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Search of human proteins with 40807491
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40807491 acyl-CoA synthetase long-chain family member 1
[Homo sapiens]
(698 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo... 1419 0.0
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo... 1004 0.0
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo... 994 0.0
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 876 0.0
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 876 0.0
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 876 0.0
gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo... 323 3e-88
gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo... 323 3e-88
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor... 310 2e-84
gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo... 310 2e-84
gi|27477105 lipidosin [Homo sapiens] 181 3e-45
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens] 155 1e-37
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 82 2e-15
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 82 2e-15
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 79 1e-14
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 60 5e-09
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 60 7e-09
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 60 7e-09
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 60 9e-09
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 58 3e-08
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 48 4e-05
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 47 6e-05
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 47 6e-05
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 46 1e-04
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 44 5e-04
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 42 0.002
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 36 0.11
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens] 34 0.40
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 34 0.40
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 34 0.52
>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
sapiens]
Length = 698
Score = 1419 bits (3673), Expect = 0.0
Identities = 698/698 (100%), Positives = 698/698 (100%)
Query: 1 MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60
MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ
Sbjct: 1 MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60
Query: 61 SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120
SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW
Sbjct: 61 SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120
Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180
LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT
Sbjct: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180
Query: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240
LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR
Sbjct: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240
Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300
CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF
Sbjct: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300
Query: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360
VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP
Sbjct: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360
Query: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420
TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV
Sbjct: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420
Query: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480
QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV
Sbjct: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480
Query: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD
Sbjct: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
Query: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600
IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI
Sbjct: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600
Query: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660
VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP
Sbjct: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660
Query: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV 698
ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV
Sbjct: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV 698
>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
b [Homo sapiens]
Length = 722
Score = 1004 bits (2596), Expect = 0.0
Identities = 466/694 (67%), Positives = 570/694 (82%)
Query: 1 MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60
MQ E+ R R+PEL D Q+ R+L TL+ GA AA+ +W+ RPK L+PPC+L MQ
Sbjct: 26 MQTQEILRILRLPELGDLGQFFRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQ 85
Query: 61 SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120
S EV SGGARRS + + L ++YDD T+Y+ F+RG+ +S NGPCLG RKP QPY+W
Sbjct: 86 SEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQW 145
Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180
LSY++VA+ +E +GS L+Q K DQFIG+FAQNRPEW+I+E C+ YSMV+VPLYDT
Sbjct: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205
Query: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240
LG AI YI+N A++S V VDKP+KA LLLE VE K PGLK+I++MD + L ERGQ+
Sbjct: 206 LGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQK 265
Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300
CGV + SM+A+ED G+ N + P PP P+DL+++CFTSGTTGNPKGAM+TH N+V+D S F
Sbjct: 266 CGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGF 325
Query: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360
+K TE + P DD LISFLPLAHMFERV++ V+ CHG ++GFFQGDIRLL DD+K L P
Sbjct: 326 LKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCP 385
