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Search of human proteins with 39932589
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
(663 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] 1297 0.0
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom... 414 e-115
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom... 414 e-115
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H... 414 e-115
gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap... 385 e-107
gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap... 332 9e-91
gi|41281907 StAR-related lipid transfer (START) domain containin... 103 5e-22
gi|16445031 StAR-related lipid transfer (START) domain containin... 103 5e-22
gi|41281898 StAR-related lipid transfer (START) domain containin... 103 5e-22
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] 99 1e-20
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] 99 1e-20
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 91 4e-18
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 91 4e-18
gi|67906814 Rho GTPase activating protein 19 [Homo sapiens] 90 6e-18
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 87 5e-17
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 87 5e-17
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 87 6e-17
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 87 6e-17
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 87 6e-17
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 86 8e-17
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 86 8e-17
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 85 2e-16
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 84 3e-16
gi|5803145 ralA binding protein 1 [Homo sapiens] 84 3e-16
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 82 2e-15
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 82 2e-15
gi|229094128 active breakpoint cluster region-related protein i... 81 3e-15
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 81 3e-15
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 81 3e-15
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 81 3e-15
>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
Length = 663
Score = 1297 bits (3357), Expect = 0.0
Identities = 663/663 (100%), Positives = 663/663 (100%)
Query: 1 MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP 60
MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP
Sbjct: 1 MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPP 60
Query: 61 FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS 120
FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS
Sbjct: 61 FDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLS 120
Query: 121 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE 180
NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE
Sbjct: 121 NLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRE 180
Query: 181 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA 240
SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA
Sbjct: 181 SKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQA 240
Query: 241 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD 300
LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD
Sbjct: 241 LNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYD 300
Query: 301 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET 360
VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET
Sbjct: 301 VLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLET 360
Query: 361 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL 420
EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL
Sbjct: 361 EGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYL 420
Query: 421 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM 480
KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM
Sbjct: 421 KAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAM 480
Query: 481 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN 540
VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN
Sbjct: 481 VMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTEN 540
Query: 541 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600
HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK
Sbjct: 541 HKKDKRAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600
Query: 601 ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS 660
ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS
Sbjct: 601 ASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIKS 660
Query: 661 KPL 663
KPL
Sbjct: 661 KPL 663
