: 262 AGPRPITQSELATALA-------LASTPESSSHTPTPGTQGHSSGTS------PMSSGVQ 308
               P+T   + T L        L++TP  +S   T  T+  SS T+      P S+  +
Sbjct: 688 T---PLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSE 744

Query: 309 SGTPITNDLFSQALQHALQAS 329
             TP+T+   S+ L  + +AS
Sbjct: 745 GSTPLTSMPVSKTLLTSSEAS 765



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 20/109 (18%)

Query: 241  RSTPSSSTPSSRPASLGYSGAAGPRPITQSELAT-------ALALASTPESSSHTPTPGT 293
            RS+P++S  +S P S   + + G  P+T   ++T       A  L++TP  +S   T  T
Sbjct: 1728 RSSPTTSEGTSMPNS---TPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTST 1784

Query: 294  QGHSS-----GTSPMSSGVQSG-TPITNDLFSQALQHALQASGQPSLQS 336
            +  SS     GTS  +S +  G TP+T    S  + H L A+ + S  S
Sbjct: 1785 EATSSPTTAEGTSIPTSTLSEGMTPLT----STPVSHTLVANSEASTLS 1829



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 21/114 (18%)

Query: 234  DDFHPNTRSTPSSSTP-----SSRPASLGYSGAAGPRPITQSELATALA-------LAST 281
            D   P T ST +SS P     +S P S   + + G  P+T+  ++T +        L++T
Sbjct: 1009 DSNTPLTTSTEASSPPPTAEGTSMPTS---TPSEGSTPLTRMPVSTTMVASSETSTLSTT 1065

Query: 282  PESSSHTPTPGTQGHSSGTS------PMSSGVQSGTPITNDLFSQALQHALQAS 329
            P  +S   T  +Q  SS T+      P S+  +  TP+T+   S  L  + +AS
Sbjct: 1066 PADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAS 1119



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 23/68 (33%), Positives = 30/68 (44%)

Query: 245  SSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMS 304
            SSS  SS PA+L  +      P   S   T + L+ST  +SS   TP T      T   +
Sbjct: 3550 SSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTT 3609

Query: 305  SGVQSGTP 312
            S   + TP
Sbjct: 3610 STQSNSTP 3617



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 7/87 (8%)

Query: 240  TRSTPSSSTPSSRPASLGYSGAAGPRPITQSEL---ATALALASTPESSSHTPTPG---- 292
            T STPS  +P      +  +  A P   T S     + +  + ST  SSS TP  G    
Sbjct: 1622 TISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMP 1681

Query: 293  TQGHSSGTSPMSSGVQSGTPITNDLFS 319
            T  ++ G +P++S     TP+ +   S
Sbjct: 1682 TSTYTEGRTPLTSITVRTTPVASSAIS 1708



 Score = 32.3 bits (72), Expect = 0.73
 Identities = 32/133 (24%), Positives = 58/133 (43%), Gaps = 23/133 (17%)

Query: 198 GSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSR--PAS 255
           GS P+    +S+  + SS    +        L+   +   P T S  +SS+P++   P+ 
Sbjct: 214 GSTPLTSMPASTMKVASSEAITL--------LTTPVEISTPVTISAQASSSPTTAEGPSL 265

Query: 256 LGYSGAAGPRPITQSELATALALASTPESSSHTPT-------PGTQGHSSGTS------P 302
              + + G  P+T+  L+  L ++S   + S TP          T+  SS T+      P
Sbjct: 266 SNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIP 325

Query: 303 MSSGVQSGTPITN 315
            S+  +  TP+T+
Sbjct: 326 TSTYTEGSTPLTS 338



 Score = 32.3 bits (72), Expect = 0.73
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 15/91 (16%)

Query: 234 DDFHPNTRSTPSSSTPS-----SRPASLGYSGAAGPRPITQSELATAL-------ALAST 281
           D   P T ST  SS+P+     S P S  YS   G  P+T   ++T L        L++T
Sbjct: 832 DSNSPVTTSTEVSSSPTPAEGTSMPTST-YS--EGRTPLTSMPVSTTLVATSAISTLSTT 888

