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Search of human proteins with 39780597
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39780597 PNMA-like 1 isoform a [Homo sapiens]
(439 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39780597 PNMA-like 1 isoform a [Homo sapiens] 887 0.0
gi|156766054 PNMA-like 1 isoform b [Homo sapiens] 743 0.0
gi|52486265 paraneoplastic antigen MA1 [Homo sapiens] 151 1e-36
gi|19923584 modulator of apoptosis 1 [Homo sapiens] 141 1e-33
gi|11464969 paraneoplastic antigen MA2 [Homo sapiens] 137 1e-32
gi|142976816 paraneoplastic cancer-testis-brain antigen [Homo sa... 135 7e-32
gi|156766066 paraneoplastic antigen like 5 [Homo sapiens] 132 6e-31
gi|156766064 paraneoplastic antigen like 5 [Homo sapiens] 132 6e-31
gi|24308384 paraneoplastic antigen like 5 [Homo sapiens] 132 6e-31
gi|146219841 PNMA-like 2 [Homo sapiens] 117 3e-26
gi|239746972 PREDICTED: hypothetical protein XP_002343899 [Homo ... 110 2e-24
gi|239746970 PREDICTED: hypothetical protein XP_002343898 [Homo ... 110 2e-24
gi|239746974 PREDICTED: hypothetical protein XP_002343900 [Homo ... 110 3e-24
gi|187607308 paraneoplastic antigen like 6A [Homo sapiens] 110 3e-24
gi|169216514 PREDICTED: similar to paraneoplastic antigen MA2 [H... 109 6e-24
gi|169216749 PREDICTED: similar to Putative paraneoplastic antig... 109 6e-24
gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [H... 104 1e-22
gi|169216516 PREDICTED: similar to paraneoplastic antigen MA1 [H... 104 1e-22
gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [H... 104 1e-22
gi|169216507 PREDICTED: similar to hCG1645335 [Homo sapiens] 102 9e-22
gi|169216732 PREDICTED: similar to hCG1645335 [Homo sapiens] 102 9e-22
gi|199559779 coiled-coil domain containing 8 [Homo sapiens] 69 1e-11
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 64 4e-10
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 64 4e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 52 8e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 52 1e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 52 1e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 48 2e-05
gi|56676330 HP1-BP74 [Homo sapiens] 48 2e-05
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 47 3e-05
>gi|39780597 PNMA-like 1 isoform a [Homo sapiens]
Length = 439
Score = 887 bits (2291), Expect = 0.0
Identities = 439/439 (100%), Positives = 439/439 (100%)
Query: 1 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIF 60
MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIF
Sbjct: 1 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIF 60
Query: 61 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT 120
VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT
Sbjct: 61 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT 120
Query: 121 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA 180
WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA
Sbjct: 121 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA 180
Query: 181 EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR 240
EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR
Sbjct: 181 EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR 240
Query: 241 SRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEE 300
SRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEE
Sbjct: 241 SRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEE 300
Query: 301 LALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAP 360
LALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAP
Sbjct: 301 LALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAP 360
Query: 361 MRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRG 420
MRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRG
Sbjct: 361 MRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRG 420
Query: 421 PKAKPEGSPRRATNESRKV 439
PKAKPEGSPRRATNESRKV
Sbjct: 421 PKAKPEGSPRRATNESRKV 439
>gi|156766054 PNMA-like 1 isoform b [Homo sapiens]
Length = 378
Score = 743 bits (1919), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIF 60
MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIF
Sbjct: 1 MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIF 60
Query: 61 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT 120
VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT
Sbjct: 61 VREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRT 120
Query: 121 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA 180
WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA
Sbjct: 121 WEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAA 180
Query: 181 EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR 240
EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR
Sbjct: 181 EFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSR 240
Query: 241 SRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEE 300
SRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEE
Sbjct: 241 SRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEE 300
Query: 301 LALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAP 360
LALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAP
Sbjct: 301 LALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAP 360
Query: 361 MRKKKK 366
MRKKKK
Sbjct: 361 MRKKKK 366
>gi|52486265 paraneoplastic antigen MA1 [Homo sapiens]
Length = 353
Score = 151 bits (382), Expect = 1e-36
Identities = 81/155 (52%), Positives = 106/155 (68%), Gaps = 5/155 (3%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MAM LLEDWCRGM+V+ R+LLV GIP +C +AEIEETL + P YR+L ++F REE
Sbjct: 1 MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEETLQAAM-PQVSYRMLGRMFWREE 59
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDV 124
N KAAL+E+ V+ + IPRE PG+GGVW+V+ + PT DAEFL+ L+ FL EG T +DV
Sbjct: 60 NAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPTSDAEFLERLHLFLAREGWTVQDV 119
Query: 125 VRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQ 159
R+L +PT + PE AE L +L V+Q
Sbjct: 120 ARVLGFQNPTPTPG----PEMPAEMLNYILDNVIQ 150
>gi|19923584 modulator of apoptosis 1 [Homo sapiens]
Length = 351
Score = 141 bits (356), Expect = 1e-33
Identities = 75/194 (38%), Positives = 110/194 (56%), Gaps = 2/194 (1%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
M + LLEDWCRGM+++ ++LL+ GI + C AEIEE L L+PLG YR+L ++F R+E
Sbjct: 1 MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDE 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDV 124
N K AL+ + + + +P+E PG+GG+WRV+ + P D FL LNEFL EG T ++
Sbjct: 61 NRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGEL 120
Query: 125 VRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMD-AEIRSREEARAQEAAEFE 183
R L + +L Q PE WA L L A+ + C+ ++R + E E E
Sbjct: 121 SRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGE-E 179
Query: 184 EMAAWALAAGRKVK 197
E W + +K
Sbjct: 180 EFGRWMFHTTQMIK 193
>gi|11464969 paraneoplastic antigen MA2 [Homo sapiens]
Length = 364
Score = 137 bits (346), Expect = 1e-32
Identities = 83/201 (41%), Positives = 108/201 (53%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ LLEDWCR M VD +SL+VTGIP D +AEI+E L L LG YR+L KIF ++E
Sbjct: 1 MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQE 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDV 124
N A L+E+ E ++S IP E G+GGVW+V+ + P QD EFL+ LN FL+ EG+T +
Sbjct: 61 NANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGM 120
Query: 125 VRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAAEFEE 184
R L + + PE A LG + Q + M A A E E
Sbjct: 121 FRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAPEEES 180
Query: 185 MAAWALAAGRKVKKEPGLAAE 205
W A VK+ P AE
Sbjct: 181 FEVWLEQATEIVKEWPVTEAE 201
>gi|142976816 paraneoplastic cancer-testis-brain antigen [Homo
sapiens]
Length = 463
Score = 135 bits (340), Expect = 7e-32
Identities = 77/222 (34%), Positives = 117/222 (52%), Gaps = 14/222 (6%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
M + LL+DWCRG ++ R +L+ GIPEDCG+ E EETL LG YRV+ ++F REE
Sbjct: 1 MPLTLLQDWCRGEHLNTRRCMLILGIPEDCGEDEFEETLQEACRHLGRYRVIGRMFRREE 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDV 124
N +A L+E+ + ++ + +PRE PG+GG W V+ + D EFL LN FL+ E RT D+
Sbjct: 61 NAQAILLELAQDIDYALLPREIPGKGGPWEVIVKPRNSDGEFLNRLNRFLEEERRTVSDM 120
Query: 125 VRLLQLNHPTLSQNQHQPPE--NWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAAEF 182
R+L + + PE WA+ LG + +++ + + + S A F
Sbjct: 121 NRVLGSDTNCSAPRVTISPEFWTWAQTLGAAVQPLLEQMLYRELRVFSGNTISIPGALAF 180
Query: 183 --------EEMAAWALAAGRKVKK----EPGLAAEVGSALKA 212
E + W + G K ++ G A +V S L+A
Sbjct: 181 DAWLEHTTEMLQMWQVPEGEKRRRLMECLRGPALQVVSGLRA 222
>gi|156766066 paraneoplastic antigen like 5 [Homo sapiens]
Length = 448
Score = 132 bits (332), Expect = 6e-31
Identities = 61/124 (49%), Positives = 83/124 (66%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ LLEDWC+GM++D ++LL+ GIP +C + EI++T+ L PL YRVL ++F RE+
Sbjct: 1 MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDV 124
N KA IE+ + VN +T+P PG+GG W VV + D EFL LN FL EGR+ DV
Sbjct: 61 NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 120
Query: 125 VRLL 128
R L
Sbjct: 121 ARAL 124
>gi|156766064 paraneoplastic antigen like 5 [Homo sapiens]
Length = 448
Score = 132 bits (332), Expect = 6e-31
Identities = 61/124 (49%), Positives = 83/124 (66%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ LLEDWC+GM++D ++LL+ GIP +C + EI++T+ L PL YRVL ++F RE+
Sbjct: 1 MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDV 124
