Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 38679909

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38679909 testis expressed sequence 2 [Homo sapiens]
         (1134 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38679909 testis expressed sequence 2 [Homo sapiens]               2262   0.0  
gi|55953110 retinoblastoma protein-binding zinc finger protein i...    52   4e-06
gi|20336260 retinoblastoma protein-binding zinc finger protein i...    52   4e-06
gi|20336258 retinoblastoma protein-binding zinc finger protein i...    52   4e-06
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    51   7e-06
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       50   1e-05
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                50   2e-05
gi|91982772 mucin 17 [Homo sapiens]                                    50   2e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        50   2e-05
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa...    47   8e-05
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap...    47   8e-05
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap...    47   8e-05
gi|42518068 trans-golgi network protein 2 [Homo sapiens]               47   1e-04
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]               47   1e-04
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]               47   1e-04
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]                47   1e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             47   1e-04
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa...    47   1e-04
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         46   2e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         46   2e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        46   2e-04
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]            46   2e-04
gi|167736355 mucin 4 isoform a [Homo sapiens]                          46   2e-04
gi|161019170 mucin 5AC [Homo sapiens]                                  45   3e-04
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       45   3e-04
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    45   4e-04
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             45   4e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    45   4e-04
gi|120953251 neuron navigator 3 [Homo sapiens]                         45   4e-04
gi|110349786 Alstrom syndrome 1 [Homo sapiens]                         45   5e-04

>gi|38679909 testis expressed sequence 2 [Homo sapiens]
          Length = 1134

 Score = 2262 bits (5861), Expect = 0.0
 Identities = 1134/1134 (100%), Positives = 1134/1134 (100%)

Query: 1    MTSLYGRHAEKTTDMPKPSAPKVHVQRSVSRDTIAIHFSASGEEEEEEEEEFREYFEEGL 60
            MTSLYGRHAEKTTDMPKPSAPKVHVQRSVSRDTIAIHFSASGEEEEEEEEEFREYFEEGL
Sbjct: 1    MTSLYGRHAEKTTDMPKPSAPKVHVQRSVSRDTIAIHFSASGEEEEEEEEEFREYFEEGL 60

Query: 61   DDQSIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESP 120
            DDQSIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESP
Sbjct: 61   DDQSIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESP 120

Query: 121  VPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTS 180
            VPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTS
Sbjct: 121  VPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTS 180

Query: 181  TLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDS 240
            TLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDS
Sbjct: 181  TLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDS 240

Query: 241  KLNLHLFKQFTQPRNTGGDSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYE 300
            KLNLHLFKQFTQPRNTGGDSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYE
Sbjct: 241  KLNLHLFKQFTQPRNTGGDSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYE 300

Query: 301  PFQLLSKIIGEESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGS 360
            PFQLLSKIIGEESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGS
Sbjct: 301  PFQLLSKIIGEESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGS 360

Query: 361  DSNIPRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVLEKCSLSALVSKEDEEFCE 420
            DSNIPRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVLEKCSLSALVSKEDEEFCE
Sbjct: 361  DSNIPRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVLEKCSLSALVSKEDEEFCE 420

Query: 421  LYTEDFDLETEGESKVDKLSDIPLKPEVLAEDGVVLDSEDEVDSAVQHPELPVKTLGFFI 480
            LYTEDFDLETEGESKVDKLSDIPLKPEVLAEDGVVLDSEDEVDSAVQHPELPVKTLGFFI
Sbjct: 421  LYTEDFDLETEGESKVDKLSDIPLKPEVLAEDGVVLDSEDEVDSAVQHPELPVKTLGFFI 480

Query: 481  MCVYVYLILPLPHYVSGLFLGIGLGFMTAVCVIWFFTPPSAHKYHKLHKNLRHWNTRSLD 540
            MCVYVYLILPLPHYVSGLFLGIGLGFMTAVCVIWFFTPPSAHKYHKLHKNLRHWNTRSLD
Sbjct: 481  MCVYVYLILPLPHYVSGLFLGIGLGFMTAVCVIWFFTPPSAHKYHKLHKNLRHWNTRSLD 540

Query: 541  IKEPEILKGWMNEIYNYDPETYHATLTHSVFVRLEGGTLRLSKPNKNISRRASYNEPKPE 600
            IKEPEILKGWMNEIYNYDPETYHATLTHSVFVRLEGGTLRLSKPNKNISRRASYNEPKPE
Sbjct: 541  IKEPEILKGWMNEIYNYDPETYHATLTHSVFVRLEGGTLRLSKPNKNISRRASYNEPKPE 600

Query: 601  VTYISQKIYDLSDSKIYLVPKTLARKRIWNKKYPICIELGQQDDFMSKAQTDKETSEEKP 660
            VTYISQKIYDLSDSKIYLVPKTLARKRIWNKKYPICIELGQQDDFMSKAQTDKETSEEKP
Sbjct: 601  VTYISQKIYDLSDSKIYLVPKTLARKRIWNKKYPICIELGQQDDFMSKAQTDKETSEEKP 660

Query: 661  PAEGSEDPKKPPRPQEGTRSSQRDQILYLFGRTGREKEEWFRRFILASKLKSEIKKSSGV 720
            PAEGSEDPKKPPRPQEGTRSSQRDQILYLFGRTGREKEEWFRRFILASKLKSEIKKSSGV
Sbjct: 661  PAEGSEDPKKPPRPQEGTRSSQRDQILYLFGRTGREKEEWFRRFILASKLKSEIKKSSGV 720

Query: 721  SGGKPAPVFLAPGLLPAHSRHNSPSGHLTHSRSSSKGSVEEIMSQPKQKELAGSVRQKML 780
            SGGKPAPVFLAPGLLPAHSRHNSPSGHLTHSRSSSKGSVEEIMSQPKQKELAGSVRQKML
Sbjct: 721  SGGKPAPVFLAPGLLPAHSRHNSPSGHLTHSRSSSKGSVEEIMSQPKQKELAGSVRQKML 780

Query: 781  LDYSVYMGRCVPQESRSPQRSPLQSAESSPTAGKKLPEVPPSEEEEQEAWVNALLGRIFW 840
            LDYSVYMGRCVPQESRSPQRSPLQSAESSPTAGKKLPEVPPSEEEEQEAWVNALLGRIFW
Sbjct: 781  LDYSVYMGRCVPQESRSPQRSPLQSAESSPTAGKKLPEVPPSEEEEQEAWVNALLGRIFW 840

Query: 841  DFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGVAVPKILQAFKPYVDHQGLW 900
            DFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGVAVPKILQAFKPYVDHQGLW
Sbjct: 841  DFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGVAVPKILQAFKPYVDHQGLW 900

Query: 901  IDLEMSYNGSFLMTLETKMNLTKLGKEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSA 960
            IDLEMSYNGSFLMTLETKMNLTKLGKEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSA
Sbjct: 901  IDLEMSYNGSFLMTLETKMNLTKLGKEPLVEALKVGEIGKEGCRPRAFCLADSDEESSSA 960

Query: 961  GSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETEFIKKKI 1020
            GSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETEFIKKKI
Sbjct: 961  GSSEEDDAPEPSGGDKQLLPGAEGYVGGHRTSKIMRFVDKITKSKYFQKATETEFIKKKI 1020

Query: 1021 EEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVH 1080
            EEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVH
Sbjct: 1021 EEVSNTPLLLTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVH 1080

Query: 1081 VTDWIEKKLEQEFQKVFVMPNMDDVYITIMHSAMDPRSTSCLLKDPPVEAADQP 1134
            VTDWIEKKLEQEFQKVFVMPNMDDVYITIMHSAMDPRSTSCLLKDPPVEAADQP
Sbjct: 1081 VTDWIEKKLEQEFQKVFVMPNMDDVYITIMHSAMDPRSTSCLLKDPPVEAADQP 1134


>gi|55953110 retinoblastoma protein-binding zinc finger protein
           isoform c [Homo sapiens]
          Length = 1481

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 47/166 (28%), Positives = 75/166 (45%), Gaps = 12/166 (7%)

Query: 85  PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
           P+  A+       LS + A + LP+   TV    SP+P  + L +   A SPG     P 
Sbjct: 797 PSSSASPHPCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEPLMS---AASPGP----PT 849

Query: 145 ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVE---- 200
            SS S SS S    SSSS  SSPS  P+ + S+  S+  + +  + ++     E+E    
Sbjct: 850 LSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGL 909

Query: 201 -PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLH 245
            P+E P  A  + ++     + +   +  ES  +S K     L++H
Sbjct: 910 KPREEPQSAAEQDVVVQETFNKNFVCNVCESPFLSIKDLTKHLSIH 955



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 52/173 (30%), Positives = 72/173 (41%), Gaps = 28/173 (16%)

Query: 58  EGLDDQSIVTGLEAKEDLYLEPQVGHD-----------PAGPAA-SPVLADGLSVSQAPA 105
           +G    S    LEA+ D  L P  G             P+ PA  +P L+ G      P 
Sbjct: 707 DGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSG---QLPPL 763

Query: 106 ILPVSKNTVK----LLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSS 161
           ++P   ++      +L    P   +L TVPL  +P SS+S     SP  ++ ++      
Sbjct: 764 LIPTDPSSPPPCPPVLTVATPPPPLLPTVPLP-APSSSASPHPCPSPLSNATAQSPLPIL 822

Query: 162 SPLSSPSKSPI-----LSSSASTS--TLSSAKPFMSLVKSLSTEVEPKESPHP 207
           SP  SPS SPI     L S+AS    TLSS+    S   S S+      SP P
Sbjct: 823 SPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSS-SSSSSPSP 874


>gi|20336260 retinoblastoma protein-binding zinc finger protein
            isoform b [Homo sapiens]
          Length = 1682

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 47/166 (28%), Positives = 75/166 (45%), Gaps = 12/166 (7%)

Query: 85   PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
            P+  A+       LS + A + LP+   TV    SP+P  + L +   A SPG     P 
Sbjct: 998  PSSSASPHPCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEPLMS---AASPGP----PT 1050

Query: 145  ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVE---- 200
             SS S SS S    SSSS  SSPS  P+ + S+  S+  + +  + ++     E+E    
Sbjct: 1051 LSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGL 1110

Query: 201  -PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLH 245
             P+E P  A  + ++     + +   +  ES  +S K     L++H
Sbjct: 1111 KPREEPQSAAEQDVVVQETFNKNFVCNVCESPFLSIKDLTKHLSIH 1156



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 52/173 (30%), Positives = 72/173 (41%), Gaps = 28/173 (16%)

Query: 58   EGLDDQSIVTGLEAKEDLYLEPQVGHD-----------PAGPAA-SPVLADGLSVSQAPA 105
            +G    S    LEA+ D  L P  G             P+ PA  +P L+ G      P 
Sbjct: 908  DGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSG---QLPPL 964

Query: 106  ILPVSKNTVK----LLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSS 161
            ++P   ++      +L    P   +L TVPL  +P SS+S     SP  ++ ++      
Sbjct: 965  LIPTDPSSPPPCPPVLTVATPPPPLLPTVPLP-APSSSASPHPCPSPLSNATAQSPLPIL 1023

Query: 162  SPLSSPSKSPI-----LSSSASTS--TLSSAKPFMSLVKSLSTEVEPKESPHP 207
            SP  SPS SPI     L S+AS    TLSS+    S   S S+      SP P
Sbjct: 1024 SPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSS-SSSSSPSP 1075


>gi|20336258 retinoblastoma protein-binding zinc finger protein
            isoform a [Homo sapiens]
          Length = 1718

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 47/166 (28%), Positives = 75/166 (45%), Gaps = 12/166 (7%)

Query: 85   PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
            P+  A+       LS + A + LP+   TV    SP+P  + L +   A SPG     P 
Sbjct: 998  PSSSASPHPCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEPLMS---AASPGP----PT 1050

Query: 145  ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVE---- 200
             SS S SS S    SSSS  SSPS  P+ + S+  S+  + +  + ++     E+E    
Sbjct: 1051 LSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGL 1110

Query: 201  -PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLH 245
             P+E P  A  + ++     + +   +  ES  +S K     L++H
Sbjct: 1111 KPREEPQSAAEQDVVVQETFNKNFVCNVCESPFLSIKDLTKHLSIH 1156



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 52/173 (30%), Positives = 72/173 (41%), Gaps = 28/173 (16%)

Query: 58   EGLDDQSIVTGLEAKEDLYLEPQVGHD-----------PAGPAA-SPVLADGLSVSQAPA 105
            +G    S    LEA+ D  L P  G             P+ PA  +P L+ G      P 
Sbjct: 908  DGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSG---QLPPL 964

Query: 106  ILPVSKNTVK----LLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSS 161
            ++P   ++      +L    P   +L TVPL  +P SS+S     SP  ++ ++      
Sbjct: 965  LIPTDPSSPPPCPPVLTVATPPPPLLPTVPLP-APSSSASPHPCPSPLSNATAQSPLPIL 1023

Query: 162  SPLSSPSKSPI-----LSSSASTS--TLSSAKPFMSLVKSLSTEVEPKESPHP 207
            SP  SPS SPI     L S+AS    TLSS+    S   S S+      SP P
Sbjct: 1024 SPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSS-SSSSSPSP 1075



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 49/213 (23%), Positives = 87/213 (40%), Gaps = 25/213 (11%)

Query: 87   GPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLAS 146
            G  +SP  +D  S S        ++  ++ +++P+   +  S+ P  V   SSS     +
Sbjct: 1497 GGHSSPASSDKNSNSNHRRRTADAEIKMQSMQTPLGKTRARSSGPTQVPLPSSSFRSKQN 1556

Query: 147  SPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPH 206
                +S+  +K SSSS  +S   SPI    A  + +   KP  ++ K+ S ++  K S  
Sbjct: 1557 VKFAASVKSKKPSSSSLRNS---SPI--RMAKITHVEGKKP-KAVAKNHSAQLSSKTSRS 1610

Query: 207  PARHRHLMKTLVKSLSTDTSRQESDTVSYK-------PPDSKLNLHLFKQFTQPRNTGGD 259
                    K +++S ST  S++ +D  + K       P    L L      ++ +   G 
Sbjct: 1611 LHVRVQKSKAVLQSKSTLASKKRTDRFNIKSRERSGGPVTRSLQLAAAADLSENKREDGS 1670

Query: 260  SK------------TAPSSPLTSPSDTRSFFKV 280
            +K             +  SP  +P  TR + KV
Sbjct: 1671 AKQELKDFSYSLRLASRCSPPAAPYITRQYRKV 1703


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 91/355 (25%), Positives = 143/355 (40%), Gaps = 47/355 (13%)

Query: 133 AVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLV 192
           ++   SSSS   +SS S SS S   +SSSS  SS S S   SSS+S+S+ S +KP   L+
Sbjct: 145 SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---SSSSSSSSTSFSKPH-KLM 200

Query: 193 KSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQ 252
           K      E KE P      H  K+  K  S D ++   ++ S KP ++K    L ++   
Sbjct: 201 K------EHKEKPSKDSREH--KSAFKEPSRDHNKSSKES-SKKPKENK---PLKEEKIV 248

Query: 253 PRNTGGDSKTAPSSP--------LTSPSDTRSFFKVPEM----EAKIEDTKRRLSEVIYE 300
           P+    + K     P        +TS  D ++  K P +    E   +  K+  SE +++
Sbjct: 249 PKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFK 308

Query: 301 PFQLLSKIIGEESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGS 360
            F     +I   S   +         + S++      +ES  +   K      +     +
Sbjct: 309 SFSSAPPLILTCSADKK------QIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPN 362

Query: 361 DSNIPRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVLEKCSLSALVS---KEDEE 417
           DS++  +   KS  E        SS  SS       T S   ++  L +++     +D E
Sbjct: 363 DSDVEENISSKSDSEQPSPASSSSSSSSSF------TPSQTRQQGPLRSIMKDLHSDDNE 416

Query: 418 FCELYTEDFDLETEGESKVDKLSDIPLKPEVLAEDGVVLDSEDEVDSAVQHPELP 472
                 ED D ++E E  V++         V   DG   DSE    S+  H E P
Sbjct: 417 EESDEVEDNDNDSEMERPVNRGGS--RSRRVSLSDG--SDSESSSASSPLHHEPP 467


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 84/345 (24%), Positives = 127/345 (36%), Gaps = 68/345 (19%)

Query: 25   VQRSVSRDTIAIHFSASGEEEEEEEEEFREYFEEGLDDQSIVTGLEAKEDLYLEPQVGHD 84
            ++ SVS++   I F  + EEEE        YF        +       +DLYL P    D
Sbjct: 1109 LKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQD 1168

Query: 85   PAGPAASPVLADGLSVSQAPAILPV--------------------SKNTVKLLESPVPAA 124
            P      P    GL   +   IL +                     +  ++  E+ VPA 
Sbjct: 1169 PVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEADVPAY 1228

Query: 125  QVLSTV----------PLAVSPGSSSSGPLASSPSVSSLSEQ---KTSSSSPLSSPSKSP 171
              ++TV          PL  +  + S+ P  S P    L E    K  SS   ++PS + 
Sbjct: 1229 PKVATVPQSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSPAT 1288

Query: 172  ILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLV-KSLSTDTSRQES 230
              +++A+ ST +S     S   S S    P E        H+++TL  K  S D S +E 
Sbjct: 1289 AATTAAAASTAAS-----STASSASKTASPLE--------HILQTLFGKKKSFDPSARE- 1334

Query: 231  DTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTSP--SDTRSFFKVPEMEAKIE 288
                  PP S   L       +P+ T  D   AP  PL  P       F K   +E + E
Sbjct: 1335 ------PPGSTAGLP-----QEPKTTAEDGVPAP--PLLDPIVQQFGQFSKDKALEEE-E 1380

Query: 289  DTKRRLSEVIYEPFQLLSKIIGEESGSHR----PKALSSSASELS 329
            D +    E  Y+P +     + E    H     P+A ++   E++
Sbjct: 1381 DDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVA 1425



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 83/399 (20%), Positives = 140/399 (35%), Gaps = 57/399 (14%)

Query: 88  PAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASS 147
           PA   ++    S +   A  P  K      +  +P    LS  P   S G+S++     +
Sbjct: 561 PAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATP---SSGASAARQAGPA 617

Query: 148 PSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHP 207
           P+ ++ + +K   S+ L    + P++ S    S        MS   S     +P      
Sbjct: 618 PAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPS-----QPNSQIRQ 672

Query: 208 ARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLH----LFKQFTQPRNTGGDSKTA 263
              R L + L K ++        D +  +    K+ LH    +F  F    N       +
Sbjct: 673 NIRRSLKEILWKRVN-----DSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRS 727

Query: 264 PSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRP-KALS 322
               L  P +   F +V   E  +    R       +P +L+SK +   +   RP +++ 
Sbjct: 728 IMFNLKDPKNQGLFHRVLREEISLAKLVR------LKPEELVSKEL--STWKERPARSVM 779

Query: 323 SSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSNIPRSDH---PKSTGEPTRE 379
            S ++L        H ES      +E   D E     SDS   +      P+ +  P  +
Sbjct: 780 ESRTKL--------HNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLD 831

Query: 380 I------ELKSSQGSSLKDLGLKTSSLVL---------EKCSLSALVSKEDEEFCELYTE 424
           +      +  S   + L DL  K  +  +         +K  LSA V KED +       
Sbjct: 832 VFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLK----SKH 887

Query: 425 DFDLETEGESKVDKLSDIPLKPEVLAEDGVVLDSEDEVD 463
           D           D++    + PEV +E G+   S   VD
Sbjct: 888 DSSAPDPAPDSADEVMPEAV-PEVASEPGLESASHPNVD 925


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 50/183 (27%), Positives = 77/183 (42%), Gaps = 19/183 (10%)

Query: 35  AIHFSASGEEEEE------------EEEEFREYFEEGLDDQSIVTGLEAKEDLYLEPQVG 82
           ++HF  S  E E+            + E+F+   +  +   S  T L   +     PQ  
Sbjct: 707 SLHFPQSPPEWEDSLSPLHFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSFPESPQ-- 764

Query: 83  HDPAGPAASPV---LADGLSVSQAPAILPVSKNTVKLLESPV--PAAQVLSTVPLAVSPG 137
             P GPA SP+   ++   S + A  +    ++     E P   P    +S+ P + S  
Sbjct: 765 SPPEGPAQSPLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSS 824

Query: 138 SSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLST 197
            S S P++S PS +S S  K+S  SPL SP  S   S+S S  +  S+ P      S  T
Sbjct: 825 LSQSSPVSSFPSSTSSSLSKSSPESPLQSPVISFSSSTSLSPFSEESSSPVDEYTSSSDT 884

Query: 198 EVE 200
            +E
Sbjct: 885 LLE 887



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 46/172 (26%), Positives = 68/172 (39%), Gaps = 26/172 (15%)

Query: 88  PAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVS----PGSSSSGP 143
           P + P   D LS    P   P  ++    L+SPV      +++ L  S    P S   GP
Sbjct: 711 PQSPPEWEDSLSPLHFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSFPESPQSPPEGP 770

Query: 144 LAS----------SPSVSSLSEQKTSS-----SSPLSSPSKSPILSSSAST-STLSSAKP 187
             S          S +++SL +    S       P  SP +SP+ S  +ST S+LS + P
Sbjct: 771 AQSPLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSP 830

Query: 188 FMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPD 239
             S   S S+ +       P      +++ V S S+ TS       S  P D
Sbjct: 831 VSSFPSSTSSSLSKSSPESP------LQSPVISFSSSTSLSPFSEESSSPVD 876



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 66/264 (25%), Positives = 98/264 (37%), Gaps = 38/264 (14%)

Query: 88  PAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASS 147
           P + P   D  S  Q P   P S +T+  L+S           P + S G  SS PL   
Sbjct: 22  PQSCPEGEDSQSPLQIPQSSPESDDTLYPLQS-----------PQSRSEGEDSSDPLQRP 70

Query: 148 P-SVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESP- 205
           P    S S  +   SSP    ++SP+ +S +S     S  P    +     E E  +SP 
Sbjct: 71  PEGKDSQSPLQIPQSSPEGDDTQSPLQNSQSSPEGKDSLSPLE--ISQSPPEGEDVQSPL 128

Query: 206 -HPARHRHLMKTLVKSLSTDTSRQE-----SDTVSYKPPDSKLNLHLFKQF-TQPRNTGG 258
            +PA        L    S+  S Q        +V   P  +  +  L   F + P +T  
Sbjct: 129 QNPASSFFSSALLSIFQSSPESTQSPFEGFPQSVLQIPVSAASSSTLVSIFQSSPESTQS 188

Query: 259 DSKTAPSSPLTSPSDTRSFFK--VPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSH 316
             +  P SPL  P  +RSF    +   ++  E T+         P Q+            
Sbjct: 189 PFEGFPQSPLQIPV-SRSFSSTLLSIFQSSPERTQSTFEGFAQSPLQI------------ 235

Query: 317 RPKALSSSASELSNLSSLNGHLES 340
            P + SSS++ LS   S +   +S
Sbjct: 236 -PVSPSSSSTLLSLFQSFSERTQS 258



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 59/241 (24%), Positives = 89/241 (36%), Gaps = 23/241 (9%)

Query: 102 QAPAILPVSKNTVKLLESPVPAAQV----LSTVPLAVSPGSSSSGPLASSPSVSSLSEQK 157
           Q P     S   + +L+S   +AQ         PL +   SS S  L S    S      
Sbjct: 409 QIPMTSSFSSTLLSILQSSPESAQSAFEGFPQSPLQIPVSSSFSYTLLSLFQSSPERTHS 468

Query: 158 TSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSL-----STEVEPKESPHPARHRH 212
           T    P  SP + P+ SSS+S++ LS  +      +S       + ++  +SP    + H
Sbjct: 469 TFEGFP-QSPLQIPVSSSSSSSTLLSLFQSSPECTQSTFEGFPQSPLQIPQSPPEGENTH 527

Query: 213 LMKTLVKSLSTDTSRQESDTVSYKPP--DSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTS 270
               +V SL               PP  +  L+ H F Q              P SP   
Sbjct: 528 SPLQIVPSLPEWEDSLSPHYFPQSPPQGEDSLSPHYFPQSPPQGEDSLSPHYFPQSPQGE 587

Query: 271 PSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEE--SGSHRPKALSSSASEL 328
            S +  +F  P+   + ED+   L    Y P    S + GEE  S    P ++ SS++  
Sbjct: 588 DSLSPHYF--PQSPPQGEDSMSPL----YFP---QSPLQGEEFQSSLQSPVSICSSSTPS 638

Query: 329 S 329
           S
Sbjct: 639 S 639



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 15/119 (12%)

Query: 79  PQVGHDPAGP---AASPVLADGLSVSQAPAILPVSKNTVKLL---ESPVPAAQVLSTVPL 132
           P  G D   P     SP   D LS    P   P  ++++  L   +SP+   +  S++  
Sbjct: 568 PPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLYFPQSPLQGEEFQSSLQS 627

