Guide to the Human Genome
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Search of human proteins with 40288199

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo
sapiens]
         (552 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo sapiens]  1121   0.0  
gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]   757   0.0  
gi|124244056 family with sequence similarity 123B [Homo sapiens]      105   1e-22
gi|157427665 hypothetical protein LOC205147 [Homo sapiens]             84   3e-16
gi|157427663 hypothetical protein LOC205147 [Homo sapiens]             84   3e-16
gi|157427661 hypothetical protein LOC205147 [Homo sapiens]             84   3e-16
gi|157427667 hypothetical protein LOC205147 [Homo sapiens]             84   3e-16
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            49   2e-05
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       48   3e-05
gi|150170670 piccolo isoform 2 [Homo sapiens]                          46   8e-05
gi|150378539 piccolo isoform 1 [Homo sapiens]                          46   8e-05
gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]            46   1e-04
gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]            46   1e-04
gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]            46   1e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     46   1e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    45   1e-04
gi|59806361 hypothetical protein LOC387104 [Homo sapiens]              45   2e-04
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          44   4e-04
gi|84570137 homeobox B3 [Homo sapiens]                                 43   7e-04
gi|76056882 calcium binding protein 1 isoform 3 [Homo sapiens]         42   0.002
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]        41   0.002
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        41   0.002
gi|239756433 PREDICTED: hypothetical protein [Homo sapiens]            41   0.003
gi|239753184 PREDICTED: similar to hCG2040565 [Homo sapiens]           41   0.003
gi|239750970 PREDICTED: hypothetical protein XP_002347634 [Homo ...    41   0.003
gi|239747758 PREDICTED: hypothetical protein XP_002348261 [Homo ...    41   0.003
gi|239745376 PREDICTED: hypothetical protein XP_002343484 [Homo ...    41   0.003
gi|239741624 PREDICTED: hypothetical protein XP_002342251 [Homo ...    41   0.003
gi|55956910 meningioma  1 [Homo sapiens]                               40   0.004
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 40   0.006

>gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo sapiens]
          Length = 552

 Score = 1121 bits (2900), Expect = 0.0
 Identities = 552/552 (100%), Positives = 552/552 (100%)

Query: 1   METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS 60
           METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS
Sbjct: 1   METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS 60

Query: 61  GKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRK 120
           GKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRK
Sbjct: 61  GKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRK 120

Query: 121 EEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEP 180
           EEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEP
Sbjct: 121 EEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEP 180

Query: 181 VDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEE 240
           VDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEE
Sbjct: 181 VDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEE 240

Query: 241 TPRAAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQ 300
           TPRAAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQ
Sbjct: 241 TPRAAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQ 300

Query: 301 GGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCV 360
           GGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCV
Sbjct: 301 GGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCV 360

Query: 361 EAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSS 420
           EAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSS
Sbjct: 361 EAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSS 420

Query: 421 GKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTP 480
           GKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTP
Sbjct: 421 GKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTP 480

Query: 481 GSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVSNRGLAGTTI 540
           GSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVSNRGLAGTTI
Sbjct: 481 GSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVSNRGLAGTTI 540

Query: 541 RATACHDSAKKL 552
           RATACHDSAKKL
Sbjct: 541 RATACHDSAKKL 552


>gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]
          Length = 671

 Score =  757 bits (1954), Expect = 0.0
 Identities = 429/681 (62%), Positives = 453/681 (66%), Gaps = 139/681 (20%)

Query: 1   METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS 60
           METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS
Sbjct: 1   METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPS 60

Query: 61  GKINKAAFKLFKKRKSGGTMPSIFGVK--------------------------------- 87
           GKINKAAFKLFKKRKSGGTMPSIFGVK                                 
Sbjct: 61  GKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRK 120

Query: 88  -----------------NKGDGKSSGPTG--LVRS---RTHDGLAEVLVLESGRKEEPRG 125
                            N G  +++GP G  L  S   ++H   +  L+ ++GR E  +G
Sbjct: 121 EEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFS--LLKKNGRSENGKG 178

Query: 126 GGDSGGGGGGRPNPG--------------------PPRAAGPGGGSLASSSVAKSHSFFS 165
                   GG+   G                          PGGG +   S+  S     
Sbjct: 179 EPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTAS---LE 235

Query: 166 LLKKN--------------------GRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHR 205
            +K+                     G    G+  P  A +A  +  R   GL      H 
Sbjct: 236 CVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLA-----HP 290

Query: 206 KDKRAKAEAAEGRA---PGGGLILPGSLTASLECVKEETP----------RAAREPEEPS 252
            D  A+ E A G     PG G +      +    V  +T           RA   P+  S
Sbjct: 291 GDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPAS 350

Query: 253 QDAPRDPA---------------------GCGDIIADQEEEAGPSCDKHVPGPGKPALSK 291
            D P DP+                     GCGDIIADQEEEAGPSCDKHVPGPGKPALSK
Sbjct: 351 VDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSK 410

Query: 292 KNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVP 351
           KNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVP
Sbjct: 411 KNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVP 470

Query: 352 ETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTP 411
           ETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTP
Sbjct: 471 ETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTP 530

Query: 412 GPEEDSSSSGKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPG 471
           GPEEDSSSSGKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPG
Sbjct: 531 GPEEDSSSSGKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPG 590

Query: 472 TITCPLRTPGSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVS 531
           TITCPLRTPGSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVS
Sbjct: 591 TITCPLRTPGSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVS 650

Query: 532 NRGLAGTTIRATACHDSAKKL 552
           NRGLAGTTIRATACHDSAKKL
Sbjct: 651 NRGLAGTTIRATACHDSAKKL 671


>gi|124244056 family with sequence similarity 123B [Homo sapiens]
          Length = 1135

 Score =  105 bits (261), Expect = 1e-22
 Identities = 76/208 (36%), Positives = 109/208 (52%), Gaps = 24/208 (11%)

Query: 261 GCGDIIADQEEEAGPSCDKHVPGPGKPAL---SKKNPGVVAYQGGGEEMASPDEVDDTYL 317
           GCGDIIA+Q+ +   S    +   G+ A    +K++  +V YQGGGEEMA PD+ D+   
Sbjct: 327 GCGDIIAEQDMD---SMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEE 383

Query: 318 QEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPET----PKDTRCVEAAKDASSVKRRR 373
           +E    L + EE+  E +E         + + + ET    P+    +      S      
Sbjct: 384 EEEEVELEEEEEEVKEEEEDD-------DLEYLWETAQMYPRPNMNLGYHPTTSPGHHGY 436

Query: 374 LNRIPIEPHPKEEPKH---PEKEQQEGVPNSDEGYWDSTTPGPEEDSSSS---GKKAGIP 427
           +   P+  +P   P     P+ +QQE  PNSDEGY+DSTTPG E+DS  +    ++  +P
Sbjct: 437 MLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLVRRDCLP 496

Query: 428 RDSYSGDALYDLYADPDGSPATLPGGKD 455
           RDSYSGDALY+ Y +PD S    P G D
Sbjct: 497 RDSYSGDALYEFY-EPDDSLENSPPGDD 523


>gi|157427665 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 69/205 (33%), Positives = 96/205 (46%), Gaps = 38/205 (18%)