N KA IE+ + VN +T+P PG+GG W VV + D EFL LN FL EGR+ DV
Sbjct: 61 NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 120
Query: 125 VRLL 128
R L
Sbjct: 121 ARAL 124
>gi|24308384 paraneoplastic antigen like 5 [Homo sapiens]
Length = 448
Score = 132 bits (332), Expect = 6e-31
Identities = 61/124 (49%), Positives = 83/124 (66%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ LLEDWC+GM++D ++LL+ GIP +C + EI++T+ L PL YRVL ++F RE+
Sbjct: 1 MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQDTVKAGLQPLCAYRVLGRMFRRED 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDV 124
N KA IE+ + VN +T+P PG+GG W VV + D EFL LN FL EGR+ DV
Sbjct: 61 NAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRNPDDEFLSRLNYFLKDEGRSMTDV 120
Query: 125 VRLL 128
R L
Sbjct: 121 ARAL 124
>gi|146219841 PNMA-like 2 [Homo sapiens]
Length = 635
Score = 117 bits (292), Expect = 3e-26
Identities = 65/153 (42%), Positives = 88/153 (57%), Gaps = 1/153 (0%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MAM+LL+DWCR ++VD HR+LLVTGIPE QA++E L L PLG +R+ + + E
Sbjct: 1 MAMSLLQDWCRSLDVDAHRALLVTGIPEGLEQADVEAVLQPTLLPLGTFRLRHMKALMNE 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTW-ED 123
+AAL+E E VN + IPRE PG+ GVWRV+ +D QD L+ + L +G T +
Sbjct: 61 KAQAALVEFVEDVNHAAIPREIPGKDGVWRVLWKDRAQDTRVLRQMRRLLLDDGPTQAAE 120
Query: 124 VVRLLQLNHPTLSQNQHQPPENWAEALGVLLGA 156
+ P S+ Q Q G LLGA
Sbjct: 121 AGTPGEAPTPPASETQAQDSGEVTGQAGSLLGA 153
Score = 46.2 bits (108), Expect = 6e-05
Identities = 52/208 (25%), Positives = 78/208 (37%), Gaps = 32/208 (15%)
Query: 218 WNATEDQHEPTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKG----------INSNS 267
W+ + LV A+ + K++K + E +K PKG N
Sbjct: 438 WSEHREDEGGLLELVALLAAQDMAEVMKEEKENAWEGGKYKYPKGKLGEVLALLAARENM 497
Query: 268 TANLEDPEVGDAESMAISEPIKGSRKPCVNKEELALKKPMAKCAWKGPR------EPPQD 321
+N E D +S SE + E+ A +KP AK A PR PP
Sbjct: 498 GSNEGSEEASDEQSEEESEDTESEAS---EPEDRASRKPRAKRARTAPRGLTPAGAPPTA 554
Query: 322 ARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSED 381
+ A GG G P+KKA + SA++ A +KKK S G ++
Sbjct: 555 SGARKTRAGGRGR-----GRGVTPEKKAGSRGSAQDDAAGSRKKKGSAGAGAHARAGEAK 609
Query: 382 GRKKPVMPKKGPGSRREASDQKAPRGQQ 409
G + P + A +KA RG++
Sbjct: 610 G--------QAPTGSKAARGKKARRGRR 629
>gi|239746972 PREDICTED: hypothetical protein XP_002343899 [Homo
sapiens]
Length = 399
Score = 110 bits (276), Expect = 2e-24
Identities = 73/226 (32%), Positives = 106/226 (46%), Gaps = 24/226 (10%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ +L+DWCR M V+ R LL+ GIPEDC AE +E+L L P+G + VL K F E+
Sbjct: 1 MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQESLEAALRPMGHFTVLGKAFREED 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEF--LKNLNEFLDAEGRTWE 122
N AAL+E+ VN + +PRE PG GG W VV EF L + F + EG+ E
Sbjct: 61 NATAALVELDREVNYALVPREIPGTGGPWNVVFVPRCSGEEFLGLGRVFHFPEQEGQMVE 120
Query: 123 DVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAAEF 182
V L + + W ++G + V+ + C + S + A F
Sbjct: 121 SVAGALGVGLRRVC---------WLRSIGQAVQPWVEAVRCQSLGVFSGRDQPAPGEESF 171
Query: 183 --------EEMAAWALAAGRKVKKE-----PGLAAEVGSALKAETP 215
E + W + R+ ++ G A ++ AL AE P
Sbjct: 172 EVWLDHTTEMLHVWQGVSERERRRRLLEGLRGTALQLVHALLAENP 217
>gi|239746970 PREDICTED: hypothetical protein XP_002343898 [Homo
sapiens]
Length = 399
Score = 110 bits (276), Expect = 2e-24
Identities = 73/226 (32%), Positives = 106/226 (46%), Gaps = 24/226 (10%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ +L+DWCR M V+ R LL+ GIPEDC AE +E+L L P+G + VL K F E+
Sbjct: 1 MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQESLEAALRPMGHFTVLGKAFREED 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEF--LKNLNEFLDAEGRTWE 122
N AAL+E+ VN + +PRE PG GG W VV EF L + F + EG+ E
Sbjct: 61 NATAALVELDREVNYALVPREIPGTGGPWNVVFVPRCSGEEFLGLGRVFHFPEQEGQMVE 120
Query: 123 DVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAAEF 182
V L + + W ++G + V+ + C + S + A F
Sbjct: 121 SVAGALGVGLRRVC---------WLRSIGQAVQPWVEAVRCQSLGVFSGRDQPAPGEESF 171
Query: 183 --------EEMAAWALAAGRKVKKE-----PGLAAEVGSALKAETP 215
E + W + R+ ++ G A ++ AL AE P
Sbjct: 172 EVWLDHTTEMLHVWQGVSERERRRRLLEGLRGTALQLVHALLAENP 217
>gi|239746974 PREDICTED: hypothetical protein XP_002343900 [Homo
sapiens]
Length = 399
Score = 110 bits (275), Expect = 3e-24
Identities = 65/160 (40%), Positives = 86/160 (53%), Gaps = 9/160 (5%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ +L+DWCR M V+ R LL+ GIPEDC AE +E+L L P+G + VL K+F E+
Sbjct: 1 MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQESLEAALRPMGHFTVLGKVFREED 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEF--LKNLNEFLDAEGRTWE 122
N AAL+E+ VN + +PRE PG GG W VV EF L + F + EG+ E
Sbjct: 61 NATAALVELDREVNYALVPREIPGTGGPWNVVFVPRCSGEEFLGLGRVFHFPEQEGQMVE 120