>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 414 bits (1065), Expect = e-115
Identities = 239/618 (38%), Positives = 365/618 (59%), Gaps = 45/618 (7%)
Query: 70 LDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESA-- 127
++ SM+ +W+E+E I++ E +ED + P+EGE E +WL++ GLS L G
Sbjct: 24 VESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLD 83
Query: 128 GDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFA---QQRESKET 184
GD QE LSTLT+TQ AAV +R++ ++++R+++K + DVRD+F + S E
Sbjct: 84 GDHQE---LLSTLTQTQVAAVCRRLDIYARSVRRQHKT-PVRDVRDVFGVFNSGKMSSEN 139
Query: 185 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK 244
G + L + +K+ + +E E N++ +++EQA
Sbjct: 140 GDSGMKGAQLSSGASKFPPAAEPGGL----------QEQAGREEAFNMDSAYSEQAAVLL 189
Query: 245 ESSK-EKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLG 303
+ S+ + S +LP F +PK + G TRIGDL+ QDM+KV LALIELTAL D+LG
Sbjct: 190 QRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILG 249
Query: 304 IELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
++LK+ KA K K ++ LF VPL +LLE D + +P ++PL+ Q L+S +E+RGL+ EG+
Sbjct: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309
Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
LR+PG+ R+K L Q+LE FY G F+W+ V +DA+ LLK FIR+LP PLL+ EYL AF
Sbjct: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369
Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
V N+P KQ+LQ L+LL+++LP+ NR+ LKALLEFL++V+ ++ NKMT+ NV+ VMA
Sbjct: 370 AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMA 429
Query: 484 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKK 543
PNLF+ K + +E +A G A + +++ YQ LLWT+ F+V QVRK N + ++
Sbjct: 430 PNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRR 489
Query: 544 DK---RAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600
+ +K L++M DR DK+ + + V ++Q K + + LT K
Sbjct: 490 PQLCDAGLKTWLRRMHADR------DKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTK 543
Query: 601 ASDVLARFLSQESGVA----------------QTLKKGEVFLYEIGGNIGERCLDDDTYM 644
+ VL +F S + ++++ + LYE+GGNI E LD D Y+
Sbjct: 544 VAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYL 603
Query: 645 KDLYQLNPNAEWVIKSKP 662
DLY+ NP+ EWV+K P
Sbjct: 604 LDLYRANPHGEWVLKQNP 621
>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 414 bits (1065), Expect = e-115
Identities = 239/618 (38%), Positives = 365/618 (59%), Gaps = 45/618 (7%)
Query: 70 LDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESA-- 127
++ SM+ +W+E+E I++ E +ED + P+EGE E +WL++ GLS L G
Sbjct: 24 VESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLD 83
Query: 128 GDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFA---QQRESKET 184
GD QE LSTLT+TQ AAV +R++ ++++R+++K + DVRD+F + S E
Sbjct: 84 GDHQE---LLSTLTQTQVAAVCRRLDIYARSVRRQHKT-PVRDVRDVFGVFNSGKMSSEN 139
Query: 185 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK 244
G + L + +K+ + +E E N++ +++EQA
Sbjct: 140 GDSGMKGAQLSSGASKFPPAAEPGGL----------QEQAGREEAFNMDSAYSEQAAVLL 189
Query: 245 ESSK-EKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLG 303
+ S+ + S +LP F +PK + G TRIGDL+ QDM+KV LALIELTAL D+LG
Sbjct: 190 QRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILG 249
Query: 304 IELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
++LK+ KA K K ++ LF VPL +LLE D + +P ++PL+ Q L+S +E+RGL+ EG+
Sbjct: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309
Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
LR+PG+ R+K L Q+LE FY G F+W+ V +DA+ LLK FIR+LP PLL+ EYL AF
Sbjct: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369
Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
V N+P KQ+LQ L+LL+++LP+ NR+ LKALLEFL++V+ ++ NKMT+ NV+ VMA
Sbjct: 370 AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMA 429
Query: 484 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKK 543
PNLF+ K + +E +A G A + +++ YQ LLWT+ F+V QVRK N + ++
Sbjct: 430 PNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRR 489
Query: 544 DK---RAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600
+ +K L++M DR DK+ + + V ++Q K + + LT K
Sbjct: 490 PQLCDAGLKTWLRRMHADR------DKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTK 543
Query: 601 ASDVLARFLSQESGVA----------------QTLKKGEVFLYEIGGNIGERCLDDDTYM 644
+ VL +F S + ++++ + LYE+GGNI E LD D Y+
Sbjct: 544 VAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYL 603
Query: 645 KDLYQLNPNAEWVIKSKP 662
DLY+ NP+ EWV+K P
Sbjct: 604 LDLYRANPHGEWVLKQNP 621
>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
sapiens]
Length = 622
Score = 414 bits (1065), Expect = e-115
Identities = 239/618 (38%), Positives = 365/618 (59%), Gaps = 45/618 (7%)
Query: 70 LDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESA-- 127
