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Search of human proteins with 40068497
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40068497 FAST kinase domains 3 [Homo sapiens]
(662 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40068497 FAST kinase domains 3 [Homo sapiens] 1331 0.0
gi|40217812 cell cycle progression 2 protein isoform 1 [Homo sap... 117 4e-26
gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo... 110 5e-24
gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Hom... 110 5e-24
gi|188497683 FAST kinase domains 1 [Homo sapiens] 97 6e-20
gi|40217810 cell cycle progression 2 protein isoform 2 [Homo sap... 77 4e-14
gi|13569848 cell cycle progression 2 protein isoform 2 [Homo sap... 77 4e-14
gi|11141903 FAST kinase domains 5 [Homo sapiens] 69 1e-11
gi|209969832 FAST kinase domains 2 [Homo sapiens] 67 7e-11
gi|209969830 FAST kinase domains 2 [Homo sapiens] 67 7e-11
gi|45267832 FAST kinase domains 2 [Homo sapiens] 67 7e-11
gi|170784850 SCY1-like 3 isoform 2 [Homo sapiens] 33 0.64
gi|170784842 SCY1-like 3 isoform 1 [Homo sapiens] 33 0.64
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid... 33 1.1
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide... 33 1.1
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated... 33 1.1
gi|222144293 karyopherin alpha 1 [Homo sapiens] 32 1.9
gi|93102375 hypothetical protein LOC10827 [Homo sapiens] 31 4.2
gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens] 30 5.4
gi|6912478 karyopherin alpha 6 [Homo sapiens] 30 5.4
gi|39812229 karyopherin alpha 5 [Homo sapiens] 30 7.1
gi|239753591 PREDICTED: hypothetical protein [Homo sapiens] 30 9.3
>gi|40068497 FAST kinase domains 3 [Homo sapiens]
Length = 662
Score = 1331 bits (3444), Expect = 0.0
Identities = 662/662 (100%), Positives = 662/662 (100%)
Query: 1 MALITLRKNLYRLSDFQMHRALAALKNKPLNHVHKVVKERLCPWLCSRQPEPFGVKFHHA 60
MALITLRKNLYRLSDFQMHRALAALKNKPLNHVHKVVKERLCPWLCSRQPEPFGVKFHHA
Sbjct: 1 MALITLRKNLYRLSDFQMHRALAALKNKPLNHVHKVVKERLCPWLCSRQPEPFGVKFHHA 60
Query: 61 HCKKFHSKNGNDLHPLGGPVFSQVSDCDRLEQNVKNEESQMFYRRLSNLTSSEEVLSFIS 120
HCKKFHSKNGNDLHPLGGPVFSQVSDCDRLEQNVKNEESQMFYRRLSNLTSSEEVLSFIS
Sbjct: 61 HCKKFHSKNGNDLHPLGGPVFSQVSDCDRLEQNVKNEESQMFYRRLSNLTSSEEVLSFIS 120
Query: 121 TMETLPDTMAAGALQRICEVEKKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLVT 180
TMETLPDTMAAGALQRICEVEKKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLVT
Sbjct: 121 TMETLPDTMAAGALQRICEVEKKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLVT 180
Query: 181 ALQALILLHVDPQSSLLLNLVAECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLELII 240
ALQALILLHVDPQSSLLLNLVAECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLELII
Sbjct: 181 ALQALILLHVDPQSSLLLNLVAECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLELII 240
Query: 241 NQLQGEKLETFTPEDIVALYRILQACTEKVDEHQTFLNKINNFSLSIVSNLSPKLISQML 300
NQLQGEKLETFTPEDIVALYRILQACTEKVDEHQTFLNKINNFSLSIVSNLSPKLISQML
Sbjct: 241 NQLQGEKLETFTPEDIVALYRILQACTEKVDEHQTFLNKINNFSLSIVSNLSPKLISQML 300
Query: 301 TALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIYFGHHDTFFTKALEHRVA 360
TALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIYFGHHDTFFTKALEHRVA
Sbjct: 301 TALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIYFGHHDTFFTKALEHRVA 360
Query: 361 AVCLTLDPEVVCRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNY 420
AVCLTLDPEVVCRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNY
Sbjct: 361 AVCLTLDPEVVCRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNY 420
Query: 421 LPPNASALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQG 480
LPPNASALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQG
Sbjct: 421 LPPNASALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQG 480
Query: 481 KESHLDTLSRAQLTQLFLASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYV 540
KESHLDTLSRAQLTQLFLASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYV
Sbjct: 481 KESHLDTLSRAQLTQLFLASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYV 540
Query: 541 KIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLPSTANEDIHKRIALCIDGPKR 600
KIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLPSTANEDIHKRIALCIDGPKR
Sbjct: 541 KIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLPSTANEDIHKRIALCIDGPKR 600
Query: 601 FCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKLFSQNTVHWL 660
FCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKLFSQNTVHWL
Sbjct: 601 FCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKLFSQNTVHWL 660
Query: 661 QE 662
QE
Sbjct: 661 QE 662
>gi|40217812 cell cycle progression 2 protein isoform 1 [Homo
sapiens]
Length = 631
Score = 117 bits (292), Expect = 4e-26
Identities = 134/567 (23%), Positives = 244/567 (43%), Gaps = 42/567 (7%)
Query: 106 LSNLTSSEEVLSFISTMETLPDTMAAGALQRICEV-EKKDGDQGLPKEILENSIFQALCF 164
+ T EE+L + L AA L R+ + +K D+GL +++++ F L
Sbjct: 76 IKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL---LIQDAHFHQLLC 132
Query: 165 QFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLVAECQNRLRKGGMEVRNLCILGES 224
+ + + + +L L +L L + S L ++ E + R+RK ++ ++L L ES
Sbjct: 133 LLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRK--LKYKHLAFLAES 190
Query: 225 LITLHSSGCVTLELIINQLQGEKLETFTPEDIVALYRILQACTEKVDE-HQTFLNKINNF 283
TL S + EL+ L + ED L ++ KV + +N++ +
Sbjct: 191 CATL-SQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMM----KVGHLSEPLMNRLEDK 245
Query: 284 SLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIY 343
L +V + P + ++L L + ++ PL+ + ++V+ T + L V A+
Sbjct: 246 CLELVEHFGPNELRKVLVMLAAQSR-RSVPLLRAISYHLVQKPFSLTKDVLLDVAYAYGK 304
Query: 344 FGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSRELILSK----PILNAVAETFVCQ 399
H T + R+A L+L P + + +C++ L K P+ A A+ + +
Sbjct: 305 LSFHQT----QVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNR 360
Query: 400 TEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLLHS-CSLN 458
+ + + +++ F +LN+ P F + L + P + L+ + C L
Sbjct: 361 AQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQ 420
Query: 459 ECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASVLECPFYKGPKLLPKYQV 518
+ A + +Q L GK S D + +L + ++LE P Y GP LLP V
Sbjct: 421 QAREAELQAVLHPEFHIQFLGGK-SQKDQNTFQKLLHINATALLEYPEYSGP-LLPASAV 478
Query: 519 KSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFV 578
+ TP+ +L +K LLG+ + +V T Y + +D E+ LD +G
Sbjct: 479 APGPSALDRKVTPLQKELQETLK----GLLGSADKGSLEVATQYGWVLDAEVLLDSDGEF 534
Query: 579 LP--------------STANEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGY 624
LP S + KR+A F S SK LLG+ + +RH+ G+
Sbjct: 535 LPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGF 594
Query: 625 QVVQIPYHEIGMLKSRRELVEYLQRKL 651
+V +P++E LKS + YL+ K+
Sbjct: 595 LIVDVPFYEWLELKSEWQKGAYLKDKM 621
>gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo
sapiens]
Length = 549
Score = 110 bits (274), Expect = 5e-24
Identities = 87/308 (28%), Positives = 134/308 (43%), Gaps = 27/308 (8%)
Query: 366 LDPEVVCRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNYLPPNA 425
L P V+ + ++ +R + +L A+A V Q + S + + L+ PFG+LNYLP
Sbjct: 235 LTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLEQ 294
Query: 426 SALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHL 485
+ LE +L P ++ L+ C L C P L +F P F+ + G L