Query: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420
T+FPVVPRLLNRM+D+IF QANT LKRWLL+FA+KRK+AE+RSGIIRN+S+WD L F+K+
Sbjct: 386 TIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKI 445
Query: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480
Q+SLGG VR++VTGAAP S TVL FLRAALGCQ YEGYGQTECTAGC T PGDWT+GHV
Sbjct: 446 QASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHV 505
Query: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
GAP+PCN IKLVDVEE+NY A +GEGE+CV+GPNVF+GYLKDP +T EALD DGWLHTGD
Sbjct: 506 GAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGD 565
Query: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600
IGKWLP GTLKIIDRKKHIFKLAQGEY+APEKIENIY+RS+PVAQ++VHG+SL+AFL+ I
Sbjct: 566 IGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGI 625
Query: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660
VVPD E + SWAQKRG EG++ +LC NKD+KKAILEDMVRLGK+SGL FEQVK I +H
Sbjct: 626 VVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHS 685
Query: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYS 694
++FS+ NGLLTPT+KAKRPELR YF+ QI++LYS
Sbjct: 686 DMFSVQNGLLTPTLKAKRPELREYFKKQIEELYS 719
>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
a [Homo sapiens]
Length = 722
Score = 994 bits (2571), Expect = 0.0
Identities = 463/694 (66%), Positives = 568/694 (81%)
Query: 1 MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60
MQ E+ R R+PEL D Q+ R+L TL+ GA AA+ +W+ RPK L+PPC+L MQ
Sbjct: 26 MQTQEILRILRLPELGDLGQFFRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQ 85
Query: 61 SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120
S EV SGGARRS + + L ++YDD T+Y+ F+RG+ +S NGPCLG RKP QPY+W
Sbjct: 86 SEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQW 145
Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180
LSY++VA+ +E +GS L+Q K DQFIG+FAQNRPEW+I+E C+ YSMV+VPLYDT
Sbjct: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205
Query: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240
LG AI YI+N A++S V VDKP+KA LLLE VE K PGLK+I++MD + L ERGQ+
Sbjct: 206 LGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQK 265
Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300
CGV + SM+A+ED G+ N + P PP P+DL+++CFTSGTTGNPKGAM+TH N+V+D S F
Sbjct: 266 CGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGF 325
Query: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360
+K TE+ P D IS+LPLAHMFER+V+ V+ CHG ++GFFQGDIRLL DD+K L P
Sbjct: 326 LKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCP 385
Query: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420
T+FPVVPRLLNRM+D+IF QANT LKRWLL+FA+KRK+AE+RSGIIRN+S+WD L F+K+
Sbjct: 386 TIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKI 445
Query: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480
Q+SLGG VR++VTGAAP S TVL FLRAALGCQ YEGYGQTECTAGC T PGDWT+GHV
Sbjct: 446 QASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHV 505
Query: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
GAP+PCN IKLVDVEE+NY A +GEGE+CV+GPNVF+GYLKDP +T EALD DGWLHTGD
Sbjct: 506 GAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGD 565
Query: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600
IGKWLP GTLKIIDRKKHIFKLAQGEY+APEKIENIY+RS+PVAQ++VHG+SL+AFL+ I
Sbjct: 566 IGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGI 625
Query: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660
VVPD E + SWAQKRG EG++ +LC NKD+KKAILEDMVRLGK+SGL FEQVK I +H
Sbjct: 626 VVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHS 685
Query: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYS 694
++FS+ NGLLTPT+KAKRPELR YF+ QI++LYS
Sbjct: 686 DMFSVQNGLLTPTLKAKRPELREYFKKQIEELYS 719
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 876 bits (2263), Expect = 0.0
Identities = 414/673 (61%), Positives = 527/673 (78%), Gaps = 2/673 (0%)
Query: 25 LPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVY 84
LPT L+ F A W TRP+P+ P DL+ QSV + GGAR+ +++
Sbjct: 12 LPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGI--EGGARKGVSQKNNDLTSC 69
Query: 85 FYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKT 144
+ D T+YE FQRG+ VS+NGPCLG RKP+QPY WLSYKQV++ +E +GS L+ KG+K+
Sbjct: 70 CFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKS 129
Query: 145 APDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPE 204
+PDQF+GIFAQNRPEW+I E C+ YSMV VPLYDTLG EAI +IVNKA++++V D P+
Sbjct: 130 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 189
Query: 205 KAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKP 264
KA +L+ VE P LK+I++MD + +L +RG++ G+E+ S+ E+LG+ + RKP P
Sbjct: 190 KALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVP 249
Query: 265 PAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAH 324
P+PEDL+VICFTSGTTG+PKGAM+TH+NIVS+ +AF+K E+ P PDD IS+LPLAH
Sbjct: 250 PSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309
Query: 325 MFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTT 384
MFER+V+ V+ GA++GFFQGDIRLL DD+K L+PT+FP VPRLLNR++D++ +A T
Sbjct: 310 MFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP 369
Query: 385 LKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLT 444
LK++LL A K EL+ GIIR++S WD+LIF K+Q SLGGRVR++VTGAAP+S +V+T
Sbjct: 370 LKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMT 429
Query: 445 FLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG 504
F RAA+GCQ YE YGQTECT GC T+PGDWT+GHVG P+ CN +KL DV +MNY
Sbjct: 430 FFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN 489
Query: 505 EGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQ 564
EGEVC+KG NVF+GYLKDP KT EALD DGWLHTGDIG+WLPNGTLKIIDRKK+IFKLAQ
Sbjct: 490 EGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQ 549
Query: 565 GEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL 624
GEYIAPEKIENIY RS+PV Q+FVHGESL++ L+ +VVPD + L S+A K G +GSFEEL
Sbjct: 550 GEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEEL 609