Query: 133 AVSPGSSSSGPLASSPSVSSLSEQ-KTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMS 190
            VS        + SS + SSL +    SS SP   P +SP+ S  +    + S  P  S
Sbjct: 628 PVS--------ICSSSTPSSLPQSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQS 678


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 59/231 (25%), Positives = 97/231 (41%), Gaps = 39/231 (16%)

Query: 89   AASPVLADGLSV--------SQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSS 140
            ++SP +A+G S+        S   +I+P+S   V   E     A  LST P+  S   ++
Sbjct: 3437 SSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSE-----ASTLSTTPVDTSTPVTT 3491

Query: 141  SGPLASSPSVSSLSEQKTSSSSPLSSP------SKSPILSSSAST--STLSSAKPFMSLV 192
            S P  SSP+ + ++   TS++   S+P      S +P+ SS AST  +T   +  F++  
Sbjct: 3492 SSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSS 3551

Query: 193  KSLST-----EVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLF 247
               S+     +V       P+     + T++ S ST  +  E+ T S    D        
Sbjct: 3552 SQASSSPATLQVTTMRMSTPSEGSSSLTTMLLS-STYVTSSEASTPSTPSVDR------- 3603

Query: 248  KQFTQPRNTGGDSKTAPSSP--LTSPSDTRSFFKVPEMEAKIEDTKRRLSE 296
               + P  T   S + P+ P  +T P  T S    P     +  T   +SE
Sbjct: 3604 ---STPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISE 3651



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 80/378 (21%), Positives = 145/378 (38%), Gaps = 43/378 (11%)

Query: 86  AGPAASPVLADGLSVSQ-APA--ILPVSKNTVKLLESPVPAAQVLSTVPLAV------SP 136
           A  ++SP  A+G S+S  AP+    P+++  + ++      A  LST P A       S 
Sbjct: 251 AQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITST 310

Query: 137 GSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLS 196
            +SSS   A   S+   +   T  S+PL+S   S +  +++  STLS      S +  ++
Sbjct: 311 EASSSPTTAEGTSIP--TSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTL--VT 366

Query: 197 TEVEPKESPHPARHRHLMKTLVKSLSTD----------TSRQESDTVSYKPPDSKLNLHL 246
           T  EP   P  A    ++ + +   ST            +  E+ T S  P DSK  +  
Sbjct: 367 TSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTT 426

Query: 247 FKQFTQPRNTGGDSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLS 306
             + +    T  D+  A S+P    +   S   +P     +  ++   S +   P    +
Sbjct: 427 ASEASSSPTTAEDTSIATSTPSEGSTPLTS---MPVSTTPVASSE--ASNLSTTPVDSKT 481

Query: 307 KIIGEESGSHRPKAL----------SSSASELSNLSSLNGHLESNNNYSIKEEECDSEGD 356
           ++      S  P             S  ++ L+++S     + S+   ++     D+   
Sbjct: 482 QVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTP 541

Query: 357 GYGSDSNIPRSDHPKSTGEPTREIELKSSQGSS-LKDLGLKTSSLVLEKCSLSALVSKED 415
              S      S  P+ T  PT       S+GS+ L ++ + T  +V  + S ++    + 
Sbjct: 542 VTTSSEASSSSTTPEGTSIPTS----TPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADS 597

Query: 416 EEFCELYTEDFDLETEGE 433
             F    +E     T  E
Sbjct: 598 NTFVTTSSEASSSSTTAE 615



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 52/202 (25%), Positives = 85/202 (42%), Gaps = 31/202 (15%)

Query: 89   AASPVLADGLSV---SQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLA 145
            ++SP  A+G S+   + +    P++   V        A   LST P+  S   ++S    
Sbjct: 844  SSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEAR 903

Query: 146  SSPSVSSLSEQKTSS----SSPLSS--PSKSPILSSSA--------------STSTLSSA 185
            SSP+ S  +   TS+    S+PL+S   S +P++SS A              +TST +++
Sbjct: 904  SSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATS 963

Query: 186  KPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLH 245
             P  +   S+ T   P E   P     +  TLV       +  E+ T+S  P DS   L 
Sbjct: 964  SPTTAEGTSIPTST-PSEGTTPLTSTPVSHTLV-------ANSEASTLSTTPVDSNTPLT 1015

Query: 246  LFKQFTQPRNTGGDSKTAPSSP 267
               + + P  T   +    S+P
Sbjct: 1016 TSTEASSPPPTAEGTSMPTSTP 1037



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 94/418 (22%), Positives = 152/418 (36%), Gaps = 58/418 (13%)

Query: 89   AASPVLADGLSVSQAP--------AILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSS 140
            ++SP  ADG S+  +           +PVS  TV   E    +  +  T     +   +S
Sbjct: 1905 SSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQAS 1964

Query: 141  SGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTE-- 198
            S P  ++   S  +   +  S+PL+S   S  L  S+  STLS+     S   + STE  
Sbjct: 1965 SSP-TTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGS 2023

Query: 199  -------------VEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLH 245
                           P E   P     +  TLV S        E +T+S  P DSK  + 
Sbjct: 2024 SSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVS-------SEGNTLSTTPVDSKTQVT 2076

Query: 246  LFKQFTQPRNTGGDSKT--APS-------------SPLTSP-SDTRSFFKVPEMEAKIED 289
               + +      G S T  APS             +P+ SP + T S   V      I  
Sbjct: 2077 NSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITS 2136

Query: 290  TKRRLSEVIYEPFQLLSKIIGEESGSHRPKALSS---SASELSNLSSLNGHLESNNNYSI 346
            T+   S +  E   + +    +         +S+   ++S +S LS+      +    S 
Sbjct: 2137 TEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNST 2196

Query: 347  KEEECDSEGDGYGSDSNIPRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVLEKCS 406
            +     +  +G    ++ P       T  P   + + +S+ S+L    + TS+ V    S
Sbjct: 2197 EARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPV--TTS 2254

Query: 407  LSALVSKEDEEFCELYTEDFDLETEGESKVDKLSDIPLKPEVLAEDGVVLDSEDEVDS 464
              A  S    E   + T      +EG +    L+ IP+   ++A   V   S   VDS
Sbjct: 2255 TEATSSPTTAEGTSIPTSTL---SEGTT---PLTSIPVSHTLVANSEVSTLSTTPVDS 2306



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 57/224 (25%), Positives = 85/224 (37%), Gaps = 37/224 (16%)

Query: 89   AASPVLADGLSVSQAPAILPVSKNTVKLLESPVPA-------AQVLSTVPLAVSPGSSSS 141
            ++SP  A+G S+  +P     S+ T  L   PV         A  LST P+      ++S
Sbjct: 1139 SSSPTTAEGTSIPTSPP----SEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATS 1194

Query: 142  GPLASSPSVSSLSEQKTSSSSPLSSPSKS------PILSSSASTSTLSSAKPFMSLVKSL 195
               +S P  + ++   TS+    S+P  S      P+ SS AST + S     +     +
Sbjct: 1195 TEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSP----VDTSTPV 1250

Query: 196  STEVEPKESPHPARHRHLMKTLVKSLST-DTSRQESDTVSYKPPDSKLNLHLFKQFTQPR 254
            +T  E   SP  A    L  +     ST  TS   S T+   P  S L        T P 
Sbjct: 1251 TTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTL-------LTTPV 1303

Query: 255  NTGG--------DSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDT 290
            +T G         S   P+   + P+ T S  + P     +  T
Sbjct: 1304 DTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTT 1347



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 71/323 (21%), Positives = 123/323 (38%), Gaps = 28/323 (8%)

Query: 89   AASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVP--LAVSPGSSSSGPLAS 146
            ++SP  A+G S+  +P     S+ T  L   PV    V+S+    L+ +P  +S+ P+ +
Sbjct: 2435 SSSPTTAEGTSIPTSPP----SEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTST-PMTT 2489

Query: 147  SPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPH 206
            S   SS          P+S+ S+   L +S   ST   A P  S   +LST   P +S  
Sbjct: 2490 STEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEAS---TLST--TPVDSNS 2544

Query: 207  PARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSS 266
            P     +  T + S +T        T +Y    + L        + P +T   + +  S+
Sbjct: 2545 PV----VTSTEISSSATSAEGTSMPTSTYSEGSTPLR-------SMPVSTKPLASSEAST 2593

Query: 267  PLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRPKALSSSAS 326
              T+P DT          +    T +  S  I  P ++ + +      S     +  ++S
Sbjct: 2594 LSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLT-----SILVSTMPVASS 2648

Query: 327  ELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSNIPRSDHPKSTGEPTREIELKSSQ 386
            E S LS+      +    S       +  +G    ++ P       T        L +S+
Sbjct: 2649 EASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSE 2708

Query: 387  GSSLKDLGLKTSSLVLEKCSLSA 409
             S+L    + TS+ V      S+
Sbjct: 2709 ASTLSTTPVDTSTPVTTSAEASS 2731



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 67/285 (23%), Positives = 106/285 (37%), Gaps = 38/285 (13%)

Query: 33  TIAIHFSASGEEEEEEEEEFREYFEEG--LDDQSIVTGLEAKEDLYLEPQVGHDPAGPAA 90
           T +   S+S    E        Y E G  +   S+ T L A  +         D   P  
Sbjct: 602 TTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVT 661

Query: 91  SPVLADGLSVSQAPAILPVSKNT---VKLLESPVPA-------AQVLSTVPLAVSPGSSS 140
           +   A   S +     +P S  T     L   PV         A  LST P+  S   ++
Sbjct: 662 TSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTT 721

Query: 141 SGPLASSPSVSSLSEQKTSS----SSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLS 196
           S   +SSP+ +  +   TS+    S+PL+S   S  L +S+  STLS+    +     ++
Sbjct: 722 STEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTP--LDTSTHIT 779

Query: 197 TEVEPKESP-----------HPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLH 245
           T  E   SP            P+    L+ ++  S++  TS  E+ T+S  P DS   + 
Sbjct: 780 TSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTS-PEASTLSTTPVDSNSPV- 837

Query: 246 LFKQFTQPRNTGGDSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDT 290
                    +T   S   P+   + P+ T S  + P     +  T
Sbjct: 838 -------TTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTT 875



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 70/323 (21%), Positives = 123/323 (38%), Gaps = 45/323 (13%)

Query: 89   AASPVLADGLSV---SQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLA 145
            ++SP  A+G  +   + +    P++   V      +P A  LST P+       S+ P+ 
Sbjct: 3025 SSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPV------DSNSPVV 3078

Query: 146  SSPSVSSLSEQKTSSSSPLS--SPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKE 203
            +S  VSS       +S P+S  S   +P+     ST+ ++S     S + +LST      
Sbjct: 3079 TSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTS-----SAISTLSTTPVDTS 3133

Query: 204  SP-HPARHRHLMKTLVK--SLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDS 260
            +P   +   H   T  +  S+ T T  + S  ++Y P  + L +      +   +T   +
Sbjct: 3134 TPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVV------SSEDSTLSAT 3187

Query: 261  KTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRPKA 320
                S+P+T+ ++  S                 ++ +   P             S+ P A
Sbjct: 3188 PVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPV------------SNTPVA 3235

Query: 321  LSSSASELSNLSSLNGHLESNNNYSIKEEECDS--EGDGYGSDSNIPRSDHPKSTGEPTR 378
             SS AS LS        ++SN   +   E   S    +G    ++ P       T  P  
Sbjct: 3236 -SSEASILSTTP-----VDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVS 3289

Query: 379  EIELKSSQGSSLKDLGLKTSSLV 401
               + SS+ S+L      TS+ V
Sbjct: 3290 TTTVASSETSTLSTTPADTSTPV 3312



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 44/188 (23%), Positives = 82/188 (43%), Gaps = 16/188 (8%)

Query: 65   IVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAA 124
            + T ++ K  +    +V   P     + +     S  + P +  +  NT  +  S   A 
Sbjct: 1299 LTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTP-LTSIPVNTTLVASS---AI 1354

Query: 125  QVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSP------SKSPILSSSAS 178
             +LST P+  S   ++S    SSP+ S  +    S+ S  ++P      S +P++SS AS
Sbjct: 1355 SILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAS 1414

Query: 179  T---STLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSL---STDTSRQESDT 232
            T   + + ++ P  +  ++ S+    +    P       KT +KS+   +T  +  E+ T
Sbjct: 1415 TLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEAST 1474

Query: 233  VSYKPPDS 240
            +S  P DS
Sbjct: 1475 LSTTPVDS 1482



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 53/232 (22%), Positives = 102/232 (43%), Gaps = 35/232 (15%)

Query: 86   AGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPV-------PAAQVLSTVPLAVSPGS 138
            A  ++SP  A+G S+  +      S+ +  L   PV       P A  L T P+      
Sbjct: 1254 AETSSSPTTAEGTSLPTSTT----SEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPV 1309

Query: 139  SSSGPLASSPSVSSLSEQKTSSSS----PLSS-PSKSPILSSSA----STSTLSSAKPFM 189
             +S  ++SSP+ +  +   TS+ S    PL+S P  + +++SSA    ST+ + ++ P  
Sbjct: 1310 VTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVT 1369

Query: 190  SLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTS---RQESDTVSYKPPDSKLNLHL 246
            +  ++ S+    + +  P  +     T + S+   T+     E+ T+S  P D+      
Sbjct: 1370 TSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDT------ 1423

Query: 247  FKQFTQPRNTGGDSKTAPSSP--LTSPSDTRSFFKVPEMEAKIEDTKRRLSE 296
                + P  T  ++ ++P++   ++ P+ T S  K P     + +T    SE
Sbjct: 1424 ----STPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSE 1471



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 75/362 (20%), Positives = 140/362 (38%), Gaps = 50/362 (13%)

Query: 82   GHDPAGPAASPVLADGLSV-SQAPAILPVSKNTVKLLESPVP--AAQVLSTVPLAVSPGS 138
            G   A   +SP  A+G+S+ +  P+       ++ +  +PV    A  LST P+      
Sbjct: 1427 GTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPV------ 1480

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPLSSPSKS-------PILSSSASTSTLSSAKPFMSL 191
             S+ P+ +S +VSS       +S  +S+PS+        P+ +++ ++S ++S     ++
Sbjct: 1481 DSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAV 1540

Query: 192  VKS-LSTEVEPKESPHPARHRHLMKTLVKSLSTDTS----------RQESDTVSYKPPDS 240
              + ++T  +   SP  A    +  +     ST  +            E++T+S  P DS
Sbjct: 1541 TSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDS 1600

Query: 241  KLNLHLFKQFTQPRNTGGDSKT---------------APSSPLTSP-SDTRSFFKVPEME 284
            K  +    + +      G S T                 ++P+ SP + T S   V    
Sbjct: 1601 KTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNS 1660

Query: 285  AKIEDTKRRLSEVIYEPFQLLSKIIGE-----ESGSHRPKALSSSASELSNLSSLNGHLE 339
              I  T+   S    E   + +    E      S + R   ++SSA  +S LS+      
Sbjct: 1661 PVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSA--ISTLSTTPVDNS 1718

Query: 340  SNNNYSIKEEECDSEGDGYGSDSNIPRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSS 399
            +    S +     +  +G    ++ P       T  P     + SS+ S+L    + TS+
Sbjct: 1719 TPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTST 1778

Query: 400  LV 401
             V
Sbjct: 1779 PV 1780



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 48/171 (28%), Positives = 75/171 (43%), Gaps = 23/171 (13%)

Query: 89   AASPVLADGLSV---SQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLA 145
            ++SP  A+G S+   +      P++  TV+       A   LST P+  S   ++S    
Sbjct: 1669 SSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEAR 1728

Query: 146  SSPSVSSLSEQKTSSSSPLSSP------SKSPILSSSASTSTLSSAKPFMSLVKSLSTEV 199
            SSP+ S  +    S+ S  ++P      S +P+LSS AST    SA P +     ++T  
Sbjct: 1729 SSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEAST---LSATP-IDTSTPVTTST 1784

Query: 200  EPKESPHPARHRHL-MKTLVKSLSTDTS---------RQESDTVSYKPPDS 240
            E   SP  A    +   TL + ++  TS           E+ T+S  P DS
Sbjct: 1785 EATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDS 1835



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 50/180 (27%), Positives = 77/180 (42%), Gaps = 37/180 (20%)

Query: 87   GPAASPVLADGLSVSQAPAILPVSKNT--VKLLESPV----PAAQVLSTVPLAVSPGSSS 140
            G ++SP  A+G S+   P   P  ++T    +L S        A  LST P+  S   ++
Sbjct: 2669 GTSSSPTTAEGSSM---PTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTT 2725

Query: 141  SGPLASSPSVSSLSEQKTSSSSPLSSP------SKSPILSSSAS--------------TS 180
            S   +SSP+ +  +  + S+ S  S+P      S  P+ SS AS              TS
Sbjct: 2726 SAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTS 2785

Query: 181  TLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDS 240
            T +S+ P  + V S+ T   P E+  P     +  T V S        E+ T+S  P D+
Sbjct: 2786 TEASSSPTTAEVTSMPTST-PSETSTPLTSMPVNHTPVAS-------SEAGTLSTTPVDT 2837



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 48/211 (22%), Positives = 94/211 (44%), Gaps = 41/211 (19%)

Query: 89   AASPVLADGLSVSQAPAI--------LPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSS 140
            ++SP  A+G+ V  + A         +PVS   V   E     A  LST P+  S   ++
Sbjct: 2848 SSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSE-----ASTLSTTPVDTSIPVTT 2902

Query: 141  SGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILS---------SSASTSTLSSAKPFMSL 191
            S   +SSP+ +  +    S+ S +S+P  S ++S         S+ ST+ + +  P  + 
Sbjct: 2903 STEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTS 2962

Query: 192  VKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDT---SRQESDTVSYKPPDSKLNLHLFK 248
             ++ S+    + +  P       +T + S+S  T   +  E+ T+S  P D+        
Sbjct: 2963 AEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADT-------- 3014

Query: 249  QFTQPRNTGGDSKTAPSS------PLTSPSD 273
              + P  T  ++ ++P++      P+++PS+
Sbjct: 3015 --STPVTTSTEASSSPTTAEGTGIPISTPSE 3043



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 89/379 (23%), Positives = 139/379 (36%), Gaps = 68/379 (17%)

Query: 85  PAGPAASPVLADGLSVSQAPAI-LPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGP 143
           P    A+ +L   LS    P   +PVS   V   E     A   ST+P+      +++  
Sbjct: 375 PTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSE-----ASTTSTIPVDSKTFVTTASE 429

Query: 144 LASSPSVSSLSEQKTSSSSPLSSP------SKSPILSSSAS--------------TSTLS 183
            +SSP+ +  +   TS+ S  S+P      S +P+ SS AS              TST +
Sbjct: 430 ASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEA 489

Query: 184 SAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSK-- 241
           S+ P  + V S+ T   P E   P        T +   +   +  E+ T+S  P D+   
Sbjct: 490 SSSPPTAEVNSMPTST-PSEGSTPL-------TSMSVSTMPVASSEASTLSTTPVDTSTP 541

Query: 242 --LNLHLFKQFTQPRNTGGDSKTAP--SSPLTS-PSDTRSFFKVPEMEAKIEDTKRRLSE 296
              +       T P  T   + T    S+PLT+ P  TR    V   EA    T    S 
Sbjct: 542 VTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTR---LVVSSEASTTSTTPADSN 598

Query: 297 VIYEPFQLLSKIIGEESGSHRPKALSS----------------SASELSNLSSLNGHLES 340
                    S       G+  P +  S                ++SE S LS+    ++S
Sbjct: 599 TFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTT--PVDS 656

Query: 341 NNNYSIKEEECDSEGDGYGSDSNIPRSDHPKS----TGEPTREIELKSSQGSSLKDLGLK 396
           N   +   E   S     G  +++P S + +     T  P     + SS+ S+L    + 
Sbjct: 657 NTPVTTSTEATSSSTTAEG--TSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVD 714

Query: 397 TSSLVLEKCSLSALVSKED 415
           TS+ V      S+  +  D
Sbjct: 715 TSTPVTTSTEASSSPTTAD 733



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 53/205 (25%), Positives = 81/205 (39%), Gaps = 37/205 (18%)

Query: 89   AASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQV-------LSTVPLAVSPGSSSS 141
            ++ P  A+G S+   P   P S+ +  L   PV    V       LST P   S   ++ 
Sbjct: 1021 SSPPPTAEGTSM---PTSTP-SEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTY 1076

Query: 142  GPLASSPSVSSLSEQKTSS----SSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLST 197
               +SS + +  +   TS+    S+PL+S   S  L  S+  STLS+     S+  + ST
Sbjct: 1077 SQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTST 1136

Query: 198  EVE---------------PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKL 242
            E                 P E   P     +  TLV S        E++T+S  P DSK 
Sbjct: 1137 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVS-------SEANTLSTTPVDSKT 1189

Query: 243  NLHLFKQFTQPRNTGGDSKTAPSSP 267
             +    + + P  T   +    S+P
Sbjct: 1190 QVATSTEASSPPPTAEVTSMPTSTP 1214



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 45/169 (26%), Positives = 71/169 (42%), Gaps = 23/169 (13%)

Query: 91   SPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQV-------LSTVPLAVSPGSSSSGP 143
            SP  A+G S+   P   P S+ T  L   PV    V       LST P+  +   ++S  
Sbjct: 3380 SPTTAEGTSI---PTSSP-SEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTE 3435

Query: 144  LASSPSVSSLSEQKTSSSSPLSSP------SKSPILSSSASTSTLSSAKPFMSLVKSLST 197
             +SSP+++  +   TS++S  S+P      S +P+ SS AST + +       +  S  T
Sbjct: 3436 ASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPT 3495

Query: 198  EVEPKES------PHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDS 240
               P  +         A       T +   +T  +  E+ T+S  P DS
Sbjct: 3496 NSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDS 3544



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 91/423 (21%), Positives = 151/423 (35%), Gaps = 68/423 (16%)

Query: 90   ASPVLADGLSVSQAPAILPVSKNTVKLLESPVP-------AAQVLSTVPLAVSPGSSSSG 142
            +SP  A+G S+  +     +S+    L  +PV         A  LST P+       S+ 
Sbjct: 1788 SSPTTAEGTSIPTST----LSEGMTPLTSTPVSHTLVANSEASTLSTTPV------DSNS 1837

Query: 143  PLASSPSVSSLSEQKTSSSSPLSSPSK----------SPILSSSASTSTLSSAKPFMSL- 191
            P+ +S +VSS       +S   S+PS+          S    +S+ T+TLS+     S  
Sbjct: 1838 PVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTP 1897

Query: 192  ------VKSLSTEVEPKESP-HPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNL 244
                  V S  T  +    P    R      T +   +T  +  E +T+S    D++  +
Sbjct: 1898 VTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPV 1957

Query: 245  HLFKQ-FTQPRNTGGDSKTAP-----SSPLTS--------PSDTRSFFKVPEMEAKIEDT 290
              + Q  + P    G S   P     S+PLTS         S   S      ++     T
Sbjct: 1958 TTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPAT 2017

Query: 291  KRRLSEVIYEPFQLLSKIIGEESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEE- 349
                +E    P       I   + S R   L+      + + S  G+  S      K + 
Sbjct: 2018 TS--TEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQV 2075

Query: 350  ----ECDSEGDGYGSDSNI--PRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVLE 403
                E  S     GS   I  P    P  T  P     + S + S+L    + ++S V+ 
Sbjct: 2076 TNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVIT 2135

Query: 404  KCSLSALVSKEDEEFCELYTEDFDLETEGES-KVDKLSDIPLKPEVLAEDGVVLDSEDEV 462
               +S+           + TE   ++T   S +   L+ +P+   V+A   +   S   V
Sbjct: 2136 STEVSS---------SPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPV 2186

Query: 463  DSA 465
            D++
Sbjct: 2187 DTS 2189



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 22/142 (15%)

Query: 95   ADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSL- 153
            A  LS +     +PV+ +T     S  P     +++P   SP S  + PLAS P  ++L 
Sbjct: 1118 ASTLSTTPVDTSIPVTTSTEA---SSSPTTAEGTSIP--TSPPSEGTTPLASMPVSTTLV 1172

Query: 154  --SEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES----PHP 207
              SE  T S++P+ S        +  +TST +S+ P  + V S+ T    + S      P
Sbjct: 1173 VSSEANTLSTTPVDS-------KTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMP 1225

Query: 208  ARHRHLMKTLVKSLST---DTS 226
             RH  +  +   +LST   DTS
Sbjct: 1226 VRHTPVASSEASTLSTSPVDTS 1247



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 58/239 (24%), Positives = 100/239 (41%), Gaps = 16/239 (6%)

Query: 107  LPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSS 166
            +PVS   V   E     A  LST P+  +   +SS   +SSP+   ++  + S+ S  SS
Sbjct: 3522 MPVSTTPVASSE-----ASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSS 3576

Query: 167  PSKSPILSSSASTSTLSSAKPFMSLVKS--LSTEVEPKESPHPARHRHLMKTLVKSLSTD 224
               + +LSS+  TS+ +S     S+ +S  ++T  +   +P P     L  +    +ST 
Sbjct: 3577 SLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTP 3636

