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Search of human proteins with 40538788
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
(816 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 1695 0.0
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 1656 0.0
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 1656 0.0
gi|51593088 neuroligin 3 [Homo sapiens] 1212 0.0
gi|7662470 neuroligin 1 [Homo sapiens] 1201 0.0
gi|30840978 neuroligin 2 [Homo sapiens] 1016 0.0
gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 322 9e-88
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 313 5e-85
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 311 1e-84
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 288 2e-77
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 286 7e-77
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 286 7e-77
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 285 2e-76
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 285 2e-76
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 281 2e-75
gi|33563374 carboxylesterase 3 [Homo sapiens] 280 5e-75
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 274 3e-73
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 237 3e-62
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 227 3e-59
gi|55770862 thyroglobulin [Homo sapiens] 189 7e-48
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 150 4e-36
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 150 4e-36
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 89 2e-17
gi|194394146 dipeptidylpeptidase 9 [Homo sapiens] 36 0.16
gi|11055976 carbohydrate (N-acetylglucosamine 6-O) sulfotransfer... 34 0.48
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 32 2.4
gi|116284392 mucin 2 precursor [Homo sapiens] 32 3.1
gi|29029632 anaplastic lymphoma kinase [Homo sapiens] 31 5.3
gi|19923790 rab3 GTPase-activating protein, non-catalytic subuni... 31 5.3
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 30 6.9
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 1695 bits (4390), Expect = 0.0
Identities = 816/816 (100%), Positives = 816/816 (100%)
Query: 1 MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRT 60
MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRT
Sbjct: 1 MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRT 60
Query: 61 PLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLL 120
PLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLL
Sbjct: 61 PLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLL 120
Query: 121 HDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG 180
HDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG
Sbjct: 121 HDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG 180
Query: 181 TGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
TGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA
Sbjct: 181 TGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
Query: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL
Sbjct: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
Query: 301 ADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
ADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG
Sbjct: 301 ADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
Query: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI
Sbjct: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
Query: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM
Sbjct: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
Query: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV
Sbjct: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
Query: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL
Sbjct: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
Query: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED
Sbjct: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
Query: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTND 720
TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTND
Sbjct: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTND 720
Query: 721 ITHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPFMTPNTIT 780
ITHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPFMTPNTIT
Sbjct: 721 ITHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPFMTPNTIT 780
Query: 781 MIPNTLMGMQPLHTFKTFSGGQNSTNLPHGHSTTRV 816
MIPNTLMGMQPLHTFKTFSGGQNSTNLPHGHSTTRV
Sbjct: 781 MIPNTLMGMQPLHTFKTFSGGQNSTNLPHGHSTTRV 816
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 1656 bits (4289), Expect = 0.0
Identities = 796/816 (97%), Positives = 803/816 (98%)
Query: 1 MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRT 60
M RPQGLLWLPLLFT VCVMLNSNVLLW+TALAIKFTLIDSQAQYPVVNTNYGKI+GLRT
Sbjct: 1 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT 60
Query: 61 PLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLL 120
PLP+EILGPVEQYLGVPYASPPTGERRFQPPE PSSWTGIRN TQF+AVCPQHLDER LL
Sbjct: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL 120
Query: 121 HDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG 180
HDMLPIWFT +LDTLMTYVQDQNEDCLYLNIYVP EDDIH+QNSKKPVMVYIHGGSYMEG
Sbjct: 121 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG 180
Query: 181 TGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
TGNMIDGSILASYGNVIVITIN RLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA
Sbjct: 181 TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
Query: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL
Sbjct: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
Query: 301 ADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
ADKVGCNMLDTTDMVECL+NKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG
Sbjct: 301 ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
Query: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI
Sbjct: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
Query: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM
Sbjct: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
Query: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV
Sbjct: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
Query: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL
Sbjct: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
Query: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED
Sbjct: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
Query: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTND 720
TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHR PSPQRNTTND
Sbjct: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTND 720
Query: 721 ITHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPFMTPNTIT 780
I HIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIP MTPNTIT
Sbjct: 721 IAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTIT 780