Query: 625 CRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNY 684
C+N+ V++AILED+ ++GK+SGLK FEQVK I LHPE FSI+NGLLTPT+KAKR EL Y
Sbjct: 610 CQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKY 669
Query: 685 FRSQIDDLYSTIK 697
FR+QID LY I+
Sbjct: 670 FRTQIDSLYEHIQ 682
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 876 bits (2263), Expect = 0.0
Identities = 414/673 (61%), Positives = 527/673 (78%), Gaps = 2/673 (0%)
Query: 25 LPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVY 84
LPT L+ F A W TRP+P+ P DL+ QSV + GGAR+ +++
Sbjct: 12 LPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGI--EGGARKGVSQKNNDLTSC 69
Query: 85 FYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKT 144
+ D T+YE FQRG+ VS+NGPCLG RKP+QPY WLSYKQV++ +E +GS L+ KG+K+
Sbjct: 70 CFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKS 129
Query: 145 APDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPE 204
+PDQF+GIFAQNRPEW+I E C+ YSMV VPLYDTLG EAI +IVNKA++++V D P+
Sbjct: 130 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 189
Query: 205 KAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKP 264
KA +L+ VE P LK+I++MD + +L +RG++ G+E+ S+ E+LG+ + RKP P
Sbjct: 190 KALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVP 249
Query: 265 PAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAH 324
P+PEDL+VICFTSGTTG+PKGAM+TH+NIVS+ +AF+K E+ P PDD IS+LPLAH
Sbjct: 250 PSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309
Query: 325 MFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTT 384
MFER+V+ V+ GA++GFFQGDIRLL DD+K L+PT+FP VPRLLNR++D++ +A T
Sbjct: 310 MFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP 369
Query: 385 LKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLT 444
LK++LL A K EL+ GIIR++S WD+LIF K+Q SLGGRVR++VTGAAP+S +V+T
Sbjct: 370 LKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMT 429
Query: 445 FLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG 504
F RAA+GCQ YE YGQTECT GC T+PGDWT+GHVG P+ CN +KL DV +MNY
Sbjct: 430 FFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN 489
Query: 505 EGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQ 564
EGEVC+KG NVF+GYLKDP KT EALD DGWLHTGDIG+WLPNGTLKIIDRKK+IFKLAQ
Sbjct: 490 EGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQ 549
Query: 565 GEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL 624
GEYIAPEKIENIY RS+PV Q+FVHGESL++ L+ +VVPD + L S+A K G +GSFEEL
Sbjct: 550 GEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEEL 609
Query: 625 CRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNY 684
C+N+ V++AILED+ ++GK+SGLK FEQVK I LHPE FSI+NGLLTPT+KAKR EL Y
Sbjct: 610 CQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKY 669
Query: 685 FRSQIDDLYSTIK 697
FR+QID LY I+
Sbjct: 670 FRTQIDSLYEHIQ 682
>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
a [Homo sapiens]
Length = 739
Score = 876 bits (2263), Expect = 0.0
Identities = 414/673 (61%), Positives = 527/673 (78%), Gaps = 2/673 (0%)
Query: 25 LPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVY 84
LPT L+ F A W TRP+P+ P DL+ QSV + GGAR+ +++
Sbjct: 68 LPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGI--EGGARKGVSQKNNDLTSC 125
Query: 85 FYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKT 144
+ D T+YE FQRG+ VS+NGPCLG RKP+QPY WLSYKQV++ +E +GS L+ KG+K+
Sbjct: 126 CFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKS 185
Query: 145 APDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPE 204
+PDQF+GIFAQNRPEW+I E C+ YSMV VPLYDTLG EAI +IVNKA++++V D P+
Sbjct: 186 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 245
Query: 205 KAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKP 264
KA +L+ VE P LK+I++MD + +L +RG++ G+E+ S+ E+LG+ + RKP P
Sbjct: 246 KALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVP 305
Query: 265 PAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAH 324
P+PEDL+VICFTSGTTG+PKGAM+TH+NIVS+ +AF+K E+ P PDD IS+LPLAH
Sbjct: 306 PSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 365
Query: 325 MFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTT 384
MFER+V+ V+ GA++GFFQGDIRLL DD+K L+PT+FP VPRLLNR++D++ +A T
Sbjct: 366 MFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP 425
Query: 385 LKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLT 444
LK++LL A K EL+ GIIR++S WD+LIF K+Q SLGGRVR++VTGAAP+S +V+T
Sbjct: 426 LKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMT 485
Query: 445 FLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG 504
F RAA+GCQ YE YGQTECT GC T+PGDWT+GHVG P+ CN +KL DV +MNY
Sbjct: 486 FFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN 545
Query: 505 EGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQ 564
EGEVC+KG NVF+GYLKDP KT EALD DGWLHTGDIG+WLPNGTLKIIDRKK+IFKLAQ
Sbjct: 546 EGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQ 605
Query: 565 GEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL 624
GEYIAPEKIENIY RS+PV Q+FVHGESL++ L+ +VVPD + L S+A K G +GSFEEL
Sbjct: 606 GEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEEL 665
Query: 625 CRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNY 684
C+N+ V++AILED+ ++GK+SGLK FEQVK I LHPE FSI+NGLLTPT+KAKR EL Y
Sbjct: 666 CQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKY 725
Query: 685 FRSQIDDLYSTIK 697
FR+QID LY I+
Sbjct: 726 FRTQIDSLYEHIQ 738
>gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 323 bits (828), Expect = 3e-88
Identities = 205/599 (34%), Positives = 321/599 (53%), Gaps = 36/599 (6%)
Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177
Y WLSY+ V + G+ L G K P I IF + R EW+I Q CF Y+ +V L
Sbjct: 132 YNWLSYEDVFVRAFNFGNGLQMLGQK--PKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189
Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVER 237
Y TLG AI + +N+ E++ + K E + L+ + + L+P L+ I+ +D E