Query: 225  TSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSP--LTSPSDTRSFFKVPE 282
             +     T S    ++     L    + P  T     ++P +P   T P  T S    P 
Sbjct: 3637 LTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPL 3696

Query: 283  MEAKIEDTKRRLSE--VIYEPFQLLSKIIGEESGSHRPKALSSSASELSNLSSLNGHLE 339
                +  T+   SE   +  P  + S  +   +     +A+SSSA+  S   S++  +E
Sbjct: 3697 TTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTST-----EAISSSATLDSTTMSVSMPME 3750



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 25/204 (12%)

Query: 89   AASPVLADGLSV---SQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLA 145
            ++SP+  +G S+   + +    P++   V        A   LST P+  S   ++S    
Sbjct: 2140 SSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEAR 2199

Query: 146  SSPSVSSLSEQKTSSSSPLSSP------SKSPILSSSASTSTLSSAKPFMSLVKSLSTEV 199
            SSP+ S  +   TS+ S  S+P      S  P+++S AST    SA P +     ++T  
Sbjct: 2200 SSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEAST---LSATP-VDTSTPVTTST 2255

Query: 200  EPKESPHPARHRHLMKTLVKSLSTD----------TSRQESDTVSYKPPDSKLNLHLFKQ 249
            E   SP  A    +  + +   +T            +  E  T+S  P DS        +
Sbjct: 2256 EATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTE 2315

Query: 250  FTQPRNT--GGDSKTAPSSPLTSP 271
             + P  T  G    T+ SS   +P
Sbjct: 2316 ASSPPPTAEGTSMPTSTSSEGNTP 2339



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 68/325 (20%), Positives = 126/325 (38%), Gaps = 24/325 (7%)

Query: 88  PAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASS 147
           P AS   ++  ++S  P        T     S  P A+V S      S GS+    ++ S
Sbjct: 463 PVAS---SEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVS 519

Query: 148 PSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHP 207
               + SE  T S++P+   + +P+ +SS ++S  SS  P  + + + +    P E   P
Sbjct: 520 TMPVASSEASTLSTTPVD--TSTPVTTSSEASS--SSTTPEGTSIPTST----PSEGSTP 571

Query: 208 ARHRHLMKTLV---KSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAP 264
             +  +   LV   ++ +T T+  +S+T      ++  +    +  + P +T  +  T  
Sbjct: 572 LTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTI 631

Query: 265 SS-------PLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHR 317
           +S         +S + T S   V         T+   S    E   + +    E S    
Sbjct: 632 TSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLT 691

Query: 318 PKALSS---SASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSNIPRSDHPKSTG 374
              +++   ++SE S LS+      +    S +     +  DG    ++ P       T 
Sbjct: 692 SMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTS 751

Query: 375 EPTREIELKSSQGSSLKDLGLKTSS 399
            P  +  L SS+ S+L    L TS+
Sbjct: 752 MPVSKTLLTSSEASTLSTTPLDTST 776



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 32/189 (16%)

Query: 98   LSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSL---S 154
            LS +      PV+ +T +   SP  A    +++P   S  S  + PL S+P   +L   S
Sbjct: 944  LSATPVDTSTPVTTST-EATSSPTTAEG--TSIP--TSTPSEGTTPLTSTPVSHTLVANS 998

Query: 155  EQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLM 214
            E  T S++P+ S       ++  +TST +S+ P  +   S+ T   P E   P     + 
Sbjct: 999  EASTLSTTPVDS-------NTPLTTSTEASSPPPTAEGTSMPTST-PSEGSTPLTRMPVS 1050

Query: 215  KTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAP-------SSP 267
             T+V S        E+ T+S  P D+   +  + Q     +T  D  + P       S+P
Sbjct: 1051 TTMVAS-------SETSTLSTTPADTSTPVTTYSQ-ASSSSTTADGTSMPTSTYSEGSTP 1102

Query: 268  LTS-PSDTR 275
            LTS P  TR
Sbjct: 1103 LTSVPVSTR 1111



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 50/180 (27%), Positives = 73/180 (40%), Gaps = 41/180 (22%)

Query: 89   AASPVLADGLSV--------SQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSS 140
            ++SP  A+G S+        S     +PVS  TV   E+       LST P   S   ++
Sbjct: 3260 SSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSET-----STLSTTPADTSTPVTT 3314

Query: 141  SGPLASSPSVSSLSEQKTSSSSPLSSP------SKSPILSSSAS--------------TS 180
                +SSP ++  +   TS+ S  S+P      S +P++SS AS              TS
Sbjct: 3315 YSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTS 3374

Query: 181  TLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDS 240
            T +S  P  +   S+ T   P E   P     +  T V S        E +T+S  P DS
Sbjct: 3375 TEASLSPTTAEGTSIPTS-SPSEGTTPLASMPVSTTPVVS-------SEVNTLSTTPVDS 3426



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 47/212 (22%), Positives = 98/212 (46%), Gaps = 37/212 (17%)

Query: 89   AASPVLADGLSV-SQAPAILPVSKNTVKLLESPVPAAQV--LSTVPLAVSPGSSSSGPLA 145
            ++SP  A+  S+ +  P+       ++ +  +PV +++   LST P+  S   ++S   +
Sbjct: 2789 SSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKAS 2848

Query: 146  SSPS--------VSSLSEQKTSSSS-PLSSPSKSPILSSSA---STSTLSSAKPFMSLVK 193
            SSP+        +S+ SE  T  +S P+S+   +P+ SS A   ST+ + ++ P  +  +
Sbjct: 2849 SSPTTAEGIVVPISTASEGSTLLTSIPVST---TPVASSEASTLSTTPVDTSIPVTTSTE 2905

Query: 194  SLSTEVEPKESPHPARHRHLMKTLVKSLSTDT---SRQESDTVSYKPPDSKLNLHLFKQF 250
              S+    + +  P      + T + S+   T   +  E+ T+S  P D++         
Sbjct: 2906 GSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTR--------- 2956

Query: 251  TQPRNTGGDSKTAP------SSPLTSPSDTRS 276
              P  T  ++ ++P      S P+++P + R+
Sbjct: 2957 -TPVTTSAEASSSPTTAEGTSMPISTPGERRT 2987



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 25/138 (18%)

Query: 86   AGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSS------ 139
            A  ++SP  A+G S+   P   P  + T      P+ +  V ST+P+A S  S+      
Sbjct: 2963 AEASSSPTTAEGTSM---PISTPGERRT------PLTSMSV-STMPVASSEASTLSRTPA 3012

Query: 140  -SSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS---- 194
             +S P+ +S   SS       +  P+S+PS+     +S   ST   A P  S + +    
Sbjct: 3013 DTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD 3072

Query: 195  ----LSTEVEPKESPHPA 208
                + T  E   SP PA
Sbjct: 3073 SNSPVVTSTEVSSSPTPA 3090



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 7/101 (6%)

Query: 98  LSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQK 157
           L+   A  +   S   + LL +PV  +      P+ +S  +SSS   A  PS+S  +   
Sbjct: 218 LTSMPASTMKVASSEAITLLTTPVEIS-----TPVTISAQASSSPTTAEGPSLS--NSAP 270

Query: 158 TSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTE 198
           +  S+PL+    S +L  S+  STLS+     ++    STE
Sbjct: 271 SGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTE 311



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 50/215 (23%), Positives = 82/215 (38%), Gaps = 42/215 (19%)

Query: 91   SPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQV-LSTVPLAVSPGSS-------SSG 142
            SPV+      S A +    S  T    E   P   + +ST PLA S  S+       +S 
Sbjct: 2544 SPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSI 2603

Query: 143  PLASSPSVSSLSEQKTSSSSPLSSPSK------------SPILSSSASTSTLSSAKPFMS 190
            P+ +S   SS       +S P+S+PS+             P+ SS AST + +       
Sbjct: 2604 PVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTL 2663

Query: 191  LVKSLSTEVEPKESPHPAR------HRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNL 244
            +  S  T   P  +   +        R    T +   +T  +  E+ T+S  P D+    
Sbjct: 2664 VTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDT---- 2719

Query: 245  HLFKQFTQPRNTGGDSKTAP------SSPLTSPSD 273
                  + P  T  ++ ++P      S  +++PSD
Sbjct: 2720 ------STPVTTSAEASSSPTTAEGTSMRISTPSD 2748



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 45/193 (23%), Positives = 80/193 (41%), Gaps = 21/193 (10%)

Query: 90   ASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPS 149
            ++PV+     VS +P      + T   + +P   +  L+T+P++ +  +SS G   S+PS
Sbjct: 3663 STPVITS-TQVSSSPV---TPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPS 3718

Query: 150  VSS-----LSEQKTSSSSPLSSPSKS---PILSSSASTSTLSSAKPFMSLVKSLSTEVEP 201
            V +      S +  SSS+ L S + S   P+  S+  T+ L S  P     +S +  +  
Sbjct: 3719 VVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSI-- 3776

Query: 202  KESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSK 261
                 P+ +  +  T     S+  +  E  T       S+ +  L      P +    S+
Sbjct: 3777 -----PSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSE 3831

Query: 262  TAPSSPLTSPSDT 274
             +  S  T P DT
Sbjct: 3832 ASTLS--TPPGDT 3842



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 49/203 (24%), Positives = 83/203 (40%), Gaps = 25/203 (12%)

Query: 90   ASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQV-------LSTVPLAVSPGSSSSG 142
            +SP  A+G S+  +     +S+ T  L   PV    V       LST P+  +   ++S 
Sbjct: 2259 SSPTTAEGTSIPTST----LSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTST 2314

Query: 143  PLASSPSVSSLSEQKTSSSS----PLSSPSKSPILSSSASTSTLS-----SAKPFMSLVK 193
              +S P  +  +   TS+SS    PL+    S  + +S  TSTLS     ++ P  +  +
Sbjct: 2315 EASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQ 2374

Query: 194  SLSTEVEPKESPHPARHRHLMKTLVKSLSTDTS---RQESDTVSYKPPDSKLNLHLFKQF 250
            + S+     ++  P        T + S+   T      E+ T S  P D+   +    + 
Sbjct: 2375 AGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEA 2434

Query: 251  TQPRNT--GGDSKTAPSSPLTSP 271
            +    T  G    T+P S  T+P
Sbjct: 2435 SSSPTTAEGTSIPTSPPSEGTTP 2457



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 43/197 (21%), Positives = 82/197 (41%), Gaps = 33/197 (16%)

Query: 89   AASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQV-------LSTVPLAVSPGSSSS 141
            ++ P  A+G S+  + +    S+    L   PV    V       LST P   S   ++ 
Sbjct: 2317 SSPPPTAEGTSMPTSTS----SEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTY 2372

Query: 142  GPLASSPSVSSLSEQKTSSSSPLSSP------SKSPILSSSA---STSTLSSAKPFMSLV 192
                SSP+ +  +   TS+ S  S+P      S  P++SS A   ST+ + ++ P  +  
Sbjct: 2373 SQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTST 2432

Query: 193  KSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTS---RQESDTVSYKPPDSKLNLHLFKQ 249
            ++ S+    + +  P        T + S+   T+     E+ T+S  P D+         
Sbjct: 2433 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDT--------- 2483

Query: 250  FTQPRNTGGDSKTAPSS 266
             + P  T  ++ ++P++
Sbjct: 2484 -STPMTTSTEASSSPTT 2499



 Score = 34.3 bits (77), Expect = 0.69
 Identities = 40/160 (25%), Positives = 63/160 (39%), Gaps = 33/160 (20%)

Query: 117  LESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSS 176
            L +  P A + ST PL  S   + S   AS+P++   +    S  +  S+P  +  + S+
Sbjct: 3885 LPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPST 3944

Query: 177  ASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYK 236
              TS  S+A  F +   ++ST V                     L+T ++   S T S+ 
Sbjct: 3945 PVTS--STADVFPATTGAVSTPV----------------ITSTELNTPSTSSSSTTTSFS 3986

Query: 237  PPDSKLNLHLFKQFTQPRNTGG------DSKTAPSSPLTS 270
                       K+FT P  T           TAPS+P T+
Sbjct: 3987 TT---------KEFTTPAMTTAAPLTYVTMSTAPSTPRTT 4017



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 49/210 (23%), Positives = 81/210 (38%), Gaps = 37/210 (17%)

Query: 90   ASPVLADGLSVSQAPAILPVSKNTVKLLESPVPA-------AQVLSTVPLAVSPGSSSSG 142
            +SP  ++G S+  +      S+ T  L   PV         A  LS  P+  S   ++S 
Sbjct: 1376 SSPTTSEGTSMPNSNP----SEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSA 1431

Query: 143  PLASSPSVSSLSEQKTSSSSPLSSPSKS------PILSSSASTSTLSSAKPFMSLVKSLS 196
               SSP+ +      TS+ S   +P KS      P+ +S AST + +       +V S +
Sbjct: 1432 EATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTA 1491

Query: 197  TEVEPKESPHPARHRHL----------MKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHL 246
                   SP PA    +            T +   +T  +  E +++S  P  +   +  
Sbjct: 1492 V----SSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTT 1547

Query: 247  FKQ-FTQPRNTGGDSK-----TAPSSPLTS 270
            + Q  + P    G S      +  S+PLTS
Sbjct: 1548 YSQASSSPTTADGTSMQTSTYSEGSTPLTS 1577



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 42/195 (21%), Positives = 77/195 (39%), Gaps = 6/195 (3%)

Query: 89   AASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSP 148
            ++SP   +G +          S     +L SP+          L+  PG +S+  L S+ 
Sbjct: 3792 SSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTK 3851

Query: 149  SVS-SLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS----LSTEVEPKE 203
            + S S+  + T+    ++S   +P+ +   ST TL ++ P  S+  +     ST   P  
Sbjct: 3852 AGSFSIPAEVTTIRISITSERSTPLTTLLVST-TLPTSFPGASIASTPPLDTSTTFTPST 3910

Query: 204  SPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTA 263
                     +  T+  S+ T+ S   +       P +     +F   T   +T   + T 
Sbjct: 3911 DTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTE 3970

Query: 264  PSSPLTSPSDTRSFF 278
             ++P TS S T + F
Sbjct: 3971 LNTPSTSSSSTTTSF 3985



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 51/211 (24%), Positives = 88/211 (41%), Gaps = 30/211 (14%)

Query: 90  ASPVLADGLSVSQA-PAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSP 148
           +SP   +G  V  + P+   +S     +  +P+P+ +  +++   V      S PL +S 
Sbjct: 137 SSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVD----MSTPLTTST 192

Query: 149 SVSSLSEQKTSSSSPLSSPSK--SPILSSSASTSTLSSAKPFMSLVK--SLSTEV----E 200
             SS      S++ P S+ S+  +P+ S  AST  ++S++    L     +ST V    +
Sbjct: 193 QASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQ 252

Query: 201 PKESPHPARHRHLMKTLVKSLSTDTSR----------QESDTVSYKPPDSKLN-LHLFKQ 249
              SP  A    L  +     ST  +R           E+ T+S  P  + +  +   + 
Sbjct: 253 ASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEA 312

Query: 250 FTQPRNTGGDS-----KTAPSSPLTS-PSDT 274
            + P    G S      T  S+PLTS P+ T
Sbjct: 313 SSSPTTAEGTSIPTSTYTEGSTPLTSTPAST 343



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 8/135 (5%)

Query: 95   ADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLS 154
            A  LS +   +  P++ +T     SP P A+  S      S GS+    +  S ++ + S
Sbjct: 1000 ASTLSTTPVDSNTPLTTSTEA--SSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASS 1057

Query: 155  EQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLM 214
            E  T S++P  + +     S ++S+ST +      S+  S  +E     +  P   R ++
Sbjct: 1058 ETSTLSTTPADTSTPVTTYSQASSSSTTADG---TSMPTSTYSEGSTPLTSVPVSTRLVV 1114

Query: 215  KTLVKSLST---DTS 226
             +   +LST   DTS
Sbjct: 1115 SSEASTLSTTPVDTS 1129



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 13/89 (14%)

Query: 100  VSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTS 159
            VS    I+PVS  +V + E     A   ST+P+       +S P+ +S  VSS       
Sbjct: 3633 VSTPLTIMPVSTTSVTISE-----AGTASTLPV------DTSTPVITSTQVSSSPVTPEG 3681

Query: 160  SSSPLSSPSK--SPILSSSASTSTLSSAK 186
            ++ P+ +PS+  +P+ +   ST+ ++S++
Sbjct: 3682 TTMPIWTPSEGSTPLTTMPVSTTRVTSSE 3710


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 44/138 (31%), Positives = 64/138 (46%), Gaps = 9/138 (6%)

Query: 107  LPVSKNT-VKLLESPVPAAQ--VLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSP 163
            LPV     +K + SP PA +  V    P   +P        +SS S SS S   +SSSS 
Sbjct: 2568 LPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS 2627

Query: 164  LSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLST 223
             SS S S   SSS+S+S+ SS  P     ++L     PK+ P   R     +  + SL  
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL-- 2685

Query: 224  DTSRQESDTVSYKPPDSK 241
                ++S ++SY P + +
Sbjct: 2686 ----RDSRSLSYSPVERR 2699



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 60/254 (23%), Positives = 89/254 (35%), Gaps = 30/254 (11%)

Query: 116  LLESPVPAAQVLSTVPLAVSPGSSSSGPLAS--------SPSVSSLSEQKTSSSSPLSSP 167
            +L  P P            S G+     LA+        S S SS S   +SSSS  SS 
Sbjct: 2493 MLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSS 2552

Query: 168  SKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES--------PHPARHRHLMKTLVK 219
            S S   SSS S  +    +P ++L +  S    PKE+        P PA+ +    +   
Sbjct: 2553 SSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSS 2612

Query: 220  SLSTDTSRQESDTVSYKPPDSKLNLHLFKQFT-----QPRNTGGDSKTAPSSPLTSPSDT 274
            S S+ +S   S + S     S  +       +      P   G  +   P+SP   P   
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE 2672

Query: 275  RSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRPKALSSSASELSNLSSL 334
            R          K  D+ R    + Y P +         S    P+   SS+SE  +    
Sbjct: 2673 RR----SRSPRKPIDSLRDSRSLSYSPVER-----RRPSPQPSPRDQQSSSSERGSRRGQ 2723

Query: 335  NGHLESNNNYSIKE 348
             G   S ++   +E
Sbjct: 2724 RGDSRSPSHKRRRE 2737



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 43/149 (28%), Positives = 63/149 (42%), Gaps = 9/149 (6%)

Query: 97   GLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSS----SSGPLASSPSVSS 152
            G S+S + +  P  K+   L++S   +  + + V  +  PG S    SS  L      S 
Sbjct: 1006 GPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP 1065

Query: 153  LSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRH 212
                 TSS     S S+SP L S + T    S K   S   S  TE+  +      R   
Sbjct: 1066 DHRSDTSSPEVRQSHSESPSLQSKSQT----SPKGGRSRSSSPVTELASRSPIRQDRGEF 1121

Query: 213  LMKTLVKS-LSTDTSRQESDTVSYKPPDS 240
                ++KS +S + SR +SD+ SY   DS
Sbjct: 1122 SASPMLKSGMSPEQSRFQSDSSSYPTVDS 1150



 Score = 37.4 bits (85), Expect = 0.081
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 2/79 (2%)

Query: 135 SPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS 194
           SP   ++ PL+  P         T   SP  SP K P   SS+S S+  S +P      +
Sbjct: 377 SPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLP--QSSSSESSPPSPQPTKVSRHA 434

Query: 195 LSTEVEPKESPHPARHRHL 213
            S+   PK +P P  HR +
Sbjct: 435 SSSPESPKPAPAPGSHREI 453



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 63/320 (19%), Positives = 115/320 (35%), Gaps = 24/320 (7%)

Query: 79   PQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGS 138
            P   ++      SP L D       P+    S+ T +   +P P++++      ++ P +
Sbjct: 2386 PLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSE--RAPSPSSRMGQAPSQSLLPPA 2443

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTE 198
                    SP  S+ S+Q     +  +  + S  LSS A  +T SSA     ++   +  
Sbjct: 2444 QDQ---PRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPG 2500

Query: 199  VEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGG 258
            V   +   P              ++  ++Q S   + +P   + +       +   ++  
Sbjct: 2501 VPHSDVGEPP-------------ASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSS 2547

Query: 259  DSKTAPSSPLTSPSDTR--SFFKVPEMEAK-IEDTKRRLSEVIYE---PFQLLSKIIGEE 312
             S ++ SS  +S SD+   S    PE+  K +        E + E   P    +K     
Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRS 2607

Query: 313  SGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSNIPRSDHPKS 372
            S S    + SSS+S  S+ SS +    S+++ S       S          +P+   PK 
Sbjct: 2608 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK 2667

Query: 373  TGEPTREIELKSSQGSSLKD 392
                 R          SL+D
Sbjct: 2668 PPPGERRSRSPRKPIDSLRD 2687



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 45/187 (24%), Positives = 66/187 (35%), Gaps = 25/187 (13%)

Query: 118  ESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSA 177
            ES V    V  T PL     S SS  L   PS S     ++ SS    + +++P+   S 
Sbjct: 1520 ESSVDQKTVART-PLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSR 1578

Query: 178  STSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKP 237
            S S               S EV+ K    P R R      VK       R +S + S   
Sbjct: 1579 SGS---------------SPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPE 1623

Query: 238  PDSKLNLHLFKQFTQPRNTGG---------DSKTAPSSPLTSPSDTRSFFKVPEMEAKIE 288
            P +     L ++     ++ G          ++++P  P  S +  R     PE + K  
Sbjct: 1624 PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSR 1683

Query: 289  DTKRRLS 295
               RR S
Sbjct: 1684 TPPRRRS 1690



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 64/317 (20%), Positives = 112/317 (35%), Gaps = 65/317 (20%)

Query: 79   PQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGS 138
            P     P  PA++ ++    + + AP  +  S+    L  + + +A++   +        
Sbjct: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPAL-------- 2375

Query: 139  SSSGPLASSPSVSSLSEQKTS--SSSPLSSPSKSPILSSSASTSTLSSAK---PFMSLVK 193
              SG   +SP V   + ++ S  +S PL   ++S    S+ S S ++S +   P   + +
Sbjct: 2376 --SGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQ 2433

Query: 194  SLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQP 253
            + S  + P     P       ++ V S  +D SR                  L  Q T  
Sbjct: 2434 APSQSLLPPAQDQP-------RSPVPSAFSDQSRC-----------------LIAQTTPV 2469

Query: 254  RNTGGDSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEES 313
              +   S  A ++  +S  D      VP       D        + EP           +
Sbjct: 2470 AGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD--------VGEP--------PAST 2513

Query: 314  GSHRPKAL----------SSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSN 363
            G+ +P AL          SSS+S  S+ SS +    S+++ S      DSEG        
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573

Query: 364  IPRSDHPKSTGEPTREI 380
            +     P  T  P   +
Sbjct: 2574 VALKRVPSPTPAPKEAV 2590



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 12/188 (6%)

Query: 141 SGPLASSPSVSSLSEQKT-SSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLS-TE 198
           SG  +   + S  S++++ S+SSP    S+     S + +S  S AK  +SL +SLS + 
Sbjct: 724 SGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSS 783

Query: 199 VEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGG 258
             PK+       R    +      + T  + S + S  PP  K         T  R +  
Sbjct: 784 PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSK-------TPSRQSHS 836

Query: 259 DSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEE--SGSH 316
            S   P     +P    S       E  +   +R   E   +P +L S+       SGS 
Sbjct: 837 SSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDP-ELKSRTPSRHSCSGSS 895

Query: 317 RPKALSSS 324
            P+  SS+
Sbjct: 896 PPRVKSST 903



 Score = 30.4 bits (67), Expect = 10.0
 Identities = 35/156 (22%), Positives = 54/156 (34%), Gaps = 5/156 (3%)

Query: 656 SEEKPPAEGSEDPKKPPRPQEGTRSSQRDQILYLFGRTGREKEEWFRRFILASKLKSEIK 715
           S  + PA       + PR     R   R + L   GR+     +   R   +S+ K++ +
Sbjct: 681 SRSRTPARRGRSRSRTPR-----RGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735

Query: 716 KSSGVSGGKPAPVFLAPGLLPAHSRHNSPSGHLTHSRSSSKGSVEEIMSQPKQKELAGSV 775
            S   S    +P      +    SR  S       SR S + S+      PKQK      
Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR 795

Query: 776 RQKMLLDYSVYMGRCVPQESRSPQRSPLQSAESSPT 811
           R +          R  P+ SRS    P +    +P+
Sbjct: 796 RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS 831


>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
           sapiens]
          Length = 1135

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 69/266 (25%), Positives = 104/266 (39%), Gaps = 51/266 (19%)

Query: 85  PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
           PA P   P +A     S  P+ILP SK+       P P A   +    A SP   +S P 
Sbjct: 749 PAAPPKRPAVA-----SARPSILP-SKDV-----KPKPIADAKAPEKRA-SPSKPASAPA 796

