BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo sapiens] (698 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo... 1419 0.0 gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo... 1004 0.0 gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo... 994 0.0 gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 876 0.0 gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 876 0.0 gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 876 0.0 gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo... 323 3e-88 gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo... 323 3e-88 gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor... 310 2e-84 gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo... 310 2e-84 gi|27477105 lipidosin [Homo sapiens] 181 3e-45 gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens] 155 1e-37 gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 82 2e-15 gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 82 2e-15 gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 79 1e-14 gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 60 5e-09 gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 60 7e-09 gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 60 7e-09 gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 60 9e-09 gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 58 3e-08 gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 48 4e-05 gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 47 6e-05 gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 47 6e-05 gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 46 1e-04 gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 44 5e-04 gi|13325057 solute carrier family 27 (fatty acid transporter), m... 42 0.002 gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 36 0.11 gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens] 34 0.40 gi|40807357 solute carrier family 27 (fatty acid transporter), m... 34 0.40 gi|227499619 solute carrier family 27 (fatty acid transporter), ... 34 0.52 >gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo sapiens] Length = 698 Score = 1419 bits (3673), Expect = 0.0 Identities = 698/698 (100%), Positives = 698/698 (100%) Query: 1 MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60 MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ Sbjct: 1 MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60 Query: 61 SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120 SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW Sbjct: 61 SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120 Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT Sbjct: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180 Query: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR Sbjct: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240 Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF Sbjct: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300 Query: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP Sbjct: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360 Query: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV Sbjct: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420 Query: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV Sbjct: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480 Query: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD Sbjct: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540 Query: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI Sbjct: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600 Query: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP Sbjct: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660 Query: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV 698 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV Sbjct: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV 698 >gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform b [Homo sapiens] Length = 722 Score = 1004 bits (2596), Expect = 0.0 Identities = 466/694 (67%), Positives = 570/694 (82%) Query: 1 MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60 MQ E+ R R+PEL D Q+ R+L TL+ GA AA+ +W+ RPK L+PPC+L MQ Sbjct: 26 MQTQEILRILRLPELGDLGQFFRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQ 85 Query: 61 SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120 S EV SGGARRS + + L ++YDD T+Y+ F+RG+ +S NGPCLG RKP QPY+W Sbjct: 86 SEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQW 145 Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180 LSY++VA+ +E +GS L+Q K DQFIG+FAQNRPEW+I+E C+ YSMV+VPLYDT Sbjct: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205 Query: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240 LG AI YI+N A++S V VDKP+KA LLLE VE K PGLK+I++MD + L ERGQ+ Sbjct: 206 LGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQK 265 Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300 CGV + SM+A+ED G+ N + P PP P+DL+++CFTSGTTGNPKGAM+TH N+V+D S F Sbjct: 266 CGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGF 325 Query: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360 +K TE + P DD LISFLPLAHMFERV++ V+ CHG ++GFFQGDIRLL DD+K L P Sbjct: 326 LKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCP 385 Query: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420 T+FPVVPRLLNRM+D+IF QANT LKRWLL+FA+KRK+AE+RSGIIRN+S+WD L F+K+ Sbjct: 386 TIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKI 445 Query: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480 Q+SLGG VR++VTGAAP S TVL FLRAALGCQ YEGYGQTECTAGC T PGDWT+GHV Sbjct: 446 QASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHV 505 Query: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540 GAP+PCN IKLVDVEE+NY A +GEGE+CV+GPNVF+GYLKDP +T EALD DGWLHTGD Sbjct: 506 GAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGD 565 Query: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600 IGKWLP