Guide to the Human Genome
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Search of human proteins with 39932589

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
         (663 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]          1297   0.0  
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom...   414   e-115
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom...   414   e-115
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H...   414   e-115
gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap...   385   e-107
gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap...   332   9e-91
gi|41281907 StAR-related lipid transfer (START) domain containin...   103   5e-22
gi|16445031 StAR-related lipid transfer (START) domain containin...   103   5e-22
gi|41281898 StAR-related lipid transfer (START) domain containin...   103   5e-22
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]         99   1e-20
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]         99   1e-20
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...    91   4e-18
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...    91   4e-18
gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]            90   6e-18
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]             87   5e-17
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        87   5e-17
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]    87   6e-17
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi...    87   6e-17
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...    87   6e-17
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                       86   8e-17
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                        86   8e-17
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]            85   2e-16
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]           84   3e-16
gi|5803145 ralA binding protein 1 [Homo sapiens]                       84   3e-16
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap...    82   2e-15
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap...    82   2e-15
gi|229094128 active breakpoint cluster region-related  protein i...    81   3e-15
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa...    81   3e-15
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa...    81   3e-15
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...    81   3e-15

>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
          Length = 663

 Score = 1297 bits (3357), Expect = 0.0
 Identities = 663/663 (100%), Positives = 663/663 (100%)

Query: 1   MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP 60
           MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP
Sbjct: 1   MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP 60

Query: 61  FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS 120
           FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS
Sbjct: 61  FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS 120

Query: 121 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE 180
           NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE
Sbjct: 121 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE 180

Query: 181 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA 240
           SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA
Sbjct: 181 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA 240

Query: 241 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD 300
           LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD
Sbjct: 241 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD 300

Query: 301 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET 360
           VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET
Sbjct: 301 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET 360

Query: 361 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL 420
           EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL
Sbjct: 361 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL 420

Query: 421 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM 480
           KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM
Sbjct: 421 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM 480

Query: 481 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN 540
           VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN
Sbjct: 481 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN 540

Query: 541 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600
           HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK
Sbjct: 541 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600

Query: 601 ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS 660
           ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS
Sbjct: 601 ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS 660

Query: 661 KPL 663
           KPL
Sbjct: 661 KPL 663


>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score =  414 bits (1065), Expect = e-115
 Identities = 239/618 (38%), Positives = 365/618 (59%), Gaps = 45/618 (7%)

Query: 70  LDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESA-- 127
           ++  SM+ +W+E+E I++  E  +ED      + P+EGE E +WL++ GLS L G     
Sbjct: 24  VESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLD 83

Query: 128 GDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFA---QQRESKET 184
           GD QE    LSTLT+TQ AAV +R++  ++++R+++K   + DVRD+F      + S E 
Sbjct: 84  GDHQE---LLSTLTQTQVAAVCRRLDIYARSVRRQHKT-PVRDVRDVFGVFNSGKMSSEN 139

Query: 185 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK 244
              G +   L +  +K+    +              +E    E   N++ +++EQA    
Sbjct: 140 GDSGMKGAQLSSGASKFPPAAEPGGL----------QEQAGREEAFNMDSAYSEQAAVLL 189

Query: 245 ESSK-EKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLG 303
           + S+  +   S     +LP F +PK + G TRIGDL+ QDM+KV  LALIELTAL D+LG
Sbjct: 190 QRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILG 249

Query: 304 IELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
           ++LK+ KA K K  ++ LF VPL +LLE D + +P  ++PL+ Q L+S +E+RGL+ EG+
Sbjct: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309

Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
           LR+PG+  R+K L Q+LE  FY G F+W+ V  +DA+ LLK FIR+LP PLL+ EYL AF
Sbjct: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369

Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
             V N+P  KQ+LQ L+LL+++LP+ NR+ LKALLEFL++V+  ++ NKMT+ NV+ VMA
Sbjct: 370 AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMA 429

Query: 484 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKK 543
           PNLF+      K  + +E  +A G A  + +++ YQ LLWT+  F+V QVRK N  + ++
Sbjct: 430 PNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRR 489

Query: 544 DK---RAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600
            +     +K  L++M  DR      DK+ +  +    V ++Q     K  + + LT   K
Sbjct: 490 PQLCDAGLKTWLRRMHADR------DKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTK 543

Query: 601 ASDVLARFLSQESGVA----------------QTLKKGEVFLYEIGGNIGERCLDDDTYM 644
            + VL +F    S  +                ++++   + LYE+GGNI E  LD D Y+
Sbjct: 544 VAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYL 603