Query: 261 GCGDIIADQEEEAGPSCDKHVPGPGKPA-----LSKKNPGVVAYQGGGEEMASPDEVDDT 315
           GCG++ AD  E + PS + +  GP  P      L  K P     QG  E++ASP + + +
Sbjct: 249 GCGEVFAD--ESSVPSLELN-EGPESPTQAAQGLESKVPRG-PLQGSVEQLASPAQNEAS 304

Query: 316 YLQEFWDMLSQTEEQ------GP--EPQEGAAKVAAALETKVVPETPK-DTRCVEAAKDA 366
               FWD ++++  Q      GP     +G  +  + L+T  + E P    R   +   A
Sbjct: 305 DFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRSGSKA 364

Query: 367 SSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEED----SSSSGK 422
           SS+                +   P+ EQ E V  SDEGY+DS +PG EED     S    
Sbjct: 365 SSI----------------DTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTP 408

Query: 423 KAGIPRDSYSGDALYDLYADPDGSP 447
            A  PRDSYSGDALY+L+ DP   P
Sbjct: 409 AATFPRDSYSGDALYELFHDPSEGP 433


>gi|157427663 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 69/205 (33%), Positives = 96/205 (46%), Gaps = 38/205 (18%)

Query: 261 GCGDIIADQEEEAGPSCDKHVPGPGKPA-----LSKKNPGVVAYQGGGEEMASPDEVDDT 315
           GCG++ AD  E + PS + +  GP  P      L  K P     QG  E++ASP + + +
Sbjct: 249 GCGEVFAD--ESSVPSLELN-EGPESPTQAAQGLESKVPRG-PLQGSVEQLASPAQNEAS 304

Query: 316 YLQEFWDMLSQTEEQ------GP--EPQEGAAKVAAALETKVVPETPK-DTRCVEAAKDA 366
               FWD ++++  Q      GP     +G  +  + L+T  + E P    R   +   A
Sbjct: 305 DFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRSGSKA 364

Query: 367 SSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEED----SSSSGK 422
           SS+                +   P+ EQ E V  SDEGY+DS +PG EED     S    
Sbjct: 365 SSI----------------DTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTP 408

Query: 423 KAGIPRDSYSGDALYDLYADPDGSP 447
            A  PRDSYSGDALY+L+ DP   P
Sbjct: 409 AATFPRDSYSGDALYELFHDPSEGP 433


>gi|157427661 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 69/205 (33%), Positives = 96/205 (46%), Gaps = 38/205 (18%)

Query: 261 GCGDIIADQEEEAGPSCDKHVPGPGKPA-----LSKKNPGVVAYQGGGEEMASPDEVDDT 315
           GCG++ AD  E + PS + +  GP  P      L  K P     QG  E++ASP + + +
Sbjct: 249 GCGEVFAD--ESSVPSLELN-EGPESPTQAAQGLESKVPRG-PLQGSVEQLASPAQNEAS 304

Query: 316 YLQEFWDMLSQTEEQ------GP--EPQEGAAKVAAALETKVVPETPK-DTRCVEAAKDA 366
               FWD ++++  Q      GP     +G  +  + L+T  + E P    R   +   A
Sbjct: 305 DFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRSGSKA 364

Query: 367 SSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEED----SSSSGK 422
           SS+                +   P+ EQ E V  SDEGY+DS +PG EED     S    
Sbjct: 365 SSI----------------DTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTP 408

Query: 423 KAGIPRDSYSGDALYDLYADPDGSP 447
            A  PRDSYSGDALY+L+ DP   P
Sbjct: 409 AATFPRDSYSGDALYELFHDPSEGP 433


>gi|157427667 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 69/205 (33%), Positives = 96/205 (46%), Gaps = 38/205 (18%)

Query: 261 GCGDIIADQEEEAGPSCDKHVPGPGKPA-----LSKKNPGVVAYQGGGEEMASPDEVDDT 315
           GCG++ AD  E + PS + +  GP  P      L  K P     QG  E++ASP + + +
Sbjct: 249 GCGEVFAD--ESSVPSLELN-EGPESPTQAAQGLESKVPRG-PLQGSVEQLASPAQNEAS 304

Query: 316 YLQEFWDMLSQTEEQ------GP--EPQEGAAKVAAALETKVVPETPK-DTRCVEAAKDA 366
               FWD ++++  Q      GP     +G  +  + L+T  + E P    R   +   A
Sbjct: 305 DFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRSGSKA 364

Query: 367 SSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEED----SSSSGK 422
           SS+                +   P+ EQ E V  SDEGY+DS +PG EED     S    
Sbjct: 365 SSI----------------DTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTP 408

Query: 423 KAGIPRDSYSGDALYDLYADPDGSP 447
            A  PRDSYSGDALY+L+ DP   P
Sbjct: 409 AATFPRDSYSGDALYELFHDPSEGP 433


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 67/248 (27%), Positives = 91/248 (36%), Gaps = 49/248 (19%)

Query: 5   RSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPSGKIN 64
           +SRGGG     R G  A++   +R+  A AG                E PAA+   G+  
Sbjct: 265 KSRGGGDKKLRRQGQNAALAGAKRRGAATAG----------------EKPAAKGRGGRGP 308

Query: 65  KA----------AFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHD---GLAE 111
           K+            K  ++R    T  +  G K  G G+       V+SR      G   
Sbjct: 309 KSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKP 368

Query: 112 VLVLESGRKEEPRGGGDSGG------GGGGRPNP---GPPR------AAGPGGGSLASSS 156
                S    + RGGGD  G       G GR  P    P R      AA P GG    S 
Sbjct: 369 RRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGG---GSK 425

Query: 157 VAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAE 216
             +     +   + G+S +G G+         +QK    G  S  R  +K  R KA AA 
Sbjct: 426 KPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAES--RGDKKQGRQKASAAG 483

Query: 217 GRAPGGGL 224
            ++ GGGL
Sbjct: 484 TKSRGGGL 491



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 29/103 (28%), Positives = 39/103 (37%), Gaps = 1/103 (0%)

Query: 119 RKEEPRGGGDSGGGGGGRPNPGPPRAAGPGGG-SLASSSVAKSHSFFSLLKKNGRSENGK 177
           R ++PR G   GGGG      G  ++ G GG  S +    A S S      K  R    K
Sbjct: 714 RGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAK 773

Query: 178 GEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAP 220
               + +   G QK    G     R   +  R +  AA G+ P
Sbjct: 774 SRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKAAAGGKKP 816



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 46/184 (25%), Positives = 65/184 (35%), Gaps = 33/184 (17%)

Query: 73  KRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRG------- 125
           K + GG    +   K +GDG+        R R     A        +K   RG       
Sbjct: 379 KSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSR 438

Query: 126 GGDSGGGGGGRPN----PGPPRAAGPGG----------------GSLASSSVAKSHSFFS 165
           GG S  GGG +P         +AA  G                 G+ +     KSHS  +
Sbjct: 439 GGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKN 498

Query: 166 LLKKNGRSENG--KGEPVDASKAGGKQKR----GLRGLFSGMRWHRKDKRAKAEAAEGRA 219
           L ++  ++E    K     A   G KQ R     + G  S +   +  +R KA AA   +
Sbjct: 499 LWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATS 558

Query: 220 PGGG 223
            GGG
Sbjct: 559 HGGG 562



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 7/86 (8%)