GTLKIIDRKKHIFKLAQGEY+APEKIENIY+RS+PVAQ++VHG+SL+AFL+ I Sbjct: 566 IGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGI 625 Query: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660 VVPD E + SWAQKRG EG++ +LC NKD+KKAILEDMVRLGK+SGL FEQVK I +H Sbjct: 626 VVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHS 685 Query: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYS 694 ++FS+ NGLLTPT+KAKRPELR YF+ QI++LYS Sbjct: 686 DMFSVQNGLLTPTLKAKRPELREYFKKQIEELYS 719 >gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform a [Homo sapiens] Length = 722 Score = 994 bits (2571), Expect = 0.0 Identities = 463/694 (66%), Positives = 568/694 (81%) Query: 1 MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ 60 MQ E+ R R+PEL D Q+ R+L TL+ GA AA+ +W+ RPK L+PPC+L MQ Sbjct: 26 MQTQEILRILRLPELGDLGQFFRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQ 85 Query: 61 SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW 120 S EV SGGARRS + + L ++YDD T+Y+ F+RG+ +S NGPCLG RKP QPY+W Sbjct: 86 SEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQW 145 Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180 LSY++VA+ +E +GS L+Q K DQFIG+FAQNRPEW+I+E C+ YSMV+VPLYDT Sbjct: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205 Query: 181 LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240 LG AI YI+N A++S V VDKP+KA LLLE VE K PGLK+I++MD + L ERGQ+ Sbjct: 206 LGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQK 265 Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF 300 CGV + SM+A+ED G+ N + P PP P+DL+++CFTSGTTGNPKGAM+TH N+V+D S F Sbjct: 266 CGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGF 325 Query: 301 VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP 360 +K TE+ P D IS+LPLAHMFER+V+ V+ CHG ++GFFQGDIRLL DD+K L P Sbjct: 326 LKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCP 385 Query: 361 TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV 420 T+FPVVPRLLNRM+D+IF QANT LKRWLL+FA+KRK+AE+RSGIIRN+S+WD L F+K+ Sbjct: 386 TIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKI 445 Query: 421 QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV 480 Q+SLGG VR++VTGAAP S TVL FLRAALGCQ YEGYGQTECTAGC T PGDWT+GHV Sbjct: 446 QASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHV 505 Query: 481 GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540 GAP+PCN IKLVDVEE+NY A +GEGE+CV+GPNVF+GYLKDP +T EALD DGWLHTGD Sbjct: 506 GAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGD 565 Query: 541 IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI 600 IGKWLP GTLKIIDRKKHIFKLAQGEY+APEKIENIY+RS+PVAQ++VHG+SL+AFL+ I Sbjct: 566 IGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGI 625 Query: 601 VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP 660 VVPD E + SWAQKRG EG++ +LC NKD+KKAILEDMVRLGK+SGL FEQVK I +H Sbjct: 626 VVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHS 685 Query: 661 ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYS 694 ++FS+ NGLLTPT+KAKRPELR YF+ QI++LYS Sbjct: 686 DMFSVQNGLLTPTLKAKRPELREYFKKQIEELYS 719 >gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform b [Homo sapiens] Length = 683 Score = 876 bits (2263), Expect = 0.0 Identities = 414/673 (61%), Positives = 527/673 (78%), Gaps = 2/673 (0%) Query: 25 LPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVY 84 LPT L+ F A W TRP+P+ P DL+ QSV + GGAR+ +++ Sbjct: 12 LPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGI--EGGARKGVSQKNNDLTSC 69 Query: 85 FYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKT 144 + D T+YE FQRG+ VS+NGPCLG RKP+QPY WLSYKQV++ +E +GS L+ KG+K+ Sbjct: 70 CFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKS 129 Query: 145 APDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPE 204 +PDQF+GIFAQNRPEW+I E C+ YSMV VPLYDTLG EAI +IVNKA++++V D P+ Sbjct: 130 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 189 Query: 205 KAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKP 264 KA +L+ VE P LK+I++MD + +L +RG++ G+E+ S+ E+LG+ + RKP P Sbjct: 190 KALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVP 249 Query: 265 PAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAH 324 P+PEDL+VICFTSGTTG+PKGAM+TH+NIVS+ +AF+K E+ P PDD IS+LPLAH Sbjct: 250 PSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309 Query: 325 MFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTT 384 MFER+V+ V+ GA++GFFQGDIRLL DD+K L+PT+FP VPRLLNR++D++ +A T Sbjct: 310 MFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP 369 Query: 385 LKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLT 444 LK++LL A K EL+ GIIR++S WD+LIF K+Q SLGGRVR++VTGAAP+S +V+T Sbjct: 370 LKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMT 429 Query: 445 FLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG 504 F RAA+GCQ YE YGQTECT GC T+PGDWT+GHVG P+ CN +KL DV +MNY Sbjct: 430 FFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN 489 Query: 505 EGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQ 564 EGEVC+KG NVF+GYLKDP KT EALD DGWLHTGDIG+WLPNGTLKIIDRKK+IFKLAQ Sbjct: 490 EGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQ 549 Query: 565 GEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL 624 GEYIAPEKIENIY RS+PV Q+FVHGESL++ L+ +VVPD + L S+A K G +GSFEEL Sbjct: 550 GEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEEL 609 Query: 625 CRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNY 684 C+N+ V++AILED+ ++GK+SGLK FEQVK I LHPE FSI+NGLLTPT+KAKR EL Y Sbjct: 610 CQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKY 669 Query: 685 FRSQIDDLYSTIK 697 FR+QID LY I+ Sbjct: 670 FRTQIDSLYEHIQ 682 >gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform b [Homo sapiens] Length = 683 Score = 876 bits (2263), Expect = 0.0 Identities = 414/673 (61%), Positives = 527/673 (78%), Gaps = 2/673 (0%) Query: 25 LPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVY 84 LPT L+ F A W TRP+P+ P DL+ QSV + GGAR+ +++ Sbjct: 12 LPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGI--EGGARKGVSQKNNDLTSC 