Guide to the Human Genome
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Search of human proteins with 38569505

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
         (599 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi...  1178   0.0  
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi...   963   0.0  
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   217   2e-56
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   217   2e-56
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   213   5e-55
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   208   1e-53
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   207   2e-53
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   207   2e-53
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   206   5e-53
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   206   5e-53
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   206   6e-53
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   205   1e-52
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  201   2e-51
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   195   9e-50
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   185   9e-47
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            183   4e-46
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            183   4e-46
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         182   6e-46
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          182   6e-46
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   181   1e-45
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   179   5e-45
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   177   2e-44
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   175   9e-44
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    172   8e-43
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi...   172   1e-42
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   163   4e-40
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   163   4e-40
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi...   159   5e-39
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   157   3e-38
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi...   156   4e-38

>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
           sapiens]
          Length = 599

 Score = 1178 bits (3048), Expect = 0.0
 Identities = 599/599 (100%), Positives = 599/599 (100%)

Query: 1   MDVHDLFRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLDFFGNKKSVPGVCG 60
           MDVHDLFRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLDFFGNKKSVPGVCG
Sbjct: 1   MDVHDLFRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLDFFGNKKSVPGVCG 60

Query: 61  ASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKK 120
           ASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKK
Sbjct: 61  ASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKK 120

Query: 121 VQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNI 180
           VQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNI
Sbjct: 121 VQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNI 180

Query: 181 LDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALII 240
           LDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALII
Sbjct: 181 LDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALII 240

Query: 241 SPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLL 300
           SPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLL
Sbjct: 241 SPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLL 300

Query: 301 KQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDV 360
           KQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDV
Sbjct: 301 KQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDV 360

Query: 361 EQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQ 420
           EQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQ
Sbjct: 361 EQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQ 420

Query: 421 SIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKG 480
           SIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKG
Sbjct: 421 SIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKG 480

Query: 481 VNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE 540
           VNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE
Sbjct: 481 VNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE 540

Query: 541 YIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQNSKKKVALEDKS 599
           YIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQNSKKKVALEDKS
Sbjct: 541 YIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQNSKKKVALEDKS 599


>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
           sapiens]
          Length = 491

 Score =  963 bits (2490), Expect = 0.0
 Identities = 491/491 (100%), Positives = 491/491 (100%)

Query: 109 MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ 168
           MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ
Sbjct: 1   MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ 60

Query: 169 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 228
           EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK
Sbjct: 61  EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 120

Query: 229 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
           QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI
Sbjct: 121 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 180

Query: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348
           LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR
Sbjct: 181 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 240

Query: 349 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 408
           RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK
Sbjct: 241 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 300

Query: 409 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 468
           KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC
Sbjct: 301 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 360

Query: 469 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 528
           TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA
Sbjct: 361 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 420

Query: 529 NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN 588
           NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN
Sbjct: 421 NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN 480

Query: 589 SKKKVALEDKS 599
           SKKKVALEDKS
Sbjct: 481 SKKKVALEDKS 491


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  217 bits (553), Expect = 2e-56
 Identities = 158/527 (29%), Positives = 268/527 (50%), Gaps = 26/527 (4%)

Query: 50  GNKK----SVPGVCGASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGAT 105
           GN+K    +V  V     T +   + +KK+  L E  ++  +   +    ++ +   G  
Sbjct: 252 GNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQ 311

Query: 106 IQWMSSVE----AKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHK-IHVQGTDLPDPI 160
            +    +E     KIE +  ++   +   +L  + +E++N  R + + I V+G   P PI
Sbjct: 312 TKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPI 371

Query: 161 ATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFS 220
            ++ Q      I+ ++L ++   G++ PTPIQ QAIP ++ GR+L+  A TGSGKT+AF 
Sbjct: 372 KSWVQCG----ISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFL 427

Query: 221 IP----ILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAK 276
           +P    I+ Q      +G  A+I++PTRELA QI +E  K S+  G R+  ++     ++
Sbjct: 428 LPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISE 487

Query: 277 KFGPKSSKKFDILVTTPNRLIYLLKQDPPGI-DLASVEWLVVDESDKLFEDGKTGFRDQL 335
           +   +  +  +I+V TP R+I +L  +   + +L  V ++V+DE+D++F+    GF  Q+
Sbjct: 488 QIA-ELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFD---MGFEPQV 543

Query: 336 ASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGS 395
             I       + +  MFSATF   +E   +  L   I V +G R+     VEQ+++ +  
Sbjct: 544 MRIVDNVRPDR-QTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEE 602

Query: 396 ETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTV 455
           E   L  +  L     +  V++FV   E A  L  +L+        +H    Q  RD+ +
Sbjct: 603 EKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSII 662

Query: 456 HSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITF 515
           + F+ G   +L+ T++ ARG+D K + LV+NY  P    +Y+HR GRTGRAGNKG A TF
Sbjct: 663 NDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTF 722

Query: 516 FTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLLSKQKK---KMIKK 559
            TED       +   ++ +G  VP  ++        Q+K   K+IKK
Sbjct: 723 ITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKK 769


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  217 bits (553), Expect = 2e-56
 Identities = 157/473 (33%), Positives = 245/473 (51%), Gaps = 40/473 (8%)

Query: 134 NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQM 193
           NL++++I  L+ +  I VQG ++  PI  F+       +N     N+  +G+++PTPIQM
Sbjct: 176 NLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN----HNLKKSGYEVPTPIQM 231

Query: 194 QAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRE 253
           Q IPV L GR++LASA TGSGKT AF +P++M+    + K   ALI++PTRELA QI R+
Sbjct: 232 QMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFES-KTPSALILTPTRELAIQIERQ 290

Query: 254 LIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVE 313
             ++  G      ++    +       +  +   +++ TP RL+ ++KQ    ++L  V+
Sbjct: 291 AKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS--SVELCGVK 348

Query: 314 WLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVIS 373
            +VVDE+D +    K GF+ Q+  I L    +  +  + SAT    +EQ     L N + 
Sbjct: 349 IVVVDEADTML---KMGFQQQVLDI-LENIPNDCQTILVSATIPTSIEQLASQLLHNPVR 404

Query: 374 VSIGARNSAVETVEQELLFVGSETGKLLAMRELV--KKGFNPPVLVFVQSIERAKELFHE 431
           +  G +N     V Q +L+V  +  K   + E++  KK F PPVLVFV   +   +L  E
Sbjct: 405 IITGEKNLPCANVRQIILWV-EDPAKKKKLFEILNDKKLFKPPVLVFVDC-KLGADLLSE 462

Query: 432 LIYE--GINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF 489
            + +  G+    IH+E++Q +R N +     G   V++ T +L RG+D   V LV+N+D 
Sbjct: 463 AVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDM 522

Query: 490 PTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLL 549
           P+S  EY+H+IGR GR G  G AITF   + K L   +A  ++  G  +P  +      L
Sbjct: 523 PSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLN-SPYL 581