Sbjct: 190 YATLGGPAIVHALNETEVTNIITSK-ELLQTKLKDIVS-LVPRLRHIITVDGKPPTWSEF 247
Query: 238 GQRCGVEVTSMKAMEDLGRANRRKPKP---PAPEDLAVICFTSGTTGNPKGAMVTHRNIV 294
+ G+ V +M A+E LG + +P P P D+AVI +TSG+TG PKG M++H NI+
Sbjct: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305
Query: 295 SDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMD- 353
+ + E +D I +LPLAH+ E E V L HG +IG+ + L D
Sbjct: 306 AGITGMA---ERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360
Query: 354 ----------DLKVLQPTVFPVVPRLLNRMFDRIFGQAN--TTLKRWLLDFASKRKEAEL 401
D +L+PT+ VP +++R++ + + + ++ +R L A K ++
Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
Query: 402 RSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQT 461
G RN L D +F KV+S LGG +RL++ G AP+SAT F+ C +GYG T
Sbjct: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478
Query: 462 ECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKGPNVFQG 518
E ++ D+ G VGAP+ C IKL + EE Y + GE+ + G +V G
Sbjct: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538
Query: 519 YLKDPAKTAEAL--DKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIE 574
Y K+ AKT D++G WL TGDIG++ P+G LKIIDRKK + KL GEY++ K+E
Sbjct: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
Query: 575 NIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAI 634
V + + S +++I VVP+ + L A+K+G +G++EELC + +++ +
Sbjct: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658
Query: 635 LEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLY 693
L+ + + L+ FE I L PE ++ + GL+T K KR EL+ ++++ I+ +Y
Sbjct: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
>gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 323 bits (828), Expect = 3e-88
Identities = 205/599 (34%), Positives = 321/599 (53%), Gaps = 36/599 (6%)
Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177
Y WLSY+ V + G+ L G K P I IF + R EW+I Q CF Y+ +V L
Sbjct: 132 YNWLSYEDVFVRAFNFGNGLQMLGQK--PKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189
Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVER 237
Y TLG AI + +N+ E++ + K E + L+ + + L+P L+ I+ +D E
Sbjct: 190 YATLGGPAIVHALNETEVTNIITSK-ELLQTKLKDIVS-LVPRLRHIITVDGKPPTWSEF 247
Query: 238 GQRCGVEVTSMKAMEDLGRANRRKPKP---PAPEDLAVICFTSGTTGNPKGAMVTHRNIV 294
+ G+ V +M A+E LG + +P P P D+AVI +TSG+TG PKG M++H NI+
Sbjct: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305
Query: 295 SDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMD- 353
+ + E +D I +LPLAH+ E E V L HG +IG+ + L D
Sbjct: 306 AGITGMA---ERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360
Query: 354 ----------DLKVLQPTVFPVVPRLLNRMFDRIFGQAN--TTLKRWLLDFASKRKEAEL 401
D +L+PT+ VP +++R++ + + + ++ +R L A K ++
Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
Query: 402 RSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQT 461
G RN L D +F KV+S LGG +RL++ G AP+SAT F+ C +GYG T
Sbjct: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478
Query: 462 ECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKGPNVFQG 518
E ++ D+ G VGAP+ C IKL + EE Y + GE+ + G +V G
Sbjct: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538
Query: 519 YLKDPAKTAEAL--DKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIE 574
Y K+ AKT D++G WL TGDIG++ P+G LKIIDRKK + KL GEY++ K+E
Sbjct: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
Query: 575 NIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAI 634
V + + S +++I VVP+ + L A+K+G +G++EELC + +++ +
Sbjct: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658
Query: 635 LEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLY 693
L+ + + L+ FE I L PE ++ + GL+T K KR EL+ ++++ I+ +Y
Sbjct: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
[Homo sapiens]
Length = 670
Score = 310 bits (795), Expect = 2e-84
Identities = 199/605 (32%), Positives = 316/605 (52%), Gaps = 48/605 (7%)
Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177
Y+W++Y +V GS L G K P I IF + R EW+I Q CF Y+ +V L
Sbjct: 82 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139
Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKL------IPGLKIIVVMDAYG 231
Y TLG EA+ + +N++E S + +E +E+KL I +K I+ +D
Sbjct: 140 YATLGKEAVVHGLNESEASYLITS--------VELLESKLKTALLDISCVKHIIYVDNKA 191
Query: 232 SELVERGQRCGVEVTSMKAMEDLGRANRR---KPKPPAPEDLAVICFTSGTTGNPKGAMV 288
E + G E+ SM+++E+LG P P P D+A++ +TSG+TG PKG M+
Sbjct: 192 INKAEYPE--GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 249
Query: 289 THRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDI 348
H N+++ + E P DT I +LPLAH+ E E +G +IG+
Sbjct: 250 HHSNLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 304
Query: 349 RLLMD-----------DLKVLQPTVFPVVPRLLNRMFDRIFG--QANTTLKRWLLDFASK 395
L D D VL+PT+ VP +++R++ + Q +++ L
Sbjct: 305 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 364
Query: 396 RKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFY 455
K +++ G + L + L+F KV++ LGG VR+M++G AP+S F+ C
Sbjct: 365 YKLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIG 422
Query: 456 EGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKG 512
+GYG TE +T D+T G VGAP+ C IKL D +E Y + GE+ + G
Sbjct: 423 QGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGG 482
Query: 513 PNVFQGYLKDPAKTAE--ALDKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYI 568
N+ GY K+ KTAE ++D++G W TGDIG++ P+G L+IIDRKK + KL GEY+
Sbjct: 483 QNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYV 542
Query: 569 APEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNK 628
+ K+E + + +S Q+++I+ VVP+ + L AQ++G EG++ ++C N
Sbjct: 543 SLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNP 602
Query: 629 DVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQ 688
++ IL+++ L+ FE + L PE ++ + GL+T K KR ELRN++
Sbjct: 603 AMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKD 662
Query: 689 IDDLY 693
I+ +Y
Sbjct: 663 IERMY 667
>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
2 [Homo sapiens]
Length = 711