69 Query: 85 FYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKT 144 + D T+YE FQRG+ VS+NGPCLG RKP+QPY WLSYKQV++ +E +GS L+ KG+K+ Sbjct: 70 CFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKS 129 Query: 145 APDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPE 204 +PDQF+GIFAQNRPEW+I E C+ YSMV VPLYDTLG EAI +IVNKA++++V D P+ Sbjct: 130 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 189 Query: 205 KAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKP 264 KA +L+ VE P LK+I++MD + +L +RG++ G+E+ S+ E+LG+ + RKP P Sbjct: 190 KALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVP 249 Query: 265 PAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAH 324 P+PEDL+VICFTSGTTG+PKGAM+TH+NIVS+ +AF+K E+ P PDD IS+LPLAH Sbjct: 250 PSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309 Query: 325 MFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTT 384 MFER+V+ V+ GA++GFFQGDIRLL DD+K L+PT+FP VPRLLNR++D++ +A T Sbjct: 310 MFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP 369 Query: 385 LKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLT 444 LK++LL A K EL+ GIIR++S WD+LIF K+Q SLGGRVR++VTGAAP+S +V+T Sbjct: 370 LKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMT 429 Query: 445 FLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG 504 F RAA+GCQ YE YGQTECT GC T+PGDWT+GHVG P+ CN +KL DV +MNY Sbjct: 430 FFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN 489 Query: 505 EGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQ 564 EGEVC+KG NVF+GYLKDP KT EALD DGWLHTGDIG+WLPNGTLKIIDRKK+IFKLAQ Sbjct: 490 EGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQ 549 Query: 565 GEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL 624 GEYIAPEKIENIY RS+PV Q+FVHGESL++ L+ +VVPD + L S+A K G +GSFEEL Sbjct: 550 GEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEEL 609 Query: 625 CRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNY 684 C+N+ V++AILED+ ++GK+SGLK FEQVK I LHPE FSI+NGLLTPT+KAKR EL Y Sbjct: 610 CQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKY 669 Query: 685 FRSQIDDLYSTIK 697 FR+QID LY I+ Sbjct: 670 FRTQIDSLYEHIQ 682 >gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform a [Homo sapiens] Length = 739 Score = 876 bits (2263), Expect = 0.0 Identities = 414/673 (61%), Positives = 527/673 (78%), Gaps = 2/673 (0%) Query: 25 LPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVY 84 LPT L+ F A W TRP+P+ P DL+ QSV + GGAR+ +++ Sbjct: 68 LPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGI--EGGARKGVSQKNNDLTSC 125 Query: 85 FYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKT 144 + D T+YE FQRG+ VS+NGPCLG RKP+QPY WLSYKQV++ +E +GS L+ KG+K+ Sbjct: 126 CFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKS 185 Query: 145 APDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPE 204 +PDQF+GIFAQNRPEW+I E C+ YSMV VPLYDTLG EAI +IVNKA++++V D P+ Sbjct: 186 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 245 Query: 205 KAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKP 264 KA +L+ VE P LK+I++MD + +L +RG++ G+E+ S+ E+LG+ + RKP P Sbjct: 246 KALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVP 305 Query: 265 PAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAH 324 P+PEDL+VICFTSGTTG+PKGAM+TH+NIVS+ +AF+K E+ P PDD IS+LPLAH Sbjct: 306 PSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 365 Query: 325 MFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTT 384 MFER+V+ V+ GA++GFFQGDIRLL DD+K L+PT+FP VPRLLNR++D++ +A T Sbjct: 366 MFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTP 425 Query: 385 LKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLT 444 LK++LL A K EL+ GIIR++S WD+LIF K+Q SLGGRVR++VTGAAP+S +V+T Sbjct: 426 LKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMT 485 Query: 445 FLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG 504 F RAA+GCQ YE YGQTECT GC T+PGDWT+GHVG P+ CN +KL DV +MNY Sbjct: 486 FFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN 545 Query: 505 EGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQ 564 EGEVC+KG NVF+GYLKDP KT EALD DGWLHTGDIG+WLPNGTLKIIDRKK+IFKLAQ Sbjct: 546 EGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQ 605 Query: 565 GEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL 624 GEYIAPEKIENIY RS+PV Q+FVHGESL++ L+ +VVPD + L S+A K G +GSFEEL Sbjct: 606 GEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEEL 665 Query: 625 CRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNY 684 C+N+ V++AILED+ ++GK+SGLK FEQVK I LHPE FSI+NGLLTPT+KAKR EL Y Sbjct: 666 CQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKY 725 Query: 685 FRSQIDDLYSTIK 697 FR+QID LY I+ Sbjct: 726 FRTQIDSLYEHIQ 738 >gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo sapiens] Length = 720 Score = 323 bits (828), Expect = 3e-88 Identities = 205/599 (34%), Positives = 321/599 (53%), Gaps = 36/599 (6%) Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177 Y WLSY+ V + G+ L G K P I IF + R EW+I Q CF Y+ +V L Sbjct: 132 YNWLSYEDVFVRAFNFGNGLQMLGQK--PKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189 Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVER 237 Y TLG AI + +N+ E++ + K E + L+ + + L+P L+ I+ +D E Sbjct: 190 YATLGGPAIVHALNETEVTNIITSK-ELLQTKLKDIVS-LVPRLRHIITVDGKPPTWSEF 247 Query: 238 GQRCGVEVTSMKAMEDLGRANRRKPKP---PAPEDLAVICFTSGTTGNPKGAMVTHRNIV 294 + G+ V +M A+E LG + +P P P D+AVI +TSG+TG PKG M++H NI+ Sbjct: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305 Query: 295 SDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMD- 353 + + E +D I +LPLAH+ E E V L HG +IG+ + L D Sbjct: 306 AGITGMA---ERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360 Query: 354 ----------DLKVLQPTVFPVVPRLLNRMFDRIFGQAN--TTLKRWLLDFASKRKEAEL 401 D +L+PT+ VP +++R++ + + + ++ +R L A K ++ Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420 Query: 402 RSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQT 461 G RN L D +F KV+S LGG +RL++ G AP+SAT F+ C +GYG T