Query: 645 KDLYQLNPNAEWVIKSKP 662
            DLY+ NP+ EWV+K  P
Sbjct: 604 LDLYRANPHGEWVLKQNP 621


>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score =  414 bits (1065), Expect = e-115
 Identities = 239/618 (38%), Positives = 365/618 (59%), Gaps = 45/618 (7%)

Query: 70  LDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESA-- 127
           ++  SM+ +W+E+E I++  E  +ED      + P+EGE E +WL++ GLS L G     
Sbjct: 24  VESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLD 83

Query: 128 GDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFA---QQRESKET 184
           GD QE    LSTLT+TQ AAV +R++  ++++R+++K   + DVRD+F      + S E 
Sbjct: 84  GDHQE---LLSTLTQTQVAAVCRRLDIYARSVRRQHKT-PVRDVRDVFGVFNSGKMSSEN 139

Query: 185 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK 244
              G +   L +  +K+    +              +E    E   N++ +++EQA    
Sbjct: 140 GDSGMKGAQLSSGASKFPPAAEPGGL----------QEQAGREEAFNMDSAYSEQAAVLL 189

Query: 245 ESSK-EKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLG 303
           + S+  +   S     +LP F +PK + G TRIGDL+ QDM+KV  LALIELTAL D+LG
Sbjct: 190 QRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILG 249

Query: 304 IELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
           ++LK+ KA K K  ++ LF VPL +LLE D + +P  ++PL+ Q L+S +E+RGL+ EG+
Sbjct: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309

Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
           LR+PG+  R+K L Q+LE  FY G F+W+ V  +DA+ LLK FIR+LP PLL+ EYL AF
Sbjct: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369

Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
             V N+P  KQ+LQ L+LL+++LP+ NR+ LKALLEFL++V+  ++ NKMT+ NV+ VMA
Sbjct: 370 AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMA 429

Query: 484 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKK 543
           PNLF+      K  + +E  +A G A  + +++ YQ LLWT+  F+V QVRK N  + ++
Sbjct: 430 PNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRR 489

Query: 544 DK---RAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600
            +     +K  L++M  DR      DK+ +  +    V ++Q     K  + + LT   K
Sbjct: 490 PQLCDAGLKTWLRRMHADR------DKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTK 543

Query: 601 ASDVLARFLSQESGVA----------------QTLKKGEVFLYEIGGNIGERCLDDDTYM 644
            + VL +F    S  +                ++++   + LYE+GGNI E  LD D Y+
Sbjct: 544 VAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYL 603

Query: 645 KDLYQLNPNAEWVIKSKP 662
            DLY+ NP+ EWV+K  P
Sbjct: 604 LDLYRANPHGEWVLKQNP 621


>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
           sapiens]
          Length = 622

 Score =  414 bits (1065), Expect = e-115
 Identities = 239/618 (38%), Positives = 365/618 (59%), Gaps = 45/618 (7%)

Query: 70  LDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESA-- 127
           ++  SM+ +W+E+E I++  E  +ED      + P+EGE E +WL++ GLS L G     
Sbjct: 24  VESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLD 83

Query: 128 GDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFA---QQRESKET 184
           GD QE    LSTLT+TQ AAV +R++  ++++R+++K   + DVRD+F      + S E 
Sbjct: 84  GDHQE---LLSTLTQTQVAAVCRRLDIYARSVRRQHKT-PVRDVRDVFGVFNSGKMSSEN 139

Query: 185 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK 244
              G +   L +  +K+    +              +E    E   N++ +++EQA    
Sbjct: 140 GDSGMKGAQLSSGASKFPPAAEPGGL----------QEQAGREEAFNMDSAYSEQAAVLL 189

Query: 245 ESSK-EKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLG 303
           + S+  +   S     +LP F +PK + G TRIGDL+ QDM+KV  LALIELTAL D+LG
Sbjct: 190 QRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILG 249

Query: 304 IELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
           ++LK+ KA K K  ++ LF VPL +LLE D + +P  ++PL+ Q L+S +E+RGL+ EG+
Sbjct: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309

Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
           LR+PG+  R+K L Q+LE  FY G F+W+ V  +DA+ LLK FIR+LP PLL+ EYL AF
Sbjct: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369

Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
             V N+P  KQ+LQ L+LL+++LP+ NR+ LKALLEFL++V+  ++ NKMT+ NV+ VMA
Sbjct: 370 AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMA 429

Query: 484 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKK 543
           PNLF+      K  + +E  +A G A  + +++ YQ LLWT+  F+V QVRK N  + ++
Sbjct: 430 PNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRR 489

Query: 544 DK---RAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600
            +     +K  L++M  DR      DK+ +  +    V ++Q     K  + + LT   K
Sbjct: 490 PQLCDAGLKTWLRRMHADR------DKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTK 543