Query: 781 MIPNTLMGMQPLHTFKTFSGGQNSTNLPHGHSTTRV 816
MIPNTL GMQPLHTF TFSGGQNSTNLPHGHSTTRV
Sbjct: 781 MIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV 816
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 1656 bits (4289), Expect = 0.0
Identities = 796/816 (97%), Positives = 803/816 (98%)
Query: 1 MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRT 60
M RPQGLLWLPLLFT VCVMLNSNVLLW+TALAIKFTLIDSQAQYPVVNTNYGKI+GLRT
Sbjct: 1 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT 60
Query: 61 PLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLL 120
PLP+EILGPVEQYLGVPYASPPTGERRFQPPE PSSWTGIRN TQF+AVCPQHLDER LL
Sbjct: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL 120
Query: 121 HDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG 180
HDMLPIWFT +LDTLMTYVQDQNEDCLYLNIYVP EDDIH+QNSKKPVMVYIHGGSYMEG
Sbjct: 121 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG 180
Query: 181 TGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
TGNMIDGSILASYGNVIVITIN RLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA
Sbjct: 181 TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
Query: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL
Sbjct: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
Query: 301 ADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
ADKVGCNMLDTTDMVECL+NKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG
Sbjct: 301 ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
Query: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI
Sbjct: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
Query: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM
Sbjct: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
Query: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV
Sbjct: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
Query: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL
Sbjct: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
Query: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED
Sbjct: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
Query: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTND 720
TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHR PSPQRNTTND
Sbjct: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTND 720
Query: 721 ITHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPFMTPNTIT 780
I HIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIP MTPNTIT
Sbjct: 721 IAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTIT 780
Query: 781 MIPNTLMGMQPLHTFKTFSGGQNSTNLPHGHSTTRV 816
MIPNTL GMQPLHTF TFSGGQNSTNLPHGHSTTRV
Sbjct: 781 MIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV 816
>gi|51593088 neuroligin 3 [Homo sapiens]
Length = 828
Score = 1212 bits (3135), Expect = 0.0
Identities = 586/811 (72%), Positives = 674/811 (83%), Gaps = 29/811 (3%)
Query: 27 LWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGER 86
LW +LA++ + +QA P VNT++GK++G R PLPSEILGPV+QYLGVPYA+PP GE+
Sbjct: 26 LWFLSLALRAS---TQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEK 82
Query: 87 RFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDC 146
RF PPE P SW+GIRNAT F VCPQ++ + MLP+WFT +LD + TY+Q+ NEDC
Sbjct: 83 RFLPPEPPPSWSGIRNATHFPPVCPQNIHTA-VPEVMLPVWFTANLDIVATYIQEPNEDC 141
Query: 147 LYLNIYVPMED--------------------DIHEQNSKKPVMVYIHGGSYMEGTGNMID 186
LYLN+YVP ED DI + +K PVMVYIHGGSYMEGTGNMID
Sbjct: 142 LYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAK-PVMVYIHGGSYMEGTGNMID 200
Query: 187 GSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 246
GSILASYGNVIVIT+N R+G+LGFLSTGDQAAKGNYGLLDQIQALRW+ EN+ FGGDP+
Sbjct: 201 GSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPR 260
Query: 247 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGC 306
R+T+FGSG GASCVSLLTLSH+SEGLFQ+AIIQSG+ALSSWAVNYQP KYT +LADKVGC
Sbjct: 261 RITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGC 320
Query: 307 NMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYD 366
N+LDT DMV+CL+ K+ KEL++Q I PA YH+AFGPVIDGDVIPDDP+ILMEQGEFLNYD
Sbjct: 321 NVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYD 380
Query: 367 IMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTD 426
IMLGVNQGEGLKFV+G+VD EDGV+ DFD+SVSNFVDNLYGYPEGKDTLRETIKFMYTD
Sbjct: 381 IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTD 440
Query: 427 WADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWAD 486
WAD++NPETRRKTLVALFTDHQWV P+V TADLHA+YGSPTYFYAFYHHCQS MKP+W+D
Sbjct: 441 WADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSD 500
Query: 487 SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKF 546
+AHGDEVPYVFG+PM+GPT+LF CNFSKNDVMLSAVVMTYWTNFAKTGDPN+PVPQDTKF
Sbjct: 501 AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKF 560
Query: 547 IHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
IHTK NRFEEVAWSKYNP+DQLYLHIGLKPRVRDHYRATKVAFW LVPHL+NL+++F Y
Sbjct: 561 IHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHY 620
Query: 607 VSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIE 666
STTTKVPPPD T + TRR K W +TKRPAI+PA + ++++ + +L+E
Sbjct: 621 TSTTTKVPPPDTTHSSHITRRPNGKTW-STKRPAISPAYSNENAQGSWNGDQDAGPLLVE 679
Query: 667 TKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNT-TNDITHIQ 725
RDYSTELSVTIAVGASLLFLN+LAFAALYY+KDKRR E R PSPQR ++
Sbjct: 680 NPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAP 739
Query: 726 NEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPFMTPNTITMIPNT 785
EE+ +LQ+ HECE+ HDTLRLT PDYTLTLRRSPDDIP MTPNTITMIPN+
Sbjct: 740 EEELAALQLGPTH--HECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNS 797
Query: 786 LMGMQPLHTFKTFSGGQNSTNLPHGHSTTRV 816
L+G+Q LH + TF+ G NST LPH HSTTRV
Sbjct: 798 LVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV 828
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 1201 bits (3108), Expect = 0.0
Identities = 581/789 (73%), Positives = 658/789 (83%), Gaps = 36/789 (4%)
Query: 46 PVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQ 105
P+V TN+GKI+G++ L +EILGPV Q+LGVPYA+PPTGERRFQPPE PS W+ IRNATQ
Sbjct: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
Query: 106 FSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSK 165
F+ VCPQ++ + L MLP+WFT +LD + +YVQDQ+EDCLYLNIYVP EDDI +
Sbjct: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172
Query: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLL 225
KPVMVYIHGGSYMEGTGN+ DGS+LASYGNVIVIT+N RLG+LGFLSTGDQAAKGNYGLL
Sbjct: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232
Query: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEG---------LFQKA 276
D IQALRW EN+G FGGDP R+T+FGSGAG SCV+LLTLSHYSEG LFQ+A
Sbjct: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292
Query: 277 IIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATY 336
I QSGTALSSWAV++QPAKY R+LA KVGCN+ DT ++VECL+ K YKEL+ Q I PA Y