Query: 145 ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES 204
           + S S S+ +  KT++++ ++S        SS S STL   KP      ++ TE +P E 
Sbjct: 797 SRSGSKSTQTVAKTTTAAAVASTG-----PSSRSPSTLLPKKP-----TAIKTEGKPAE- 845

Query: 205 PHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAP 264
                   + K   KS+  D SR +S + S             K+ T    T   +   P
Sbjct: 846 --------VKKMTAKSVPADLSRPKSTSTS-----------SMKKTTTLSGTAPAAGVVP 886

Query: 265 S----SPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPF-----QLLSKIIGEESGS 315
           S    +P+ S   T  F       AK   T  RLS +           + SK+   E+  
Sbjct: 887 SRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIK 946

Query: 316 HRPKALSSSASELSNLSSLNGHLESN 341
           H+P    +   + +  ++     ESN
Sbjct: 947 HQPGGGRAKVEKKTEAAATTRKPESN 972


>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
           sapiens]
          Length = 887

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 69/266 (25%), Positives = 104/266 (39%), Gaps = 51/266 (19%)

Query: 85  PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
           PA P   P +A     S  P+ILP SK+       P P A   +    A SP   +S P 
Sbjct: 484 PAAPPKRPAVA-----SARPSILP-SKDV-----KPKPIADAKAPEKRA-SPSKPASAPA 531

Query: 145 ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES 204
           + S S S+ +  KT++++ ++S        SS S STL   KP      ++ TE +P E 
Sbjct: 532 SRSGSKSTQTVAKTTTAAAVASTG-----PSSRSPSTLLPKKP-----TAIKTEGKPAE- 580

Query: 205 PHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAP 264
                   + K   KS+  D SR +S + S             K+ T    T   +   P
Sbjct: 581 --------VKKMTAKSVPADLSRPKSTSTS-----------SMKKTTTLSGTAPAAGVVP 621

Query: 265 S----SPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPF-----QLLSKIIGEESGS 315
           S    +P+ S   T  F       AK   T  RLS +           + SK+   E+  
Sbjct: 622 SRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIK 681

Query: 316 HRPKALSSSASELSNLSSLNGHLESN 341
           H+P    +   + +  ++     ESN
Sbjct: 682 HQPGGGRAKVEKKTEAAATTRKPESN 707



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 12/198 (6%)

Query: 642 QDDFMSKAQTDKETSEEKPPAEG-SEDPKKPPRPQEG-TRSSQRDQILYLFGRTGREKEE 699
           +D  +   Q   E SE K P EG  ED  +   P +G  R ++   +  L  ++  +++E
Sbjct: 334 KDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQE 393

Query: 700 WFRRFILASKLKSEIKKSSGVSGGKPAPVFLAPG--LLPAHSRHNSPSGHLTHSRSSSKG 757
             ++   A   + E  +   V  G    +   P   L P+  +   P      +++S+  
Sbjct: 394 RHKQLKSAGIARPE--EGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSK 451

Query: 758 SVEEIMSQPKQ--KELAGSVRQKMLLDYSVYMGRCVPQE----SRSPQRSPLQSAESSPT 811
           +  +  S PKQ      G + +K +   S  +    P+     S  P   P +  +  P 
Sbjct: 452 AKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI 511

Query: 812 AGKKLPEVPPSEEEEQEA 829
           A  K PE   S  +   A
Sbjct: 512 ADAKAPEKRASPSKPASA 529


>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo
           sapiens]
          Length = 1152

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 69/266 (25%), Positives = 104/266 (39%), Gaps = 51/266 (19%)

Query: 85  PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
           PA P   P +A     S  P+ILP SK+       P P A   +    A SP   +S P 
Sbjct: 749 PAAPPKRPAVA-----SARPSILP-SKDV-----KPKPIADAKAPEKRA-SPSKPASAPA 796

Query: 145 ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES 204
           + S S S+ +  KT++++ ++S        SS S STL   KP      ++ TE +P E 
Sbjct: 797 SRSGSKSTQTVAKTTTAAAVASTG-----PSSRSPSTLLPKKP-----TAIKTEGKPAE- 845

Query: 205 PHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAP 264
                   + K   KS+  D SR +S + S             K+ T    T   +   P
Sbjct: 846 --------VKKMTAKSVPADLSRPKSTSTS-----------SMKKTTTLSGTAPAAGVVP 886

Query: 265 S----SPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPF-----QLLSKIIGEESGS 315
           S    +P+ S   T  F       AK   T  RLS +           + SK+   E+  
Sbjct: 887 SRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIK 946

Query: 316 HRPKALSSSASELSNLSSLNGHLESN 341
           H+P    +   + +  ++     ESN
Sbjct: 947 HQPGGGRAKVEKKTEAAATTRKPESN 972


>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
          Length = 437

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 70/323 (21%), Positives = 118/323 (36%), Gaps = 24/323 (7%)

Query: 98  LSVSQAPAILPVSKNTVKLLESPV-PAAQVLSTVP-LAVSPGSSSSGPLASSPSVSSLSE 155
           L+V+ A A+  ++  +VK  E+ V P+A  +ST P L+  PG S+           S S+
Sbjct: 10  LNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSK 69

Query: 156 QKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMK 215
               + +P  +P+KS   + +   S+  S     +   S S      ++   +  +   +
Sbjct: 70  SSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPE 129

Query: 216 TLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTSPSDTR 275
                 ST  S  E+ T    P DS            P  +G ++KT   SP  S S+ +
Sbjct: 130 LQTPKDSTGKSGAEAQT----PEDS------------PNRSGAEAKTQKDSPSKSGSEAQ 173

Query: 276 SFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRPKALSSSASELSNLSSLN 335
           +   VP        T +  S       Q    +  +     +     S+ S       ++
Sbjct: 174 TTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPID 233

Query: 336 GHLESNNNYSIKEEECDSEGDGYGSDSNIPRSDHPKSTGEPTREIELKSSQGSSLKDLG- 394
           G  +S       EE+   +           R DH K    P+   EL  +  + L D G 
Sbjct: 234 GPSKSG-----AEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGK 288

Query: 395 LKTSSLVLEKCSLSALVSKEDEE 417
           L   +   E    + L+S   EE
Sbjct: 289 LSPHAFKTESGEETDLISPPQEE 311


>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
          Length = 2365

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 80/338 (23%), Positives = 130/338 (38%), Gaps = 60/338 (17%)

Query: 119  SPVPAAQV-LSTVPLAVSPGSSSSGP---------LASSPSVS-------SLSEQKTSSS 161
            SP+ +  V L+  PLA SP S+ S P          +SS +VS       S+S   TS  
Sbjct: 1289 SPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCE 1348

Query: 162  SPLSSPSKSPILSSSASTSTLSSAK-----PFMSLVKSLSTEVEPKESPHPARHRHLMKT 216
            S   S S   + S ++ST  ++S+K     PF+      +T  E   S   A  +    T
Sbjct: 1349 SIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRST 1408

Query: 217  LVKSLSTDTSRQESDT----VSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSP----- 267
            L +   +D     +      + Y P          K++ +  + GG   TA +SP     
Sbjct: 1409 LPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 1468

Query: 268  -LTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRP------KA 320
             +TSPS TR  F   ++ +    T+  LS     P  L +  +    G + P      + 
Sbjct: 1469 SVTSPSGTR--FNFSQLASPTTVTQMSLS----NPTMLRTHSLSNADGQYDPYTDSRFRN 1522

Query: 321  LSSSASELSNLSSLNGHL----------------ESNNNYSIKEEECDSEGDGYGSDSNI 364
             S S  E S   S +G                   +++ YS  EE+C SE      + + 
Sbjct: 1523 SSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDA 1582

Query: 365  PRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVL 402
             +      T + T    L ++   SL ++ ++  SL +
Sbjct: 1583 SQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTM 1620



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 51/194 (26%), Positives = 78/194 (40%), Gaps = 22/194 (11%)

Query: 12  TTDMPKPSAPKVHV----QRSVSRDTIAIHFSASGEEEEEE---EEEFREYFEEGLDDQS 64
           TT  P  S+PK+ +    QR+ SR       S  G E+E+E    E+ +E  ++     S
Sbjct: 386 TTVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRAS 445

Query: 65  IVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGL----------SVSQAPAILPVSKNTV 114
           +   L+ KE+   +P     P  P  S  +A  +              AP+   + K  +
Sbjct: 446 VTERLDLKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGM 505

Query: 115 KLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSP--- 171
           K +    P+A   S        G  SSG     P +       +SSSS  SS  K P   
Sbjct: 506 KSMPGKSPSAPAPSKEGERSRSGKLSSGLPQQKPQLD--GRHSSSSSSLASSEGKGPGGT 563

Query: 172 ILSSSASTSTLSSA 185
            L+ S S+ T+S +
Sbjct: 564 TLNHSISSQTVSGS 577


>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
          Length = 2432

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 80/338 (23%), Positives = 130/338 (38%), Gaps = 60/338 (17%)

Query: 119  SPVPAAQV-LSTVPLAVSPGSSSSGP---------LASSPSVS-------SLSEQKTSSS 161
            SP+ +  V L+  PLA SP S+ S P          +SS +VS       S+S   TS  
Sbjct: 1353 SPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCE 1412

Query: 162  SPLSSPSKSPILSSSASTSTLSSAK-----PFMSLVKSLSTEVEPKESPHPARHRHLMKT 216
            S   S S   + S ++ST  ++S+K     PF+      +T  E   S   A  +    T
Sbjct: 1413 SIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRST 1472

Query: 217  LVKSLSTDTSRQESDT----VSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSP----- 267
            L +   +D     +      + Y P          K++ +  + GG   TA +SP     
Sbjct: 1473 LPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 1532

Query: 268  -LTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRP------KA 320
             +TSPS TR  F   ++ +    T+  LS     P  L +  +    G + P      + 
Sbjct: 1533 SVTSPSGTR--FNFSQLASPTTVTQMSLS----NPTMLRTHSLSNADGQYDPYTDSRFRN 1586

Query: 321  LSSSASELSNLSSLNGHL----------------ESNNNYSIKEEECDSEGDGYGSDSNI 364
             S S  E S   S +G                   +++ YS  EE+C SE      + + 
Sbjct: 1587 SSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDA 1646

Query: 365  PRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVL 402
             +      T + T    L ++   SL ++ ++  SL +
Sbjct: 1647 SQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTM 1684



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 51/194 (26%), Positives = 78/194 (40%), Gaps = 22/194 (11%)

Query: 12  TTDMPKPSAPKVHV----QRSVSRDTIAIHFSASGEEEEEE---EEEFREYFEEGLDDQS 64
           TT  P  S+PK+ +    QR+ SR       S  G E+E+E    E+ +E  ++     S
Sbjct: 450 TTVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRAS 509

Query: 65  IVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGL----------SVSQAPAILPVSKNTV 114
           +   L+ KE+   +P     P  P  S  +A  +              AP+   + K  +
Sbjct: 510 VTERLDLKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGM 569

Query: 115 KLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSP--- 171
           K +    P+A   S        G  SSG     P +       +SSSS  SS  K P   
Sbjct: 570 KSMPGKSPSAPAPSKEGERSRSGKLSSGLPQQKPQLD--GRHSSSSSSLASSEGKGPGGT 627

Query: 172 ILSSSASTSTLSSA 185
            L+ S S+ T+S +
Sbjct: 628 TLNHSISSQTVSGS 641


>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
          Length = 2429

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 80/338 (23%), Positives = 130/338 (38%), Gaps = 60/338 (17%)

Query: 119  SPVPAAQV-LSTVPLAVSPGSSSSGP---------LASSPSVS-------SLSEQKTSSS 161
            SP+ +  V L+  PLA SP S+ S P          +SS +VS       S+S   TS  
Sbjct: 1353 SPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCE 1412

Query: 162  SPLSSPSKSPILSSSASTSTLSSAK-----PFMSLVKSLSTEVEPKESPHPARHRHLMKT 216
            S   S S   + S ++ST  ++S+K     PF+      +T  E   S   A  +    T
Sbjct: 1413 SIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRST 1472

Query: 217  LVKSLSTDTSRQESDT----VSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSP----- 267
            L +   +D     +      + Y P          K++ +  + GG   TA +SP     
Sbjct: 1473 LPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 1532

Query: 268  -LTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRP------KA 320
             +TSPS TR  F   ++ +    T+  LS     P  L +  +    G + P      + 
Sbjct: 1533 SVTSPSGTR--FNFSQLASPTTVTQMSLS----NPTMLRTHSLSNADGQYDPYTDSRFRN 1586

Query: 321  LSSSASELSNLSSLNGHL----------------ESNNNYSIKEEECDSEGDGYGSDSNI 364
             S S  E S   S +G                   +++ YS  EE+C SE      + + 
Sbjct: 1587 SSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDA 1646

Query: 365  PRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVL 402
             +      T + T    L ++   SL ++ ++  SL +
Sbjct: 1647 SQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTM 1684



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 51/194 (26%), Positives = 78/194 (40%), Gaps = 22/194 (11%)

Query: 12  TTDMPKPSAPKVHV----QRSVSRDTIAIHFSASGEEEEEE---EEEFREYFEEGLDDQS 64
           TT  P  S+PK+ +    QR+ SR       S  G E+E+E    E+ +E  ++     S
Sbjct: 450 TTVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRAS 509

Query: 65  IVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGL----------SVSQAPAILPVSKNTV 114
           +   L+ KE+   +P     P  P  S  +A  +              AP+   + K  +
Sbjct: 510 VTERLDLKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGM 569

Query: 115 KLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSP--- 171
           K +    P+A   S        G  SSG     P +       +SSSS  SS  K P   
Sbjct: 570 KSMPGKSPSAPAPSKEGERSRSGKLSSGLPQQKPQLD--GRHSSSSSSLASSEGKGPGGT 627

Query: 172 ILSSSASTSTLSSA 185
            L+ S S+ T+S +
Sbjct: 628 TLNHSISSQTVSGS 641


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 15/149 (10%)

Query: 67   TGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQV 126
            TG++  +     P +   P  P+ S  +    S      + PV  +T     +PVPA+ +
Sbjct: 1735 TGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPAST----SAPVPASTL 1790

Query: 127  L-----STVPLAVSPGS--SSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPIL---SSS 176
                  ++ P+  SP +  S+S  +++S   S+ +   TSSS+P S+P+ +PIL   S+ 
Sbjct: 1791 APVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTP 1850

Query: 177  ASTSTLSSAKPFMSLVKSLSTEVEPKESP 205
            AS + L+SA     L  +L++   P  +P
Sbjct: 1851 ASVTILASAS-IPILASALASTSAPTPAP 1878



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 41/173 (23%), Positives = 69/173 (39%), Gaps = 14/173 (8%)

Query: 77   LEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSP 136
            L P +    A   ASP+     S S + ++ P S +   +  S  PA+    T P+  S 
Sbjct: 1790 LAPVLASTSAPVPASPLAPVSASASVSASV-PASTSAAAITSSSAPASAPAPT-PILASV 1847

Query: 137  GSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKS---------PILSSSASTSTLSSAKP 187
             + +S  + +S S+  L+    S+S+P  +P+ S         P + +SA T+++  A  
Sbjct: 1848 STPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPA 1907

Query: 188  FMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDS 240
              S      T   P  +P+PA                   Q +   S +PP S
Sbjct: 1908 SASAPAPAPT---PVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPS 1957


>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
           sapiens]
          Length = 817

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 70/265 (26%), Positives = 105/265 (39%), Gaps = 55/265 (20%)

Query: 85  PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
           PA P   P +A     S  P+ILP SK+       P P A   +    A SP   +S P 
Sbjct: 484 PAAPPKRPAVA-----SARPSILP-SKDV-----KPKPIADAKAPEKRA-SPSKPASAPA 531

Query: 145 ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES 204
           + S S S+ +  KT++++ ++S        SS S STL   KP      ++ TE +P E 
Sbjct: 532 SRSGSKSTQTVAKTTTAAAVASTG-----PSSRSPSTLLPKKP-----TAIKTEGKPAE- 580

Query: 205 PHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAP 264
                   + K   KS+  D SR +S + S             K+ T    T   +   P
Sbjct: 581 --------VKKMTAKSVPADLSRPKSTSTS-----------SMKKTTTLSGTAPAAGVVP 621

Query: 265 S----SPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPF-----QLLSKIIGEESGS 315
           S    +P+ S   T  F       AK   T  RLS +           + SK+   E+  
Sbjct: 622 SRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIK 681

Query: 316 HRPKA----LSSSASELSNLSSLNG 336
           H+P      + +   ++S +SS  G
Sbjct: 682 HQPGGGRVQIQNKKVDISKVSSKCG 706



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 12/198 (6%)

Query: 642 QDDFMSKAQTDKETSEEKPPAEG-SEDPKKPPRPQEG-TRSSQRDQILYLFGRTGREKEE 699
           +D  +   Q   E SE K P EG  ED  +   P +G  R ++   +  L  ++  +++E
Sbjct: 334 KDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQE 393

Query: 700 WFRRFILASKLKSEIKKSSGVSGGKPAPVFLAPG--LLPAHSRHNSPSGHLTHSRSSSKG 757
             ++   A   + E  +   V  G    +   P   L P+  +   P      +++S+  
Sbjct: 394 RHKQLKSAGIARPE--EGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSK 451

Query: 758 SVEEIMSQPKQ--KELAGSVRQKMLLDYSVYMGRCVPQE----SRSPQRSPLQSAESSPT 811
           +  +  S PKQ      G + +K +   S  +    P+     S  P   P +  +  P 
Sbjct: 452 AKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI 511

Query: 812 AGKKLPEVPPSEEEEQEA 829
           A  K PE   S  +   A
Sbjct: 512 ADAKAPEKRASPSKPASA 529


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 31/66 (46%), Positives = 39/66 (59%)

Query: 133  AVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLV 192
            A SP SSSS   +SS S SS S   +SSSS  SS S S   SSS+S+S+ SS+    S  
Sbjct: 2609 AASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668

Query: 193  KSLSTE 198
             S +T+
Sbjct: 2669 SSSTTD 2674



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 3/86 (3%)

Query: 123  AAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTL 182
            AA   +  P + S  SSSS   +SS S SS S   +SSSS  SS S S   SSS+S+S+ 
Sbjct: 2604 AASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2663

Query: 183  SSAKPFMSLV---KSLSTEVEPKESP 205
            SS+    S      S S++ E   +P
Sbjct: 2664 SSSSSSSSTTDEDSSCSSDDEAAPAP 2689



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 29/73 (39%), Positives = 40/73 (54%)

Query: 135  SPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS 194
            S  SSSS   +SS S SS S   +SSSS  SS S S   SSS+S+S+ SS+    +  + 
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDED 2676

Query: 195  LSTEVEPKESPHP 207
             S   + + +P P
Sbjct: 2677 SSCSSDDEAAPAP 2689



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 33/86 (38%), Positives = 43/86 (50%)

Query: 123  AAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTL 182
            AA   S+   + S  SSSS   +SS S SS S   +SSSS  SS S S   SSS+S+S+ 
Sbjct: 2609 AASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668

Query: 183  SSAKPFMSLVKSLSTEVEPKESPHPA 208
            SS+        S   E  P  +  P+
Sbjct: 2669 SSSTTDEDSSCSSDDEAAPAPTAGPS 2694



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 27/63 (42%), Positives = 36/63 (57%)

Query: 119  SPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSAS 178
            SP  ++   S+   + S  SSSS   +SS S SS S   +SSSS  SS S S   SSS+S
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670

Query: 179  TST 181
            ++T
Sbjct: 2671 STT 2673



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 28/63 (44%), Positives = 35/63 (55%)

Query: 135  SPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS 194
            S  SS +   ASS S SS S   +SSSS  SS S S   SSS+S+S+ SS+    S   S
Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2662

Query: 195  LST 197
             S+
Sbjct: 2663 SSS 2665



 Score = 37.7 bits (86), Expect = 0.062
 Identities = 43/172 (25%), Positives = 63/172 (36%), Gaps = 7/172 (4%)

Query: 40   ASGEEEEEEEEEFREYFEEGLDDQSIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLS 99
            A  E++  EE E       G    S  +     E    E +   D  G           S
Sbjct: 2547 AQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSET---EGEEEGDKNGDGGCGTGGRNCS 2603

Query: 100  VSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTS 159
             + + A  P S ++     S   ++   S+   + S  SSSS   +SS S SS S   +S
Sbjct: 2604 AASSRAASPASSSS----SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2659

Query: 160  SSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHR 211
            SSS  SS S S      +S S+   A P  +   S    +  K +    + R
Sbjct: 2660 SSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKAR 2711



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 16/114 (14%)

Query: 135  SPGSSSSGPLASSPSVSSLSEQK----------------TSSSSPLSSPSKSPILSSSAS 178
            S GSSSS   +SS    +  E++                +++SS  +SP+ S   SSS+S
Sbjct: 2564 SSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSS 2623

Query: 179  TSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDT 232
            +S+ SS+    S   S S+      S   +       +   S S+ +S  + D+
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDS 2677


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 3/129 (2%)

Query: 79   PQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGS 138
            P     P GPA +  L    + S A  + P S  T+ L  +PVP     +   LA++P S
Sbjct: 1753 PLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAS 1812

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTE 198
            + S    +S  V S S    ++  P++  S+ P+      T TL S  P      +    
Sbjct: 1813 TQSPASQASSLVVSAS---GAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGG 1869

Query: 199  VEPKESPHP 207
              P+  P P
Sbjct: 1870 PRPRRQPPP 1878



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 52/222 (23%), Positives = 85/222 (38%), Gaps = 23/222 (10%)

Query: 87   GPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLAS 146
            G    P     LS++ A +++P    T+ L  +P P      T+ LA +P  + + P+  
Sbjct: 1705 GNPQGPFPTQTLSLTPASSLVPTPAQTLSL--APGPPLGPTQTLSLAPAPPLAPASPVGP 1762

Query: 147  SPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESP- 205
            +P+ +      +SS+S L+  S   +  S A   TL  A      +   ST+    ++  
Sbjct: 1763 APAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASS 1822

Query: 206  ---HPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKT 262
                 +    L  T+V  L       ++ T+   PP              P +T   S  
Sbjct: 1823 LVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPP-------------SPPST-ATSFG 1868

Query: 263  APSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQL 304
             P      P   RS F +  +E   E  KR+ SE +   FQL
Sbjct: 1869 GPRPRRQPPPPPRSPFYLDSLE---EKRKRQRSERLERIFQL 1907



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 39/127 (30%), Positives = 57/127 (44%), Gaps = 21/127 (16%)

Query: 98   LSVSQAPAILP-VSKNTVKLLESPVP--AAQVLSTVPLAVS---------PGSSSS---- 141
            L  ++AP   P + +  +KL+ SP P  +A      PL +S         PG +SS    
Sbjct: 1358 LGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPI 1417

Query: 142  ---GPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTE 198
                PLAS   VSS      SSS P+S P+  P  +S+  T  +S+     +   +L T 
Sbjct: 1418 PNSSPLASP--VSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTS 1475

Query: 199  VEPKESP 205
            V P  +P
Sbjct: 1476 VTPPLAP 1482



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 11/102 (10%)

Query: 86   AGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLA 145
            + P A+P+     S    P+ LP   +      SP+P   + ++ PLA    S+ S PL+
Sbjct: 1388 SAPGAAPLTIS--SPLHVPSSLPGPAS------SPMP---IPNSSPLASPVSSTVSVPLS 1436

Query: 146  SSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKP 187
            SS  +S  +     +S+PL+ P  +P+  S++  + L+S  P
Sbjct: 1437 SSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTP 1478



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 54/253 (21%), Positives = 88/253 (34%), Gaps = 35/253 (13%)

Query: 79   PQVGHDPAGPAASPVL-----ADGLSVSQAPA----ILPVSKNTVKLLESPVPAAQVLST 129
            P +    A P+AS +      A  LS SQ P     + P S +   L  +  PA      
Sbjct: 1491 PSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACS---- 1546

Query: 130  VPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFM 189
             P+ V P S+ + P  S+P+ +       + +S  S    +P+   +A  + + +  P  
Sbjct: 1547 -PVLV-PASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAP 1604

Query: 190  SLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQ 249
             L         P  +P  A  +  +  +  S +  TS   +  V    P           
Sbjct: 1605 PLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTP----------- 1653

Query: 250  FTQPRNTGGDSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKII 309
               P +T         SPL SP+ T++    P +   +  +          P Q LS   
Sbjct: 1654 VLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGS---------SPSQTLSLGT 1704

Query: 310  GEESGSHRPKALS 322
            G   G    + LS
Sbjct: 1705 GNPQGPFPTQTLS 1717



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 43/169 (25%), Positives = 66/169 (39%), Gaps = 29/169 (17%)

Query: 132  LAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPIL---------SSSASTSTL 182
            L + P ++S  PL         SE+ T + +P SSP K   L         +SS++TS+ 
Sbjct: 2652 LELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSP 2711