Query: 601 ASDVLARFLSQESGVA----------------QTLKKGEVFLYEIGGNIGERCLDDDTYM 644
            + VL +F    S  +                ++++   + LYE+GGNI E  LD D Y+
Sbjct: 544 VAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYL 603

Query: 645 KDLYQLNPNAEWVIKSKP 662
            DLY+ NP+ EWV+K  P
Sbjct: 604 LDLYRANPHGEWVLKQNP 621


>gi|59710113 Rho GTPase activating protein 28 isoform a [Homo
           sapiens]
          Length = 570

 Score =  385 bits (989), Expect = e-107
 Identities = 204/457 (44%), Positives = 295/457 (64%), Gaps = 20/457 (4%)

Query: 215 EKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTT 274
           EK IPPE       +++ EVS++E      + +K K  + K +D  L  F + K + G T
Sbjct: 117 EKNIPPEAE-----ELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLT 171

Query: 275 RIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQ 334
             GDL+ +DMKK+ HL+LIELTA +D  GI+LK+ K  K+K +D+G+F VPLT LL+ D+
Sbjct: 172 EAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDR 231

Query: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394
           +K PG+++PL+ QK   ++EE GLE+EG+ R+ G   ++K   +EL+AKF    F W+ +
Sbjct: 232 KKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKM 291

Query: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDT 453
              +AA +LK F RELP  L  VEY+ AF   ++  P  K Q QAL+L+V+ LPDANRD 
Sbjct: 292 CHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDA 351

Query: 454 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMH 513
            +AL+ F  +VI N+ KN+M++ N++ VMAPNLF   +   K S+  E ++A   A+ + 
Sbjct: 352 AQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIR 408

Query: 514 LLIKYQKLLWTIPKFIVNQVRKQN--TENHKKDKRAMKKLLKKMAYDREK--------YE 563
           L++KYQK+LW +P F++ QVR+ N  T   KK   +++KLL++   +RE          +
Sbjct: 409 LMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQ 468

Query: 564 KQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQES-GVAQTLKKG 622
           K   +   +DVP+GVIRV AP LSKVSMAIQL  + KA D+LA+F  + S G ++ +K  
Sbjct: 469 KSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSSECIKIQ 528

Query: 623 EVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIK 659
              LYEIGGNIGE CLD D Y+ D+Y++NP AEWVIK
Sbjct: 529 NQRLYEIGGNIGEHCLDPDAYILDVYRINPQAEWVIK 565


>gi|59710111 Rho GTPase activating protein 28 isoform b [Homo
           sapiens]
          Length = 563

 Score =  332 bits (850), Expect = 9e-91
 Identities = 176/405 (43%), Positives = 259/405 (63%), Gaps = 19/405 (4%)

Query: 215 EKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTT 274
           EK IPPE       +++ EVS++E      + +K K  + K +D  L  F + K + G T
Sbjct: 117 EKNIPPEAE-----ELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLT 171

Query: 275 RIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQ 334
             GDL+ +DMKK+ HL+LIELTA +D  GI+LK+ K  K+K +D+G+F VPLT LL+ D+
Sbjct: 172 EAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDR 231

Query: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394
           +K PG+++PL+ QK   ++EE GLE+EG+ R+ G   ++K   +EL+AKF    F W+ +
Sbjct: 232 KKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKM 291

Query: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDT 453
              +AA +LK F RELP  L  VEY+ AF   ++  P  K Q QAL+L+V+ LPDANRD 
Sbjct: 292 CHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDA 351

Query: 454 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMH 513
            +AL+ F  +VI N+ KN+M++ N++ VMAPNLF   +   K S+  E ++A   A+ + 
Sbjct: 352 AQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIR 408

Query: 514 LLIKYQKLLWTIPKFIVNQVRKQN--TENHKKDKRAMKKLLKKMAYDREK--------YE 563
           L++KYQK+LW +P F++ QVR+ N  T   KK   +++KLL++   +RE          +
Sbjct: 409 LMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQ 468

Query: 564 KQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARF 608
           K   +   +DVP+GVIRV AP LSKVSMAIQL  + KA D+LA+F
Sbjct: 469 KSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKF 513


>gi|41281907 StAR-related lipid transfer (START) domain containing
           13 isoform beta [Homo sapiens]
          Length = 1105

 Score =  103 bits (257), Expect = 5e-22
 Identities = 95/370 (25%), Positives = 169/370 (45%), Gaps = 56/370 (15%)

Query: 206 DEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLP--- 262
           D   N V E +  P        +D+  +V+    +LN+ E    + ++  G  A+L    
Sbjct: 527 DFEGNSVSEGRTTP--------SDVERDVT----SLNESEPPGVRDRRDSGVGASLTRPN 574