++ SM+ +W+E+E I++ E +ED + P+EGE E +WL++ GLS L G
Sbjct: 24 VESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLD 83
Query: 128 GDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFA---QQRESKET 184
GD QE LSTLT+TQ AAV +R++ ++++R+++K + DVRD+F + S E
Sbjct: 84 GDHQE---LLSTLTQTQVAAVCRRLDIYARSVRRQHKT-PVRDVRDVFGVFNSGKMSSEN 139
Query: 185 APGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQK 244
G + L + +K+ + +E E N++ +++EQA
Sbjct: 140 GDSGMKGAQLSSGASKFPPAAEPGGL----------QEQAGREEAFNMDSAYSEQAAVLL 189
Query: 245 ESSK-EKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLG 303
+ S+ + S +LP F +PK + G TRIGDL+ QDM+KV LALIELTAL D+LG
Sbjct: 190 QRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILG 249
Query: 304 IELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
++LK+ KA K K ++ LF VPL +LLE D + +P ++PL+ Q L+S +E+RGL+ EG+
Sbjct: 250 LDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGI 309
Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
LR+PG+ R+K L Q+LE FY G F+W+ V +DA+ LLK FIR+LP PLL+ EYL AF
Sbjct: 310 LRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAF 369
Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
V N+P KQ+LQ L+LL+++LP+ NR+ LKALLEFL++V+ ++ NKMT+ NV+ VMA
Sbjct: 370 AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMA 429
Query: 484 PNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQKLLWTIPKFIVNQVRKQNTENHKK 543
PNLF+ K + +E +A G A + +++ YQ LLWT+ F+V QVRK N + ++
Sbjct: 430 PNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRR 489
Query: 544 DK---RAMKKLLKKMAYDREKYEKQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELK 600
+ +K L++M DR DK+ + + V ++Q K + + LT K
Sbjct: 490 PQLCDAGLKTWLRRMHADR------DKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTK 543
Query: 601 ASDVLARFLSQESGVA----------------QTLKKGEVFLYEIGGNIGERCLDDDTYM 644
+ VL +F S + ++++ + LYE+GGNI E LD D Y+
Sbjct: 544 VAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYL 603
Query: 645 KDLYQLNPNAEWVIKSKP 662
DLY+ NP+ EWV+K P
Sbjct: 604 LDLYRANPHGEWVLKQNP 621
>gi|59710113 Rho GTPase activating protein 28 isoform a [Homo
sapiens]
Length = 570
Score = 385 bits (989), Expect = e-107
Identities = 204/457 (44%), Positives = 295/457 (64%), Gaps = 20/457 (4%)
Query: 215 EKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTT 274
EK IPPE +++ EVS++E + +K K + K +D L F + K + G T
Sbjct: 117 EKNIPPEAE-----ELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLT 171
Query: 275 RIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQ 334
GDL+ +DMKK+ HL+LIELTA +D GI+LK+ K K+K +D+G+F VPLT LL+ D+
Sbjct: 172 EAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDR 231
Query: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394
+K PG+++PL+ QK ++EE GLE+EG+ R+ G ++K +EL+AKF F W+ +
Sbjct: 232 KKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKM 291
Query: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDT 453
+AA +LK F RELP L VEY+ AF ++ P K Q QAL+L+V+ LPDANRD
Sbjct: 292 CHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDA 351
Query: 454 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMH 513
+AL+ F +VI N+ KN+M++ N++ VMAPNLF + K S+ E ++A A+ +
Sbjct: 352 AQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIR 408
Query: 514 LLIKYQKLLWTIPKFIVNQVRKQN--TENHKKDKRAMKKLLKKMAYDREK--------YE 563
L++KYQK+LW +P F++ QVR+ N T KK +++KLL++ +RE +
Sbjct: 409 LMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQ 468
Query: 564 KQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQES-GVAQTLKKG 622
K + +DVP+GVIRV AP LSKVSMAIQL + KA D+LA+F + S G ++ +K
Sbjct: 469 KSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSSECIKIQ 528
Query: 623 EVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIK 659
LYEIGGNIGE CLD D Y+ D+Y++NP AEWVIK
Sbjct: 529 NQRLYEIGGNIGEHCLDPDAYILDVYRINPQAEWVIK 565
>gi|59710111 Rho GTPase activating protein 28 isoform b [Homo
sapiens]
Length = 563
Score = 332 bits (850), Expect = 9e-91
Identities = 176/405 (43%), Positives = 259/405 (63%), Gaps = 19/405 (4%)
Query: 215 EKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTT 274
EK IPPE +++ EVS++E + +K K + K +D L F + K + G T
Sbjct: 117 EKNIPPEAE-----ELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLT 171
Query: 275 RIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQ 334
GDL+ +DMKK+ HL+LIELTA +D GI+LK+ K K+K +D+G+F VPLT LL+ D+
Sbjct: 172 EAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDR 231
Query: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394
+K PG+++PL+ QK ++EE GLE+EG+ R+ G ++K +EL+AKF F W+ +
Sbjct: 232 KKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKM 291
