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Search of human proteins with 38569503
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
(491 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 963 0.0
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 963 0.0
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 217 2e-56
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 216 5e-56
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 211 1e-54
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 206 4e-53
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 206 4e-53
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 206 5e-53
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 206 5e-53
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 206 5e-53
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 204 1e-52
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 200 2e-51
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 196 3e-50
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 189 4e-48
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 184 2e-46
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 183 4e-46
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 183 4e-46
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 182 5e-46
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 182 5e-46
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 181 1e-45
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 179 4e-45
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 177 2e-44
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 175 7e-44
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 172 6e-43
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 165 8e-41
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 163 3e-40
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 163 3e-40
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 159 4e-39
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 157 3e-38
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi... 156 4e-38
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 963 bits (2490), Expect = 0.0
Identities = 491/491 (100%), Positives = 491/491 (100%)
Query: 1 MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ 60
MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ
Sbjct: 1 MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ 60
Query: 61 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 120
EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK
Sbjct: 61 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 120
Query: 121 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 180
QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI
Sbjct: 121 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 180
Query: 181 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 240
LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR
Sbjct: 181 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 240
Query: 241 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 300
RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK
Sbjct: 241 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 300
Query: 301 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 360
KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC
Sbjct: 301 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 360
Query: 361 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 420
TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA
Sbjct: 361 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 420
Query: 421 NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN 480
NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN
Sbjct: 421 NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN 480
Query: 481 SKKKVALEDKS 491
SKKKVALEDKS
Sbjct: 481 SKKKVALEDKS 491
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 963 bits (2490), Expect = 0.0
Identities = 491/491 (100%), Positives = 491/491 (100%)
Query: 1 MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ 60
MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ
Sbjct: 109 MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ 168
Query: 61 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 120
EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK
Sbjct: 169 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 228
Query: 121 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 180
QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI
Sbjct: 229 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
Query: 181 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 240
LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR
Sbjct: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348
Query: 241 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 300
RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK
Sbjct: 349 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 408
Query: 301 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 360
KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC
Sbjct: 409 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 468
Query: 361 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 420
TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA
Sbjct: 469 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 528
Query: 421 NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN 480
NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN
Sbjct: 529 NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN 588
Query: 481 SKKKVALEDKS 491
SKKKVALEDKS
Sbjct: 589 SKKKVALEDKS 599
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 217 bits (553), Expect = 2e-56
Identities = 157/473 (33%), Positives = 245/473 (51%), Gaps = 40/473 (8%)
Query: 26 NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQM 85
NL++++I L+ + I VQG ++ PI F+ +N N+ +G+++PTPIQM
Sbjct: 176 NLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN----HNLKKSGYEVPTPIQM 231
Query: 86 QAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRE 145
Q IPV L GR++LASA TGSGKT AF +P++M+ + K ALI++PTRELA QI R+
