BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] (663 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] 1297 0.0 gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom... 414 e-115 gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom... 414 e-115 gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H... 414 e-115 gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap... 385 e-107 gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap... 332 9e-91 gi|41281907 StAR-related lipid transfer (START) domain containin... 103 5e-22 gi|16445031 StAR-related lipid transfer (START) domain containin... 103 5e-22 gi|41281898 StAR-related lipid transfer (START) domain containin... 103 5e-22 gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] 99 1e-20 gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] 99 1e-20 gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 91 4e-18 gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 91 4e-18 gi|67906814 Rho GTPase activating protein 19 [Homo sapiens] 90 6e-18 gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 87 5e-17 gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 87 5e-17 gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 87 6e-17 gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 87 6e-17 gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 87 6e-17 gi|194272142 myosin IXB isoform 2 [Homo sapiens] 86 8e-17 gi|33356170 myosin IXB isoform 1 [Homo sapiens] 86 8e-17 gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 85 2e-16 gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 84 3e-16 gi|5803145 ralA binding protein 1 [Homo sapiens] 84 3e-16 gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 82 2e-15 gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 82 2e-15 gi|229094128 active breakpoint cluster region-related protein i... 81 3e-15 gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 81 3e-15 gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 81 3e-15 gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 81 3e-15 >gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] Length = 663 Score = 1297 bits (3357), Expect = 0.0 Identities = 663/663 (100%), Positives = 663/663 (100%) Query: 1 MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP 60 MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP Sbjct: 1 MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP 60 Query: 61 FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS 120 FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS Sbjct: 61 FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS 120 Query: 121 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE 180 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE Sbjct: 121 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE 180 Query: 181 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA 240 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA Sbjct: 181 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA 240 Query: 241 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD 300 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD Sbjct: 241 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD 300 Query: 301 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET 360 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET Sbjct: 301 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET 360 Query: 361 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL 420 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL Sbjct: 361 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL 420 Query: 421 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM 480 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM Sbjct: 421 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM 480 Query: 481 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN 540 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN Sbjct: 481 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN 540 Query: 541 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK Sbjct: 541 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600 Query: 601 ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS 660 ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS Sbjct: 601 ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS 660 Query: 661 KPL 663 KPL Sbjct: 661 KPL 663 >gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo sapiens] Length = 622 Score = 414 bits (1065), Expect = e-115 Identities = 239/618 (38%), Positives = 365/618 (59%), Gaps = 45/618 (7%) Query: 70 LDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESA-- 