Guide to the Human Genome
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Search of human proteins with 40807491

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40807491 acyl-CoA synthetase long-chain family member 1
[Homo sapiens]
         (698 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo...  1419   0.0  
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo...  1004   0.0  
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo...   994   0.0  
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo...   876   0.0  
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo...   876   0.0  
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo...   876   0.0  
gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo...   323   3e-88
gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo...   323   3e-88
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor...   310   2e-84
gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo...   310   2e-84
gi|27477105 lipidosin [Homo sapiens]                                  181   3e-45
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]    155   1e-37
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]        82   2e-15
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]        82   2e-15
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]        79   1e-14
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s...    60   5e-09
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [...    60   7e-09
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [...    60   7e-09
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H...    60   9e-09
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H...    58   3e-08
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho...    48   4e-05
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC...    47   6e-05
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC...    47   6e-05
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H...    46   1e-04
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...    44   5e-04
gi|13325057 solute carrier family 27 (fatty acid transporter), m...    42   0.002
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]           36   0.11 
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]     34   0.40 
gi|40807357 solute carrier family 27 (fatty acid transporter), m...    34   0.40 
gi|227499619 solute carrier family 27 (fatty acid transporter), ...    34   0.52 

>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
           sapiens]
          Length = 698

 Score = 1419 bits (3673), Expect = 0.0
 Identities = 698/698 (100%), Positives = 698/698 (100%)

Query: 1   MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60
           MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ
Sbjct: 1   MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60

Query: 61  SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120
           SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW
Sbjct: 61  SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120

Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180
           LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT
Sbjct: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180

Query: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240
           LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR
Sbjct: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240

Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300
           CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF
Sbjct: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300

Query: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360
           VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP
Sbjct: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360

Query: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420
           TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV
Sbjct: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420

Query: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480
           QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV
Sbjct: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480

Query: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
           GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD
Sbjct: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540

Query: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600
           IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI
Sbjct: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600

Query: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660
           VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP
Sbjct: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660

Query: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV 698
           ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV
Sbjct: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV 698


>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
           b [Homo sapiens]
          Length = 722

 Score = 1004 bits (2596), Expect = 0.0
 Identities = 466/694 (67%), Positives = 570/694 (82%)

Query: 1   MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60
           MQ  E+ R  R+PEL D  Q+ R+L   TL+  GA AA+  +W+  RPK L+PPC+L MQ
Sbjct: 26  MQTQEILRILRLPELGDLGQFFRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQ 85

Query: 61  SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120
           S EV  SGGARRS +    + L ++YDD  T+Y+ F+RG+ +S NGPCLG RKP QPY+W
Sbjct: 86  SEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQW 145

Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180
           LSY++VA+ +E +GS L+Q   K   DQFIG+FAQNRPEW+I+E  C+ YSMV+VPLYDT
Sbjct: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205

Query: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240
           LG  AI YI+N A++S V VDKP+KA LLLE VE K  PGLK+I++MD +   L ERGQ+
Sbjct: 206 LGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQK 265

Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300
           CGV + SM+A+ED G+ N + P PP P+DL+++CFTSGTTGNPKGAM+TH N+V+D S F
Sbjct: 266 CGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGF 325

Query: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360
           +K TE  + P  DD LISFLPLAHMFERV++ V+ CHG ++GFFQGDIRLL DD+K L P
Sbjct: 326 LKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCP 385

Query: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420
           T+FPVVPRLLNRM+D+IF QANT LKRWLL+FA+KRK+AE+RSGIIRN+S+WD L F+K+
Sbjct: 386 TIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKI 445

Query: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480
           Q+SLGG VR++VTGAAP S TVL FLRAALGCQ YEGYGQTECTAGC  T PGDWT+GHV
Sbjct: 446 QASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHV 505

Query: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
           GAP+PCN IKLVDVEE+NY A +GEGE+CV+GPNVF+GYLKDP +T EALD DGWLHTGD
Sbjct: 506 GAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGD 565

Query: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600
           IGKWLP GTLKIIDRKKHIFKLAQGEY+APEKIENIY+RS+PVAQ++VHG+SL+AFL+ I
Sbjct: 566 IGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGI 625

Query: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660
           VVPD E + SWAQKRG EG++ +LC NKD+KKAILEDMVRLGK+SGL  FEQVK I +H 
Sbjct: 626 VVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHS 685

Query: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYS 694
           ++FS+ NGLLTPT+KAKRPELR YF+ QI++LYS
Sbjct: 686 DMFSVQNGLLTPTLKAKRPELREYFKKQIEELYS 719


>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
           a [Homo sapiens]
          Length = 722

 Score =  994 bits (2571), Expect = 0.0
 Identities = 463/694 (66%), Positives = 568/694 (81%)

Query: 1   MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60
           MQ  E+ R  R+PEL D  Q+ R+L   TL+  GA AA+  +W+  RPK L+PPC+L MQ
Sbjct: 26  MQTQEILRILRLPELGDLGQFFRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQ 85

Query: 61  SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120
           S EV  SGGARRS +    + L ++YDD  T+Y+ F+RG+ +S NGPCLG RKP QPY+W
Sbjct: 86  SEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQW 145

Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180
           LSY++VA+ +E +GS L+Q   K   DQFIG+FAQNRPEW+I+E  C+ YSMV+VPLYDT
Sbjct: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205

Query: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240
           LG  AI YI+N A++S V VDKP+KA LLLE VE K  PGLK+I++MD +   L ERGQ+
Sbjct: 206 LGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQK 265

Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300
           CGV + SM+A+ED G+ N + P PP P+DL+++CFTSGTTGNPKGAM+TH N+V+D S F
Sbjct: 266 CGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGF 325

Query: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360
           +K TE+   P   D  IS+LPLAHMFER+V+ V+ CHG ++GFFQGDIRLL DD+K L P
Sbjct: 326 LKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCP 385

Query: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420
           T+FPVVPRLLNRM+D+IF QANT LKRWLL+FA+KRK+AE+RSGIIRN+S+WD L F+K+
Sbjct: 386 TIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKI 445