Query: 550 SKQKKKMIKKPLERESISTTPKCFLEKAKDKQKK---VTGQNSKKKVALEDKS 599
             QK+K                   E+ KDKQ +   VTG N    +   DKS
Sbjct: 582 HDQKRK-------------------EQQKDKQTQNDLVTGANLMDIIRKHDKS 615


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  213 bits (541), Expect = 5e-55
 Identities = 154/477 (32%), Positives = 252/477 (52%), Gaps = 27/477 (5%)

Query: 100 QEEGATIQWMSSVEAKIED--KKVQRESKLTSG----KLENLRKEKINFLRNKHKIHVQG 153
           +EEG  ++W  +  A +    K   +ES  TS     + ++ RKE  N   +  K   + 
Sbjct: 177 REEG--LKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLK-DGEK 233

Query: 154 TDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGS 213
             +P+P  TF   D  ++    +++NI  AGFQ PTPIQ QA P++L G +L+  A TG+
Sbjct: 234 RPIPNPTCTF---DDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGT 290

Query: 214 GKTLAFSIPILMQLK-QPANKGFR----ALIISPTRELASQIHRELIKISEGTGFRIHMI 268
           GKTL + +P  + L  QP+ KG R     L+++PTRELA Q+  E  K S   G R   +
Sbjct: 291 GKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSY-KGLRSVCV 349

Query: 269 HKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGK 328
           +      ++   +  K  DI++ TP RL  L  Q    ++L ++ +LV+DE+DK+ +   
Sbjct: 350 YGGGNRDEQI-EELKKGVDIIIATPGRLNDL--QMSNFVNLKNITYLVLDEADKMLD--- 403

Query: 329 TGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNS-AVETVE 387
            GF  Q+  I L     + +  M SAT+ + V +  +  L   + V +G  +  AV +V+
Sbjct: 404 MGFEPQIMKILLDVRPDR-QTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVK 462

Query: 388 QELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERT 447
           Q ++    E         L        V+VFV     A  L  +LI   I+V+ +H +R 
Sbjct: 463 QNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDRE 522

Query: 448 QQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAG 507
           Q+ R+  + +F+ GK+ +LI T L +RG+D   V  V N+DFP +  EY+HRIGRTGRAG
Sbjct: 523 QRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAG 582

Query: 508 NKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGF-QKLLSKQKKKMIKKPLER 563
             G +IT  T +D  +   + N++++A   +PE +    ++  + Q+K+ +++ +ER
Sbjct: 583 RTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAERFKAHQQKREMERKMER 639


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  208 bits (529), Expect = 1e-53
 Identities = 152/504 (30%), Positives = 257/504 (50%), Gaps = 64/504 (12%)

Query: 78  LTERKREQSK------KKRKTMTSEIASQEEGATIQWMSSVEAKIEDKKVQR--ESKLTS 129
           L ++KREQS+      +KR+T+  +   ++E A ++ +   EAK      QR  +   + 
Sbjct: 309 LKQQKREQSRFYGDLMEKRRTLEEK---EQEEARLRKLRKKEAK------QRWDDRHWSQ 359

Query: 130 GKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPT 189
            KL+ +        R  + I  +G  +P+PI +++    +  +   +L+ I   G++ PT
Sbjct: 360 KKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWK----DSSLPPHILEVIDKCGYKEPT 415

Query: 190 PIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK--------QPANKGFRALIIS 241
           PIQ QAIP+ L  R+++  A TGSGKT AF IP+L+ +         + +++G  A+I++
Sbjct: 416 PIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILA 475

Query: 242 PTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLK 301
           PTRELA QI  E IK  +  G R   +    ++ +  G +     +I++ TP RLI +L+
Sbjct: 476 PTRELAQQIEEETIKFGKPLGIRTVAVI-GGISREDQGFRLRMGCEIVIATPGRLIDVLE 534

Query: 302 QDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIF---------------------- 339
                + L+   ++V+DE+D++ +    GF   +  I                       
Sbjct: 535 NRY--LVLSRCTYVVLDEADRMID---MGFEPDVQKILEHMPVSNQKPDTDEAEDPEKML 589

Query: 340 --LACTSHKVRRA-MFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSE 396
                  HK R+  MF+AT    VE+  +  L     V IG+     E VEQ++ F+ SE
Sbjct: 590 ANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKV-FLMSE 648

Query: 397 TGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVH 456
           + K   +  ++++GF+PP+++FV   +    L   L   G N   +H  + Q+QR+  + 
Sbjct: 649 SEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALS 708

Query: 457 SFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFF 516
           + +AG   +L+ T +  RGID + V++V+NYD   +  +YIHRIGRTGRAG  G AITF 
Sbjct: 709 NLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFL 768

Query: 517 TEDDKPLLRSVANVIQQ---AGCP 537
           T++D  +   +   I +   + CP
Sbjct: 769 TKEDSAVFYELKQAILESPVSSCP 792


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  207 bits (527), Expect = 2e-53
 Identities = 167/557 (29%), Positives = 274/557 (49%), Gaps = 49/557 (8%)

Query: 7   FRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLD-FFGNKKSVPGVCGASQTH 65
           +RR G G+      F      F +G    D D  E +Q     FG+++ V    G   T 
Sbjct: 145 YRRGGRGS------FRGCRGGFGLGSPNNDLDPDECMQRTGGLFGSRRPVLSGTGNGDTS 198

Query: 66  QK------PQNGEK--KEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIE 117
           Q        + G K   EE +T   +   K + +   S   S  +G  + ++     + E
Sbjct: 199 QSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGES---SDTQGPKVTYIPPPPPEDE 255

Query: 118 DKKVQR-ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRL 176
           D      ++ +   K + +  E            V G D P  I TF++ +    +N+  
Sbjct: 256 DSIFAHYQTGINFDKYDTILVE------------VSGHDAPPAILTFEEANLCQTLNN-- 301

Query: 177 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFR 236
             NI  AG+   TP+Q  +IP++L GR+L+A A TGSGKT AF +PIL  +        R
Sbjct: 302 --NIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASR 359

Query: 237 --------ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
                    +I++PTREL +QI+ E  K S GT  R  +I+           +  +  +I
Sbjct: 360 FKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIR-QIVQGCNI 418

Query: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348
           L  TP RL+ ++ ++  G  L  +++LV+DE+D++ + G      +L S     +  + +
Sbjct: 419 LCATPGRLMDIIGKEKIG--LKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQ 476

Query: 349 RAMFSATFAYDVEQWCKLNL-DNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELV 407
             MFSATF  ++++     L  N + V++G    A   V+Q +L VG +  K   + E++
Sbjct: 477 TLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG-QFSKREKLVEIL 535

Query: 408 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
           +   +   +VFV++ ++A  +   L  E I+   IH +R Q++R+  +  FR GK  VL+
Sbjct: 536 RNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLV 595

Query: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFF-TEDDKPLLRS 526
            T++ ARG+D + V  VIN+D P++  EY+HRIGRTGR GN G+AI+FF  E D  L + 
Sbjct: 596 ATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQP 655