Sbjct: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478 Query: 462 ECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKGPNVFQG 518 E ++ D+ G VGAP+ C IKL + EE Y + GE+ + G +V G Sbjct: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538 Query: 519 YLKDPAKTAEAL--DKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIE 574 Y K+ AKT D++G WL TGDIG++ P+G LKIIDRKK + KL GEY++ K+E Sbjct: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598 Query: 575 NIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAI 634 V + + S +++I VVP+ + L A+K+G +G++EELC + +++ + Sbjct: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658 Query: 635 LEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLY 693 L+ + + L+ FE I L PE ++ + GL+T K KR EL+ ++++ I+ +Y Sbjct: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717 >gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo sapiens] Length = 720 Score = 323 bits (828), Expect = 3e-88 Identities = 205/599 (34%), Positives = 321/599 (53%), Gaps = 36/599 (6%) Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177 Y WLSY+ V + G+ L G K P I IF + R EW+I Q CF Y+ +V L Sbjct: 132 YNWLSYEDVFVRAFNFGNGLQMLGQK--PKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189 Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVER 237 Y TLG AI + +N+ E++ + K E + L+ + + L+P L+ I+ +D E Sbjct: 190 YATLGGPAIVHALNETEVTNIITSK-ELLQTKLKDIVS-LVPRLRHIITVDGKPPTWSEF 247 Query: 238 GQRCGVEVTSMKAMEDLGRANRRKPKP---PAPEDLAVICFTSGTTGNPKGAMVTHRNIV 294 + G+ V +M A+E LG + +P P P D+AVI +TSG+TG PKG M++H NI+ Sbjct: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305 Query: 295 SDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMD- 353 + + E +D I +LPLAH+ E E V L HG +IG+ + L D Sbjct: 306 AGITGMA---ERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360 Query: 354 ----------DLKVLQPTVFPVVPRLLNRMFDRIFGQAN--TTLKRWLLDFASKRKEAEL 401 D +L+PT+ VP +++R++ + + + ++ +R L A K ++ Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420 Query: 402 RSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQT 461 G RN L D +F KV+S LGG +RL++ G AP+SAT F+ C +GYG T Sbjct: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478 Query: 462 ECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKGPNVFQG 518 E ++ D+ G VGAP+ C IKL + EE Y + GE+ + G +V G Sbjct: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538 Query: 519 YLKDPAKTAEAL--DKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIE 574 Y K+ AKT D++G WL TGDIG++ P+G LKIIDRKK + KL GEY++ K+E Sbjct: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598 Query: 575 NIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAI 634 V + + S +++I VVP+ + L A+K+G +G++EELC + +++ + Sbjct: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658 Query: 635 LEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLY 693 L+ + + L+ FE I L PE ++ + GL+T K KR EL+ ++++ I+ +Y Sbjct: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717 >gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1 [Homo sapiens] Length = 670 Score = 310 bits (795), Expect = 2e-84 Identities = 199/605 (32%), Positives = 316/605 (52%), Gaps = 48/605 (7%) Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177 Y+W++Y +V GS L G K P I IF + R EW+I Q CF Y+ +V L Sbjct: 82 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 139 Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKL------IPGLKIIVVMDAYG 231 Y TLG EA+ + +N++E S + +E +E+KL I +K I+ +D Sbjct: 140 YATLGKEAVVHGLNESEASYLITS--------VELLESKLKTALLDISCVKHIIYVDNKA 191 Query: 232 SELVERGQRCGVEVTSMKAMEDLGRANRR---KPKPPAPEDLAVICFTSGTTGNPKGAMV 288 E + G E+ SM+++E+LG P P P D+A++ +TSG+TG PKG M+ Sbjct: 192 INKAEYPE--GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 249 Query: 289 THRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDI 348 H N+++ + E P DT I +LPLAH+ E E +G +IG+ Sbjct: 250 HHSNLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 304 Query: 349 RLLMD-----------DLKVLQPTVFPVVPRLLNRMFDRIFG--QANTTLKRWLLDFASK 395 L D D VL+PT+ VP +++R++ + Q +++ L Sbjct: 305 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 364 Query: 396 RKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFY 455 K +++ G + L + L+F KV++ LGG VR+M++G AP+S F+ C Sbjct: 365 YKLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIG 422 Query: 456 EGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKG 512 +GYG TE +T D+T G VGAP+ C IKL D +E Y + GE+ + G Sbjct: 423 QGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGG 482 Query: 513 PNVFQGYLKDPAKTAE--ALDKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYI 568 N+ GY K+ KTAE ++D++G W TGDIG++ P+G L+IIDRKK + KL GEY+ Sbjct: 483 QNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYV 542 Query: 569 APEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNK 628 + K+E + + +S Q+++I+ VVP+ + L AQ++G EG++ ++C N Sbjct: 543 SLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNP 602 Query: 629 DVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQ 688 ++ IL+++ L+ FE + L PE ++ + GL+T K KR ELRN++ Sbjct: 603 AMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKD 662 Query: 689 IDDLY 693 I+ +Y Sbjct: 663 IERMY 667 >gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform 2 [Homo sapiens] Length = 711 Score = 310 bits (795), Expect = 2e-84 Identities = 199/605 (32%), Positives = 316/605 (52%), Gaps = 48/605 (7%) Query: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177 Y+W++Y +V GS L G K P I IF + R EW+I Q CF Y+ +V L Sbjct: 123 YKWMNYLEVNRRVNNFGSGLTALGLK--PKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180 Query: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKL------IPGLKIIVVMDAYG 231 Y TLG EA+ + +N++E S + +E +E+KL I +K I+ +D Sbjct: 181 YATLGKEAVVHGLNESEASYLITS--------VELLESKLKTALLDISCVKHIIYVDNKA 232 Query: 232 SELVERGQRCGVEVTSMKAMEDLGRANRR---KPKPPAPEDLAVICFTSGTTGNPKGAMV 288 E + G E+ SM+++E+LG P P P D+A++ +TSG+TG PKG M+ Sbjct: 233 INKAEYPE--GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 290 Query: 289 THRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDI 348 H N+++ + E P DT I +LPLAH+ E E +G +IG+ Sbjct: 291 HHSNLIAGMTG---QCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY--SSP 345 Query: 349 RLLMD-----------DLKVLQPTVFPVVPRLLNRMFDRIFG--QANTTLKRWLLDFASK 395 L D D VL+PT+ VP +++R++ + Q +++ L Sbjct: 346 LTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYD 405 Query: 396 RKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFY 455 K +++ G + L + L+F KV++ LGG VR+M++G AP+S F+ C Sbjct: 406 YKLEQIKKGY--DAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIG 463 Query: 456 EGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKG 512 +GYG TE +T D+T G VGAP+ C IKL D +E Y + GE+ + G Sbjct: 464 QGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGG 523 Query: 513 PNVFQGYLKDPAKTAE--ALDKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYI 568 N+ GY K+ KTAE ++D++G W TGDIG++ P+G L+IIDRKK + KL GEY+ Sbjct: 524 QNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYV 583 Query: 569 APEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNK 628 + K+E + + +S Q+++I+ VVP+ + L AQ++G EG++ ++C N Sbjct: 584 SLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNP 643 Query: 629 DVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQ 688 ++ IL+++ L+ FE + L PE ++ + GL+T K KR ELRN++ Sbjct: 644 AMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKD 703 Query: 689 IDDLY 693 I+ +Y Sbjct: 704 IERMY 708 >gi|27477105 lipidosin [Homo sapiens] Length = 724 Score = 181 bits (458), Expect = 3e-45 Identities = 173/641 (26%), Positives = 287/641 (44%), Gaps = 53/641 (8%) Query: 91 TLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKTAPDQFI 150 T++ F + + LG ++ D+ +E +SY Q L+ ++ G K A + Sbjct: 104 TVHRMFYEALDKYGDLIALGFKRQDK-WEHISYSQYYLLARRAAKGFLKLGLKQAHS--V 160 Query: 151 GIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLL 210 I N PEW G ++ +Y T EA YI +++ VD ++ + +L Sbjct: 161 AILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKIL 220 Query: 211 EGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKP-----KPP 265 + K +P LK +V+ E V +M+ +LG + Sbjct: 221 KIW--KQLPHLKAVVIYK-------EPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQ 271 Query: 266 APEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHM 325 P V+ +TSGTTGNPKG M++ NI +A + + ++S+LPL+H+ Sbjct: 272 QPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHI 331 Query: 326 FERVVEC-VMLCHGAKIGFFQGDIRL--LMDDLKVLQPTVFPVVPRLLNRMFDRI---FG 379 ++ + + GA++ F + D L++ L+ ++PT VPR+ ++ +RI Sbjct: 332 AAQIYDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAA 391 Query: 380 QANTTLKRWLLDFASKRKEAELR--SGIIR--NNSLWDRLIFHKVQSSLG-GRVRLMVTG 434 Q+ ++ LL S E L ++ L D L+ KV+ +LG + + G Sbjct: 392 QSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYG 451 Query: 435 AAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDV 494 AAP+ A F L + Y GYG +E + ++ P ++ G +P +KLV+ Sbjct: 452 AAPMMAETQHFF-LGLNIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQ 510 Query: 495 EEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIID 554 + AEG GE+C+ G +F GYL KT EA+D++GWLHTGD G+ +G L I Sbjct: 511 D------AEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITG 564 Query: 555 RKKHIFKLAQGEYIAPEKIEN-IYMRSEPVAQVFVHGE-----SLQAFLIAIVVPD---- 604 R K + A GE + P IE + M ++ + G+ S+ L + PD Sbjct: 565 RLKELIITAGGENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQ 624 Query: 605 ----VETLCSWAQKRGFEG-SFEELCRNKD--VKKAILEDMVRLGKDSGLKPFEQVKGIT 657 E + Q+ G + E+ KD V +AI E + R+ ++ +P+ K Sbjct: 625 TDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAI 684 Query: 658 LHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV 698 L + FSI G L PTMK KR + ++ ID Y K+ Sbjct: 685 LERD-FSISGGELGPTMKLKRLTVLEKYKGIIDSFYQEQKM 724 >gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens] Length = 666 Score = 155 bits (392), Expect = 1e-37 Identities = 157/641 (24%), Positives = 293/641 (45%), Gaps = 65/641 (10%) Query: 91 TLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKTAPDQFI 150 T+ E F+ + P L S K + +E L++ Q E +LI+ G + + Sbjct: 52 TIPEFFRESVNRFGTYPALAS-KNGKKWEILNFNQYYEACRKAAKSLIKLGLERFHG--V 108 Query: 151 GIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLL 210 GI N EW I G + V +Y T E Y++ A+++++ V+ ++ + +L Sbjct: 109 GILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVENDQQLQKIL 168 Query: 211 EGVENKLIPGLKIIVVM--------DAYG-SELVERGQRCGVEVTSMKAMEDLGRANRRK 261 ++ L P LK I+ + Y + +E G+ + T ++ + + +AN+ Sbjct: 169 SIPQSSLEP-LKAIIQYRLPMKKNNNLYSWDDFMELGR--SIPDTQLEQVIESQKANQ-- 223 Query: 262 PKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLP 321 AV+ +TSGTTG PKG M++H NI A K + T +T++S+LP Sbjct: 224 --------CAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKLTDK---HETVVSYLP 272 Query: 322 LAHMFERVVEC-VMLCHGAKIGFFQGDIR--LLMDDLKVLQPTVFPVVPRLLNRMFDRIF 378 L+H+ ++++ V + GA F Q D L+ LK ++PTVF VP++ ++ + + Sbjct: 273 LSHIAAQMMDIWVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVK 332 Query: 379 GQANTT--LKR----WLLDFASKRKEAEL--RSGIIRNNSLWDRLIFHKVQSSLG-GRVR 429 + + LK+ W + K ++ + + + L+F KV++SLG Sbjct: 333 KNSAKSMGLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCH 392 Query: 430 LMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLI 489 ++G AP++ F +L E YG +E + ++ ++ + C I Sbjct: 393 SFISGTAPLNQETAEFF-LSLDIPIGELYGLSESSGPHTISNQNNYRL------LSCGKI 445 Query: 490 KLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGT 549 + +G GE+C+ G ++F GYL+ +T EA+D +GWLH+GD+G+ G Sbjct: 446 LTGCKNMLFQQNKDGIGEICLWGRHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLGF 505 Query: 550 LKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEP-VAQVFVHGESLQ--AFLIAIVVPDVE 606 L + K I A GE + P +E + + P ++ + G+ L+ + L+ + + Sbjct: 506 LYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISNAMLVGDKLKFLSMLLTLKCEMNQ 565 Query: 607 TLCSWAQKRGFE------------GSFEELCRNKD--VKKAILEDMVRLGKDSGLKPFEQ 652 K FE + E+ + +D V KAI + + + +++ + ++ Sbjct: 566 MSGEPLDKLNFEAINFCRGLGSQASTVTEIVKQQDPLVYKAIQQGINAVNQEA-MNNAQR 