Query: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480
           Q+SLGG VR++VTGAAP S TVL FLRAALGCQ YEGYGQTECTAGC  T PGDWT+GHV
Sbjct: 446 QASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHV 505

Query: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
           GAP+PCN IKLVDVEE+NY A +GEGE+CV+GPNVF+GYLKDP +T EALD DGWLHTGD
Sbjct: 506 GAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGD 565

Query: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600
           IGKWLP GTLKIIDRKKHIFKLAQGEY+APEKIENIY+RS+PVAQ++VHG+SL+AFL+ I
Sbjct: 566 IGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGI 625

Query: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660
           VVPD E + SWAQKRG EG++ +LC NKD+KKAILEDMVRLGK+SGL  FEQVK I +H 
Sbjct: 626 VVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHS 685

Query: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYS 694
           ++FS+ NGLLTPT+KAKRPELR YF+ QI++LYS
Sbjct: 686 DMFSVQNGLLTPTLKAKRPELREYFKKQIEELYS 719


>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score =  876 bits (2263), Expect = 0.0
 Identities = 414/673 (61%), Positives = 527/673 (78%), Gaps = 2/673 (0%)

Query: 25  LPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVY 84
           LPT  L+    F A    W  TRP+P+ P  DL+ QSV +   GGAR+     +++    
Sbjct: 12  LPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGI--EGGARKGVSQKNNDLTSC 69

Query: 85  FYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKT 144
            + D  T+YE FQRG+ VS+NGPCLG RKP+QPY WLSYKQV++ +E +GS L+ KG+K+
Sbjct: 70  CFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKS 129

Query: 145 APDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPE 204
           +PDQF+GIFAQNRPEW+I E  C+ YSMV VPLYDTLG EAI +IVNKA++++V  D P+
Sbjct: 130 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 189

Query: 205 KAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKP 264
           KA +L+  VE    P LK+I++MD +  +L +RG++ G+E+ S+   E+LG+ + RKP P
Sbjct: 190 KALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVP 249

Query: 265 PAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAH 324
           P+PEDL+VICFTSGTTG+PKGAM+TH+NIVS+ +AF+K  E+   P PDD  IS+LPLAH
Sbjct: 250 PSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309

Query: 325 MFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTT 384
           MFER+V+ V+   GA++GFFQGDIRLL DD+K L+PT+FP VPRLLNR++D++  +A T 
Sbjct: 310 MFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP 369

Query: 385 LKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLT 444
           LK++LL  A   K  EL+ GIIR++S WD+LIF K+Q SLGGRVR++VTGAAP+S +V+T
Sbjct: 370 LKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMT 429

Query: 445 FLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG 504
           F RAA+GCQ YE YGQTECT GC  T+PGDWT+GHVG P+ CN +KL DV +MNY     
Sbjct: 430 FFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN 489

Query: 505 EGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQ 564
           EGEVC+KG NVF+GYLKDP KT EALD DGWLHTGDIG+WLPNGTLKIIDRKK+IFKLAQ
Sbjct: 490 EGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQ 549

Query: 565 GEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL 624
           GEYIAPEKIENIY RS+PV Q+FVHGESL++ L+ +VVPD + L S+A K G +GSFEEL
Sbjct: 550 GEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEEL 609

Query: 625 CRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNY 684
           C+N+ V++AILED+ ++GK+SGLK FEQVK I LHPE FSI+NGLLTPT+KAKR EL  Y
Sbjct: 610 CQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKY 669

Query: 685 FRSQIDDLYSTIK 697
           FR+QID LY  I+
Sbjct: 670 FRTQIDSLYEHIQ 682


>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score =  876 bits (2263), Expect = 0.0
 Identities = 414/673 (61%), Positives = 527/673 (78%), Gaps = 2/673 (0%)

Query: 25  LPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVY 84
           LPT  L+    F A    W  TRP+P+ P  DL+ QSV +   GGAR+     +++    
Sbjct: 12  LPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGI--EGGARKGVSQKNNDLTSC 69

Query: 85  FYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKT 144
            + D  T+YE FQRG+ VS+NGPCLG RKP+QPY WLSYKQV++ +E +GS L+ KG+K+
Sbjct: 70  CFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKS 129

Query: 145 APDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPE 204
           +PDQF+GIFAQNRPEW+I E  C+ YSMV VPLYDTLG EAI +IVNKA++++V  D P+
Sbjct: 130 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 189

Query: 205 KAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKP 264
           KA +L+  VE    P LK+I++MD +  +L +RG++ G+E+ S+   E+LG+ + RKP P
Sbjct: 190 KALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVP 249

Query: 265 PAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAH 324
           P+PEDL+VICFTSGTTG+PKGAM+TH+NIVS+ +AF+K  E+   P PDD  IS+LPLAH
Sbjct: 250 PSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309

Query: 325 MFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTT 384
           MFER+V+ V+   GA++GFFQGDIRLL DD+K L+PT+FP VPRLLNR++D++  +A T 
Sbjct: 310 MFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP 369

Query: 385 LKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLT 444
           LK++LL  A   K  EL+ GIIR++S WD+LIF K+Q SLGGRVR++VTGAAP+S +V+T
Sbjct: 370 LKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMT 429

Query: 445 FLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG 504
           F RAA+GCQ YE YGQTECT GC  T+PGDWT+GHVG P+ CN +KL DV +MNY     
Sbjct: 430 FFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN 489

Query: 505 EGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQ 564
           EGEVC+KG NVF+GYLKDP KT EALD DGWLHTGDIG+WLPNGTLKIIDRKK+IFKLAQ
Sbjct: 490 EGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQ 549

Query: 565 GEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL 624
           GEYIAPEKIENIY RS+PV Q+FVHGESL++ L+ +VVPD + L S+A K G +GSFEEL
Sbjct: 550 GEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEEL 609

Query: 625 CRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNY 684
           C+N+ V++AILED+ ++GK+SGLK FEQVK I LHPE FSI+NGLLTPT+KAKR EL  Y
Sbjct: 610 CQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKY 669