Query: 118 GRKEEPRGGGDSGGGGGGRPNPGPPRAA----GPGGGSLASSSVAKSHSFFSLLKKNGR- 172
           G K    GG  S G GG +   G   AA    G GG        AKS S    +   G+ 
Sbjct: 728 GAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQK 787

Query: 173 --SENGKGEPVDASKAGGKQKRGLRG 196
             +  GK  P   S+ G  QK    G
Sbjct: 788 AAAAGGKKPPRVKSRGGRGQKAAAGG 813


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 59/217 (27%), Positives = 78/217 (35%), Gaps = 36/217 (16%)

Query: 268 DQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQT 327
           D  E   P CD  VP    P     NP     +G GE         +TY  E+       
Sbjct: 235 DYCEHYSPDCDTAVPDT--PQSQDPNPDEYYTEGDGE--------GETYYYEY-PYYEDP 283

Query: 328 EEQGPEPQEGAAKVAAALETKVVPE--TPKDTRCV------EAAKDASSVKRRRLNRIPI 379
           E+ G EP      V AA ET  VPE  TP  T         E A     V     + +P 
Sbjct: 284 EDLGKEPTPSKKPVEAAKETTEVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPS 343

Query: 380 E----PHPKEEPKHPEKEQQEGVP-NSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSG- 433
           E    P P ++  + E E+    P +   G    T+     +SS+     G   D   G 
Sbjct: 344 EDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGE 403

Query: 434 ----------DALYDLYADPDGSPATL-PGGKDNEET 459
                     +  YD Y DP  SP+ + PG   N++T
Sbjct: 404 FTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDT 440



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 67/306 (21%), Positives = 95/306 (31%), Gaps = 28/306 (9%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVD 182
            P   G++G  G   P PGPP   GP G   A                N  +   KGEP +
Sbjct: 1236 PGEKGETGDVGQMGP-PGPPGPRGPSGAPGADGPQGPPGGI-----GNPGAVGEKGEPGE 1289

Query: 183  ASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETP 242
            A + G   + G  G           K  + E  E   P G    PG      +   + +P
Sbjct: 1290 AGEPGLPGEGGPPG----------PKGERGEKGES-GPSGAAGPPGPKGPPGDDGPKGSP 1338

Query: 243  RAAREPEEPSQDAPRDPAG----CGDIIADQEE-EAGPSCDKHVPGPGKPALSKKNPGVV 297
                 P +P       PAG     GD   D E  + G       PGP  P   +  PG  
Sbjct: 1339 GPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPA 1398

Query: 298  AYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDT 357
              +G   E  +  E            +      G    +G   +   +  + +P +P   
Sbjct: 1399 GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPD 1458

Query: 358  RCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDS 417
                       +    L  +  +  PK E  HP      G P       D   PGP+  S
Sbjct: 1459 ------GPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSS 1512

Query: 418  SSSGKK 423
               G++
Sbjct: 1513 GPKGEQ 1518



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 77/357 (21%), Positives = 104/357 (29%), Gaps = 68/357 (19%)

Query: 88   NKGDGKSSGPTGLVRSRTHDGLAEVLVLES--GRKEEPRGGGDSGGGGGGRPN------- 138
            N+G     GP G    R   G A  + +    G +  P   G+ G  G   P        
Sbjct: 1076 NEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135

Query: 139  -------PGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGK-------GEPVDAS 184
                   PGP    GP G       + +     S   K  +   G        G+P  + 
Sbjct: 1136 LQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG 1195

Query: 185  KAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRA 244
              G    RG +GLF      +K             P G   LPG             P  
Sbjct: 1196 ADGEPGPRGQQGLFG-----QKGDEGPRGFPGPPGPVGLQGLPGP------------PGE 1238

Query: 245  AREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGGE 304
              E  +  Q  P  P G            GPS      GP  P     NPG V  +G   
Sbjct: 1239 KGETGDVGQMGPPGPPG----------PRGPSGAPGADGPQGPPGGIGNPGAVGEKG--- 1285

Query: 305  EMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCVEAAK 364
                P E  +  L           E+G + + G +  A        P  PK     +  K
Sbjct: 1286 ---EPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAG-------PPGPKGPPGDDGPK 1335

Query: 365  DASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSG 421
             +           P +P P  EP    ++   G    D     + +PGP  +   SG
Sbjct: 1336 GSPGPVG-----FPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSG 1387



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 59/232 (25%), Positives = 78/232 (33%), Gaps = 39/232 (16%)

Query: 89   KGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGG--GRPN-------- 138
            KGD    GP G    R  DG            E P+G G   G  G  G P         
Sbjct: 825  KGDRGEIGPPG---PRGEDG-----------PEGPKGRGGPNGDPGPLGPPGEKGKLGVP 870

Query: 139  --PGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPV-DASKAGGKQKRGLR 195
              PG P   GP G S+       ++      +K GR   GK  P       G + +RG R
Sbjct: 871  GLPGYPGRQGPKG-SIGFPGFPGANG-----EKGGRGTPGKPGPRGQRGPTGPRGERGPR 924

Query: 196  GLFS--GMRWHRK-DKRAKAEAAEG-RAPGGGLILPGSLTASLECVKEETPRAAREPEEP 251
            G+    G + +   D  A      G   P G    PG         K+  P    +  E 
Sbjct: 925  GITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984

Query: 252  SQDAPRDPAGCGDIIADQEE--EAGPSCDKHVPGPGKPALSKKNPGVVAYQG 301
                   P G   ++  Q    E GP  ++  PGP  P   +  PG+   +G
Sbjct: 985  GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEG 1036


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 91/422 (21%), Positives = 145/422 (34%), Gaps = 31/422 (7%)

Query: 153 ASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKA 212
           A SSV    + F L+     SE  + E     K   K++    G+       +  K    
Sbjct: 165 AVSSVVNKFNPFDLISD---SEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPK 221

Query: 213 EAAEGRAPGGGLILPGSLTASL-ECVKEETPRAAREPEEPSQDAPRDPAGCG---DIIAD 268
           +   GR P      P S+++   E +K + P   +  + P+Q    D A      D    
Sbjct: 222 QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281

Query: 269 QEEEA----GPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDML 324
           Q ++A    G S    +P P KP + +  PG    Q  G E + P              L
Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG---L 338

Query: 325 SQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCVEAAKDASSVKR---RRLNRIP-IE 380
           ++   Q P   +   +     +    P  P      +   +  S ++   + L + P + 
Sbjct: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398

Query: 381 PHPKEEPKHPEKE--QQEGVPN---SDEGYWD-STTPGPEEDSSSSGKKAGIPRDSYSGD 434
             P ++P  P K   QQ G P       G    +  PGP +          IP       
Sbjct: 399 KTPAQQPG-PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457

Query: 435 ALYDLYADPDGSPATLPG-GKDNEETSSLSRLKPVSPGTITCPLRTPGSLLKDSKIPISI 493
                   P   P+ LPG  K   +    ++  P  PG+   P + PGS     + P   
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA 517

Query: 494 KHLTNLPSSHPVVHQQPS----RSEMPRTKIPVSKVLVRRVSNRGLAGTTIRATACHDSA 549
           K     P S     QQP      ++ P    P ++   + VS  G +G  ++      SA
Sbjct: 518 KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-SGKPLQPPTVSPSA 576