Query: 123 DVVRLL--QLNHPTLSQNQHQPPENWAEA-----LGVLLG 155
V L L ++ Q + W EA LGV G
Sbjct: 121 SVAGALGVGLRRVCWLRSIGQAVQPWVEAVRYQSLGVFSG 160
>gi|187607308 paraneoplastic antigen like 6A [Homo sapiens]
Length = 399
Score = 110 bits (275), Expect = 3e-24
Identities = 65/160 (40%), Positives = 86/160 (53%), Gaps = 9/160 (5%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ +L+DWCR M V+ R LL+ GIPEDC AE +E+L L P+G + VL K+F E+
Sbjct: 1 MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQESLEAALRPMGHFTVLGKVFREED 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEF--LKNLNEFLDAEGRTWE 122
N AAL+E+ VN + +PRE PG GG W VV EF L + F + EG+ E
Sbjct: 61 NATAALVELDREVNYALVPREIPGTGGPWNVVFVPRCSGEEFLGLGRVFHFPEQEGQMVE 120
Query: 123 DVVRLL--QLNHPTLSQNQHQPPENWAEA-----LGVLLG 155
V L L ++ Q + W EA LGV G
Sbjct: 121 SVAGALGVGLRRVCWLRSIGQAVQPWVEAVRYQSLGVFSG 160
>gi|169216514 PREDICTED: similar to paraneoplastic antigen MA2 [Homo
sapiens]
Length = 340
Score = 109 bits (272), Expect = 6e-24
Identities = 51/102 (50%), Positives = 68/102 (66%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ +L DWCR M V+ RSLL+ IP+DC + E +E + LSPLG YRVL K+F +E
Sbjct: 1 MALAMLRDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFRKEL 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEF 106
+AAL+E EG+N S IPR+ G+GG W+V+ DAEF
Sbjct: 61 GARAALVEFAEGLNQSLIPRQIAGKGGPWKVISLPQALDAEF 102
>gi|169216749 PREDICTED: similar to Putative paraneoplastic
antigen-like protein 6B-like protein [Homo sapiens]
Length = 340
Score = 109 bits (272), Expect = 6e-24
Identities = 51/102 (50%), Positives = 68/102 (66%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ +L DWCR M V+ RSLL+ IP+DC + E +E + LSPLG YRVL K+F +E
Sbjct: 1 MALAMLRDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFRKEL 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEF 106
+AAL+E EG+N S IPR+ G+GG W+V+ DAEF
Sbjct: 61 GARAALVEFAEGLNQSLIPRQIAGKGGPWKVISLPQALDAEF 102
>gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
sapiens]
Length = 601
Score = 104 bits (260), Expect = 1e-22
Identities = 47/95 (49%), Positives = 66/95 (69%)
Query: 2 SKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFV 61
S +A+ +L+DWCR M V+ RSLL+ IP+DC + E +E + LSPLG YRVL K+F
Sbjct: 188 SSAIALAMLQDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFR 247
Query: 62 REENVKAALIEVGEGVNLSTIPREFPGRGGVWRVV 96
+E +AAL+E EG+N S IPR+ G+GG W+V+
Sbjct: 248 KELGARAALVEFAEGLNQSLIPRQIAGKGGPWKVI 282
>gi|169216516 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
sapiens]
Length = 541
Score = 104 bits (260), Expect = 1e-22
Identities = 47/95 (49%), Positives = 66/95 (69%)
Query: 2 SKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFV 61
S +A+ +L+DWCR M V+ RSLL+ IP+DC + E +E + LSPLG YRVL K+F
Sbjct: 128 SSAIALAMLQDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFR 187
Query: 62 REENVKAALIEVGEGVNLSTIPREFPGRGGVWRVV 96
+E +AAL+E EG+N S IPR+ G+GG W+V+
Sbjct: 188 KELGARAALVEFAEGLNQSLIPRQIAGKGGPWKVI 222
>gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
sapiens]
Length = 601
Score = 104 bits (260), Expect = 1e-22
Identities = 47/95 (49%), Positives = 66/95 (69%)
Query: 2 SKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFV 61
S +A+ +L+DWCR M V+ RSLL+ IP+DC + E +E + LSPLG YRVL K+F
Sbjct: 188 SSAIALAMLQDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFR 247
Query: 62 REENVKAALIEVGEGVNLSTIPREFPGRGGVWRVV 96
+E +AAL+E EG+N S IPR+ G+GG W+V+
Sbjct: 248 KELGARAALVEFAEGLNQSLIPRQIAGKGGPWKVI 282
>gi|169216507 PREDICTED: similar to hCG1645335 [Homo sapiens]
Length = 409
Score = 102 bits (253), Expect = 9e-22
Identities = 47/92 (51%), Positives = 61/92 (66%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ +L DWCR M + RSLL+ GIP+DC + E +E + LSPLG YRVL K F +E
Sbjct: 1 MALAMLRDWCRWMGANAERSLLILGIPDDCKEHEFQEAVRAALSPLGRYRVLTKHFRKEL 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVV 96
KAAL+E E +N S IP + PG GG W+V+
Sbjct: 61 GAKAALVEFAEYLNRSLIPHQIPGNGGPWKVI 92
>gi|169216732 PREDICTED: similar to hCG1645335 [Homo sapiens]
Length = 409
Score = 102 bits (253), Expect = 9e-22
Identities = 47/92 (51%), Positives = 61/92 (66%)
Query: 5 MAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREE 64
MA+ +L DWCR M + RSLL+ GIP+DC + E +E + LSPLG YRVL K F +E
Sbjct: 1 MALAMLRDWCRWMGANAERSLLILGIPDDCKEHEFQEAVRAALSPLGRYRVLTKHFRKEL 60
Query: 65 NVKAALIEVGEGVNLSTIPREFPGRGGVWRVV 96
KAAL+E E +N S IP + PG GG W+V+
Sbjct: 61 GAKAALVEFAEYLNRSLIPHQIPGNGGPWKVI 92
>gi|199559779 coiled-coil domain containing 8 [Homo sapiens]
Length = 538
Score = 68.6 bits (166), Expect = 1e-11
Identities = 32/75 (42%), Positives = 49/75 (65%)
Query: 70 LIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDVVRLLQ 129