Sbjct: 232 QMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFES-KTPSALILTPTRELAIQIERQ 290
Query: 146 LIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVE 205
++ G ++ + + + +++ TP RL+ ++KQ ++L V+
Sbjct: 291 AKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS--SVELCGVK 348
Query: 206 WLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVIS 265
+VVDE+D + K GF+ Q+ I L + + + SAT +EQ L N +
Sbjct: 349 IVVVDEADTML---KMGFQQQVLDI-LENIPNDCQTILVSATIPTSIEQLASQLLHNPVR 404
Query: 266 VSIGARNSAVETVEQELLFVGSETGKLLAMRELV--KKGFNPPVLVFVQSIERAKELFHE 323
+ G +N V Q +L+V + K + E++ KK F PPVLVFV + +L E
Sbjct: 405 IITGEKNLPCANVRQIILWV-EDPAKKKKLFEILNDKKLFKPPVLVFVDC-KLGADLLSE 462
Query: 324 LIYE--GINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF 381
+ + G+ IH+E++Q +R N + G V++ T +L RG+D V LV+N+D
Sbjct: 463 AVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDM 522
Query: 382 PTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLL 441
P+S EY+H+IGR GR G G AITF + K L +A ++ G +P + L
Sbjct: 523 PSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLN-SPYL 581
Query: 442 SKQKKKMIKKPLERESISTTPKCFLEKAKDKQKK---VTGQNSKKKVALEDKS 491
QK+K E+ KDKQ + VTG N + DKS
Sbjct: 582 HDQKRK-------------------EQQKDKQTQNDLVTGANLMDIIRKHDKS 615
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 216 bits (549), Expect = 5e-56
Identities = 146/454 (32%), Positives = 241/454 (53%), Gaps = 18/454 (3%)
Query: 7 KIEDKKVQRESKLTSGKLENLRKEKINFLRNKHK-IHVQGTDLPDPIATFQQLDQEYKIN 65
KIE + ++ + +L + +E++N R + + I V+G P PI ++ Q I+
Sbjct: 325 KIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCG----IS 380
Query: 66 SRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP----ILMQLKQ 121
++L ++ G++ PTPIQ QAIP ++ GR+L+ A TGSGKT+AF +P I+ Q
Sbjct: 381 MKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSL 440
Query: 122 PANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDIL 181
+G A+I++PTRELA QI +E K S+ G R+ ++ +++ + + +I+
Sbjct: 441 EEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIA-ELKRGAEII 499
Query: 182 VTTPNRLIYLLKQDPPGI-DLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 240
V TP R+I +L + + +L V ++V+DE+D++F+ GF Q+ I + +
Sbjct: 500 VCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFD---MGFEPQVMRIVDNVRPDR-Q 555
Query: 241 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 300
MFSATF +E + L I V +G R+ VEQ+++ + E L + L
Sbjct: 556 TVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGH 615
Query: 301 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 360
+ V++FV E A L +L+ +H Q RD+ ++ F+ G +L+
Sbjct: 616 YQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVA 675
Query: 361 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 420
T++ ARG+D K + LV+NY P +Y+HR GRTGRAGNKG A TF TED +
Sbjct: 676 TSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDII 735
Query: 421 NVIQQAGCPVPEYIKGFQKLLSKQKK---KMIKK 451
++ +G VP ++ Q+K K+IKK
Sbjct: 736 KALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKK 769
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 211 bits (537), Expect = 1e-54
Identities = 149/456 (32%), Positives = 242/456 (53%), Gaps = 23/456 (5%)
Query: 11 KKVQRESKLTSG----KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINS 66
K +ES TS + ++ RKE N + K + +P+P TF D ++
Sbjct: 196 KNFYKESTATSAMSKVEADSWRKENFNITWDDLK-DGEKRPIPNPTCTF---DDAFQCYP 251
Query: 67 RLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK-QPANK 125
+++NI AGFQ PTPIQ QA P++L G +L+ A TG+GKTL + +P + L QP+ K
Sbjct: 252 EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLK 311
Query: 126 GFR----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDIL 181
G R L+++PTRELA Q+ E K S G R ++ ++ + K DI+
Sbjct: 312 GQRNRPGMLVLTPTRELALQVEGECCKYSY-KGLRSVCVYGGGNRDEQI-EELKKGVDII 369
Query: 182 VTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRR 241
+ TP RL L Q ++L ++ +LV+DE+DK+ + GF Q+ I L + +
Sbjct: 370 IATPGRLNDL--QMSNFVNLKNITYLVLDEADKMLD---MGFEPQIMKILLDVRPDR-QT 423
Query: 242 AMFSATFAYDVEQWCKLNLDNVISVSIGARNS-AVETVEQELLFVGSETGKLLAMRELVK 300
M SAT+ + V + + L + V +G + AV +V+Q ++ E L
Sbjct: 424 VMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQS 483
Query: 301 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 360
V+VFV A L +LI I+V+ +H +R Q+ R+ + +F+ GK+ +LI
Sbjct: 484 MSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIA 543
Query: 361 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 420
T L +RG+D V V N+DFP + EY+HRIGRTGRAG G +IT T +D + +
Sbjct: 544 TDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELI 603
Query: 421 NVIQQAGCPVPEYIKGF-QKLLSKQKKKMIKKPLER 455
N++++A +PE + ++ + Q+K+ +++ +ER
Sbjct: 604 NILERANQSIPEELVSMAERFKAHQQKREMERKMER 639
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 206 bits (524), Expect = 4e-53
Identities = 141/440 (32%), Positives = 232/440 (52%), Gaps = 34/440 (7%)
Query: 16 ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 75
E +L SG + EK + + + G++ P I F +D + ++ NI
Sbjct: 145 EQELFSGGNTGINFEKYDDI----PVEATGSNCPPHIENFSDID----MGEIIMGNIELT 196
Query: 76 GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 123
+ PTP+Q AIP++ R+L+A A TGSGKT AF +PIL Q+ K+
Sbjct: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256
Query: 124 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 178
G R +L+++PTRELA QI+ E K S + R +++ A ++ +
Sbjct: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 315
Query: 179 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 238
+LV TP RL+ ++++ G+D ++LV+DE+D++ + GF Q+ I T
Sbjct: 316 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 370
Query: 239 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 295
VR M FSATF +++ + LD I +++G S E + Q++++V + +
Sbjct: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430
Query: 296 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 355
L G + LVFV++ + A L L +EG IH +R+Q+ R+ +H FR+GK
Sbjct: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490
Query: 356 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 415
+L+ TA+ ARG+D V VIN+D P+ EY+HRIGRTGR GN G A +FF E + +
Sbjct: 491 PILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNI 550