Query: 263 ------SFRL---PKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQ----- 308
                 SF+L   P+    +  I       +  +   +L+ LTA+ +   +  K      
Sbjct: 575 RRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWS 634

Query: 309 ----QKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
                K +K+   KD  +F VPL   +++      G  +P   Q+ +  +    L+  GL
Sbjct: 635 VPKFMKRMKVPDYKDKAVFGVPLIVHVQRT-----GQPLPQSIQQALRYLRSNCLDQVGL 689

Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
            R  G   RI  L +++   F E   N+E    +D A ++K F R+LP+PL + +  + F
Sbjct: 690 FRKSGVKSRIHAL-RQMNENFPENV-NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETF 747

Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
             +    +K+Q+LQA+   ++LL D NR+ L+ LL FL  V++  E+N+MT MN+A+ +A
Sbjct: 748 LHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLA 807

Query: 484 PNLFMCHALGLKSSE---QREFVMA-----------AGTANTMHLLIKYQKLLWTIPKFI 529
           P+LF  + L  +SS    Q+++              A      H++++  + L+ +P  +
Sbjct: 808 PSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDR-LFEVPHEL 866

Query: 530 VNQVRKQNTE 539
           V Q R    E
Sbjct: 867 VAQSRNSYVE 876


>gi|16445031 StAR-related lipid transfer (START) domain containing
           13 isoform gamma [Homo sapiens]
          Length = 995

 Score =  103 bits (257), Expect = 5e-22
 Identities = 95/370 (25%), Positives = 169/370 (45%), Gaps = 56/370 (15%)

Query: 206 DEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLP--- 262
           D   N V E +  P        +D+  +V+    +LN+ E    + ++  G  A+L    
Sbjct: 417 DFEGNSVSEGRTTP--------SDVERDVT----SLNESEPPGVRDRRDSGVGASLTRPN 464

Query: 263 ------SFRL---PKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQ----- 308
                 SF+L   P+    +  I       +  +   +L+ LTA+ +   +  K      
Sbjct: 465 RRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWS 524

Query: 309 ----QKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
                K +K+   KD  +F VPL   +++      G  +P   Q+ +  +    L+  GL
Sbjct: 525 VPKFMKRMKVPDYKDKAVFGVPLIVHVQRT-----GQPLPQSIQQALRYLRSNCLDQVGL 579

Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
            R  G   RI  L +++   F E   N+E    +D A ++K F R+LP+PL + +  + F
Sbjct: 580 FRKSGVKSRIHAL-RQMNENFPENV-NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETF 637

Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
             +    +K+Q+LQA+   ++LL D NR+ L+ LL FL  V++  E+N+MT MN+A+ +A
Sbjct: 638 LHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLA 697

Query: 484 PNLFMCHALGLKSSE---QREFVMA-----------AGTANTMHLLIKYQKLLWTIPKFI 529
           P+LF  + L  +SS    Q+++              A      H++++  + L+ +P  +
Sbjct: 698 PSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDR-LFEVPHEL 756

Query: 530 VNQVRKQNTE 539
           V Q R    E
Sbjct: 757 VAQSRNSYVE 766


>gi|41281898 StAR-related lipid transfer (START) domain containing
           13 isoform alpha [Homo sapiens]
          Length = 1113

 Score =  103 bits (257), Expect = 5e-22
 Identities = 95/370 (25%), Positives = 169/370 (45%), Gaps = 56/370 (15%)

Query: 206 DEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLP--- 262
           D   N V E +  P        +D+  +V+    +LN+ E    + ++  G  A+L    
Sbjct: 535 DFEGNSVSEGRTTP--------SDVERDVT----SLNESEPPGVRDRRDSGVGASLTRPN 582

Query: 263 ------SFRL---PKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQ----- 308
                 SF+L   P+    +  I       +  +   +L+ LTA+ +   +  K      
Sbjct: 583 RRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWS 642

Query: 309 ----QKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
                K +K+   KD  +F VPL   +++      G  +P   Q+ +  +    L+  GL
Sbjct: 643 VPKFMKRMKVPDYKDKAVFGVPLIVHVQRT-----GQPLPQSIQQALRYLRSNCLDQVGL 697

Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
            R  G   RI  L +++   F E   N+E    +D A ++K F R+LP+PL + +  + F
Sbjct: 698 FRKSGVKSRIHAL-RQMNENFPENV-NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETF 755

Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
             +    +K+Q+LQA+   ++LL D NR+ L+ LL FL  V++  E+N+MT MN+A+ +A
Sbjct: 756 LHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLA 815