Sbjct: 293 IAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARY 352
Query: 337 HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFD 396
HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV+ IVD++DG++ +DFD
Sbjct: 353 HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFD 412
Query: 397 FSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVAT 456
F+VSNFVDNLYGYPEGKD LRETIKFMYTDWAD+ NPETRRKTL+ALFTDHQWVAPAVAT
Sbjct: 413 FAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVAT 472
Query: 457 ADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKND 516
ADLH+ +GSPTYFYAFYHHCQ++ P+WAD+AHGDEVPYV GIPMIGPTELF CNFSKND
Sbjct: 473 ADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKND 532
Query: 517 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP 576
VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAW++Y+ KDQLYLHIGLKP
Sbjct: 533 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKP 592
Query: 577 RVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKI---W 633
RV++HYRA KV WLELVPHLHNLN+I QY STTTKVP D+T P TR++ + +
Sbjct: 593 RVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRP--TRKNSVPVTSAF 650
Query: 634 PTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAF 693
PT K+ ++PK P +RDYSTELSVTIAVGASLLFLNILAF
Sbjct: 651 PTAKQ------DDPKQQPSPFSV----------DQRDYSTELSVTIAVGASLLFLNILAF 694
Query: 694 AALYYKKDKRRHETHRHPSPQRNTTNDITHIQNEEIMSLQMKQLEHDHECESLQAHD-TL 752
AALYYKKDKRRH+ HR SPQR TTND+TH Q EEIMSLQMK + DHECES+ H+ L
Sbjct: 695 AALYYKKDKRRHDVHRRCSPQRTTTNDLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVL 754
Query: 753 RLTCPPDYTLTLRRSPDDIPFMTPNTITMIPNTLMGMQPLHTFKTFSGGQNST-----NL 807
R CPPDYTL +RRSPDD+P MTPNTITMIPNT+ G+QPLHTF TF+GGQN+T
Sbjct: 755 RTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPH 814
Query: 808 PHGHSTTRV 816
PH HSTTRV
Sbjct: 815 PHSHSTTRV 823
>gi|30840978 neuroligin 2 [Homo sapiens]
Length = 835
Score = 1016 bits (2627), Expect = 0.0
Identities = 511/816 (62%), Positives = 613/816 (75%), Gaps = 59/816 (7%)
Query: 42 QAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIR 101
+ ++PVVNT YG+++G+R L +EILGPV Q+LGVPYA+PP G RRFQPPE+P+SW G+R
Sbjct: 38 EERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVR 97
Query: 102 NATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMED---- 157
NAT CPQ+L L MLP+WFT +L+ TYVQ+Q+EDCLYLN+YVP ED
Sbjct: 98 NATTLPPACPQNLHGA-LPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLT 156
Query: 158 -------------DIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCR 204
DI + KKPVM+++HGGSYMEGTGNM DGS+LA+YGNVIV T+N R
Sbjct: 157 KKRDEATLNPPDTDIRDPG-KKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYR 215
Query: 205 LGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLT 264
LG+LGFLSTGDQAAKGNYGLLDQIQALRW+ EN+ FGGDP+R+TIFGSGAGASCV+LL
Sbjct: 216 LGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLI 275
Query: 265 LSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYK 324
LSH+SEGLFQKAI QSGTA+SSW+VNYQP KYTR+LA KVGC+ D+ + VECL+ K +
Sbjct: 276 LSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSR 335
Query: 325 ELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIV 384
EL+ Q + PA YHIAFGPV+DGDV+PDDP+ILM+QGEFLNYD+++GVNQGEGLKFV+
Sbjct: 336 ELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSA 395
Query: 385 DNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALF 444
++EDGV+ + FDF+VSNFVDNLYGYPEGKD LRETIKFMYTDWAD++N E RRKTL+ALF
Sbjct: 396 ESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALF 455
Query: 445 TDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGP 504
TDHQWVAPAVATA LHA Y SP YFY FYHHCQ+E +P WAD+AHGDE+PYVFG+PM+G
Sbjct: 456 TDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGA 515
Query: 505 TELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNP 564
T+LF CNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEV WSK+N
Sbjct: 516 TDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNS 575
Query: 565 KDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLN-EIFQYVSTTTKVPPPDMTSFPY 623
K++ YLHIGLKPRVRD+YRA KVAFWLELVPHLHNL+ E+F +TTT++P PY
Sbjct: 576 KEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELF---TTTTRLP-------PY 625
Query: 624 GTR---RSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIA 680
TR R PA P T+RP P+ +P GP RDYSTELSVT+A
Sbjct: 626 ATRWPPRPPAGA-PGTRRPPPPATLPPEPEPEP---GPRAYDRFPGDSRDYSTELSVTVA 681
Query: 681 VGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTNDITHIQNEEIMSLQMKQLEHD 740
VGASLLFLNILAFAALYYK+D+R+ R SP + + + ++ ++L +
Sbjct: 682 VGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVP--GGGPLLPAAGRELPPE 739
Query: 741 HECESLQAH----------DTLRLTCPPDYTLTLRRSPDDIPFMTPNTITMIPNTLMGMQ 790
E SLQ + LR CPPDYTL LRR+PDD+P + P +T++P+ L
Sbjct: 740 EELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPP 799
Query: 791 P-----LHTFKTF-----SGGQNSTNLPHGHSTTRV 816
P LH F F + ++ LPH HSTTRV
Sbjct: 800 PPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV 835
>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
Length = 602
Score = 322 bits (825), Expect = 9e-88
Identities = 189/564 (33%), Positives = 298/564 (52%), Gaps = 56/564 (9%)
Query: 47 VVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQF 106
++ T GK++G+ + G V +LG+PYA PP G RF+ P+S + W+ I NAT++
Sbjct: 33 IIATKNGKVRGMNLTVFG---GTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKY 89
Query: 107 SAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKK 166
+ C Q++D+ F +W + D +EDCLYLN+++P +
Sbjct: 90 ANSCCQNIDQSFPGFHGSEMWNPNT---------DLSEDCLYLNVWIPAP-----KPKNA 135
Query: 167 PVMVYIHGGSYMEGTGNM--IDGSILASYGNVIVITINCRLGILGFLST-GDQAAKGNYG 223
V+++I+GG + GT ++ DG LA VIV+++N R+G LGFL+ G+ A GN G
Sbjct: 136 TVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMG 195
Query: 224 LLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTA 283
L DQ AL+W+++N+ AFGG+PK VT+FG AGA+ VSL LS S LF +AI+QSG+
Sbjct: 196 LFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSF 255
Query: 284 LSSWAVN--YQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATY----H 337
+ WAV Y+ T LA GC+ + T++++CL+NK+ +E++ Y
Sbjct: 256 NAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLS 315
Query: 338 IAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV-----DGIVDNEDGVTP 392
+ FGP +DGD + D P IL+E G+F I++GVN+ EG F+ DN +T
Sbjct: 316 VNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITR 375
Query: 393 NDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAP 452
+F + F +P + +E+I F YTDW D + PE R+ L + D+ ++ P
Sbjct: 376 KEFQEGLKIF------FPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICP 429
Query: 453 AVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNF 512
A+ +++G+ +FY F H P W HG E+ +VFG+P+ N+
Sbjct: 430 ALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRD-----NY 484
Query: 513 SKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHI 572