Query: 527 VANVIQQAGCPVPEYIK 543
           +  V+  A   VP +++
Sbjct: 656 LVKVLTDAQQDVPAWLE 672


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  207 bits (527), Expect = 2e-53
 Identities = 167/557 (29%), Positives = 274/557 (49%), Gaps = 49/557 (8%)

Query: 7   FRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLD-FFGNKKSVPGVCGASQTH 65
           +RR G G+      F      F +G    D D  E +Q     FG+++ V    G   T 
Sbjct: 145 YRRGGRGS------FRGCRGGFGLGSPNNDLDPDECMQRTGGLFGSRRPVLSGTGNGDTS 198

Query: 66  QK------PQNGEK--KEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIE 117
           Q        + G K   EE +T   +   K + +   S   S  +G  + ++     + E
Sbjct: 199 QSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGES---SDTQGPKVTYIPPPPPEDE 255

Query: 118 DKKVQR-ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRL 176
           D      ++ +   K + +  E            V G D P  I TF++ +    +N+  
Sbjct: 256 DSIFAHYQTGINFDKYDTILVE------------VSGHDAPPAILTFEEANLCQTLNN-- 301

Query: 177 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFR 236
             NI  AG+   TP+Q  +IP++L GR+L+A A TGSGKT AF +PIL  +        R
Sbjct: 302 --NIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASR 359

Query: 237 --------ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
                    +I++PTREL +QI+ E  K S GT  R  +I+           +  +  +I
Sbjct: 360 FKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIR-QIVQGCNI 418

Query: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348
           L  TP RL+ ++ ++  G  L  +++LV+DE+D++ + G      +L S     +  + +
Sbjct: 419 LCATPGRLMDIIGKEKIG--LKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQ 476

Query: 349 RAMFSATFAYDVEQWCKLNL-DNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELV 407
             MFSATF  ++++     L  N + V++G    A   V+Q +L VG +  K   + E++
Sbjct: 477 TLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG-QFSKREKLVEIL 535

Query: 408 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
           +   +   +VFV++ ++A  +   L  E I+   IH +R Q++R+  +  FR GK  VL+
Sbjct: 536 RNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLV 595

Query: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFF-TEDDKPLLRS 526
            T++ ARG+D + V  VIN+D P++  EY+HRIGRTGR GN G+AI+FF  E D  L + 
Sbjct: 596 ATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQP 655

Query: 527 VANVIQQAGCPVPEYIK 543
           +  V+  A   VP +++
Sbjct: 656 LVKVLTDAQQDVPAWLE 672


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  206 bits (524), Expect = 5e-53
 Identities = 141/440 (32%), Positives = 232/440 (52%), Gaps = 34/440 (7%)

Query: 124 ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 183
           E +L SG    +  EK + +     +   G++ P  I  F  +D    +   ++ NI   
Sbjct: 145 EQELFSGGNTGINFEKYDDI----PVEATGSNCPPHIENFSDID----MGEIIMGNIELT 196

Query: 184 GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 231
            +  PTP+Q  AIP++   R+L+A A TGSGKT AF +PIL Q+            K+  
Sbjct: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256

Query: 232 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 286
             G R     +L+++PTRELA QI+ E  K S  +  R  +++  A   ++      +  
Sbjct: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 315

Query: 287 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 346
            +LV TP RL+ ++++   G+D    ++LV+DE+D++ +    GF  Q+  I    T   
Sbjct: 316 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 370

Query: 347 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 403
             VR  M FSATF  +++   +  LD  I +++G   S  E + Q++++V     +   +
Sbjct: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430

Query: 404 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 463
             L   G +   LVFV++ + A  L   L +EG     IH +R+Q+ R+  +H FR+GK 
Sbjct: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490

Query: 464 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 523
            +L+ TA+ ARG+D   V  VIN+D P+   EY+HRIGRTGR GN G A +FF E +  +
Sbjct: 491 PILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNI 550

Query: 524 LRSVANVIQQAGCPVPEYIK 543
            + + +++ +A   VP +++
Sbjct: 551 TKDLLDLLVEAKQEVPSWLE 570


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  206 bits (524), Expect = 5e-53
 Identities = 141/440 (32%), Positives = 232/440 (52%), Gaps = 34/440 (7%)

Query: 124 ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 183
           E +L SG    +  EK + +     +   G++ P  I  F  +D    +   ++ NI   
Sbjct: 145 EQELFSGGNTGINFEKYDDI----PVEATGSNCPPHIENFSDID----MGEIIMGNIELT 196

Query: 184 GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 231
            +  PTP+Q  AIP++   R+L+A A TGSGKT AF +PIL Q+            K+  
Sbjct: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256

Query: 232 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 286
             G R     +L+++PTRELA QI+ E  K S  +  R  +++  A   ++      +  
Sbjct: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 315

Query: 287 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 346
            +LV TP RL+ ++++   G+D    ++LV+DE+D++ +    GF  Q+  I    T   
Sbjct: 316 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 370

Query: 347 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 403
             VR  M FSATF  +++   +  LD  I +++G   S  E + Q++++V     +   +
Sbjct: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430

Query: 404 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 463
             L   G +   LVFV++ + A  L   L +EG     IH +R+Q+ R+  +H FR+GK 
Sbjct: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490

Query: 464 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 523
            +L+ TA+ ARG+D   V  VIN+D P+   EY+HRIGRTGR GN G A +FF E +  +
Sbjct: 491 PILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNI 550

Query: 524 LRSVANVIQQAGCPVPEYIK 543
            + + +++ +A   VP +++
Sbjct: 551 TKDLLDLLVEAKQEVPSWLE 570


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  206 bits (523), Expect = 6e-53
 Identities = 137/405 (33%), Positives = 223/405 (55%), Gaps = 18/405 (4%)

Query: 149 IHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLAS 208
           + V G D P  I TF++ +    +N+    NI  AG+   TP+Q  +IP++L GR+L+A 
Sbjct: 242 VEVSGHDAPPAILTFEEANLCQTLNN----NIAKAGYTKLTPVQKYSIPIILAGRDLMAC 297

Query: 209 APTGSGKTLAFSIPILMQLKQPANKGFR--------ALIISPTRELASQIHRELIKISEG 260
           A TGSGKT AF +PIL  +        R         +I++PTREL +QI+ E  K S G
Sbjct: 298 AQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFG 357

Query: 261 TGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDES 320
           T  R  +I+           +  +  +IL  TP RL+ ++ ++  G  L  +++LV+DE+
Sbjct: 358 TCVRAVVIYGGTQLGHSIR-QIVQGCNILCATPGRLMDIIGKEKIG--LKQIKYLVLDEA 414

Query: 321 DKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNL-DNVISVSIGAR 379
           D++ + G      +L S     +  + +  MFSATF  ++++     L  N + V++G  
Sbjct: 415 DRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQV 474

