Guide to the Human Genome
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Search of human proteins with 38569411

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38569411 AP1 gamma subunit binding protein 1 isoform 2 [Homo
sapiens]
         (1302 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38569411 AP1 gamma subunit binding protein 1 isoform 2 [Homo ...  2581   0.0  
gi|38569409 AP1 gamma subunit binding protein 1 isoform 1 [Homo ...  2572   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    64   1e-09
gi|148612857 sickle tail isoform 3 [Homo sapiens]                      50   1e-05
gi|148612813 sickle tail isoform 2 [Homo sapiens]                      50   1e-05
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                       47   1e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        46   2e-04
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa...    46   3e-04
gi|91982772 mucin 17 [Homo sapiens]                                    46   3e-04
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                45   3e-04
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                45   3e-04
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa...    44   0.001
gi|110349786 Alstrom syndrome 1 [Homo sapiens]                         44   0.001
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    44   0.001
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    44   0.001
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    44   0.001
gi|45439359 triple functional domain (PTPRF interacting) [Homo s...    43   0.002
gi|4503593 epidermal growth factor receptor pathway substrate 15...    43   0.002
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    43   0.002
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    42   0.004
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    42   0.004

>gi|38569411 AP1 gamma subunit binding protein 1 isoform 2 [Homo
            sapiens]
          Length = 1302

 Score = 2581 bits (6690), Expect = 0.0
 Identities = 1302/1302 (100%), Positives = 1302/1302 (100%)

Query: 1    MALRPGAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVMQPNM 60
            MALRPGAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVMQPNM
Sbjct: 1    MALRPGAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVMQPNM 60

Query: 61   QGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFA 120
            QGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFA
Sbjct: 61   QGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFA 120

Query: 121  EEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFS 180
            EEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFS
Sbjct: 121  EEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFS 180

Query: 181  RDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGHKALGPGSSKKYPS 240
            RDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGHKALGPGSSKKYPS
Sbjct: 181  RDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGHKALGPGSSKKYPS 240

Query: 241  LMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQPRMPPWIYNESLVP 300
            LMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQPRMPPWIYNESLVP
Sbjct: 241  LMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQPRMPPWIYNESLVP 300

Query: 301  DAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLA 360
            DAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLA
Sbjct: 301  DAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLA 360

Query: 361  MIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAGSMPLSLGQP 420
            MIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAGSMPLSLGQP
Sbjct: 361  MIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAGSMPLSLGQP 420

Query: 421  VMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQEL 480
            VMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQEL
Sbjct: 421  VMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQEL 480

Query: 481  PASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENTVPPGDPGDKYS 540
            PASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENTVPPGDPGDKYS
Sbjct: 481  PASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENTVPPGDPGDKYS 540

Query: 541  AFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKDKTFPPSFPSGTI 600
            AFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKDKTFPPSFPSGTI
Sbjct: 541  AFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKDKTFPPSFPSGTI 600

Query: 601  QQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAA 660
            QQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAA
Sbjct: 601  QQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAA 660

Query: 661  TKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEAS 720
            TKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEAS
Sbjct: 661  TKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEAS 720

Query: 721  PVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFH 780
            PVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFH
Sbjct: 721  PVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFH 780

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
            SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL
Sbjct: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840

Query: 841  ADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRD 900
            ADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRD
Sbjct: 841  ADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRD 900

Query: 901  DATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKVTTFVSEDALPETT 960
            DATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKVTTFVSEDALPETT
Sbjct: 901  DATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKVTTFVSEDALPETT 960

Query: 961  FPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNEC 1020
            FPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNEC
Sbjct: 961  FPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNEC 1020

Query: 1021 SDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKE 1080
            SDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKE
Sbjct: 1021 SDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKE 1080

Query: 1081 ISRSSPSPALEQPFRDRSNTLNEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALN 1140
            ISRSSPSPALEQPFRDRSNTLNEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALN
Sbjct: 1081 ISRSSPSPALEQPFRDRSNTLNEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALN 1140

Query: 1141 VIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQ 1200
            VIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQ
Sbjct: 1141 VIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQ 1200

Query: 1201 LLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRA 1260
            LLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRA
Sbjct: 1201 LLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRA 1260

Query: 1261 FNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLVLPDLL 1302
            FNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLVLPDLL
Sbjct: 1261 FNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLVLPDLL 1302


>gi|38569409 AP1 gamma subunit binding protein 1 isoform 1 [Homo
            sapiens]
          Length = 1314

 Score = 2572 bits (6667), Expect = 0.0
 Identities = 1302/1314 (99%), Positives = 1302/1314 (99%), Gaps = 12/1314 (0%)

Query: 1    MALRPGAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVMQPNM 60
            MALRPGAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVMQPNM
Sbjct: 1    MALRPGAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVMQPNM 60

Query: 61   QGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFA 120
            QGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFA
Sbjct: 61   QGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFA 120

Query: 121  EEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFS 180
            EEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFS
Sbjct: 121  EEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFS 180

Query: 181  RDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGHKALGPGSSKKYPS 240
            RDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGHKALGPGSSKKYPS
Sbjct: 181  RDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGHKALGPGSSKKYPS 240

Query: 241  LMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQPRMPPWIYNESLVP 300
            LMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQPRMPPWIYNESLVP
Sbjct: 241  LMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQPRMPPWIYNESLVP 300

Query: 301  DAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLA 360
            DAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLA
Sbjct: 301  DAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLA 360

Query: 361  MIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAGSMPLSLGQP 420
            MIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAGSMPLSLGQP
Sbjct: 361  MIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAGSMPLSLGQP 420

Query: 421  VMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQEL 480
            VMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQEL
Sbjct: 421  VMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQEL 480

Query: 481  PASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENTVPPGDPGDKYS 540
            PASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENTVPPGDPGDKYS
Sbjct: 481  PASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENTVPPGDPGDKYS 540

Query: 541  AFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKDKTFPPSFPSGTI 600
            AFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKDKTFPPSFPSGTI
Sbjct: 541  AFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKDKTFPPSFPSGTI 600

Query: 601  QQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAA 660
            QQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAA
Sbjct: 601  QQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAA 660

Query: 661  TKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEAS 720
            TKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEAS
Sbjct: 661  TKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEAS 720

Query: 721  PVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFH 780
            PVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFH
Sbjct: 721  PVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFH 780

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
            SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL
Sbjct: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840

Query: 841  ADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRD 900
            ADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRD
Sbjct: 841  ADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRD 900

Query: 901  DATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKVTTFVSEDALPETT 960
            DATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKVTTFVSEDALPETT
Sbjct: 901  DATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKVTTFVSEDALPETT 960

Query: 961  FPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNEC 1020
            FPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNEC
Sbjct: 961  FPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNEC 1020

Query: 1021 SDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKE 1080
            SDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKE
Sbjct: 1021 SDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKE 1080

Query: 1081 ISRSSPSPALEQPFRDRSNTLNEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALN 1140
            ISRSSPSPALEQPFRDRSNTLNEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALN
Sbjct: 1081 ISRSSPSPALEQPFRDRSNTLNEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALN 1140

Query: 1141 VIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQ 1200
            VIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQ
Sbjct: 1141 VIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQ 1200

Query: 1201 LLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSR- 1259
            LLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSR 
Sbjct: 1201 LLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRK 1260

Query: 1260 -----------AFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLVLPDLL 1302
                       AFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLVLPDLL
Sbjct: 1261 EEKPAEEHPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLVLPDLL 1314


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 124/647 (19%), Positives = 226/647 (34%), Gaps = 26/647 (4%)

Query: 454  EEDDFQDFQDASKSGSLDDSFSDFQELPASSKTSNSQHGNSAPSLLMPLPGTKALPSMDK 513
            +  D  D  D+S S +  DS SD  +   SS +S+S + + +         +++  S D 
Sbjct: 649  DSSDNSDSSDSSNSSNSSDS-SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS 707

Query: 514  YAVFKGIAADKSSENTVPPGDPGDKYSAFRELEQTAENKPLGESFAEFRSAGTDDGFTDF 573
                   ++D S+ N+          S+  +   ++++    +S     S+ + D     
Sbjct: 708  SDSDSSDSSDSSNSNSSDSDSSNSSDSS--DSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765

Query: 574  KTADSVSPLEPPTKDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSF 633
             ++DS    +      +   +  S +      +   +  N +D    SS +  S+   S 
Sbjct: 766  DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD-SSDSSDSSDSDSSNSS 824

Query: 634  SAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYSGLAPVGEQDDFAD 693
             +  S+  S S+  S  S ++ ++  +   SS   D    S   + S  +   +  D +D
Sbjct: 825  DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884

Query: 694  FMAFSNSSISSE------------QKPDDKYDALKEEASPVPLTSNVGSTVKGGQNSTAA 741
                SNSS SS+                D  D+     S     S+  S      NS+ +
Sbjct: 885  SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944

Query: 742  STKYDVFRQLSLEGS--GLGVEDLKDNTPSGKSD-DDFADFHSSKFSSINSDKSLGEKAV 798
            S   D         S       D  D+  S  SD  + +D   S  SS +SD S    + 
Sbjct: 945  SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004

Query: 799  AFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDA-LSVQFDMKLADVGGDLKHVMSDSSLD 857
                + + S S  S D  +   SS   + S+ +  S   D   +    D  +    S   
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064

Query: 858  LPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGS 917
              + S     ++D  D   ++  S SSN + S+  S D SD  D++     S    S+ S
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSNS 1123

Query: 918  GSPSATSILQKKETSFGSSENITMTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQ 977
               S +S       S  SS++   +  S      S D+   +     +   D+   +   
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSD-----SSDSSDSSDSSDSSDSSDSSDSSDSS 1178

Query: 978  KEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNECSDDFGEFQSEKPKISKF 1037
               ++ D  D +     +       +  S  SS +S  + +  S D  +           
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238

Query: 1038 DFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKEISRS 1084
            D   ++  S    S +   S  +T D + +   +     G+   S S
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1285



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 125/623 (20%), Positives = 225/623 (36%), Gaps = 41/623 (6%)