Query: 484 PNLFMCHALGLKSSE---QREFVMA-----------AGTANTMHLLIKYQKLLWTIPKFI 529
           P+LF  + L  +SS    Q+++              A      H++++  + L+ +P  +
Sbjct: 816 PSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDR-LFEVPHEL 874

Query: 530 VNQVRKQNTE 539
           V Q R    E
Sbjct: 875 VAQSRNSYVE 884


>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
          Length = 1528

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 8/195 (4%)

Query: 307  KQQKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLR 365
            K  K +K+   KD  +F VPLT  +++      G  +P   Q+ +  +    L+  GL R
Sbjct: 1060 KFMKRIKVPDYKDRSVFGVPLTVNVQRT-----GQPLPQSIQQAMRYLRNHCLDQVGLFR 1114

Query: 366  IPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQA 425
              G   RI+ L Q  E        N+E    +D A +LK + R+LP+PL++ +  + F  
Sbjct: 1115 KSGVKSRIQALRQMNEGAI--DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQ 1172

Query: 426  VQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPN 485
            +     K Q+LQA+   ++LLPD NR+ L+ LL FL  V    ++N+MT  N+A+ +AP+
Sbjct: 1173 IYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPS 1232

Query: 486  LFMCHALGLKSSEQR 500
            LF  + L  ++S  R
Sbjct: 1233 LFHLNTLKRENSSPR 1247


>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
          Length = 1091

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 8/195 (4%)

Query: 307 KQQKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLR 365
           K  K +K+   KD  +F VPLT  +++      G  +P   Q+ +  +    L+  GL R
Sbjct: 623 KFMKRIKVPDYKDRSVFGVPLTVNVQRT-----GQPLPQSIQQAMRYLRNHCLDQVGLFR 677

Query: 366 IPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQA 425
             G   RI+ L Q  E        N+E    +D A +LK + R+LP+PL++ +  + F  
Sbjct: 678 KSGVKSRIQALRQMNEGAI--DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQ 735

Query: 426 VQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPN 485
           +     K Q+LQA+   ++LLPD NR+ L+ LL FL  V    ++N+MT  N+A+ +AP+
Sbjct: 736 IYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPS 795

Query: 486 LFMCHALGLKSSEQR 500
           LF  + L  ++S  R
Sbjct: 796 LFHLNTLKRENSSPR 810


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 59/168 (35%), Positives = 90/168 (53%), Gaps = 9/168 (5%)

Query: 321 LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQEL 380
           +F   L AL E+++      R+P   Q+ I  +E RGL+ +GL RI G    I+ L  ++
Sbjct: 326 VFGCALAALCERERS-----RVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 380

Query: 381 E--AKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438
           +   +       WE V  H     LKLF RELP+PL    + + F A   L  + ++ + 
Sbjct: 381 DHDERLDLDDGRWEDV--HVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRC 438

Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
           +  LV  LP  N DTL+ L + L RVI++ E+N+M+V +VA+V  P L
Sbjct: 439 VRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 486


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
           sapiens]
          Length = 548

 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 59/168 (35%), Positives = 90/168 (53%), Gaps = 9/168 (5%)

Query: 321 LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQEL 380
           +F   L AL E+++      R+P   Q+ I  +E RGL+ +GL RI G    I+ L  ++
Sbjct: 353 VFGCALAALCERERS-----RVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 407

Query: 381 E--AKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438
           +   +       WE V  H     LKLF RELP+PL    + + F A   L  + ++ + 
Sbjct: 408 DHDERLDLDDGRWEDV--HVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRC 465

Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
           +  LV  LP  N DTL+ L + L RVI++ E+N+M+V +VA+V  P L
Sbjct: 466 VRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 513


>gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]
          Length = 494

 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 60/189 (31%), Positives = 102/189 (53%), Gaps = 23/189 (12%)

Query: 356 RGLETEGLLRIPGAAIRIKNLCQELEAKFYEGT-FNWESVKQH--DAASLLKLFIRELPQ 412
           + L  EGL R+PG ++R + L   L      GT  + ES + H  D A+LLK+F+ ELP+
Sbjct: 134 KNLRVEGLFRVPGNSVRQQILRDALN----NGTDIDLESGEFHSNDVATLLKMFLGELPE 189

Query: 413 PLLSVEYLKAFQAVQ------------NLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460
           PLL+ ++  A   +             N+P K +Q++AL LL ++LP  NR+ LK LL+ 
Sbjct: 190 PLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDL 249

Query: 461 LQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQK 520
           L +    ++KNKM+  N+A++ AP++     +     ++    + +G    M  +IK+ +
Sbjct: 250 LYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSG----MAFMIKHSQ 305

Query: 521 LLWTIPKFI 529
            L+  P +I
Sbjct: 306 KLFKAPAYI 314


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 67/200 (33%), Positives = 98/200 (49%), Gaps = 18/200 (9%)