+K + +LS ++ W NFAK G+PN+ T +W + +Q YL +
Sbjct: 485 TKAEEILSRSIVKRWANFAKYGNPNETQNNST-------------SWPVFKSTEQKYLTL 531
Query: 573 GLK-PRVRDHYRATKVAFWLELVP 595
+ R+ RA + FW P
Sbjct: 532 NTESTRIMTKLRAQQCRFWTSFFP 555
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 313 bits (801), Expect = 5e-85
Identities = 208/643 (32%), Positives = 311/643 (48%), Gaps = 74/643 (11%)
Query: 1 MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRT 60
M PQ LL P L + + ++L LW+ + + +V G+++G+R
Sbjct: 1 MRPPQCLLHTPSLASPLLLLL-----LWLLGGGVGAE--GREDAELLVTVRGGRLRGIRL 53
Query: 61 PLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLL 120
P GPV +LG+P+A PP G RRF PPE W+G+ +AT F +VC Q++D +
Sbjct: 54 KTPG---GPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPG 110
Query: 121 HDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG 180
+ +W ++ +EDCLYLN++ P S PV+V+I+GG + G
Sbjct: 111 FEGTEMWNPN---------RELSEDCLYLNVWTPYP----RPTSPTPVLVWIYGGGFYSG 157
Query: 181 TGNM--IDGSILASYGNVIVITINCRLGILGFLST-GDQAAKGNYGLLDQIQALRWIEEN 237
++ DG L +++++N R+G GFL+ G + A GN GLLDQ AL+W++EN
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217
Query: 238 VGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAV--NYQPAK 295
V AFGGDP VT+FG AGA+ V + LS S GLF +A++QSG WA + +
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277
Query: 296 YTRILADKVGCNMLDT----TDMVECLKNKNYKELIQQT--ITP--ATYHIAFGPVIDGD 347
LA VGC T T++V CL+ + + L+ + P + + +F PV+DGD
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337
Query: 348 VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV-----DGIVDNEDGVTPNDFDFSVSNF 402
+ D P+ L+ G+F +++GV + EG F+ DNE ++ +F V
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVR-- 395
Query: 403 VDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQ 462
G P+ D E + YTDW E+P R+ L + DH V P A A
Sbjct: 396 ----VGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAA 451
Query: 463 YGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAV 522
G+ Y Y F H + P W HG E+ ++FGIP+ S N++ + + +
Sbjct: 452 QGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDP-----SRNYTAEEKIFAQR 506
Query: 523 VMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP-RVRDH 581
+M YW NFA+TGDPN+ P+D K W Y Q Y+ + L+P VR
Sbjct: 507 LMRYWANFARTGDPNE--PRDPK----------APQWPPYTAGAQQYVSLDLRPLEVRRG 554
Query: 582 YRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYG 624
RA AFW +P L +S T P F +G
Sbjct: 555 LRAQACAFWNRFLPKL---------LSATASEAPSTCPGFTHG 588
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 311 bits (798), Expect = 1e-84
Identities = 203/616 (32%), Positives = 304/616 (49%), Gaps = 65/616 (10%)
Query: 1 MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRT 60
M PQ LL P L + + ++L LW+ + + +V G+++G+R
Sbjct: 1 MRPPQCLLHTPSLASPLLLLL-----LWLLGGGVGAE--GREDAELLVTVRGGRLRGIRL 53
Query: 61 PLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLL 120
P GPV +LG+P+A PP G RRF PPE W+G+ +AT F +VC Q++D +
Sbjct: 54 KTPG---GPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPG 110
Query: 121 HDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG 180
+ +W ++ +EDCLYLN++ P S PV+V+I+GG + G
Sbjct: 111 FEGTEMWNPN---------RELSEDCLYLNVWTPYP----RPTSPTPVLVWIYGGGFYSG 157
Query: 181 TGNM--IDGSILASYGNVIVITINCRLGILGFLST-GDQAAKGNYGLLDQIQALRWIEEN 237
++ DG L +++++N R+G GFL+ G + A GN GLLDQ AL+W++EN
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217
Query: 238 VGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAV--NYQPAK 295
V AFGGDP VT+FG AGA+ V + LS S GLF +A++QSG WA + +
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277
Query: 296 YTRILADKVGCNMLDT----TDMVECLKNKNYKELIQQT--ITP--ATYHIAFGPVIDGD 347
LA VGC T T++V CL+ + + L+ + P + + +F PV+DGD
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337
Query: 348 VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV-----DGIVDNEDGVTPNDFDFSVSNF 402
+ D P+ L+ G+F +++GV + EG F+ DNE ++ +F V
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVR-- 395
Query: 403 VDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQ 462
G P+ D E + YTDW E+P R+ L + DH V P A A
Sbjct: 396 ----VGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAA 451
Query: 463 YGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAV 522
G+ Y Y F H + P W HG E+ ++FGIP+ S N++ + + +
Sbjct: 452 QGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDP-----SRNYTAEEKIFAQR 506
Query: 523 VMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP-RVRDH 581
+M YW NFA+TGDPN+ P+D K W Y Q Y+ + L+P VR
Sbjct: 507 LMRYWANFARTGDPNE--PRDPK----------APQWPPYTAGAQQYVSLDLRPLEVRRG 554
Query: 582 YRATKVAFWLELVPHL 597
RA AFW +P L
Sbjct: 555 LRAQACAFWNRFLPKL 570
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 288 bits (736), Expect = 2e-77
Identities = 189/578 (32%), Positives = 292/578 (50%), Gaps = 61/578 (10%)
Query: 31 ALAIKFTLIDSQAQ---YPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERR 87
A + L+ Q Q P+ T+ G++ G + G V+ +LG+P+A PP G R
Sbjct: 78 ACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLR 136
Query: 88 FQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQ-NEDC 146
F PPE P SW+G+R+ T A+C L D+ + MT+ D +EDC
Sbjct: 137 FAPPEPPESWSGVRDGTTHPAMC---------LQDLTAVESEFLSQFNMTFPSDSMSEDC 187
Query: 147 LYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLG 206
LYL+IY P + S PVMV+IHGG+ + G ++ DGS+LA+ NV+V+ I RLG
Sbjct: 188 LYLSIYTPAHS---HEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLG 244
Query: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266
+LGF STGD+ A GN+G LDQ+ ALRW+++N+ FGG+P RVTIFG AG + VS L +S
Sbjct: 245 VLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVS 304
Query: 267 HYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKEL 326
S+GLF AI++SG AL + + ++A+ C+ +D+ +V CL+ K+ +E+
Sbjct: 305 PISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEI 364
Query: 327 IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG---LKFVDGI 383
+ + + G V+DG +P PQ L+ +F ++GVN E + V I
Sbjct: 365 L---AINKPFKMIPG-VVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420
Query: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443
D + + ++ + L P D LRE D +P+T + +
Sbjct: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY------IGDNGDPQTLQAQFQEM 474
Query: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQ--SEMKPSWADSAHGDEVPYVFGIPM 501
D +V PA+ A +P YFY F H ++P + HGDE+P+VF
Sbjct: 475 MADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVF---- 529
Query: 502 IGPTELFSCN---FSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEV 557
F N F++ + LS +M YW NFA+ G+PN + +P
Sbjct: 530 ---RSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH--------------- 571
Query: 558 AWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
W ++ ++Q YL + L+P V +A ++ FW + +P
Sbjct: 572 -WPLFDQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 607