Query: 685 FRSQIDDLYSTIK 697
           FR+QID LY  I+
Sbjct: 670 FRTQIDSLYEHIQ 682


>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
           a [Homo sapiens]
          Length = 739

 Score =  876 bits (2263), Expect = 0.0
 Identities = 414/673 (61%), Positives = 527/673 (78%), Gaps = 2/673 (0%)

Query: 25  LPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVY 84
           LPT  L+    F A    W  TRP+P+ P  DL+ QSV +   GGAR+     +++    
Sbjct: 68  LPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGI--EGGARKGVSQKNNDLTSC 125

Query: 85  FYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKT 144
            + D  T+YE FQRG+ VS+NGPCLG RKP+QPY WLSYKQV++ +E +GS L+ KG+K+
Sbjct: 126 CFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKS 185

Query: 145 APDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPE 204
           +PDQF+GIFAQNRPEW+I E  C+ YSMV VPLYDTLG EAI +IVNKA++++V  D P+
Sbjct: 186 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 245

Query: 205 KAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKP 264
           KA +L+  VE    P LK+I++MD +  +L +RG++ G+E+ S+   E+LG+ + RKP P
Sbjct: 246 KALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVP 305

Query: 265 PAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAH 324
           P+PEDL+VICFTSGTTG+PKGAM+TH+NIVS+ +AF+K  E+   P PDD  IS+LPLAH
Sbjct: 306 PSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 365

Query: 325 MFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTT 384
           MFER+V+ V+   GA++GFFQGDIRLL DD+K L+PT+FP VPRLLNR++D++  +A T 
Sbjct: 366 MFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP 425

Query: 385 LKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLT 444
           LK++LL  A   K  EL+ GIIR++S WD+LIF K+Q SLGGRVR++VTGAAP+S +V+T
Sbjct: 426 LKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMT 485

Query: 445 FLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG 504
           F RAA+GCQ YE YGQTECT GC  T+PGDWT+GHVG P+ CN +KL DV +MNY     
Sbjct: 486 FFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN 545

Query: 505 EGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQ 564
           EGEVC+KG NVF+GYLKDP KT EALD DGWLHTGDIG+WLPNGTLKIIDRKK+IFKLAQ
Sbjct: 546 EGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQ 605

Query: 565 GEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL 624
           GEYIAPEKIENIY RS+PV Q+FVHGESL++ L+ +VVPD + L S+A K G +GSFEEL
Sbjct: 606 GEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEEL 665

Query: 625 CRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNY 684
           C+N+ V++AILED+ ++GK+SGLK FEQVK I LHPE FSI+NGLLTPT+KAKR EL  Y
Sbjct: 666 CQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKY 725

Query: 685 FRSQIDDLYSTIK 697
           FR+QID LY  I+
Sbjct: 726 FRTQIDSLYEHIQ 738


>gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo
           sapiens]
          Length = 720

 Score =  323 bits (828), Expect = 3e-88
 Identities = 205/599 (34%), Positives = 321/599 (53%), Gaps = 36/599 (6%)

Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177
           Y WLSY+ V   +   G+ L   G K  P   I IF + R EW+I  Q CF Y+  +V L
Sbjct: 132 YNWLSYEDVFVRAFNFGNGLQMLGQK--PKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189

Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVER 237
           Y TLG  AI + +N+ E++ +   K E  +  L+ + + L+P L+ I+ +D       E 
Sbjct: 190 YATLGGPAIVHALNETEVTNIITSK-ELLQTKLKDIVS-LVPRLRHIITVDGKPPTWSEF 247

Query: 238 GQRCGVEVTSMKAMEDLGRANRRKPKP---PAPEDLAVICFTSGTTGNPKGAMVTHRNIV 294
            +  G+ V +M A+E LG     + +P   P P D+AVI +TSG+TG PKG M++H NI+
Sbjct: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305

Query: 295 SDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMD- 353
           +  +      E       +D  I +LPLAH+ E   E V L HG +IG+     + L D 
Sbjct: 306 AGITGMA---ERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360

Query: 354 ----------DLKVLQPTVFPVVPRLLNRMFDRIFGQAN--TTLKRWLLDFASKRKEAEL 401
                     D  +L+PT+   VP +++R++  +  + +  ++ +R L   A   K  ++
Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420

Query: 402 RSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQT 461
             G  RN  L D  +F KV+S LGG +RL++ G AP+SAT   F+     C   +GYG T
Sbjct: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478

Query: 462 ECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKGPNVFQG 518
           E      ++   D+  G VGAP+ C  IKL + EE  Y   +     GE+ + G +V  G
Sbjct: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538

Query: 519 YLKDPAKTAEAL--DKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIE 574
           Y K+ AKT      D++G  WL TGDIG++ P+G LKIIDRKK + KL  GEY++  K+E
Sbjct: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598

Query: 575 NIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAI 634
                   V  +  +  S  +++I  VVP+ + L   A+K+G +G++EELC + +++  +
Sbjct: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658

Query: 635 LEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLY 693
           L+ +      + L+ FE    I L PE ++ + GL+T   K KR EL+ ++++ I+ +Y
Sbjct: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717


>gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo
           sapiens]
          Length = 720

 Score =  323 bits (828), Expect = 3e-88
 Identities = 205/599 (34%), Positives = 321/599 (53%), Gaps = 36/599 (6%)

Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177
           Y WLSY+ V   +   G+ L   G K  P   I IF + R EW+I  Q CF Y+  +V L
Sbjct: 132 YNWLSYEDVFVRAFNFGNGLQMLGQK--PKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189

Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVER 237
           Y TLG  AI + +N+ E++ +   K E  +  L+ + + L+P L+ I+ +D       E 
Sbjct: 190 YATLGGPAIVHALNETEVTNIITSK-ELLQTKLKDIVS-LVPRLRHIITVDGKPPTWSEF 247

Query: 238 GQRCGVEVTSMKAMEDLGRANRRKPKP---PAPEDLAVICFTSGTTGNPKGAMVTHRNIV 294
            +  G+ V +M A+E LG     + +P   P P D+AVI +TSG+TG PKG M++H NI+
Sbjct: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305