Query: 282 PESSSHTPTPGTQGHSSGTSPMSSGVQSGTP 312
           P  +S   T  T+  SS T+   + + + TP
Sbjct: 889 PVDTSTPVTNSTEARSSPTTSEGTSMPTSTP 919



 Score = 32.3 bits (72), Expect = 0.73
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 238  PNTRSTPSSSTPSSRPASLGYSGAAGPR--PITQSELAT-------ALALASTPESSSHT 288
            P T S  +SS+P++   +       G R  P+T   ++T       A  L+ TP  +S  
Sbjct: 2958 PVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTP 3017

Query: 289  PTPGTQGHSSGTSPMSSGVQSGTP 312
             T  T+  SS T+   +G+   TP
Sbjct: 3018 VTTSTEASSSPTTAEGTGIPISTP 3041



 Score = 32.0 bits (71), Expect = 0.95
 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 15/79 (18%)

Query: 245  SSSTPS---SRPASLGYSGAAGP--------RPITQSELATALALASTPESSSHTPTPGT 293
            SS TP+   S P S  YS  + P         P+T S ++T   L++TP  +S   T  T
Sbjct: 3085 SSPTPAEGTSMPIST-YSEGSTPLTGVPVSTTPVTSSAIST---LSTTPVDTSTPVTTST 3140

Query: 294  QGHSSGTSPMSSGVQSGTP 312
            + HSS T+   + + + TP
Sbjct: 3141 EAHSSPTTSEGTSMPTSTP 3159



 Score = 32.0 bits (71), Expect = 0.95
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 234  DDFHPNTRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGT 293
            D   P T S+P++S+P++   +   +  AG      S   T + +++TP +SS   T  T
Sbjct: 3484 DTSTPVTTSSPTNSSPTTAEVTSMPTSTAG----EGSTPLTNMPVSTTPVASSEASTLST 3539

Query: 294  QGHSSGTSPMSSGVQSGTPIT 314
                S T   SS   S +P T
Sbjct: 3540 TPVDSNTFVTSSSQASSSPAT 3560



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 240  TRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSG 299
            T ST +SS+ ++  +S+  S      P   S L T++ L++TP +S    T  T    S 
Sbjct: 2076 TNSTEASSSATAEGSSMTISA-----PSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSN 2130

Query: 300  TSPMSSGVQSGTPITND 316
            +  ++S   S +PI  +
Sbjct: 2131 SPVITSTEVSSSPIPTE 2147



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 28/139 (20%)

Query: 205  TDSSSRSMPSSSYRD-------MPGGFLFEGLSDDE-------DDFHPNTRSTPSSSTPS 250
            T S   SMP+S+  +       MP   +    S+D        D   P T ST ++S+ +
Sbjct: 3147 TTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTT 3206

Query: 251  SRPASLGYSGAA-GPRPITQSELAT-------ALALASTPESSSHTPTPGTQGHSS---- 298
            +   S+  S  + G  P+T   ++        A  L++TP  S+   T  T+  SS    
Sbjct: 3207 AEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTA 3266

Query: 299  -GTS-PMSSGVQSGTPITN 315
             GTS P S+  +  TP+T+
Sbjct: 3267 EGTSMPTSTPSEGSTPLTS 3285



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 40/168 (23%), Positives = 66/168 (39%), Gaps = 18/168 (10%)

Query: 151  SSDPIALGVLQDKDLFSVFADP--NMLDTLVPAHPALVNAIVLVLHSVAGSAPMPGTDSS 208
            SS PIA G       +S  + P  NM  +  P    +V++    L +       P T S+
Sbjct: 3320 SSPPIADGTSMPTSTYSEGSTPLTNMSFSTTP----VVSSEASTLSTTPVDTSTPVTTST 3375

Query: 209  SRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTP-SSRPASLGYSGAAGPRPI 267
              S+  ++          EG S       P+  +TP +S P S+ P            P+
Sbjct: 3376 EASLSPTTA---------EGTSIPTSS--PSEGTTPLASMPVSTTPVVSSEVNTLSTTPV 3424