624 Query: 653 VKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLY 693 ++ + + FSI G L P MK KR + ++ QID +Y Sbjct: 625 IEKWVILEKDFSIYGGELGPMMKLKRHFVAQKYKKQIDHMY 665 >gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] Length = 576 Score = 81.6 bits (200), Expect = 2e-15 Identities = 110/452 (24%), Positives = 178/452 (39%), Gaps = 109/452 (24%) Query: 124 KQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGN 183 +++ L C+G L ++ + N +V+ + + V VPLY Sbjct: 80 QEICRLCGCVGGDL--------REERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA 131 Query: 184 EAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGV 243 + Y++ ++ S+V ++ LL V KL G+ ++ + A + VE V Sbjct: 132 AQLEYVICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLLPLTPAIYTGAVEEPAEVPV 187 Query: 244 EVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKA 303 + G N+ A+I +TSGTTG PKG + TH+NI + + V Sbjct: 188 P--------EQGWRNKG----------AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHK 229 Query: 304 TENTVNPCPDDTLISFLPLAHMFERV----------VECVMLCHGAKIGFFQGDIRLLMD 353 T DD ++ LPL H+ V CVM+ + ++ + L Sbjct: 230 WAWT----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWE---KFLSS 282 Query: 354 DLKVLQPTVFPVVPRLLNRM---FDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNS 410 + + VF VP + ++ +DR F Q + DF Sbjct: 283 ETPRIN--VFMAVPTIYTKLMEYYDRHFTQPHAQ------DF------------------ 316 Query: 411 LWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLT 470 +++ ++RLMV+G+A + VL + G E YG TE G L+ Sbjct: 317 ---------LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI--GMALS 365 Query: 471 MPGDWTA---GHVGAPMPCNLIKLVDV----EEMNY-MAAEG--------------EGEV 508 P G VG P+P +++V E +Y + AEG EGE+ Sbjct: 366 GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGEL 425 Query: 509 CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540 V+GP+VF+ Y P +T A DGW TGD Sbjct: 426 LVRGPSVFREYWNKPEETKSAFTLDGWFKTGD 457 >gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] Length = 576 Score = 81.6 bits (200), Expect = 2e-15 Identities = 110/452 (24%), Positives = 178/452 (39%), Gaps = 109/452 (24%) Query: 124 KQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGN 183 +++ L C+G L ++ + N +V+ + + V VPLY Sbjct: 80 QEICRLCGCVGGDL--------REERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA 131 Query: 184 EAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGV 243 + Y++ ++ S+V ++ LL V KL G+ ++ + A + VE V Sbjct: 132 AQLEYVICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLLPLTPAIYTGAVEEPAEVPV 187 Query: 244 EVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKA 303 + G N+ A+I +TSGTTG PKG + TH+NI + + V Sbjct: 188 P--------EQGWRNKG----------AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHK 229 Query: 304 TENTVNPCPDDTLISFLPLAHMFERV----------VECVMLCHGAKIGFFQGDIRLLMD 353 T DD ++ LPL H+ V CVM+ + ++ + L Sbjct: 230 WAWT----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWE---KFLSS 282 Query: 354 DLKVLQPTVFPVVPRLLNRM---FDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNS 410 + + VF VP + ++ +DR F Q + DF Sbjct: 283 ETPRIN--VFMAVPTIYTKLMEYYDRHFTQPHAQ------DF------------------ 316 Query: 411 LWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLT 470 +++ ++RLMV+G+A + VL + G E YG TE G L+ Sbjct: 317 ---------LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI--GMALS 365 Query: 471 MPGDWTA---GHVGAPMPCNLIKLVDV----EEMNY-MAAEG--------------EGEV 508 P G VG P+P +++V E +Y + AEG EGE+ Sbjct: 366 GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGEL 425 Query: 509 CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540 V+GP+VF+ Y P +T A DGW TGD Sbjct: 426 LVRGPSVFREYWNKPEETKSAFTLDGWFKTGD 457 >gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] Length = 615 Score = 79.3 bits (194), Expect = 1e-14 Identities = 108/491 (21%), Positives = 190/491 (38%), Gaps = 69/491 (14%) Query: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180 L++ Q+ E + S L+ G +G++ N WV+++ +++V + Sbjct: 100 LTFAQLKEEVDKAASGLLSIGL--CKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157 Query: 181 LGNEAITYIVNKAELSLVFVDKPEKA-------KLLLEGVEN--------KLIPGLKIIV 225 + Y++ K + K K K + VEN + +P L ++ Sbjct: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217 Query: 226 VMDAY--GSELVERGQRCGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNP 283 +DA G+ L++ G S + D + N++ P ++ FTSGTTG+P Sbjct: 218 SVDAPLPGTLLLDEVVAAG----STRQHLDQLQYNQQFLSCHDPINIQ---FTSGTTGSP 270 Query: 284 KGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVM-LCHGAKIG 342 KGA ++H NIV++ + + + +I PL H V +M L +GA + Sbjct: 271 KGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATL- 329 Query: 343 FFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELR 402 +L +F + + I + T L F + + Sbjct: 330 --------------ILASPIFNG-----KKALEAISRERGTFLYGTPTMFVDILNQPDFS 370 Query: 403 SGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTE 462 S + + + GG ++ G+ + + YG TE Sbjct: 371 S--------------YDISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTE 412 Query: 463 CTAGCCLTMPGDWT---AGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGY 519 + P D A VG MP +++++E GE+C++G V GY Sbjct: 413 NSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGY 472 Query: 520 LKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMR 579 +P KT EA+D+D W TGD+ G KI+ R K + + GE I P ++E+ + Sbjct: 473 WGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMI-IRGGENIYPAELEDFFHT 531 Query: 580 SEPVAQVFVHG 590 V +V V G Sbjct: 532 HPKVQEVQVVG 542 >gi|42544132 SA hypertension-associated homolog isoform 1 [Homo sapiens] Length = 586 Score = 60.5 bits (145), Expect = 5e-09 Identities = 53/179 (29%), Positives = 81/179 (45%), Gaps = 15/179 (8%) Query: 432 VTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKL 491 V+ P++ V R G YEGYGQTE C G +G P P +K+ Sbjct: 350 VSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKI 409 Query: 492 VDVEEMNYMAAEGEGEVCVKG-PN----VFQGYLKDPAKTAEALDKDGWLHTGDIGKWLP 546 VDV N + EG++ ++ PN +F