Query: 295 SDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMD- 353
           +  +      E       +D  I +LPLAH+ E   E V L HG +IG+     + L D 
Sbjct: 306 AGITGMA---ERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360

Query: 354 ----------DLKVLQPTVFPVVPRLLNRMFDRIFGQAN--TTLKRWLLDFASKRKEAEL 401
                     D  +L+PT+   VP +++R++  +  + +  ++ +R L   A   K  ++
Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420

Query: 402 RSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQT 461
             G  RN  L D  +F KV+S LGG +RL++ G AP+SAT   F+     C   +GYG T
Sbjct: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478

Query: 462 ECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKGPNVFQG 518
           E      ++   D+  G VGAP+ C  IKL + EE  Y   +     GE+ + G +V  G
Sbjct: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538

Query: 519 YLKDPAKTAEAL--DKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIE 574
           Y K+ AKT      D++G  WL TGDIG++ P+G LKIIDRKK + KL  GEY++  K+E
Sbjct: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598

Query: 575 NIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAI 634
                   V  +  +  S  +++I  VVP+ + L   A+K+G +G++EELC + +++  +
Sbjct: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658

Query: 635 LEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLY 693
           L+ +      + L+ FE    I L PE ++ + GL+T   K KR EL+ ++++ I+ +Y
Sbjct: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717


>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
           [Homo sapiens]
          Length = 670

 Score =  310 bits (795), Expect = 2e-84
 Identities = 199/605 (32%), Positives = 316/605 (52%), Gaps = 48/605 (7%)

Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177
           Y+W++Y +V       GS L   G K  P   I IF + R EW+I  Q CF Y+  +V L
Sbjct: 82  YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139

Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKL------IPGLKIIVVMDAYG 231
           Y TLG EA+ + +N++E S +           +E +E+KL      I  +K I+ +D   
Sbjct: 140 YATLGKEAVVHGLNESEASYLITS--------VELLESKLKTALLDISCVKHIIYVDNKA 191

Query: 232 SELVERGQRCGVEVTSMKAMEDLGRANRR---KPKPPAPEDLAVICFTSGTTGNPKGAMV 288
               E  +  G E+ SM+++E+LG         P  P P D+A++ +TSG+TG PKG M+
Sbjct: 192 INKAEYPE--GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 249

Query: 289 THRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDI 348
            H N+++  +      E      P DT I +LPLAH+ E   E     +G +IG+     
Sbjct: 250 HHSNLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 304

Query: 349 RLLMD-----------DLKVLQPTVFPVVPRLLNRMFDRIFG--QANTTLKRWLLDFASK 395
             L D           D  VL+PT+   VP +++R++  +    Q    +++ L      
Sbjct: 305 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 364

Query: 396 RKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFY 455
            K  +++ G   +  L + L+F KV++ LGG VR+M++G AP+S     F+     C   
Sbjct: 365 YKLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIG 422

Query: 456 EGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKG 512
           +GYG TE      +T   D+T G VGAP+ C  IKL D +E  Y   +     GE+ + G
Sbjct: 423 QGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGG 482

Query: 513 PNVFQGYLKDPAKTAE--ALDKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYI 568
            N+  GY K+  KTAE  ++D++G  W  TGDIG++ P+G L+IIDRKK + KL  GEY+
Sbjct: 483 QNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYV 542

Query: 569 APEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNK 628
           +  K+E        +  +    +S Q+++I+ VVP+ + L   AQ++G EG++ ++C N 
Sbjct: 543 SLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNP 602

Query: 629 DVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQ 688
            ++  IL+++        L+ FE    + L PE ++ + GL+T   K KR ELRN++   
Sbjct: 603 AMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKD 662

Query: 689 IDDLY 693
           I+ +Y
Sbjct: 663 IERMY 667


>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
           2 [Homo sapiens]
          Length = 711

 Score =  310 bits (795), Expect = 2e-84
 Identities = 199/605 (32%), Positives = 316/605 (52%), Gaps = 48/605 (7%)

Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177
           Y+W++Y +V       GS L   G K  P   I IF + R EW+I  Q CF Y+  +V L
Sbjct: 123 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180

Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKL------IPGLKIIVVMDAYG 231
           Y TLG EA+ + +N++E S +           +E +E+KL      I  +K I+ +D   
Sbjct: 181 YATLGKEAVVHGLNESEASYLITS--------VELLESKLKTALLDISCVKHIIYVDNKA 232

Query: 232 SELVERGQRCGVEVTSMKAMEDLGRANRR---KPKPPAPEDLAVICFTSGTTGNPKGAMV 288
               E  +  G E+ SM+++E+LG         P  P P D+A++ +TSG+TG PKG M+
Sbjct: 233 INKAEYPE--GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 290

Query: 289 THRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDI 348
            H N+++  +      E      P DT I +LPLAH+ E   E     +G +IG+     
Sbjct: 291 HHSNLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 345

Query: 349 RLLMD-----------DLKVLQPTVFPVVPRLLNRMFDRIFG--QANTTLKRWLLDFASK 395
             L D           D  VL+PT+   VP +++R++  +    Q    +++ L      
Sbjct: 346 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 405

Query: 396 RKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFY 455
            K  +++ G   +  L + L+F KV++ LGG VR+M++G AP+S     F+     C   
Sbjct: 406 YKLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIG 463

Query: 456 EGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKG 512
           +GYG TE      +T   D+T G VGAP+ C  IKL D +E  Y   +     GE+ + G
Sbjct: 464 QGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGG 523

Query: 513 PNVFQGYLKDPAKTAE--ALDKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYI 568
            N+  GY K+  KTAE  ++D++G  W  TGDIG++ P+G L+IIDRKK + KL  GEY+
Sbjct: 524 QNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYV 583

Query: 569 APEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNK 628
           +  K+E        +  +    +S Q+++I+ VVP+ + L   AQ++G EG++ ++C N 
Sbjct: 584 SLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNP 643

Query: 629 DVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQ 688
            ++  IL+++        L+ FE    + L PE ++ + GL+T   K KR ELRN++   
Sbjct: 644 AMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKD 703