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 286 bits (731), Expect = 7e-77
Identities = 190/564 (33%), Positives = 285/564 (50%), Gaps = 54/564 (9%)
Query: 46 PVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQ 105
PVV+T +GK+ G L PV +LG+P+A PP G RF PP+ W+ ++NAT
Sbjct: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
Query: 106 FSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSK 165
+ +C Q LL ++ FT + + + +EDCLYLNIY P D+ ++N +
Sbjct: 83 YPPMCTQDPKAGQLLSEL----FTNRKENIPLKL---SEDCLYLNIYTPA--DLTKKN-R 132
Query: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLL 225
PVMV+IHGG M G + DG LA++ NV+V+TI RLGI GF STGD+ ++GN+G L
Sbjct: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
Query: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 285
DQ+ ALRW+++N+ +FGG+P VTIFG AG VS+L LS ++ LF +AI +SG AL+
Sbjct: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 252
Query: 286 SWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTI-----------TP 333
S V K +A GC + MV CL+ K +EL++ T+ P
Sbjct: 253 SVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDP 312
Query: 334 ATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPN 393
G VIDG ++ P+ L + F M+G+N+ E + ++
Sbjct: 313 RESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQL 372
Query: 394 DFDFSVSNFVDNLYGYPEGKDTLRE-TIKFMYTDWADKENPETRRKTLVALFTDHQWVAP 452
D ++S + K+ + E T K++ ++ ++ + L D + P
Sbjct: 373 DQKTAMSLLWKSYPLVCIAKELIPEATEKYL----GGTDDTVKKKDLFLDLIADVMFGVP 428
Query: 453 AVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSC 510
+V A H G+PTY Y F + S+MKP HGDE+ VFG P +
Sbjct: 429 SVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE------ 482
Query: 511 NFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLY 569
S+ ++ LS +VM +W NFA+ G+PN + +P W +YN K+ Y
Sbjct: 483 GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WPEYNQKEG-Y 525
Query: 570 LHIGLKPRVRDHYRATKVAFWLEL 593
L IG + + +VAFW L
Sbjct: 526 LQIGANTQAAQKLKDKEVAFWTNL 549
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 286 bits (731), Expect = 7e-77
Identities = 192/574 (33%), Positives = 295/574 (51%), Gaps = 50/574 (8%)
Query: 27 LWITALAIKFTLIDSQAQYPVVNTNYGKIQGLR-TPLPSEILGPVEQYLGVPYASPPTGE 85
+W+ A K A+ P NT G IQG + T L S + PV +LGVP+A+PP G
Sbjct: 16 IWVLAAPTK----GPSAEGPQRNTRLGWIQGKQVTVLGSPV--PVNVFLGVPFAAPPLGS 69
Query: 86 RRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNED 145
RF P+ S W +R AT + +C Q+ + L ML + + +ED
Sbjct: 70 LRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKF---------GVSED 120
Query: 146 CLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRL 205
CLYLNIY P D SK PV+V+ GG++ G+ ++ DGS LA+Y +V+V+ + RL
Sbjct: 121 CLYLNIYAPAHADT---GSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177
Query: 206 GILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTL 265
GI GF +T DQ A GN+ DQ+ AL W+++N+ FGGDP VTIFG AGA VS L L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237
Query: 266 SHYSEGLFQKAIIQSGTALSSW--AVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNY 323
S ++GLF KAI++SG A+ + A +Y+ ++ +++A G N D+ ++ CL+ K
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPS 297
Query: 324 KELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI 383
KEL+ T++ T +F V+DG P++P L+ Q F ++GVN E F+ +
Sbjct: 298 KELL--TLSQKTK--SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE-CGFLLPM 352
Query: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443
+ + ++ ++ ++ + + N+ P L F DK + R +L+ L
Sbjct: 353 KEAPEILSGSNKSLAL-HLIQNILHIPPQYLHLVANEYF-----HDKHSLTEIRDSLLDL 406
Query: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYH--HCQSEMKPSWADSAHGDEVPYVFGIPM 501
D +V PA+ TA H G+P YFY F H C + KP++ + H DEV +VFG
Sbjct: 407 LGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAF 466
Query: 502 IGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSK 561
+ + ++ + +LS +M YW FA+TG+PN + W
Sbjct: 467 LKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGN---------------DLSLWPA 511
Query: 562 YNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
YN +Q YL + L + + +V FW +P
Sbjct: 512 YNLTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIP 544
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 285 bits (728), Expect = 2e-76
Identities = 191/573 (33%), Positives = 285/573 (49%), Gaps = 71/573 (12%)
Query: 46 PVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQ 105
PVV+T +GK+ G L PV +LG+P+A PP G RF PP+ W+ ++NAT
Sbjct: 25 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 83
Query: 106 FSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSK 165
+ +C Q LL ++ FT + + + +EDCLYLNIY P D+ ++N +
Sbjct: 84 YPPMCTQDPKAGQLLSEL----FTNRKENIPLKL---SEDCLYLNIYTPA--DLTKKN-R 133
Query: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLL 225
PVMV+IHGG M G + DG LA++ NV+V+TI RLGI GF STGD+ ++GN+G L
Sbjct: 134 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 193
Query: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 285
DQ+ ALRW+++N+ +FGG+P VTIFG AG VS+L LS ++ LF +AI +SG AL+
Sbjct: 194 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 253
Query: 286 SWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTI-----------TP 333
S V K +A GC + MV CL+ K +EL++ T+ P
Sbjct: 254 SVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDP 313
Query: 334 ATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE----------GLKFVDGI 383
G VIDG ++ P+ L + F M+G+N+ E +G
Sbjct: 314 RESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQ 373
Query: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443
+D + ++ + + L PE T K++ ++ ++ + L
Sbjct: 374 LDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL----GGTDDTVKKKDLFLDL 421
Query: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWADSAHGDEVPYVFGIPM 501
D + P+V A H G+PTY Y F + S+MKP HGDE+ VFG P
Sbjct: 422 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 481
Query: 502 IGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWS 560
+ S+ ++ LS +VM +W NFA+ G+PN + +P W
Sbjct: 482 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 519
Query: 561 KYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593
+YN K+ YL IG + + +VAFW L
Sbjct: 520 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 551
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 285 bits (728), Expect = 2e-76
Identities = 191/573 (33%), Positives = 285/573 (49%), Gaps = 71/573 (12%)
Query: 46 PVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQ 105
PVV+T +GK+ G L PV +LG+P+A PP G RF PP+ W+ ++NAT
Sbjct: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
Query: 106 FSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSK 165
+ +C Q LL ++ FT + + + +EDCLYLNIY P D+ ++N +
Sbjct: 83 YPPMCTQDPKAGQLLSEL----FTNRKENIPLKL---SEDCLYLNIYTPA--DLTKKN-R 132
Query: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLL 225