Sbjct: 295 QFM-PCLERILAREAGVAPLATVNILMSLCQLR-CLPFRALHFVFSPGFINYISGTPHAL 352
Query: 486 DTLSRAQLTQLFLASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLT 545
+ R L+ L A LE P Y+GP+L + QV F P + V GL
Sbjct: 353 --IVRRYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLR 410
Query: 546 NLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLP----------------------STA 583
LLG Y + P Y D + G VLP S
Sbjct: 411 QLLGEEKY-RQDLTVPPGYCTDFLLCASSSGAVLPVRTQDPFLPYPPRSCPQGQAASSAT 469
Query: 584 NEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRREL 643
D +R+ L + FC + + LLG A+++RHL L+GYQ++ +P+ E+ + +L
Sbjct: 470 TRDPAQRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLPLPFEELESQRGLPQL 529
Query: 644 VEYLQRKL 651
YL++KL
Sbjct: 530 KSYLRQKL 537
>gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Homo
sapiens]
Length = 408
Score = 110 bits (274), Expect = 5e-24
Identities = 87/308 (28%), Positives = 134/308 (43%), Gaps = 27/308 (8%)
Query: 366 LDPEVVCRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNYLPPNA 425
L P V+ + ++ +R + +L A+A V Q + S + + L+ PFG+LNYLP
Sbjct: 94 LTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLEQ 153
Query: 426 SALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHL 485
+ LE +L P ++ L+ C L C P L +F P F+ + G L
Sbjct: 154 QFM-PCLERILAREAGVAPLATVNILMSLCQLR-CLPFRALHFVFSPGFINYISGTPHAL 211
Query: 486 DTLSRAQLTQLFLASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLT 545
+ R L+ L A LE P Y+GP+L + QV F P + V GL
Sbjct: 212 --IVRRYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLR 269
Query: 546 NLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLP----------------------STA 583
LLG Y + P Y D + G VLP S
Sbjct: 270 QLLGEEKY-RQDLTVPPGYCTDFLLCASSSGAVLPVRTQDPFLPYPPRSCPQGQAASSAT 328
Query: 584 NEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRREL 643
D +R+ L + FC + + LLG A+++RHL L+GYQ++ +P+ E+ + +L
Sbjct: 329 TRDPAQRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLPLPFEELESQRGLPQL 388
Query: 644 VEYLQRKL 651
YL++KL
Sbjct: 389 KSYLRQKL 396
>gi|188497683 FAST kinase domains 1 [Homo sapiens]
Length = 847
Score = 96.7 bits (239), Expect = 6e-20
Identities = 133/518 (25%), Positives = 213/518 (41%), Gaps = 98/518 (18%)
Query: 211 GGMEVRNLCILGE--SLITLHSSGCVTLELI-----INQLQGEKLE-------------- 249
G ME RN C++ S++ H G LEL+ + L ++ E
Sbjct: 349 GDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQELTFLHFQRKEFFAKLRELLLSYLK 408
Query: 250 -TFTPEDIVALYRILQAC-TEKVDE----------HQTFLNKINNFSLSIVSNLS-PKLI 296
+F P ++ L R + + +DE Q LN +++F+ S++ + +
Sbjct: 409 NSFIPTEVSVLVRAISLLPSPHLDEVGISRIEAVLPQCDLNNLSSFATSVLRWIQHDHMY 468
Query: 297 SQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEEL-RRVLEAFIYFGHHDTFFTKAL 355
+TA + L+ KL Y + + H + +L R+ L++ +TF L
Sbjct: 469 LDNMTA-------KQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSL----KGNTFPESLL 517
Query: 356 EHRVAAVCLTLDPEVVCRVME---YCSRELILSKPILNAVAETFVCQTEKFSPRQISALM 412
E +A + +D V E + S LS +L+ +A V Q EK P I A++
Sbjct: 518 EEMIATLQHFMDDINYINVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIPAII 577
Query: 413 EPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKP 472
PF LNY PP L ++ P L+ L S + E P + L IF
Sbjct: 578 RPFSVLNYDPPQRDEFLGTCVQHLNSYLGILDPFILVFLGFSLATLEYFPEDLLKAIFNI 637
Query: 473 LFLQRLQGKESHLDTLSRAQ-------LTQLFLASVLECPFYKGPKLLPKYQVKSFLTPC 525
FL RL +S L+ LS ++ L +L + LECP ++Q+ F
Sbjct: 638 KFLARL---DSQLEILSPSRSARVQFHLMELNRSVCLECP---------EFQIPWFHDRF 685
Query: 526 CSLETP----VDSQLYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLPS 581
C +D + K+ L +LG VLTPY + +D E LD+ LP
Sbjct: 686 CQQYNKGIGGMDGTQQQIFKM-LAEVLGGINCVKASVLTPYYHKVDFECILDKRKKPLPY 744