Query: 689 IDDLY 693
           I+ +Y
Sbjct: 704 IERMY 708


>gi|27477105 lipidosin [Homo sapiens]
          Length = 724

 Score =  181 bits (458), Expect = 3e-45
 Identities = 173/641 (26%), Positives = 287/641 (44%), Gaps = 53/641 (8%)

Query: 91  TLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKTAPDQFI 150
           T++  F   +    +   LG ++ D+ +E +SY Q   L+       ++ G K A    +
Sbjct: 104 TVHRMFYEALDKYGDLIALGFKRQDK-WEHISYSQYYLLARRAAKGFLKLGLKQAHS--V 160

Query: 151 GIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLL 210
            I   N PEW     G      ++  +Y T   EA  YI      +++ VD  ++ + +L
Sbjct: 161 AILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKIL 220

Query: 211 EGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKP-----KPP 265
           +    K +P LK +V+         E        V +M+   +LG     +         
Sbjct: 221 KIW--KQLPHLKAVVIYK-------EPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQ 271

Query: 266 APEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHM 325
            P    V+ +TSGTTGNPKG M++  NI        +A +        + ++S+LPL+H+
Sbjct: 272 QPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHI 331

Query: 326 FERVVEC-VMLCHGAKIGFFQGDIRL--LMDDLKVLQPTVFPVVPRLLNRMFDRI---FG 379
             ++ +    +  GA++ F + D     L++ L+ ++PT    VPR+  ++ +RI     
Sbjct: 332 AAQIYDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAA 391

Query: 380 QANTTLKRWLLDFASKRKEAELR--SGIIR--NNSLWDRLIFHKVQSSLG-GRVRLMVTG 434
           Q+    ++ LL   S   E  L      ++     L D L+  KV+ +LG  + +    G
Sbjct: 392 QSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYG 451

Query: 435 AAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDV 494
           AAP+ A    F    L  + Y GYG +E +    ++ P ++     G  +P   +KLV+ 
Sbjct: 452 AAPMMAETQHFF-LGLNIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQ 510

Query: 495 EEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIID 554
           +      AEG GE+C+ G  +F GYL    KT EA+D++GWLHTGD G+   +G L I  
Sbjct: 511 D------AEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITG 564

Query: 555 RKKHIFKLAQGEYIAPEKIEN-IYMRSEPVAQVFVHGE-----SLQAFLIAIVVPD---- 604
           R K +   A GE + P  IE  + M    ++   + G+     S+   L   + PD    
Sbjct: 565 RLKELIITAGGENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQ 624

Query: 605 ----VETLCSWAQKRGFEG-SFEELCRNKD--VKKAILEDMVRLGKDSGLKPFEQVKGIT 657
                E    + Q+ G    +  E+   KD  V +AI E + R+  ++  +P+   K   
Sbjct: 625 TDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAI 684

Query: 658 LHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV 698
           L  + FSI  G L PTMK KR  +   ++  ID  Y   K+
Sbjct: 685 LERD-FSISGGELGPTMKLKRLTVLEKYKGIIDSFYQEQKM 724


>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
          Length = 666

 Score =  155 bits (392), Expect = 1e-37
 Identities = 157/641 (24%), Positives = 293/641 (45%), Gaps = 65/641 (10%)

Query: 91  TLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKTAPDQFI 150
           T+ E F+  +      P L S K  + +E L++ Q  E       +LI+ G +      +
Sbjct: 52  TIPEFFRESVNRFGTYPALAS-KNGKKWEILNFNQYYEACRKAAKSLIKLGLERFHG--V 108

Query: 151 GIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLL 210
           GI   N  EW I   G      + V +Y T   E   Y++  A+++++ V+  ++ + +L
Sbjct: 109 GILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVENDQQLQKIL 168

Query: 211 EGVENKLIPGLKIIVVM--------DAYG-SELVERGQRCGVEVTSMKAMEDLGRANRRK 261
              ++ L P LK I+          + Y   + +E G+   +  T ++ + +  +AN+  
Sbjct: 169 SIPQSSLEP-LKAIIQYRLPMKKNNNLYSWDDFMELGR--SIPDTQLEQVIESQKANQ-- 223

Query: 262 PKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLP 321
                    AV+ +TSGTTG PKG M++H NI     A  K  + T      +T++S+LP
Sbjct: 224 --------CAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKLTDK---HETVVSYLP 272

Query: 322 LAHMFERVVEC-VMLCHGAKIGFFQGDIR--LLMDDLKVLQPTVFPVVPRLLNRMFDRIF 378
           L+H+  ++++  V +  GA   F Q D     L+  LK ++PTVF  VP++  ++ + + 
Sbjct: 273 LSHIAAQMMDIWVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVK 332

Query: 379 GQANTT--LKR----WLLDFASKRKEAEL--RSGIIRNNSLWDRLIFHKVQSSLG-GRVR 429
             +  +  LK+    W  +   K    ++  +     +  +   L+F KV++SLG     
Sbjct: 333 KNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCH 392

Query: 430 LMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLI 489
             ++G AP++     F   +L     E YG +E +    ++   ++        + C  I
Sbjct: 393 SFISGTAPLNQETAEFF-LSLDIPIGELYGLSESSGPHTISNQNNYRL------LSCGKI 445

Query: 490 KLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGT 549
                  +     +G GE+C+ G ++F GYL+   +T EA+D +GWLH+GD+G+    G 
Sbjct: 446 LTGCKNMLFQQNKDGIGEICLWGRHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLGF 505

Query: 550 LKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEP-VAQVFVHGESLQ--AFLIAIVVPDVE 606
           L +    K I   A GE + P  +E +  +  P ++   + G+ L+  + L+ +     +
Sbjct: 506 LYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISNAMLVGDKLKFLSMLLTLKCEMNQ 565

Query: 607 TLCSWAQKRGFE------------GSFEELCRNKD--VKKAILEDMVRLGKDSGLKPFEQ 652
                  K  FE             +  E+ + +D  V KAI + +  + +++ +   ++
Sbjct: 566 MSGEPLDKLNFEAINFCRGLGSQASTVTEIVKQQDPLVYKAIQQGINAVNQEA-MNNAQR 624