PVMV+IHGG M G + DG LA++ NV+V+TI RLGI GF STGD+ ++GN+G L
Sbjct: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
Query: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 285
DQ+ ALRW+++N+ +FGG+P VTIFG AG VS+L LS ++ LF +AI +SG AL+
Sbjct: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 252
Query: 286 SWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTI-----------TP 333
S V K +A GC + MV CL+ K +EL++ T+ P
Sbjct: 253 SVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDP 312
Query: 334 ATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE----------GLKFVDGI 383
G VIDG ++ P+ L + F M+G+N+ E +G
Sbjct: 313 RESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQ 372
Query: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443
+D + ++ + + L PE T K++ ++ ++ + L
Sbjct: 373 LDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL----GGTDDTVKKKDLFLDL 420
Query: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWADSAHGDEVPYVFGIPM 501
D + P+V A H G+PTY Y F + S+MKP HGDE+ VFG P
Sbjct: 421 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 480
Query: 502 IGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWS 560
+ S+ ++ LS +VM +W NFA+ G+PN + +P W
Sbjct: 481 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 518
Query: 561 KYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593
+YN K+ YL IG + + +VAFW L
Sbjct: 519 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 550
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 281 bits (719), Expect = 2e-75
Identities = 187/525 (35%), Positives = 264/525 (50%), Gaps = 69/525 (13%)
Query: 39 IDSQAQYPVVNTNYGKIQGLRTPLPSEILGP-VEQYLGVPYASPPTGERRFQPPESPSSW 97
+ S A+ V T G ++G+ L +LG V+ + G+P+A+P + + P+ W
Sbjct: 20 VASAAKLGAVYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFAAPT---KALENPQPHPGW 74
Query: 98 TGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQ---NEDCLYLNIYVP 154
G A F C Q T QD +EDCLYLNI+VP
Sbjct: 75 QGTLKAKNFKKRCLQ-----------------------ATITQDSTYGDEDCLYLNIWVP 111
Query: 155 MEDDIHEQNSKK-PVMVYIHGGSYMEGTGN--------MIDGSILASYGNVIVITINCRL 205
+Q S+ PVM++I+GG+++ G+G+ + DG +A+ GNVIV+T N R+
Sbjct: 112 QG---RKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRV 168
Query: 206 GILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTL 265
G LGFLSTGD GNYGL DQ A+ W++ N+ AFGGDP +T+FG AG + VSL TL
Sbjct: 169 GPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTL 228
Query: 266 SHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKN--- 322
S Y++GL ++AI QSG ALS W + P + + +A+KVGC + D M +CLK +
Sbjct: 229 SPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRA 288
Query: 323 ----YKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLK 378
YK + P +++ F PVIDGD IP DP L ++Y + G N +G
Sbjct: 289 LTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDY--IAGTNNMDGHI 346
Query: 379 F----VDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPE 434
F + I VT DF VS F +G + T WA + E
Sbjct: 347 FASIDMPAINKGNKKVTEEDFYKLVSEFT-----ITKGLRGAKTTFDVYTESWAQDPSQE 401
Query: 435 TRRKTLVALFTDHQWVAPA-VATADLHAQYGS-PTYFYAFYHHCQSEMKPSWADSAHGDE 492
++KT+V TD ++ P +A A A S TY Y F H + + P W + H D+
Sbjct: 402 NKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADD 461
Query: 493 VPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
+ YVFG P PT + D +S ++ YWTNFAKTGDPN
Sbjct: 462 IQYVFGKPFATPT-----GYRPQDRTVSKAMIAYWTNFAKTGDPN 501
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 280 bits (715), Expect = 5e-75
Identities = 187/596 (31%), Positives = 291/596 (48%), Gaps = 67/596 (11%)
Query: 19 VMLNSNVLLWITAL--AIKFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGV 76
V + S VL+ + L A T + P V+T G+++G + + V +LG+
Sbjct: 5 VRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDR-LVNVFLGI 63
Query: 77 PYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDE----RFLLHDMLPIWFTTSL 132
P+A PP G RF P W G+R+A+ +C Q ++ RF+L+ I+ +
Sbjct: 64 PFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVS-- 121
Query: 133 DTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILAS 192
EDCL LN+Y P E S +PVMV++HGG+ + G DGS LA+
Sbjct: 122 -----------EDCLVLNVYSPAEVPA---GSGRPVMVWVHGGALITGAATSYDGSALAA 167
Query: 193 YGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFG 252
YG+V+V+T+ RLG+LGF STGD+ A GN G LD + ALRW++EN+ FGGD VT+FG
Sbjct: 168 YGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFG 227
Query: 253 SGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTT 312
AG S +S L LS + GLF +AI QSG + ++ P + +A+ + C+
Sbjct: 228 GSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPA 287
Query: 313 DMVECLKNKNYKELI-----QQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDI 367
+MV+CL+ K +EL+ + TI P T +DG V P P+ L+++ F +
Sbjct: 288 EMVQCLQQKEGEELVLSKKLKNTIYPLT--------VDGTVFPKSPKELLKEKPFHSVPF 339
Query: 368 MLGVNQGEGLKFVD---GIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMY 424
++GVN E + G++D + ++ D + + +L PE T+ +
Sbjct: 340 LMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEY---- 395
Query: 425 TDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQS--EMKP 482
+ + + + D P V+ + GSP +FY F H S ++KP
Sbjct: 396 --LGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKP 453
Query: 483 SWADSAHGDEVPYVFGIP--MIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QP 539
+W + HG E +VFG P M + L ++ + LS +M WT+FA+TGDPN +
Sbjct: 454 AWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKA 513
Query: 540 VPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
+P W ++N +Q YL I PR +R + FW E +P
Sbjct: 514 LP----------------PWPQFNQAEQ-YLEINPVPRAGQKFREAWMQFWSETLP 552
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 274 bits (700), Expect = 3e-73
Identities = 182/573 (31%), Positives = 284/573 (49%), Gaps = 67/573 (11%)
Query: 31 ALAIKFTLIDSQAQ---YPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERR 87
A + L+ Q Q P+ T+ G++ G + G V+ +LG+P+A PP G R
Sbjct: 78 ACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLR 136
Query: 88 FQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQ-NEDC 146
F PPE P SW+G+R+ T A+C L D+ + MT+ D +EDC
Sbjct: 137 FAPPEPPESWSGVRDGTTHPAMC---------LQDLTAVESEFLSQFNMTFPSDSMSEDC 187
Query: 147 LYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLG 206
LYL+IY P + S PVMV+IHGG+ + G ++ DGS+LA+ NV+V+ I RLG
Sbjct: 188 LYLSIYTPAHS---HEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLG 244
Query: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266
+LGF STGD+ A GN+G LDQ+ ALRW+++N+ FGG+P RVTIFG AG + VS L +S
Sbjct: 245 VLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVS 304
Query: 267 HYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKEL 326
S+GLF AI++SG AL + + ++A+ C+ +D+ +V CL+ K+ +E+
Sbjct: 305 PISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEI 364
Query: 327 IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG---LKFVDGI 383