Query: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDT 453
+AA +LK F RELP L VEY+ AF ++ P K Q QAL+L+V+ LPDANRD
Sbjct: 292 CHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDA 351
Query: 454 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMH 513
+AL+ F +VI N+ KN+M++ N++ VMAPNLF + K S+ E ++A A+ +
Sbjct: 352 AQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIR 408
Query: 514 LLIKYQKLLWTIPKFIVNQVRKQN--TENHKKDKRAMKKLLKKMAYDREK--------YE 563
L++KYQK+LW +P F++ QVR+ N T KK +++KLL++ +RE +
Sbjct: 409 LMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQ 468
Query: 564 KQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARF 608
K + +DVP+GVIRV AP LSKVSMAIQL + KA D+LA+F
Sbjct: 469 KSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKF 513
>gi|41281907 StAR-related lipid transfer (START) domain containing
13 isoform beta [Homo sapiens]
Length = 1105
Score = 103 bits (257), Expect = 5e-22
Identities = 95/370 (25%), Positives = 169/370 (45%), Gaps = 56/370 (15%)
Query: 206 DEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLP--- 262
D N V E + P +D+ +V+ +LN+ E + ++ G A+L
Sbjct: 527 DFEGNSVSEGRTTP--------SDVERDVT----SLNESEPPGVRDRRDSGVGASLTRPN 574
Query: 263 ------SFRL---PKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQ----- 308
SF+L P+ + I + + +L+ LTA+ + + K
Sbjct: 575 RRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWS 634
Query: 309 ----QKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
K +K+ KD +F VPL +++ G +P Q+ + + L+ GL
Sbjct: 635 VPKFMKRMKVPDYKDKAVFGVPLIVHVQRT-----GQPLPQSIQQALRYLRSNCLDQVGL 689
Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
R G RI L +++ F E N+E +D A ++K F R+LP+PL + + + F
Sbjct: 690 FRKSGVKSRIHAL-RQMNENFPENV-NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETF 747
Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
+ +K+Q+LQA+ ++LL D NR+ L+ LL FL V++ E+N+MT MN+A+ +A
Sbjct: 748 LHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLA 807
Query: 484 PNLFMCHALGLKSSE---QREFVMA-----------AGTANTMHLLIKYQKLLWTIPKFI 529
P+LF + L +SS Q+++ A H++++ + L+ +P +
Sbjct: 808 PSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDR-LFEVPHEL 866
Query: 530 VNQVRKQNTE 539
V Q R E
Sbjct: 867 VAQSRNSYVE 876
>gi|16445031 StAR-related lipid transfer (START) domain containing
13 isoform gamma [Homo sapiens]
Length = 995
Score = 103 bits (257), Expect = 5e-22
Identities = 95/370 (25%), Positives = 169/370 (45%), Gaps = 56/370 (15%)
Query: 206 DEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLP--- 262
D N V E + P +D+ +V+ +LN+ E + ++ G A+L
Sbjct: 417 DFEGNSVSEGRTTP--------SDVERDVT----SLNESEPPGVRDRRDSGVGASLTRPN 464
Query: 263 ------SFRL---PKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQ----- 308
SF+L P+ + I + + +L+ LTA+ + + K
Sbjct: 465 RRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWS 524
Query: 309 ----QKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
K +K+ KD +F VPL +++ G +P Q+ + + L+ GL
Sbjct: 525 VPKFMKRMKVPDYKDKAVFGVPLIVHVQRT-----GQPLPQSIQQALRYLRSNCLDQVGL 579
Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
R G RI L +++ F E N+E +D A ++K F R+LP+PL + + + F
Sbjct: 580 FRKSGVKSRIHAL-RQMNENFPENV-NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETF 637
Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
+ +K+Q+LQA+ ++LL D NR+ L+ LL FL V++ E+N+MT MN+A+ +A
Sbjct: 638 LHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLA 697
Query: 484 PNLFMCHALGLKSSE---QREFVMA-----------AGTANTMHLLIKYQKLLWTIPKFI 529
P+LF + L +SS Q+++ A H++++ + L+ +P +
Sbjct: 698 PSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDR-LFEVPHEL 756
Query: 530 VNQVRKQNTE 539
V Q R E
Sbjct: 757 VAQSRNSYVE 766
>gi|41281898 StAR-related lipid transfer (START) domain containing
13 isoform alpha [Homo sapiens]
Length = 1113
Score = 103 bits (257), Expect = 5e-22
Identities = 95/370 (25%), Positives = 169/370 (45%), Gaps = 56/370 (15%)
Query: 206 DEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLP--- 262
D N V E + P +D+ +V+ +LN+ E + ++ G A+L
Sbjct: 535 DFEGNSVSEGRTTP--------SDVERDVT----SLNESEPPGVRDRRDSGVGASLTRPN 582
Query: 263 ------SFRL---PKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQ----- 308
SF+L P+ + I + + +L+ LTA+ + + K
Sbjct: 583 RRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWS 642
Query: 309 ----QKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGL 363
K +K+ KD +F VPL +++ G +P Q+ + + L+ GL
Sbjct: 643 VPKFMKRMKVPDYKDKAVFGVPLIVHVQRT-----GQPLPQSIQQALRYLRSNCLDQVGL 697
Query: 364 LRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAF 423
R G RI L +++ F E N+E +D A ++K F R+LP+PL + + + F