Y+ +P+KTA L + + TGD G Sbjct: 410 VDVNG-NVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTL-RGNFYITGDRGYMDK 467 Query: 547 NGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFV-------HGESLQAFLI 598 +G + R + L+ G I P ++EN VA+ V GE ++AF++ Sbjct: 468 DGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVV 525 >gi|157311624 acyl-CoA synthetase medium-chain family member 2B [Homo sapiens] Length = 577 Score = 60.1 bits (144), Expect = 7e-09 Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 15/164 (9%) Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEG 506 RA G E YGQTE C ++ G++G C ++++D ++ N + EG Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVID-DKGNVLPPGTEG 408 Query: 507 EVCVKGP-----NVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFK 561 ++ ++ +F GY+++P KTA + D WL GD G +G + + R I Sbjct: 409 DIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467 Query: 562 LAQGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598 + G I P ++EN M+ V + V GE ++AF+I Sbjct: 468 -SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510 >gi|157311622 acyl-CoA synthetase medium-chain family member 2B [Homo sapiens] Length = 577 Score = 60.1 bits (144), Expect = 7e-09 Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 15/164 (9%) Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEG 506 RA G E YGQTE C ++ G++G C ++++D ++ N + EG Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVID-DKGNVLPPGTEG 408 Query: 507 EVCVKGP-----NVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFK 561 ++ ++ +F GY+++P KTA + D WL GD G +G + + R I Sbjct: 409 DIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467 Query: 562 LAQGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598 + G I P ++EN M+ V + V GE ++AF+I Sbjct: 468 -SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510 >gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo sapiens] Length = 577 Score = 59.7 bits (143), Expect = 9e-09 Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 15/164 (9%) Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEG 506 RA G E YGQTE C ++ G++G C ++++D ++ N + EG Sbjct: 350 RAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIID-DKGNVLPPGTEG 408 Query: 507 EVCVKGP-----NVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFK 561 ++ ++ +F GY+ +P KTA + D WL GD G +G + + R I Sbjct: 409 DIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467 Query: 562 LAQGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598 + G I P ++EN M V + V GE ++AF++ Sbjct: 468 -SSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVV 510 >gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo sapiens] Length = 580 Score = 57.8 bits (138), Expect = 3e-08 Identities = 50/183 (27%), Positives = 84/183 (45%), Gaps = 15/183 (8%) Query: 428 VRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCN 487 +R +TG P++ VL R G + YEGYGQTE C + G +G M Sbjct: 340 LRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPY 399 Query: 488 LIKLVDVEEMNYMAAEGEGEVCVK-GPN----VFQGYLKDPAKTAEALDKDGWLHTGDIG 542 ++++D E N + EGE+ ++ P F Y+ +P KTA + D ++ TGD G Sbjct: 400 DVQIID-ENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYV-TGDRG 457 Query: 543 KWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFV-------HGESLQA 595 +G + R + ++ G I P ++E+ + V + V GE ++A Sbjct: 458 VMDSDGYFWFVGRADDVI-ISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKA 516 Query: 596 FLI 598 F++ Sbjct: 517 FVV 519 >gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo sapiens] Length = 579 Score = 47.8 bits (112), Expect = 4e-05 Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 15/183 (8%) Query: 428 VRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCN 487 +R +TG ++ V + G + YEGYGQ+E C +G +G P Sbjct: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399 Query: 488 LIKLVDVEEMNYMAAEGEGEVCVK-GPN----VFQGYLKDPAKTAEALDKDGWLHTGDIG 542 +++VD +E N + EG V V+ P F YL +P KTA + D ++ TGD Sbjct: 400 DVQIVD-DEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYI-TGDRA 457 Query: 543 KWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFV-------HGESLQA 595 + +G + R + + I P ++E+ V + V GE ++A Sbjct: 458 RMDKDGYFWFMGRNDDVIN-SSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKA 516 Query: 596 FLI 598 F++ Sbjct: 517 FIV 519 >gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase ACSM2B, mitochondrial isoform 2 [Homo sapiens] Length = 571 Score = 47.0 bits (110), Expect = 6e-05 Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 17/162 (10%) Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYM-AAEGE 505 RA G E YGQTE C ++ G++G C DV+ + ++ + Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASC-----YDVQVIAFVHGSPRA 404 Query: 506 GEVCVKGPNV--FQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLA 563 G++ G F G+ ++P KTA + D WL GD G +G + + R I + Sbjct: 405 GDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN-S 462 Query: 564 QGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598 G I P ++EN M+ V + V GE ++AF+I Sbjct: 463 SGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504 >gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase ACSM2B, mitochondrial isoform 1 [Homo sapiens] Length = 571 Score = 47.0 bits (110), Expect = 6e-05 Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 17/162 (10%) Query: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYM-AAEGE 505 RA G E YGQTE C ++ G++G C DV+ + ++ + Sbjct: 350 RAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASC-----YDVQVIAFVHGSPRA 404 Query: 506 GEVCVKGPNV--FQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLA 563 G++ G F G+ ++P KTA + D WL GD G +G + + R I + Sbjct: 405 GDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN-S 462 Query: 564 QGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598 G I P ++EN M+ V + V GE ++AF+I Sbjct: 463 SGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504 >gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo sapiens] Length = 577 Score = 46.2 