++++GE V+ IPRE GGVWRV+ + T++AEF + L +FL+ EGRT EDV R+++
Sbjct: 1 MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIME 60
Query: 130 LNHPTLSQNQHQPPE 144
+ P Q +P E
Sbjct: 61 KSTPHPPQPPKKPKE 75
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 63.5 bits (153), Expect = 4e-10
Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 285 SEPIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDA--RAEAESPGGASESDQDGGHE 342
S+ K S + ++ ALK ++K A K + Q + +E E+ +SES++ +
Sbjct: 144 SDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQD 203
Query: 343 SPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASD- 401
P+KKA + P RKKKK S DS+ + +PV + S +S
Sbjct: 204 FTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSS 263
Query: 402 -------QKAPRGQQPAEATASTSRGPKAKPEGSPRRATNES 436
+K PRG++PAE RG K KPE P ++++S
Sbjct: 264 SDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDS 305
Score = 30.8 bits (68), Expect = 2.5
Identities = 59/294 (20%), Positives = 107/294 (36%), Gaps = 41/294 (13%)
Query: 166 AEIRSREEARAQEAAEFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPN----NWNAT 221
A + EE ++ ++E E+ + +K +G K + P+ + A
Sbjct: 180 ASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKAD 239
Query: 222 EDQHEPTKPLVRRAGAKSRSRR---------KKQKKNSRQEAVPWKKPKGIN-------S 265
D +P + R+ + S S KK + + P KP+G S
Sbjct: 240 SDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPS 299
Query: 266 NSTANLEDPEVGDAESMAISEPIKG----SRKPCVNKEELALKKPMAKCAWKGPREPPQD 321
+S+++ + EV + + +R+ +EEL + K + RE
Sbjct: 300 SSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERAD- 358
Query: 322 ARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPM---------RKKKKVSLGPV 372
R EAE G S D+ + P KK+ P+ R+ KK + P
Sbjct: 359 -RGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQ 417
Query: 373 SYVLVDSEDGRKKPVMPKK--GPGSRREASDQKAPRGQQPAEATASTSRGPKAK 424
S S + +KP +K P +++A K R ++ +E + + K K
Sbjct: 418 S----SSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKK 467
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 63.5 bits (153), Expect = 4e-10
Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 285 SEPIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDA--RAEAESPGGASESDQDGGHE 342
S+ K S + ++ ALK ++K A K + Q + +E E+ +SES++ +
Sbjct: 144 SDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQD 203
Query: 343 SPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASD- 401
P+KKA + P RKKKK S DS+ + +PV + S +S
Sbjct: 204 FTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSS 263
Query: 402 -------QKAPRGQQPAEATASTSRGPKAKPEGSPRRATNES 436
+K PRG++PAE RG K KPE P ++++S
Sbjct: 264 SDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDS 305
Score = 30.8 bits (68), Expect = 2.5
Identities = 59/294 (20%), Positives = 107/294 (36%), Gaps = 41/294 (13%)
Query: 166 AEIRSREEARAQEAAEFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPN----NWNAT 221
A + EE ++ ++E E+ + +K +G K + P+ + A
Sbjct: 180 ASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKAD 239
Query: 222 EDQHEPTKPLVRRAGAKSRSRR---------KKQKKNSRQEAVPWKKPKGIN-------S 265
D +P + R+ + S S KK + + P KP+G S
Sbjct: 240 SDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPS 299
Query: 266 NSTANLEDPEVGDAESMAISEPIKG----SRKPCVNKEELALKKPMAKCAWKGPREPPQD 321
+S+++ + EV + + +R+ +EEL + K + RE
Sbjct: 300 SSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERAD- 358
Query: 322 ARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPM---------RKKKKVSLGPV 372
R EAE G S D+ + P KK+ P+ R+ KK + P
Sbjct: 359 -RGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQ 417
Query: 373 SYVLVDSEDGRKKPVMPKK--GPGSRREASDQKAPRGQQPAEATASTSRGPKAK 424
S S + +KP +K P +++A K R ++ +E + + K K
Sbjct: 418 S----SSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKK 467
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 52.4 bits (124), Expect = 8e-07
Identities = 68/283 (24%), Positives = 107/283 (37%), Gaps = 35/283 (12%)
Query: 171 REEARAQEAAE--FEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPT 228
+EEA++ E A+ +E A A VK+E + S +K E + A + T
Sbjct: 699 KEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 758
Query: 229 ---KPLVRRAGAKSRSRRKKQK-----KNSRQEAVPWKKPKGINSNSTANLEDPEVGDAE 280
K + AK +R K K+ +E V K P+ S + + PE +
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV--KSPEKAKSPLKEDAKAPEKEIPK 816
Query: 281 SMAISEPIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGG 340
+ P+K KP +E+ +K EPP+ A E +E +D
Sbjct: 817 KEEVKSPVKEEEKP----QEVKVK------------EPPKKAEEEKAPATPKTEEKKDSK 860
Query: 341 HESPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREAS 400
E PKK+A + P +K K S V ++ED +K P K+ P
Sbjct: 861 KEEAPKKEAPKPKVEEKKEPAVEKPKES--KVEAKKEEAEDKKKVPTPEKEAPAKVEVKE 918