Query: 416 LRSVANVIQQAGCPVPEYIK 435
+ + +++ +A VP +++
Sbjct: 551 TKDLLDLLVEAKQEVPSWLE 570
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 206 bits (524), Expect = 4e-53
Identities = 141/440 (32%), Positives = 232/440 (52%), Gaps = 34/440 (7%)
Query: 16 ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 75
E +L SG + EK + + + G++ P I F +D + ++ NI
Sbjct: 145 EQELFSGGNTGINFEKYDDI----PVEATGSNCPPHIENFSDID----MGEIIMGNIELT 196
Query: 76 GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 123
+ PTP+Q AIP++ R+L+A A TGSGKT AF +PIL Q+ K+
Sbjct: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256
Query: 124 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 178
G R +L+++PTRELA QI+ E K S + R +++ A ++ +
Sbjct: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 315
Query: 179 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 238
+LV TP RL+ ++++ G+D ++LV+DE+D++ + GF Q+ I T
Sbjct: 316 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 370
Query: 239 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 295
VR M FSATF +++ + LD I +++G S E + Q++++V + +
Sbjct: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430
Query: 296 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 355
L G + LVFV++ + A L L +EG IH +R+Q+ R+ +H FR+GK
Sbjct: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490
Query: 356 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 415
+L+ TA+ ARG+D V VIN+D P+ EY+HRIGRTGR GN G A +FF E + +
Sbjct: 491 PILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNI 550
Query: 416 LRSVANVIQQAGCPVPEYIK 435
+ + +++ +A VP +++
Sbjct: 551 TKDLLDLLVEAKQEVPSWLE 570
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 206 bits (523), Expect = 5e-53
Identities = 137/405 (33%), Positives = 223/405 (55%), Gaps = 18/405 (4%)
Query: 41 IHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLAS 100
+ V G D P I TF++ + +N+ NI AG+ TP+Q +IP++L GR+L+A
Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNN----NIAKAGYTKLTPVQKYSIPIILAGRDLMAC 331
Query: 101 APTGSGKTLAFSIPILMQLKQPANKGFR--------ALIISPTRELASQIHRELIKISEG 152
A TGSGKT AF +PIL + R +I++PTREL +QI+ E K S G
Sbjct: 332 AQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFG 391
Query: 153 TGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDES 212
T R +I+ + + +IL TP RL+ ++ ++ G L +++LV+DE+
Sbjct: 392 TCVRAVVIYGGTQLGHSIR-QIVQGCNILCATPGRLMDIIGKEKIG--LKQIKYLVLDEA 448
Query: 213 DKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNL-DNVISVSIGAR 271
D++ + G +L S + + + MFSATF ++++ L N + V++G
Sbjct: 449 DRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQV 508
Query: 272 NSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINV 331
A V+Q +L VG + K + E+++ + +VFV++ ++A + L E I+
Sbjct: 509 GGACRDVQQTVLQVG-QFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKIST 567
Query: 332 DVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHR 391
IH +R Q++R+ + FR GK VL+ T++ ARG+D + V VIN+D P++ EY+HR
Sbjct: 568 TSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHR 627
Query: 392 IGRTGRAGNKGKAITFF-TEDDKPLLRSVANVIQQAGCPVPEYIK 435
IGRTGR GN G+AI+FF E D L + + V+ A VP +++
Sbjct: 628 IGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLE 672
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 206 bits (523), Expect = 5e-53
Identities = 137/405 (33%), Positives = 223/405 (55%), Gaps = 18/405 (4%)
Query: 41 IHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLAS 100
+ V G D P I TF++ + +N+ NI AG+ TP+Q +IP++L GR+L+A
Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNN----NIAKAGYTKLTPVQKYSIPIILAGRDLMAC 331
Query: 101 APTGSGKTLAFSIPILMQLKQPANKGFR--------ALIISPTRELASQIHRELIKISEG 152
A TGSGKT AF +PIL + R +I++PTREL +QI+ E K S G
Sbjct: 332 AQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFG 391
Query: 153 TGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDES 212
T R +I+ + + +IL TP RL+ ++ ++ G L +++LV+DE+
Sbjct: 392 TCVRAVVIYGGTQLGHSIR-QIVQGCNILCATPGRLMDIIGKEKIG--LKQIKYLVLDEA 448
Query: 213 DKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNL-DNVISVSIGAR 271
D++ + G +L S + + + MFSATF ++++ L N + V++G
Sbjct: 449 DRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQV 508
Query: 272 NSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINV 331
A V+Q +L VG + K + E+++ + +VFV++ ++A + L E I+
Sbjct: 509 GGACRDVQQTVLQVG-QFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKIST 567
Query: 332 DVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHR 391
IH +R Q++R+ + FR GK VL+ T++ ARG+D + V VIN+D P++ EY+HR
Sbjct: 568 TSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHR 627
Query: 392 IGRTGRAGNKGKAITFF-TEDDKPLLRSVANVIQQAGCPVPEYIK 435
IGRTGR GN G+AI+FF E D L + + V+ A VP +++
Sbjct: 628 IGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLE 672
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 206 bits (523), Expect = 5e-53
Identities = 137/405 (33%), Positives = 223/405 (55%), Gaps = 18/405 (4%)
Query: 41 IHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLAS 100
+ V G D P I TF++ + +N+ NI AG+ TP+Q +IP++L GR+L+A
Sbjct: 242 VEVSGHDAPPAILTFEEANLCQTLNN----NIAKAGYTKLTPVQKYSIPIILAGRDLMAC 297
Query: 101 APTGSGKTLAFSIPILMQLKQPANKGFR--------ALIISPTRELASQIHRELIKISEG 152
A TGSGKT AF +PIL + R +I++PTREL +QI+ E K S G
Sbjct: 298 AQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFG 357
Query: 153 TGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDES 212
T R +I+ + + +IL TP RL+ ++ ++ G L +++LV+DE+
Sbjct: 358 TCVRAVVIYGGTQLGHSIR-QIVQGCNILCATPGRLMDIIGKEKIG--LKQIKYLVLDEA 414
Query: 213 DKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNL-DNVISVSIGAR 271
D++ + G +L S + + + MFSATF ++++ L N + V++G
Sbjct: 415 DRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQV 474
Query: 272 NSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINV 331
A V+Q +L VG + K + E+++ + +VFV++ ++A + L E I+
Sbjct: 475 GGACRDVQQTVLQVG-QFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKIST 533
Query: 332 DVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHR 391
IH +R Q++R+ + FR GK VL+ T++ ARG+D + V VIN+D P++ EY+HR
Sbjct: 534 TSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHR 593