Query: 268  TQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITN 315
              + L T    AS+  + +   +  T   S G++P+S    S TP+ +
Sbjct: 3425 DSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVAS 3472



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 21/94 (22%)

Query: 240  TRSTPSSSTPS-----SRPASLGYSGAA-------GPRPITQSELATALALASTPESSSH 287
            T ST +SS+P+     S P S    G+           P+  SE +T   L++TP  +S 
Sbjct: 3431 TTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEAST---LSTTPVDTST 3487

Query: 288  TPTPGTQGHSSGTS------PMSSGVQSGTPITN 315
              T  +  +SS T+      P S+  +  TP+TN
Sbjct: 3488 PVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTN 3521



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 29/119 (24%), Positives = 49/119 (41%), Gaps = 16/119 (13%)

Query: 199  SAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTP-SSRPASLG 257
            S P+     +S S P +    MP     EG             STP ++   S+ P    
Sbjct: 3309 STPVTTYSQASSSPPIADGTSMPTSTYSEG-------------STPLTNMSFSTTPVVSS 3355

Query: 258  YSGAAGPRPI-TQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITN 315
             +      P+ T + + T+   + +P ++  T  P T   S GT+P++S   S TP+ +
Sbjct: 3356 EASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIP-TSSPSEGTTPLASMPVSTTPVVS 3413



 Score = 30.0 bits (66), Expect = 3.6
 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 9/82 (10%)

Query: 240  TRSTPSSSTPSSRPASLGYSGAAGPR--PITQSELATAL-------ALASTPESSSHTPT 290
            T ST +SS+P++   S   +   G R  P+T   ++T L        L++TP  +S   T
Sbjct: 2665 TTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVT 2724

Query: 291  PGTQGHSSGTSPMSSGVQSGTP 312
               +  SS T+   + ++  TP
Sbjct: 2725 TSAEASSSPTTAEGTSMRISTP 2746



 Score = 29.6 bits (65), Expect = 4.7
 Identities = 34/125 (27%), Positives = 48/125 (38%), Gaps = 19/125 (15%)

Query: 203 PGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPS------SRPASL 256
           PG  SS+R  P+ S          E  SD    F  +T  T S +TP       S P+  
Sbjct: 103 PGV-SSTRMTPTESRTTS------ESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEE 155

Query: 257 GYSGA---AGPRPITQSELATALALA---STPESSSHTPTPGTQGHSSGTSPMSSGVQSG 310
             S         P+   E  T+L      STP ++S   +       S T P S+  +  
Sbjct: 156 SISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGS 215

Query: 311 TPITN 315
           TP+T+
Sbjct: 216 TPLTS 220



 Score = 29.3 bits (64), Expect = 6.1
 Identities = 48/207 (23%), Positives = 82/207 (39%), Gaps = 31/207 (14%)

Query: 123 SSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVPAH 182
           +S+Y E    + S   S   + VAT  +S+  +++  +    L +   +P+ L T   A 
Sbjct: 326 TSTYTEGSTPLTSTPAST--MPVATSEMST--LSITPVDTSTLVTTSTEPSSLPTTAEAT 381

Query: 183 PALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRS 242
             L + +        GS P+     S+  + SS             +  D   F   T S
Sbjct: 382 SMLTSTLS------EGSTPLTNMPVSTILVASSEASTT------STIPVDSKTF-VTTAS 428

Query: 243 TPSSSTPSSRPASLGYSGAA-GPRPITQSELAT-------ALALASTPESSSHTPTPGTQ 294
             SSS  ++   S+  S  + G  P+T   ++T       A  L++TP  S    T  T+
Sbjct: 429 EASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTE 488

Query: 295 GHSS------GTSPMSSGVQSGTPITN 315
             SS       + P S+  +  TP+T+
Sbjct: 489 ASSSPPTAEVNSMPTSTPSEGSTPLTS 515