Query: 380 NSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINV 439
             A   V+Q +L VG +  K   + E+++   +   +VFV++ ++A  +   L  E I+ 
Sbjct: 475 GGACRDVQQTVLQVG-QFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKIST 533

Query: 440 DVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHR 499
             IH +R Q++R+  +  FR GK  VL+ T++ ARG+D + V  VIN+D P++  EY+HR
Sbjct: 534 TSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHR 593

Query: 500 IGRTGRAGNKGKAITFF-TEDDKPLLRSVANVIQQAGCPVPEYIK 543
           IGRTGR GN G+AI+FF  E D  L + +  V+  A   VP +++
Sbjct: 594 IGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLE 638


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  205 bits (521), Expect = 1e-52
 Identities = 144/467 (30%), Positives = 240/467 (51%), Gaps = 38/467 (8%)

Query: 101 EEGATIQWMSSVEAKIEDKKV----QRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDL 156
           E G   +W    +     K +    + E +L SG    +  EK + +     +   G + 
Sbjct: 120 ERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDI----PVEATGNNC 175

Query: 157 PDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKT 216
           P  I +F  ++    +   ++ NI    +  PTP+Q  AIP++   R+L+A A TGSGKT
Sbjct: 176 PPHIESFSDVE----MGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKT 231

Query: 217 LAFSIPILMQL------------KQPANKGFR-----ALIISPTRELASQIHRELIKISE 259
            AF +PIL Q+            K+    G R     +L+++PTRELA QI+ E  K S 
Sbjct: 232 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 291

Query: 260 GTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDE 319
            +  R  +++  A   ++      +   +LV TP RL+ ++++   G+D    ++LV+DE
Sbjct: 292 RSRVRPCVVYGGADIGQQIRDLE-RGCHLLVATPGRLVDMMERGKIGLDFC--KYLVLDE 348

Query: 320 SDKLFEDGKTGFRDQLASIFLACTSHK--VRRAM-FSATFAYDVEQWCKLNLDNVISVSI 376
           +D++ +    GF  Q+  I    T     VR  M FSATF  +++   +  LD  I +++
Sbjct: 349 ADRMLD---MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 405

Query: 377 GARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEG 436
           G   S  E + Q++++V     +   +  L   G +   LVFV++ + A  L   L +EG
Sbjct: 406 GRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEG 465

Query: 437 INVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEY 496
                IH +R+Q+ R+  +H FR+GK  +L+ TA+ ARG+D   V  VIN+D P+   EY
Sbjct: 466 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEY 525

Query: 497 IHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIK 543
           +HRIGRTGR GN G A +FF E +  + + + +++ +A   VP +++
Sbjct: 526 VHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLE 572


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  201 bits (511), Expect = 2e-51
 Identities = 140/488 (28%), Positives = 249/488 (51%), Gaps = 28/488 (5%)

Query: 69  QNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKKVQRESKLT 128
           Q+ ++K E+  E  +E+  K+ + +   +A   EG  +  +  +   I      + S   
Sbjct: 92  QHLKEKAEARKESAKEKQLKEEEKILESVA---EGRALMSVKEMAKGITYDDPIKTSWTP 148

Query: 129 SGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMP 188
              + ++ +E+   +R K+ I V+G  +P PI +F+++    K  + +L+ +   G   P
Sbjct: 149 PRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEM----KFPAAILRGLKKKGIHHP 204

Query: 189 TPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM-------QLKQPANKGFRALIIS 241
           TPIQ+Q IP +L GR+++  A TGSGKTL F++P++M       +L     +G   LII 
Sbjct: 205 TPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIIC 264

Query: 242 PTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKK-----FDILVTTPNRL 296
           P+RELA Q H  L             + + A+       K   +       ++V TP RL
Sbjct: 265 PSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRL 324

Query: 297 IYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATF 356
           + LL++    +D+    +L +DE+D++ +    GF   + +IF      + +  +FSAT 
Sbjct: 325 MDLLQKKMVSLDIC--RYLALDEADRMID---MGFEGDIRTIFSYFKGQR-QTLLFSATM 378

Query: 357 AYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVL 416
              ++ + K  L   +++++G   +A   V QE+ +V  E  K++ + E ++K   PPVL
Sbjct: 379 PKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYV-KEEAKMVYLLECLQKT-PPPVL 436

Query: 417 VFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGI 476
           +F +       +   L+ +G+    IH  + Q++R   + +FR GK  VL+ T + ++G+
Sbjct: 437 IFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGL 496

Query: 477 DFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED-DKPLLRSVANVIQQAG 535
           DF  +  VINYD P     Y+HRIGRTGR+GN G A TF  +  D+ +L  +  ++ +A 
Sbjct: 497 DFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAK 556

Query: 536 CPVPEYIK 543
             VP  ++
Sbjct: 557 QKVPPVLQ 564


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  195 bits (496), Expect = 9e-50
 Identities = 149/547 (27%), Positives = 266/547 (48%), Gaps = 53/547 (9%)

Query: 72  EKKEESLTERKREQSKKKRKTMTSEIAS--------QEEGATIQWMSSVEAKIEDKKVQR 123
           +K+  +  + K E+ +KKRKT   E  S         +EG+  +    ++   E+     
Sbjct: 110 KKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDE 169

Query: 124 --ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLD-----QEYKINSRL 176
             E+  +S     L K     ++++ K   +G +         Q D     Q+  ++  L
Sbjct: 170 ASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPL 229

Query: 177 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKG-- 234
           L+ I   GF+ PTPIQ   IPV L G+++ A A TG+GKT AF++P+L +L     +   
Sbjct: 230 LKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPV 289

Query: 235 FRALIISPTRELASQIHRELIKISEGTGFRIHMIH-----KAAVAAKKFGPKSSKKFDIL 289
            R L++ PTREL  Q+H    ++++       +       K+  AA +  P      DIL
Sbjct: 290 TRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAP------DIL 343

Query: 290 VTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRR 349
           + TP RLI  L  + P   L+S+E L++DE+D++ ++    F +Q+  I   C+ H+ + 
Sbjct: 344 IATPGRLIDHL-HNCPSFHLSSIEVLILDEADRMLDEY---FEEQMKEIIRMCSHHR-QT 398

Query: 350 AMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFV--GSETGKLLAMRELV 407
            +FSAT   +V+    ++L N + + + +       + QE + +    E  +   +  L+
Sbjct: 399 MLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALL 458

Query: 408 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
            + F   V++F Q+ ++A  +   L   G+ V  +H   +Q QR   +  F+  +I +L+
Sbjct: 459 TRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILV 518

Query: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 527
            T + ARG+D +GV  VIN+  P +   Y+HR+GRT RAG  G++++   ED++ +L+  
Sbjct: 519 ATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLK-- 576

Query: 528 ANVIQQAGCPV------PEYIKGFQKLLSKQKKKMI---------KKPLERESISTTPKC 572
             +++ A  PV       + I  F+  + K +K +          K+  + E+   T K 
Sbjct: 577 -EIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKR 635