Query: 653 VKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLY 693
           ++   +  + FSI  G L P MK KR  +   ++ QID +Y
Sbjct: 625 IEKWVILEKDFSIYGGELGPMMKLKRHFVAQKYKKQIDHMY 665


>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 110/452 (24%), Positives = 178/452 (39%), Gaps = 109/452 (24%)

Query: 124 KQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGN 183
           +++  L  C+G  L         ++ +     N   +V+ +   +    V VPLY     
Sbjct: 80  QEICRLCGCVGGDL--------REERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA 131

Query: 184 EAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGV 243
             + Y++  ++ S+V     ++   LL  V  KL  G+ ++ +  A  +  VE      V
Sbjct: 132 AQLEYVICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLLPLTPAIYTGAVEEPAEVPV 187

Query: 244 EVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKA 303
                    + G  N+           A+I +TSGTTG PKG + TH+NI +  +  V  
Sbjct: 188 P--------EQGWRNKG----------AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHK 229

Query: 304 TENTVNPCPDDTLISFLPLAHMFERV----------VECVMLCHGAKIGFFQGDIRLLMD 353
              T     DD ++  LPL H+   V            CVM+   +    ++   + L  
Sbjct: 230 WAWT----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWE---KFLSS 282

Query: 354 DLKVLQPTVFPVVPRLLNRM---FDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNS 410
           +   +   VF  VP +  ++   +DR F Q +        DF                  
Sbjct: 283 ETPRIN--VFMAVPTIYTKLMEYYDRHFTQPHAQ------DF------------------ 316

Query: 411 LWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLT 470
                    +++    ++RLMV+G+A +   VL   +   G    E YG TE   G  L+
Sbjct: 317 ---------LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI--GMALS 365

Query: 471 MPGDWTA---GHVGAPMPCNLIKLVDV----EEMNY-MAAEG--------------EGEV 508
            P        G VG P+P   +++V      E  +Y + AEG              EGE+
Sbjct: 366 GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGEL 425

Query: 509 CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
            V+GP+VF+ Y   P +T  A   DGW  TGD
Sbjct: 426 LVRGPSVFREYWNKPEETKSAFTLDGWFKTGD 457


>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 110/452 (24%), Positives = 178/452 (39%), Gaps = 109/452 (24%)

Query: 124 KQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGN 183
           +++  L  C+G  L         ++ +     N   +V+ +   +    V VPLY     
Sbjct: 80  QEICRLCGCVGGDL--------REERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA 131

Query: 184 EAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGV 243
             + Y++  ++ S+V     ++   LL  V  KL  G+ ++ +  A  +  VE      V
Sbjct: 132 AQLEYVICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLLPLTPAIYTGAVEEPAEVPV 187

Query: 244 EVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKA 303
                    + G  N+           A+I +TSGTTG PKG + TH+NI +  +  V  
Sbjct: 188 P--------EQGWRNKG----------AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHK 229

Query: 304 TENTVNPCPDDTLISFLPLAHMFERV----------VECVMLCHGAKIGFFQGDIRLLMD 353
              T     DD ++  LPL H+   V            CVM+   +    ++   + L  
Sbjct: 230 WAWT----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWE---KFLSS 282

Query: 354 DLKVLQPTVFPVVPRLLNRM---FDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNS 410
           +   +   VF  VP +  ++   +DR F Q +        DF                  
Sbjct: 283 ETPRIN--VFMAVPTIYTKLMEYYDRHFTQPHAQ------DF------------------ 316

Query: 411 LWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLT 470
                    +++    ++RLMV+G+A +   VL   +   G    E YG TE   G  L+
Sbjct: 317 ---------LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI--GMALS 365

Query: 471 MPGDWTA---GHVGAPMPCNLIKLVDV----EEMNY-MAAEG--------------EGEV 508
            P        G VG P+P   +++V      E  +Y + AEG              EGE+
Sbjct: 366 GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGEL 425

Query: 509 CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
            V+GP+VF+ Y   P +T  A   DGW  TGD
Sbjct: 426 LVRGPSVFREYWNKPEETKSAFTLDGWFKTGD 457


>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
          Length = 615

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 108/491 (21%), Positives = 190/491 (38%), Gaps = 69/491 (14%)

Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180
           L++ Q+ E  +   S L+  G        +G++  N   WV+++       +++V +   
Sbjct: 100 LTFAQLKEEVDKAASGLLSIGL--CKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157

Query: 181 LGNEAITYIVNKAELSLVFVDKPEKA-------KLLLEGVEN--------KLIPGLKIIV 225
                + Y++ K     +   K  K        K +   VEN        + +P L  ++
Sbjct: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217

Query: 226 VMDAY--GSELVERGQRCGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNP 283
            +DA   G+ L++     G    S +   D  + N++      P ++    FTSGTTG+P
Sbjct: 218 SVDAPLPGTLLLDEVVAAG----STRQHLDQLQYNQQFLSCHDPINIQ---FTSGTTGSP 270

Query: 284 KGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVM-LCHGAKIG 342
           KGA ++H NIV++ +   +  +          +I   PL H    V   +M L +GA + 
Sbjct: 271 KGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATL- 329

Query: 343 FFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELR 402
                         +L   +F        +  + I  +  T L      F     + +  
Sbjct: 330 --------------ILASPIFNG-----KKALEAISRERGTFLYGTPTMFVDILNQPDFS 370

Query: 403 SGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTE 462
           S              + + +  GG    ++ G+      +   +           YG TE
Sbjct: 371 S--------------YDISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTE 412

Query: 463 CTAGCCLTMPGDWT---AGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGY 519
            +       P D     A  VG  MP    +++++E          GE+C++G  V  GY
Sbjct: 413 NSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGY 472

Query: 520 LKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMR 579
             +P KT EA+D+D W  TGD+      G  KI+ R K +  +  GE I P ++E+ +  
Sbjct: 473 WGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMI-IRGGENIYPAELEDFFHT 531