Query: 401 DQKAPR-----GQQPAEATASTSRGPKAKPEGSPRRATNESRK 438
D K ++P +A A P K E +P + + K
Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEK 961
Score = 38.9 bits (89), Expect = 0.009
Identities = 58/260 (22%), Positives = 104/260 (40%), Gaps = 26/260 (10%)
Query: 165 DAEIRSREEARAQEAAEFEEMAAWALAAGRKV-KKEPGLAAEVGSALKAETPNNWNA--- 220
+A+ ++EEAR+ A +F E A + K +K E A + E P
Sbjct: 765 EAKTPAKEEARSP-ADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823
Query: 221 TEDQHEPTKPLVRRAGAKSRSRRK------KQKKNSRQEAVPWK---KPKGINSNSTANL 271
+++ +P + V+ K+ + ++KK+S++E P K KPK + +
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPK-VEEKKEPAV 882
Query: 272 EDPEVGDAESMAISEPIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDARAEAESPGG 331
E P+ E A E + +K ++E K + + A P+E + A+ E +
Sbjct: 883 EKPKESKVE--AKKEEAEDKKKVPTPEKEAPAKVEVKEDA--KPKEKTEVAKKEPDDAKA 938
Query: 332 ASESDQDGGHESPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGRKKPVMPKK 391
S E+ P+KK AK P K + + D + K+P PK
Sbjct: 939 KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE-------AKAKEDDKTLSKEPSKPKA 991
Query: 392 GPGSRREASDQKAPRGQQPA 411
+ ++DQK + + A
Sbjct: 992 EKAEKSSSTDQKDSKPPEKA 1011
Score = 37.4 bits (85), Expect = 0.027
Identities = 43/172 (25%), Positives = 72/172 (41%), Gaps = 22/172 (12%)
Query: 272 EDPEVGDAESMAISEPIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDARAEAESPGG 331
E+ E E S P + + P E K P+ + A K P E + EA+SP
Sbjct: 490 EEEEAEGGEEETKSPPAEEAASP-----EKEAKSPVKEEA-KSPAEAKSPEKEEAKSPAE 543
Query: 332 ASESDQDGGHESPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGRKKPVMPK- 390
++ +SP K++A + AK+P +K+ + P V S + K P +
Sbjct: 544 VKSPEKA---KSPAKEEAKSPPEAKSP-----EKEEAKSPAE---VKSPEKAKSPAKEEA 592
Query: 391 KGPGSRREASDQKAP---RGQQPAEATASTSRGPKAKPE-GSPRRATNESRK 438
K P + K+P + PAEA + K+ E SP +A + +++
Sbjct: 593 KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE 644
Score = 35.8 bits (81), Expect = 0.079
Identities = 43/196 (21%), Positives = 77/196 (39%), Gaps = 23/196 (11%)
Query: 255 VPWKKPKG----------INSNSTANLEDPEVGDAESMAISEPIKGSR--KPCVNKEELA 302
+P+ P+G I S ++ E + E++ + E + ++ + +EE
Sbjct: 418 IPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKE 477
Query: 303 LKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPMR 362
K+ K G E + E +SP + + +SP K++A + AK+P
Sbjct: 478 AKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP---- 533
Query: 363 KKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRGPK 422
+K+ + P V S + K P K+ S EA + + PAE +
Sbjct: 534 -EKEEAKSPAE---VKSPEKAKSPA--KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSP 587
Query: 423 AKPEG-SPRRATNESR 437
AK E SP A + +
Sbjct: 588 AKEEAKSPAEAKSPEK 603
Score = 35.4 bits (80), Expect = 0.10
Identities = 53/271 (19%), Positives = 104/271 (38%), Gaps = 32/271 (11%)
Query: 167 EIRSREEARAQEAAEFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHE 226
+++S E+ + E +E E + +V +E E A + E E++ E
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEV-TEEEEKEAKEEEGKEEEGGEEEEAE 495
Query: 227 PTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISE 286
+ + A+ + +K+ K+ +E + S A + PE +A+S A +
Sbjct: 496 GGEEETKSPPAEEAASPEKEAKSPVKE----------EAKSPAEAKSPEKEEAKSPAEVK 545
Query: 287 PIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPK 346
+ ++ P KEE + PP+ E E +E +SP K
Sbjct: 546 SPEKAKSPA--KEEA--------------KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAK 589
Query: 347 KKAVAWVSAKNP----APMRKKKKVSLGPVSYVLVDSED-GRKKPVMPKKGPGSRREASD 401
++A + AK+P +P++++ K S V +++ K K P S
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP 649
Query: 402 QKAPRGQQPAEATASTSRGPKAKPEGSPRRA 432
+KA ++ + ++ P SP +A
Sbjct: 650 EKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA 680
Score = 31.6 bits (70), Expect = 1.5
Identities = 49/218 (22%), Positives = 82/218 (37%), Gaps = 36/218 (16%)
Query: 165 DAEIRSREEARAQEAAEFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQ 224
+ EI +EE ++ E + KVK+ P A E + +T ++ +++
Sbjct: 811 EKEIPKKEEVKSPVKEEEKPQEV-------KVKEPPKKAEEEKAPATPKTEEKKDSKKEE 863
Query: 225 ---HEPTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKK----PKGINSNSTANLEDPEVG 277
E KP V + + K+ K +++E KK P+ ED +
Sbjct: 864 APKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPK 923
Query: 278 DAESMAISEP----IKGSRKPCVNKEELALKKPMAKCAWKGPREPP-------------- 319
+ +A EP K KP KE KK + K P E P
Sbjct: 924 EKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS 983
Query: 320 -QDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAK 356
+ ++ +AE +S +DQ +S P +KA +AK
Sbjct: 984 KEPSKPKAEKAEKSSSTDQ---KDSKPPEKATEDKAAK 1018
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 51.6 bits (122), Expect = 1e-06