Query: 582 ---------------TANEDI--------HKRIALCIDGPKRFCSNSKHLLGKEAIKQRH 618
+N +I +RIAL K C N H+ GK A+K+RH
Sbjct: 745 GSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALEFLDSKALCRNIPHMKGKSAMKKRH 804
Query: 619 LQLLGYQVVQIPYHEIG--MLKSRRELVEYLQRKLFSQ 654
L++LGY+V+QI E L ++ ++YL+ +F +
Sbjct: 805 LEILGYRVIQISQFEWNSMALSTKDARMDYLRECIFGE 842
>gi|40217810 cell cycle progression 2 protein isoform 2 [Homo
sapiens]
Length = 521
Score = 77.4 bits (189), Expect = 4e-14
Identities = 73/284 (25%), Positives = 125/284 (44%), Gaps = 22/284 (7%)
Query: 384 LSKPILNAVAETFVC-QTEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVLFTHFNY 442
LS+P++N + + V + + + + +++ F +LN+ P F + L +
Sbjct: 234 LSEPLMNRLEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPG 293
Query: 443 FPPKSLLKLLHS-CSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASV 501
P + L+ + C L + A + +Q L GK S D + +L + ++
Sbjct: 294 LEPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGK-SQKDQNTFQKLLHINATAL 352
Query: 502 LECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKVLTP 561
LE P Y GP LLP V + TP+ +L +K LLG+ + +V T
Sbjct: 353 LEYPEYSGP-LLPASAVAPGPSALDRKVTPLQKELQETLK----GLLGSADKGSLEVATQ 407
Query: 562 YCYTIDVEIKLDEEGFVLP--------------STANEDIHKRIALCIDGPKRFCSNSKH 607
Y + +D E+ LD +G LP S + KR+A F S SK
Sbjct: 408 YGWVLDAEVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKD 467
Query: 608 LLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKL 651
LLG+ + +RH+ G+ +V +P++E LKS + YL+ K+
Sbjct: 468 LLGRFVLARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKM 511
>gi|13569848 cell cycle progression 2 protein isoform 2 [Homo
sapiens]
Length = 521
Score = 77.4 bits (189), Expect = 4e-14
Identities = 73/284 (25%), Positives = 125/284 (44%), Gaps = 22/284 (7%)
Query: 384 LSKPILNAVAETFVC-QTEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVLFTHFNY 442
LS+P++N + + V + + + + +++ F +LN+ P F + L +
Sbjct: 234 LSEPLMNRLEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPG 293
Query: 443 FPPKSLLKLLHS-CSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASV 501
P + L+ + C L + A + +Q L GK S D + +L + ++
Sbjct: 294 LEPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGK-SQKDQNTFQKLLHINATAL 352
Query: 502 LECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKVLTP 561
LE P Y GP LLP V + TP+ +L +K LLG+ + +V T
Sbjct: 353 LEYPEYSGP-LLPASAVAPGPSALDRKVTPLQKELQETLK----GLLGSADKGSLEVATQ 407
Query: 562 YCYTIDVEIKLDEEGFVLP--------------STANEDIHKRIALCIDGPKRFCSNSKH 607
Y + +D E+ LD +G LP S + KR+A F S SK
Sbjct: 408 YGWVLDAEVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKD 467
Query: 608 LLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKL 651
LLG+ + +RH+ G+ +V +P++E LKS + YL+ K+
Sbjct: 468 LLGRFVLARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKM 511
>gi|11141903 FAST kinase domains 5 [Homo sapiens]
Length = 764
Score = 68.9 bits (167), Expect = 1e-11
Identities = 83/425 (19%), Positives = 172/425 (40%), Gaps = 14/425 (3%)
Query: 153 ILENSIFQALCFQFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLVAECQNRLRKGG 212
+L ++ F LC K+ L+ L+A ++L + S+L +C +++ +
Sbjct: 181 LLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMN 240
Query: 213 MEVRNLCILGESLITLHSSGCVTLELIINQLQGEKLETFTPEDIVALYRILQACTEKVDE 272
M+ L ++ + L L + + L + + L ++ E
Sbjct: 241 MD--QLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDL----SLSQLVHLIYVIGENRQV 294
Query: 273 HQTFLNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNE 332
Q + K+ + L + ++ + + + + + ++ K+G ++ H ++
Sbjct: 295 SQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSR 354
Query: 333 ELRRVLEAFIYFGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSRELILSKPILNAV 392