Score = 310 bits (795), Expect = 2e-84
Identities = 199/605 (32%), Positives = 316/605 (52%), Gaps = 48/605 (7%)
Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177
Y+W++Y +V GS L G K P I IF + R EW+I Q CF Y+ +V L
Sbjct: 123 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKL------IPGLKIIVVMDAYG 231
Y TLG EA+ + +N++E S + +E +E+KL I +K I+ +D
Sbjct: 181 YATLGKEAVVHGLNESEASYLITS--------VELLESKLKTALLDISCVKHIIYVDNKA 232
Query: 232 SELVERGQRCGVEVTSMKAMEDLGRANRR---KPKPPAPEDLAVICFTSGTTGNPKGAMV 288
E + G E+ SM+++E+LG P P P D+A++ +TSG+TG PKG M+
Sbjct: 233 INKAEYPE--GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 290
Query: 289 THRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDI 348
H N+++ + E P DT I +LPLAH+ E E +G +IG+
Sbjct: 291 HHSNLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 345
Query: 349 RLLMD-----------DLKVLQPTVFPVVPRLLNRMFDRIFG--QANTTLKRWLLDFASK 395
L D D VL+PT+ VP +++R++ + Q +++ L
Sbjct: 346 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 405
Query: 396 RKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFY 455
K +++ G + L + L+F KV++ LGG VR+M++G AP+S F+ C
Sbjct: 406 YKLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIG 463
Query: 456 EGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKG 512
+GYG TE +T D+T G VGAP+ C IKL D +E Y + GE+ + G
Sbjct: 464 QGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGG 523
Query: 513 PNVFQGYLKDPAKTAE--ALDKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYI 568
N+ GY K+ KTAE ++D++G W TGDIG++ P+G L+IIDRKK + KL GEY+
Sbjct: 524 QNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYV 583
Query: 569 APEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNK 628
+ K+E + + +S Q+++I+ VVP+ + L AQ++G EG++ ++C N
Sbjct: 584 SLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNP 643
Query: 629 DVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQ 688
++ IL+++ L+ FE + L PE ++ + GL+T K KR ELRN++
Sbjct: 644 AMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKD 703
Query: 689 IDDLY 693
I+ +Y
Sbjct: 704 IERMY 708
>gi|27477105 lipidosin [Homo sapiens]
Length = 724
Score = 181 bits (458), Expect = 3e-45
Identities = 173/641 (26%), Positives = 287/641 (44%), Gaps = 53/641 (8%)
Query: 91 TLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKTAPDQFI 150
T++ F + + LG ++ D+ +E +SY Q L+ ++ G K A +
Sbjct: 104 TVHRMFYEALDKYGDLIALGFKRQDK-WEHISYSQYYLLARRAAKGFLKLGLKQAHS--V 160
Query: 151 GIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLL 210
I N PEW G ++ +Y T EA YI +++ VD ++ + +L
Sbjct: 161 AILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKIL 220
Query: 211 EGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKP-----KPP 265
+ K +P LK +V+ E V +M+ +LG +
Sbjct: 221 KIW--KQLPHLKAVVIYK-------EPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQ 271
Query: 266 APEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHM 325
P V+ +TSGTTGNPKG M++ NI +A + + ++S+LPL+H+
Sbjct: 272 QPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHI 331
Query: 326 FERVVEC-VMLCHGAKIGFFQGDIRL--LMDDLKVLQPTVFPVVPRLLNRMFDRI---FG 379
++ + + GA++ F + D L++ L+ ++PT VPR+ ++ +RI
Sbjct: 332 AAQIYDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAA 391
Query: 380 QANTTLKRWLLDFASKRKEAELR--SGIIR--NNSLWDRLIFHKVQSSLG-GRVRLMVTG 434
Q+ ++ LL S E L ++ L D L+ KV+ +LG + + G
Sbjct: 392 QSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYG 451
Query: 435 AAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDV 494
AAP+ A F L + Y GYG +E + ++ P ++ G +P +KLV+
Sbjct: 452 AAPMMAETQHFF-LGLNIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQ 510
Query: 495 EEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIID 554
+ AEG GE+C+ G +F GYL KT EA+D++GWLHTGD G+ +G L I
Sbjct: 511 D------AEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITG 564
Query: 555 RKKHIFKLAQGEYIAPEKIEN-IYMRSEPVAQVFVHGE-----SLQAFLIAIVVPD---- 604
R K + A GE + P IE + M ++ + G+ S+ L + PD
Sbjct: 565 RLKELIITAGGENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQ 624
Query: 605 ----VETLCSWAQKRGFEG-SFEELCRNKD--VKKAILEDMVRLGKDSGLKPFEQVKGIT 657
E + Q+ G + E+ KD V +AI E + R+ ++ +P+ K
Sbjct: 625 TDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAI 684
Query: 658 LHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV 698
L + FSI G L PTMK KR + ++ ID Y K+
Sbjct: 685 LERD-FSISGGELGPTMKLKRLTVLEKYKGIIDSFYQEQKM 724
>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
Length = 666
Score = 155 bits (392), Expect = 1e-37
Identities = 157/641 (24%), Positives = 293/641 (45%), Gaps = 65/641 (10%)
Query: 91 TLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKTAPDQFI 150
T+ E F+ + P L S K + +E L++ Q E +LI+ G + +
Sbjct: 52 TIPEFFRESVNRFGTYPALAS-KNGKKWEILNFNQYYEACRKAAKSLIKLGLERFHG--V 108
Query: 151 GIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLL 210
GI N EW I G + V +Y T E Y++ A+++++ V+ ++ + +L
Sbjct: 109 GILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVENDQQLQKIL 168
Query: 211 EGVENKLIPGLKIIVVM--------DAYG-SELVERGQRCGVEVTSMKAMEDLGRANRRK 261
++ L P LK I+ + Y + +E G+ + T ++ + + +AN+
Sbjct: 169 SIPQSSLEP-LKAIIQYRLPMKKNNNLYSWDDFMELGR--SIPDTQLEQVIESQKANQ-- 223
Query: 262 PKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLP 321
AV+ +TSGTTG PKG M++H NI A K + T +T++S+LP
Sbjct: 224 --------CAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKLTDK---HETVVSYLP 272
Query: 322 LAHMFERVVEC-VMLCHGAKIGFFQGDIR--LLMDDLKVLQPTVFPVVPRLLNRMFDRIF 378
L+H+ ++++ V + GA F Q D L+ LK ++PTVF VP++ ++ + +
Sbjct: 273 LSHIAAQMMDIWVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVK 332
Query: 379 GQANTT--LKR----WLLDFASKRKEAEL--RSGIIRNNSLWDRLIFHKVQSSLG-GRVR 429
+ + LK+ W + K ++ + + + L+F KV++SLG
Sbjct: 333 KNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCH 392
Query: 430 LMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLI 489