Sbjct: 698 FRKSGVKSRIHAL-RQMNENFPENV-NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETF 755
Query: 424 QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMA 483
+ +K+Q+LQA+ ++LL D NR+ L+ LL FL V++ E+N+MT MN+A+ +A
Sbjct: 756 LHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLA 815
Query: 484 PNLFMCHALGLKSSE---QREFVMA-----------AGTANTMHLLIKYQKLLWTIPKFI 529
P+LF + L +SS Q+++ A H++++ + L+ +P +
Sbjct: 816 PSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDR-LFEVPHEL 874
Query: 530 VNQVRKQNTE 539
V Q R E
Sbjct: 875 VAQSRNSYVE 884
>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
Length = 1528
Score = 99.4 bits (246), Expect = 1e-20
Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 8/195 (4%)
Query: 307 KQQKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLR 365
K K +K+ KD +F VPLT +++ G +P Q+ + + L+ GL R
Sbjct: 1060 KFMKRIKVPDYKDRSVFGVPLTVNVQRT-----GQPLPQSIQQAMRYLRNHCLDQVGLFR 1114
Query: 366 IPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQA 425
G RI+ L Q E N+E +D A +LK + R+LP+PL++ + + F
Sbjct: 1115 KSGVKSRIQALRQMNEGAI--DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQ 1172
Query: 426 VQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPN 485
+ K Q+LQA+ ++LLPD NR+ L+ LL FL V ++N+MT N+A+ +AP+
Sbjct: 1173 IYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPS 1232
Query: 486 LFMCHALGLKSSEQR 500
LF + L ++S R
Sbjct: 1233 LFHLNTLKRENSSPR 1247
>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
Length = 1091
Score = 99.4 bits (246), Expect = 1e-20
Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 8/195 (4%)
Query: 307 KQQKAVKIKT-KDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLR 365
K K +K+ KD +F VPLT +++ G +P Q+ + + L+ GL R
Sbjct: 623 KFMKRIKVPDYKDRSVFGVPLTVNVQRT-----GQPLPQSIQQAMRYLRNHCLDQVGLFR 677
Query: 366 IPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQA 425
G RI+ L Q E N+E +D A +LK + R+LP+PL++ + + F
Sbjct: 678 KSGVKSRIQALRQMNEGAI--DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQ 735
Query: 426 VQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPN 485
+ K Q+LQA+ ++LLPD NR+ L+ LL FL V ++N+MT N+A+ +AP+
Sbjct: 736 IYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPS 795
Query: 486 LFMCHALGLKSSEQR 500
LF + L ++S R
Sbjct: 796 LFHLNTLKRENSSPR 810
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 90.5 bits (223), Expect = 4e-18
Identities = 59/168 (35%), Positives = 90/168 (53%), Gaps = 9/168 (5%)
Query: 321 LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQEL 380
+F L AL E+++ R+P Q+ I +E RGL+ +GL RI G I+ L ++
Sbjct: 326 VFGCALAALCERERS-----RVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 380
Query: 381 E--AKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438
+ + WE V H LKLF RELP+PL + + F A L + ++ +
Sbjct: 381 DHDERLDLDDGRWEDV--HVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRC 438
Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
+ LV LP N DTL+ L + L RVI++ E+N+M+V +VA+V P L
Sbjct: 439 VRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 486
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 90.5 bits (223), Expect = 4e-18
Identities = 59/168 (35%), Positives = 90/168 (53%), Gaps = 9/168 (5%)
Query: 321 LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQEL 380
+F L AL E+++ R+P Q+ I +E RGL+ +GL RI G I+ L ++
Sbjct: 353 VFGCALAALCERERS-----RVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 407
Query: 381 E--AKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438
+ + WE V H LKLF RELP+PL + + F A L + ++ +
Sbjct: 408 DHDERLDLDDGRWEDV--HVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRC 465
Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
+ LV LP N DTL+ L + L RVI++ E+N+M+V +VA+V P L
Sbjct: 466 VRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 513
>gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]
Length = 494
Score = 90.1 bits (222), Expect = 6e-18
Identities = 60/189 (31%), Positives = 102/189 (53%), Gaps = 23/189 (12%)
Query: 356 RGLETEGLLRIPGAAIRIKNLCQELEAKFYEGT-FNWESVKQH--DAASLLKLFIRELPQ 412
+ L EGL R+PG ++R + L L GT + ES + H D A+LLK+F+ ELP+
Sbjct: 134 KNLRVEGLFRVPGNSVRQQILRDALN----NGTDIDLESGEFHSNDVATLLKMFLGELPE 189
Query: 413 PLLSVEYLKAFQAVQ------------NLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460
PLL+ ++ A + N+P K +Q++AL LL ++LP NR+ LK LL+
Sbjct: 190 PLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDL 249
Query: 461 LQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQK 520
L + ++KNKM+ N+A++ AP++ + ++ + +G M +IK+ +
Sbjct: 250 LYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSG----MAFMIKHSQ 305
Query: 521 LLWTIPKFI 529
L+ P +I