L +++ F + F K + +L + V + YCS L++ ++NAV
Sbjct: 355 SLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAV 414
Query: 393 AETFVCQTEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVL---FTHFNYFPPKSLL 449
A + + + ++ ++ FG LNY PPNA + L + + FN + P+ L
Sbjct: 415 AASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQY-PEHLP 473
Query: 450 KLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASVLECPFYKG 509
L + E PV + P F+ RL + + D L +L L +ECP Y+G
Sbjct: 474 TCLLGLAFLEYFPVELIDFALSPGFV-RLAQERTKFDLLK--ELYTLDGTVGIECPDYRG 530
Query: 510 PKLLPKYQVKSFLTPCCSLETPVDSQ-LYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDV 568
+L Q + E ++S+ + L +LG Y ++ P+ + D+
Sbjct: 531 NRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDL 590
Query: 569 EIKLD 573
E++LD
Sbjct: 591 EVQLD 595
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 580 PSTANEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHE-IGMLK 638
P+ + ++A+ ++C S+ LLG +K+R L LGY+VV++ Y E + +LK
Sbjct: 686 PAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLK 745
Query: 639 -SRRELVEYLQRKLFS 653
+R E + +L K+F+
Sbjct: 746 RTRLEKLAFLHEKVFT 761
>gi|209969832 FAST kinase domains 2 [Homo sapiens]
Length = 710
Score = 66.6 bits (161), Expect = 7e-11
Identities = 116/581 (19%), Positives = 231/581 (39%), Gaps = 33/581 (5%)
Query: 83 QVSDCDRLEQNVKNEESQMFYRRLSNLTSS-EEVLSFISTMETLPDTMAAGALQRICEVE 141
+VS+ D L + K +++ R+LS +S +VL S T P + A+ I +
Sbjct: 138 EVSNEDVLTKETK--PNRISSRKLSEECNSLSDVLDAFSKAPTFPSSNYFTAMWTIAKRL 195
Query: 142 KKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLV 201
D + + + + F LC +E + L+ +L A++ L + + L+ L+
Sbjct: 196 SDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLL 255
Query: 202 AECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLELIINQLQG-EKLETFTPEDIVALY 260
Q R+ E +C+ S + C + ++ + + + ED+ L
Sbjct: 256 RVTQERIN----ECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTL- 310
Query: 261 RILQACTEKVDEHQTFLNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGK 320
+++ C K D K+ +L + S M L ++ ++ L+ + K
Sbjct: 311 QVVMKCIGK-DAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNH-RSLILLDECSK 368
Query: 321 YVVRHVPHFTNEELRRVLEAFIYFGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSR 380
V+ ++ + +L++ +H+ K L VAA V ++
Sbjct: 369 VVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFEN 428
Query: 381 ELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLN--YLPPNASALFRKLENVLFT 438
+++ + V E + + I +++ + LN Y N + + L
Sbjct: 429 LGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTG 488
Query: 439 HFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFL 498
+ + ++LL ++S L P+ ++ + + L + D + +L L
Sbjct: 489 YLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSD---DMKNAYKLHTLDT 545
Query: 499 ASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKV 558
L+ Y L Q+ E P + ++ L++LLG +F+ V
Sbjct: 546 CLKLDDTVYLRDIALSLPQLPR--------ELPSSHTNAKVAEV-LSSLLGGEGHFSKDV 596
Query: 559 LTPYCYTIDVEIKLD-EEGFVLP-----STANEDIHKRIALCIDGPKRFCSNSKHLLGKE 612
P+ Y ID EI++D VLP +T+ DI + LC+ +C S H G
Sbjct: 597 HLPHNYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSR-SAYCLGSSHPRGFL 655
Query: 613 AIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKLFS 653
A+K RHL +G+ V+ + E+ L+ + V +L+ K++S
Sbjct: 656 AMKMRHLNAMGFHVILVNNWEMDKLE-MEDAVTFLKTKIYS 695
>gi|209969830 FAST kinase domains 2 [Homo sapiens]
Length = 710
Score = 66.6 bits (161), Expect = 7e-11
Identities = 116/581 (19%), Positives = 231/581 (39%), Gaps = 33/581 (5%)
Query: 83 QVSDCDRLEQNVKNEESQMFYRRLSNLTSS-EEVLSFISTMETLPDTMAAGALQRICEVE 141
+VS+ D L + K +++ R+LS +S +VL S T P + A+ I +