Query: 550 KK 551
           K+
Sbjct: 577 KQ 578



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 32/188 (17%), Positives = 70/188 (37%), Gaps = 10/188 (5%)

Query: 244 AAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGG 303
           +A+  + P  D+   PA   +     E++  P  D     P +P + K    +V+     
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK---PKQPKMVKPTTDLVSSSSAT 773

Query: 304 EEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQ-EGAAKVAAALETKVVPETPKDTRCVEA 362
            +   P     +  +E      +T+   P        +  +  ++K +P    D++ +  
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISH 833

Query: 363 AKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGK 422
              +S  K ++      +  P ++ + P+K Q +  P  D       +P P     ++G+
Sbjct: 834 PGPSSESKGQK------QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887

Query: 423 KAGIPRDS 430
               P+ S
Sbjct: 888 TVPTPQQS 895



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 28/218 (12%)

Query: 284  PGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAA 343
            P  P+  K +P  V  +   ++ A P +V     QE      + + +  +      K   
Sbjct: 1126 PPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQE-----QEVKTEAEKVILEKVKETL 1180

Query: 344  ALETKVVPETPKDTRCVEAA--KDASSVKRRRL------NRIPIEPHPKEEPKHPEKEQQ 395
            ++E K+ P    D +  E+   KD +S  + +         IP E   + E K P  E++
Sbjct: 1181 SME-KIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK 1239

Query: 396  EGVPNSDEGYWDSTTPGPEEDSSSSGK-KAGIPRDSYSGDALYDLYAD-----------P 443
            +  P   +   ++ T  PEE      K +  I  +   G        +           P
Sbjct: 1240 KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP 1299

Query: 444  DGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTPG 481
             G+P +LP  K++++T+   + +P  P T       PG
Sbjct: 1300 SGTPQSLP--KEDDKTTKTIKEQPQPPCTAKPDQVEPG 1335


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 91/422 (21%), Positives = 145/422 (34%), Gaps = 31/422 (7%)

Query: 153 ASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKA 212
           A SSV    + F L+     SE  + E     K   K++    G+       +  K    
Sbjct: 165 AVSSVVNKFNPFDLISD---SEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPK 221

Query: 213 EAAEGRAPGGGLILPGSLTASL-ECVKEETPRAAREPEEPSQDAPRDPAGCG---DIIAD 268
           +   GR P      P S+++   E +K + P   +  + P+Q    D A      D    
Sbjct: 222 QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281

Query: 269 QEEEA----GPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDML 324
           Q ++A    G S    +P P KP + +  PG    Q  G E + P              L
Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG---L 338

Query: 325 SQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCVEAAKDASSVKR---RRLNRIP-IE 380
           ++   Q P   +   +     +    P  P      +   +  S ++   + L + P + 
Sbjct: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398

Query: 381 PHPKEEPKHPEKE--QQEGVPN---SDEGYWD-STTPGPEEDSSSSGKKAGIPRDSYSGD 434
             P ++P  P K   QQ G P       G    +  PGP +          IP       
Sbjct: 399 KTPAQQPG-PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457

Query: 435 ALYDLYADPDGSPATLPG-GKDNEETSSLSRLKPVSPGTITCPLRTPGSLLKDSKIPISI 493
                   P   P+ LPG  K   +    ++  P  PG+   P + PGS     + P   
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA 517

Query: 494 KHLTNLPSSHPVVHQQPS----RSEMPRTKIPVSKVLVRRVSNRGLAGTTIRATACHDSA 549
           K     P S     QQP      ++ P    P ++   + VS  G +G  ++      SA
Sbjct: 518 KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-SGKPLQPPTVSPSA 576

Query: 550 KK 551
           K+
Sbjct: 577 KQ 578



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 32/188 (17%), Positives = 70/188 (37%), Gaps = 10/188 (5%)

Query: 244 AAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGG 303
           +A+  + P  D+   PA   +     E++  P  D     P +P + K    +V+     
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK---PKQPKMVKPTTDLVSSSSAT 773

Query: 304 EEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQ-EGAAKVAAALETKVVPETPKDTRCVEA 362
            +   P     +  +E      +T+   P        +  +  ++K +P    D++ +  
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISH 833

Query: 363 AKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGK 422
              +S  K ++      +  P ++ + P+K Q +  P  D       +P P     ++G+
Sbjct: 834 PGPSSESKGQK------QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887

Query: 423 KAGIPRDS 430
               P+ S
Sbjct: 888 TVPTPQQS 895



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 28/218 (12%)

Query: 284  PGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAA 343
            P  P+  K +P  V  +   ++ A P +V     QE      + + +  +      K   
Sbjct: 1126 PPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQE-----QEVKTEAEKVILEKVKETL 1180

Query: 344  ALETKVVPETPKDTRCVEAA--KDASSVKRRRL------NRIPIEPHPKEEPKHPEKEQQ 395
            ++E K+ P    D +  E+   KD +S  + +         IP E   + E K P  E++
Sbjct: 1181 SME-KIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK 1239

Query: 396  EGVPNSDEGYWDSTTPGPEEDSSSSGK-KAGIPRDSYSGDALYDLYAD-----------P 443
            +  P   +   ++ T  PEE      K +  I  +   G        +           P
Sbjct: 1240 KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP 1299

Query: 444  DGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTPG 481
             G+P +LP  K++++T+   + +P  P T       PG
Sbjct: 1300 SGTPQSLP--KEDDKTTKTIKEQPQPPCTAKPDQVEPG 1335


>gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 48/172 (27%), Positives = 62/172 (36%), Gaps = 28/172 (16%)

Query: 73  KRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEP--RGGGDSG 130
           KR+  G  P     +  G G   G     R     G   + V + G       RGGG   
Sbjct: 146 KRRGWGLRPQRVRSRLAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGGS 205

Query: 131 GGGGGRPNPGPPRAAGPGGGSLASSSV-----AKSHSFFSLLKKNGR----------SEN 175
            GGGG   P PPRA  P  G            A+ H+  + L ++G+          S  
Sbjct: 206 EGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSR 265

Query: 176 GKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGR-----APGG 222
           G+G     S A    + G RG        R D RA+   A+ R     APGG
Sbjct: 266 GRGAATSVSAAARPTRGGARG------HRRADGRARGGCAQLRAGTPSAPGG 311


>gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 48/172 (27%), Positives = 62/172 (36%), Gaps = 28/172 (16%)

Query: 73  KRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEP--RGGGDSG 130
           KR+  G  P     +  G G   G     R     G   + V + G       RGGG   
Sbjct: 146 KRRGWGLRPQRVRSRLAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGGS 205

Query: 131 GGGGGRPNPGPPRAAGPGGGSLASSSV-----AKSHSFFSLLKKNGR----------SEN 175
            GGGG   P PPRA  P  G            A+ H+  + L ++G+          S  
Sbjct: 206 EGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSR 265

Query: 176 GKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGR-----APGG 222
           G+G     S A    + G RG        R D RA+   A+ R     APGG
Sbjct: 266 GRGAATSVSAAARPTRGGARG------HRRADGRARGGCAQLRAGTPSAPGG 311


>gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 48/172 (27%), Positives = 62/172 (36%), Gaps = 28/172 (16%)

Query: 73  KRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEP--RGGGDSG 130
           KR+  G  P     +  G G   G     R     G   + V + G       RGGG   
Sbjct: 146 KRRGWGLRPQRVRSRLAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGGS 205