127 ++ SM+ +W+E+E I++ E +ED + P+EGE E +WL++ GLS L G Sbjct: 24 VESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLD 83 Query: 128 GDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFA---QQRESKET 184 GD QE LSTLT+TQ AAV +R++ ++++R+++K + DVRD+F + S E Sbjct: 84 GDHQE---LLSTLTQTQVAAVCRRLDIYARSVRRQHKT-PVRDVRDVFGVFNSGKMSSEN 139 Query: 185 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK 244 G + L + +K+ + +E E N++ +++EQA Sbjct: 140 GDSGMKGAQLSSGASKFPPAAEPGGL----------QEQAGREEAFNMDSAYSEQAAVLL 189 Query: 245 ESSK-EKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLG 303 + S+ + S +LP F +PK + G TRIGDL+ QDM+KV LALIELTAL D+LG Sbjct: 190 QRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILG 249 Query: 304 IELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363 ++LK+ KA K K ++ LF VPL +LLE D + +P ++PL+ Q L+S +E+RGL+ EG+ Sbjct: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309 Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423 LR+PG+ R+K L Q+LE FY G F+W+ V +DA+ LLK FIR+LP PLL+ EYL AF Sbjct: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369 Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483 V N+P KQ+LQ L+LL+++LP+ NR+ LKALLEFL++V+ ++ NKMT+ NV+ VMA Sbjct: 370 AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMA 429 Query: 484 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKK 543 PNLF+ K + +E +A G A + +++ YQ LLWT+ F+V QVRK N + ++ Sbjct: 430 PNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRR 489 Query: 544 DK---RAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600 + +K L++M DR DK+ + + V ++Q K + + LT K Sbjct: 490 PQLCDAGLKTWLRRMHADR------DKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTK 543 Query: 601 ASDVLARFLSQESGVA----------------QTLKKGEVFLYEIGGNIGERCLDDDTYM 644 + VL +F S + ++++ + LYE+GGNI E LD D Y+ Sbjct: 544 VAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYL 603 Query: 645 KDLYQLNPNAEWVIKSKP 662 DLY+ NP+ EWV+K P Sbjct: 604 LDLYRANPHGEWVLKQNP 621 >gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo sapiens] Length = 622 Score = 414 bits (1065), Expect = e-115 Identities = 239/618 (38%), Positives = 365/618 (59%), Gaps = 45/618 (7%) Query: 70 LDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESA-- 127 ++ SM+ +W+E+E I++ E +ED + P+EGE E +WL++ GLS L G Sbjct: 24 VESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLD 83 Query: 128 GDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFA---QQRESKET 184 GD QE LSTLT+TQ AAV +R++ ++++R+++K + DVRD+F + S E Sbjct: 84 GDHQE---LLSTLTQTQVAAVCRRLDIYARSVRRQHKT-PVRDVRDVFGVFNSGKMSSEN 139 Query: 185 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK 244 G + L + +K+ + +E E N++ +++EQA Sbjct: 140 GDSGMKGAQLSSGASKFPPAAEPGGL----------QEQAGREEAFNMDSAYSEQAAVLL 189 Query: 245 ESSK-EKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLG 303 + S+ + S +LP F +PK + G TRIGDL+ QDM+KV LALIELTAL D+LG Sbjct: 190 QRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILG 249 Query: 304 IELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363 ++LK+ KA K K ++ LF VPL +LLE D + +P ++PL+ Q L+S +E+RGL+ EG+ Sbjct: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309 Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423 LR+PG+ R+K L Q+LE FY G F+W+ V +DA+ LLK FIR+LP PLL+ EYL AF Sbjct: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369 Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483 V N+P KQ+LQ L+LL+++LP+ NR+ LKALLEFL++V+ ++ NKMT+ NV+ VMA Sbjct: 370 AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMA 429 Query: 484 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKK 543 PNLF+ K + +E +A G A + +++ YQ LLWT+ F+V QVRK N + ++ Sbjct: 430 PNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRR 489 Query: 544 DK---RAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600 + +K L++M DR DK+ + + V ++Q K + + LT K Sbjct: 490 PQLCDAGLKTWLRRMHADR------DKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTK 543 Query: 601 ASDVLARFLSQESGVA----------------QTLKKGEVFLYEIGGNIGERCLDDDTYM 644 + VL +F S + ++++ + LYE+GGNI E LD D Y+ Sbjct: 544 VAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYL 603 Query: 645 KDLYQLNPNAEWVIKSKP 662 DLY+ NP+ EWV+K P Sbjct: 604 LDLYRANPHGEWVLKQNP 621 >gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo sapiens] Length = 622 Score = 414 bits (1065), Expect = e-115 Identities = 239/618 (38%), Positives = 365/618 (59%), Gaps = 45/618 (7%) Query: 70 LDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESA-- 127 ++ SM+ +W+E+E I++ E +ED + P+EGE E +WL++ GLS L G Sbjct: 24 VESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLD 83 Query: 128 GDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFA---QQRESKET 184 GD QE LSTLT+TQ AAV +R++ ++++R+++K + DVRD+F + S E Sbjct: 84 GDHQE---LLSTLTQTQVAAVCRRLDIYARSVRRQHKT-PVRDVRDVFGVFNSGKMSSEN 139 Query: 185 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK 244 G + L + +K+ + +E E N++ +++EQA Sbjct: 140 GDSGMKGAQLSSGASKFPPAAEPGGL----------QEQAGREEAFNMDSAYSEQAAVLL 189 Query: 245 ESSK-EKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLG 303 + S+ + S +LP F +PK + G TRIGDL+ QDM+KV LALIELTAL D+LG Sbjct: 190 QRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILG 249 Query: 304 IELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363 ++LK+ KA K K ++ LF VPL +LLE D + +P ++PL+ Q L+S +E+RGL+ EG+ Sbjct: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309 Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423 LR+PG+ R+K L Q+LE FY G F+W+ V +DA+ LLK FIR+LP PLL+ EYL AF Sbjct: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369 Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483 V N+P KQ+LQ L+LL+++LP+ NR+ LKALLEFL++V+ ++ NKMT+ NV+ VMA Sbjct: 370 AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMA 429 Query: 484 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKK 543 PNLF+ K + +E +A G A + +++ YQ LLWT+ F+V QVRK N + ++ Sbjct: 430 PNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRR 489 Query: 544 DK---RAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600 + +K L++M DR DK+ + + V ++Q K + + LT K Sbjct: 490 PQLCDAGLKTWLRRMHADR------DKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTK 543 Query: 601 ASDVLARFLSQESGVA----------------QTLKKGEVFLYEIGGNIGERCLDDDTYM 644 + VL +F S + ++++ + LYE+GGNI E LD D Y+ Sbjct: 544 VAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYL 603 Query: 645 KDLYQLNPNAEWVIKSKP 662 DLY+ NP+ EWV+K P Sbjct: 604 LDLYRANPHGEWVLKQNP 621 >gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sapiens] Length = 570 Score = 385 bits (989), Expect = e-107 Identities = 204/457 (44%), Positives = 295/457 (64%), Gaps = 20/457 (4%) Query: 215 EKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTT 274 EK IPPE +++ EVS++E + +K K + K +D L F + K + G T Sbjct: 117 EKNIPPEAE-----ELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLT 171 Query: 275 RIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQ 334 GDL+ +DMKK+ HL+LIELTA +D GI+LK+ K K+K +D+G+F VPLT LL+ D+ Sbjct: 172 EAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDR 231 Query: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394 +K PG+++PL+ QK ++EE GLE+EG+ R+ G ++K +EL+AKF F W+ + Sbjct: 232 KKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKM 291 Query: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDT 453 +AA +LK F RELP L VEY+ AF ++ P K Q QAL+L+V+ LPDANRD Sbjct: 292 CHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDA 351 Query: 454 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMH 513 +AL+ F +VI N+ KN+M++ N++ VMAPNLF + K S+ E ++A A+ + Sbjct: 352 AQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIR 408 Query: 514 LLIKYQKLLWTIPKFIVNQVRKQN--TENHKKDKRAMKKLLKKMAYDREK--------YE 563 L++KYQK+LW +P F++ QVR+ N T KK +++KLL++ +RE + Sbjct: 409 LMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQ 468 Query: 564 KQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQES-GVAQTLKKG 622 K + +DVP+GVIRV AP LSKVSMAIQL + KA D+LA+F + S G ++ +K Sbjct: 469 KSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSSECIKIQ 528 Query: 623 EVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIK 659 LYEIGGNIGE CLD D Y+ D+Y++NP AEWVIK Sbjct: 529 NQRLYEIGGNIGEHCLDPDAYILDVYRINPQAEWVIK 565 >gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sapiens] Length = 563 Score = 332 bits (850), Expect = 9e-91 Identities = 176/405 (43%), Positives = 259/405 (63%), Gaps = 19/405 (4%) Query: 215 EKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTT 274 EK IPPE +++ EVS++E + +K K + K +D L F + K + G T Sbjct: 117 EKNIPPEAE-----ELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLT 171 Query: 275 RIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQ 334 GDL+ +DMKK+ HL+LIELTA +D GI+LK+ K K+K +D+G+F VPLT LL+ D+ Sbjct: 172 EAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDR 231 Query: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394 +K PG+++PL+ QK ++EE GLE+EG+ R+ G ++K +EL+AKF F W+ + Sbjct: 232 KKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKM 291 Query: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDT 453 +AA +LK F RELP L VEY+ AF ++ P K Q QAL+L+V+ LPDANRD Sbjct: 292 CHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDA 351 Query: 454 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMH 513 +AL+ F +VI N+ KN+M++ N++ VMAPNLF + K S+ E ++A A+ + Sbjct: 352 AQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIR 408 Query: 514 LLIKYQKLLWTIPKFIVNQVRKQN--TENHKKDKRAMKKLLKKMAYDREK--------YE 563 L++KYQK+LW +P F++ QVR+ N T KK +++KLL++ +RE + Sbjct: 409 LMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQ 468 Query: 564 KQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARF 608 K + +DVP+GVIRV AP LSKVSMAIQL + KA D+LA+F Sbjct: 469 KSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKF 513 >gi|41281907 StAR-related lipid transfer (START) domain containing 13 isoform beta [Homo sapiens] Length = 1105 Score = 103 bits (257), Expect = 5e-22 Identities = 95/370 (25%), Positives = 169/370 (45%), Gaps = 56/370 (15%) Query: 206 DEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLP--- 262 D N V E + P +D+ +V+ +LN+ E + ++ G A+L Sbjct: 527 DFEGNSVSEGRTTP--------SDVERDVT----SLNESEPPGVRDRRDSGVGASLTRPN 574 Query: 263 ------SFRL---PKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQ----- 308 SF+L P+ + I + + +L+ LTA+ + + K Sbjct: 575 RRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWS 634 Query: 309 ----QKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363 K +K+ KD +F VPL +++ G +P Q+ + + L+ GL Sbjct: 635 VPKFMKRMKVPDYKDKAVFGVPLIVHVQRT-----GQPLPQSIQQALRYLRSNCLDQVGL 689 Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423 R G RI L +++ F E N+E +D A ++K F R+LP+PL + + + F Sbjct: 690 FRKSGVKSRIHAL-RQMNENFPENV-NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETF 747 Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483 + +K+Q+LQA+ ++LL D NR+ L+ LL FL V++ E+N+MT MN+A+ +A Sbjct: 748 LHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLA 807 Query: 484 PNLFMCHALGLKSSE---QREFVMA-----------AGTANTMHLLIKYQKLLWTIPKFI 529 P+LF + L +SS Q+++ A H++++ + L+ +P + Sbjct: 808 PSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDR-LFEVPHEL 866 Query: 530 VNQVRKQNTE 539 V Q R E Sbjct: 867 VAQSRNSYVE 876 >gi|16445031 StAR-related lipid transfer (START) domain containing 13 isoform gamma [Homo sapiens] Length = 995 Score = 103 bits (257), Expect = 5e-22 Identities = 95/370 (25%), Positives = 169/370 (45%), Gaps = 56/370 (15%) Query: 206 DEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLP--- 262 D N V E + P +D+ +V+ +LN+ E + ++ G A+L Sbjct: 417 DFEGNSVSEGRTTP--------SDVERDVT----SLNESEPPGVRDRRDSGVGASLTRPN 464 Query: 263 ------SFRL---PKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQ----- 308 SF+L P+ + I + + +L+ LTA+ + + K Sbjct: 465 RRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWS 524 Query: 309 ----QKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363 K +K+ KD +F VPL +++ G +P Q+ + + L+ GL Sbjct: 525 VPKFMKRMKVPDYKDKAVFGVPLIVHVQRT-----GQPLPQSIQQALRYLRSNCLDQVGL 579 Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423 R G RI L +++ F E N+E +D A ++K F R+LP+PL + + + F Sbjct: 580 FRKSGVKSRIHAL-RQMNENFPENV-NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETF 637 Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483 + +K+Q+LQA+ ++LL D NR+ L+ LL FL V++ E+N+MT MN+A+ +A Sbjct: 638 LHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLA 697 Query: 484 PNLFMCHALGLKSSE---QREFVMA-----------AGTANTMHLLIKYQKLLWTIPKFI 529 P+LF + L +SS Q+++ A H++++ + L+ +P + Sbjct: 698 PSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDR-LFEVPHEL 756 Query: 530 VNQVRKQNTE 539 V Q R E Sbjct: 757 VAQSRNSYVE 766 >gi|41281898 StAR-related lipid transfer (START) domain containing 13 isoform alpha [Homo sapiens] Length = 1113 Score = 103 bits (257), Expect = 5e-22 Identities = 95/370 (25%), Positives = 169/370 (45%), Gaps = 56/370 (15%) Query: 206 DEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLP--- 262 D N V E + P +D+ +V+ +LN+ E + ++ G A+L Sbjct: 535 DFEGNSVSEGRTTP--------SDVERDVT----SLNESEPPGVRDRRDSGVGASLTRPN 582 Query: 263 ------SFRL---PKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQ----- 308 SF+L P+ + I + + +L+ LTA+ + + K Sbjct: 583 RRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWS 642 Query: 309 ----QKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363 K +K+ KD +F VPL +++ G +P Q+ + + L+ GL Sbjct: 643 VPKFMKRMKVPDYKDKAVFGVPLIVHVQRT-----GQPLPQSIQQALRYLRSNCLDQVGL 697 Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423 R G RI L +++ F E N+E +D A ++K F R+LP+PL + + + F Sbjct: 698 FRKSGVKSRIHAL-RQMNENFPENV-NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETF 755 Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483 + +K+Q+LQA+ ++LL D NR+ L+ LL FL V++ E+N+MT MN+A+ +A Sbjct: 756 LHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLA 815 Query: 484 PNLFMCHALGLKSSE---QREFVMA-----------AGTANTMHLLIKYQKLLWTIPKFI 