Query: 334 QRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKF--YEGTFNW 391
           +RK      PL+ ++ +  I ERGL  EGL R+PG A    NL ++L+  F   E     
Sbjct: 164 ERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQA----NLVRDLQDSFDCGEKPLFD 219

Query: 392 ESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLL--VILLPDA 449
            +   H  ASLLKL++RELP+P++     + F +   L TK +    L L   V  LP A
Sbjct: 220 STTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQA 279

Query: 450 NRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509
           N + L+ + +FL  V      NKM+V N+A V  PN+       L+   +    +  GT+
Sbjct: 280 NYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNI-------LRPQVEDPVTIMEGTS 332

Query: 510 NTMHL---LIKYQKLLWTIP 526
              HL   LI+    L+T P
Sbjct: 333 LVQHLMTVLIRKHSQLFTAP 352


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 58/202 (28%), Positives = 100/202 (49%), Gaps = 2/202 (0%)

Query: 292 LIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLIS 351
           LIE+ A Y    + L Q    +IK +       P      ++   + G  I    +  ++
Sbjct: 218 LIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVT 277

Query: 352 RIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELP 411
            + E G++ EGL R+  +A ++K L   L+    +      S   H  A  LK ++RELP
Sbjct: 278 MLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD--VQEYSADPHAIAGALKSYLRELP 335

Query: 412 QPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKN 471
           +PL++ E    +    N+  + ++LQAL      LP AN + ++ L++FL ++ + ++ N
Sbjct: 336 EPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVN 395

Query: 472 KMTVMNVAMVMAPNLFMCHALG 493
           KMT  N+A+V+ PNL    A G
Sbjct: 396 KMTPSNMAIVLGPNLLWPQAEG 417


>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
          Length = 771

 Score = 86.7 bits (213), Expect = 6e-17
 Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%)

Query: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400
           ++P +       +E+ GL+T G+ R+  +  R++ L +E +           SV  HD A
Sbjct: 206 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 263

Query: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460
           +LLK F+R++P PLL+ E   AF     L   ++QL  L LL+ LLP  N DTL  LL+F
Sbjct: 264 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 322

Query: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509
           L  V     DN  K       NKMT +N+A +  PNL        KSS++   V ++  A
Sbjct: 323 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 378

Query: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533
                    +  +I+  + L+ +P  + N+V
Sbjct: 379 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 409


>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
           sapiens]
          Length = 765

 Score = 86.7 bits (213), Expect = 6e-17
 Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%)

Query: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400
           ++P +       +E+ GL+T G+ R+  +  R++ L +E +           SV  HD A
Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 466

Query: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460
           +LLK F+R++P PLL+ E   AF     L   ++QL  L LL+ LLP  N DTL  LL+F
Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525

Query: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509
           L  V     DN  K       NKMT +N+A +  PNL        KSS++   V ++  A
Sbjct: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 581

Query: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533
                    +  +I+  + L+ +P  + N+V
Sbjct: 582 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 612


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
           sapiens]
          Length = 974

 Score = 86.7 bits (213), Expect = 6e-17
 Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%)

Query: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400
           ++P +       +E+ GL+T G+ R+  +  R++ L +E +           SV  HD A
Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 466

Query: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460
           +LLK F+R++P PLL+ E   AF     L   ++QL  L LL+ LLP  N DTL  LL+F
Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525

Query: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509
           L  V     DN  K       NKMT +N+A +  PNL        KSS++   V ++  A
Sbjct: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 581

Query: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533
                    +  +I+  + L+ +P  + N+V
Sbjct: 582 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 612


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 86.3 bits (212), Expect = 8e-17
 Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 2/148 (1%)

Query: 342  IPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAAS 401
            +P++ +KL+  +E  GL TEGL R  GAA R + L Q L+          E+   H    
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD--PAAVKLENFPIHAITG 1769

Query: 402  LLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFL 461
            +LK ++RELP+PL++      F     LP K++QL A+  ++  LP+AN ++L+ L+  L
Sbjct: 1770 VLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHL 1829

Query: 462  QRVIDNKEKNKMTVMNVAMVMAPNLFMC 489
             +V   ++ N+M+   +A++ AP L  C
Sbjct: 1830 VKVALLEDVNRMSPGALAIIFAPCLLRC 1857


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 86.3 bits (212), Expect = 8e-17
 Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 2/148 (1%)

Query: 342  IPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAAS 401
            +P++ +KL+  +E  GL TEGL R  GAA R + L Q L+          E+   H    
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD--PAAVKLENFPIHAITG 1769