 Score = 29.3 bits (64), Expect = 6.1
 Identities = 38/150 (25%), Positives = 57/150 (38%), Gaps = 29/150 (19%)

Query: 198 GSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRPASLG 257
           GS P+     S+R + SS           E  +        NT  T SS   SS   + G
Sbjct: 568 GSTPLTNMPVSTRLVVSS-----------EASTTSTTPADSNTFVTTSSEASSSSTTAEG 616

Query: 258 YSGAAGP-----RPITQSELATALA-------LASTPESSSHTPTPGTQGHSSGTS---- 301
            S            IT   ++T L        L++TP  S+   T  T+  SS T+    
Sbjct: 617 TSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGT 676

Query: 302 --PMSSGVQSGTPITNDLFSQALQHALQAS 329
             P S+  +  TP+T+   +  L  + +AS
Sbjct: 677 SMPTSTYTEGSTPLTSMPVNTTLVASSEAS 706



 Score = 29.3 bits (64), Expect = 6.1
 Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 9/88 (10%)

Query: 234  DDFHPNTRSTPSSSTPS-SRPASLGYSGAA-GPRPITQSELAT-------ALALASTPES 284
            D+  P T ST + S+P+ S   S+  S  + G  P+T   ++T       A  L++TP  
Sbjct: 1363 DNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVD 1422

Query: 285  SSHTPTPGTQGHSSGTSPMSSGVQSGTP 312
            +S   T   +  SS T+     + + TP
Sbjct: 1423 TSTPGTTSAEATSSPTTAEGISIPTSTP 1450



 Score = 28.9 bits (63), Expect = 8.0
 Identities = 41/154 (26%), Positives = 64/154 (41%), Gaps = 19/154 (12%)

Query: 167  SVFADPNMLDTLVPAHPALVN---AIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGG 223
            S  ++ + L T +P    LV    A  L+   V    P+  ++  S S   +    MP  
Sbjct: 1271 STTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTS 1330

Query: 224  FLFEGLSDDEDDFHPNTRSTPSSST--PSSRPASLGYSGAAGPRPITQSELATALALAST 281
               EG +       P T S P ++T   SS  + L  +      P+T S  A      S+
Sbjct: 1331 TYSEGRT-------PLT-SIPVNTTLVASSAISILSTTPVDNSTPVTTSTEA-----CSS 1377

Query: 282  PESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITN 315
            P +S  T  P +   S GT+P++S   S TP+ +
Sbjct: 1378 PTTSEGTSMPNSNP-SEGTTPLTSIPVSTTPVVS 1410


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 32/114 (28%), Positives = 46/114 (40%), Gaps = 4/114 (3%)

Query: 200  APMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRPASLGYS 259
            +P PG+  S    PSS Y   PGG +    S     + P +    +  +PS  P S  YS
Sbjct: 1566 SPTPGSPGSPG--PSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYS 1623

Query: 260  GAAGPRPITQSELATALALASTPESSSHTPT-PGTQGHSSGTSPMSSGVQSGTP 312
                P     S   +  + + +P S S++PT P     S   SP S      +P
Sbjct: 1624 -PTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1676



 Score = 28.9 bits (63), Expect = 8.0
 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 240  TRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPT-PGTQGHSS 298
            T  + S ++PS  P S  YS ++ PR   QS   T  + + +P S S++PT P     S 
Sbjct: 1786 TSPSYSPTSPSYSPTSPSYSPSS-PRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSP 1844

Query: 299  GTSPMS 304
              SP S
Sbjct: 1845 SYSPSS 1850


>gi|24497609 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 44/162 (27%), Positives = 61/162 (37%), Gaps = 33/162 (20%)

Query: 185 LVNAIVLVLHSVAGSAPM-----PGTDSSSRSMPSSSYR------DMPGGFLFEGLSDDE 233
           L NAI   + S  G+AP      P T S + +  S  +         P GF      +  
Sbjct: 121 LTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSA 180

Query: 234 DDFHPNT--------------RSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALA 279
               P T               + P++ TP++   S G S  A       S   T L+L 
Sbjct: 181 QPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC 240