++G AP++ F +L E YG +E + ++ ++ + C I
Sbjct: 393 SFISGTAPLNQETAEFF-LSLDIPIGELYGLSESSGPHTISNQNNYRL------LSCGKI 445
Query: 490 KLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGT 549
+ +G GE+C+ G ++F GYL+ +T EA+D +GWLH+GD+G+ G
Sbjct: 446 LTGCKNMLFQQNKDGIGEICLWGRHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLGF 505
Query: 550 LKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEP-VAQVFVHGESLQ--AFLIAIVVPDVE 606
L + K I A GE + P +E + + P ++ + G+ L+ + L+ + +
Sbjct: 506 LYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISNAMLVGDKLKFLSMLLTLKCEMNQ 565
Query: 607 TLCSWAQKRGFE------------GSFEELCRNKD--VKKAILEDMVRLGKDSGLKPFEQ 652
K FE + E+ + +D V KAI + + + +++ + ++
Sbjct: 566 MSGEPLDKLNFEAINFCRGLGSQASTVTEIVKQQDPLVYKAIQQGINAVNQEA-MNNAQR 624
Query: 653 VKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLY 693
++ + + FSI G L P MK KR + ++ QID +Y
Sbjct: 625 IEKWVILEKDFSIYGGELGPMMKLKRHFVAQKYKKQIDHMY 665
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 81.6 bits (200), Expect = 2e-15
Identities = 110/452 (24%), Positives = 178/452 (39%), Gaps = 109/452 (24%)
Query: 124 KQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGN 183
+++ L C+G L ++ + N +V+ + + V VPLY
Sbjct: 80 QEICRLCGCVGGDL--------REERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA 131
Query: 184 EAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGV 243
+ Y++ ++ S+V ++ LL V KL G+ ++ + A + VE V
Sbjct: 132 AQLEYVICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLLPLTPAIYTGAVEEPAEVPV 187
Query: 244 EVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKA 303
+ G N+ A+I +TSGTTG PKG + TH+NI + + V
Sbjct: 188 P--------EQGWRNKG----------AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHK 229
Query: 304 TENTVNPCPDDTLISFLPLAHMFERV----------VECVMLCHGAKIGFFQGDIRLLMD 353
T DD ++ LPL H+ V CVM+ + ++ + L
Sbjct: 230 WAWT----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWE---KFLSS 282
Query: 354 DLKVLQPTVFPVVPRLLNRM---FDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNS 410
+ + VF VP + ++ +DR F Q + DF
Sbjct: 283 ETPRIN--VFMAVPTIYTKLMEYYDRHFTQPHAQ------DF------------------ 316
Query: 411 LWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLT 470
+++ ++RLMV+G+A + VL + G E YG TE G L+
Sbjct: 317 ---------LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI--GMALS 365
Query: 471 MPGDWTA---GHVGAPMPCNLIKLVDV----EEMNY-MAAEG--------------EGEV 508
P G VG P+P +++V E +Y + AEG EGE+
Sbjct: 366 GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGEL 425
Query: 509 CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
V+GP+VF+ Y P +T A DGW TGD
Sbjct: 426 LVRGPSVFREYWNKPEETKSAFTLDGWFKTGD 457
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 81.6 bits (200), Expect = 2e-15
Identities = 110/452 (24%), Positives = 178/452 (39%), Gaps = 109/452 (24%)
Query: 124 KQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGN 183
+++ L C+G L ++ + N +V+ + + V VPLY
Sbjct: 80 QEICRLCGCVGGDL--------REERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA 131
Query: 184 EAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGV 243
+ Y++ ++ S+V ++ LL V KL G+ ++ + A + VE V
Sbjct: 132 AQLEYVICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLLPLTPAIYTGAVEEPAEVPV 187
Query: 244 EVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKA 303
+ G N+ A+I +TSGTTG PKG + TH+NI + + V
Sbjct: 188 P--------EQGWRNKG----------AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHK 229
Query: 304 TENTVNPCPDDTLISFLPLAHMFERV----------VECVMLCHGAKIGFFQGDIRLLMD 353
T DD ++ LPL H+ V CVM+ + ++ + L
Sbjct: 230 WAWT----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWE---KFLSS 282
Query: 354 DLKVLQPTVFPVVPRLLNRM---FDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNS 410
+ + VF VP + ++ +DR F Q + DF
Sbjct: 283 ETPRIN--VFMAVPTIYTKLMEYYDRHFTQPHAQ------DF------------------ 316
Query: 411 LWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLT 470
+++ ++RLMV+G+A + VL + G E YG TE G L+
Sbjct: 317 ---------LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI--GMALS 365
Query: 471 MPGDWTA---GHVGAPMPCNLIKLVDV----EEMNY-MAAEG--------------EGEV 508
P G VG P+P +++V E +Y + AEG EGE+
Sbjct: 366 GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGEL 425
Query: 509 CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
V+GP+VF+ Y P +T A DGW TGD
Sbjct: 426 LVRGPSVFREYWNKPEETKSAFTLDGWFKTGD 457
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 79.3 bits (194), Expect = 1e-14
Identities = 108/491 (21%), Positives = 190/491 (38%), Gaps = 69/491 (14%)
Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180
L++ Q+ E + S L+ G +G++ N WV+++ +++V +
Sbjct: 100 LTFAQLKEEVDKAASGLLSIGL--CKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157
Query: 181 LGNEAITYIVNKAELSLVFVDKPEKA-------KLLLEGVEN--------KLIPGLKIIV 225
+ Y++ K + K K K + VEN + +P L ++
Sbjct: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217
Query: 226 VMDAY--GSELVERGQRCGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNP 283
+DA G+ L++ G S + D + N++ P ++ FTSGTTG+P
Sbjct: 218 SVDAPLPGTLLLDEVVAAG----STRQHLDQLQYNQQFLSCHDPINIQ---FTSGTTGSP 270
Query: 284 KGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVM-LCHGAKIG 342
KGA ++H NIV++ + + + +I PL H V +M L +GA +
Sbjct: 271 KGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATL- 329
Query: 343 FFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELR 402
+L +F + + I + T L F + +
Sbjct: 330 --------------ILASPIFNG-----KKALEAISRERGTFLYGTPTMFVDILNQPDFS 370
Query: 403 SGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTE 462
S + + + GG ++ G+ + + YG TE
Sbjct: 371 S--------------YDISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTE 412
Query: 463 CTAGCCLTMPGDWT---AGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGY 519
+ P D A VG MP +++++E GE+C++G V GY
Sbjct: 413 NSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGY 472