Query: 402  LLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFL 461
            +LK ++RELP+PL++      F     LP K++QL A+  ++  LP+AN ++L+ L+  L
Sbjct: 1770 VLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHL 1829

Query: 462  QRVIDNKEKNKMTVMNVAMVMAPNLFMC 489
             +V   ++ N+M+   +A++ AP L  C
Sbjct: 1830 VKVALLEDVNRMSPGALAIIFAPCLLRC 1857


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 50/148 (33%), Positives = 80/148 (54%), Gaps = 7/148 (4%)

Query: 342 IPLIFQKLISRIEERGLETEGLLRIPG--AAIRIKNLCQELEAKFYEGTFNWESVKQHDA 399
           +P   +  I  +EE GL+ +G+ R+ G  A I+        + K       WE +  H  
Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDI--HVI 726

Query: 400 ASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALL 458
              LK+F RELP+PL +  +   F  A++  P  +Q++ A+  L+  LP  N+DT++ L 
Sbjct: 727 TGALKMFFRELPEPLFTFNHFNDFVNAIKQEP--RQRVAAVKDLIRQLPKPNQDTMQILF 784

Query: 459 EFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
             L+RVI+N EKN+MT  ++A+V  P L
Sbjct: 785 RHLRRVIENGEKNRMTYQSIAIVFGPTL 812


>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
          Length = 1397

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 52/160 (32%), Positives = 83/160 (51%), Gaps = 5/160 (3%)

Query: 330 LEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTF 389
           LE+ Q      R+PLI       +E RGLE+ G+ R+PG    + +L ++L      G  
Sbjct: 813 LEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG--PGDI 870

Query: 390 NWESVKQHDA---ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILL 446
           N +  +  D    +SLLK F R+LP+PL + +    F     +   +++++ L  L+  L
Sbjct: 871 NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL 930

Query: 447 PDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
           P    +TLK L+  L+ + D+ EKNKM   N+A+V  P L
Sbjct: 931 PGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTL 970


>gi|5803145 ralA binding protein 1 [Homo sapiens]
          Length = 655

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 49/167 (29%), Positives = 95/167 (56%), Gaps = 6/167 (3%)

Query: 321 LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQEL 380
           +F +PL   +E+      G+R+P +F++ I  +E+ G++ EG+ R+ G    IK+   EL
Sbjct: 189 IFGIPLADAVERTMM-YDGIRLPAVFRECIDYVEKYGMKCEGIYRVSG----IKSKVDEL 243

Query: 381 EAKF-YEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQAL 439
           +A +  E + N E  + +  ASLLK ++R+LP+ LL+ E +  F+      T+ +++Q  
Sbjct: 244 KAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEF 303

Query: 440 NLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
             L+  LP+ N   +  L+  +  VI  + + KM + N+++V++P +
Sbjct: 304 QRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350


>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
           sapiens]
          Length = 731

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 53/169 (31%), Positives = 83/169 (49%), Gaps = 22/169 (13%)

Query: 339 GMRIPLIFQKLISRIEERGLETEGLLRIPG---AAIRIKNLCQELEAKFYEGTF------ 389
           G  +P   +  I+ +++RGL+ +G+ R+ G      +++ L     A   +G +      
Sbjct: 533 GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQP 592

Query: 390 -----------NWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438
                       W+ +  H     LKLF+RELPQPL+    L  F+A   L   +Q L  
Sbjct: 593 GQEGRLDLDSTEWDDI--HVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQ 650

Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLF 487
           +  L+  +P  N DTL+ LLE L RVI + +KN+MT  N+ +V  P LF
Sbjct: 651 IQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 699


>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
           sapiens]
          Length = 547

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 53/169 (31%), Positives = 83/169 (49%), Gaps = 22/169 (13%)

Query: 339 GMRIPLIFQKLISRIEERGLETEGLLRIPG---AAIRIKNLCQELEAKFYEGTF------ 389
           G  +P   +  I+ +++RGL+ +G+ R+ G      +++ L     A   +G +      
Sbjct: 349 GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQP 408

Query: 390 -----------NWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438
                       W+ +  H     LKLF+RELPQPL+    L  F+A   L   +Q L  
Sbjct: 409 GQEGRLDLDSTEWDDI--HVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQ 466

Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLF 487
           +  L+  +P  N DTL+ LLE L RVI + +KN+MT  N+ +V  P LF
Sbjct: 467 IQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 515


>gi|229094128 active breakpoint cluster region-related  protein
           isoform c [Homo sapiens]
          Length = 813

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 62/212 (29%), Positives = 104/212 (49%), Gaps = 9/212 (4%)

Query: 279 LAPQDMK-KVCHLALIELTALYDVLGIELKQQKAVKIKT---KDSGLFCVPLTALLEQDQ 334
           L PQ ++ K  H  +IE+  +     ++   +     +T   K +G+F V ++ + ++++
Sbjct: 552 LDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRER 611