Query: 392 IGRTGRAGNKGKAITFF-TEDDKPLLRSVANVIQQAGCPVPEYIK 435
IGRTGR GN G+AI+FF E D L + + V+ A VP +++
Sbjct: 594 IGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLE 638
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 204 bits (520), Expect = 1e-52
Identities = 140/440 (31%), Positives = 232/440 (52%), Gaps = 34/440 (7%)
Query: 16 ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 75
E +L SG + EK + + + G + P I +F ++ + ++ NI
Sbjct: 147 EQELFSGGNTGINFEKYDDI----PVEATGNNCPPHIESFSDVE----MGEIIMGNIELT 198
Query: 76 GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 123
+ PTP+Q AIP++ R+L+A A TGSGKT AF +PIL Q+ K+
Sbjct: 199 RYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENG 258
Query: 124 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 178
G R +L+++PTRELA QI+ E K S + R +++ A ++ +
Sbjct: 259 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 317
Query: 179 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 238
+LV TP RL+ ++++ G+D ++LV+DE+D++ + GF Q+ I T
Sbjct: 318 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 372
Query: 239 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 295
VR M FSATF +++ + LD I +++G S E + Q++++V + +
Sbjct: 373 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLL 432
Query: 296 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 355
L G + LVFV++ + A L L +EG IH +R+Q+ R+ +H FR+GK
Sbjct: 433 DLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 492
Query: 356 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 415
+L+ TA+ ARG+D V VIN+D P+ EY+HRIGRTGR GN G A +FF E + +
Sbjct: 493 PILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINI 552
Query: 416 LRSVANVIQQAGCPVPEYIK 435
+ + +++ +A VP +++
Sbjct: 553 TKDLLDLLVEAKQEVPSWLE 572
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 200 bits (509), Expect = 2e-51
Identities = 139/459 (30%), Positives = 233/459 (50%), Gaps = 47/459 (10%)
Query: 7 KIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINS 66
K E K+ + + KL+ + R + I +G +P+PI +++ + +
Sbjct: 345 KKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWK----DSSLPP 400
Query: 67 RLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK------ 120
+L+ I G++ PTPIQ QAIP+ L R+++ A TGSGKT AF IP+L+ +
Sbjct: 401 HILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKID 460
Query: 121 --QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 178
+ +++G A+I++PTRELA QI E IK + G R + ++ + G +
Sbjct: 461 RIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVI-GGISREDQGFRLRMGC 519
Query: 179 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIF------- 231
+I++ TP RLI +L+ + L+ ++V+DE+D++ + GF + I
Sbjct: 520 EIVIATPGRLIDVLENRY--LVLSRCTYVVLDEADRMID---MGFEPDVQKILEHMPVSN 574
Query: 232 -----------------LACTSHKVRRA-MFSATFAYDVEQWCKLNLDNVISVSIGARNS 273
HK R+ MF+AT VE+ + L V IG+
Sbjct: 575 QKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGK 634
Query: 274 AVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDV 333
E VEQ++ F+ SE+ K + ++++GF+PP+++FV + L L G N
Sbjct: 635 PHERVEQKV-FLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACT 693
Query: 334 IHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIG 393
+H + Q+QR+ + + +AG +L+ T + RGID + V++V+NYD + +YIHRIG
Sbjct: 694 LHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIG 753
Query: 394 RTGRAGNKGKAITFFTEDDKPLLRSVANVIQQ---AGCP 429
RTGRAG G AITF T++D + + I + + CP
Sbjct: 754 RTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCP 792
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 196 bits (499), Expect = 3e-50
Identities = 129/423 (30%), Positives = 223/423 (52%), Gaps = 25/423 (5%)
Query: 26 NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQM 85
++ +E+ +R K+ I V+G +P PI +F+++ K + +L+ + G PTPIQ+
Sbjct: 154 SMSEERHERVRKKYHILVEGDGIPPPIKSFKEM----KFPAAILRGLKKKGIHHPTPIQI 209
Query: 86 QAIPVMLHGRELLASAPTGSGKTLAFSIPILM-------QLKQPANKGFRALIISPTREL 138
Q IP +L GR+++ A TGSGKTL F++P++M +L +G LII P+REL
Sbjct: 210 QGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSREL 269
Query: 139 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKK-----FDILVTTPNRLIYLLK 193
A Q H L + + A+ K + ++V TP RL+ LL+
Sbjct: 270 ARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQ 329
Query: 194 QDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVE 253
+ +D+ +L +DE+D++ + GF + +IF + + +FSAT ++
Sbjct: 330 KKMVSLDIC--RYLALDEADRMID---MGFEGDIRTIFSYFKGQR-QTLLFSATMPKKIQ 383
Query: 254 QWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQS 313
+ K L +++++G +A V QE+ +V E K++ + E ++K PPVL+F +
Sbjct: 384 NFAKSALVKPVTINVGRAGAASLDVIQEVEYV-KEEAKMVYLLECLQKT-PPPVLIFAEK 441
Query: 314 IERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGV 373
+ L+ +G+ IH + Q++R + +FR GK VL+ T + ++G+DF +
Sbjct: 442 KADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAI 501
Query: 374 NLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED-DKPLLRSVANVIQQAGCPVPE 432
VINYD P Y+HRIGRTGR+GN G A TF + D+ +L + ++ +A VP
Sbjct: 502 QHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPP 561
Query: 433 YIK 435
++
Sbjct: 562 VLQ 564
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 189 bits (481), Expect = 4e-48
Identities = 128/436 (29%), Positives = 225/436 (51%), Gaps = 38/436 (8%)
Query: 60 QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL 119
Q+ ++ LL+ I GF+ PTPIQ IPV L G+++ A A TG+GKT AF++P+L +L
Sbjct: 221 QDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERL 280
Query: 120 KQPANKG--FRALIISPTRELASQIHRELIKISEGTGFRIHMIH-----KAAVAAKKFGP 172
+ R L++ PTREL Q+H ++++ + K+ AA + P
Sbjct: 281 IYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAP 340
Query: 173 KSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFL 232
DIL+ TP RLI L + P L+S+E L++DE+D++ ++ F +Q+ I
Sbjct: 341 ------DILIATPGRLIDHL-HNCPSFHLSSIEVLILDEADRMLDEY---FEEQMKEIIR 390
Query: 233 ACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFV--GSETG 290
C+ H+ + +FSAT +V+ ++L N + + + + + QE + + E
Sbjct: 391 MCSHHR-QTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGD 449
Query: 291 KLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSF 350
+ + L+ + F V++F Q+ ++A + L G+ V +H +Q QR + F