Query: 131 GGGGGRPNPGPPRAAGPGGGSLASSSV-----AKSHSFFSLLKKNGR----------SEN 175
            GGGG   P PPRA  P  G            A+ H+  + L ++G+          S  
Sbjct: 206 EGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSR 265

Query: 176 GKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGR-----APGG 222
           G+G     S A    + G RG        R D RA+   A+ R     APGG
Sbjct: 266 GRGAATSVSAAARPTRGGARG------HRRADGRARGGCAQLRAGTPSAPGG 311


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 89/413 (21%), Positives = 142/413 (34%), Gaps = 66/413 (15%)

Query: 93  KSSGPTGLVRSRTHDGLAEVLVLESGRKE-------EPRGGGDSGGGGGGRPNPGPPRAA 145
           KS   T +V  +T +      V E   KE       E  GG +    GG      PP   
Sbjct: 449 KSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEE 508

Query: 146 GPGGGSLASSSV---AKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMR 202
                  A S V   AKS +     +K       + +  + +K+  K++       S   
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK-----SPPE 563

Query: 203 WHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEE--TPRAAREPEE---PSQDAPR 257
               +K      AE ++P            +    KEE  +P  A+ PE+   P ++  +
Sbjct: 564 AKSPEKEEAKSPAEVKSP----------EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613

Query: 258 DPAGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYL 317
            PA     +  +EE   P+    V  P K     K           EE  SP++      
Sbjct: 614 SPAEAKSPV--KEEAKSPA---EVKSPEKAKSPTK-----------EEAKSPEKAK---- 653

Query: 318 QEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCVEAAKDASSVKRRRLNRI 377
                  S  +E+   P++  + V A  ++    ++P         K  S VK    +  
Sbjct: 654 -------SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE 706

Query: 378 PIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSGDALY 437
             +   KEE K PEK +    P  +E         P ++ + S +KA  P  + + D   
Sbjct: 707 KAKSPVKEEAKSPEKAKS---PVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 763

Query: 438 DLYADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTPGSLLKDSKIP 490
                P    A  P  K  E+  S  + +  SP     PL+      +D+K P
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK------EDAKAP 810



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 41/179 (22%), Positives = 71/179 (39%), Gaps = 10/179 (5%)

Query: 340 KVAAALETKVVPETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVP 399
           KV +  + KVV ++ K+T  VE   + + V          E   KE  +   KE++ G  
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEE-----VTEEEEKEAKEEEGKEEEGGEE 491

Query: 400 NSDEGYWDSTTPGPEEDSSSSGKKAGIP--RDSYSGDALYDLYADPDGSPATLPGGKDNE 457
              EG  + T   P E+++S  K+A  P   ++ S         +   SPA +   K  E
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV---KSPE 548

Query: 458 ETSSLSRLKPVSPGTITCPLRTPGSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMP 516
           +  S ++ +  SP     P +       + K P   K      +  P   + P +++ P
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607



 Score = 29.6 bits (65), Expect = 7.5
 Identities = 56/259 (21%), Positives = 93/259 (35%), Gaps = 37/259 (14%)

Query: 237 VKEE--TPRAAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNP 294
           VKEE  +P  A+ PE+      + P    +     +EEA    DK       P   +   
Sbjct: 740 VKEEAKSPEKAKSPEKAKTLDVKSP----EAKTPAKEEARSPADKFPEKAKSPVKEEVKS 795

Query: 295 GVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAA-LETKVVPET 353
              A     E+  +P++     + +  ++ S  +E+  +PQE   K      E +  P T
Sbjct: 796 PEKAKSPLKEDAKAPEKE----IPKKEEVKSPVKEE-EKPQEVKVKEPPKKAEEEKAPAT 850

Query: 354 PK-----DTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEG---VP------ 399
           PK     D++  EA K  +   +    + P    PKE     +KE+ E    VP      
Sbjct: 851 PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEA 910

Query: 400 ------NSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSG-----DALYDLYADPDGSPA 448
                   D    + T    +E   +  K+   P +         D   +    P+  P 
Sbjct: 911 PAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPK 970

Query: 449 TLPGGKDNEETSSLSRLKP 467
           T    K++++T S    KP
Sbjct: 971 TEAKAKEDDKTLSKEPSKP 989


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 67/334 (20%), Positives = 120/334 (35%), Gaps = 39/334 (11%)

Query: 168 KKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILP 227
           KK+ + + G+ E  +  K  G  K  ++ +   +   ++++  +    E R         
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERI-------- 366

Query: 228 GSLTASLECVKEETPRAAREPEEPSQDAPRDPAGC----GDIIADQEEEAGPSCD----- 278
                 LE  ++E  R  +E  E  +   ++        G ++   + EA    +     
Sbjct: 367 -KRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKL 425

Query: 279 ---KHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTE--EQGP- 332
              + V  P K +L KK P    Y+    +   P +++   + E  ++ +  E  EQG  
Sbjct: 426 LQAQGVEVPSKDSLPKKRP---IYEDKKRKKI-PQQLESKEVSESMELCAAVEVMEQGVP 481

Query: 333 ---------EPQEGAAKVAAALETKVVPETPKDTRCVEAAKDASSVKRRRLNRIPIEPHP 383
                    EP+E      A L+      + ++T  VE  K    VK         E   
Sbjct: 482 EKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEE 541

Query: 384 KEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSGDALYDLYADP 443
           +E+ +  E+E++EG     EG  +      E+DS  +  K   P    S D+ YD   D 
Sbjct: 542 EEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKK--PSKEMSSDSEYDSDDDR 599

Query: 444 DGSPATLPGGKDNEETSSLSRLKPVSPGTITCPL 477
                     K   E   L   K V+   +  P+
Sbjct: 600 TKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPI 633



 Score = 29.6 bits (65), Expect = 7.5
 Identities = 28/135 (20%), Positives = 54/135 (40%), Gaps = 4/135 (2%)

Query: 300 QGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRC 359
           Q    E ++ D++D   L    +     +EQ P+  +G  K     +     +  K+   
Sbjct: 5   QKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELE- 63

Query: 360 VEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSS 419
            E + +A  +K  R   + ++P    E +   K++++      +  +D       ED  S
Sbjct: 64  -ELSLEAQGIKADR-ETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDS 121

Query: 420 SGKKAGIPR-DSYSG 433
             KK   P+ + YSG
Sbjct: 122 KSKKTAKPKVEMYSG 136


>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
          Length = 947

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 49/174 (28%), Positives = 62/174 (35%), Gaps = 22/174 (12%)

Query: 125 GGGDSGGGG---GGRPNPGPPRA----------AGPGGGSLASSSVAKSHSFFSLLKKNG 171
           GGG  GG G   GG P P PPR            G  GG  AS S + S    S  K  G
Sbjct: 173 GGGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSS----SAGKTPG 228

Query: 172 RSENGKGEPVDASKAGGKQKRGLRGLFSG--MRWHRKDKRAKAEAAEGR---APGGGLIL 226
                 G  V    +GG       G      +++H K +RA A AA  +     GGG   
Sbjct: 229 TGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNGGGSSS 288

Query: 227 PGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKH 280
             S  +    V E    A+  P   + + P+  A         +  A PS   H
Sbjct: 289 RSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPH 342



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 58/256 (22%), Positives = 81/256 (31%), Gaps = 76/256 (29%)