529 P+LF + L +SS Q+++ A H++++ + L+ +P + Sbjct: 816 PSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDR-LFEVPHEL 874 Query: 530 VNQVRKQNTE 539 V Q R E Sbjct: 875 VAQSRNSYVE 884 >gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] Length = 1528 Score = 99.4 bits (246), Expect = 1e-20 Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 8/195 (4%) Query: 307 KQQKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLR 365 K K +K+ KD +F VPLT +++ G +P Q+ + + L+ GL R Sbjct: 1060 KFMKRIKVPDYKDRSVFGVPLTVNVQRT-----GQPLPQSIQQAMRYLRNHCLDQVGLFR 1114 Query: 366 IPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQA 425 G RI+ L Q E N+E +D A +LK + R+LP+PL++ + + F Sbjct: 1115 KSGVKSRIQALRQMNEGAI--DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQ 1172 Query: 426 VQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPN 485 + K Q+LQA+ ++LLPD NR+ L+ LL FL V ++N+MT N+A+ +AP+ Sbjct: 1173 IYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPS 1232 Query: 486 LFMCHALGLKSSEQR 500 LF + L ++S R Sbjct: 1233 LFHLNTLKRENSSPR 1247 >gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] Length = 1091 Score = 99.4 bits (246), Expect = 1e-20 Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 8/195 (4%) Query: 307 KQQKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLR 365 K K +K+ KD +F VPLT +++ G +P Q+ + + L+ GL R Sbjct: 623 KFMKRIKVPDYKDRSVFGVPLTVNVQRT-----GQPLPQSIQQAMRYLRNHCLDQVGLFR 677 Query: 366 IPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQA 425 G RI+ L Q E N+E +D A +LK + R+LP+PL++ + + F Sbjct: 678 KSGVKSRIQALRQMNEGAI--DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQ 735 Query: 426 VQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPN 485 + K Q+LQA+ ++LLPD NR+ L+ LL FL V ++N+MT N+A+ +AP+ Sbjct: 736 IYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPS 795 Query: 486 LFMCHALGLKSSEQR 500 LF + L ++S R Sbjct: 796 LFHLNTLKRENSSPR 810 >gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sapiens] Length = 521 Score = 90.5 bits (223), Expect = 4e-18 Identities = 59/168 (35%), Positives = 90/168 (53%), Gaps = 9/168 (5%) Query: 321 LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQEL 380 +F L AL E+++ R+P Q+ I +E RGL+ +GL RI G I+ L ++ Sbjct: 326 VFGCALAALCERERS-----RVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 380 Query: 381 E--AKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438 + + WE V H LKLF RELP+PL + + F A L + ++ + Sbjct: 381 DHDERLDLDDGRWEDV--HVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRC 438 Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486 + LV LP N DTL+ L + L RVI++ E+N+M+V +VA+V P L Sbjct: 439 VRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 486 >gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sapiens] Length = 548 Score = 90.5 bits (223), Expect = 4e-18 Identities = 59/168 (35%), Positives = 90/168 (53%), Gaps = 9/168 (5%) Query: 321 LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQEL 380 +F L AL E+++ R+P Q+ I +E RGL+ +GL RI G I+ L ++ Sbjct: 353 VFGCALAALCERERS-----RVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 407 Query: 381 E--AKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438 + + WE V H LKLF RELP+PL + + F A L + ++ + Sbjct: 408 DHDERLDLDDGRWEDV--HVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRC 465 Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486 + LV LP N DTL+ L + L RVI++ E+N+M+V +VA+V P L Sbjct: 466 VRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 513 >gi|67906814 Rho GTPase activating protein 19 [Homo sapiens] Length = 494 Score = 90.1 bits (222), Expect = 6e-18 Identities = 60/189 (31%), Positives = 102/189 (53%), Gaps = 23/189 (12%) Query: 356 RGLETEGLLRIPGAAIRIKNLCQELEAKFYEGT-FNWESVKQH--DAASLLKLFIRELPQ 412 + L EGL R+PG ++R + L L GT + ES + H D A+LLK+F+ ELP+ Sbjct: 134 KNLRVEGLFRVPGNSVRQQILRDALN----NGTDIDLESGEFHSNDVATLLKMFLGELPE 189 Query: 413 PLLSVEYLKAFQAVQ------------NLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460 PLL+ ++ A + N+P K +Q++AL LL ++LP NR+ LK LL+ Sbjct: 190 PLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDL 249 Query: 461 LQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQK 520 L + ++KNKM+ N+A++ AP++ + ++ + +G M +IK+ + Sbjct: 250 LYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSG----MAFMIKHSQ 305 Query: 521 LLWTIPKFI 529 L+ P +I Sbjct: 306 KLFKAPAYI 314 >gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] Length = 698 Score = 87.0 bits (214), Expect = 5e-17 Identities = 67/200 (33%), Positives = 98/200 (49%), Gaps = 18/200 (9%) Query: 334 QRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKF--YEGTFNW 391 +RK PL+ ++ + I ERGL EGL