Query: 183  SSAKPFMSLVKSLSTEVE--------PKESPHPARHRHLMKTLV-----KSLSTDTSRQE 229
                P     +  S +VE        P + P P   R L   LV     K L     +Q 
Sbjct: 2712 EGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQR 2771

Query: 230  SDTVSYKPPDSKLNLH----LFKQFTQPRNT---GGDSKTAPSSPLTSP 271
                +  P  S+ +        +  + P ++   GG  + APSS L +P
Sbjct: 2772 GAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTP 2820



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 55/236 (23%), Positives = 89/236 (37%), Gaps = 31/236 (13%)

Query: 88   PAASPVLADGLSVSQAPAILP-------VSKNTVKLLESP-VPAAQVLSTVPLAVSPGSS 139
            P +SP      + +  PA  P       V+ ++  LL  P VP +  ++ +PL + P + 
Sbjct: 2493 PCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAE 2552

Query: 140  SSGPLASSPSVSSLSEQKTSSSSPLS-------SPSKSPILSSSASTSTLSSAKPFMSLV 192
                  +SP    L+   +S +S LS        P    IL  S    +L+ + P ++L 
Sbjct: 2553 LCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLE 2612

Query: 193  KSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKP---PDSKLNLHLFKQ 249
                   + +E+P  A    L   L +         ES+ +   P    D  L   L   
Sbjct: 2613 AGSIPNGQEQEAPDSAEGTTL-TVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEAD 2671

Query: 250  FTQPRNTGGDSKTAPSSP----------LTSPSDTRSFFKVPEMEAKIEDTKRRLS 295
             T    T  ++KT  SSP          + +PS + S    PE  +     +RR S
Sbjct: 2672 RTSEELT--EAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTS 2725



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 40/140 (28%), Positives = 54/140 (38%), Gaps = 32/140 (22%)

Query: 86   AGPAASPV-------LADGLSVS---------QAPAILPVSKNTVKLLESPVPAAQVLST 129
            + P ASPV       L+  L +S          AP  +P+S         P     V  T
Sbjct: 1420 SSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSV--T 1477

Query: 130  VPLA----VSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSA 185
             PLA     +PG  S  P  +SPS S+L+             + +P LSSS +       
Sbjct: 1478 PPLAPVVPAAPGPPSLAPSGASPSASALT----------LGLATAPSLSSSQTPGHPLLL 1527

Query: 186  KPFMSLVKSLSTEVEPKESP 205
             P  S V  L++ V P  SP
Sbjct: 1528 APTSSHVPGLNSTVAPACSP 1547



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 9/115 (7%)

Query: 85   PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
            P+   A   L+  L+ +Q P  +  +   VK++    P   +    PLA +P   SSG  
Sbjct: 1280 PSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSG-- 1337

Query: 145  ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEV 199
               P+V  L+ + T +   L +P+   + ++ A   T +  +P + LV S S EV
Sbjct: 1338 --LPAV--LNPRPTLTPGRLPTPT---LGTARAPMPTPTLVRPLLKLVHSPSPEV 1385



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 34/116 (29%), Positives = 57/116 (49%), Gaps = 14/116 (12%)

Query: 85   PAGPAASPVLADGLS--VSQAPAILP--VSKNTVKLLESPVPAAQVLSTVPLAV---SPG 137
            P  PA  P  + GL   ++  P + P  +   T+    +P+P   ++  +   V   SP 
Sbjct: 1326 PLAPAPRPP-SSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPE 1384

Query: 138  SSSSGPLASSPSVSSLSEQKTS----SSSPLSSPSKSPILSSSASTST--LSSAKP 187
             S+S P A+  ++SS     +S    +SSP+  P+ SP+ S  +ST +  LSS+ P
Sbjct: 1385 VSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLP 1440


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 68/282 (24%), Positives = 106/282 (37%), Gaps = 36/282 (12%)

Query: 9    AEKTTDMPKPSAPKVHVQRSVSR-----DTIAIHFSASGEEEEEEEEEFREYFEEGLDDQ 63
            A  TT  P  S     V+ S +       T  +HF  S       EE    +        
Sbjct: 4533 ATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSST---TH 4589

Query: 64   SIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPA 123
            +I +       L  EP   H   G  A+    D  + S        S ++     + V  
Sbjct: 4590 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 4649

Query: 124  AQVLSTVPLA------VSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSA 177
            A+  ++V L       +S GS  +  L  S +   LSE+ T+  S   SPS +P    SA
Sbjct: 4650 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS---SPSSTPTTHFSA 4706

Query: 178  STSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKP 237
            S++TL  ++   ++    S+ V    +P PAR            ST +   E  T  +  
Sbjct: 4707 SSTTLGRSEESTTV---HSSPVATATTPSPAR------------STTSGLVEESTAYHSS 4751

Query: 238  PDSKLNLHLFKQFTQPRNTGGDSKTAPSS---PLTSPSDTRS 276
            P S   +H F + +       +S+T+ SS    ++SP  T S
Sbjct: 4752 PGSTQTMH-FPESSTASGRSEESRTSHSSTTHTISSPPSTTS 4792



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 51/201 (25%), Positives = 76/201 (37%), Gaps = 20/201 (9%)

Query: 85   PAGPAAS----PVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQ---VLSTVPLAVSPG 137
            P  PA++    P       + +     P S  +     SP  +     V  + P  +SP 
Sbjct: 2444 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPS 2503

Query: 138  SSSSGPLASSPSVSSLSEQKTSSSSPLSSP--SKSPILSSSASTSTLSSAKPFMSLVKSL 195
            S+ +  L  SP+  SLSE+ T+  +   SP  + SP  ++S+  S  SS     S   S 
Sbjct: 2504 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS--HSQPGST 2561

Query: 196  STEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLH---------L 246
             T   P  +  P   RH   +     STDT+   + T +  P       H         L
Sbjct: 2562 HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL 2621

Query: 247  FKQFTQPRNTGGDSKTAPSSP 267
                T   + G +S T  SSP
Sbjct: 2622 SPGSTTALSFGQESTTFHSSP 2642



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 62/273 (22%), Positives = 105/273 (38%), Gaps = 32/273 (11%)

Query: 135  SPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS 194
            SPGS+ +    +S + S  SE+ T   S   SP  S    SSA ++T    +   S +  
Sbjct: 1167 SPGSTPTTHFPASSTTSGHSEKSTIFHS---SPDASGTTPSSAHSTTSGRGESTTSRISP 1223

Query: 195  LSTEVE--PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQ 252
             STE+   P  +  P         L ++ +T  S   S T +  P  S  +L + ++ T 
Sbjct: 1224 GSTEITTLPGSTTTPG--------LSEASTTFYSSPRSPTTTLSPA-SMTSLGVGEESTT 1274

Query: 253  PRNTGGDS-KTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGE 311
             R+  G +  T   +  T+P        + E    +  + R  +E    P    + + GE
Sbjct: 1275 SRSQPGSTHSTVSPASTTTPG-------LSEESTTVYSSSRGSTETTVFPHSTTTSVHGE 1327

Query: 312  ESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSNIPRSDHPK 371
            E  +   +  S+  +  +  S+ +G         + EE     G    + + +P +    
Sbjct: 1328 EPTTFHSRPASTHTTLFTEDSTTSG---------LTEESTAFPGSPASTQTGLPATLTTA 1378

Query: 372  STGEPTREIELKS-SQGSSLKDLGLKTSSLVLE 403
              GE +      S S G+ L      TS LV E
Sbjct: 1379 DLGEESTTFPSSSGSTGTKLSPARSTTSGLVGE 1411



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 63/279 (22%), Positives = 95/279 (34%), Gaps = 23/279 (8%)

Query: 9    AEKTTDMPKPSAPKVHVQRSVSR-----DTIAIHFSASGEEEEEEEEEFREYFEEGLDDQ 63
            A  TT  P  S     V+ S +       T  +HF  S       EE    +        
Sbjct: 1893 ATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSST---TH 1949

Query: 64   SIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPA 123
            +I +       L  EP   H   G  A+    D  + S        S ++     + V  
Sbjct: 1950 TISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 2009

Query: 124  AQVLSTVPLA------VSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSA 177
            A+  ++V L       +S GS  +  L  S +   LSE+ T+  S   SP+ +   +S+ 
Sbjct: 2010 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTT 2069

Query: 178  STSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKP 237
            S+     +    S   S  T   P  +  P   RH   +     STDT+   + T +  P
Sbjct: 2070 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 2129

Query: 238  PDSKLNLH---------LFKQFTQPRNTGGDSKTAPSSP 267
                   H         L    T   + G +S T  SSP
Sbjct: 2130 SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSP 2168



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 54/244 (22%), Positives = 89/244 (36%), Gaps = 45/244 (18%)

Query: 49   EEEFREYFEEGLDDQSIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILP 108
            +E    +   G  D ++  G      L  E    H   G   + +L D  + S       
Sbjct: 1745 QESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG------ 1798

Query: 109  VSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLS--- 165
                   LLE+  P      +    +SP  S++    S+   S  S + T  + P +   
Sbjct: 1799 -------LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSA 1851

Query: 166  ----------SPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMK 215
                      SPS +P    SAS++TL  ++   ++    S+ V    +P PAR      
Sbjct: 1852 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV---HSSPVATATTPSPAR------ 1902

Query: 216  TLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSS---PLTSPS 272
                  ST +   E  T  +  P S   +H F + +       +S+T+ SS    ++SP 
Sbjct: 1903 ------STTSGLVEESTAYHSSPGSTQTMH-FPESSTASGRSEESRTSHSSTTHTISSPP 1955

Query: 273  DTRS 276
             T S
Sbjct: 1956 STTS 1959



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 54/250 (21%), Positives = 91/250 (36%), Gaps = 46/250 (18%)

Query: 49   EEEFREYFEEGLDDQSIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILP 108
            +E    +   G  D ++  G      L  E    H   G   + +L D  + S       
Sbjct: 3302 QESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASG------ 3355

Query: 109  VSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLS--- 165
                   LLE+  P      +    +SP  S++    S+   S  + + T+ + P +   
Sbjct: 3356 -------LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSA 3408

Query: 166  ----------SPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMK 215
                      SPS +P    SAS++TL  ++   ++    S+ V    +P PAR      
Sbjct: 3409 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV---HSSPVATATTPSPAR------ 3459

Query: 216  TLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPL----TSP 271
                  ST +   E  T  +  P S   +H F +       G +S T+ SS      ++P
Sbjct: 3460 ------STTSGLVEESTTYHSSPGSTQTMH-FPESDTTSGRGEESTTSHSSTTHTISSAP 3512

Query: 272  SDTRSFFKVP 281
            S T +  + P
Sbjct: 3513 STTSALVEEP 3522



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 48/219 (21%), Positives = 76/219 (34%), Gaps = 9/219 (4%)

Query: 33   TIAIHFSASGEEEEEEEEEFREYFEEGLDDQSIVTGLEAKEDLYLEPQVGHDPAGPAASP 92
            T  +HF  S       EE    +        +I +       L  EP   H   G  A+ 
Sbjct: 839  TQTMHFPESDTTSGRGEESTTSHSST---THTISSAPSTTSALVEEPTSYHSSPGSTATT 895

Query: 93   VLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLA------VSPGSSSSGPLAS 146
               D  + S        S ++     + V  A+  ++V L       +S GS  +  L  
Sbjct: 896  HFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 955

Query: 147  SPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPH 206
            S +   LSE+ T+  S   SP+ +   +S+ S+     +    S   S  T   P  +  
Sbjct: 956  STTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTT 1015

Query: 207  PARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLH 245
            P   RH   +     STDT+   + T +  P       H
Sbjct: 1016 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 1054



 Score = 37.4 bits (85), Expect = 0.081
 Identities = 54/220 (24%), Positives = 86/220 (39%), Gaps = 26/220 (11%)

Query: 60   LDDQSIVTGL-EAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLE 118
            L D +  +GL EA   ++      H    PA S       +  Q+    P SK+T     
Sbjct: 3347 LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS---WPNSKDT----- 3398

Query: 119  SPVPAAQVLSTVPLAV-SPGSSSSGPL----ASSPSVSSLSEQKTSSSSPLSSPSKSPIL 173
            +P P     + V L+  S GS SS P     ASS ++    E  T  SSP+++ + +P  
Sbjct: 3399 TPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT-ATTPSP 3457

Query: 174  SSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPAR-------HRHLMKTLVKSLSTDTS 226
            + S ++  +  +  + S   S  T   P+      R       H     T+  + ST ++
Sbjct: 3458 ARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSA 3517

Query: 227  RQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSS 266
              E  T  +  P S    H    F     T G S+ + +S
Sbjct: 3518 LVEEPTSYHSSPGSTATTH----FPDSSTTSGRSEESTAS 3553



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 61/273 (22%), Positives = 105/273 (38%), Gaps = 32/273 (11%)

Query: 135  SPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS 194
            SPGS+ +    +S + S  SE+ T   S   SP  S    SSA ++T    +   S +  
Sbjct: 2724 SPGSTPTTHFPASSTTSGHSEKSTIFHS---SPDASGTTPSSAHSTTSGRGESTTSRISP 2780

Query: 195  LSTEVE--PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQ 252
             STE+   P  +  P         L ++ +T  S   S T +  P  S  +L + ++ T 
Sbjct: 2781 GSTEITTLPGSTTTPG--------LSEASTTFYSSPRSPTTTLSPA-SMTSLGVGEESTT 2831

Query: 253  PRNTGGDS-KTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGE 311
             R+  G +  T   +  T+P        + E    +  +    +E    P    + + GE
Sbjct: 2832 SRSQPGSTHSTVSPASTTTPG-------LSEESTTVYSSSPGSTETTVFPRSTTTSVRGE 2884

Query: 312  ESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSNIPRSDHPK 371
            E  +   +  S+  +  +  S+ +G         + EE     G    + + +P +    
Sbjct: 2885 EPTTFHSRPASTHTTLFTEDSTTSG---------LTEESTAFPGSPASTQTGLPATLTTA 2935

Query: 372  STGEPTREIELKS-SQGSSLKDLGLKTSSLVLE 403
              GE +      S S G++L      TS LV E
Sbjct: 2936 DLGEESTTFPSSSGSTGTTLSPARSTTSGLVGE 2968



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 62/279 (22%), Positives = 94/279 (33%), Gaps = 23/279 (8%)

Query: 9    AEKTTDMPKPSAPKVHVQRSVSR-----DTIAIHFSASGEEEEEEEEEFREYFEEGLDDQ 63
            A  TT  P  S     V+ S +       T  +HF  S       EE    +        
Sbjct: 3450 ATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST---TH 3506

Query: 64   SIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPA 123
            +I +       L  EP   H   G  A+    D  + S        S ++     + V  
Sbjct: 3507 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 3566

Query: 124  AQVLSTVPLA------VSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSA 177
            A+  ++V L       +S GS  +  L  S +   LSE+ T+  S   SP+ +   +S+ 
Sbjct: 3567 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTT 3626

Query: 178  STSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKP 237
            S+     +    S   S  T   P  +  P   RH   +     STDT+   + T +   
Sbjct: 3627 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGS 3686

Query: 238  PDSKLNLH---------LFKQFTQPRNTGGDSKTAPSSP 267
                   H         L    T   + G +S T  SSP
Sbjct: 3687 SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSP 3725



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 50/211 (23%), Positives = 79/211 (37%), Gaps = 21/211 (9%)

Query: 6   GRHAEKTTDMPKPSA-------PKVHVQRSVSRDTIAIHFSASGEEEEEEEEEFREYFEE 58
           G  A  TT  P  SA       PK     S S +T A+  S +     E+   F  Y   
Sbjct: 230 GPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTF--YSSP 287

Query: 59  GLDDQSIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSV------SQAPAILPVSKN 112
              D+++         +  +    H   GP  +    D  ++      S A   +P S +
Sbjct: 288 RSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTD 347

Query: 113 TVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPI 172
           T     +  P++    +     SPG + +  L  + + S L E    +S+P+ S + SP 
Sbjct: 348 TTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLE----ASTPVHSSTGSPH 403

Query: 173 LSSSASTSTLSSAKP--FMSLVKSLSTEVEP 201
            + S S+ST    +P  F S   S  T   P
Sbjct: 404 TTLSPSSSTTHEGEPTTFQSWPSSKDTSPAP 434



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 62/278 (22%), Positives = 89/278 (32%), Gaps = 12/278 (4%)

Query: 9   AEKTTDMPKPSAPKVHVQRSVSR-----DTIAIHFSASGEEEEEEEEEFREYFEEGLDDQ 63
           A  TT  P  SA   HV+ S +       T  +HF  S       EE    +        
Sbjct: 482 ATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKS 541

Query: 64  SIVTGLEAKEDLYLEPQVGHDPAGPAASPVLADGLSV-SQAPAILPVSKNTVKLLESPVP 122
           S  +   A         +G              G S  S+A    P +  T  L     P
Sbjct: 542 STPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTP 601

Query: 123 AAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTL 182
           +  V  + P  +S GS  +  L  S +   LSE+ T+  S   SP  + + +S  S+   
Sbjct: 602 SVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVS 661

Query: 183 SSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKL 242
             +    S   S  T   P  +  P   +    +      TDT+     T +        
Sbjct: 662 EESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYT 721

Query: 243 NLHLFKQFTQ----PRNTGGDSKTAPSSPLTSPSDTRS 276
             H     T+    P NT        S P+   S TRS
Sbjct: 722 TFHSRPGSTETTLLPDNTTASGLLEASMPV--HSSTRS 757



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 49/215 (22%), Positives = 82/215 (38%), Gaps = 16/215 (7%)

Query: 60   LDDQSIVTGL-EAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLE 118
            L D +  +GL EA   ++      H    PA S       +  Q+    P SK+T+    
Sbjct: 1790 LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS---WPSSKDTMPAPP 1846

Query: 119  SPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSAS 178
            +   A   LST     SP S+ +   ++S +    SE+ T+  S   + + +P  + S +
Sbjct: 1847 TTTSAFVELSTTSHG-SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 1905

Query: 179  TSTLSSAKPFMSLVKSLSTEVEPKESPHPAR-------HRHLMKTLVKSLSTDTSRQESD 231
            +  +  +  + S   S  T   P+ S    R       H     T+    ST ++  E  
Sbjct: 1906 SGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP 1965

Query: 232  TVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSS 266
            T  +  P S    H    F     T G S+ + +S
Sbjct: 1966 TSYHSSPGSTATTH----FPDSSTTSGRSEESTAS 1996



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 50/218 (22%), Positives = 78/218 (35%), Gaps = 31/218 (14%)

Query: 134  VSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPS--------------KSPILSSSAST 179
            +SPGS+    L  S +   LSE  T+  S   SP+              +    S S   
Sbjct: 3861 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 3920

Query: 180  STLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPD 239
            ST S+  P  +    LS E     S  P           +S +T   R+E  T   +P  
Sbjct: 3921 STHSTVSPASTTTPGLSEESTTVYSSSPGSTE--TTVFPRSTTTSVRREEPTTFHSRPAS 3978

Query: 240  SKLNLHLFKQFTQPRNTGG---DSKTAPSSPLTSPSD---TRSFFKVPEMEAKIEDTKRR 293
            +   L     FT+   T G   +S   P SP ++ +    T +   + E       +   
Sbjct: 3979 THTTL-----FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 4033

Query: 294  LSEVIYEPFQLLSKIIGEESGSHRPKALSSSASELSNL 331
                +       S ++GE +    P  LS S++E + L
Sbjct: 4034 TGTKLSPARSTTSGLVGEST----PSRLSPSSTETTTL 4067



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 62/289 (21%), Positives = 105/289 (36%), Gaps = 19/289 (6%)

Query: 60   LDDQSIVTGLEAKEDLYLE----PQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVK 115
            L   +   GL  K   +      P     PA   +S V  +  +    P  +     T  
Sbjct: 4318 LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSM---HTTAF 4374

Query: 116  LLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSS 175
               + +P     ST   + SPGS+ +     S + SSL  + T+  S   S   + +  +
Sbjct: 4375 PSSTTMPGVSQESTASHS-SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDN 4433

Query: 176  SASTSTLSSAKPFMSLVKSLSTEVEPK-------ESPHPARHRHLMKTLVKSLSTDTSRQ 228
            + ++  L ++ P  S   S  T + P        ES       +   T     +T ++  
Sbjct: 4434 TTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV 4493

Query: 229  ESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPL---TSPSDTRSFFKVPEMEA 285
            E  T S+  P S    H F   +       +S T  SSP+   T+PS  RS       E+
Sbjct: 4494 ELSTTSHGSPSSTPTTH-FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEES 4552

Query: 286  KIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRPKALSSSASELSNLSSL 334
                +    ++ ++ P    +   GEES +       + +S  S  S+L
Sbjct: 4553 TTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSAL 4601



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 42/168 (25%), Positives = 65/168 (38%), Gaps = 32/168 (19%)

Query: 107 LPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGP-----LASSPSVSSLSEQKTSSS 161
           LP +  T  LLE+  P      +    +SP SS++         S PS    S   + ++
Sbjct: 379 LPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTT 438

Query: 162 SPL--------SSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHL 213
           S          SSPS +P    SAS++TL  ++    +    S+ V    +P PAR    
Sbjct: 439 SAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPV---HSSPVATATTPPPAR---- 491

Query: 214 MKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSK 261
                   S  +   E  T  ++ P S   +H    F +   T G S+
Sbjct: 492 --------SATSGHVEESTAYHRSPGSTQTMH----FPESSTTSGHSE 527



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 49/196 (25%), Positives = 76/196 (38%), Gaps = 20/196 (10%)

Query: 85   PAGPAAS----PVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQ---VLSTVPLAVSPG 137
            P  PA++    P       + +     P S  +     SP  +     V  + P  +SP 
Sbjct: 1361 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPS 1420

Query: 138  SSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLST 197
            S+ +  L  SP+  SLSE+ T+     +SP +SP  + S +T+T S         +  ST
Sbjct: 1421 STETTTLPGSPTTPSLSEKSTTF---YTSP-RSPDATLSPATTTSSGVS------EESST 1470

Query: 198  EVEPKESPHPARHRHLMKTLVKSLSTDTSR-QESDTVSYKPPDSKLNLHLFKQFTQPRNT 256
                  S H         T   S    TS   +  T +   P S     L +Q T   ++
Sbjct: 1471 SHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSS 1530

Query: 257  GGDSKTA--PSSPLTS 270
             GD++T   P   +TS
Sbjct: 1531 PGDTETTLLPDDTITS 1546



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 61/273 (22%), Positives = 105/273 (38%), Gaps = 32/273 (11%)

Query: 135  SPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS 194
            SPGS+ +    +S + S  SE+ T   S   SP  S    SSA ++T    +   S +  
Sbjct: 2250 SPGSTPTTHFPASSTTSGHSEKSTIFHS---SPDASGTTPSSAHSTTSGRGESTTSRISP 2306

Query: 195  LSTEVE--PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQ 252
             STE+   P  +  P         L ++ +T  S   S T +  P  S  +L + ++ T 
Sbjct: 2307 GSTEITTLPGSTTTPG--------LSEASTTFYSSPRSPTTTLSPA-SMTSLGVGEESTT 2357

Query: 253  PRNTGGDS-KTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGE 311
             R+  G +  T   +  T+P        + E    +  +    +E    P    + + GE
Sbjct: 2358 SRSQPGSTHSTVSPASTTTPG-------LSEESTTVYSSSPGSTETTVFPRTPTTSVRGE 2410

Query: 312  ESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSNIPRSDHPK 371
            E  +   +  S+  +  +  S+ +G         + EE     G    + + +P +    
Sbjct: 2411 EPTTFHSRPASTHTTLFTEDSTTSG---------LTEESTAFPGSPASTQTGLPATLTTA 2461

Query: 372  STGEPTREIELKS-SQGSSLKDLGLKTSSLVLE 403
              GE +      S S G++L      TS LV E
Sbjct: 2462 DLGEESTTFPSSSGSTGTTLSPARSTTSGLVGE 2494



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 49/196 (25%), Positives = 76/196 (38%), Gaps = 20/196 (10%)

Query: 85   PAGPAAS----PVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQ---VLSTVPLAVSPG 137
            P  PA++    P       + +     P S  +     SP  +     V  + P  +SP 
Sbjct: 4001 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPS 4060

Query: 138  SSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLST 197
            S+ +  L  SP+  SLSE+ T+     +SP +SP  + S +T+T S         +  ST
Sbjct: 4061 STETTTLPGSPTTPSLSEKSTTF---YTSP-RSPDATLSPATTTSSGVS------EESST 4110

Query: 198  EVEPKESPHPARHRHLMKTLVKSLSTDTSR-QESDTVSYKPPDSKLNLHLFKQFTQPRNT 256
                  S H         T   S    TS   +  T +   P S     L +Q T   ++
Sbjct: 4111 SHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSS 4170

Query: 257  GGDSKTA--PSSPLTS 270
             GD++T   P   +TS
Sbjct: 4171 PGDTETTLLPDDTITS 4186



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 45/195 (23%), Positives = 79/195 (40%), Gaps = 18/195 (9%)