Sbjct: 306 KLFKAPAYI 314
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 87.0 bits (214), Expect = 5e-17
Identities = 67/200 (33%), Positives = 98/200 (49%), Gaps = 18/200 (9%)
Query: 334 QRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKF--YEGTFNW 391
+RK PL+ ++ + I ERGL EGL R+PG A NL ++L+ F E
Sbjct: 164 ERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQA----NLVRDLQDSFDCGEKPLFD 219
Query: 392 ESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLL--VILLPDA 449
+ H ASLLKL++RELP+P++ + F + L TK + L L V LP A
Sbjct: 220 STTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQA 279
Query: 450 NRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509
N + L+ + +FL V NKM+V N+A V PN+ L+ + + GT+
Sbjct: 280 NYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNI-------LRPQVEDPVTIMEGTS 332
Query: 510 NTMHL---LIKYQKLLWTIP 526
HL LI+ L+T P
Sbjct: 333 LVQHLMTVLIRKHSQLFTAP 352
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 87.0 bits (214), Expect = 5e-17
Identities = 58/202 (28%), Positives = 100/202 (49%), Gaps = 2/202 (0%)
Query: 292 LIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLIFQKLIS 351
LIE+ A Y + L Q +IK + P ++ + G I + ++
Sbjct: 218 LIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVT 277
Query: 352 RIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELP 411
+ E G++ EGL R+ +A ++K L L+ + S H A LK ++RELP
Sbjct: 278 MLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD--VQEYSADPHAIAGALKSYLRELP 335
Query: 412 QPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKN 471
+PL++ E + N+ + ++LQAL LP AN + ++ L++FL ++ + ++ N
Sbjct: 336 EPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVN 395
Query: 472 KMTVMNVAMVMAPNLFMCHALG 493
KMT N+A+V+ PNL A G
Sbjct: 396 KMTPSNMAIVLGPNLLWPQAEG 417
>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
Length = 771
Score = 86.7 bits (213), Expect = 6e-17
Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%)
Query: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400
++P + +E+ GL+T G+ R+ + R++ L +E + SV HD A
Sbjct: 206 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 263
Query: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460
+LLK F+R++P PLL+ E AF L ++QL L LL+ LLP N DTL LL+F
Sbjct: 264 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 322
Query: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509
L V DN K NKMT +N+A + PNL KSS++ V ++ A
Sbjct: 323 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 378
Query: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533
+ +I+ + L+ +P + N+V
Sbjct: 379 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 409
>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
sapiens]
Length = 765
Score = 86.7 bits (213), Expect = 6e-17
Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%)
Query: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400
++P + +E+ GL+T G+ R+ + R++ L +E + SV HD A
Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 466
Query: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460
+LLK F+R++P PLL+ E AF L ++QL L LL+ LLP N DTL LL+F
Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
Query: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509
L V DN K NKMT +N+A + PNL KSS++ V ++ A
Sbjct: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 581
Query: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533
+ +I+ + L+ +P + N+V
Sbjct: 582 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 612
>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
sapiens]
Length = 974
Score = 86.7 bits (213), Expect = 6e-17
Identities = 67/211 (31%), Positives = 104/211 (49%), Gaps = 25/211 (11%)
Query: 341 RIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAA 400
++P + +E+ GL+T G+ R+ + R++ L +E + SV HD A
Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSV--HDVA 466
Query: 401 SLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460
+LLK F+R++P PLL+ E AF L ++QL L LL+ LLP N DTL LL+F
Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTL-LLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF 525
Query: 461 LQRVI----DNKEK-------NKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTA 509
L V DN K NKMT +N+A + PNL KSS++ V ++ A
Sbjct: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ----KSSDKEFSVQSSARA 581
Query: 510 N-------TMHLLIKYQKLLWTIPKFIVNQV 533
+ +I+ + L+ +P + N+V
Sbjct: 582 EESTAIIAVVQKMIENYEALFMVPPDLQNEV 612
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 86.3 bits (212), Expect = 8e-17
Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 2/148 (1%)
Query: 342 IPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAAS 401