R+PG A NL ++L+ F E Sbjct: 164 ERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQA----NLVRDLQDSFDCGEKPLFD 219 Query: 392 ESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLL--VILLPDA 449 + H ASLLKL++RELP+P++ + F + L TK + L L V LP A Sbjct: 220 STTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQA 279 Query: 450 NRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509 N + L+ + +FL V NKM+V N+A V PN+ L+ + + GT+ Sbjct: 280 NYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNI-------LRPQVEDPVTIMEGTS 332 Query: 510 NTMHL---LIKYQKLLWTIP 526 HL LI+ L+T P Sbjct: 333 LVQHLMTVLIRKHSQLFTAP 352 >gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] Length = 818 Score = 87.0 bits (214), Expect = 5e-17 Identities = 58/202 (28%), Positives = 100/202 (49%), Gaps = 2/202 (0%) Query: 292 LIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLIS 351 LIE+ A Y + L Q +IK + P ++ + G I + ++ Sbjct: 218 LIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVT 277 Query: 352 RIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELP 411 + E G++ EGL R+ +A ++K L L+ + S H A LK ++RELP Sbjct: 278 MLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD--VQEYSADPHAIAGALKSYLRELP 335 Query: 412 QPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKN 471 +PL++ E + N+ + ++LQAL LP AN + ++ L++FL ++ + ++ N Sbjct: 336 EPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVN 395 Query: 472 KMTVMNVAMVMAPNLFMCHALG 493 KMT N+A+V+ PNL A G Sbjct: 396 KMTPSNMAIVLGPNLLWPQAEG 417 >gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] Length = 771 Score = 86.7 bits (213), Expect = 6e-17 Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%) Query: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400 ++P + +E+ GL+T G+ R+ + R++ L +E + SV HD A Sbjct: 206 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 263 Query: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460 +LLK F+R++P PLL+ E AF L ++QL L LL+ LLP N DTL LL+F Sbjct: 264 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 322 Query: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509 L V DN K NKMT +N+A + PNL KSS++ V ++ A Sbjct: 323 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 378 Query: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533 + +I+ + L+ +P + N+V Sbjct: 379 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 409 >gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapiens] Length = 765 Score = 86.7 bits (213), Expect = 6e-17 Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%) Query: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400 ++P + +E+ GL+T G+ R+ + R++ L +E + SV HD A Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 466 Query: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460 +LLK F+R++P PLL+ E AF L ++QL L LL+ LLP N DTL LL+F Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525 Query: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509 L V DN K NKMT +N+A + PNL KSS++ V ++ A Sbjct: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 581 Query: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533 + +I+ + L+ +P + N+V Sbjct: 582 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 612 >gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapiens] Length = 974 Score = 86.7 bits (213), Expect = 6e-17 Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%) Query: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400 ++P + +E+ GL+T G+ R+ + R++ L +E + SV HD A Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 466 Query: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460 +LLK F+R++P PLL+ E AF L ++QL L LL+ LLP N DTL LL+F Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525 Query: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509 L V DN K NKMT +N+A + PNL KSS++ V ++ A Sbjct: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 581 Query: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533 + +I+ + L+ +P + N+V Sbjct: 582 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 612 >gi|194272142 myosin IXB isoform 2 [Homo sapiens] Length = 2022 Score = 86.3 bits (212), Expect = 8e-17 Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 2/148 (1%) Query: 342 IPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAAS 401 +P++ +KL+ +E GL TEGL R GAA R + L Q L+ E+ H Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD--PAAVKLENFPIHAITG 1769 Query: 402 LLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFL 461 +LK ++RELP+PL++ F LP K++QL A+ ++ LP+AN ++L+ L+ L Sbjct: 1770 VLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHL 1829 Query: 462 QRVIDNKEKNKMTVMNVAMVMAPNLFMC 489 +V ++ N+M+ +A++ AP L C Sbjct: 1830 