Query: 520 LKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMR 579
+P KT EA+D+D W TGD+ G KI+ R K + + GE I P ++E+ +
Sbjct: 473 WGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMI-IRGGENIYPAELEDFFHT 531
Query: 580 SEPVAQVFVHG 590
V +V V G
Sbjct: 532 HPKVQEVQVVG 542
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 60.5 bits (145), Expect = 5e-09
Identities = 53/179 (29%), Positives = 81/179 (45%), Gaps = 15/179 (8%)
Query: 432 VTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKL 491
V+ P++ V R G YEGYGQTE C G +G P P +K+
Sbjct: 350 VSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKI 409
Query: 492 VDVEEMNYMAAEGEGEVCVKG-PN----VFQGYLKDPAKTAEALDKDGWLHTGDIGKWLP 546
VDV N + EG++ ++ PN +F Y+ +P+KTA L + + TGD G
Sbjct: 410 VDVNG-NVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTL-RGNFYITGDRGYMDK 467
Query: 547 NGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFV-------HGESLQAFLI 598
+G + R + L+ G I P ++EN VA+ V GE ++AF++
Sbjct: 468 DGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVV 525
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 60.1 bits (144), Expect = 7e-09
Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 15/164 (9%)
Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEG 506
RA G E YGQTE C ++ G++G C ++++D ++ N + EG
Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVID-DKGNVLPPGTEG 408
Query: 507 EVCVKGP-----NVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFK 561
++ ++ +F GY+++P KTA + D WL GD G +G + + R I
Sbjct: 409 DIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467
Query: 562 LAQGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598
+ G I P ++EN M+ V + V GE ++AF+I
Sbjct: 468 -SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 60.1 bits (144), Expect = 7e-09
Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 15/164 (9%)
Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEG 506
RA G E YGQTE C ++ G++G C ++++D ++ N + EG
Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVID-DKGNVLPPGTEG 408
Query: 507 EVCVKGP-----NVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFK 561
++ ++ +F GY+++P KTA + D WL GD G +G + + R I
Sbjct: 409 DIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467
Query: 562 LAQGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598
+ G I P ++EN M+ V + V GE ++AF+I
Sbjct: 468 -SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 59.7 bits (143), Expect = 9e-09
Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 15/164 (9%)
Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEG 506
RA G E YGQTE C ++ G++G C ++++D ++ N + EG
Sbjct: 350 RAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIID-DKGNVLPPGTEG 408
Query: 507 EVCVKGP-----NVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFK 561
++ ++ +F GY+ +P KTA + D WL GD G +G + + R I
Sbjct: 409 DIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467
Query: 562 LAQGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598
+ G I P ++EN M V + V GE ++AF++
Sbjct: 468 -SSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVV 510
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 57.8 bits (138), Expect = 3e-08
Identities = 50/183 (27%), Positives = 84/183 (45%), Gaps = 15/183 (8%)
Query: 428 VRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCN 487
+R +TG P++ VL R G + YEGYGQTE C + G +G M
Sbjct: 340 LRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPY 399
Query: 488 LIKLVDVEEMNYMAAEGEGEVCVK-GPN----VFQGYLKDPAKTAEALDKDGWLHTGDIG 542
++++D E N + EGE+ ++ P F Y+ +P KTA + D ++ TGD G
Sbjct: 400 DVQIID-ENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYV-TGDRG 457
Query: 543 KWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFV-------HGESLQA 595
+G + R + ++ G I P ++E+ + V + V GE ++A
Sbjct: 458 VMDSDGYFWFVGRADDVI-ISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKA 516
Query: 596 FLI 598
F++
Sbjct: 517 FVV 519
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 47.8 bits (112), Expect = 4e-05
Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 15/183 (8%)
Query: 428 VRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCN 487
+R +TG ++ V + G + YEGYGQ+E C +G +G P
Sbjct: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399
Query: 488 LIKLVDVEEMNYMAAEGEGEVCVK-GPN----VFQGYLKDPAKTAEALDKDGWLHTGDIG 542
+++VD +E N + EG V V+ P F YL +P KTA + D ++ TGD
Sbjct: 400 DVQIVD-DEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYI-TGDRA 457
Query: 543 KWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFV-------HGESLQA 595
+ +G + R + + I P ++E+ V + V GE ++A
Sbjct: 458 RMDKDGYFWFMGRNDDVIN-SSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKA 516
Query: 596 FLI 598
F++
Sbjct: 517 FIV 519
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 47.0 bits (110), Expect = 6e-05
Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 17/162 (10%)
Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYM-AAEGE 505
RA G E YGQTE C ++ G++G C DV+ + ++ +
Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASC-----YDVQVIAFVHGSPRA 404
Query: 506 GEVCVKGPNV--FQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLA 563
G++ G F G+ ++P KTA + D WL GD G +G + + R I +
Sbjct: 405 GDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN-S 462
Query: 564 QGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598
G I P ++EN M+ V + V GE ++AF+I
Sbjct: 463 SGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 47.0 bits (110), Expect = 6e-05
Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 17/162 (10%)
Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYM-AAEGE 505
RA G E YGQTE C ++ G++G C DV+ + ++ +
Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASC-----YDVQVIAFVHGSPRA 404
Query: 506 GEVCVKGPNV--FQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLA 563
G++ G F G+ ++P KTA + D WL GD G +G + + R I +