Sbjct: 450 REAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRF 509
Query: 351 RAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTE 410
+ +I +L+ T + ARG+D +GV VIN+ P + Y+HR+GRT RAG G++++ E
Sbjct: 510 KDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGE 569
Query: 411 DDKPLLRSVANVIQQAGCPV------PEYIKGFQKLLSKQKKKMI---------KKPLER 455
D++ +L+ +++ A PV + I F+ + K +K + K+ +
Sbjct: 570 DERKMLK---EIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQS 626
Query: 456 ESISTTPKCFLEKAKD 471
E+ T K LEK K+
Sbjct: 627 EAQINTAKRLLEKGKE 642
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 184 bits (467), Expect = 2e-46
Identities = 139/451 (30%), Positives = 223/451 (49%), Gaps = 40/451 (8%)
Query: 16 ESKLTSGKLE----NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQN 71
ESK TS E N RKE N + K + +P P F+ Q+Y LL++
Sbjct: 181 ESKATSCMSEMQVINWRKENFNITCDDLKSGEKRL-IPKPTCRFKDAFQQYP---DLLKS 236
Query: 72 ILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL-KQPANKGFR-- 128
I+ G PTPIQ QA P++L G +L+ A TG+GKTL++ +P + L QP ++ R
Sbjct: 237 IIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISREQRNG 296
Query: 129 --ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKS--------SKKF 178
L+++PTRELA + E K S +K + +G ++ SK
Sbjct: 297 PGMLVLTPTRELALHVEAECSKYS----------YKGLKSICIYGGRNRNGQIEDISKGV 346
Query: 179 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 238
DI++ TP RL L + ++L S+ +LV+DE+DK+ + F Q+ I L +
Sbjct: 347 DIIIATPGRLNDLQMNN--SVNLRSITYLVIDEADKMLD---MEFEPQIRKILLDVRPDR 401
Query: 239 VRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNS-AVETVEQELLFVGSETGKLLAMRE 297
+ M SAT+ V Q L + + V +G N AV TV+Q ++ + + L
Sbjct: 402 -QTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEF 460
Query: 298 LVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWV 357
+ N V++FV A +L + +GI+ + +H Q ++ V F++G I +
Sbjct: 461 VENMSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKI 520
Query: 358 LICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLR 417
LI T +++RG+D V V NYDFP + Y+HR+G GR G G ++T T+ D +
Sbjct: 521 LITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAG 580
Query: 418 SVANVIQQAGCPVPE--YIKGFQKLLSKQKK 446
+ ++ +A VPE + Q L++QK+
Sbjct: 581 ELIKILDRANQSVPEDLVVMAEQYKLNQQKR 611
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 183 bits (464), Expect = 4e-46
Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%)
Query: 23 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 82
++ NL +++ LR+K + V G P P ++F + + +L+ I + + PTP
Sbjct: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278
Query: 83 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 138
IQ Q +PV L GR+++ A TGSGKT AF P+L+ Q + G A+I+ PTREL
Sbjct: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338
Query: 139 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 198
QIH E + + R ++ ++ + +I+V TP RLI +K+
Sbjct: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395
Query: 199 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 258
+L V +LV DE+D++F+ GF Q+ SI + + +FSATF +E+ +
Sbjct: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451
Query: 259 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 316
L + I V G A E V Q E+L G L R LV+ + VL+FV
Sbjct: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510
Query: 317 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 376
A+EL + L EG N+ ++H + Q +R+ + F+ I VL+ T + ARG+D + V
Sbjct: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570
Query: 377 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 412
INYD + HRIGRTGRAG KG A T T D
Sbjct: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 183 bits (464), Expect = 4e-46
Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%)
Query: 23 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 82
++ NL +++ LR+K + V G P P ++F + + +L+ I + + PTP
Sbjct: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278
Query: 83 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 138
IQ Q +PV L GR+++ A TGSGKT AF P+L+ Q + G A+I+ PTREL
Sbjct: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338
Query: 139 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 198
QIH E + + R ++ ++ + +I+V TP RLI +K+
Sbjct: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395
Query: 199 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 258
+L V +LV DE+D++F+ GF Q+ SI + + +FSATF +E+ +
Sbjct: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451
Query: 259 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 316
L + I V G A E V Q E+L G L R LV+ + VL+FV
Sbjct: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510
Query: 317 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 376
A+EL + L EG N+ ++H + Q +R+ + F+ I VL+ T + ARG+D + V
Sbjct: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570
Query: 377 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 412
INYD + HRIGRTGRAG KG A T T D
Sbjct: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 182 bits (463), Expect = 5e-46
Identities = 125/425 (29%), Positives = 221/425 (52%), Gaps = 23/425 (5%)
Query: 12 KVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDL-PDPIATFQQLDQEYKINSRLLQ 70
K ++ + ++ L +++ LR K +I V+G D+ P P+ F + ++
Sbjct: 129 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHAN----FPQYVMD 184
Query: 71 NILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK-QP---ANKG 126
++D F PTPIQ Q P+ L GR+++ A TGSGKTLA+ +P ++ + QP G
Sbjct: 185 VLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDG 244
Query: 127 FRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPN 186
L+++PTRELA Q+ + + + + I+ A + + +I + TP
Sbjct: 245 PICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE-RGVEICIATPG 303
Query: 187 RLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSA 246
RLI L+ +L +LV+DE+D++ + GF Q+ I + + M+SA
Sbjct: 304 RLIDFLESGKT--NLRRCTYLVLDEADRMLD---MGFEPQIRKIVDQIRPDR-QTLMWSA 357
Query: 247 TFAYDVEQWCKLNLDNVISVSIG-----ARNSAVETVEQELLFVGSETGKLLAMRELVKK 301
T+ +V Q + L + +++G A ++ ++ V+ + + KL+ + E +
Sbjct: 358 TWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVD--VCMESEKDHKLIQLMEEIMA 415
Query: 302 GFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICT 361