Query: 573 FLEKAKD 579
            LEK K+
Sbjct: 636 LLEKGKE 642


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  185 bits (470), Expect = 9e-47
 Identities = 156/538 (28%), Positives = 255/538 (47%), Gaps = 54/538 (10%)

Query: 49  FGNKKSVPGVCGASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQW 108
           FGN++       A +T  + Q     E S+ +    Q+   R    ++I  + E  +  W
Sbjct: 96  FGNREMKAKAKAAIETLIRKQESYNSESSV-DNAASQTPIGRNLGRNDIVGEAEPLS-NW 153

Query: 109 MSSVEAKIEDKK--------VQR----ESKLTSGKLE----NLRKEKINFLRNKHKIHVQ 152
                A +E +K        V++    ESK TS   E    N RKE  N   +  K   +
Sbjct: 154 DRIRAAVVECEKRKWADLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEK 213

Query: 153 GTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTG 212
              +P P   F+   Q+Y     LL++I+  G   PTPIQ QA P++L G +L+  A TG
Sbjct: 214 RL-IPKPTCRFKDAFQQYP---DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTG 269

Query: 213 SGKTLAFSIPILMQL-KQPANKGFR----ALIISPTRELASQIHRELIKISEGTGFRIHM 267
           +GKTL++ +P  + L  QP ++  R     L+++PTRELA  +  E  K S         
Sbjct: 270 TGKTLSYLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYS--------- 320

Query: 268 IHKAAVAAKKFGPKS--------SKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDE 319
            +K   +   +G ++        SK  DI++ TP RL  L   +   ++L S+ +LV+DE
Sbjct: 321 -YKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMNN--SVNLRSITYLVIDE 377

Query: 320 SDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGAR 379
           +DK+ +     F  Q+  I L     + +  M SAT+   V Q     L + + V +G  
Sbjct: 378 ADKMLD---MEFEPQIRKILLDVRPDR-QTVMTSATWPDTVRQLALSYLKDPMIVYVGNL 433

Query: 380 NS-AVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGIN 438
           N  AV TV+Q ++    +  + L    +     N  V++FV     A +L  +   +GI+
Sbjct: 434 NLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADDLSSDFNIQGIS 493

Query: 439 VDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIH 498
            + +H    Q  ++  V  F++G I +LI T +++RG+D   V  V NYDFP +   Y+H
Sbjct: 494 AESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVH 553

Query: 499 RIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE--YIKGFQKLLSKQKK 554
           R+G  GR G  G ++T  T+ D  +   +  ++ +A   VPE   +   Q  L++QK+
Sbjct: 554 RVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVMAEQYKLNQQKR 611


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  183 bits (464), Expect = 4e-46
 Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%)

Query: 131 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 190
           ++ NL  +++  LR+K  + V G   P P ++F      +  + +L+  I  + +  PTP
Sbjct: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278

Query: 191 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 246
           IQ Q +PV L GR+++  A TGSGKT AF  P+L+    Q +     G  A+I+ PTREL
Sbjct: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338

Query: 247 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 306
             QIH E  +  +    R   ++      ++      +  +I+V TP RLI  +K+    
Sbjct: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395

Query: 307 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 366
            +L  V +LV DE+D++F+    GF  Q+ SI       + +  +FSATF   +E+  + 
Sbjct: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451

Query: 367 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 424
            L + I V  G    A E V Q  E+L  G      L  R LV+   +  VL+FV     
Sbjct: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510

Query: 425 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 484
           A+EL + L  EG N+ ++H +  Q +R+  +  F+   I VL+ T + ARG+D   +  V
Sbjct: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570

Query: 485 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 520
           INYD       + HRIGRTGRAG KG A T  T  D
Sbjct: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  183 bits (464), Expect = 4e-46
 Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%)

Query: 131 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 190
           ++ NL  +++  LR+K  + V G   P P ++F      +  + +L+  I  + +  PTP
Sbjct: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278

Query: 191 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 246
           IQ Q +PV L GR+++  A TGSGKT AF  P+L+    Q +     G  A+I+ PTREL
Sbjct: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338

Query: 247 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 306
             QIH E  +  +    R   ++      ++      +  +I+V TP RLI  +K+    
Sbjct: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395

Query: 307 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 366
            +L  V +LV DE+D++F+    GF  Q+ SI       + +  +FSATF   +E+  + 
Sbjct: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451

Query: 367 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 424
            L + I V  G    A E V Q  E+L  G      L  R LV+   +  VL+FV     
Sbjct: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510

Query: 425 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 484
           A+EL + L  EG N+ ++H +  Q +R+  +  F+   I VL+ T + ARG+D   +  V
Sbjct: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570

Query: 485 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 520
           INYD       + HRIGRTGRAG KG A T  T  D
Sbjct: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  182 bits (463), Expect = 6e-46
 Identities = 125/425 (29%), Positives = 221/425 (52%), Gaps = 23/425 (5%)

Query: 120 KVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDL-PDPIATFQQLDQEYKINSRLLQ 178
           K ++   +   ++  L   +++ LR K +I V+G D+ P P+  F   +        ++ 
Sbjct: 129 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHAN----FPQYVMD 184

Query: 179 NILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK-QP---ANKG 234
            ++D  F  PTPIQ Q  P+ L GR+++  A TGSGKTLA+ +P ++ +  QP      G
Sbjct: 185 VLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDG 244

Query: 235 FRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPN 294
              L+++PTRELA Q+ +      + +  +   I+  A    +      +  +I + TP 
Sbjct: 245 PICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE-RGVEICIATPG 303

Query: 295 RLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSA 354
           RLI  L+      +L    +LV+DE+D++ +    GF  Q+  I       + +  M+SA
Sbjct: 304 RLIDFLESGKT--NLRRCTYLVLDEADRMLD---MGFEPQIRKIVDQIRPDR-QTLMWSA 357

Query: 355 TFAYDVEQWCKLNLDNVISVSIG-----ARNSAVETVEQELLFVGSETGKLLAMRELVKK 409
           T+  +V Q  +  L +   +++G     A ++ ++ V+  +     +  KL+ + E +  
Sbjct: 358 TWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVD--VCMESEKDHKLIQLMEEIMA 415

Query: 410 GFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICT 469
                 ++FV++  R  +L   +  +G     IH +++Q +RD  ++ FR+GK  +LI T
Sbjct: 416 EKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIAT 475

Query: 470 ALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVAN 529
            + +RG+D + V  VINYD+P SS +Y+HRIGRT R+ NKG A TFFT  +    R +  
Sbjct: 476 DVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIK 535

Query: 530 VIQQA 534
           V+++A
Sbjct: 536 VLEEA 540


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  182 bits (463), Expect = 6e-46
 Identities = 125/425 (29%), Positives = 221/425 (52%), Gaps = 23/425 (5%)

Query: 120 KVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDL-PDPIATFQQLDQEYKINSRLLQ 178
           K ++   +   ++  L   +++ LR K +I V+G D+ P P+  F   +        ++ 
Sbjct: 129 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHAN----FPQYVMD 184