Sbjct: 405 GDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN-S 462
Query: 564 QGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598
G I P ++EN M+ V + V GE ++AF+I
Sbjct: 463 SGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 46.2 bits (108), Expect = 1e-04
Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 15/160 (9%)
Query: 451 GCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEV-- 508
G YE YGQ+E C G +G P ++++D ++ + + EG +
Sbjct: 360 GLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVID-DKGSILPPNTEGNIGI 418
Query: 509 ---CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQG 565
V+ ++F Y DP KTA+ ++ + +TGD GK G + + R I A G
Sbjct: 419 RIKPVRPVSLFMCYEGDPEKTAK-VECGDFYNTGDRGKMDEEGYICFLGRSDDIIN-ASG 476
Query: 566 EYIAPEKIENIYMRSEPVAQVFV-------HGESLQAFLI 598
I P ++E+ + VA+ V GE ++AF++
Sbjct: 477 YRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIV 516
Score = 38.9 bits (89), Expect = 0.016
Identities = 48/203 (23%), Positives = 76/203 (37%), Gaps = 50/203 (24%)
Query: 110 GSRKPDQPYEWL---------SYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEW 160
G R P+ + W+ S++++ +L+ + + Q D + + PEW
Sbjct: 66 GKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDH-LALMLPRVPEW 124
Query: 161 VIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPG 220
++ GC ++ +P L + I Y + +LS
Sbjct: 125 WLVAVGCMRTGIIFIPATILLKAKDILY---RLQLSKA---------------------- 159
Query: 221 LKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRAN----RRKPKPPAPE-------- 268
K IV +DA SE+ +C T + + D R R K +PE
Sbjct: 160 -KGIVTIDALASEVDSIASQCPSLKTKL-LVSDHSREGWLDFRSLVKSASPEHTCVKSKT 217
Query: 269 -DLAVICFTSGTTGNPKGAMVTH 290
D VI FTSGTTG PK A +H
Sbjct: 218 LDPMVIFFTSGTTGFPKMAKHSH 240
>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
sapiens]
Length = 480
Score = 43.9 bits (102), Expect = 5e-04
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
Query: 408 NNSLWDRLIFHKVQSSLGGR-VRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAG 466
N ++ L+ HK +S + ++ V P+S V+ + YEGYGQTE
Sbjct: 317 NPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLL 376
Query: 467 CCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVK 511
C + +G P+P ++++VD E N + EG + ++
Sbjct: 377 CATSKTIKLKPSSLGKPLPPYIVQIVD-ENSNLLPPGEEGNIAIR 420
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 14/86 (16%)
Query: 254 LGRANRRKPKPPAPEDL---------AVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKAT 304
LG A P P P DL A+ +TSGTTG PK A++TH ++ S + +
Sbjct: 264 LGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVL-QMSKMLSLS 322
Query: 305 ENTVNPCPDDTLISFLPLAHMFERVV 330
T DD + + LPL H+ VV
Sbjct: 323 GATA----DDVVYTVLPLYHVMGLVV 344
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 36.2 bits (82), Expect = 0.11
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 5/62 (8%)
Query: 264 PPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLA 323
P + D + FTSGTTG PK A ++H I+ C F + +D + LPL
Sbjct: 323 PQSITDTCLYIFTSGTTGLPKAARISHLKIL-QCQGFYQ----LCGVHQEDVIYLALPLY 377
Query: 324 HM 325
HM
Sbjct: 378 HM 379
>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
Length = 1098
Score = 34.3 bits (77), Expect = 0.40
Identities = 53/242 (21%), Positives = 88/242 (36%), Gaps = 26/242 (10%)
Query: 150 IGIFAQ---NRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKA 206
IG++ Q + P W++ G VP+ T+ + K L + V+K +
Sbjct: 61 IGLYCQPGIDLPSWIL---GILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQIN 117
Query: 207 KL-----LLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRK 261
K L + + +++ + + V G E + ++ + + +
Sbjct: 118 KFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNE 177
Query: 262 PKPPAPEDL------AVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDT 315
K DL A + TSGTTG PK V H+ IV + F + T +D
Sbjct: 178 EKAEEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDIT----QEDV 233
Query: 316 LISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVL-----QPTVFPVVPRLL 370
L PL V + L GA + ++LL L + + TV P LL
Sbjct: 234 LFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLL 293
Query: 371 NR 372
R
Sbjct: 294 RR 295
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 34.3 bits (77), Expect = 0.40
Identities = 54/228 (23%), Positives = 88/228 (38%), Gaps = 30/228 (13%)
Query: 122 SYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTL 181
+++Q+ E S + + L +G A IF +NR E+V + G + + L
Sbjct: 103 TFRQLDEYSSSVANFLQARGL--ASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNL 160
Query: 182 GNEAITYIVNKAEL-SLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240
+A+ + + + +LVF E A + E V L P L +
Sbjct: 161 RRDALLHCLTTSRARALVFGS--EMASAICE-VHASLDPSLSLFC----------SGSWE 207
Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPE----DLAVICFTSGTTGNPKGAMVTHRNIVSD 296
G S + ++ L + + K P P+ D +TSGTTG PK A+V H
Sbjct: 208 PGAVPPSTEHLDPLLK-DAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRM 266
Query: 297 CSAFVKATENTVNPCPDDTLISFLPLAHMFERVV---ECVMLCHGAKI 341
+ P+D + LPL H +V +C L HG +
Sbjct: 267 AALVYYGFRMR----PNDIVYDCLPLYHSAGNIVGIGQC--LLHGMTV 308
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 33.9 bits (76), Expect = 0.52
Identities = 14/23 (60%), Positives = 18/23 (78%)
Query: 271 AVICFTSGTTGNPKGAMVTHRNI 293
A+ +TSGTTG PK AM+TH+ I
Sbjct: 220 ALYIYTSGTTGLPKAAMITHQRI 242
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,037,550
Number of Sequences: 37866
Number of extensions: 1232583
Number of successful extensions: 2555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2447
Number of HSP's gapped (non-prelim): 63
length of query: 698
length of database: 18,247,518
effective HSP length: 109
effective length of query: 589
effective length of database: 14,120,124
effective search space: 8316753036
effective search space used: 8316753036
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.