Query: 580 SEPVAQVFVHG 590
              V +V V G
Sbjct: 532 HPKVQEVQVVG 542


>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
           sapiens]
          Length = 586

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 53/179 (29%), Positives = 81/179 (45%), Gaps = 15/179 (8%)

Query: 432 VTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKL 491
           V+   P++  V    R   G   YEGYGQTE    C          G +G P P   +K+
Sbjct: 350 VSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKI 409

Query: 492 VDVEEMNYMAAEGEGEVCVKG-PN----VFQGYLKDPAKTAEALDKDGWLHTGDIGKWLP 546
           VDV   N +    EG++ ++  PN    +F  Y+ +P+KTA  L +  +  TGD G    
Sbjct: 410 VDVNG-NVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTL-RGNFYITGDRGYMDK 467

Query: 547 NGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFV-------HGESLQAFLI 598
           +G    + R   +  L+ G  I P ++EN       VA+  V        GE ++AF++
Sbjct: 468 DGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVV 525


>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 15/164 (9%)

Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEG 506
           RA  G    E YGQTE    C ++       G++G    C  ++++D ++ N +    EG
Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVID-DKGNVLPPGTEG 408

Query: 507 EVCVKGP-----NVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFK 561
           ++ ++        +F GY+++P KTA  +  D WL  GD G    +G  + + R   I  
Sbjct: 409 DIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467

Query: 562 LAQGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598
            + G  I P ++EN  M+   V +         V GE ++AF+I
Sbjct: 468 -SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510


>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 15/164 (9%)

Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEG 506
           RA  G    E YGQTE    C ++       G++G    C  ++++D ++ N +    EG
Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVID-DKGNVLPPGTEG 408

Query: 507 EVCVKGP-----NVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFK 561
           ++ ++        +F GY+++P KTA  +  D WL  GD G    +G  + + R   I  
Sbjct: 409 DIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467

Query: 562 LAQGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598
            + G  I P ++EN  M+   V +         V GE ++AF+I
Sbjct: 468 -SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510


>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
           sapiens]
          Length = 577

 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 15/164 (9%)

Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEG 506
           RA  G    E YGQTE    C ++       G++G    C  ++++D ++ N +    EG
Sbjct: 350 RAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIID-DKGNVLPPGTEG 408

Query: 507 EVCVKGP-----NVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFK 561
           ++ ++        +F GY+ +P KTA  +  D WL  GD G    +G  + + R   I  
Sbjct: 409 DIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467

Query: 562 LAQGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598
            + G  I P ++EN  M    V +         V GE ++AF++
Sbjct: 468 -SSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVV 510


>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
           sapiens]
          Length = 580

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 50/183 (27%), Positives = 84/183 (45%), Gaps = 15/183 (8%)

Query: 428 VRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCN 487
           +R  +TG  P++  VL   R   G + YEGYGQTE    C      +   G +G  M   
Sbjct: 340 LRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPY 399

Query: 488 LIKLVDVEEMNYMAAEGEGEVCVK-GPN----VFQGYLKDPAKTAEALDKDGWLHTGDIG 542
            ++++D E  N +    EGE+ ++  P      F  Y+ +P KTA  +  D ++ TGD G
Sbjct: 400 DVQIID-ENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYV-TGDRG 457

Query: 543 KWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFV-------HGESLQA 595
               +G    + R   +  ++ G  I P ++E+  +    V +  V        GE ++A
Sbjct: 458 VMDSDGYFWFVGRADDVI-ISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKA 516

Query: 596 FLI 598
           F++
Sbjct: 517 FVV 519


>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
           sapiens]
          Length = 579

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 15/183 (8%)

Query: 428 VRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCN 487
           +R  +TG   ++  V    +   G + YEGYGQ+E    C         +G +G   P  
Sbjct: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399

Query: 488 LIKLVDVEEMNYMAAEGEGEVCVK-GPN----VFQGYLKDPAKTAEALDKDGWLHTGDIG 542
            +++VD +E N +    EG V V+  P      F  YL +P KTA +   D ++ TGD  
Sbjct: 400 DVQIVD-DEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYI-TGDRA 457

Query: 543 KWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFV-------HGESLQA 595
           +   +G    + R   +   +    I P ++E+       V +  V        GE ++A
Sbjct: 458 RMDKDGYFWFMGRNDDVIN-SSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKA 516

Query: 596 FLI 598
           F++
Sbjct: 517 FIV 519


>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 2 [Homo sapiens]
          Length = 571

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 17/162 (10%)

Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYM-AAEGE 505
           RA  G    E YGQTE    C ++       G++G    C      DV+ + ++  +   
Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASC-----YDVQVIAFVHGSPRA 404

Query: 506 GEVCVKGPNV--FQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLA 563
           G++   G     F G+ ++P KTA  +  D WL  GD G    +G  + + R   I   +
Sbjct: 405 GDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN-S 462

Query: 564 QGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598
            G  I P ++EN  M+   V +         V GE ++AF+I
Sbjct: 463 SGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504


>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 1 [Homo sapiens]
          Length = 571

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 17/162 (10%)

Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYM-AAEGE 505
           RA  G    E YGQTE    C ++       G++G    C      DV+ + ++  +   
Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASC-----YDVQVIAFVHGSPRA 404

Query: 506 GEVCVKGPNV--FQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLA 563
           G++   G     F G+ ++P KTA  +  D WL  GD G    +G  + + R   I   +
Sbjct: 405 GDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN-S 462

Query: 564 QGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598
            G  I P ++EN  M+   V +         V GE ++AF+I
Sbjct: 463 SGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504


>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
           sapiens]
          Length = 577

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 15/160 (9%)

Query: 451 GCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEV-- 508
           G   YE YGQ+E    C          G +G   P   ++++D ++ + +    EG +  
Sbjct: 360 GLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVID-DKGSILPPNTEGNIGI 418

Query: 509 ---CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQG 565
               V+  ++F  Y  DP KTA+ ++   + +TGD GK    G +  + R   I   A G
Sbjct: 419 RIKPVRPVSLFMCYEGDPEKTAK-VECGDFYNTGDRGKMDEEGYICFLGRSDDIIN-ASG 476