+ + + G V+DG +P PQ L+ +F ++GVN E + V I
Sbjct: 365 L---AINKPFKMIPG-VVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420
Query: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443
D + + ++ + L P D LRE D +P+T + +
Sbjct: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY------IGDNGDPQTLQAQFQEM 474
Query: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIG 503
D +V PA+ A +P YFY F H +PSW + +
Sbjct: 475 MADSMFVIPALQVAHFQCS-RAPVYFYEFQH------QPSWLKNIRPPHM---------- 517
Query: 504 PTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWSKY 562
+ F++ + LS +M YW NFA+ G+PN + +P W +
Sbjct: 518 --KADHVKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----------------WPLF 559
Query: 563 NPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
+ ++Q YL + L+P V +A ++ FW + +P
Sbjct: 560 DQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 591
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 237 bits (605), Expect = 3e-62
Identities = 178/572 (31%), Positives = 272/572 (47%), Gaps = 96/572 (16%)
Query: 27 LWITALAIKFTLIDSQAQYPVVNTNYGKIQGLR-TPLPSEILGPVEQYLGVPYASPPTGE 85
+W+ A K A+ P NT G IQG + T L S + PV +LGVP+A+PP G
Sbjct: 16 IWVLAAPTK----GPSAEGPQRNTRLGWIQGKQVTVLGSPV--PVNVFLGVPFAAPPLGS 69
Query: 86 RRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNED 145
RF P+ S W +R AT + +C Q+ + L ML + + +ED
Sbjct: 70 LRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKF---------GVSED 120
Query: 146 CLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRL 205
CLYLNIY P D SK PV+V+ GG++ G+ ++ DGS LA+Y +V+V+ + RL
Sbjct: 121 CLYLNIYAPAHADT---GSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177
Query: 206 GILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTL 265
GI GF +T DQ A GN+ DQ+ AL W+++N+ FGGDP VTIFG AGA VS L L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237
Query: 266 SHYSEGLFQKAIIQSGTALSSW--AVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNY 323
S ++GLF KAI++SG A+ + A +Y+ ++ +++A G N D+ ++ CL+ K
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPS 297
Query: 324 KELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI 383
KEL+ T++ T +F V+DG P++P L+ Q F ++GVN E F+ +
Sbjct: 298 KELL--TLSQKTK--SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE-CGFLLPM 352
Query: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443
+ + ++ ++ ++ + + N+ P L F DK + R +L+ L
Sbjct: 353 KEAPEILSGSNKSLAL-HLIQNILHIPPQYLHLVANEYF-----HDKHSLTEIRDSLLDL 406
Query: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIG 503
D +V PA+ TA H + G
Sbjct: 407 LGDVFFVVPALITARYHRE----------------------------------------G 426
Query: 504 PTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYN 563
TE + +LS +M YW FA+TG+PN + W YN
Sbjct: 427 ATE--------EEKLLSRKMMKYWATFARTGNPNGN---------------DLSLWPAYN 463
Query: 564 PKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
+Q YL + L + + +V FW +P
Sbjct: 464 LTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIP 494
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 227 bits (579), Expect = 3e-59
Identities = 140/369 (37%), Positives = 192/369 (52%), Gaps = 39/369 (10%)
Query: 28 WITALAIKFTLIDSQA------QYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASP 81
WI ++ L+ A + P V T YG +QG + + P++ +LGVP++ P
Sbjct: 3 WILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSRP 59
Query: 82 PTGERRFQPPESPSSWTGIRNATQFSAVCPQH----LDERFLLHDMLPIWFTTSLDTLMT 137
P G RF PPE P W GIR+AT + C Q L ++ W S
Sbjct: 60 PLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFS------ 113
Query: 138 YVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVI 197
EDCLYLN+Y P Q PVMV+ GG+++ G + +GS LA+ V+
Sbjct: 114 ------EDCLYLNVYAPARAPGDPQ---LPVMVWFPGGAFIVGAASSYEGSDLAAREKVV 164
Query: 198 VITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGA 257
++ + RLGI GFLST D A+GN+GLLDQ+ ALRW++EN+ AFGGDP VT+FG AGA
Sbjct: 165 LVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGA 224
Query: 258 SCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVEC 317
+S L +S + GLF +AI QSGTAL + P K + +A GCN T +V C
Sbjct: 225 MSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNC 284
Query: 318 LKN---------KNYKELIQQTI--TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYD 366
L+ N +Q P + PV+DG VIPDDP +L+ QG+ +
Sbjct: 285 LRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVP 344
Query: 367 IMLGVNQGE 375
+LGVN E
Sbjct: 345 YLLGVNNLE 353
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 16/75 (21%)
Query: 519 LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRV 578
LS +M YW NFA+TG+PN W +YN KD+ YL + RV
Sbjct: 421 LSLQMMKYWANFARTGNPNDG---------------NLPCWPRYN-KDEKYLQLDFTTRV 464
Query: 579 RDHYRATKVAFWLEL 593
+ K+AFW+ L
Sbjct: 465 GMKLKEKKMAFWMSL 479
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 189 bits (481), Expect = 7e-48
Identities = 141/481 (29%), Positives = 232/481 (48%), Gaps = 45/481 (9%)
Query: 70 VEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFT 129
V+Q+LGVPYA+PP ERRFQ PE P +WTG +A++ A C Q
Sbjct: 2225 VDQFLGVPYAAPPLAERRFQAPE-PLNWTGSWDASKPRASCWQP---------------- 2267
Query: 130 TSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNM--IDG 187
T + +EDCLYLN+++P V+V+ H E + IDG
Sbjct: 2268 ---GTRTSTSPGVSEDCLYLNVFIPQN-----VAPNASVLVFFHNTMDREESEGWPAIDG 2319
Query: 188 SILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 247
S LA+ GN+IV+T + R+G+ GFLS+G GN+GLLDQ+ AL W++ ++ FGGDP+R
Sbjct: 2320 SFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRR 2379
Query: 248 VTIFGSGAGASCVS--LLTLSHYSEGLFQKAIIQSGTALSSWAV-NYQPAKYTRI-LADK 303
V++ GA S LLT + LF++A++ G+ALS AV +++ A+ I LA +
Sbjct: 2380 VSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKE 2439
Query: 304 VGCNMLDTTDMVECLKNKNYKEL----IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQ 359
V C M + ++V CL+ K L + +H +GPVIDG + + P +++
Sbjct: 2440 VSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY-WGPVIDGHFLREPPARALKR 2498
Query: 360 GEFLNYDIMLGVNQGEGL-KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRE 418
++ D+++G +Q +GL + E+ + + N G + +
Sbjct: 2499 SLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEA 2558
Query: 419 TIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQS 478
+ Y+ ++ + + L D+ + P + A A+ F YH ++
Sbjct: 2559 AATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVF--MYHAPEN 2616
Query: 479 EMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQ 538
S A +V + G+P + FS + LS +M Y+++F ++G+PN
Sbjct: 2617 YGHGSLELLA---DVQFALGLPFY---PAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNY 2670
Query: 539 P 539
P
Sbjct: 2671 P 2671
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 150 bits (380), Expect = 4e-36
Identities = 82/204 (40%), Positives = 126/204 (61%), Gaps = 6/204 (2%)
Query: 174 GGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRW 233