++FV++ R +L + +G IH +++Q +RD ++ FR+GK +LI T
Sbjct: 416 EKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIAT 475
Query: 362 ALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVAN 421
+ +RG+D + V VINYD+P SS +Y+HRIGRT R+ NKG A TFFT + R +
Sbjct: 476 DVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIK 535
Query: 422 VIQQA 426
V+++A
Sbjct: 536 VLEEA 540
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 182 bits (463), Expect = 5e-46
Identities = 125/425 (29%), Positives = 221/425 (52%), Gaps = 23/425 (5%)
Query: 12 KVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDL-PDPIATFQQLDQEYKINSRLLQ 70
K ++ + ++ L +++ LR K +I V+G D+ P P+ F + ++
Sbjct: 129 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHAN----FPQYVMD 184
Query: 71 NILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK-QP---ANKG 126
++D F PTPIQ Q P+ L GR+++ A TGSGKTLA+ +P ++ + QP G
Sbjct: 185 VLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDG 244
Query: 127 FRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPN 186
L+++PTRELA Q+ + + + + I+ A + + +I + TP
Sbjct: 245 PICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE-RGVEICIATPG 303
Query: 187 RLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSA 246
RLI L+ +L +LV+DE+D++ + GF Q+ I + + M+SA
Sbjct: 304 RLIDFLESGKT--NLRRCTYLVLDEADRMLD---MGFEPQIRKIVDQIRPDR-QTLMWSA 357
Query: 247 TFAYDVEQWCKLNLDNVISVSIG-----ARNSAVETVEQELLFVGSETGKLLAMRELVKK 301
T+ +V Q + L + +++G A ++ ++ V+ + + KL+ + E +
Sbjct: 358 TWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVD--VCMESEKDHKLIQLMEEIMA 415
Query: 302 GFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICT 361
++FV++ R +L + +G IH +++Q +RD ++ FR+GK +LI T
Sbjct: 416 EKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIAT 475
Query: 362 ALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVAN 421
+ +RG+D + V VINYD+P SS +Y+HRIGRT R+ NKG A TFFT + R +
Sbjct: 476 DVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIK 535
Query: 422 VIQQA 426
V+++A
Sbjct: 536 VLEEA 540
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 181 bits (460), Expect = 1e-45
Identities = 119/362 (32%), Positives = 192/362 (53%), Gaps = 13/362 (3%)
Query: 61 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 120
+ + LL+ I GF+ P+ IQ +AI + G +++A A +G+GKT F+I IL QL+
Sbjct: 37 DMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLE 96
Query: 121 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 180
K +AL+++PTRELA QI + ++ + + G H + ++ I
Sbjct: 97 IEF-KETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHI 155
Query: 181 LVTTPNRLIYLLKQDPPGIDLASVEWL---VVDESDKLFEDGKTGFRDQLASIFLACTSH 237
+V TP R+ +L + S +W+ V+DE+D++ GF+DQ+ IF +
Sbjct: 156 VVGTPGRVFDMLNRR-----YLSPKWIKMFVLDEADEMLS---RGFKDQIYEIFQKLNT- 206
Query: 238 KVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRE 297
++ + SAT DV + K + + I + + +E ++Q + V E KL + +
Sbjct: 207 SIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCD 266
Query: 298 LVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWV 357
L + ++F+ + + L ++ V +H + Q++RD + FR+G V
Sbjct: 267 LYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRV 326
Query: 358 LICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLR 417
LI T LLARGID + V+LVINYD PT+ YIHRIGR GR G KG AI F TE+DK +LR
Sbjct: 327 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386
Query: 418 SV 419
+
Sbjct: 387 DI 388
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 179 bits (455), Expect = 4e-45
Identities = 116/375 (30%), Positives = 199/375 (53%), Gaps = 9/375 (2%)
Query: 60 QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL 119
++Y + LL I + G++ P+PIQ ++IP+ L GR++LA A G+GK+ A+ IP+L +L
Sbjct: 99 EDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERL 158
Query: 120 KQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFD 179
+ +A++I PTRELA Q+ + I++S+ G M + +
Sbjct: 159 DLKKDN-IQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 217
Query: 180 ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKV 239
+++ TP R++ L+K+ +D V+ +V+DE+DKL F + I L ++
Sbjct: 218 VVIATPGRILDLIKKGVAKVD--HVQMIVLDEADKLLSQD---FVQIMEDIILTLPKNR- 271
Query: 240 RRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELV 299
+ ++SATF V+++ +L +++ ++ V Q +V +E K+ + L
Sbjct: 272 QILLYSATFPLSVQKFMNSHLQKPYEINL-MEELTLKGVTQYYAYV-TERQKVHCLNTLF 329
Query: 300 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 359
+ ++F S +R + L ++ G + IHA+ Q+ R+ H FR G L+
Sbjct: 330 SRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLV 389
Query: 360 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 419
CT L RGID + VN+VIN+DFP + Y+HRIGR+GR G+ G AI T DD+ L+S+
Sbjct: 390 CTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSI 449
Query: 420 ANVIQQAGCPVPEYI 434
+ P+P I
Sbjct: 450 EEQLGTEIKPIPSNI 464
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 177 bits (449), Expect = 2e-44
Identities = 116/359 (32%), Positives = 188/359 (52%), Gaps = 7/359 (1%)
Query: 61 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 120
+ ++ LL+ I GF+ P+ IQ +AI + G +++A A +G+GKT F+I IL Q++
Sbjct: 36 DMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIE 95
Query: 121 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 180
K +AL+++PTRELA QI + ++ + + G H + + I
Sbjct: 96 LDL-KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHI 154
Query: 181 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 240
+V TP R+ +L + + ++ V+DE+D++ GF+DQ+ IF S+ +
Sbjct: 155 IVGTPGRVFDMLNRRY--LSPKYIKMFVLDEADEMLS---RGFKDQIYDIFQKLNSN-TQ 208
Query: 241 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 300
+ SAT DV + K + + I + + +E + Q + V E KL + +L +
Sbjct: 209 VVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYE 268
Query: 301 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 360
++F+ + + L ++ V +H + Q++RD + FR+G VLI
Sbjct: 269 TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328
Query: 361 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 419
T LLARGID + V+LVINYD PT+ YIHRIGR GR G KG AI TE+DK LR +
Sbjct: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 175 bits (444), Expect = 7e-44
Identities = 116/387 (29%), Positives = 205/387 (52%), Gaps = 16/387 (4%)