Query: 85   PAGPAAS----PVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQ---VLSTVPLAVSPG 137
            P  PA++    P       + +     P S  +     SP  +     V  + P  +SP 
Sbjct: 2918 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPS 2977

Query: 138  SSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLST 197
            S+ +  L  SP+  SLSE+ T+     +SP +SP  + S +T+T S         +S ++
Sbjct: 2978 STETTTLPGSPTTPSLSEKSTTF---YTSP-RSPDATLSPATTTSSGVSE-----ESSTS 3028

Query: 198  EVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTG 257
              +P  +   A       + +    T +   +  T +   P S     L +Q T   ++ 
Sbjct: 3029 HSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSP 3088

Query: 258  GDSKTA--PSSPLTS 270
            GD++T   P   +TS
Sbjct: 3089 GDTETTLLPDDTITS 3103



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 48/210 (22%), Positives = 82/210 (39%), Gaps = 11/210 (5%)

Query: 135  SPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS 194
            SPGS+ +     S + SSL  + T+  S   S   + +  ++ ++  L ++ P  S   S
Sbjct: 3310 SPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGS 3369

Query: 195  LSTEVEPK-------ESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLF 247
              T + P        ES       +   T     +T ++  E  T S+  P S    H F
Sbjct: 3370 PHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTH-F 3428

Query: 248  KQFTQPRNTGGDSKTAPSSPL---TSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQL 304
               +       +S T  SSP+   T+PS  RS       E+    +    ++ ++ P   
Sbjct: 3429 SASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESD 3488

Query: 305  LSKIIGEESGSHRPKALSSSASELSNLSSL 334
             +   GEES +       + +S  S  S+L
Sbjct: 3489 TTSGRGEESTTSHSSTTHTISSAPSTTSAL 3518



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 48/215 (22%), Positives = 82/215 (38%), Gaps = 16/215 (7%)

Query: 60   LDDQSIVTGL-EAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLE 118
            L D +  +GL EA   ++      H    PA S       +  Q+    P SK+T     
Sbjct: 4430 LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS---WPNSKDTTPAPP 4486

Query: 119  SPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSAS 178
            +   A   LST     SP S+ +   ++S +    SE+ T+  S   + + +P  + S +
Sbjct: 4487 TTTSAFVELSTTSHG-SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 4545

Query: 179  TSTLSSAKPFMSLVKSLSTEVEPKESPHPAR-------HRHLMKTLVKSLSTDTSRQESD 231
            +  +  +  + S   S  T   P+ +    R       H     T+  + ST ++  E  
Sbjct: 4546 SGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEP 4605

Query: 232  TVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSS 266
            T  +  P S    H    F     T G S+ + +S
Sbjct: 4606 TSYHSSPGSTATTH----FPDSSTTSGRSEESTAS 4636



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 58/272 (21%), Positives = 101/272 (37%), Gaps = 32/272 (11%)

Query: 86   AGPAASPVL---ADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLS-----TVPLAVSPG 137
            + P+++P     A   ++ ++     V  + V    +P PA    S     +     SPG
Sbjct: 4694 SSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPG 4753

Query: 138  SSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLST 197
            S+ +     S + S  SE+  +S S  +    SP  ++SA     +S   + S   S++T
Sbjct: 4754 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTS---YHSSPGSIAT 4810

Query: 198  EVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTG 257
               P+                   ST + R E  T S+  PD+     L   FT      
Sbjct: 4811 THFPES------------------STTSGRSEESTASHSSPDTNGITPLPAHFTTSGRI- 4851

Query: 258  GDSKTAPSSPLTSPSDTRSFFKVPEMEAK--IEDTKRRLSEVIYEPFQLLSKIIGEESGS 315
             +S T   SP +  +   S    P + AK  I  +  R  +    P  + S  I  E  S
Sbjct: 4852 AESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTS 4911

Query: 316  HRPKALSSSASELSNLSSLNGHLESNNNYSIK 347
               +A S+  +     ++ +G  + +  +  K
Sbjct: 4912 LYSQAESTHTTAFPASTTTSGLSQESTTFHSK 4943



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 25/215 (11%)

Query: 134  VSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPS--------------KSPILSSSAST 179
            +SPGS+    L  S +   LSE  T+  S   SP+              +    S S   
Sbjct: 2778 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 2837

Query: 180  STLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPD 239
            ST S+  P  +    LS E     S  P       +T V   ST TS +  +  ++    
Sbjct: 2838 STHSTVSPASTTTPGLSEESTTVYSSSPGS----TETTVFPRSTTTSVRGEEPTTFHSRP 2893

Query: 240  SKLNLHLFKQFTQPRNTGGDSKTAPSSPLTSPSD---TRSFFKVPEMEAKIEDTKRRLSE 296
            +  +  LF + +       +S   P SP ++ +    T +   + E       +      
Sbjct: 2894 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 2953

Query: 297  VIYEPFQLLSKIIGEESGSHRPKALSSSASELSNL 331
             +       S ++GE +    P  LS S++E + L
Sbjct: 2954 TLSPARSTTSGLVGEST----PSRLSPSSTETTTL 2984



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 45/202 (22%), Positives = 70/202 (34%), Gaps = 27/202 (13%)

Query: 85   PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
            P G  A+PV      VS      P S  T     S     +   +  +  SPG++ +   
Sbjct: 1596 PPGTTAAPV-----EVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGT--- 1647

Query: 145  ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES 204
                   +L   ++++S  +  P+ SPI S S  T+ L  +     L +  +T      S
Sbjct: 1648 -------ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRS 1700

Query: 205  PHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQP----RNTGGDS 260
            P          TL  + +T +   E  T S+  P S          T P     +T   S
Sbjct: 1701 PD--------TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHS 1752

Query: 261  KTAPSSPLTSPSDTRSFFKVPE 282
                +    SP  T +    PE
Sbjct: 1753 SPGSTDTTLSPGSTTASSLGPE 1774



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 47/210 (22%), Positives = 81/210 (38%), Gaps = 11/210 (5%)

Query: 135  SPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS 194
            SPGS+ +     S + SSL  + T+  S   S   + +  ++ ++  L ++ P  S   S
Sbjct: 1753 SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGS 1812

Query: 195  LSTEVEPK-------ESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLF 247
              T + P        ES           T+    +T ++  E  T S+  P S    H F
Sbjct: 1813 PHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTH-F 1871

Query: 248  KQFTQPRNTGGDSKTAPSSPL---TSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQL 304
               +       +S T  SSP+   T+PS  RS       E+    +    ++ ++ P   
Sbjct: 1872 SASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESS 1931

Query: 305  LSKIIGEESGSHRPKALSSSASELSNLSSL 334
             +    EES +       + +S  S  S+L
Sbjct: 1932 TASGRSEESRTSHSSTTHTISSPPSTTSAL 1961



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 45/202 (22%), Positives = 70/202 (34%), Gaps = 27/202 (13%)

Query: 85   PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
            P G  A+PV      VS      P S  T     S     +   +  +  SPG++ +   
Sbjct: 3153 PPGTTAAPV-----EVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGT--- 3204

Query: 145  ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES 204
                   +L   ++++S  +  P+ SPI S S  T+ L  +     L +  +T      S
Sbjct: 3205 -------ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRS 3257

Query: 205  PHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQP----RNTGGDS 260
            P          TL  + +T +   E  T S+  P S          T P     +T   S
Sbjct: 3258 PD--------TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHS 3309

Query: 261  KTAPSSPLTSPSDTRSFFKVPE 282
                +    SP  T +    PE
Sbjct: 3310 SPGSTDTTLSPGSTTASSLGPE 3331



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 14/151 (9%)

Query: 138  SSSSGPLASSPSVS--SLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSL 195
            S  S  + SSP  +  +L   ++++S  +  P+ SPI S S  T+ L  +     L +  
Sbjct: 4272 SEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKS 4331

Query: 196  STEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQP-- 253
            +T      SP          TL  + +T +   E  T S+  P S          T P  
Sbjct: 4332 TTFYSSPRSPD--------TTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGV 4383

Query: 254  --RNTGGDSKTAPSSPLTSPSDTRSFFKVPE 282
               +T   S    +    SP  T +    PE
Sbjct: 4384 SQESTASHSSPGSTDTTLSPGSTTASSLGPE 4414



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 36/138 (26%), Positives = 58/138 (42%), Gaps = 10/138 (7%)

Query: 139 SSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTE 198
           S SGP A+    ++L    +++S  +  P  SPI S+S  T+ L  +     L +  +T 
Sbjct: 227 SHSGPGATG---TTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTF 283

Query: 199 VEPKESP----HPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPR 254
                SP     PAR      + V   ST +  +   T +   PDS     + ++ T   
Sbjct: 284 YSSPRSPDRTLSPAR---TTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASH 340

Query: 255 NTGGDSKTAPSSPLTSPS 272
           +  G + T  S   T+PS
Sbjct: 341 SIPGSTDTTLSPGTTTPS 358



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 39/170 (22%), Positives = 63/170 (37%), Gaps = 13/170 (7%)

Query: 105  AILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPL 164
            A+ P    T  L+  P       +T P  +S GS+ +  L  S + + LSE+ T+  S  
Sbjct: 4288 ALFPTRSATSVLVGEP-------TTSP--ISSGSTETTALPGSTTTAGLSEKSTTFYSSP 4338

Query: 165  SSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTD 224
             SP  +   +S+ S+     +    S   S+ T   P  +  P   +    +     STD
Sbjct: 4339 RSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTD 4398

Query: 225  TSRQESDTVSYKPPDSKLNLHLFKQFTQ----PRNTGGDSKTAPSSPLTS 270
            T+     T +          H     T+    P NT        S+P+ S
Sbjct: 4399 TTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHS 4448



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 60/273 (21%), Positives = 103/273 (37%), Gaps = 32/273 (11%)

Query: 135  SPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS 194
            SPGS+ +    +S + S  SE+ T   S   SP  S    SSA ++T    +   S +  
Sbjct: 3807 SPGSTPTTHFPASSTTSGHSEKSTIFHS---SPDASGTTPSSAHSTTSGRGESTTSRISP 3863

Query: 195  LSTEVE--PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQ 252
             STE+   P  +  P         L ++ +T  S   S T +  P  S  +L + ++ T 
Sbjct: 3864 GSTEITTLPGSTTTPG--------LSEASTTFYSSPRSPTTTLSPA-SMTSLGVGEESTT 3914

Query: 253  PRNTGGDS-KTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGE 311
             R+  G +  T   +  T+P        + E    +  +    +E    P    + +  E
Sbjct: 3915 SRSQPGSTHSTVSPASTTTPG-------LSEESTTVYSSSPGSTETTVFPRSTTTSVRRE 3967

Query: 312  ESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSNIPRSDHPK 371
            E  +   +  S+  +  +  S+ +G         + EE     G    + + +P +    
Sbjct: 3968 EPTTFHSRPASTHTTLFTEDSTTSG---------LTEESTAFPGSPASTQTGLPATLTTA 4018

Query: 372  STGEPTREIELKS-SQGSSLKDLGLKTSSLVLE 403
              GE +      S S G+ L      TS LV E
Sbjct: 4019 DLGEESTTFPSSSGSTGTKLSPARSTTSGLVGE 4051



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 44/211 (20%), Positives = 77/211 (36%), Gaps = 17/211 (8%)

Query: 134  VSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVK 193
            +SPGS+    L  S +   LSE  T+  S   SP+ +   +S  S      +    S   
Sbjct: 1221 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 1280

Query: 194  SLSTEVEPKESPHP----------ARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLN 243
            S  + V P  +  P          +  R   +T V   ST TS    +  ++    +  +
Sbjct: 1281 STHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTH 1340

Query: 244  LHLFKQFTQPRNTGGDSKTAPSSPLTSPSD---TRSFFKVPEMEAKIEDTKRRLSEVIYE 300
              LF + +       +S   P SP ++ +    T +   + E       +       +  
Sbjct: 1341 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSP 1400

Query: 301  PFQLLSKIIGEESGSHRPKALSSSASELSNL 331
                 S ++GE +    P  LS S++E + L
Sbjct: 1401 ARSTTSGLVGEST----PSRLSPSSTETTTL 1427



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 48/218 (22%), Positives = 77/218 (35%), Gaps = 31/218 (14%)

Query: 134  VSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPS--------------KSPILSSSAST 179
            +SPGS+    L  S +   LSE  T+  S   SP+              +    S S   
Sbjct: 2304 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 2363

Query: 180  STLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPD 239
            ST S+  P  +    LS E     S  P           ++ +T    +E  T   +P  
Sbjct: 2364 STHSTVSPASTTTPGLSEESTTVYSSSPGSTE--TTVFPRTPTTSVRGEEPTTFHSRPAS 2421

Query: 240  SKLNLHLFKQFTQPRNTGG---DSKTAPSSPLTSPSD---TRSFFKVPEMEAKIEDTKRR 293
            +   L     FT+   T G   +S   P SP ++ +    T +   + E       +   
Sbjct: 2422 THTTL-----FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 2476

Query: 294  LSEVIYEPFQLLSKIIGEESGSHRPKALSSSASELSNL 331
                +       S ++GE +    P  LS S++E + L
Sbjct: 2477 TGTTLSPARSTTSGLVGEST----PSRLSPSSTETTTL 2510



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 53/243 (21%), Positives = 84/243 (34%), Gaps = 46/243 (18%)

Query: 79  PQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGS 138
           P   H PA   +S V  +  +    P     S +T     S         +     SPG 
Sbjct: 646 PDTTHLPASMTSSGVSEESTTSHSRPG----STHTTAFPGSTTMPGLSQESTASHSSPGP 701

Query: 139 SSSGPLASSPSVSSLSEQKTS------------------------SSSPLSSPSKSP--I 172
           + +     S + SSL  + T+                        +S P+ S ++SP   
Sbjct: 702 TDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTT 761

Query: 173 LSSSASTSTLSSAKPFMSLVKSLSTE----------VEPKESPHPARHRHLMKTLVKSLS 222
           LS + ST+    +  F S   S  T           VEP  + H      +  T + + S
Sbjct: 762 LSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSH-GSPSSIPTTHISARS 820

Query: 223 TDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPL----TSPSDTRSFF 278
           T +   E  T  +  P S   +H F +       G +S T+ SS      ++PS T +  
Sbjct: 821 TTSGLVEESTTYHSSPGSTQTMH-FPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALV 879

Query: 279 KVP 281
           + P
Sbjct: 880 EEP 882



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 72/382 (18%), Positives = 130/382 (34%), Gaps = 52/382 (13%)

Query: 11   KTTDMP-KPSAPKVHVQRSV----SRDTIAIHFSASGEEEEEEEEEFREYFEEGLDDQSI 65
            +TT +P  P+ P +  + +      R   A    A+       EE    + + G    + 
Sbjct: 1423 ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA 1482

Query: 66   VTGLEAKEDLYLEPQVGHD----------PAGPAASPVLADGLSVSQAPA-----ILPVS 110
                    DL  EP   H           P    AS +     +   +P      +LP  
Sbjct: 1483 FPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD 1542

Query: 111  KNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL--ASSPSVSSLSEQKTSSSSP----- 163
              T  L+E+  P      ++   ++P SS+S  L   S+   S  S   T+ S P     
Sbjct: 1543 TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAA 1602

Query: 164  --------LSSPSKSPILSSSASTSTLSSAKPFMSL-------------VKSLSTEVEPK 202
                     S PS +P    SAS++TL  ++   ++              +S ++ +  +
Sbjct: 1603 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1662

Query: 203  ESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKT 262
             +  P        T +   +T     E  T  Y  P S  +  L    T       +S T
Sbjct: 1663 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP-DTTLSPASTTSSGVSEESTT 1721

Query: 263  A---PSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRPK 319
            +   P S  T+     +       E+    +    ++    P    +  +G ES +    
Sbjct: 1722 SHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSS 1781

Query: 320  ALSSSASELSNLSSLNGHLESN 341
              S+  + L + ++ +G LE++
Sbjct: 1782 PGSTETTLLPDNTTASGLLEAS 1803



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 39/170 (22%), Positives = 62/170 (36%), Gaps = 13/170 (7%)

Query: 105  AILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPL 164
            A+ P    T  L+  P       +T P  +S GS+ +  L  S + + LSE+ T+  S  
Sbjct: 1648 ALFPTRSATSVLVGEP-------TTSP--ISSGSTETTALPGSTTTAGLSEKSTTFYSSP 1698

Query: 165  SSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTD 224
             SP  +   +S+ S+     +    S   S  T   P  +  P   +    +     STD
Sbjct: 1699 RSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD 1758

Query: 225  TSRQESDTVSYKPPDSKLNLHLFKQFTQ----PRNTGGDSKTAPSSPLTS 270
            T+     T +          H     T+    P NT        S+P+ S
Sbjct: 1759 TTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHS 1808



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 39/170 (22%), Positives = 62/170 (36%), Gaps = 13/170 (7%)

Query: 105  AILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPL 164
            A+ P    T  L+  P       +T P  +S GS+ +  L  S + + LSE+ T+  S  
Sbjct: 3205 ALFPTRSATSVLVGEP-------TTSP--ISSGSTETTALPGSTTTAGLSEKSTTFYSSP 3255

Query: 165  SSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTD 224
             SP  +   +S+ S+     +    S   S  T   P  +  P   +    +     STD
Sbjct: 3256 RSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD 3315

Query: 225  TSRQESDTVSYKPPDSKLNLHLFKQFTQ----PRNTGGDSKTAPSSPLTS 270
            T+     T +          H     T+    P NT        S+P+ S
Sbjct: 3316 TTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 3365



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 65/295 (22%), Positives = 99/295 (33%), Gaps = 59/295 (20%)

Query: 79   PQVGHDPAGPAASPVLADGLSVSQAPA-----ILPVSKNTVKLLESPVPAAQVLSTVPLA 133
            P     PA   +S V  +  +    P        P S  T  L + P  +     +    
Sbjct: 4090 PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEAT 4149

Query: 134  VSPGSSSSGPLA-------SSPS------------VSSLSEQKTSSSSPLSSPSKSPILS 174
            +SPGS+++  L        SSP              S L E  T + S   S   +   +
Sbjct: 4150 LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPA 4209

Query: 175  SSASTSTLSSAKPFMSLVKSLSTEVEPK---------ESPHPARHRHLMKTLVKSLSTDT 225
            SS ST     +  F S   S  T   P           + + +R      T   + ST  
Sbjct: 4210 SSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTL 4269

Query: 226  SRQESDTVSYKPPD----------SKLNLHLFKQFTQPRNTGGDSKTA-PSSPLTSPSDT 274
             R E  T  +  P           S  ++ + +  T P ++G    TA P S  T+    
Sbjct: 4270 GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE 4329

Query: 275  RS--FFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEES-GSH-RPKALSSSA 325
            +S  F+  P           R  +    P    S  + EES  SH RP ++ ++A
Sbjct: 4330 KSTTFYSSP-----------RSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTA 4373



 Score = 30.4 bits (67), Expect = 10.0
 Identities = 65/302 (21%), Positives = 105/302 (34%), Gaps = 49/302 (16%)

Query: 135  SPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKS 194
            SPGS+ +     S + S + E  T   S   SP  +   +SS S      +  F +   S
Sbjct: 3724 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS 3783

Query: 195  LSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPR 254
              T   P                    ST T+  E  T  ++ P S    H    F    
Sbjct: 3784 THTTPSPP-------------------STATAPVEESTTYHRSPGSTPTTH----FPASS 3820

Query: 255  NTGGDSK------TAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLS----EVIYEPFQL 304
             T G S+      ++P +  T+PS   S         + E T  R+S    E+   P   
Sbjct: 3821 TTSGHSEKSTIFHSSPDASGTTPSSAHS-----TTSGRGESTTSRISPGSTEITTLPGST 3875

Query: 305  LSKIIGEESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSDSNI 364
             +  + E S +      SS  S  + LS       S  +  + EE   S      + S +
Sbjct: 3876 TTPGLSEASTTF----YSSPRSPTTTLSP-----ASMTSLGVGEESTTSRSQPGSTHSTV 3926

Query: 365  -PRSDHPKSTGEPTREIELKSSQGSSLKDLGLKTSSLVLEKCSLSALVSKEDEEFCELYT 423
             P S       E +  +   SS GS+   +  ++++  + +   +   S+       L+T
Sbjct: 3927 SPASTTTPGLSEESTTV-YSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFT 3985

Query: 424  ED 425
            ED
Sbjct: 3986 ED 3987


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 57/253 (22%), Positives = 98/253 (38%), Gaps = 29/253 (11%)

Query: 108 PVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSP 167
           P+   ++    SP P    L T   + SP +SS     +  S+++ + Q T++++ LSSP
Sbjct: 230 PLPTGSIHTTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTSMTTTASQPTATNT-LSSP 288

Query: 168 -----SKSPILSSSASTSTLSSAKPFMSLVKSLSTEVE----PKESPHPARHRHLMKTLV 218
                S +P+LS+   TS +++  P  +LV +L T +       E+ +P      +    
Sbjct: 289 TRTILSSTPVLSTETITSGITNTTPLSTLVTTLPTTISRSTPTSETTYPTSPTSTVTDST 348

Query: 219 KSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQP------RNTGGDSKTAPS------- 265
             ++  TS   + +     P +  +L   +  T P        T   S + PS       
Sbjct: 349 TKIAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISSHSTPSFSSSTIY 408

Query: 266 SPLTSPSDTRSFFKVPEMEAKIEDTKRRLSE------VIYEPFQLLSKIIGEESGSHRPK 319
           S +TS S  R    +   E     T R  S         +      S I   E+ SH   
Sbjct: 409 STVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTETTSHSTP 468

Query: 320 ALSSSASELSNLS 332
           + +SS +     S
Sbjct: 469 SFTSSITTTETTS 481



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 55/242 (22%), Positives = 97/242 (40%), Gaps = 29/242 (11%)

Query: 100 VSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQK-T 158
           +S +P+I     +++    SP  +   ++      +P SS S  +   P   + +    T
Sbjct: 689 ISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLT 748

Query: 159 SSSSPLSSPSKSPIL--SSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKT 216
           S++   +SP+ + +   S+ +STSTL +  P  +L    ST V   + P P+ H   ++T
Sbjct: 749 SATGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTAL----STIVSTSQVPIPSTHSSTLQT 804

Query: 217 L--VKSLSTD-TSRQESDTVSYKPPDSKLN--LHLFKQFTQPRNTGGDSKTAPSSPLTSP 271
                SL T  TS  E  T S+    +  N  L  F              ++PSS   +P
Sbjct: 805 TPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITP 864

Query: 272 SDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIIGEESGSHRPKALSSSASELSNL 331
             + +   VP                   P+   ++ +G  S +  P   SS+ +  S+ 
Sbjct: 865 VFSTTIHSVPS-----------------SPYIFSTENVGSASITGFPSLSSSATTSTSST 907

Query: 332 SS 333
           SS
Sbjct: 908 SS 909



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 46/167 (27%), Positives = 76/167 (45%), Gaps = 19/167 (11%)

Query: 129  TVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKS--PILSSSASTSTLSSAK 186
            T+ ++ SP S+S  P+ S+   S  S     S+  + S S +  P LSSSA+TST S++ 
Sbjct: 850  TIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSS 909

Query: 187  PF---MSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTS-RQESDTVSYKPPDSKL 242
                 ++ +   S    P  +P P     +  T+V +  TD     +  T +  PP + L
Sbjct: 910  SLTTALTEITPFSYISLPSTTPCPGT---ITITIVPASPTDPCVEMDPSTEATSPPTTPL 966

Query: 243  NLHLF--KQFTQPRNTGGDSKTAPSSPLTSPSDTRSFFKVPEMEAKI 287
             +  F  +  T P      +  +  + LT+  DT S   +PE E+ I
Sbjct: 967  TVFPFTTEMVTCP------TSISIQTTLTTYMDTSSM--MPESESSI 1005



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 106  ILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSL--SEQKTSSSSP 163
            I+P S     +   P   A    T PL V P ++      +S S+ +   +   TSS  P
Sbjct: 940  IVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTTYMDTSSMMP 999

Query: 164  LSSPSKSPILSSSASTSTLSSAKPFMS 190
             S  S SP  SSS  T T+ +   F S
Sbjct: 1000 ESESSISPNASSSTGTGTVPTNTVFTS 1026



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 19/64 (29%), Positives = 32/64 (50%), Gaps = 8/64 (12%)

Query: 120  PVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSAST 179
            P+P   V ST+PL + P S       S P++   S + T  S P +  S++P+ ++   T
Sbjct: 1043 PLPLPGV-STIPLTMKPSS-------SLPTILRTSSKSTHPSPPTTRTSETPVATTQTPT 1094

Query: 180  STLS 183
            +  S
Sbjct: 1095 TLTS 1098


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 53/196 (27%), Positives = 79/196 (40%), Gaps = 19/196 (9%)

Query: 88   PAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLST---VPLAVSPGSSSSGPL 144
            P  SP  A     +  P     S +T +    PV +    ST    PL V+  SS+S   
Sbjct: 2978 PVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQ 3037