Query: 179 NILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK-QP---ANKG 234
            ++D  F  PTPIQ Q  P+ L GR+++  A TGSGKTLA+ +P ++ +  QP      G
Sbjct: 185 VLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDG 244

Query: 235 FRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPN 294
              L+++PTRELA Q+ +      + +  +   I+  A    +      +  +I + TP 
Sbjct: 245 PICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE-RGVEICIATPG 303

Query: 295 RLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSA 354
           RLI  L+      +L    +LV+DE+D++ +    GF  Q+  I       + +  M+SA
Sbjct: 304 RLIDFLESGKT--NLRRCTYLVLDEADRMLD---MGFEPQIRKIVDQIRPDR-QTLMWSA 357

Query: 355 TFAYDVEQWCKLNLDNVISVSIG-----ARNSAVETVEQELLFVGSETGKLLAMRELVKK 409
           T+  +V Q  +  L +   +++G     A ++ ++ V+  +     +  KL+ + E +  
Sbjct: 358 TWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVD--VCMESEKDHKLIQLMEEIMA 415

Query: 410 GFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICT 469
                 ++FV++  R  +L   +  +G     IH +++Q +RD  ++ FR+GK  +LI T
Sbjct: 416 EKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIAT 475

Query: 470 ALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVAN 529
            + +RG+D + V  VINYD+P SS +Y+HRIGRT R+ NKG A TFFT  +    R +  
Sbjct: 476 DVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIK 535

Query: 530 VIQQA 534
           V+++A
Sbjct: 536 VLEEA 540


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  181 bits (460), Expect = 1e-45
 Identities = 119/362 (32%), Positives = 192/362 (53%), Gaps = 13/362 (3%)

Query: 169 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 228
           +  +   LL+ I   GF+ P+ IQ +AI   + G +++A A +G+GKT  F+I IL QL+
Sbjct: 37  DMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLE 96

Query: 229 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
               K  +AL+++PTRELA QI + ++ + +  G   H          +     ++   I
Sbjct: 97  IEF-KETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHI 155

Query: 289 LVTTPNRLIYLLKQDPPGIDLASVEWL---VVDESDKLFEDGKTGFRDQLASIFLACTSH 345
           +V TP R+  +L +        S +W+   V+DE+D++      GF+DQ+  IF    + 
Sbjct: 156 VVGTPGRVFDMLNRR-----YLSPKWIKMFVLDEADEMLS---RGFKDQIYEIFQKLNT- 206

Query: 346 KVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRE 405
            ++  + SAT   DV +  K  + + I + +      +E ++Q  + V  E  KL  + +
Sbjct: 207 SIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCD 266

Query: 406 LVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWV 465
           L +       ++F+ +  +   L  ++      V  +H +  Q++RD  +  FR+G   V
Sbjct: 267 LYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRV 326

Query: 466 LICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLR 525
           LI T LLARGID + V+LVINYD PT+   YIHRIGR GR G KG AI F TE+DK +LR
Sbjct: 327 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386

Query: 526 SV 527
            +
Sbjct: 387 DI 388


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  179 bits (455), Expect = 5e-45
 Identities = 116/375 (30%), Positives = 199/375 (53%), Gaps = 9/375 (2%)

Query: 168 QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL 227
           ++Y +   LL  I + G++ P+PIQ ++IP+ L GR++LA A  G+GK+ A+ IP+L +L
Sbjct: 99  EDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERL 158

Query: 228 KQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFD 287
               +   +A++I PTRELA Q+ +  I++S+  G    M        +    +      
Sbjct: 159 DLKKDN-IQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 217

Query: 288 ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKV 347
           +++ TP R++ L+K+    +D   V+ +V+DE+DKL       F   +  I L    ++ 
Sbjct: 218 VVIATPGRILDLIKKGVAKVD--HVQMIVLDEADKLLSQD---FVQIMEDIILTLPKNR- 271

Query: 348 RRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELV 407
           +  ++SATF   V+++   +L     +++      ++ V Q   +V +E  K+  +  L 
Sbjct: 272 QILLYSATFPLSVQKFMNSHLQKPYEINL-MEELTLKGVTQYYAYV-TERQKVHCLNTLF 329

Query: 408 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
            +      ++F  S +R + L  ++   G +   IHA+  Q+ R+   H FR G    L+
Sbjct: 330 SRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLV 389

Query: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 527
           CT L  RGID + VN+VIN+DFP  +  Y+HRIGR+GR G+ G AI   T DD+  L+S+
Sbjct: 390 CTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSI 449

Query: 528 ANVIQQAGCPVPEYI 542
              +     P+P  I
Sbjct: 450 EEQLGTEIKPIPSNI 464


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  177 bits (449), Expect = 2e-44
 Identities = 116/359 (32%), Positives = 188/359 (52%), Gaps = 7/359 (1%)

Query: 169 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 228
           +  ++  LL+ I   GF+ P+ IQ +AI   + G +++A A +G+GKT  F+I IL Q++
Sbjct: 36  DMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIE 95

Query: 229 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
               K  +AL+++PTRELA QI + ++ + +  G   H          +      +   I
Sbjct: 96  LDL-KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHI 154

Query: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348
           +V TP R+  +L +    +    ++  V+DE+D++      GF+DQ+  IF    S+  +
Sbjct: 155 IVGTPGRVFDMLNRRY--LSPKYIKMFVLDEADEMLS---RGFKDQIYDIFQKLNSN-TQ 208

Query: 349 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 408
             + SAT   DV +  K  + + I + +      +E + Q  + V  E  KL  + +L +
Sbjct: 209 VVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYE 268

Query: 409 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 468
                  ++F+ +  +   L  ++      V  +H +  Q++RD  +  FR+G   VLI 
Sbjct: 269 TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328

Query: 469 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 527
           T LLARGID + V+LVINYD PT+   YIHRIGR GR G KG AI   TE+DK  LR +
Sbjct: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  175 bits (444), Expect = 9e-44
 Identities = 116/387 (29%), Positives = 205/387 (52%), Gaps = 16/387 (4%)

Query: 150 HVQGTDLPDPIATFQQLD--QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLA 207
           H   T+   PI   ++    ++  +   L +     G+  PT IQ++AIP+ L GR+++ 
Sbjct: 7   HDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIG 66

Query: 208 SAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHM 267
            A TGSGKT AF++PIL  L +   + F AL+++PTRELA QI  +   +    G +  +
Sbjct: 67  LAETGSGKTGAFALPILNALLETPQRLF-ALVLTPTRELAFQISEQFEALGSSIGVQSAV 125

Query: 268 IHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDG 327
           I    + +       +KK  I++ TP RLI  L ++  G +L ++++LV+DE+D++    
Sbjct: 126 I-VGGIDSMSQSLALAKKPHIIIATPGRLIDHL-ENTKGFNLRALKYLVMDEADRILN-- 181

Query: 328 KTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVE 387
              F  ++  I       + +  +FSAT    V++  +  L N +  ++ ++   VE ++
Sbjct: 182 -MDFETEVDKILKVIPRDR-KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQ 239