Identities = 49/199 (24%), Positives = 76/199 (38%), Gaps = 18/199 (9%)
Query: 212 AETPNNWNATEDQHEPTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGINSNSTANL 271
A+ P Q KPL ++ G +S ++ K Q+ P K P A
Sbjct: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP--------AQQ 453
Query: 272 EDPEVGDAESMAISEP---IKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDARAEAES 328
P A+ ++P + G KP + A P + K P + P + +
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ 513
Query: 329 PGGASESDQDGGHESPPKKK-AVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGRKKPV 387
PG A S Q G PP ++ A SA+ P+P + + S PV S+ G KP+
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV------SQTGSGKPL 567
Query: 388 MPKKGPGSRREASDQKAPR 406
P S ++ Q P+
Sbjct: 568 QPPTVSPSAKQPPSQGLPK 586
Score = 35.0 bits (79), Expect = 0.14
Identities = 50/237 (21%), Positives = 85/237 (35%), Gaps = 36/237 (15%)
Query: 207 GSALKAETPNNWNATEDQHEPTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGIN-- 264
G ++K P+ Q P KP ++ G +K+ A P +P G+
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPG---------HEKSQPGPAKPPAQPSGLTKP 341
Query: 265 -SNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEELALKKPMAKCAWKGPR---EPPQ 320
+ ++ P + ++P+ ++ P ++ +KP ++ GP+ +PP
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA---QQTGSEKPSSE--QPGPKALAQPPG 396
Query: 321 DARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPMR---------KKKKVSLGP 371
+ A+ PG A Q G P ++ AK P P + K GP
Sbjct: 397 VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP 456
Query: 372 VSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPR---GQQPAEATASTSRGPKAKP 425
+ G KP P + PG + Q P QQP A + + KP
Sbjct: 457 GK--TSAQQTGPTKP--PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 51.6 bits (122), Expect = 1e-06
Identities = 49/199 (24%), Positives = 76/199 (38%), Gaps = 18/199 (9%)
Query: 212 AETPNNWNATEDQHEPTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGINSNSTANL 271
A+ P Q KPL ++ G +S ++ K Q+ P K P A
Sbjct: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP--------AQQ 453
Query: 272 EDPEVGDAESMAISEP---IKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDARAEAES 328
P A+ ++P + G KP + A P + K P + P + +
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ 513
Query: 329 PGGASESDQDGGHESPPKKK-AVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGRKKPV 387
PG A S Q G PP ++ A SA+ P+P + + S PV S+ G KP+
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV------SQTGSGKPL 567
Query: 388 MPKKGPGSRREASDQKAPR 406
P S ++ Q P+
Sbjct: 568 QPPTVSPSAKQPPSQGLPK 586
Score = 35.0 bits (79), Expect = 0.14
Identities = 50/237 (21%), Positives = 85/237 (35%), Gaps = 36/237 (15%)
Query: 207 GSALKAETPNNWNATEDQHEPTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGIN-- 264
G ++K P+ Q P KP ++ G +K+ A P +P G+
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPG---------HEKSQPGPAKPPAQPSGLTKP 341
Query: 265 -SNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEELALKKPMAKCAWKGPR---EPPQ 320
+ ++ P + ++P+ ++ P ++ +KP ++ GP+ +PP
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA---QQTGSEKPSSE--QPGPKALAQPPG 396
Query: 321 DARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPMR---------KKKKVSLGP 371
+ A+ PG A Q G P ++ AK P P + K GP
Sbjct: 397 VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP 456
Query: 372 VSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPR---GQQPAEATASTSRGPKAKP 425
+ G KP P + PG + Q P QQP A + + KP
Sbjct: 457 GK--TSAQQTGPTKP--PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 48.1 bits (113), Expect = 2e-05
Identities = 80/353 (22%), Positives = 131/353 (37%), Gaps = 68/353 (19%)
Query: 102 QDAEFLKNLNEFLDAEGRTWEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQII 161
+D + + N+F A G T +D L+ + + PE +A G + +
Sbjct: 23 RDNQLSEVANKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKA 82
Query: 162 FCMDAEIRSREEARAQEAAEFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNAT 221
D+E S EE Q A A ++V PG AA A +E+ ++ ++
Sbjct: 83 SSSDSEDSSEEEEEVQGPP-----AKKAAVPAKRVGLPPGKAA----AKASESSSSEESS 133
Query: 222 EDQHEPTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAES 281
+D E + K + +K K ++ P KK K +S+S ++ ED
Sbjct: 134 DDDDEEDQ--------KKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED-------- 177
Query: 282 MAISEPIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDAR---------AEAESPGGA 332
EP K ++KP + + + + PP+ AR A + S +
Sbjct: 178 ----EPPK-NQKPKITPVTVKAQT----------KAPPKPARAAPKIANGKAASSSSSSS 222
Query: 333 SESDQDGGHE---------SPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGR 383
S S D E + PKK+ VA K +K S S D E+ +
Sbjct: 223 SSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSS----DEEEEQ 278