Query: 9   GGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPSGKINKAAF 68
           GGG   E GGAG   G    + E GA                   P   PP G   K   
Sbjct: 166 GGGGGGEGGGAGGGSG----EREGGA-------------------PQPPPPRGWRGKGV- 201

Query: 69  KLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGD 128
              + ++ GG         + G+G S  P+     +T            G      G G 
Sbjct: 202 ---RAQQRGG---------SGGEGASPSPSSSSAGKT-----------PGTGSRNSGSGV 238

Query: 129 SGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGG 188
           +GGG G             GGGS       +S      LKK   +       + A   GG
Sbjct: 239 AGGGSG-------------GGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNGGG 285

Query: 189 KQKR-----GLRGLFSGMRWHRKDKRAKA-----EAAEGRAPGGGLILPGSLTASLECVK 238
              R     G   +   +        A A     ++AEG A GGG      + A+     
Sbjct: 286 SSSRSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGG------MQAAAPPSS 339

Query: 239 EETPRAAREPEEPSQD 254
           +  P+  +E EE  ++
Sbjct: 340 QPHPQQLQEQEEMQEE 355


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 93/345 (26%), Positives = 119/345 (34%), Gaps = 82/345 (23%)

Query: 7    RGGGGAVSERGGAG--ASVGVCRRKAEAG----AGTGTLAADMDLHCDCAAETPAAEPPS 60
            RG  GA+  +G  G    +G    K E G    AG+  L           A  P A+ P 
Sbjct: 1470 RGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPG--------VAGRPGAKGPE 1521

Query: 61   GKINKAAFKLFKKRKSGGTMPSIFGVK------NKGDGKSSGP---TGLVRSRTHDGLAE 111
            G       +  K        P++ G         KGD   +GP   TG+   R   GL  
Sbjct: 1522 GPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGL-- 1579

Query: 112  VLVLESGRKEEP----------RGG--GDSGGGG--GGRPNPGPPRAAGPGGGSLASSSV 157
            VL  + G K +P          R G  GDSG  G  G    PGPP   GP G        
Sbjct: 1580 VLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRG-------- 1631

Query: 158  AKSHSFFSLLKKNGR--SENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAA 215
                       ++G    +  +G P D    G   +RGLRG   G+R    +K  + +  
Sbjct: 1632 -----------RDGEVGEKGDEGPPGDPGLPGKAGERGLRGA-PGVRGPVGEKGDQGDPG 1679

Query: 216  E-GR-------APGGGLILPGSLTASLECVKEETPRAAREPEEP---SQDAPRDPAGCGD 264
            E GR        P G    PG        V  +T   ARE  EP    Q+ PR P G   
Sbjct: 1680 EDGRNGSPGSSGPKGDRGEPGPPGPPGRLV--DTGPGAREKGEPGDRGQEGPRGPKGDPG 1737

Query: 265  IIADQEEEA--------GPSCDKHVPGPGKPALSKKNPGVVAYQG 301
            +     E          GP  D  V GP      +  PG+    G
Sbjct: 1738 LPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSG 1782



 Score = 36.2 bits (82), Expect = 0.080
 Identities = 54/190 (28%), Positives = 69/190 (36%), Gaps = 19/190 (10%)

Query: 118  GRKEEPRGGGDSG--GGGGGRPNPG-PPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSE 174
            G+K EP   G+ G  G  G   +PG P R   PG      S+ AK    F        S 
Sbjct: 1254 GQKGEP---GEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSP 1310

Query: 175  NGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAE-AAEGRAPGG-GLILPGSLTA 232
               G P      G K   GL G   G    R  +  K E  A G+  GG G  LPG    
Sbjct: 1311 GRAGNPGTPGAPGLKGSPGLPGP-RGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGR--- 1366

Query: 233  SLECVKEETPRAAREPEEPSQD-APRDPAGCGDIIADQEEEAGPSCDKHVPGPGKPALSK 291
                  +  P     P  P  D  PR P G        + + G   ++  PGPG+  ++ 
Sbjct: 1367 ----KGDPGPSGPPGPRGPLGDPGPRGPPGLPG--TAMKGDKGDRGERGPPGPGEGGIAP 1420

Query: 292  KNPGVVAYQG 301
              PG+    G
Sbjct: 1421 GEPGLPGLPG 1430



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 63/227 (27%), Positives = 77/227 (33%), Gaps = 35/227 (15%)

Query: 77   GGTMPSIFGVKNKGDGKSSGPTGL------VRSRTHDGLAEVLVL-ESGRKEE--PRGGG 127
            GG  P + G   KGD   SGP G          R   GL    +  + G + E  P G G
Sbjct: 1357 GGEGPGLPG--RKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPG 1414

Query: 128  DSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENG-KGEPVDASKA 186
            + G   G    PG P + GP G                   + G SE+G  G P      
Sbjct: 1415 EGGIAPGEPGLPGLPGSPGPQGPVGPPGKKG----------EKGDSEDGAPGLPGQPGSP 1464

Query: 187  GGKQKRGLRGLFSGMRWHRKDKRAKAEAAE-----GRAPGGGLILPGSLTASLECVKEET 241
            G +  RG  G   G +  R       EA E        P G   LPG          E  
Sbjct: 1465 GEQGPRGPPGAI-GPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGP 1523

Query: 242  P-RAAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKP 287
            P    R+ E+     P DPA  G  +      AGP  +K   GP  P
Sbjct: 1524 PGPTGRQGEKGEPGRPGDPAVVGPAV------AGPKGEKGDVGPAGP 1564


>gi|84570137 homeobox B3 [Homo sapiens]
          Length = 431

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 60/223 (26%), Positives = 82/223 (36%), Gaps = 21/223 (9%)

Query: 51  AETPAAEPPSGKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGL- 109
           A  P + PP      AA        S G  PS  G    G G +S  T  +     +   
Sbjct: 79  APEPLSAPPGSPPPSAAPTSATSNSSNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQ 138

Query: 110 AEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRAAGPGG-----GSLASSSVAKSHSFF 164
              L   S    E  GGG  GGGGGG    G     G GG     GS AS     +++  
Sbjct: 139 TSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSA 198

Query: 165 SL--LKKNGRSENGKGEP--VDASKAGGKQKRGLRGLFSGMRW-HRKDKRAK--AEAAEG 217
            L  L+K          P  V+ +      +R ++  F   R  ++KD++AK  A ++ G
Sbjct: 199 QLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGG 258

Query: 218 RAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPA 260
            +P G    P   TA            A     PS ++P  PA
Sbjct: 259 PSPAGSPPQPMQSTAGF--------MNALHSMTPSYESPSPPA 293


>gi|76056882 calcium binding protein 1 isoform 3 [Homo sapiens]
          Length = 370

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 72/252 (28%), Positives = 97/252 (38%), Gaps = 39/252 (15%)

Query: 96  GPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASS 155
           G  G    R  DG     VL  G + EPR    +GG    R  P PP  A  G  ++ SS
Sbjct: 3   GGDGAAFKRPGDGARLQRVLGLGSRREPRSL-PAGGPAPRRTAPPPPGHASAGPAAM-SS 60