Query: 145  ASSPSVSSLSEQKTSSSSPL--SSPSK------SPILSSSASTSTLSSAKPF----MSLV 192
            A+   V+SLS   T  ++PL  +SPS       +P+L + AS+++   A P     +S V
Sbjct: 3038 ATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSV 3097

Query: 193  KSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQ 252
             +  T   P  SP  A   H     V    TDTS   +   +  P     + +     + 
Sbjct: 3098 STGDTTPLPVTSPSSASTGHATSLPV----TDTSSASTGDTTSLPVTDTSSAYTGDTTSL 3153

Query: 253  PRNTGGDSKTAPSSPL 268
            P      S T  ++PL
Sbjct: 3154 PVTDTSSSSTGDTTPL 3169



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 63/222 (28%), Positives = 88/222 (39%), Gaps = 31/222 (13%)

Query: 82   GHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLST---VPLAVSPGS 138
            GH    P  S   A        P   P S +T      PV  A  +ST    PL V+  S
Sbjct: 1308 GHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDAS 1367

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPL--SSPSK------SPILSSSASTSTLSSAKPF-M 189
            S+S   A+   V+SLS   T  ++PL  +SPS       +P+L +  S+++   A P  +
Sbjct: 1368 SASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPV 1427

Query: 190  SLVKSLSTEVE---PKESPHPARHRH---LMKTLVKSLSTD--TSRQESDTVSYKPPDSK 241
            +   S+ST+     P   P  A   H   L  T   S ST   TS   +DT S    D+ 
Sbjct: 1428 TDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTT 1487

Query: 242  LNLHLFKQFTQPRNTGGDSKTAPSSPL--TSPSDTRSFFKVP 281
                       P  +   + T   +PL  TSPS   +    P
Sbjct: 1488 ---------PLPVTSTSSASTGHVTPLHVTSPSSASTGHATP 1520



 Score = 37.4 bits (85), Expect = 0.081
 Identities = 33/96 (34%), Positives = 45/96 (46%), Gaps = 10/96 (10%)

Query: 87   GPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLAS 146
            G A S ++ D  SVS          +T  L  +   +A    T PL V+  SS S   A+
Sbjct: 1868 GHATSLLVTDASSVSTG--------DTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHAT 1919

Query: 147  SPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTL 182
            S  V+SLS   T  ++PL  P  SP  +SS  T+ L
Sbjct: 1920 SLPVTSLSSASTGDTTPL--PVTSPSSASSGHTTPL 1953



 Score = 37.4 bits (85), Expect = 0.081
 Identities = 53/193 (27%), Positives = 75/193 (38%), Gaps = 24/193 (12%)

Query: 85   PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLST---VPLAVSPGSSSS 141
            P G A S  + D  SVS   A              PV  A  +ST    PL V+  SS S
Sbjct: 1962 PTGHATSLPVTDASSVSTGHAT-----------PLPVTDASSVSTGHATPLPVTDTSSVS 2010

Query: 142  GPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSL--VKSLSTEV 199
               A+   V+SLS   T  ++PL      P+  +S++++   +  P  SL  V +  T  
Sbjct: 2011 TGQATPLPVTSLSSASTGDTTPL------PVTDTSSASTGQDTPLPVTSLSSVSTGDTTP 2064

Query: 200  EPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGD 259
             P  SP  A   H    LV   S+  S   + ++      S    H         ++   
Sbjct: 2065 LPVTSPSSASTGHATPLLVTDASS-VSTGHATSLLVTDASSVSTGHATALHVTDASSLST 2123

Query: 260  SKTAPSSPLTSPS 272
              T P  P+TSPS
Sbjct: 2124 GDTTP-LPVTSPS 2135



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 51/190 (26%), Positives = 77/190 (40%), Gaps = 16/190 (8%)

Query: 87   GPAASPVLADGLSVSQAPAI-LPV----SKNTVKLLESPVPAAQVLST---VPLAVSPGS 138
            G A S  + D  S S   A  LPV    S +T +    PV +    ST   +PL V+  S
Sbjct: 2172 GHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTS 2231

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTE 198
            S+S   A+   V+SLS   T  ++PL     S + +  A++  ++S    +S V +  T 
Sbjct: 2232 SASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTS----LSSVSTGDTT 2287

Query: 199  VEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGG 258
              P  SP  A   H     V    TD S   +   +  P  S  +         P  +  
Sbjct: 2288 PLPVTSPSSASTGHATPLHV----TDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPS 2343

Query: 259  DSKTAPSSPL 268
             + T  ++PL
Sbjct: 2344 SASTGHATPL 2353



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 44/167 (26%), Positives = 67/167 (40%), Gaps = 21/167 (12%)

Query: 119  SPVPAAQVLS-----TVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPL--SSPSK-- 169
            +P+P   + S     T PL V+  SS S   A+S  V+SLS   T  ++PL  +SPS   
Sbjct: 2239 TPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSAS 2298

Query: 170  ----SPILSSSASTSTLSSAKPF----MSLVKSLSTEVEPKESPHPARHRHLMKTLVKSL 221
                +P+  + AS+++   A P     +S   +  T   P  SP  A   H     V   
Sbjct: 2299 TGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHV--- 2355

Query: 222  STDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPL 268
             TD S   +   +  P  S  +         P      + T  ++PL
Sbjct: 2356 -TDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPL 2401



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 8/119 (6%)

Query: 112  NTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSP 171
            +T  L  +   +A    T PL V+  SS+S   A++  V+S S   T  ++PL      P
Sbjct: 2973 DTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPL------P 3026

Query: 172  ILSSSASTSTLSSAKPFMSL--VKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQ 228
            +  +S++++  ++  P  SL  V +  T   P  SP  A   H    LV   S+ ++ Q
Sbjct: 3027 VTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQ 3085



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 65/222 (29%), Positives = 91/222 (40%), Gaps = 36/222 (16%)

Query: 87   GPAASPVLADGLSVSQAPAI-LPV----SKNTVKLLESPVPAAQVLST---VPLAVSPGS 138
            G A S  + D  SVS      LPV    S +T      PV     +ST    PL V+  S
Sbjct: 1100 GHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDAS 1159

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPL--SSPSK------SPILSSSASTSTLSSAKPF-M 189
            S+S   A+   V+SLS   T  ++PL  +SPS       +P+L +  S+++   A P  +
Sbjct: 1160 SASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPV 1219

Query: 190  SLVKSLSTEVE---PKESPHPARHRH---LMKTLVKSLSTD--TSRQESDTVSYKPPDSK 241
            +   S+ST+     P   P  A   H   L  T   S ST   TS   +DT S    D+ 
Sbjct: 1220 TDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTT 1279

Query: 242  LNLHLFKQFTQPRNTGGDSKTAPSSPL--TSPSDTRSFFKVP 281
                       P  +   + T   +PL  TSPS   +    P
Sbjct: 1280 ---------PLPVTSTSSASTGHVTPLHVTSPSSASTGHATP 1312



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 48/176 (27%), Positives = 69/176 (39%), Gaps = 14/176 (7%)

Query: 99   SVSQAPAILPVSKNTVKLLES---PVPAAQVLST---VPLAVSPGSSSSGPLASSPSVSS 152
            S  QA ++L    ++V   ++   PV +    ST    PL V+  SS+S   A+   V+S
Sbjct: 1466 STGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTS 1525

Query: 153  LSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRH 212
            LS   T  + PL  P  SP  +S+  T+ L       S V +  T   P  SP  A   H
Sbjct: 1526 LSSASTGDTMPL--PVTSPSSASTGDTTPLPVTD--ASSVSTGHTTPLPVTSPSSASTGH 1581

Query: 213  LMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPL 268
                 V    TDTS       +  P  S  +         P      + T  ++PL
Sbjct: 1582 TTPLPV----TDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPL 1633



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 9/99 (9%)

Query: 144 LASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKE 203
           L SSPS S     KT++S     PS SP+L    S    ++     S + S ST   P+E
Sbjct: 578 LLSSPSYSVTQMIKTATS-----PSSSPMLDRHTSQQITTAPSTNHSTIHSTST--SPQE 630

Query: 204 SPHPARHRHLM--KTLVKSLSTDTSRQESDTVSYKPPDS 240
           SP  ++  H    +T  +S +T +    +DT +   P S
Sbjct: 631 SPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGS 669



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 34/113 (30%), Positives = 51/113 (45%), Gaps = 10/113 (8%)

Query: 88   PAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLST---VPLAVSPGSSSSGPL 144
            P  SP  A     +     +P S +T      PV  A   ST    PL V+  SS S   
Sbjct: 3346 PVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGH 3405

Query: 145  ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLST 197
            A+   V+SLS   T  ++PL      P+  +S++++  ++  P  SL  S+ST
Sbjct: 3406 ATPLPVTSLSSVSTGDTTPL------PVTDASSASTGQATPLPVTSL-SSVST 3451



 Score = 34.3 bits (77), Expect = 0.69
 Identities = 44/166 (26%), Positives = 67/166 (40%), Gaps = 20/166 (12%)

Query: 119  SPVPAAQVLS-----TVPLAVS-PGSSSSGPLASSPSVSSLSEQKTSSSSPL-------- 164
            +P+P   + S     T PL V+ P S+SSG   S P V+  S   T   +PL        
Sbjct: 3999 TPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLP-VTDASSVSTGHGTPLPVTSTSSA 4057

Query: 165  SSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTD 224
            S+   +P+  +  S+++   A P    V   S+      +P P      + T   +    
Sbjct: 4058 STGDTTPLPVTDTSSASTGHATPLP--VTDTSSASTGHATPLPVTSLSSVSTGHATPLAV 4115

Query: 225  TSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTS 270
            +S   + TVS    DS L +      T    T G  +TA S P T+
Sbjct: 4116 SSATSASTVS---SDSPLKMETPGMTTPSLKTDGGRRTATSPPPTT 4158



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 59/210 (28%), Positives = 82/210 (39%), Gaps = 28/210 (13%)

Query: 82   GHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVP---AAQVLSTVPLAVSPGS 138
            GH       SP  A     +  P     S +T      PV    +A    T  L V+  S
Sbjct: 1644 GHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVS 1703

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPL--SSPSK------SPILSSSASTSTLSSAKPFMS 190
            S+S   A+   V+SLS   T  ++PL  +SPS       SP+L + AS+++   A P   
Sbjct: 1704 SASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPL-- 1761

Query: 191  LVKSLSTEVEPKESPHPARHRHLMKTLVKSLST-DTSRQESDTVSYKPPDSKLNLHLFKQ 249
                    V    S   A    L  T + S ST DT+R     VS       + L +   
Sbjct: 1762 -------PVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPV--- 1811

Query: 250  FTQPRNTG-GDSKTAPSSPLTSPS--DTRS 276
             T P +   GD+   P +  +S S  DT S
Sbjct: 1812 -TSPSSASTGDTTPLPVTDASSASTGDTTS 1840



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 40/140 (28%), Positives = 61/140 (43%), Gaps = 18/140 (12%)

Query: 87   GPAASPVLADGLSVSQAPAI-LPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLA 145
            G A   ++ D  SVS   A  LPV+  +         +A    T PL V+  SS+S   A
Sbjct: 3628 GHATPLLVTDASSVSTGHATPLPVTDAS---------SASTGDTTPLPVTDTSSASTGQA 3678

Query: 146  SSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKP--FMSLVKSLSTEVEPKE 203
            +   V+SLS   T  ++PL      P+  +S++++  ++  P    S V +  T   P  
Sbjct: 3679 TPLPVTSLSSVSTGDTTPL------PVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVT 3732

Query: 204  SPHPARHRHLMKTLVKSLST 223
            SP  A   H     V  LS+
Sbjct: 3733 SPSSASTGHATPLPVTGLSS 3752



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 43/163 (26%), Positives = 63/163 (38%), Gaps = 16/163 (9%)

Query: 119  SPVPAAQVLS-----TVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPIL 173
            +P+P     S     T PL V+  SS S   A+S  V+S S   T  ++PL     S + 
Sbjct: 3807 TPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVS 3866

Query: 174  SSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLST----DTSRQE 229
            +  A+   ++S     S V +      P  SP  A   H     V S S+    DT+   
Sbjct: 3867 TGHATPLPVTST----SSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLP 3922

Query: 230  SDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTSPS 272
                S         LH+    +  R   GD+ T P +  +S S
Sbjct: 3923 VTNASSLSTGHATPLHVTSPSSASR---GDTSTLPVTDASSAS 3962



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 5/104 (4%)

Query: 82   GHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLST---VPLAVSPGS 138
            GH       SP  A     S  P     S +T      P+ +   +ST    PL V+  S
Sbjct: 3932 GHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTS 3991

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTL 182
            S+S   A+   V+SLS   T  ++PL  P   P  +SS  T++L
Sbjct: 3992 SASTGQATPLPVTSLSSVSTGDTTPL--PVTIPSSASSGHTTSL 4033



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 40/161 (24%), Positives = 61/161 (37%), Gaps = 22/161 (13%)

Query: 135 SPGSSSSGPLASSPS----VSSLSEQKTSSSSPLSSP------SKSPILSSSASTSTLSS 184
           +P + ++G +   PS    +    E  T SS   + P      +++     + +T     
Sbjct: 520 NPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALL 579

Query: 185 AKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSL------STDTSRQESDTVSYKPP 238
           + P  S+ + + T   P  SP   RH     T   S       ST TS QES  VS +  
Sbjct: 580 SSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGH 639

Query: 239 DSKLNLHLFKQFTQPRNTGGDSK--TAPSSPLT----SPSD 273
                     Q T+  +   D+K  T P S  T    SPS+
Sbjct: 640 TQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSE 680



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 50/204 (24%), Positives = 79/204 (38%), Gaps = 38/204 (18%)

Query: 99   SVSQAPAILPVSKNTVKLLES---PVPAAQVLST---VPLAVSPGSSSSGPLASSPSVSS 152
            S  QA ++L    ++V   ++   PV +    ST    PL V+  SS+S   A+   V+S
Sbjct: 1258 STGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTS 1317

Query: 153  LSEQKTSSSSPL--SSPSK----------------------SPILSSSASTSTLSSAKPF 188
            LS   T  + PL  +SPS                       +P+  + AS+++   A P 
Sbjct: 1318 LSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPL 1377

Query: 189  ----MSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNL 244
                +S V +  T   P  SP  A   H    LV    TDTS   +   +  P     ++
Sbjct: 1378 PVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLV----TDTSSASTGHATPLPVTDASSV 1433

Query: 245  HLFKQFTQPRNTGGDSKTAPSSPL 268
                  + P      + T  ++PL
Sbjct: 1434 STDHATSLPVTIPSAASTGHTTPL 1457



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 43/163 (26%), Positives = 62/163 (38%), Gaps = 27/163 (16%)

Query: 82   GHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLST---VPLAV-SPG 137
            GH    P  SP  A     +  P     S +T      PV  A  LST    PL V SP 
Sbjct: 3884 GHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPS 3943

Query: 138  SSSSGPLASSP---------------SVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTL 182
            S+S G  ++ P                ++SLS   T  ++PL      P+  +S++++  
Sbjct: 3944 SASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPL------PVTDTSSASTGQ 3997

Query: 183  SSAKPFMSL--VKSLSTEVEPKESPHPARHRHLMKTLVKSLST 223
            ++  P  SL  V +  T   P   P  A   H     V   S+
Sbjct: 3998 ATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASS 4040



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 34/122 (27%), Positives = 51/122 (41%), Gaps = 19/122 (15%)

Query: 86   AGPAASPVLADGLSVSQAPAI-LPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
            +G   S  + D  SVS      LPV+  +         +A    T PL V+  SS+S   
Sbjct: 4027 SGHTTSLPVTDASSVSTGHGTPLPVTSTS---------SASTGDTTPLPVTDTSSASTGH 4077

Query: 145  ASSPSVSSLSEQKTSSSSPLSSPSKSPI---------LSSSASTSTLSSAKPFMSLVKSL 195
            A+   V+  S   T  ++PL   S S +         +SS+ S ST+SS  P       +
Sbjct: 4078 ATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDSPLKMETPGM 4137

Query: 196  ST 197
            +T
Sbjct: 4138 TT 4139



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 36/154 (23%), Positives = 67/154 (43%), Gaps = 10/154 (6%)

Query: 138 SSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSS---AKPFMSLVKS 194
           S+S    A+          + S  +  S P+ S   ++SA T+T SS   +    S  + 
Sbjct: 761 STSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEG 820

Query: 195 LSTEVE-PKESPHPARHRHLMKTLVKSLSTDTSR---QESDTVSYKPPDSKLNLHLFKQF 250
           +ST  E  + S +P+R  H  ++  + LS   S      S  ++        +  L +  
Sbjct: 821 ISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEAS 880

Query: 251 TQPRNTGGDSKTAPSSPLTSPSDTRSFFKVPEME 284
           T  R TG   +++P+SP  SP +T +  ++ + +
Sbjct: 881 TAGRPTG---QSSPTSPSASPQETAAISRMAQTQ 911



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 50/201 (24%), Positives = 76/201 (37%), Gaps = 22/201 (10%)

Query: 93   VLADGLSVS-----QAPAILPVSKNTVKLLESPV---PAAQVLSTVPLAVSPGSSSSGPL 144
            ++ D  SVS     + P   P S +T      PV   P+A    T PL V+  SS S   
Sbjct: 2482 LVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRH 2541

Query: 145  ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES 204
            A+S  V+S S   T  ++ L      P+  +SA+++  ++  P    V S S+      +
Sbjct: 2542 ATSLHVTSPSSASTGHATSL------PVTDTSAASTGHATPLP----VTSTSSASTGDTT 2591

Query: 205  PHPARHRHLMKT--LVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKT 262
            P P    +   T        TDTS   +   +  P     +         P        T
Sbjct: 2592 PLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVST 2651

Query: 263  APSSPL--TSPSDTRSFFKVP 281
              ++PL  TSPS   +    P
Sbjct: 2652 GHATPLHVTSPSSASTGHTTP 2672



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 50/205 (24%), Positives = 81/205 (39%), Gaps = 34/205 (16%)

Query: 87   GPAASPVLADGLSVSQAPAI-LPVSKNTVKLL--ESPVPAAQVLS-----TVPLAVSPGS 138
            G A S  + D  SVS   A  LPV+  +       +P+P   + S     T PL V+  S
Sbjct: 2732 GHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTS 2791

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTE 198
            S+S   A+   V+SLS   T  ++PL      P+  +S++++  +++ P    V   S+ 
Sbjct: 2792 SASTGQATPLPVTSLSSVSTGDTTPL------PVTDTSSASTGHATSLP----VTDTSSA 2841

Query: 199  VEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGG 258
                 +P P               TDTS   +   +  P     +  +    + P     
Sbjct: 2842 STGHATPLP--------------DTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTS 2887

Query: 259  DSKTAPSSPL--TSPSDTRSFFKVP 281
               T  ++PL  TSPS   +    P
Sbjct: 2888 SISTGHATPLHVTSPSSASTGHATP 2912



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 42/178 (23%), Positives = 67/178 (37%), Gaps = 15/178 (8%)

Query: 119  SPVPAAQVLS-----TVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPIL 173
            +P+P   + S     T PL V+  SS+S   A+   V+SLS   T  ++PL     S + 
Sbjct: 3407 TPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVS 3466

Query: 174  SSSAS------TSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKT--LVKSLSTDT 225
            +  A+      TS+ S+       V   S+    + +P P      + T      L TD 
Sbjct: 3467 TGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDA 3526

Query: 226  SRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPL--TSPSDTRSFFKVP 281
            S   +   +  P     +         P      + T  ++PL  T PS + S    P
Sbjct: 3527 SSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTP 3584



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 48/184 (26%), Positives = 74/184 (40%), Gaps = 20/184 (10%)

Query: 87   GPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLAS 146
            G A S  + D  S+S   A       T   + SP  A+   +T PL V+  SS+S   A+
Sbjct: 2876 GHATSLPVTDTSSISTGHA-------TPLHVTSPSSASTGHAT-PLPVTDTSSASTGHAN 2927

Query: 147  SPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSL--VKSLSTEVEPKES 204
               V+S S   T  ++PL      P+  +S++++  ++  P  SL  V +  T   P  S
Sbjct: 2928 PLHVTSPSSASTGHATPL------PVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTS 2981

Query: 205  PHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAP 264
            P  A   H     V    TDTS   +   +  P  S  +         P      + T  
Sbjct: 2982 PSSASTGHTTPLPV----TDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQ 3037

Query: 265  SSPL 268
            ++PL
Sbjct: 3038 ATPL 3041



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 53/215 (24%), Positives = 82/215 (38%), Gaps = 22/215 (10%)

Query: 87   GPAASPVLADGLSVSQAPAI-LPVSK-------NTVKLLESPVPAAQVLSTVPLAVSPGS 138
            G     ++ D  SVS   A  LPV+        +T +L  +   +A      PL V+  S
Sbjct: 3516 GDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPS 3575

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPL--SSPSK------SPILSSSASTSTLSSAKPFMS 190
            SSS    +   V+S S   T   +PL  +SPS       +P+  +S S+++   A P   
Sbjct: 3576 SSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPL-- 3633

Query: 191  LVKSLSTEVEPKESPHPARHRHLMKT--LVKSLSTDTSRQESDTVSYKPPDSKLNLHLFK 248
            LV   S+      +P P        T        TDTS   +   +  P  S  ++    
Sbjct: 3634 LVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGD 3693

Query: 249  QFTQPRNTGGDSKTAPSSPL--TSPSDTRSFFKVP 281
                P      + T  ++PL  T PS   +   +P
Sbjct: 3694 TTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMP 3728



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 8/106 (7%)

Query: 82   GHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLST---VPLAVSPGS 138
            GH    P  SP        +  P     S++T  +   PV +    ST    PL V+  S
Sbjct: 1004 GHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTS 1063

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSS 184
            S+S    +   V+SLS   T  ++PL         +SSAST   +S
Sbjct: 1064 SASTGHVTPLPVTSLSSASTGDTTPLPVTD-----TSSASTGHATS 1104



 Score = 30.4 bits (67), Expect = 10.0
 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 9/113 (7%)

Query: 82   GHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVP---AAQVLSTVPLAVSPGS 138
            GH    P      A     +  P   P S +T      PV    +A    T PL V+  S
Sbjct: 1580 GHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNAS 1639

Query: 139  SSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSL 191
            S S   A+   V+S S   T  ++PL      P+ S+S++++  ++  P   L
Sbjct: 1640 SLSTGHATPLHVTSPSSASTGHATPL------PVTSTSSASTGHATPLPVTGL 1686


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 30/206 (14%)

Query: 82   GHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSS 141
            GH P+ PA S         S  P    +     +L  +    A   ST   + +PG++  
Sbjct: 4699 GHCPSTPATSSTAMP----SSTPGTTWI---LTELTTTATTTASTGSTATPSSTPGTAPP 4751

Query: 142  GPLASSPSVS--SLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMS--------L 191
              + +SP+ +  + S + TSSSSP ++ +  P+L+S+A+ ST +S  P  S        L
Sbjct: 4752 PKVLTSPATTPTATSSKATSSSSPRTATTL-PVLTSTATKSTATSVTPIPSSTLGTTGTL 4810

Query: 192  VKSLSTEVEPKESPHPA---RHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFK 248
             +  +T V    + HP+      H    L    +T  +   + T S  P  + +   L  
Sbjct: 4811 PEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTEL-- 4868

Query: 249  QFTQPRNTGGDSKTAPSSPLTSPSDT 274
                   T   + TA + P  +PS T
Sbjct: 4869 -------TTAATTTAATGPTATPSST 4887



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 52/213 (24%), Positives = 83/213 (38%), Gaps = 31/213 (14%)

Query: 82   GHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSS 141
            GH P+ PA S         +  P+  P +  T  L E    A    +T   A+   +  +
Sbjct: 3552 GHCPSTPATSS--------TATPSSTPGT--TWILTEQTTAATTTATTGSTAIPSSTPGT 3601

Query: 142  GP----LASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMS------- 190
             P    L S+ +  + +  K +SSS   + +  P+L+S+A+ ST +S  P  S       
Sbjct: 3602 APPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTG 3661

Query: 191  -LVKSLSTEVEPKESPHPA---RHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHL 246
             L +  +T +    + HP+      H    L    +T  +     T S  P  + +   L
Sbjct: 3662 TLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTEL 3721

Query: 247  FKQFTQPRNTGGDSKTAPSSP-----LTSPSDT 274
                T    T G + T  S+P     LT PS T
Sbjct: 3722 TTAATTTAAT-GPTATPSSTPGTTWILTEPSTT 3753



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 49/171 (28%), Positives = 71/171 (41%), Gaps = 17/171 (9%)

Query: 113  TVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSS---PLSSPSK 169
            T  +L  P   A V  TVP   +  +SS+   A +P VS+ +   T +SS   P SSP  
Sbjct: 3099 TTWILTEPSTTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGT 3156

Query: 170  SPILSSSASTSTLSSAKPFMSLVKS--------LSTEVEPKESPHPARHRHLMKTL-VKS 220
            +  L +  ST+T  +A  F ++  S        LS    P  +   A      +T+   +
Sbjct: 3157 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTST 3216