Query: 42 HVQGTDLPDPIATFQQLD--QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLA 99
H T+ PI ++ ++ + L + G+ PT IQ++AIP+ L GR+++
Sbjct: 7 HDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIG 66
Query: 100 SAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHM 159
A TGSGKT AF++PIL L + + F AL+++PTRELA QI + + G + +
Sbjct: 67 LAETGSGKTGAFALPILNALLETPQRLF-ALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
Query: 160 IHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDG 219
I + + +KK I++ TP RLI L ++ G +L ++++LV+DE+D++
Sbjct: 126 I-VGGIDSMSQSLALAKKPHIIIATPGRLIDHL-ENTKGFNLRALKYLVMDEADRILN-- 181
Query: 220 KTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVE 279
F ++ I + + +FSAT V++ + L N + ++ ++ VE ++
Sbjct: 182 -MDFETEVDKILKVIPRDR-KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQ 239
Query: 280 QELLFVGS---ETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHA 336
Q +F+ S +T + + EL F ++F + + L G +H
Sbjct: 240 QYYIFIPSKFKDTYLVYILNELAGNSF----MIFCSTCNNTQRTALLLRNLGFTAIPLHG 295
Query: 337 ERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTG 396
+ +Q +R +++ F+A +L+ T + +RG+D V++V+N+D PT S +YIHR+GRT
Sbjct: 296 QMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTA 355
Query: 397 RAGNKGKAITFFTEDDKPLLRSVANVI 423
RAG GKAITF T+ D L + + ++I
Sbjct: 356 RAGRSGKAITFVTQYDVELFQRIEHLI 382
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 172 bits (436), Expect = 6e-43
Identities = 123/404 (30%), Positives = 208/404 (51%), Gaps = 18/404 (4%)
Query: 30 EKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIP 89
+++ R +I V+G + P P+ F E + ++ I F PT IQ Q P
Sbjct: 71 QEVETYRRSKEITVRGHNCPKPVLNFY----EANFPANVMDVIARQNFTEPTAIQAQGWP 126
Query: 90 VMLHGRELLASAPTGSGKTLAFSIPILMQLK-QP---ANKGFRALIISPTRELASQIHRE 145
V L G +++ A TGSGKTL++ +P ++ + QP G L+++PTRELA Q+ +
Sbjct: 127 VALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQV 186
Query: 146 LIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVE 205
+ + I+ A + + +I + TP RLI L+ +L
Sbjct: 187 AAEYCRACRLKSTCIYGGAPKGPQIRDLE-RGVEICIATPGRLIDFLECGKT--NLRRTT 243
Query: 206 WLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVIS 265
+LV+DE+D++ + GF Q+ I + + M+SAT+ +V Q + L + I
Sbjct: 244 YLVLDEADRMLD---MGFEPQIRKIVDQIRPDR-QTLMWSATWPKEVRQLAEDFLKDYIH 299
Query: 266 VSIGARN-SAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFH 322
++IGA SA + Q ++ + KL+ + E + +VFV++ R EL
Sbjct: 300 INIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTR 359
Query: 323 ELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFP 382
++ +G IH +++QQ+RD ++ F+ GK +LI T + +RG+D + V VINYD+P
Sbjct: 360 KMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYP 419
Query: 383 TSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQA 426
SS +YIHRIGRT R+ G A TFFT ++ + + +V+++A
Sbjct: 420 NSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREA 463
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 165 bits (418), Expect = 8e-41
Identities = 127/400 (31%), Positives = 205/400 (51%), Gaps = 26/400 (6%)
Query: 64 INSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP---ILMQLK 120
+N L+ I + GF T IQ ++I +L GR+LLA+A TGSGKTLAF IP ++++L+
Sbjct: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 245
Query: 121 QPANKGFRALIISPTRELASQ---IHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKK 177
G LI+SPTRELA Q + +EL+ T I + A+K G
Sbjct: 246 FMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLG----NG 301
Query: 178 FDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSH 237
+I+V TP RL+ + Q+ PG +++ LV+DE+D++ + GF ++L I +
Sbjct: 302 INIIVATPGRLLDHM-QNTPGFMYKNLQCLVIDEADRILD---VGFEEELKQIIKLLPTR 357
Query: 238 KVRRAMFSATFAYDVEQWCKLNLDN---VISVSIGARNSAVETVEQELLFVGSETGKLLA 294
+ + +FSAT VE +++L + V N+ V+ +EQ + SE + L
Sbjct: 358 R-QTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEK-RFLL 415
Query: 295 MRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGK 354
+ +KK ++VF S K + L Y + V IH ++ Q +R T F
Sbjct: 416 LFTFLKKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNAD 475
Query: 355 IWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGN-KGKAITFFTEDDK 413
L+CT + ARG+D V+ ++ YD P EYIHR+GRT R N +G A+ ++
Sbjct: 476 SGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEEL 535
Query: 414 PLLRSVANVIQQAGCPVPEYIKGFQKL--LSKQKKKMIKK 451
LR ++Q+ P+ E+ + K+ + Q +K+I+K
Sbjct: 536 GFLR----YLKQSKVPLSEFDFSWSKISDIQSQLEKLIEK 571
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 163 bits (413), Expect = 3e-40
Identities = 116/365 (31%), Positives = 184/365 (50%), Gaps = 15/365 (4%)
Query: 55 FQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP 114
FQ + Y + + I+ G+++PTPIQ + IPV+L G++++A A TGSGKT F +P
Sbjct: 98 FQSMGLSYPV----FKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLP 153
Query: 115 ILMQLK-QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPK 173
+ +LK A G RALI+SPTRELA Q + ++ + TG + +I +F
Sbjct: 154 MFERLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAAL 213
Query: 174 SSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLA 233
DI++ TP RL+++ + + L SVE++V DE+D+LFE GF +QL I +A
Sbjct: 214 HENP-DIIIATPGRLVHVAVE--MSLKLQSVEYVVFDEADRLFE---MGFAEQLQEI-IA 266
Query: 234 CTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLL 293
+ +FSAT + ++ + L + + + E ++ V +T K
Sbjct: 267 RLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDT-KAA 325
Query: 294 AMRELVKKGFNPP--VLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFR 351
+ L+ P +VFV + A+ L L + ++ I++ R + F
Sbjct: 326 VLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFT 385
Query: 352 AGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED 411
GK LI T L ARG+D ++ VINY FP ++HR+GR RAG G A + D
Sbjct: 386 LGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPD 445
Query: 412 DKPLL 416
+ P L
Sbjct: 446 EIPYL 450
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 163 bits (413), Expect = 3e-40
Identities = 116/365 (31%), Positives = 184/365 (50%), Gaps = 15/365 (4%)
Query: 55 FQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP 114
FQ + Y + + I+ G+++PTPIQ + IPV+L G++++A A TGSGKT F +P