Sbjct: 138 EVSNEDVLTKETK--PNRISSRKLSEECNSLSDVLDAFSKAPTFPSSNYFTAMWTIAKRL 195
Query: 142 KKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLV 201
D + + + + F LC +E + L+ +L A++ L + + L+ L+
Sbjct: 196 SDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLL 255
Query: 202 AECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLELIINQLQG-EKLETFTPEDIVALY 260
Q R+ E +C+ S + C + ++ + + + ED+ L
Sbjct: 256 RVTQERIN----ECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTL- 310
Query: 261 RILQACTEKVDEHQTFLNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGK 320
+++ C K D K+ +L + S M L ++ ++ L+ + K
Sbjct: 311 QVVMKCIGK-DAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNH-RSLILLDECSK 368
Query: 321 YVVRHVPHFTNEELRRVLEAFIYFGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSR 380
V+ ++ + +L++ +H+ K L VAA V ++
Sbjct: 369 VVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFEN 428
Query: 381 ELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLN--YLPPNASALFRKLENVLFT 438
+++ + V E + + I +++ + LN Y N + + L
Sbjct: 429 LGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTG 488
Query: 439 HFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFL 498
+ + ++LL ++S L P+ ++ + + L + D + +L L
Sbjct: 489 YLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSD---DMKNAYKLHTLDT 545
Query: 499 ASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKV 558
L+ Y L Q+ E P + ++ L++LLG +F+ V
Sbjct: 546 CLKLDDTVYLRDIALSLPQLPR--------ELPSSHTNAKVAEV-LSSLLGGEGHFSKDV 596
Query: 559 LTPYCYTIDVEIKLD-EEGFVLP-----STANEDIHKRIALCIDGPKRFCSNSKHLLGKE 612
P+ Y ID EI++D VLP +T+ DI + LC+ +C S H G
Sbjct: 597 HLPHNYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSR-SAYCLGSSHPRGFL 655
Query: 613 AIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKLFS 653
A+K RHL +G+ V+ + E+ L+ + V +L+ K++S
Sbjct: 656 AMKMRHLNAMGFHVILVNNWEMDKLE-MEDAVTFLKTKIYS 695
>gi|45267832 FAST kinase domains 2 [Homo sapiens]
Length = 710
Score = 66.6 bits (161), Expect = 7e-11
Identities = 116/581 (19%), Positives = 231/581 (39%), Gaps = 33/581 (5%)
Query: 83 QVSDCDRLEQNVKNEESQMFYRRLSNLTSS-EEVLSFISTMETLPDTMAAGALQRICEVE 141
+VS+ D L + K +++ R+LS +S +VL S T P + A+ I +
Sbjct: 138 EVSNEDVLTKETK--PNRISSRKLSEECNSLSDVLDAFSKAPTFPSSNYFTAMWTIAKRL 195
Query: 142 KKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLV 201
D + + + + F LC +E + L+ +L A++ L + + L+ L+
Sbjct: 196 SDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLL 255
Query: 202 AECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLELIINQLQG-EKLETFTPEDIVALY 260
Q R+ E +C+ S + C + ++ + + + ED+ L
Sbjct: 256 RVTQERIN----ECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTL- 310
Query: 261 RILQACTEKVDEHQTFLNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGK 320
+++ C K D K+ +L + S M L ++ ++ L+ + K
Sbjct: 311 QVVMKCIGK-DAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNH-RSLILLDECSK 368
Query: 321 YVVRHVPHFTNEELRRVLEAFIYFGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSR 380
V+ ++ + +L++ +H+ K L VAA V ++
Sbjct: 369 VVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFEN 428
Query: 381 ELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLN--YLPPNASALFRKLENVLFT 438
+++ + V E + + I +++ + LN Y N + + L
Sbjct: 429 LGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTG 488
Query: 439 HFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFL 498
+ + ++LL ++S L P+ ++ + + L + D + +L L
Sbjct: 489 YLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSD---DMKNAYKLHTLDT 545
Query: 499 ASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKV 558
L+ Y L Q+ E P + ++ L++LLG +F+ V