Query: 388 QELLFVGS---ETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHA 444
           Q  +F+ S   +T  +  + EL    F    ++F  +    +     L   G     +H 
Sbjct: 240 QYYIFIPSKFKDTYLVYILNELAGNSF----MIFCSTCNNTQRTALLLRNLGFTAIPLHG 295

Query: 445 ERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTG 504
           + +Q +R  +++ F+A    +L+ T + +RG+D   V++V+N+D PT S +YIHR+GRT 
Sbjct: 296 QMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTA 355

Query: 505 RAGNKGKAITFFTEDDKPLLRSVANVI 531
           RAG  GKAITF T+ D  L + + ++I
Sbjct: 356 RAGRSGKAITFVTQYDVELFQRIEHLI 382


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  172 bits (436), Expect = 8e-43
 Identities = 123/404 (30%), Positives = 208/404 (51%), Gaps = 18/404 (4%)

Query: 138 EKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIP 197
           +++   R   +I V+G + P P+  F     E    + ++  I    F  PT IQ Q  P
Sbjct: 71  QEVETYRRSKEITVRGHNCPKPVLNFY----EANFPANVMDVIARQNFTEPTAIQAQGWP 126

Query: 198 VMLHGRELLASAPTGSGKTLAFSIPILMQLK-QP---ANKGFRALIISPTRELASQIHRE 253
           V L G +++  A TGSGKTL++ +P ++ +  QP      G   L+++PTRELA Q+ + 
Sbjct: 127 VALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQV 186

Query: 254 LIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVE 313
             +       +   I+  A    +      +  +I + TP RLI  L+      +L    
Sbjct: 187 AAEYCRACRLKSTCIYGGAPKGPQIRDLE-RGVEICIATPGRLIDFLECGKT--NLRRTT 243

Query: 314 WLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVIS 373
           +LV+DE+D++ +    GF  Q+  I       + +  M+SAT+  +V Q  +  L + I 
Sbjct: 244 YLVLDEADRMLD---MGFEPQIRKIVDQIRPDR-QTLMWSATWPKEVRQLAEDFLKDYIH 299

Query: 374 VSIGARN-SAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFH 430
           ++IGA   SA   + Q  ++     +  KL+ + E +        +VFV++  R  EL  
Sbjct: 300 INIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTR 359

Query: 431 ELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFP 490
           ++  +G     IH +++QQ+RD  ++ F+ GK  +LI T + +RG+D + V  VINYD+P
Sbjct: 360 KMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYP 419

Query: 491 TSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQA 534
            SS +YIHRIGRT R+   G A TFFT ++   +  + +V+++A
Sbjct: 420 NSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREA 463


>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
           sapiens]
          Length = 670

 Score =  172 bits (435), Expect = 1e-42
 Identities = 149/503 (29%), Positives = 243/503 (48%), Gaps = 39/503 (7%)

Query: 70  NGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDK-KVQRESKLT 128
           NGE   +S     +++ KKKRK +       ++           AK E+K K + ES  T
Sbjct: 95  NGEAAMQSSNSESKKKKKKKRKMVNDAEPDTKK-----------AKTENKGKSEEESAET 143

Query: 129 SGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMP 188
           + + EN   EK +   ++ ++      L               +N   L+ I + GF   
Sbjct: 144 TKETEN-NVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNM 202

Query: 189 TPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP---ILMQLKQPANKGFRALIISPTRE 245
           T IQ ++I  +L GR+LLA+A TGSGKTLAF IP   ++++L+     G   LI+SPTRE
Sbjct: 203 TEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTRE 262

Query: 246 LASQ---IHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQ 302
           LA Q   + +EL+     T   I      +  A+K G       +I+V TP RL+  + Q
Sbjct: 263 LAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLG----NGINIIVATPGRLLDHM-Q 317

Query: 303 DPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQ 362
           + PG    +++ LV+DE+D++ +    GF ++L  I     + + +  +FSAT    VE 
Sbjct: 318 NTPGFMYKNLQCLVIDEADRILD---VGFEEELKQIIKLLPTRR-QTMLFSATQTRKVED 373

Query: 363 WCKLNLDN---VISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFV 419
             +++L      + V     N+ V+ +EQ  +   SE  + L +   +KK     ++VF 
Sbjct: 374 LARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEK-RFLLLFTFLKKNRKKKLMVFF 432

Query: 420 QSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFK 479
            S    K  +  L Y  + V  IH ++ Q +R  T   F       L+CT + ARG+D  
Sbjct: 433 SSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIP 492

Query: 480 GVNLVINYDFPTSSVEYIHRIGRTGRAGN-KGKAITFFTEDDKPLLRSVANVIQQAGCPV 538
            V+ ++ YD P    EYIHR+GRT R  N +G A+     ++   LR     ++Q+  P+
Sbjct: 493 EVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLR----YLKQSKVPL 548

Query: 539 PEYIKGFQKL--LSKQKKKMIKK 559
            E+   + K+  +  Q +K+I+K
Sbjct: 549 SEFDFSWSKISDIQSQLEKLIEK 571


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  163 bits (413), Expect = 4e-40
 Identities = 116/365 (31%), Positives = 184/365 (50%), Gaps = 15/365 (4%)

Query: 163 FQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP 222
           FQ +   Y +     + I+  G+++PTPIQ + IPV+L G++++A A TGSGKT  F +P
Sbjct: 98  FQSMGLSYPV----FKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLP 153

Query: 223 ILMQLK-QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPK 281
           +  +LK   A  G RALI+SPTRELA Q  +   ++ + TG +  +I        +F   
Sbjct: 154 MFERLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAAL 213

Query: 282 SSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLA 341
                DI++ TP RL+++  +    + L SVE++V DE+D+LFE    GF +QL  I +A
Sbjct: 214 HENP-DIIIATPGRLVHVAVE--MSLKLQSVEYVVFDEADRLFE---MGFAEQLQEI-IA 266

Query: 342 CTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLL 401
                 +  +FSAT    + ++ +  L   + + +       E ++     V  +T K  
Sbjct: 267 RLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDT-KAA 325

Query: 402 AMRELVKKGFNPP--VLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFR 459
            +  L+     P    +VFV +   A+ L   L  + ++   I++      R   +  F 
Sbjct: 326 VLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFT 385

Query: 460 AGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED 519
            GK   LI T L ARG+D   ++ VINY FP     ++HR+GR  RAG  G A +    D
Sbjct: 386 LGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPD 445

Query: 520 DKPLL 524
           + P L
Sbjct: 446 EIPYL 450


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  163 bits (413), Expect = 4e-40
 Identities = 116/365 (31%), Positives = 184/365 (50%), Gaps = 15/365 (4%)

Query: 163 FQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP 222
           FQ +   Y +     + I+  G+++PTPIQ + IPV+L G++++A A TGSGKT  F +P
Sbjct: 98  FQSMGLSYPV----FKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLP 153