Query: 566 EYIAPEKIENIYMRSEPVAQVFV-------HGESLQAFLI 598
             I P ++E+  +    VA+  V        GE ++AF++
Sbjct: 477 YRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIV 516



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 48/203 (23%), Positives = 76/203 (37%), Gaps = 50/203 (24%)

Query: 110 GSRKPDQPYEWL---------SYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEW 160
           G R P+  + W+         S++++ +L+  + +   Q       D  + +     PEW
Sbjct: 66  GKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDH-LALMLPRVPEW 124

Query: 161 VIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPG 220
            ++  GC    ++ +P    L  + I Y   + +LS                        
Sbjct: 125 WLVAVGCMRTGIIFIPATILLKAKDILY---RLQLSKA---------------------- 159

Query: 221 LKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRAN----RRKPKPPAPE-------- 268
            K IV +DA  SE+     +C    T +  + D  R      R   K  +PE        
Sbjct: 160 -KGIVTIDALASEVDSIASQCPSLKTKL-LVSDHSREGWLDFRSLVKSASPEHTCVKSKT 217

Query: 269 -DLAVICFTSGTTGNPKGAMVTH 290
            D  VI FTSGTTG PK A  +H
Sbjct: 218 LDPMVIFFTSGTTGFPKMAKHSH 240


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
           sapiens]
          Length = 480

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 2/105 (1%)

Query: 408 NNSLWDRLIFHKVQSSLGGR-VRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAG 466
           N  ++  L+ HK  +S   + ++  V    P+S  V+   +       YEGYGQTE    
Sbjct: 317 NPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLL 376

Query: 467 CCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVK 511
           C  +         +G P+P  ++++VD E  N +    EG + ++
Sbjct: 377 CATSKTIKLKPSSLGKPLPPYIVQIVD-ENSNLLPPGEEGNIAIR 420


>gi|13325057 solute carrier family 27 (fatty acid transporter),
           member 5 [Homo sapiens]
          Length = 690

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 14/86 (16%)

Query: 254 LGRANRRKPKPPAPEDL---------AVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKAT 304
           LG A    P  P P DL         A+  +TSGTTG PK A++TH  ++   S  +  +
Sbjct: 264 LGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVL-QMSKMLSLS 322

Query: 305 ENTVNPCPDDTLISFLPLAHMFERVV 330
             T     DD + + LPL H+   VV
Sbjct: 323 GATA----DDVVYTVLPLYHVMGLVV 344


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 5/62 (8%)

Query: 264 PPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLA 323
           P +  D  +  FTSGTTG PK A ++H  I+  C  F +          +D +   LPL 
Sbjct: 323 PQSITDTCLYIFTSGTTGLPKAARISHLKIL-QCQGFYQ----LCGVHQEDVIYLALPLY 377

Query: 324 HM 325
           HM
Sbjct: 378 HM 379


>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
          Length = 1098

 Score = 34.3 bits (77), Expect = 0.40
 Identities = 53/242 (21%), Positives = 88/242 (36%), Gaps = 26/242 (10%)

Query: 150 IGIFAQ---NRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKA 206
           IG++ Q   + P W++   G        VP+         T+ + K  L  + V+K +  
Sbjct: 61  IGLYCQPGIDLPSWIL---GILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQIN 117

Query: 207 KL-----LLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRK 261
           K       L   +   +    +++    + +  V      G E    + ++ +   +  +
Sbjct: 118 KFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNE 177

Query: 262 PKPPAPEDL------AVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDT 315
            K     DL      A +  TSGTTG PK   V H+ IV +   F    + T     +D 
Sbjct: 178 EKAEEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDIT----QEDV 233

Query: 316 LISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVL-----QPTVFPVVPRLL 370
           L    PL      V   + L  GA +      ++LL   L  +     + TV    P LL
Sbjct: 234 LFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLL 293

Query: 371 NR 372
            R
Sbjct: 294 RR 295


>gi|40807357 solute carrier family 27 (fatty acid transporter),
           member 4 [Homo sapiens]
          Length = 643

 Score = 34.3 bits (77), Expect = 0.40
 Identities = 54/228 (23%), Positives = 88/228 (38%), Gaps = 30/228 (13%)

Query: 122 SYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTL 181
           +++Q+ E S  + + L  +G   A      IF +NR E+V +  G     +    +   L
Sbjct: 103 TFRQLDEYSSSVANFLQARGL--ASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNL 160

Query: 182 GNEAITYIVNKAEL-SLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240
             +A+ + +  +   +LVF    E A  + E V   L P L +                 
Sbjct: 161 RRDALLHCLTTSRARALVFGS--EMASAICE-VHASLDPSLSLFC----------SGSWE 207

Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPE----DLAVICFTSGTTGNPKGAMVTHRNIVSD 296
            G    S + ++ L + +  K  P  P+    D     +TSGTTG PK A+V H      
Sbjct: 208 PGAVPPSTEHLDPLLK-DAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRM 266

Query: 297 CSAFVKATENTVNPCPDDTLISFLPLAHMFERVV---ECVMLCHGAKI 341
            +             P+D +   LPL H    +V   +C  L HG  +
Sbjct: 267 AALVYYGFRMR----PNDIVYDCLPLYHSAGNIVGIGQC--LLHGMTV 308


>gi|227499619 solute carrier family 27 (fatty acid transporter),
           member 2 isoform 1 [Homo sapiens]
          Length = 620

 Score = 33.9 bits (76), Expect = 0.52
 Identities = 14/23 (60%), Positives = 18/23 (78%)

Query: 271 AVICFTSGTTGNPKGAMVTHRNI 293
           A+  +TSGTTG PK AM+TH+ I
Sbjct: 220 ALYIYTSGTTGLPKAAMITHQRI 242


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,037,550
Number of Sequences: 37866
Number of extensions: 1232583
Number of successful extensions: 2555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2447
Number of HSP's gapped (non-prelim): 63
length of query: 698
length of database: 18,247,518
effective HSP length: 109
effective length of query: 589
effective length of database: 14,120,124
effective search space: 8316753036
effective search space used: 8316753036
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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