Query: 280 STPESSSHTPTPGTQGHS-------SGTSPMSSGVQSGTPIT 314
            TP +++  PT GTQG S       SGTS  +S   + T  T
Sbjct: 241 -TPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATT 281


>gi|24497607 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 44/162 (27%), Positives = 61/162 (37%), Gaps = 33/162 (20%)

Query: 185 LVNAIVLVLHSVAGSAPM-----PGTDSSSRSMPSSSYR------DMPGGFLFEGLSDDE 233
           L NAI   + S  G+AP      P T S + +  S  +         P GF      +  
Sbjct: 121 LTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSA 180

Query: 234 DDFHPNT--------------RSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALA 279
               P T               + P++ TP++   S G S  A       S   T L+L 
Sbjct: 181 QPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC 240

Query: 280 STPESSSHTPTPGTQGHS-------SGTSPMSSGVQSGTPIT 314
            TP +++  PT GTQG S       SGTS  +S   + T  T
Sbjct: 241 -TPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATT 281


>gi|24497605 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 44/162 (27%), Positives = 61/162 (37%), Gaps = 33/162 (20%)

Query: 185 LVNAIVLVLHSVAGSAPM-----PGTDSSSRSMPSSSYR------DMPGGFLFEGLSDDE 233
           L NAI   + S  G+AP      P T S + +  S  +         P GF      +  
Sbjct: 121 LTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSA 180

Query: 234 DDFHPNT--------------RSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALA 279
               P T               + P++ TP++   S G S  A       S   T L+L 
Sbjct: 181 QPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC 240

Query: 280 STPESSSHTPTPGTQGHS-------SGTSPMSSGVQSGTPIT 314
            TP +++  PT GTQG S       SGTS  +S   + T  T
Sbjct: 241 -TPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATT 281


>gi|24497603 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 44/162 (27%), Positives = 61/162 (37%), Gaps = 33/162 (20%)

Query: 185 LVNAIVLVLHSVAGSAPM-----PGTDSSSRSMPSSSYR------DMPGGFLFEGLSDDE 233
           L NAI   + S  G+AP      P T S + +  S  +         P GF      +  
Sbjct: 121 LTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSA 180

Query: 234 DDFHPNT--------------RSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALA 279
               P T               + P++ TP++   S G S  A       S   T L+L 
Sbjct: 181 QPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC 240

Query: 280 STPESSSHTPTPGTQGHS-------SGTSPMSSGVQSGTPIT 314
            TP +++  PT GTQG S       SGTS  +S   + T  T
Sbjct: 241 -TPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATT 281


>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 54/210 (25%), Positives = 79/210 (37%), Gaps = 21/210 (10%)

Query: 90  LRKSWPEPDQKPEPVDKVAAMREFRVLHTALHSSSSYREAVFKMLSNKESLDQIIVATPG 149
           LR     P + PEP   V A    R             +   K    +E  ++   A+ G
Sbjct: 491 LRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGG 550

Query: 150 LSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIVLVLHSVAGSAPMPGTDSSS 209
            S+DP+A  VL D D   +     M     PA PAL         SV   AP P T + +
Sbjct: 551 PSTDPLAGLVLSDNDRSLLERWTRMAR---PAAPALT--------SVPAPAPAP-TPTPT 598

Query: 210 RSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRPASLGYSGAAGPRPI-T 268
              P+S     P G + +            +   P  + P   PA    +G  GP P+  
Sbjct: 599 PVQPTSP----PPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAP-HPTGPPGPIPVPA 653

Query: 269 QSELATALALASTPESSSHTPTPGTQGHSS 298
             ++AT+ +L +   + S  P PG  G S+
Sbjct: 654 PPQIATSTSLLA---AQSLVPPPGLPGSST 680


>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 54/210 (25%), Positives = 79/210 (37%), Gaps = 21/210 (10%)

Query: 90  LRKSWPEPDQKPEPVDKVAAMREFRVLHTALHSSSSYREAVFKMLSNKESLDQIIVATPG 149
           LR     P + PEP   V A    R             +   K    +E  ++   A+ G
Sbjct: 491 LRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGG 550