Query: 156 SVAKSHSFFSLLKKNGRSENG--KGEPVDASKAGGKQKRGLRG------LFSGMRWHRKD 207
            +AKS S  SLLK    + +G  +      ++  G   R L G        SG    R+ 
Sbjct: 61  HIAKSESKTSLLKAAAAAASGGSRAPRHGPARDPGLPSRRLPGSCPATPQSSGDPSSRRP 120

Query: 208 KRAKAEAAEGRAPGGGLILPGSLTASLEC-VKEETPRAAREPEEPSQDAPRDPAGCGDII 266
               A   EG A G   +LP        C  +E  P AA     PS  +P  PA   D  
Sbjct: 121 LCRPAPREEG-ARGSQRVLP-----QAHCRPREALPAAA---SRPSPSSPLPPARGRD-- 169

Query: 267 ADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQ 326
               EE G S          PAL  +  G +  +G G+ + +     D +L     MLS 
Sbjct: 170 ---GEERGLS----------PALGLR--GSLRARGRGDSVPAAASEADPFLHRLRPMLSS 214

Query: 327 T--EEQGPEPQE 336
              +++   P+E
Sbjct: 215 AFGQDRSLRPEE 226


>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
          Length = 380

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/102 (29%), Positives = 41/102 (40%), Gaps = 11/102 (10%)

Query: 130 GGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGK 189
           G GGG  P P  P A GPGGG   +  +A + +   L K + + E   G     +++G  
Sbjct: 199 GAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRS 258

Query: 190 QKRGLRGLFSGMRWHR-----------KDKRAKAEAAEGRAP 220
              GL    + M   R           KD+ A  E  E R P
Sbjct: 259 GGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVP 300



 Score = 33.1 bits (74), Expect = 0.68
 Identities = 38/150 (25%), Positives = 55/150 (36%), Gaps = 30/150 (20%)

Query: 119 RKEEPRGGGDSGGGGGGRPNPGPPRAAG--PGGGSLASSSVAKSHSFFSLLKKNGRSENG 176
           R+    GG  +   GG  P PGPP   G  P  G   S   A +H              G
Sbjct: 154 RRVSNAGGPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVPAAAHG------------AG 201

Query: 177 KGEP-------VDASKAGGKQKRGLRGLFSGMRWHRKDKRAKA-------EAAEGRAPGG 222
            G P             GG    GL    +G +  +  K+ +A       +A  GR+ GG
Sbjct: 202 GGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGG 261

Query: 223 GLILPGSLTASLECVKEETPRAAREPEEPS 252
           GL+    + A L   ++ T    + P++ S
Sbjct: 262 GLM--EEMNAMLARRRKATQVGEKTPKDES 289


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 21/44 (47%), Positives = 21/44 (47%), Gaps = 10/44 (22%)

Query: 123 PRGGGDSGGGGGGRPNPGPPRAA----------GPGGGSLASSS 156
           P GGG   GG GG P PGPP A           GPGGGS    S
Sbjct: 16  PAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPS 59



 Score = 36.2 bits (82), Expect = 0.080
 Identities = 20/40 (50%), Positives = 20/40 (50%), Gaps = 6/40 (15%)

Query: 123 PRGGGDSG-GGGGGRPNPGPPRA-----AGPGGGSLASSS 156
           P  GG  G GG GG P PGPP A      GPGGG     S
Sbjct: 15  PPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGS 54



 Score = 33.1 bits (74), Expect = 0.68
 Identities = 17/32 (53%), Positives = 17/32 (53%), Gaps = 4/32 (12%)

Query: 123 PRGGGDSGGGGGGRPNPGPPRAAG----PGGG 150
           P G GD GGGG G   PG   A G    PGGG
Sbjct: 34  PPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGG 65



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 14/34 (41%), Positives = 17/34 (50%)

Query: 125 GGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVA 158
           GGG  GGG GG    GP +  G GG  +   + A
Sbjct: 42  GGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFA 75


>gi|239756433 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 513

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 57/226 (25%), Positives = 87/226 (38%), Gaps = 37/226 (16%)

Query: 85  GVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRA 144
           G++ +G G ++   GL R      LA+V     GR E+ +    +G G  G      P+ 
Sbjct: 145 GLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRAEDLQ----AGAGPRGAAEAQAPQL 200

Query: 145 AGPGGGSLASSSVAKSHSFFSLLKKN---GRSENGKGEPVDASKAGGKQKRGLRG----- 196
            G G   LA+    ++ +  +  ++    GR+ +G G P        +Q+R   G     
Sbjct: 201 LGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHG-GLPAPQHAVAVEQQRVHVGQQRLC 259

Query: 197 -----------LFSGMRWHRKDKRAKAEAAE----GRAPGGGLILPGSLTASLECVKEET 241
                      + +G+R  R+ +R  A AA       A  G L  PG+L           
Sbjct: 260 PLGAQPHAAGVVATGLR--RRHRRPPAAAARRPLLAAARRGALPAPGALIGP-------A 310

Query: 242 PRAAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKP 287
           PRA R       + P  PAGCG      E   G   D  +P  G+P
Sbjct: 311 PRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRP 356


>gi|239753184 PREDICTED: similar to hCG2040565 [Homo sapiens]
          Length = 197

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 45/187 (24%), Positives = 74/187 (39%), Gaps = 39/187 (20%)

Query: 275 PSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYL-------QEFWDMLSQT 327
           P C+K +P PGKP L      V++ QG         + D + L       Q+ +  L + 
Sbjct: 29  PQCEKLLPAPGKPGLR-----VISRQG----KVGWIDYDSSLLLHTITSPQDSFLGLRRG 79

Query: 328 EEQGPEPQEGAAKVA-------AALETKVVPE--TPKDTRCVEAAKDASSVKRRRLNRIP 378
           E   P  Q   A  +        A+    +P+  T  D +  +A  D    +  RL+  P
Sbjct: 80  ENDPPTDQSLCAAASRAQHLSPTAVTAATLPKRKTEGDVKGDKAKVDTPQRRSTRLSAKP 139

Query: 379 IEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSGDALYD 438
             P P+ +PK    ++ E VP   +G             + +GK+   P +   GDA+ D
Sbjct: 140 APPKPEPKPKKAPAKKGEKVPKGKKG------------KADAGKEGNYPAE--KGDAITD 185

Query: 439 LYADPDG 445
              + +G
Sbjct: 186 QAREAEG 192


>gi|239750970 PREDICTED: hypothetical protein XP_002347634 [Homo
           sapiens]
          Length = 513

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 57/226 (25%), Positives = 87/226 (38%), Gaps = 37/226 (16%)

Query: 85  GVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRA 144
           G++ +G G ++   GL R      LA+V     GR E+ +    +G G  G      P+ 
Sbjct: 145 GLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRAEDLQ----AGAGPRGAAEAQAPQL 200

Query: 145 AGPGGGSLASSSVAKSHSFFSLLKKN---GRSENGKGEPVDASKAGGKQKRGLRG----- 196
            G G   LA+    ++ +  +  ++    GR+ +G G P        +Q+R   G     
Sbjct: 201 LGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHG-GLPAPQHAVAVEQQRVHVGQQRLC 259

Query: 197 -----------LFSGMRWHRKDKRAKAEAAE----GRAPGGGLILPGSLTASLECVKEET 241
                      + +G+R  R+ +R  A AA       A  G L  PG+L           
Sbjct: 260 PLGAQPHAAGVVATGLR--RRHRRPPAAAARRPLLAAARRGALPAPGALIGP-------A 310