Sbjct: 546 CLKLDDTVYLRDIALSLPQLPR--------ELPSSHTNAKVAEV-LSSLLGGEGHFSKDV 596
Query: 559 LTPYCYTIDVEIKLD-EEGFVLP-----STANEDIHKRIALCIDGPKRFCSNSKHLLGKE 612
P+ Y ID EI++D VLP +T+ DI + LC+ +C S H G
Sbjct: 597 HLPHNYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSR-SAYCLGSSHPRGFL 655
Query: 613 AIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKLFS 653
A+K RHL +G+ V+ + E+ L+ + V +L+ K++S
Sbjct: 656 AMKMRHLNAMGFHVILVNNWEMDKLE-MEDAVTFLKTKIYS 695
>gi|170784850 SCY1-like 3 isoform 2 [Homo sapiens]
Length = 742
Score = 33.5 bits (75), Expect = 0.64
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 291 LSPKLI-SQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIYFGHHDT 349
LSP L S+++ L+ L + + + L ++ +V HFT E+L++V+ + G DT
Sbjct: 329 LSPALFQSRVIPVLLQLFEVHEEHVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLGLRDT 388
Query: 350 --FFTKALEHRVAAVCLTLDPEVV 371
H +A + L PEVV
Sbjct: 389 SDSIVAITLHSLAVLVSLLGPEVV 412
>gi|170784842 SCY1-like 3 isoform 1 [Homo sapiens]
Length = 688
Score = 33.5 bits (75), Expect = 0.64
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 291 LSPKLI-SQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIYFGHHDT 349
LSP L S+++ L+ L + + + L ++ +V HFT E+L++V+ + G DT
Sbjct: 329 LSPALFQSRVIPVLLQLFEVHEEHVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLGLRDT 388
Query: 350 --FFTKALEHRVAAVCLTLDPEVV 371
H +A + L PEVV
Sbjct: 389 SDSIVAITLHSLAVLVSLLGPEVV 412
>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
isoform 2 [Homo sapiens]
Length = 4097
Score = 32.7 bits (73), Expect = 1.1
Identities = 55/207 (26%), Positives = 77/207 (37%), Gaps = 46/207 (22%)
Query: 277 LNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTN----- 331
L KI S+ N S ++ T + L L +K V +P FT+
Sbjct: 1649 LAKILQIDSSVSFNTSHGSFPEVFTTYISLLADTKLDLHLK--GQAVTLLPFFTSLTGGS 1706
Query: 332 -EELRRVLEAFI-----------------YFGHHDTF--FTKALEHRVAAVCLTLDPEVV 371
EELRRVLE I + + D F ALE + + L L EV+
Sbjct: 1707 LEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYVDCMKKFLDALELSQSPMLLELMTEVL 1766
Query: 372 CRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNYLPPNASALFRK 431
CR ++ EL S +A C T+ L+E + +FRK
Sbjct: 1767 CREQQHVMEELFQSS--FRRIARRGSCVTQ-------VGLLE----------SVYEMFRK 1807
Query: 432 LENVLFTHFNYFPPKSLLKLLHSCSLN 458
+ L F +SLL LL CSL+
Sbjct: 1808 DDPRLSFTRQSFVDRSLLTLLWHCSLD 1834
>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
isoform 1 [Homo sapiens]
Length = 4128
Score = 32.7 bits (73), Expect = 1.1
Identities = 55/207 (26%), Positives = 77/207 (37%), Gaps = 46/207 (22%)
Query: 277 LNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTN----- 331
L KI S+ N S ++ T + L L +K V +P FT+
Sbjct: 1649 LAKILQIDSSVSFNTSHGSFPEVFTTYISLLADTKLDLHLK--GQAVTLLPFFTSLTGGS 1706
Query: 332 -EELRRVLEAFI-----------------YFGHHDTF--FTKALEHRVAAVCLTLDPEVV 371
EELRRVLE I + + D F ALE + + L L EV+
Sbjct: 1707 LEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYVDCMKKFLDALELSQSPMLLELMTEVL 1766
Query: 372 CRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNYLPPNASALFRK 431
CR ++ EL S +A C T+ L+E + +FRK
Sbjct: 1767 CREQQHVMEELFQSS--FRRIARRGSCVTQ-------VGLLE----------SVYEMFRK 1807
Query: 432 LENVLFTHFNYFPPKSLLKLLHSCSLN 458
+ L F +SLL LL CSL+
Sbjct: 1808 DDPRLSFTRQSFVDRSLLTLLWHCSLD 1834
>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
catalytic polypeptide [Homo sapiens]
Length = 4096
Score = 32.7 bits (73), Expect = 1.1
Identities = 55/207 (26%), Positives = 77/207 (37%), Gaps = 46/207 (22%)
Query: 277 LNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTN----- 331
L KI S+ N S ++ T + L L +K V +P FT+
Sbjct: 1649 LAKILQIDSSVSFNTSHGSFPEVFTTYISLLADTKLDLHLK--GQAVTLLPFFTSLTGGS 1706