Query: 150 LSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIVLVLHSVAGSAPMPGTDSSS 209
            S+DP+A  VL D D   +     M     PA PAL         SV   AP P T + +
Sbjct: 551 PSTDPLAGLVLSDNDRSLLERWTRMAR---PAAPALT--------SVPAPAPAP-TPTPT 598

Query: 210 RSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRPASLGYSGAAGPRPI-T 268
              P+S     P G + +            +   P  + P   PA    +G  GP P+  
Sbjct: 599 PVQPTSP----PPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAP-HPTGPPGPIPVPA 653

Query: 269 QSELATALALASTPESSSHTPTPGTQGHSS 298
             ++AT+ +L +   + S  P PG  G S+
Sbjct: 654 PPQIATSTSLLA---AQSLVPPPGLPGSST 680


>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 54/210 (25%), Positives = 79/210 (37%), Gaps = 21/210 (10%)

Query: 90  LRKSWPEPDQKPEPVDKVAAMREFRVLHTALHSSSSYREAVFKMLSNKESLDQIIVATPG 149
           LR     P + PEP   V A    R             +   K    +E  ++   A+ G
Sbjct: 491 LRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGG 550

Query: 150 LSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIVLVLHSVAGSAPMPGTDSSS 209
            S+DP+A  VL D D   +     M     PA PAL         SV   AP P T + +
Sbjct: 551 PSTDPLAGLVLSDNDRSLLERWTRMAR---PAAPALT--------SVPAPAPAP-TPTPT 598

Query: 210 RSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRPASLGYSGAAGPRPI-T 268
              P+S     P G + +            +   P  + P   PA    +G  GP P+  
Sbjct: 599 PVQPTSP----PPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAP-HPTGPPGPIPVPA 653

Query: 269 QSELATALALASTPESSSHTPTPGTQGHSS 298
             ++AT+ +L +   + S  P PG  G S+
Sbjct: 654 PPQIATSTSLLA---AQSLVPPPGLPGSST 680


>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
           sapiens]
          Length = 677

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 54/210 (25%), Positives = 79/210 (37%), Gaps = 21/210 (10%)

Query: 90  LRKSWPEPDQKPEPVDKVAAMREFRVLHTALHSSSSYREAVFKMLSNKESLDQIIVATPG 149
           LR     P + PEP   V A    R             +   K    +E  ++   A+ G
Sbjct: 352 LRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKERGAGASGG 411

Query: 150 LSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIVLVLHSVAGSAPMPGTDSSS 209
            S+DP+A  VL D D   +     M     PA PAL         SV   AP P T + +
Sbjct: 412 PSTDPLAGLVLSDNDRSLLERWTRMAR---PAAPALT--------SVPAPAPAP-TPTPT 459

Query: 210 RSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRPASLGYSGAAGPRPI-T 268
              P+S     P G + +            +   P  + P   PA    +G  GP P+  
Sbjct: 460 PVQPTSP----PPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAP-HPTGPPGPIPVPA 514

Query: 269 QSELATALALASTPESSSHTPTPGTQGHSS 298
             ++AT+ +L +   + S  P PG  G S+
Sbjct: 515 PPQIATSTSLLA---AQSLVPPPGLPGSST 541


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 46/155 (29%), Positives = 59/155 (38%), Gaps = 27/155 (17%)

Query: 203  PGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRPASLGYSGAA 262
            PG  S   + PS +     GG    GL +    F P     PSS +PSS P  LG     
Sbjct: 931  PGARSPQAAQPSPAPPGARGGL---GLPEH---FLP---PPPSSRSPSSSPGQLG----- 976

Query: 263  GPRPITQSELATALALASTPESSSHTPTPGT--QGHSSGTSPMSSGVQSG------TPIT 314
              +P  +  L  A    STPE+    P P +   G S G SP+    + G      +P  
Sbjct: 977  --QPPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGASPVGFTPRGGLSPPGHSPGP 1034