Query: 223 ILMQLK-QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPK 281
           +  +LK   A  G RALI+SPTRELA Q  +   ++ + TG +  +I        +F   
Sbjct: 154 MFERLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAAL 213

Query: 282 SSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLA 341
                DI++ TP RL+++  +    + L SVE++V DE+D+LFE    GF +QL  I +A
Sbjct: 214 HENP-DIIIATPGRLVHVAVE--MSLKLQSVEYVVFDEADRLFE---MGFAEQLQEI-IA 266

Query: 342 CTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLL 401
                 +  +FSAT    + ++ +  L   + + +       E ++     V  +T K  
Sbjct: 267 RLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDT-KAA 325

Query: 402 AMRELVKKGFNPP--VLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFR 459
            +  L+     P    +VFV +   A+ L   L  + ++   I++      R   +  F 
Sbjct: 326 VLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFT 385

Query: 460 AGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED 519
            GK   LI T L ARG+D   ++ VINY FP     ++HR+GR  RAG  G A +    D
Sbjct: 386 LGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPD 445

Query: 520 DKPLL 524
           + P L
Sbjct: 446 EIPYL 450


>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
           sapiens]
          Length = 875

 Score =  159 bits (403), Expect = 5e-39
 Identities = 126/467 (26%), Positives = 225/467 (48%), Gaps = 33/467 (7%)

Query: 117 EDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRL 176
           ++KK Q   +L   + +  R+     ++N  KI+V      + I  F     ++ ++ + 
Sbjct: 31  QNKKKQLRKQLKKPEWQVERESISRLMQNYEKINV------NEITRFS----DFPLSKKT 80

Query: 177 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPIL---MQLKQPANK 233
           L+ + +A +++ T IQ Q I + L G+++L +A TGSGKTLAF +P+L    +L+  +  
Sbjct: 81  LKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTD 140

Query: 234 GFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSK--KFDILVT 291
           G   LIISPTRELA Q    L K+ +   F   +I    +  K    ++ +    +ILV 
Sbjct: 141 GLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLI----IGGKDLKHEAERINNINILVC 196

Query: 292 TPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAM 351
           TP RL+  +  +        ++ LV+DE+D++ +    GF D + ++ +     K +  +
Sbjct: 197 TPGRLLQHM-DETVSFHATDLQMLVLDEADRILD---MGFADTMNAV-IENLPKKRQTLL 251

Query: 352 FSATFAYDVEQWCKLNLDN--VISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKK 409
           FSAT    V+   +L+L N   + V   A+ S   T+EQ  +    +  K+  +   ++ 
Sbjct: 252 FSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQ-KISVLYSFLRS 310

Query: 410 GFNPPVLVFVQSIERAKELFHEL--IYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
                 +VF  S +  + L+     +  G+++  +H  + Q +R    + F   +  VL 
Sbjct: 311 HLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAVLF 370

Query: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 527
            T + ARG+DF  VN V+ +D P  +  YIHR GRT R    G+A+      +K +++  
Sbjct: 371 ATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEKAMVQQ- 429

Query: 528 ANVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFL 574
              + Q   PV E     +KL+  QKK       +++      +CF+
Sbjct: 430 ---LLQKKVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFV 473


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  157 bits (396), Expect = 3e-38
 Identities = 107/384 (27%), Positives = 196/384 (51%), Gaps = 20/384 (5%)

Query: 148 KIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLA 207
           K+  + ++  D   TF  +     +   LL+ I   GF+ P+ IQ +AI  ++ GR+++A
Sbjct: 25  KVEFETSEEVDVTPTFDTMG----LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIA 80

Query: 208 SAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHM 267
            + +G+GKT  FSI +L  L     +  +ALI++PTRELA QI + L+ + +    + H 
Sbjct: 81  QSQSGTGKTATFSISVLQCLDIQVRET-QALILAPTRELAVQIQKGLLALGDYMNVQCH- 138

Query: 268 IHKAAVAAKKFGPKSSKKFD----ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKL 323
              A +     G +  +K D    ++  TP R+  ++++    +   +++ LV+DE+D++
Sbjct: 139 ---ACIGGTNVG-EDIRKLDYGQHVVAGTPGRVFDMIRRR--SLRTRAIKMLVLDEADEM 192

Query: 324 FEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAV 383
              G   F++Q+  ++        +  + SAT  +++ +     + + I + +      +
Sbjct: 193 LNKG---FKEQIYDVYRYLPP-ATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTL 248

Query: 384 ETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIH 443
           E ++Q  + V  E  K   + +L         ++F  +  +   L  ++      V  +H
Sbjct: 249 EGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMH 308

Query: 444 AERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRT 503
            +  Q++R++ +  FR+G   VLI T + ARG+D   V+L+INYD P +   YIHRIGR+
Sbjct: 309 GDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRS 368

Query: 504 GRAGNKGKAITFFTEDDKPLLRSV 527
           GR G KG AI F   DD  +LR +
Sbjct: 369 GRYGRKGVAINFVKNDDIRILRDI 392


>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
           sapiens]
          Length = 427

 Score =  156 bits (395), Expect = 4e-38
 Identities = 110/377 (29%), Positives = 187/377 (49%), Gaps = 8/377 (2%)

Query: 168 QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL 227
           +++ +   LL+ I+D GF+ P+ +Q + IP  + G ++L  A +G GKT  F +  L Q+
Sbjct: 47  RDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQI 106

Query: 228 KQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFD 287
            +P N     L++  TRELA QI +E  + S+        +    ++ KK      K   
Sbjct: 107 -EPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCP 165

Query: 288 -ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 346
            ++V TP R++ L++       L +V+  V+DE DK+ E  +   R  +  IF   T H+
Sbjct: 166 HVVVGTPGRILALVRNR--SFSLKNVKHFVLDECDKMLE--QLDMRRDVQEIF-RLTPHE 220

Query: 347 VRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMREL 406
            +  MFSAT + D+   C+  + + + V +           Q+      ++ K   + +L
Sbjct: 221 KQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDL 280

Query: 407 VKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVL 466
           +       V++FV+S++R   L   L+ +      IH    Q++R +    F+  +  +L
Sbjct: 281 LDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRIL 340

Query: 467 ICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFT-EDDKPLLR 525
           + T L  RG+D + VN+V NYD P  S  Y+HR+ R GR G KG AITF + E+D  +L 
Sbjct: 341 VATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILN 400

Query: 526 SVANVIQQAGCPVPEYI 542
            V +  +     +PE I
Sbjct: 401 DVQDRFEVNVAELPEEI 417


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,558,663
Number of Sequences: 37866
Number of extensions: 968197
Number of successful extensions: 5551
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 105
Number of HSP's that attempted gapping in prelim test: 4685
Number of HSP's gapped (non-prelim): 726
length of query: 599
length of database: 18,247,518
effective HSP length: 108
effective length of query: 491
effective length of database: 14,157,990
effective search space: 6951573090
effective search space used: 6951573090
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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