+P++ +KL+ +E GL TEGL R GAA R + L Q L+ E+ H
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD--PAAVKLENFPIHAITG 1769
Query: 402 LLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFL 461
+LK ++RELP+PL++ F LP K++QL A+ ++ LP+AN ++L+ L+ L
Sbjct: 1770 VLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHL 1829
Query: 462 QRVIDNKEKNKMTVMNVAMVMAPNLFMC 489
+V ++ N+M+ +A++ AP L C
Sbjct: 1830 VKVALLEDVNRMSPGALAIIFAPCLLRC 1857
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 86.3 bits (212), Expect = 8e-17
Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 2/148 (1%)
Query: 342 IPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAAS 401
+P++ +KL+ +E GL TEGL R GAA R + L Q L+ E+ H
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD--PAAVKLENFPIHAITG 1769
Query: 402 LLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFL 461
+LK ++RELP+PL++ F LP K++QL A+ ++ LP+AN ++L+ L+ L
Sbjct: 1770 VLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHL 1829
Query: 462 QRVIDNKEKNKMTVMNVAMVMAPNLFMC 489
+V ++ N+M+ +A++ AP L C
Sbjct: 1830 VKVALLEDVNRMSPGALAIIFAPCLLRC 1857
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 85.1 bits (209), Expect = 2e-16
Identities = 50/148 (33%), Positives = 80/148 (54%), Gaps = 7/148 (4%)
Query: 342 IPLIFQKLISRIEERGLETEGLLRIPG--AAIRIKNLCQELEAKFYEGTFNWESVKQHDA 399
+P + I +EE GL+ +G+ R+ G A I+ + K WE + H
Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDI--HVI 726
Query: 400 ASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDTLKALL 458
LK+F RELP+PL + + F A++ P +Q++ A+ L+ LP N+DT++ L
Sbjct: 727 TGALKMFFRELPEPLFTFNHFNDFVNAIKQEP--RQRVAAVKDLIRQLPKPNQDTMQILF 784
Query: 459 EFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
L+RVI+N EKN+MT ++A+V P L
Sbjct: 785 RHLRRVIENGEKNRMTYQSIAIVFGPTL 812
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 84.3 bits (207), Expect = 3e-16
Identities = 52/160 (32%), Positives = 83/160 (51%), Gaps = 5/160 (3%)
Query: 330 LEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTF 389
LE+ Q R+PLI +E RGLE+ G+ R+PG + +L ++L G
Sbjct: 813 LEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG--PGDI 870
Query: 390 NWESVKQHDA---ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILL 446
N + + D +SLLK F R+LP+PL + + F + +++++ L L+ L
Sbjct: 871 NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL 930
Query: 447 PDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
P +TLK L+ L+ + D+ EKNKM N+A+V P L
Sbjct: 931 PGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTL 970
>gi|5803145 ralA binding protein 1 [Homo sapiens]
Length = 655
Score = 84.3 bits (207), Expect = 3e-16
Identities = 49/167 (29%), Positives = 95/167 (56%), Gaps = 6/167 (3%)
Query: 321 LFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQEL 380
+F +PL +E+ G+R+P +F++ I +E+ G++ EG+ R+ G IK+ EL
Sbjct: 189 IFGIPLADAVERTMM-YDGIRLPAVFRECIDYVEKYGMKCEGIYRVSG----IKSKVDEL 243
Query: 381 EAKF-YEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQAL 439
+A + E + N E + + ASLLK ++R+LP+ LL+ E + F+ T+ +++Q
Sbjct: 244 KAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEF 303
Query: 440 NLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
L+ LP+ N + L+ + VI + + KM + N+++V++P +
Sbjct: 304 QRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
sapiens]
Length = 731
Score = 82.0 bits (201), Expect = 2e-15
Identities = 53/169 (31%), Positives = 83/169 (49%), Gaps = 22/169 (13%)
Query: 339 GMRIPLIFQKLISRIEERGLETEGLLRIPG---AAIRIKNLCQELEAKFYEGTF------ 389
G +P + I+ +++RGL+ +G+ R+ G +++ L A +G +
Sbjct: 533 GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQP 592
Query: 390 -----------NWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438
W+ + H LKLF+RELPQPL+ L F+A L +Q L
Sbjct: 593 GQEGRLDLDSTEWDDI--HVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQ 650
Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLF 487
+ L+ +P N DTL+ LLE L RVI + +KN+MT N+ +V P LF
Sbjct: 651 IQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 699
>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
sapiens]
Length = 547
Score = 82.0 bits (201), Expect = 2e-15
Identities = 53/169 (31%), Positives = 83/169 (49%), Gaps = 22/169 (13%)
Query: 339 GMRIPLIFQKLISRIEERGLETEGLLRIPG---AAIRIKNLCQELEAKFYEGTF------ 389
G +P + I+ +++RGL+ +G+ R+ G +++ L A +G +
Sbjct: 349 GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQP 408
Query: 390 -----------NWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438
W+ + H LKLF+RELPQPL+ L F+A L +Q L
Sbjct: 409 GQEGRLDLDSTEWDDI--HVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQ 466