bits (108), Expect = 1e-04 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 15/160 (9%) Query: 451 GCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEV-- 508 G YE YGQ+E C G +G P ++++D ++ + + EG + Sbjct: 360 GLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVID-DKGSILPPNTEGNIGI 418 Query: 509 ---CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQG 565 V+ ++F Y DP KTA+ ++ + +TGD GK G + + R I A G Sbjct: 419 RIKPVRPVSLFMCYEGDPEKTAK-VECGDFYNTGDRGKMDEEGYICFLGRSDDIIN-ASG 476 Query: 566 EYIAPEKIENIYMRSEPVAQVFV-------HGESLQAFLI 598 I P ++E+ + VA+ V GE ++AF++ Sbjct: 477 YRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIV 516 Score = 38.9 bits (89), Expect = 0.016 Identities = 48/203 (23%), Positives = 76/203 (37%), Gaps = 50/203 (24%) Query: 110 GSRKPDQPYEWL---------SYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEW 160 G R P+ + W+ S++++ +L+ + + Q D + + PEW Sbjct: 66 GKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDH-LALMLPRVPEW 124 Query: 161 VIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPG 220 ++ GC ++ +P L + I Y + +LS Sbjct: 125 WLVAVGCMRTGIIFIPATILLKAKDILY---RLQLSKA---------------------- 159 Query: 221 LKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRAN----RRKPKPPAPE-------- 268 K IV +DA SE+ +C T + + D R R K +PE Sbjct: 160 -KGIVTIDALASEVDSIASQCPSLKTKL-LVSDHSREGWLDFRSLVKSASPEHTCVKSKT 217 Query: 269 -DLAVICFTSGTTGNPKGAMVTH 290 D VI FTSGTTG PK A +H Sbjct: 218 LDPMVIFFTSGTTGFPKMAKHSH 240 >gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo sapiens] Length = 480 Score = 43.9 bits (102), Expect = 5e-04 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 2/105 (1%) Query: 408 NNSLWDRLIFHKVQSSLGGR-VRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAG 466 N ++ L+ HK +S + ++ V P+S V+ + YEGYGQTE Sbjct: 317 NPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRITKLDIYEGYGQTETGLL 376 Query: 467 CCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVK 511 C + +G P+P ++++VD E N + EG + ++ Sbjct: 377 CATSKTIKLKPSSLGKPLPPYIVQIVD-ENSNLLPPGEEGNIAIR 420 >gi|13325057 solute carrier family 27 (fatty acid transporter), member 5 [Homo sapiens] Length = 690 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 14/86 (16%) Query: 254 LGRANRRKPKPPAPEDL---------AVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKAT 304 LG A P P P DL A+ +TSGTTG PK A++TH ++ S + + Sbjct: 264 LGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVL-QMSKMLSLS 322 Query: 305 ENTVNPCPDDTLISFLPLAHMFERVV 330 T DD + + LPL H+ VV Sbjct: 323 GATA----DDVVYTVLPLYHVMGLVV 344 >gi|13236579 solute carrier family 27 member 3 [Homo sapiens] Length = 730 Score = 36.2 bits (82), Expect = 0.11 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 5/62 (8%) Query: 264 PPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLA 323 P + D + FTSGTTG PK A ++H I+ C F + +D + LPL Sbjct: 323 PQSITDTCLYIFTSGTTGLPKAARISHLKIL-QCQGFYQ----LCGVHQEDVIYLALPLY 377 Query: 324 HM 325 HM Sbjct: 378 HM 379 >gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens] Length = 1098 Score = 34.3 bits (77), Expect = 0.40 Identities = 53/242 (21%), Positives = 88/242 (36%), Gaps = 26/242 (10%) Query: 150 IGIFAQ---NRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKA 206 IG++ Q + P W++ G VP+ T+ + K L + V+K + Sbjct: 61 IGLYCQPGIDLPSWIL---GILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQIN 117 Query: 207 KL-----LLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRK 261 K L + + +++ + + V G E + ++ + + + Sbjct: 118 KFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNE 177 Query: 262 PKPPAPEDL------AVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDT 315 K DL A + TSGTTG PK V H+ IV + F + T +D Sbjct: 178 EKAEEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDIT----QEDV 233 Query: 316 LISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVL-----QPTVFPVVPRLL 370 L PL V + L GA + ++LL L + + TV P LL Sbjct: 234 LFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLL 293 Query: 371 NR 372 R Sbjct: 294 RR 295 >gi|40807357 solute carrier family 27 (fatty acid transporter), member 4 [Homo sapiens] Length = 643 Score = 34.3 bits (77), Expect = 0.40 Identities = 54/228 (23%), Positives = 88/228 (38%), Gaps = 30/228 (13%) Query: 122 SYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTL 181 +++Q+ E S + + L +G A IF +NR E+V + G + + L Sbjct: 103 TFRQLDEYSSSVANFLQARGL--ASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNL 160 Query: 182 GNEAITYIVNKAEL-SLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR 240 +A+ + + + +LVF E A + E V L P L + Sbjct: 161 RRDALLHCLTTSRARALVFGS--EMASAICE-VHASLDPSLSLFC----------SGSWE 207 Query: 241 CGVEVTSMKAMEDLGRANRRKPKPPAPE----DLAVICFTSGTTGNPKGAMVTHRNIVSD 296 G S + ++ L + + K P P+ D +TSGTTG PK A+V H Sbjct: 208 PGAVPPSTEHLDPLLK-DAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRM 266 Query: 297 CSAFVKATENTVNPCPDDTLISFLPLAHMFERVV---ECVMLCHGAKI 341 + P+D + LPL H +V +C L HG + Sbjct: 267 AALVYYGFRMR----PNDIVYDCLPLYHSAGNIVGIGQC--LLHGMTV 308 >gi|227499619 solute carrier family 27 (fatty acid transporter), member 2 isoform 1 [Homo sapiens] Length = 620 Score = 33.9 bits (76), Expect = 0.52 Identities = 14/23 (60%), Positives = 18/23 (78%) Query: 271 AVICFTSGTTGNPKGAMVTHRNI 293 A+ +TSGTTG PK AM+TH+ I Sbjct: 220 ALYIYTSGTTGLPKAAMITHQRI 242 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.139 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,037,550 Number of Sequences: 37866 Number of extensions: 1232583 Number of successful extensions: 2555 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 14 Number of HSP's that attempted gapping in prelim test: 2447 Number of HSP's gapped (non-prelim): 63 length of query: 698 length of database: 18,247,518 effective HSP length: 109 effective length of query: 589 effective length of database: 14,120,124 effective search space: 8316753036 effective search space used: 8316753036 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.