Query: 384 KKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRGPKAKPEGSPRRATNES 436
KKP+ K GP S P P + + T KA + P ++ +S
Sbjct: 279 KKPMKNKPGPYS------SVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDS 325
Score = 40.0 bits (92), Expect = 0.004
Identities = 51/232 (21%), Positives = 85/232 (36%), Gaps = 25/232 (10%)
Query: 220 ATEDQHEPTKPLVRRAGAKSRS----RRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPE 275
AT + P K +V +A K+ + + + +S E KKP +++ P
Sbjct: 237 ATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPS 296
Query: 276 VGDAESMAISEPIKGS---RKPCVNKEELA---------LKKPMAKCAWKGPREPPQDAR 323
+ ++P K + ++P + E+ + KKP K P A+
Sbjct: 297 APPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAK 356
Query: 324 AEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGR 383
AES +S+SD E+P K S+ PA K V P + G+
Sbjct: 357 KAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVK--PAAAPKQPVGGGQ 414
Query: 384 KKPVMPKKGPGSRREASDQKAPRGQQ-------PAEATASTSRGPKAKPEGS 428
K S E+S + + ++ A A A+ S K P+GS
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGS 466
Score = 35.0 bits (79), Expect = 0.14
Identities = 47/221 (21%), Positives = 76/221 (34%), Gaps = 27/221 (12%)
Query: 229 KPLVRRAGAKSRSRRKKQKKNSR-QEAVPWKKPKGINSNSTANLEDPEV--GDAESMAIS 285
K L R+A + S + + ++ V KPK + + +L + G +S + S
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKA-TAKAALSLPAKQAPQGSRDSSSDS 473
Query: 286 EPIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPP 345
+ + + KKP P +P + +AES +S D E
Sbjct: 474 DSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL 533
Query: 346 KKKAVAWVSAKNPAPMRKKKK------VSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREA 399
K K +P P K G + + E+ +KK + GS ++
Sbjct: 534 KGKG-------SPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKK- 585
Query: 400 SDQKAPRGQQPAEATASTSRGPKAK---PEGSPRRATNESR 437
R Q A A T + K K P P+R E R
Sbjct: 586 ------RKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKR 620
>gi|56676330 HP1-BP74 [Homo sapiens]
Length = 553
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 14/124 (11%)
Query: 315 PREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSY 374
P++ P D+R E E +SE D + E PPK++ AK+P K+ P
Sbjct: 424 PKKEPDDSRDEDEDEDESSEEDSED-EEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPK 482
Query: 375 VLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRGPKAKPEGSPRRATN 434
V ++ G+ +P +PKK P P+ + PA+ T +S K GS ++
Sbjct: 483 VSA-AQRGKARP-LPKKAP-----------PKAKTPAKKTRPSSTVIKKPSGGSSKKPAT 529
Query: 435 ESRK 438
+RK
Sbjct: 530 SARK 533
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 47.0 bits (110), Expect = 3e-05
Identities = 45/194 (23%), Positives = 78/194 (40%), Gaps = 24/194 (12%)
Query: 239 SRSRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNK 298
S+ K+ K S+ V + + +S + E+ ++ + + + + + K
Sbjct: 181 SKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPK 240
Query: 299 EELALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNP 358
EE K P K A+K P+ ++ + E+ SP G PP+ + +A +P
Sbjct: 241 EE---KAPPPKAAFKEPKMALKETKLESTSPKGGPPPPP----PPPPRASSKRPATADSP 293
Query: 359 APMRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTS 418
P KK+K S S + PG+ S + ++PA+ +ST
Sbjct: 294 KPSAKKQKKSSSKGS----------------RSAPGTSPRTSSSSSFSDKKPAKDKSST- 336
Query: 419 RGPKAKPEGSPRRA 432
RG K K E PR A
Sbjct: 337 RGEKVKAESEPREA 350
Score = 35.4 bits (80), Expect = 0.10
Identities = 43/189 (22%), Positives = 77/189 (40%), Gaps = 22/189 (11%)
Query: 260 PKGINSNSTANLEDPEVGDAESMAISEPIK-----GSRKPCVNKEELALKKPMAKCAWKG 314
P+G ++ S + + P + A S+P K GS+ NKE KP K
Sbjct: 145 PEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKD--ANKESSKTSKPH-----KV 197
Query: 315 PREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAW------VSAKNPAPMRKKKKVS 368
+E + R ++ES + E +++ S + + A P K+ K++
Sbjct: 198 TKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMA 257
Query: 369 LGPVSYVLVDSEDGRKKPVMPKKGPGSRREAS-DQKAPRGQQPAEATASTSRGPKAKPEG 427
L + G P P S+R A+ D P ++ + S+S+G ++ P
Sbjct: 258 LKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKK---SSSKGSRSAPGT 314
Query: 428 SPRRATNES 436
SPR +++ S
Sbjct: 315 SPRTSSSSS 323
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,250,317
Number of Sequences: 37866
Number of extensions: 984806
Number of successful extensions: 5016
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 355
Number of HSP's that attempted gapping in prelim test: 4478
Number of HSP's gapped (non-prelim): 824
length of query: 439
length of database: 18,247,518
effective HSP length: 105
effective length of query: 334
effective length of database: 14,271,588
effective search space: 4766710392
effective search space used: 4766710392
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.