Query: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394
            KVP      I ++ +  +E+RG+E  G+ RI G A  I+ L    +A   +       +
Sbjct: 612 SKVP-----YIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM 666

Query: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTL 454
             +  A  LKL+ RELP+PLL+     AF     L     +   +  L+  LPD N  T 
Sbjct: 667 DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITF 726

Query: 455 KALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
             LLE L+RV + +  NKM++ N+A V  P L
Sbjct: 727 LFLLEHLKRVAEKEPINKMSLHNLATVFGPTL 758


>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
           sapiens]
          Length = 653

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 21/243 (8%)

Query: 343 PLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEG---TFNWESVKQHDA 399
           P++ ++ +  I +RGL+ EGL R+PG A    NL +EL+  F  G   +F+  +   H  
Sbjct: 58  PMLVEQCVDFIRQRGLKEEGLFRLPGQA----NLVKELQDAFDCGEKPSFD-SNTDVHTV 112

Query: 400 ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQ--LQALNLLVILLPDANRDTLKAL 457
           ASLLKL++RELP+P++     + F +   L +K+++  ++ L   V  LP  N + LK +
Sbjct: 113 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 172

Query: 458 LEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLL-I 516
             FL  V      NKM+V N+A V  PN+       L+   +    +  GT     L+ +
Sbjct: 173 CRFLDEVQSYSGVNKMSVQNLATVFGPNI-------LRPKVEDPLTIMEGTVVVQQLMSV 225

Query: 517 KYQKLLWTIPKFIVNQVRKQ---NTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTNDAD 573
              K     PK    Q + Q   +  N  + K  M +L  K   + +    +  S + ++
Sbjct: 226 MISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSE 285

Query: 574 VPQ 576
            PQ
Sbjct: 286 SPQ 288


>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
           sapiens]
          Length = 655

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 21/243 (8%)

Query: 343 PLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEG---TFNWESVKQHDA 399
           P++ ++ +  I +RGL+ EGL R+PG A    NL +EL+  F  G   +F+  +   H  
Sbjct: 60  PMLVEQCVDFIRQRGLKEEGLFRLPGQA----NLVKELQDAFDCGEKPSFD-SNTDVHTV 114

Query: 400 ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQ--LQALNLLVILLPDANRDTLKAL 457
           ASLLKL++RELP+P++     + F +   L +K+++  ++ L   V  LP  N + LK +
Sbjct: 115 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 174

Query: 458 LEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLL-I 516
             FL  V      NKM+V N+A V  PN+       L+   +    +  GT     L+ +
Sbjct: 175 CRFLDEVQSYSGVNKMSVQNLATVFGPNI-------LRPKVEDPLTIMEGTVVVQQLMSV 227

Query: 517 KYQKLLWTIPKFIVNQVRKQ---NTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTNDAD 573
              K     PK    Q + Q   +  N  + K  M +L  K   + +    +  S + ++
Sbjct: 228 MISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSE 287

Query: 574 VPQ 576
            PQ
Sbjct: 288 SPQ 290


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
           sapiens]
          Length = 748

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 21/243 (8%)

Query: 343 PLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEG---TFNWESVKQHDA 399
           P++ ++ +  I +RGL+ EGL R+PG A    NL +EL+  F  G   +F+  +   H  
Sbjct: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQA----NLVKELQDAFDCGEKPSFD-SNTDVHTV 207

Query: 400 ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQ--LQALNLLVILLPDANRDTLKAL 457
           ASLLKL++RELP+P++     + F +   L +K+++  ++ L   V  LP  N + LK +
Sbjct: 208 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 267

Query: 458 LEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLL-I 516
             FL  V      NKM+V N+A V  PN+       L+   +    +  GT     L+ +
Sbjct: 268 CRFLDEVQSYSGVNKMSVQNLATVFGPNI-------LRPKVEDPLTIMEGTVVVQQLMSV 320

Query: 517 KYQKLLWTIPKFIVNQVRKQ---NTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTNDAD 573
              K     PK    Q + Q   +  N  + K  M +L  K   + +    +  S + ++
Sbjct: 321 MISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSE 380

Query: 574 VPQ 576
            PQ
Sbjct: 381 SPQ 383


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,488,518
Number of Sequences: 37866
Number of extensions: 1018187
Number of successful extensions: 3915
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 3570
Number of HSP's gapped (non-prelim): 364
length of query: 663
length of database: 18,247,518
effective HSP length: 109
effective length of query: 554
effective length of database: 14,120,124
effective search space: 7822548696
effective search space used: 7822548696
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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