Query: 242 PRAAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKP 287
           PRA R       + P  PAGCG      E   G   D  +P  G+P
Sbjct: 311 PRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRP 356


>gi|239747758 PREDICTED: hypothetical protein XP_002348261 [Homo
           sapiens]
          Length = 197

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 45/187 (24%), Positives = 74/187 (39%), Gaps = 39/187 (20%)

Query: 275 PSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYL-------QEFWDMLSQT 327
           P C+K +P PGKP L      V++ QG         + D + L       Q+ +  L + 
Sbjct: 29  PQCEKLLPAPGKPGLR-----VISRQG----KVGWIDYDSSLLLHTITSPQDSFLGLRRG 79

Query: 328 EEQGPEPQEGAAKVA-------AALETKVVPE--TPKDTRCVEAAKDASSVKRRRLNRIP 378
           E   P  Q   A  +        A+    +P+  T  D +  +A  D    +  RL+  P
Sbjct: 80  ENDPPTDQSLCAAASRAQHLSPTAVTAATLPKRKTEGDVKGDKAKVDTPQRRSTRLSAKP 139

Query: 379 IEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSGDALYD 438
             P P+ +PK    ++ E VP   +G             + +GK+   P +   GDA+ D
Sbjct: 140 APPKPEPKPKKAPAKKGEKVPKGKKG------------KADAGKEGNYPAE--KGDAITD 185

Query: 439 LYADPDG 445
              + +G
Sbjct: 186 QAREAEG 192


>gi|239745376 PREDICTED: hypothetical protein XP_002343484 [Homo
           sapiens]
          Length = 513

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 57/226 (25%), Positives = 87/226 (38%), Gaps = 37/226 (16%)

Query: 85  GVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRA 144
           G++ +G G ++   GL R      LA+V     GR E+ +    +G G  G      P+ 
Sbjct: 145 GLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRAEDLQ----AGAGPRGAAEAQAPQL 200

Query: 145 AGPGGGSLASSSVAKSHSFFSLLKKN---GRSENGKGEPVDASKAGGKQKRGLRG----- 196
            G G   LA+    ++ +  +  ++    GR+ +G G P        +Q+R   G     
Sbjct: 201 LGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHG-GLPAPQHAVAVEQQRVHVGQQRLC 259

Query: 197 -----------LFSGMRWHRKDKRAKAEAAE----GRAPGGGLILPGSLTASLECVKEET 241
                      + +G+R  R+ +R  A AA       A  G L  PG+L           
Sbjct: 260 PLGAQPHAAGVVATGLR--RRHRRPPAAAARRPLLAAARRGALPAPGALIGP-------A 310

Query: 242 PRAAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKP 287
           PRA R       + P  PAGCG      E   G   D  +P  G+P
Sbjct: 311 PRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRP 356


>gi|239741624 PREDICTED: hypothetical protein XP_002342251 [Homo
           sapiens]
          Length = 197

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 45/187 (24%), Positives = 74/187 (39%), Gaps = 39/187 (20%)

Query: 275 PSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYL-------QEFWDMLSQT 327
           P C+K +P PGKP L      V++ QG         + D + L       Q+ +  L + 
Sbjct: 29  PQCEKLLPAPGKPGLR-----VISRQG----KVGWIDYDSSLLLHTITSPQDSFLGLRRG 79

Query: 328 EEQGPEPQEGAAKVA-------AALETKVVPE--TPKDTRCVEAAKDASSVKRRRLNRIP 378
           E   P  Q   A  +        A+    +P+  T  D +  +A  D    +  RL+  P
Sbjct: 80  ENDPPTDQSLCAAASRAQHLSPTAVTAATLPKRKTEGDVKGDKAKVDTPQRRSTRLSAKP 139

Query: 379 IEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSGDALYD 438
             P P+ +PK    ++ E VP   +G             + +GK+   P +   GDA+ D
Sbjct: 140 APPKPEPKPKKAPAKKGEKVPKGKKG------------KADAGKEGNYPAE--KGDAITD 185

Query: 439 LYADPDG 445
              + +G
Sbjct: 186 QAREAEG 192


>gi|55956910 meningioma  1 [Homo sapiens]
          Length = 1320

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 51/196 (26%), Positives = 77/196 (39%), Gaps = 24/196 (12%)

Query: 123  PRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVD 182
            P  GG SG    G    GPP     G G    +S++ +++  S    +G+  +G G    
Sbjct: 888  PGPGGPSGTSSSGSKASGPPNPPAQGDG----TSLSPNYTLESTSGNDGKPVSGGG---- 939

Query: 183  ASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEET- 241
              +  G++KR    +  G  +   DK + A  + G APG   + PG   AS   V   + 
Sbjct: 940  -GRGRGRRKRDSGHVSPGTFF---DKYSAAPDS-GGAPG---VSPGQQQASGAAVGGSSA 991

Query: 242  --PRAAREPEEPSQDAPRDPAGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAY 299
               R A  P E +  +P    G   ++ DQ +  G      + G  K   S  N G  A 
Sbjct: 992  GETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIG-----SLDGGAKSDSSSPNVGEFAS 1046

Query: 300  QGGGEEMASPDEVDDT 315
                   A+ DEV  +
Sbjct: 1047 DEVSTSYANEDEVSSS 1062



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 12/18 (66%), Positives = 12/18 (66%)

Query: 125 GGGDSGGGGGGRPNPGPP 142
           GGG SGGGGGG   P  P
Sbjct: 772 GGGSSGGGGGGGAYPPQP 789


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 52/169 (30%), Positives = 65/169 (38%), Gaps = 23/169 (13%)

Query: 76  SGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGG---- 131
           SGG   S  G  ++G   S+G        + DG        SG  + P GG  SGG    
Sbjct: 517 SGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGP 576

Query: 132 ----GGGGRPNPGPPRAAGPGGGSLASSSVAKS---HSFFSLLKKNGRSE-----NGKGE 179
               G GG  N G  + +G G GS       KS    S+F  L ++ + +          
Sbjct: 577 GDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPP 636

Query: 180 PVDASKAGGKQKRG--LRGLFSGMRWHRKD-KRAK----AEAAEGRAPG 221
           P  A   GGK K G   R  F   R   K+ K AK    AE  EG A G
Sbjct: 637 PPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARG 685



 Score = 33.9 bits (76), Expect = 0.40
 Identities = 31/112 (27%), Positives = 45/112 (40%), Gaps = 19/112 (16%)

Query: 118 GRKEEPRGGGDSGGGGGG---RPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSE 174
           G +  P+G  D  G GG      N G     G GGG  ++   + SHS        G   
Sbjct: 469 GEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHS------SGGNQC 522

Query: 175 NGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKA---EAAEGRAPGGG 223
           +G+G+       G +  +G  G  SG     +D +  A    +  G+ PGGG
Sbjct: 523 SGEGQ-------GSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGG 567


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.130    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,501,055
Number of Sequences: 37866
Number of extensions: 1828042
Number of successful extensions: 14684
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 644
Number of HSP's that attempted gapping in prelim test: 10120
Number of HSP's gapped (non-prelim): 3684
length of query: 552
length of database: 18,247,518
effective HSP length: 107
effective length of query: 445
effective length of database: 14,195,856
effective search space: 6317155920
effective search space used: 6317155920
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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