VKVALLEDVNRMSPGALAIIFAPCLLRC 1857 >gi|33356170 myosin IXB isoform 1 [Homo sapiens] Length = 2157 Score = 86.3 bits (212), Expect = 8e-17 Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 2/148 (1%) Query: 342 IPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAAS 401 +P++ +KL+ +E GL TEGL R GAA R + L Q L+ E+ H Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD--PAAVKLENFPIHAITG 1769 Query: 402 LLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFL 461 +LK ++RELP+PL++ F LP K++QL A+ ++ LP+AN ++L+ L+ L Sbjct: 1770 VLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHL 1829 Query: 462 QRVIDNKEKNKMTVMNVAMVMAPNLFMC 489 +V ++ N+M+ +A++ AP L C Sbjct: 1830 VKVALLEDVNRMSPGALAIIFAPCLLRC 1857 >gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] Length = 846 Score = 85.1 bits (209), Expect = 2e-16 Identities = 50/148 (33%), Positives = 80/148 (54%), Gaps = 7/148 (4%) Query: 342 IPLIFQKLISRIEERGLETEGLLRIPG--AAIRIKNLCQELEAKFYEGTFNWESVKQHDA 399 +P + I +EE GL+ +G+ R+ G A I+ + K WE + H Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDI--HVI 726 Query: 400 ASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALL 458 LK+F RELP+PL + + F A++ P +Q++ A+ L+ LP N+DT++ L Sbjct: 727 TGALKMFFRELPEPLFTFNHFNDFVNAIKQEP--RQRVAAVKDLIRQLPKPNQDTMQILF 784 Query: 459 EFLQRVIDNKEKNKMTVMNVAMVMAPNL 486 L+RVI+N EKN+MT ++A+V P L Sbjct: 785 RHLRRVIENGEKNRMTYQSIAIVFGPTL 812 >gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] Length = 1397 Score = 84.3 bits (207), Expect = 3e-16 Identities = 52/160 (32%), Positives = 83/160 (51%), Gaps = 5/160 (3%) Query: 330 LEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTF 389 LE+ Q R+PLI +E RGLE+ G+ R+PG + +L ++L G Sbjct: 813 LEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG--PGDI 870 Query: 390 NWESVKQHDA---ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILL 446 N + + D +SLLK F R+LP+PL + + F + +++++ L L+ L Sbjct: 871 NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL 930 Query: 447 PDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486 P +TLK L+ L+ + D+ EKNKM N+A+V P L Sbjct: 931 PGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTL 970 >gi|5803145 ralA binding protein 1 [Homo sapiens] Length = 655 Score = 84.3 bits (207), Expect = 3e-16 Identities = 49/167 (29%), Positives = 95/167 (56%), Gaps = 6/167 (3%) Query: 321 LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQEL 380 +F +PL +E+ G+R+P +F++ I +E+ G++ EG+ R+ G IK+ EL Sbjct: 189 IFGIPLADAVERTMM-YDGIRLPAVFRECIDYVEKYGMKCEGIYRVSG----IKSKVDEL 243 Query: 381 EAKF-YEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQAL 439 +A + E + N E + + ASLLK ++R+LP+ LL+ E + F+ T+ +++Q Sbjct: 244 KAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEF 303 Query: 440 NLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486 L+ LP+ N + L+ + VI + + KM + N+++V++P + Sbjct: 304 QRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350 >gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sapiens] Length = 731 Score = 82.0 bits (201), Expect = 2e-15 Identities = 53/169 (31%), Positives = 83/169 (49%), Gaps = 22/169 (13%) Query: 339 GMRIPLIFQKLISRIEERGLETEGLLRIPG---AAIRIKNLCQELEAKFYEGTF------ 389 G +P + I+ +++RGL+ +G+ R+ G +++ L A +G + Sbjct: 533 GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQP 592 Query: 390 -----------NWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438 W+ + H LKLF+RELPQPL+ L F+A L +Q L Sbjct: 593 GQEGRLDLDSTEWDDI--HVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQ 650 Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLF 487 + L+ +P N DTL+ LLE L RVI + +KN+MT N+ +V P LF Sbjct: 651 IQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 699 >gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sapiens] Length = 547 Score = 82.0 bits (201), Expect = 2e-15 Identities = 53/169 (31%), Positives = 83/169 (49%), Gaps = 22/169 (13%) Query: 339 GMRIPLIFQKLISRIEERGLETEGLLRIPG---AAIRIKNLCQELEAKFYEGTF------ 389 G +P + I+ +++RGL+ +G+ R+ G +++ L A +G + Sbjct: 349 GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQP 408 Query: 390 -----------NWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438 W+ + H LKLF+RELPQPL+ L F+A L +Q L Sbjct: 409 GQEGRLDLDSTEWDDI--HVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQ 466 Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLF 487 + L+ +P N DTL+ LLE L RVI + +KN+MT N+ +V P LF Sbjct: 467 IQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 515 >gi|229094128 active breakpoint cluster region-related protein isoform c [Homo sapiens] Length = 813 Score = 81.3 bits (199), Expect = 3e-15 Identities = 62/212 (29%), Positives = 104/212 (49%), Gaps = 9/212 (4%) Query: 279 LAPQDMK-KVCHLALIELTALYDVLGIELKQQKAVKIKT---KDSGLFCVPLTALLEQDQ 334 L PQ ++ K H +IE+ + ++ + +T K +G+F V ++ + ++++ Sbjct: 552 LDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRER 611 Query: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394 KVP I ++ + +E+RG+E G+ RI G A I+ L +A + + Sbjct: 612 SKVP-----YIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM 666 Query: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTL 454 + A LKL+ RELP+PLL+ AF L + + L+ LPD N T Sbjct: 667 DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITF 726 Query: 455 KALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486 LLE L+RV + + NKM++ N+A V P L Sbjct: 727 LFLLEHLKRVAEKEPINKMSLHNLATVFGPTL 758 >gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sapiens] Length = 653 Score = 81.3 bits (199), Expect = 3e-15 Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 21/243 (8%) Query: 343 PLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEG---TFNWESVKQHDA 399 P++ ++ + I +RGL+ EGL R+PG A NL +EL+ F G +F+ + H Sbjct: 58 PMLVEQCVDFIRQRGLKEEGLFRLPGQA----NLVKELQDAFDCGEKPSFD-SNTDVHTV 112 Query: 400 ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQ--LQALNLLVILLPDANRDTLKAL 457 ASLLKL++RELP+P++ + F + L +K+++ ++ L V LP N + LK + Sbjct: 113 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 172 Query: 458 LEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLL-I 516 FL V NKM+V N+A V PN+ L+ + + GT L+ + Sbjct: 173 CRFLDEVQSYSGVNKMSVQNLATVFGPNI-------LRPKVEDPLTIMEGTVVVQQLMSV 225 Query: 517 KYQKLLWTIPKFIVNQVRKQ---NTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTNDAD 573 K PK Q + Q + N + K M +L K + + + S + ++ Sbjct: 226 MISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSE 285 Query: 574 VPQ 576 PQ Sbjct: 286 SPQ 288 >gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sapiens] Length = 655 Score = 81.3 bits (199), Expect = 3e-15 Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 21/243 (8%) Query: 343 PLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEG---TFNWESVKQHDA 399 P++ ++ + I +RGL+ EGL R+PG A NL +EL+ F G +F+ + H Sbjct: 60 PMLVEQCVDFIRQRGLKEEGLFRLPGQA----NLVKELQDAFDCGEKPSFD-SNTDVHTV 114 Query: 400 ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQ--LQALNLLVILLPDANRDTLKAL 457 ASLLKL++RELP+P++ + F + L +K+++ ++ L V LP N + LK + Sbjct: 115 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 174 Query: 458 LEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLL-I 516 FL V NKM+V N+A V PN+ L+ + + GT L+ + Sbjct: 175 CRFLDEVQSYSGVNKMSVQNLATVFGPNI-------LRPKVEDPLTIMEGTVVVQQLMSV 227 Query: 517 KYQKLLWTIPKFIVNQVRKQ---NTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTNDAD 573 K PK Q + Q + N + K M +L K + + + S + ++ Sbjct: 228 MISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSE 287 Query: 574 VPQ 576 PQ Sbjct: 288 SPQ 290 >gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sapiens] Length = 748 Score = 81.3 bits (199), Expect = 3e-15 Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 21/243 (8%) Query: 343 PLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEG---TFNWESVKQHDA 399 P++ ++ + I +RGL+ EGL R+PG A NL +EL+ F G +F+ + H Sbjct: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQA----NLVKELQDAFDCGEKPSFD-SNTDVHTV 207 Query: 400 ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQ--LQALNLLVILLPDANRDTLKAL 457 ASLLKL++RELP+P++ + F + L +K+++ ++ L V LP N + LK + Sbjct: 208 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 267 Query: 458 LEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLL-I 516 FL V NKM+V N+A V PN+ L+ + + GT L+ + Sbjct: 268 CRFLDEVQSYSGVNKMSVQNLATVFGPNI-------LRPKVEDPLTIMEGTVVVQQLMSV 320 Query: 517 KYQKLLWTIPKFIVNQVRKQ---NTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTNDAD 573 K PK Q + Q + N + K M +L K + + + S + ++ Sbjct: 321 MISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSE 380 Query: 574 VPQ 576 PQ Sbjct: 381 SPQ 383 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.129 0.357 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,488,518 Number of Sequences: 37866 Number of extensions: 1018187 Number of successful extensions: 3915 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 115 Number of HSP's successfully gapped in prelim test: 130 Number of HSP's that attempted gapping in prelim test: 3570 Number of HSP's gapped (non-prelim): 364 length of query: 663 length of database: 18,247,518 effective HSP length: 109 effective length of query: 554 effective length of database: 14,120,124 effective search space: 7822548696 effective search space used: 7822548696 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.