Query: 332 -EELRRVLEAFI-----------------YFGHHDTF--FTKALEHRVAAVCLTLDPEVV 371
EELRRVLE I + + D F ALE + + L L EV+
Sbjct: 1707 LEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYVDCMKKFLDALELSQSPMLLELMTEVL 1766
Query: 372 CRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNYLPPNASALFRK 431
CR ++ EL S +A C T+ L+E + +FRK
Sbjct: 1767 CREQQHVMEELFQSS--FRRIARRGSCVTQ-------VGLLE----------SVYEMFRK 1807
Query: 432 LENVLFTHFNYFPPKSLLKLLHSCSLN 458
+ L F +SLL LL CSL+
Sbjct: 1808 DDPRLSFTRQSFVDRSLLTLLWHCSLD 1834
>gi|222144293 karyopherin alpha 1 [Homo sapiens]
Length = 538
Score = 32.0 bits (71), Expect = 1.9
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
Query: 515 KYQVK-SFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPK---VLTPYCYTIDVEI 570
KY V+ + P C L T +DS++ + GL N+L A + + PYC I+
Sbjct: 417 KYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAY 476
Query: 571 KLDEEGFVLPSTANEDIHKR 590
LD+ F L S N++I+++
Sbjct: 477 GLDKIEF-LQSHENQEIYQK 495
>gi|93102375 hypothetical protein LOC10827 [Homo sapiens]
Length = 505
Score = 30.8 bits (68), Expect = 4.2
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 78 GPVFSQVSDCDRLEQ-NVKNEESQMFYRRLSNLTSSEEVLSFISTMETLPDTMAAGALQR 136
G +F + LE + ++ES++ + + N S EE+ + +E L +T +L
Sbjct: 238 GLLFDEFQGLSHLEALEMLSQESEIKVKSILNSLSGEELETLKVELEQLKETF---SLAE 294
Query: 137 IC--EVEKKDGDQGLPKEILE 155
C E E+K GD+ K+I E
Sbjct: 295 FCEEEEEEKKGDEDFTKDITE 315
>gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]
Length = 1580
Score = 30.4 bits (67), Expect = 5.4
Identities = 12/28 (42%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
Query: 31 NHVHKVVKERLCPWL-CSRQPEPFGVKF 57
+H+H KE +C WL CSR+ +PF ++
Sbjct: 504 DHIHGEKKEFVCRWLDCSREQKPFKAQY 531
>gi|6912478 karyopherin alpha 6 [Homo sapiens]
Length = 536
Score = 30.4 bits (67), Expect = 5.4
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 10/75 (13%)
Query: 522 LTPCCSLETPVDSQLYRYVKIGLTNLL------GARLYFAPKVLTPYCYTIDVEIKLDEE 575
+ P C L T +DS++ + GL N+L G R + + PYC I+ LD+
Sbjct: 423 IKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKR---SGSGVNPYCGLIEEAYGLDKI 479
Query: 576 GFVLPSTANEDIHKR 590
F L S N++I+++
Sbjct: 480 EF-LQSHENQEIYQK 493
>gi|39812229 karyopherin alpha 5 [Homo sapiens]
Length = 539
Score = 30.0 bits (66), Expect = 7.1
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 4/72 (5%)
Query: 522 LTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPK---VLTPYCYTIDVEIKLDEEGFV 578
+ P C L T +DS++ + GL N+L + + + PYC I+ LD+ F
Sbjct: 426 IKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEF- 484
Query: 579 LPSTANEDIHKR 590
L S N++I+++
Sbjct: 485 LQSHENQEIYQK 496
>gi|239753591 PREDICTED: hypothetical protein [Homo sapiens]
Length = 194
Score = 29.6 bits (65), Expect = 9.3
Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 579 LPSTANEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHEIGMLK 638
LPS E + LC GP FC + K L G + ++++ + + I + G+ +
Sbjct: 106 LPSPWREKLCLETGLC-SGPSLFCRSHKVLWGNGVFQMKNVEKNRFTLGTIRKKQFGVSR 164
Query: 639 SRREL---VEYLQRKLFSQN 655
+ + L V++L + +QN
Sbjct: 165 AAQNLKGHVKFLSVDMLAQN 184
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,734,799
Number of Sequences: 37866
Number of extensions: 1088569
Number of successful extensions: 2539
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2497
Number of HSP's gapped (non-prelim): 30
length of query: 662
length of database: 18,247,518
effective HSP length: 109
effective length of query: 553
effective length of database: 14,120,124
effective search space: 7808428572
effective search space used: 7808428572
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.