Query: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLF 487
+ L+ +P N DTL+ LLE L RVI + +KN+MT N+ +V P LF
Sbjct: 467 IQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 515
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 81.3 bits (199), Expect = 3e-15
Identities = 62/212 (29%), Positives = 104/212 (49%), Gaps = 9/212 (4%)
Query: 279 LAPQDMK-KVCHLALIELTALYDVLGIELKQQKAVKIKT---KDSGLFCVPLTALLEQDQ 334
L PQ ++ K H +IE+ + ++ + +T K +G+F V ++ + ++++
Sbjct: 552 LDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRER 611
Query: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394
KVP I ++ + +E+RG+E G+ RI G A I+ L +A + +
Sbjct: 612 SKVP-----YIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM 666
Query: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTL 454
+ A LKL+ RELP+PLL+ AF L + + L+ LPD N T
Sbjct: 667 DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITF 726
Query: 455 KALLEFLQRVIDNKEKNKMTVMNVAMVMAPNL 486
LLE L+RV + + NKM++ N+A V P L
Sbjct: 727 LFLLEHLKRVAEKEPINKMSLHNLATVFGPTL 758
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 81.3 bits (199), Expect = 3e-15
Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 21/243 (8%)
Query: 343 PLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEG---TFNWESVKQHDA 399
P++ ++ + I +RGL+ EGL R+PG A NL +EL+ F G +F+ + H
Sbjct: 58 PMLVEQCVDFIRQRGLKEEGLFRLPGQA----NLVKELQDAFDCGEKPSFD-SNTDVHTV 112
Query: 400 ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQ--LQALNLLVILLPDANRDTLKAL 457
ASLLKL++RELP+P++ + F + L +K+++ ++ L V LP N + LK +
Sbjct: 113 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 172
Query: 458 LEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLL-I 516
FL V NKM+V N+A V PN+ L+ + + GT L+ +
Sbjct: 173 CRFLDEVQSYSGVNKMSVQNLATVFGPNI-------LRPKVEDPLTIMEGTVVVQQLMSV 225
Query: 517 KYQKLLWTIPKFIVNQVRKQ---NTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTNDAD 573
K PK Q + Q + N + K M +L K + + + S + ++
Sbjct: 226 MISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSE 285
Query: 574 VPQ 576
PQ
Sbjct: 286 SPQ 288
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 81.3 bits (199), Expect = 3e-15
Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 21/243 (8%)
Query: 343 PLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEG---TFNWESVKQHDA 399
P++ ++ + I +RGL+ EGL R+PG A NL +EL+ F G +F+ + H
Sbjct: 60 PMLVEQCVDFIRQRGLKEEGLFRLPGQA----NLVKELQDAFDCGEKPSFD-SNTDVHTV 114
Query: 400 ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQ--LQALNLLVILLPDANRDTLKAL 457
ASLLKL++RELP+P++ + F + L +K+++ ++ L V LP N + LK +
Sbjct: 115 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 174
Query: 458 LEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLL-I 516
FL V NKM+V N+A V PN+ L+ + + GT L+ +
Sbjct: 175 CRFLDEVQSYSGVNKMSVQNLATVFGPNI-------LRPKVEDPLTIMEGTVVVQQLMSV 227
Query: 517 KYQKLLWTIPKFIVNQVRKQ---NTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTNDAD 573
K PK Q + Q + N + K M +L K + + + S + ++
Sbjct: 228 MISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSE 287
Query: 574 VPQ 576
PQ
Sbjct: 288 SPQ 290
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 81.3 bits (199), Expect = 3e-15
Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 21/243 (8%)
Query: 343 PLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEG---TFNWESVKQHDA 399
P++ ++ + I +RGL+ EGL R+PG A NL +EL+ F G +F+ + H
Sbjct: 153 PMLVEQCVDFIRQRGLKEEGLFRLPGQA----NLVKELQDAFDCGEKPSFD-SNTDVHTV 207
Query: 400 ASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQ--LQALNLLVILLPDANRDTLKAL 457
ASLLKL++RELP+P++ + F + L +K+++ ++ L V LP N + LK +
Sbjct: 208 ASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYI 267
Query: 458 LEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLL-I 516
FL V NKM+V N+A V PN+ L+ + + GT L+ +
Sbjct: 268 CRFLDEVQSYSGVNKMSVQNLATVFGPNI-------LRPKVEDPLTIMEGTVVVQQLMSV 320
Query: 517 KYQKLLWTIPKFIVNQVRKQ---NTENHKKDKRAMKKLLKKMAYDREKYEKQDKSTNDAD 573
K PK Q + Q + N + K M +L K + + + S + ++
Sbjct: 321 MISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSE 380
Query: 574 VPQ 576
PQ
Sbjct: 381 SPQ 383
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,488,518
Number of Sequences: 37866
Number of extensions: 1018187
Number of successful extensions: 3915
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 3570
Number of HSP's gapped (non-prelim): 364
length of query: 663
length of database: 18,247,518
effective HSP length: 109
effective length of query: 554
effective length of database: 14,120,124
effective search space: 7822548696
effective search space used: 7822548696
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.