GG++ G+ ++ DGS LA+Y +++V+ + RLGI GF +T DQ A GN+ DQ+ AL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 234 IEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSW--AVNY 291
+++N+ FGGDP VTIFG GA VS L LS +EGLF KA+++SG A+ + A +Y
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAIILYLKAHDY 139
Query: 292 QPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPD 351
+ ++ +++A G N D+ + CL+ K+ KEL+ T++ T AF V+DG P+
Sbjct: 140 EKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELL--TLSQKTK--AFTQVVDGAFFPN 195
Query: 352 DPQILMEQGEFLNYDIMLGVNQGE 375
+P L+ Q F ++GVN E
Sbjct: 196 EPLDLLSQKAFKAIPSIIGVNNPE 219
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 150 bits (380), Expect = 4e-36
Identities = 82/204 (40%), Positives = 126/204 (61%), Gaps = 6/204 (2%)
Query: 174 GGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRW 233
GG++ G+ ++ DGS LA+Y +++V+ + RLGI GF +T DQ A GN+ DQ+ AL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 234 IEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSW--AVNY 291
+++N+ FGGDP VTIFG GA VS L LS +EGLF KA+++SG A+ + A +Y
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAIILYLKAHDY 139
Query: 292 QPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPD 351
+ ++ +++A G N D+ + CL+ K+ KEL+ T++ T AF V+DG P+
Sbjct: 140 EKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELL--TLSQKTK--AFTQVVDGAFFPN 195
Query: 352 DPQILMEQGEFLNYDIMLGVNQGE 375
+P L+ Q F ++GVN E
Sbjct: 196 EPLDLLSQKAFKAIPSIIGVNNPE 219
>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 131
Score = 88.6 bits (218), Expect = 2e-17
Identities = 38/84 (45%), Positives = 59/84 (70%)
Query: 168 VMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQ 227
V+++ GG++ G+ ++ DGS LA+Y +++V+ + RLGI GF +T DQ A GN+ DQ
Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79
Query: 228 IQALRWIEENVGAFGGDPKRVTIF 251
+ AL W+++N+ FGGDP VTIF
Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIF 103
>gi|194394146 dipeptidylpeptidase 9 [Homo sapiens]
Length = 892
Score = 35.8 bits (81), Expect = 0.16
Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 20/150 (13%)
Query: 147 LYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDG------SILASYGNVIVIT 200
LY IY P + K P +++++GG ++ N G + LAS G +V+
Sbjct: 650 LYGMIYKP---HALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVI 706
Query: 201 I---NCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGA 257
+C+ G+ + +Q G + DQ++ L+++ E G D RV I G G
Sbjct: 707 DGRGSCQRGLRFEGALKNQ--MGQVEIEDQVEGLQFVAEKYGFI--DLSRVAIHGWSYG- 761
Query: 258 SCVSLLTLSHYSEGLFQKAIIQSGTALSSW 287
+SL+ L H + +F+ AI +G ++ W
Sbjct: 762 GFLSLMGLIHKPQ-VFKVAI--AGAPVTVW 788
>gi|11055976 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase
6 [Homo sapiens]
Length = 395
Score = 34.3 bits (77), Expect = 0.48
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 1/86 (1%)
Query: 559 WSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDM 618
W+ + LH+ ++ VR + F L P NL+++FQ+ + PP
Sbjct: 77 WTTLSQGSAATLHMAVRDLVRSVFLCDMDVFDAYL-PWRRNLSDLFQWAVSRALCSPPAC 135
Query: 619 TSFPYGTRRSPAKIWPTTKRPAITPA 644
++FP G S A P R + T A
Sbjct: 136 SAFPRGAISSEAVCKPLCARQSFTLA 161
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 32.0 bits (71), Expect = 2.4
Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 7/120 (5%)
Query: 610 TTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETK- 668
T K PP T +G R P + T A P+ S+ K T + E
Sbjct: 509 TEKEPPGPTTDGVWGGGRPGDAAGPASSS---TTAPAPRSSRPTEKAFTVPITDVTENAL 565
Query: 669 RDYSTELSVT-IAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTNDITHIQNE 727
+D + T I +G + + A + + K +++H+ H+H P R T +I ++++E
Sbjct: 566 KDLDDVMKTTKIIIGCFVAITFMAAVMLVAFYKLRKQHQLHKHHGPTR--TVEIINVEDE 623
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 31.6 bits (70), Expect = 3.1
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 3/60 (5%)
Query: 607 VSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKT---GPEDTTV 663
++TTT PP S P T SP TT P TP++ + P T P TT+
Sbjct: 1669 ITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTM 1728
Score = 30.8 bits (68), Expect = 5.3
Identities = 23/58 (39%), Positives = 25/58 (43%), Gaps = 4/58 (6%)
Query: 609 TTTKVPPPDMT-SFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKT---GPEDTT 662
TTT PPP T S P T SP I TT P TP+ + P T P TT
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1624
Score = 30.4 bits (67), Expect = 6.9
Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 4/71 (5%)
Query: 609 TTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHK---TGPEDTTVLI 665
TTT PPP T+ P T +P+ TT P IT P + P T P T +
Sbjct: 1638 TTTPSPPPTTTTTPPPT-TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTM 1696
Query: 666 ETKRDYSTELS 676
T +T S
Sbjct: 1697 TTPSPTTTPSS 1707
>gi|29029632 anaplastic lymphoma kinase [Homo sapiens]
Length = 1620
Score = 30.8 bits (68), Expect = 5.3
Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 8/49 (16%)
Query: 615 PPDMTSFPYGTRRSPAKIW-PT-----TKRPAITPANNPKHSKDPHKTG 657
PP +G+R P +W PT T++P T NNP K+PH G
Sbjct: 1485 PPSELHKVHGSRNKPTSLWNPTYGSWFTEKP--TKKNNPIAKKEPHDRG 1531
>gi|19923790 rab3 GTPase-activating protein, non-catalytic subunit
[Homo sapiens]
Length = 1393
Score = 30.8 bits (68), Expect = 5.3
Identities = 44/205 (21%), Positives = 82/205 (40%), Gaps = 17/205 (8%)
Query: 573 GLKPRVRDHYRATKVAFWLELVPHLHN-LNEIFQYVSTTTKVPPPDMTSFP--YGTRRSP 629
G+ R+ YR ++ W++ V LH + E + P + F Y RR
Sbjct: 416 GIAIRMWKGYRDAQIG-WIQTVEDLHERVPEKADFSPFGNSQGPSRVAQFLVIYAPRRGI 474
Query: 630 AKIWPTTKRPAITPANNPKHSK--DPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLF 687
++W T + P + N KH + P V ++ + + ++ + V S+
Sbjct: 475 LEVWSTQQGPRVGAFNVGKHCRLLYPGYKIMGLNNVTSQSWQPQTYQICLVDPVSGSVKT 534
Query: 688 LNILAFAALYYKKDKRRHETHRHPSPQRNTTNDITHIQNEEIMSLQMKQLEHD------- 740
+N+ AL KK +R + H ++ T N +++ ++K+L D
Sbjct: 535 VNVPFHLALSDKKSERAKDMH---LVKKLAALLKTKSPNLDLVETEIKELILDIKYPATK 591
Query: 741 -HECESLQAHDTLRLTCPPDYTLTL 764
ES+ A + L +C + T TL
Sbjct: 592 KQALESILASERLPFSCLRNITQTL 616
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 30.4 bits (67), Expect = 6.9
Identities = 17/52 (32%), Positives = 21/52 (40%)
Query: 609 TTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
TTTK P P T T + PA P P P K+P T P++
Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 332
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,448,882
Number of Sequences: 37866
Number of extensions: 1664717
Number of successful extensions: 4307
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3831
Number of HSP's gapped (non-prelim): 389
length of query: 816
length of database: 18,247,518
effective HSP length: 111
effective length of query: 705
effective length of database: 14,044,392
effective search space: 9901296360
effective search space used: 9901296360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.