Sbjct: 98 FQSMGLSYPV----FKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLP 153
Query: 115 ILMQLK-QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPK 173
+ +LK A G RALI+SPTRELA Q + ++ + TG + +I +F
Sbjct: 154 MFERLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAAL 213
Query: 174 SSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLA 233
DI++ TP RL+++ + + L SVE++V DE+D+LFE GF +QL I +A
Sbjct: 214 HENP-DIIIATPGRLVHVAVE--MSLKLQSVEYVVFDEADRLFE---MGFAEQLQEI-IA 266
Query: 234 CTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLL 293
+ +FSAT + ++ + L + + + E ++ V +T K
Sbjct: 267 RLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDT-KAA 325
Query: 294 AMRELVKKGFNPP--VLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFR 351
+ L+ P +VFV + A+ L L + ++ I++ R + F
Sbjct: 326 VLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFT 385
Query: 352 AGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED 411
GK LI T L ARG+D ++ VINY FP ++HR+GR RAG G A + D
Sbjct: 386 LGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPD 445
Query: 412 DKPLL 416
+ P L
Sbjct: 446 EIPYL 450
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 159 bits (403), Expect = 4e-39
Identities = 126/467 (26%), Positives = 225/467 (48%), Gaps = 33/467 (7%)
Query: 9 EDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRL 68
++KK Q +L + + R+ ++N KI+V + I F ++ ++ +
Sbjct: 31 QNKKKQLRKQLKKPEWQVERESISRLMQNYEKINV------NEITRFS----DFPLSKKT 80
Query: 69 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPIL---MQLKQPANK 125
L+ + +A +++ T IQ Q I + L G+++L +A TGSGKTLAF +P+L +L+ +
Sbjct: 81 LKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTD 140
Query: 126 GFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSK--KFDILVT 183
G LIISPTRELA Q L K+ + F +I + K ++ + +ILV
Sbjct: 141 GLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLI----IGGKDLKHEAERINNINILVC 196
Query: 184 TPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAM 243
TP RL+ + + ++ LV+DE+D++ + GF D + ++ + K + +
Sbjct: 197 TPGRLLQHM-DETVSFHATDLQMLVLDEADRILD---MGFADTMNAV-IENLPKKRQTLL 251
Query: 244 FSATFAYDVEQWCKLNLDN--VISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKK 301
FSAT V+ +L+L N + V A+ S T+EQ + + K+ + ++
Sbjct: 252 FSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQ-KISVLYSFLRS 310
Query: 302 GFNPPVLVFVQSIERAKELFHEL--IYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 359
+VF S + + L+ + G+++ +H + Q +R + F + VL
Sbjct: 311 HLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAVLF 370
Query: 360 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 419
T + ARG+DF VN V+ +D P + YIHR GRT R G+A+ +K +++
Sbjct: 371 ATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEKAMVQQ- 429
Query: 420 ANVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFL 466
+ Q PV E +KL+ QKK +++ +CF+
Sbjct: 430 ---LLQKKVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFV 473
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 157 bits (396), Expect = 3e-38
Identities = 107/384 (27%), Positives = 196/384 (51%), Gaps = 20/384 (5%)
Query: 40 KIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLA 99
K+ + ++ D TF + + LL+ I GF+ P+ IQ +AI ++ GR+++A
Sbjct: 25 KVEFETSEEVDVTPTFDTMG----LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIA 80
Query: 100 SAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHM 159
+ +G+GKT FSI +L L + +ALI++PTRELA QI + L+ + + + H
Sbjct: 81 QSQSGTGKTATFSISVLQCLDIQVRET-QALILAPTRELAVQIQKGLLALGDYMNVQCH- 138
Query: 160 IHKAAVAAKKFGPKSSKKFD----ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKL 215
A + G + +K D ++ TP R+ ++++ + +++ LV+DE+D++
Sbjct: 139 ---ACIGGTNVG-EDIRKLDYGQHVVAGTPGRVFDMIRRR--SLRTRAIKMLVLDEADEM 192
Query: 216 FEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAV 275
G F++Q+ ++ + + SAT +++ + + + I + + +
Sbjct: 193 LNKG---FKEQIYDVYRYLPP-ATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTL 248
Query: 276 ETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIH 335
E ++Q + V E K + +L ++F + + L ++ V +H
Sbjct: 249 EGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMH 308
Query: 336 AERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRT 395
+ Q++R++ + FR+G VLI T + ARG+D V+L+INYD P + YIHRIGR+
Sbjct: 309 GDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRS 368
Query: 396 GRAGNKGKAITFFTEDDKPLLRSV 419
GR G KG AI F DD +LR +
Sbjct: 369 GRYGRKGVAINFVKNDDIRILRDI 392
>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
sapiens]
Length = 427
Score = 156 bits (395), Expect = 4e-38
Identities = 110/377 (29%), Positives = 187/377 (49%), Gaps = 8/377 (2%)
Query: 60 QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL 119
+++ + LL+ I+D GF+ P+ +Q + IP + G ++L A +G GKT F + L Q+
Sbjct: 47 RDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQI 106
Query: 120 KQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFD 179
+P N L++ TRELA QI +E + S+ + ++ KK K
Sbjct: 107 -EPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCP 165
Query: 180 -ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 238
++V TP R++ L++ L +V+ V+DE DK+ E + R + IF T H+
Sbjct: 166 HVVVGTPGRILALVRNR--SFSLKNVKHFVLDECDKMLE--QLDMRRDVQEIF-RLTPHE 220
Query: 239 VRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMREL 298
+ MFSAT + D+ C+ + + + V + Q+ ++ K + +L
Sbjct: 221 KQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDL 280
Query: 299 VKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVL 358
+ V++FV+S++R L L+ + IH Q++R + F+ + +L
Sbjct: 281 LDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRIL 340
Query: 359 ICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFT-EDDKPLLR 417
+ T L RG+D + VN+V NYD P S Y+HR+ R GR G KG AITF + E+D +L
Sbjct: 341 VATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILN 400
Query: 418 SVANVIQQAGCPVPEYI 434
V + + +PE I
Sbjct: 401 DVQDRFEVNVAELPEEI 417
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,628,593
Number of Sequences: 37866
Number of extensions: 782956
Number of successful extensions: 2433
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2173
Number of HSP's gapped (non-prelim): 117
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.