Query: 221  LSTDTSRQESDTVSYKPPDSKL-NLHLFKQFTQPRNTGGDSKTAPSSPLTS 270
            + T T+     T S   P S     H  K  T    T G + T  SSP T+
Sbjct: 3217 VLTTTATTTGATGSVATPSSTPGTAHTTKVLT--TTTTGFTATPSSSPGTA 3265



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 26/176 (14%)

Query: 113  TVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSS---PLSSPSK 169
            T  +L  P   A V  TVP   +  +SS+   A +P VS+ +   T +SS   P SSP  
Sbjct: 4246 TTWILTEPSTTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGT 4303

Query: 170  SPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQE 229
            +  L +  ST+T  +A  F ++               P+       T +   +T T+   
Sbjct: 4304 ATALPALRSTATTPTATSFTAI---------------PSSSLGTTWTRLSQTTTPTATMS 4348

Query: 230  SDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTS-----PSDTRSFFKV 280
            + T S  P  +  +  L    T  R TG  + T  S+P T+     P+ T + F V
Sbjct: 4349 TATPSSTPETAHTSTVLTTTATTTRATGSVA-TPSSTPGTAHTTKVPTTTTTGFTV 4403



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 46/176 (26%), Positives = 71/176 (40%), Gaps = 16/176 (9%)

Query: 113  TVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSS---PLSSPSK 169
            T  +L  P   A V  TVP   +  +SS+   A +P VS+ +   T +SS   P SSP  
Sbjct: 4919 TTWILTEPSTTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGT 4976

Query: 170  SPILSSSASTSTLSSAKPFMSLVKS--------LSTEVEPKESPHPARHRHLMKTL-VKS 220
            +  L +  ST+T  +A  F ++  S        LS    P  +   A      +T+   +
Sbjct: 4977 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTST 5036

Query: 221  LSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTG--GDSKTAPSSPLTSPSDT 274
            + T T+     T S   P S        +      TG      ++P + LT P+ T
Sbjct: 5037 VLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTT 5092



 Score = 30.4 bits (67), Expect = 10.0
 Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 14/150 (9%)

Query: 122  PAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTS- 180
            P  +VL+T     +  SS + P +S  + ++L   ++++++P ++ S +PI SSS  T+ 
Sbjct: 2627 PPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTAT-SVTPIPSSSLGTTW 2685

Query: 181  TLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDS 240
            T  S     +   S +T     E+ H +       T++ + +T T    S       P +
Sbjct: 2686 TRLSQTTTPTATMSTATPSSTPETAHTS-------TVLTATATTTGATGSVATPSSTPGT 2738

Query: 241  KLNLHLFKQFTQPRNTGGDSKTAPSSPLTS 270
                H  K  T    T G + T  SSP T+
Sbjct: 2739 ---AHTTKVPT--TTTTGFTATPSSSPGTA 2763


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 30/206 (14%)

Query: 82   GHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSS 141
            GH P+ PA S         S  P    +     +L  +    A   ST   + +PG++  
Sbjct: 4229 GHCPSTPATSSTAMP----SSTPGTTWI---LTELTTTATTTASTGSTATPSSTPGTAPP 4281

Query: 142  GPLASSPSVS--SLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMS--------L 191
              + +SP+ +  + S + TSSSSP ++ +  P+L+S+A+ ST +S  P  S        L
Sbjct: 4282 PKVLTSPATTPTATSSKATSSSSPRTATTL-PVLTSTATKSTATSVTPIPSSTLGTTGTL 4340

Query: 192  VKSLSTEVEPKESPHPA---RHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFK 248
             +  +T V    + HP+      H    L    +T  +   + T S  P  + +   L  
Sbjct: 4341 PEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTEL-- 4398

Query: 249  QFTQPRNTGGDSKTAPSSPLTSPSDT 274
                   T   + TA + P  +PS T
Sbjct: 4399 -------TTAATTTAATGPTATPSST 4417



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 52/213 (24%), Positives = 83/213 (38%), Gaps = 31/213 (14%)

Query: 82   GHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSS 141
            GH P+ PA S         +  P+  P +  T  L E    A    +T   A+   +  +
Sbjct: 2972 GHCPSTPATSS--------TATPSSTPGT--TWILTEQTTAATTTATTGSTAIPSSTPGT 3021

Query: 142  GP----LASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMS------- 190
             P    L S+ +  + +  K +SSS   + +  P+L+S+A+ ST +S  P  S       
Sbjct: 3022 APPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTG 3081

Query: 191  -LVKSLSTEVEPKESPHPA---RHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHL 246
             L +  +T +    + HP+      H    L    +T  +     T S  P  + +   L
Sbjct: 3082 TLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTEL 3141

Query: 247  FKQFTQPRNTGGDSKTAPSSP-----LTSPSDT 274
                T    T G + T  S+P     LT PS T
Sbjct: 3142 TTAATTTAAT-GPTATPSSTPGTTWILTEPSTT 3173



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 49/171 (28%), Positives = 71/171 (41%), Gaps = 17/171 (9%)

Query: 113  TVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSS---PLSSPSK 169
            T  +L  P   A V  TVP   +  +SS+   A +P VS+ +   T +SS   P SSP  
Sbjct: 2464 TTWILTEPSTTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGT 2521

Query: 170  SPILSSSASTSTLSSAKPFMSLVKS--------LSTEVEPKESPHPARHRHLMKTL-VKS 220
            +  L +  ST+T  +A  F ++  S        LS    P  +   A      +T+   +
Sbjct: 2522 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTST 2581

Query: 221  LSTDTSRQESDTVSYKPPDSKL-NLHLFKQFTQPRNTGGDSKTAPSSPLTS 270
            + T T+     T S   P S     H  K  T    T G + T  SSP T+
Sbjct: 2582 VLTTTATTTGATGSVATPSSTPGTAHTTKVLT--TTTTGFTATPSSSPGTA 2630



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 26/176 (14%)

Query: 113  TVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSS---PLSSPSK 169
            T  +L  P   A V  TVP   +  +SS+   A +P VS+ +   T +SS   P SSP  
Sbjct: 3721 TTWILTEPSTTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGT 3778

Query: 170  SPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQE 229
            +  L +  ST+T  +A  F ++               P+       T +   +T T+   
Sbjct: 3779 ATALPALRSTATTPTATSFTAI---------------PSSSLGTTWTRLSQTTTPTATMS 3823

Query: 230  SDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTS-----PSDTRSFFKV 280
            + T S  P  +  +  L    T  R TG  + T  S+P T+     P+ T + F V
Sbjct: 3824 TATPSSTPETAHTSTVLTTTATTTRATGSVA-TPSSTPGTAHTTKVPTTTTTGFTV 3878



 Score = 37.4 bits (85), Expect = 0.081
 Identities = 54/219 (24%), Positives = 93/219 (42%), Gaps = 31/219 (14%)

Query: 86   AGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPA----AQVLSTVPLAVSPGS--- 138
            A P++SP  A    V  +    P ++ +  +  S +P     A VL+T    V+ GS   
Sbjct: 3321 ATPSSSPGTALTPPVWISTTTTPTTRGST-VTPSSIPGTTHTATVLTTTTTTVATGSMAT 3379

Query: 139  --SSSGPLASSPSVSSLSEQKT---SSSSPLSSPSKSPI---LSSSAST--STLSSAKPF 188
              SS+    + PS+++ +   T   S+++P S+P  +PI   L+++A+T  +T S+  P 
Sbjct: 3380 PSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPS 3439

Query: 189  MSLVKSLSTEVE-----------PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKP 237
             +L  + +  V            P  SPH  R      T    L T    + S   S+ P
Sbjct: 3440 SALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSAT-SGILGTTHITEPSTVTSHTP 3498

Query: 238  -PDSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTSPSDTR 275
               +    H     + P  +   +++ PS   T+P  TR
Sbjct: 3499 AATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTR 3537



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 49/171 (28%), Positives = 71/171 (41%), Gaps = 17/171 (9%)

Query: 113  TVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSS---PLSSPSK 169
            T  +L  P   A V  TVP   +  +SS+   A +P VS+ +   T +SS   P SSP  
Sbjct: 4449 TTWILTEPSTTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGT 4506

Query: 170  SPILSSSASTSTLSSAKPFMSLVKS--------LSTEVEPKESPHPARHRHLMKTL-VKS 220
            +  L +  ST+T  +A  F ++  S        LS    P  +   A      +T+   +
Sbjct: 4507 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTST 4566

Query: 221  LSTDTSRQESDTVSYKPPDSKL-NLHLFKQFTQPRNTGGDSKTAPSSPLTS 270
            + T T+     T S   P S     H  K  T    T G + T  SSP T+
Sbjct: 4567 VLTATATTTGATGSVATPSSTPGTAHTTKVPT--TTTTGFTATPSSSPGTA 4615



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 50/219 (22%), Positives = 91/219 (41%), Gaps = 29/219 (13%)

Query: 86   AGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQ----VLSTVPLAVSPGS--- 138
            A P++SP  A  L V  +    P ++ +  +  S +P       VL+T    V+ GS   
Sbjct: 2621 ATPSSSPGTARTLPVWISTTTTPTTRGST-VTPSSIPGTTHTPTVLTTTTTTVATGSMAT 2679

Query: 139  --SSSGPLASSPSVSSLSEQKT---SSSSPLSSPSKSPI---LSSSAST--STLSSAKPF 188
              SS+    + PS+++ +   T   S+++P S+P  +PI   L+++A+T  +T S+  P 
Sbjct: 2680 PSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPS 2739

Query: 189  MSLVKSLSTEVE-----------PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKP 237
             +L  + +  V               SPH  R      T     +T  +   + T     
Sbjct: 2740 SALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 2799

Query: 238  PDSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTSPSDTRS 276
              +    H     + P  +   +++ PS   T+P  TR+
Sbjct: 2800 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRA 2838



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 50/202 (24%), Positives = 80/202 (39%), Gaps = 27/202 (13%)

Query: 87   GPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPLAS 146
            G  A+P  +     S  P  L  +  T+    S    +    T P+     S+++ P A+
Sbjct: 4665 GSMATP--SSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAAT 4722

Query: 147  SPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPH 206
            S        + TSSSSP ++ +  P+L+S+A+ ST +S  P  S     +T   P ++  
Sbjct: 4723 S-------SKATSSSSPRTATTL-PVLTSTATKSTATSFTPIPSST-LWTTWTVPAQTTT 4773

Query: 207  PARHRHLMKTL-------VKSLSTDTSRQESDTVSYKPPDSKL-NLHLFKQFTQPRNT-- 256
            P      + T          ++ T T+     T S   P S L    +  + T    T  
Sbjct: 4774 PMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTA 4833

Query: 257  -GGDSKTAPSSP-----LTSPS 272
              G + T  S+P     LT PS
Sbjct: 4834 ATGSTATLSSTPGTTWILTEPS 4855



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 49/217 (22%), Positives = 90/217 (41%), Gaps = 29/217 (13%)

Query: 86   AGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPA----AQVLSTVPLAVSPGS--- 138
            A P++SP  A    V  +    P ++ +  +  S +P     A VL+T    V+ GS   
Sbjct: 2064 ATPSSSPGTALTPPVWISTTTTPTTRGST-VTPSSIPGTTHTATVLTTTTTTVATGSMAT 2122

Query: 139  --SSSGPLASSPSVSSLSEQKT---SSSSPLSSPSKSPI---LSSSAST--STLSSAKPF 188
              SS+    + PS+++ +   T   S+++P S+P  +PI   L+++A+T  +T ++  P 
Sbjct: 2123 PSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPS 2182

Query: 189  MSLVKSLSTEVE-----------PKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKP 237
             +L  + +  V            P  SPH  R      T     +T  +   + T     
Sbjct: 2183 SALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLA 2242

Query: 238  PDSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTSPSDT 274
              +    H     + P  +   +++ PS   T+P  T
Sbjct: 2243 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHT 2279



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 46/234 (19%), Positives = 92/234 (39%), Gaps = 36/234 (15%)

Query: 79   PQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTV------------KLLESPVPAAQV 126
            P V    A P++SP  A  L   ++ A  P + +              +L ++  P A +
Sbjct: 4491 PTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATM 4550

Query: 127  -------------LSTVPLAVSPGSSSSGPLA---SSPSVSSLSEQKTSSSSPLSS-PSK 169
                          STV  A +  + ++G +A   S+P  +  ++  T++++  ++ PS 
Sbjct: 4551 STATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 4610

Query: 170  SPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDT--SR 227
            SP  + +      ++  P  +   +  + V P   P       ++ T   +++T +  + 
Sbjct: 4611 SPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATP 4670

Query: 228  QESDTVSYKPPD---SKLNLHLFKQFTQPRNTGGDSKTAP--SSPLTSPSDTRS 276
              S   S  PP    +   +      T P +T G +   P  +S  T+P+ T S
Sbjct: 4671 SSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSS 4724



 Score = 30.4 bits (67), Expect = 10.0
 Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 14/150 (9%)

Query: 122  PAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTS- 180
            P  +VL+T     +  SS + P +S  + ++L   ++++++P ++ S +PI SSS  T+ 
Sbjct: 1937 PPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTAT-SVTPIPSSSLGTTW 1995

Query: 181  TLSSAKPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDS 240
            T  S     +   S +T     E+ H +       T++ + +T T    S       P +
Sbjct: 1996 TRLSQTTTPTATMSTATPSSTPETAHTS-------TVLTATATTTGATGSVATPSSTPGT 2048

Query: 241  KLNLHLFKQFTQPRNTGGDSKTAPSSPLTS 270
                H  K  T    T G + T  SSP T+
Sbjct: 2049 ---AHTTKVPT--TTTTGFTATPSSSPGTA 2073


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 97/480 (20%), Positives = 175/480 (36%), Gaps = 64/480 (13%)

Query: 39   SASGEEEEEEEEEFREYFEEG------LDDQSIVTGLEAK-----EDLYLEPQ-VGHDPA 86
            S+S +  ++ ++  +E F+E       L+   + TG E        D  L P+ +G  P 
Sbjct: 2420 SSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPC 2479

Query: 87   GPAASPVLAD-GLSVSQAPAILPVS-KNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
               +S  + D GLS+   P   P+  + + K L++P      ++  PL +   S S   L
Sbjct: 2480 NNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNAL 2539

Query: 145  ASSPSVSSLSEQKTSSSSPLS---SPSKSPILSSSASTSTLSSAK-------PFMSLVKS 194
              S   S L  + TS + P+S   +P   P+   S + ++   ++       P       
Sbjct: 2540 KESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLM 2599

Query: 195  LSTEVEPKES--------PHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHL 246
            L    +P+E            AR R  M   +  L    S  E D   Y     K     
Sbjct: 2600 LPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKR--- 2656

Query: 247  FKQFTQPRNTGGDSKTAPSSPLTSPSDTRSFFKVPEMEAKIEDTKRRLSEVIYE-----P 301
             K+  + +  G D  +      TS  D   ++            +R  S  ++       
Sbjct: 2657 GKRSAEGQVDGADDLS------TSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCD 2710

Query: 302  FQLLSKIIGEESGSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDGYGSD 361
               +S++ G + G+    +++++  + S +   NG      N  I   E   E +     
Sbjct: 2711 LPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKS 2770

Query: 362  S----NIPRSDH------PKSTGEPTREIELKSSQGSSLKDLGLKTSSLVLEKCSLSALV 411
            S    N P+ D+       K+ G+ + E +L S + S        +   +L+  +   L 
Sbjct: 2771 SVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLK 2830

Query: 412  SKEDEEFCE-----LYTEDFDLETEGESKVDKLSDIP--LKPEVL-AEDGVVLDSEDEVD 463
            S  D    +     L ++  D   +    +  L + P     E+L   +G+ LDS  E D
Sbjct: 2831 SDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKD 2890



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 41/139 (29%), Positives = 55/139 (39%), Gaps = 28/139 (20%)

Query: 118 ESPVPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSA 177
           + P+  A++ ST      P S  S P   S   SS + Q +S  S  SS S SP    S 
Sbjct: 435 DPPIKIARLEST------PNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSP----SV 484

Query: 178 STSTLSSAKPFMSLV---KSLSTEVEP----KESP-----------HPARHRHLMKTLVK 219
            TST S A   + ++   +S + EV P     +SP           +    R       K
Sbjct: 485 DTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTK 544

Query: 220 SLSTDTSRQESDTVSYKPP 238
            LST  S  +  T S  PP
Sbjct: 545 KLSTLQSAPQQQTSSSPPP 563



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 66/295 (22%), Positives = 107/295 (36%), Gaps = 34/295 (11%)

Query: 15  MPKPSAPKVHVQRSVSRDTIAIHFSASGEEEEEEEEEFREYFEEGLDDQSIVTGLE---- 70
           +P  +AP    ++S+ R+      S      E +     +Y +EGL  + I         
Sbjct: 597 LPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPL 656

Query: 71  AKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTV 130
             ED+      G   +G AAS  L   L    +     + K +  L       ++  S +
Sbjct: 657 TPEDVGFAS--GFSASGTAASARLFSPL---HSGTRFDMHKRSPLLRAPRFTPSEAHSRI 711

Query: 131 PLAVSPGSSSSGPLASSPSVSSLSEQKTSSSSPLSSPSKSP-----ILSSSASTSTLSSA 185
             +V+  S+ +    SS  VS+  ++K    SP+ S  +SP       S   S+S LS  
Sbjct: 712 FESVTLPSNRTSAGTSSSGVSN-RKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPL 770

Query: 186 KPFMSLVKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLH 245
            P  S+  SLS  V P               L  S    T    S +++     ++ N  
Sbjct: 771 TPPSSVSSSLSISVSP---------------LATSALNPTFTFPSHSLTQSGESAEKNQR 815

Query: 246 LFKQFTQPRNTGGDSKTAPSSPLTSPSDT----RSFFKVPEMEAKIEDTKRRLSE 296
             KQ + P      S   P  P  +P       R+  K PE  +K  D  + + +
Sbjct: 816 PRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEK 870


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 51/191 (26%), Positives = 71/191 (37%), Gaps = 12/191 (6%)

Query: 83   HDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSG 142
            + P  PA  P    G +  Q+P+  P S +      S  P +   S    + SP S S  
Sbjct: 1593 YSPTSPAYEPRSPGGYT-PQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYS 1651

Query: 143  PLASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTS-TLSSAKPFMSLVKSLSTEVEP 201
            P + S S +S S   TS S   +SPS SP   S + TS + S   P  S      +   P
Sbjct: 1652 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1711

Query: 202  KESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSK 261
              SP    +         S S  +      + SY P     +       T P  T     
Sbjct: 1712 SYSPTSPSY----SPTSPSYSPTSPSYSPTSPSYSPTSPNYSP------TSPNYTPTSPS 1761

Query: 262  TAPSSPLTSPS 272
             +P+SP  SP+
Sbjct: 1762 YSPTSPSYSPT 1772



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 53/204 (25%), Positives = 72/204 (35%), Gaps = 40/204 (19%)

Query: 76   YLEPQVGHDPAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVS 135
            Y      + P  P+ SP          +P   P S N         P +   S    + S
Sbjct: 1755 YTPTSPSYSPTSPSYSPT---------SPNYTPTSPNY-------SPTSPSYSPTSPSYS 1798

Query: 136  PGSSSSGPLASSPSVSSLSEQKTSSS---SPLSSPSKSPILSSSASTS-TLSSAKPFMSL 191
            P S S  P  SSP  +  S   T SS   SP SSPS SP       TS + S + P  + 
Sbjct: 1799 PTSPSYSP--SSPRYTPQSPTYTPSSPSYSP-SSPSYSPTSPKYTPTSPSYSPSSPEYTP 1855

Query: 192  VKSLSTEVEPKESPHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFT 251
                 +   PK SP   ++     T     S  T +    + +Y P             T
Sbjct: 1856 TSPKYSPTSPKYSPTSPKYSPTSPT----YSPTTPKYSPTSPTYSP-------------T 1898

Query: 252  QPRNTGGDSKTAPSSPLTSPSDTR 275
             P  T    K +P+SP  SP+  +
Sbjct: 1899 SPVYTPTSPKYSPTSPTYSPTSPK 1922


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 55/215 (25%), Positives = 80/215 (37%), Gaps = 31/215 (14%)

Query: 43   EEEEEEEEEFREYF---------EEGLDDQSIVTGLEAKEDLYLEPQVGHDPAGPAASPV 93
            EEEEEEEEEF E F         EE  +D+     LE  EDL      G    G    P 
Sbjct: 922  EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPT 981

Query: 94   LADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTV--PLAVSPGSSSSGPLASSPSVS 151
            L         P  LP  ++  K+   P P   +L  V  P       + + P  +  ++ 
Sbjct: 982  L---------PPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032

Query: 152  SLSEQKTSSSSPLSSPSKSPILSSSAST-STLSSAKPFMSLVKSLSTEVEPKESPHPARH 210
            S  E +    SP + P    ++    S   TL   +      +  S +V+P     PA  
Sbjct: 1033 SQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEE-----TEDGSDKVQPPPET-PAEE 1086

Query: 211  RHLMKTLVKSL----STDTSRQESDTVSYKPPDSK 241
                +T  ++L      DT+   +D +   P D K
Sbjct: 1087 EMETETEAEALQEKEQDDTAAMLADFIDCPPDDEK 1121



 Score = 34.3 bits (77), Expect = 0.69
 Identities = 18/53 (33%), Positives = 30/53 (56%)

Query: 28  SVSRDTIAIHFSASGEEEEEEEEEFREYFEEGLDDQSIVTGLEAKEDLYLEPQ 80
           ++  D   I+ ++S EEEEEEEEE  E  EE  +++      E +E+ + E +
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE 925


>gi|120953251 neuron navigator 3 [Homo sapiens]
          Length = 2363

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 68/295 (23%), Positives = 112/295 (37%), Gaps = 41/295 (13%)

Query: 85   PAGPAASPVLADGLSVSQAPAILPVSKNTVKLLESPVPAAQVLSTVPLAVSPGSSSSGPL 144
            P+    S   A GLS S +P     S  T  ++      +  L++ P +V   S +SG L
Sbjct: 1291 PSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVIS----LSHSLASSPASVH--SFTSGGL 1344

Query: 145  ASSPSVSSLSEQKTSSSSPLSSPSKSPILSSSASTSTLSSAKPFMSLVKSLSTEVEPKES 204
              + ++SS      SS+    +PS   + S   S+ ++         +  L+T     +S
Sbjct: 1345 VWAANMSS------SSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQS 1398

Query: 205  PHPARHRHLMKTLVKSLSTDTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAP 264
                R   +  TL +S+  D +      + Y P   + N    K++ +  +TGG   T  
Sbjct: 1399 LL-MRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGN 1457

Query: 265  SSPLTSPSDTRSF--------------------FKVPEMEAKIEDTKRRLSEVIYEPFQL 304
             SPL SPS   S                        P M        +  S  +Y+  QL
Sbjct: 1458 QSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQL 1517

Query: 305  LSKIIGEESGSHRPKALSSSASELSNLSSLNGH-----LESNNNYSIKEEECDSE 354
                   E    RP+A+S S S   ++  ++G        +++ YS  EE+  SE
Sbjct: 1518 CGSATSLE---ERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSE 1569


>gi|110349786 Alstrom syndrome 1 [Homo sapiens]
          Length = 4169

 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 62/225 (27%), Positives = 96/225 (42%), Gaps = 33/225 (14%)

Query: 64   SIVTG-LEAKEDLYLEPQVGHDPAGPAASPVLADGLSVSQAPAIL--PVSKNTVKLLESP 120
            SIV+G  E K D+         PAGP  S  L +        A+L  P++K  VK+  +P
Sbjct: 1599 SIVSGPTEKKTDI---------PAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAP 1649

Query: 121  VPAAQVLSTVPLAVSPGSSSSGPLASSPSVSSLSE--QKTSSSSPLSSPSKSPILSSSAS 178
             PA Q   T+P+  +  S+   P+       S S   ++     P+  P      + S S
Sbjct: 1650 GPADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPGPDAQKTETPSVS 1709

Query: 179  TSTLS-SAKPFMSLVKSLSTEVEPKES------PHPARHRHLMKTLVKSLSTDTSRQESD 231
            +S  S   KP +   ++L      +E+      P PA  +  + T+  S  + T   E  
Sbjct: 1710 SSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHT---EKP 1766

Query: 232  TVSYKP--PDSKLNLHLFKQFTQPRNTGG--DSKTAPSSPLTSPS 272
             +SY+   PDS    HL ++  +  N  G  D KT  S+ +TS S
Sbjct: 1767 NISYQQELPDS----HLTEEALKVSNVPGPADQKTGVST-VTSTS 1806


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,688,424
Number of Sequences: 37866
Number of extensions: 2498845
Number of successful extensions: 18860
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 626
Number of HSP's that attempted gapping in prelim test: 14688
Number of HSP's gapped (non-prelim): 3484
length of query: 1134
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1021
effective length of database: 13,968,660
effective search space: 14262001860
effective search space used: 14262001860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press