Query: 315  NDLFSQALQHALQASGQ---PSLQSQWQPQLQQLR 346
               F  A   A  + G    P   S   PQ+ Q R
Sbjct: 1035 PRTFPSAPPRASGSHGSLLLPPASSPPPPQVPQRR 1069



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 16/97 (16%)

Query: 238 PNTRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHS 297
           P+   TPSSS+   +  + G+S  AG  P+  S              SS +P PG  G  
Sbjct: 846 PSQVDTPSSSSFHIQQLA-GFSAPAGLSPLLPS--------------SSSSPPPGACGSP 890

Query: 298 SGTSPMSSGVQSGTPITNDLFSQALQHALQASGQPSL 334
           S  +P S+GV + T      F +AL  +L +S  P L
Sbjct: 891 SAPTP-SAGVAATTIAGFGHFHKALGGSLSSSDSPLL 926


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 30/112 (26%), Positives = 41/112 (36%), Gaps = 5/112 (4%)

Query: 195 SVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPS---- 250
           + A +A   G   +    P  + RD  G    +  S D    +P  +  P  S P     
Sbjct: 47  AAAAAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLP 106

Query: 251 -SRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTS 301
            S   SLG SGA  P P+    L +   + S+   S   P P   G S   S
Sbjct: 107 PSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVS 158


>gi|67010025 Sp4 transcription factor [Homo sapiens]
          Length = 784

 Score = 35.8 bits (81), Expect = 0.066
 Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 6/102 (5%)

Query: 278 LASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQSQ 337
           +ASTP +S           SS +S  ++G  S T   +   S   Q  +     PS   Q
Sbjct: 105 VASTPPASKENNVSQPASSSSSSSSSNNGSASPTKTKSGNSSTPGQFQVIQVQNPSGSVQ 164

Query: 338 WQ--PQLQQLRDMGIQDDELSLRALQATGGDIQAALELIFAG 377
           +Q  PQLQ +    IQ +  S  +LQ    D+Q  ++LI AG
Sbjct: 165 YQVIPQLQTVEGQQIQINPTSSSSLQ----DLQGQIQLISAG 202



 Score = 32.3 bits (72), Expect = 0.73
 Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 3/125 (2%)

Query: 252 RPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGT 311
           +PA+   SG +    +  +   T  + ++ PES S + T  T   +S TS  +    + T
Sbjct: 285 QPAATADSGTSNGNQLVSTPTNTTTSASTMPESPSSSTTCTTTASTSLTSSDTLVSSADT 344

Query: 312 PITNDLFSQALQHALQASGQPSL---QSQWQPQLQQLRDMGIQDDELSLRALQATGGDIQ 368
                  + + +  ++ S  P+    ++Q   QLQ       QD   SL+ +Q  G  I 
Sbjct: 345 GQYASTSASSSERTIEESQTPAATESEAQSSSQLQPNGMQNAQDQSNSLQQVQIVGQPIL 404

Query: 369 AALEL 373
             +++
Sbjct: 405 QQIQI 409



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 30/118 (25%), Positives = 45/118 (38%), Gaps = 1/118 (0%)

Query: 239 NTRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSS 298
           +T  T S +  SS       S +A     T  E  T  A  S  +SSS     G Q    
Sbjct: 329 STSLTSSDTLVSSADTGQYASTSASSSERTIEESQTPAATESEAQSSSQLQPNGMQNAQD 388

Query: 299 GTSPMSSGVQSGTPITNDL-FSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDEL 355
            ++ +      G PI   +   Q  Q  +QA    S Q Q    +Q ++   +Q+ +L
Sbjct: 389 QSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQL 446


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,298,749
Number of Sequences: 37866
Number of extensions: 844421
Number of successful extensions: 4643
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 302
Number of HSP's that attempted gapping in prelim test: 3697
Number of HSP's gapped (non-prelim): 1112
length of query: 380
length of database: 18,247,518
effective HSP length: 104
effective length of query: 276
effective length of database: 14,309,454
effective search space: 3949409304
effective search space used: 3949409304
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.