Query: 465  SKSGSLDDSFSDFQELPASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADK 524
            SKS S D + SD  +   SS +SNS + + +         + +  S D        ++  
Sbjct: 638  SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS---------SDSSDSSDS-------SSSS 681

Query: 525  SSENTVPPGDPGDKYSAFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEP 584
             S N+    D  D          ++E+    +S     S  +D   ++   +DS +  + 
Sbjct: 682  DSSNSSDSSDSSDS-------SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734

Query: 585  PTKDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVS 644
                 +   S  S +      +   +  N +D    S  + SS+   S  +  S++ S S
Sbjct: 735  SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794

Query: 645  TPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISS 704
            +  S  S ++ ++ ++  + S   D    S   + S  +   +  + +D    S+SS  S
Sbjct: 795  SDSSNSSDSSNSSDSSDSSDSSDSDSSNSS---DSSNSSDSSDSSNSSDSSDSSDSSDGS 851

Query: 705  EQKPDDKYDALKEEASPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLK 764
            +    ++ D+     S     S+  S      +S  +S   D     S + S     D  
Sbjct: 852  DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD-----SSDSSNSSDSDSS 906

Query: 765  DNTPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVG 824
            D++ S  S D      SS+ SS +SD S    +     + + S S  S D  +   SS  
Sbjct: 907  DSSNSSDSSDSSNSSDSSE-SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965

Query: 825  KEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSS 884
             + S+   S   D   +    D     SDSS    + S     ++D  D   ++  S SS
Sbjct: 966  SDSSDSNSSDSSDSSNSSDSSDSSD-SSDSSDS--SDSSNSSDSSDSSDSSDSSNSSDSS 1022

Query: 885  NFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSL 944
            N + S+  S D SD  D++     S    S+ S + S +S       S  SS++   +  
Sbjct: 1023 NSSDSS-NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081

Query: 945  SKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATC 1004
            S+     S D+   +     +   D+   +      ++ D  D +     +       + 
Sbjct: 1082 SE-----SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136

Query: 1005 PSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDL 1064
             S  SS +S  + +  S D  +           D   ++  S    S +   S  ++   
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196

Query: 1065 SVQGSHKRSLSLGDKEISRSSPS 1087
                S   S S    + S SS S
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDS 1219



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 126/629 (20%), Positives = 233/629 (37%), Gaps = 22/629 (3%)

Query: 463  DASKSGSLDDSFSDFQELPASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAA 522
            D+S S S  DS S   +   SS + +S   NS+ S       + +  S D        ++
Sbjct: 570  DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS----SDSSDSSDSSD-----SSDSS 620

Query: 523  DKSSENTVPPGDPGDKYSAFRELE-QTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSP 581
            D  S+++    D  D  S     +  ++++    +S     S+ + D      ++DS S 
Sbjct: 621  DSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680

Query: 582  LEPPTKDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSK 641
             +      +   S  S + +    +   +  +    D  +S +  S+   S  +  S++ 
Sbjct: 681  SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740

Query: 642  SVSTPQSTGSAATMTALAA-TKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNS 700
            S S+  S  S ++ ++ ++ +  SS + D  + S   + S  +   +  + +D    SNS
Sbjct: 741  SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800

Query: 701  SISSEQK-PDDKYDALKEEASPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLG 759
            S SS      D  D+   ++S    +SN  S      NS+ +S   D     S +GS   
Sbjct: 801  SDSSNSSDSSDSSDSSDSDSSNSSDSSN-SSDSSDSSNSSDSSDSSD-----SSDGSDSD 854

Query: 760  VEDLKDNTPSGKSDDDFADFHSSKFS-SINSDKSLGEKAVAFRHTKEDSASVKSLDLPSI 818
              +  D++ S  S D     +SS  S S +S++S      +      DS S  S +    
Sbjct: 855  SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914

Query: 819  GGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAA 878
              SS   + SE + S                  SDSS    + +      +       ++
Sbjct: 915  SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974

Query: 879  FGSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSEN 938
              S SSN + S+  S D SD  D++     S    S+ S   S +S       S  SS++
Sbjct: 975  DSSDSSNSSDSS-DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033

Query: 939  ITMTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAER 998
               +  S  +   S D+   +     +   D+   +      ++ D  D ++    +   
Sbjct: 1034 SDSSDSSDSSD--SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091

Query: 999  SQEATCPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            +   +  S  SS +S  + +  S D  +  +        D   ++  S    S +  +S 
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSSPS 1087
             ++       S   S S    + S SS S
Sbjct: 1152 DSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 106/506 (20%), Positives = 183/506 (36%), Gaps = 13/506 (2%)

Query: 447  ANQVVKPEEDDFQDFQDASKSGSLDDS--FSDFQELPASSKTSNSQHGNSAPSLLMPLPG 504
            +N     +  D  D  D+S S   +DS   SD  +   SS +SNS   + +         
Sbjct: 762  SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821

Query: 505  TKALPSMDKYAVFKGIAADKSSENTVPPGDPGDKYSAFRELEQTAENKPLGESFAEFRSA 564
              +  S    +     ++D S  +    G   D  S   +   ++++    +S     S+
Sbjct: 822  NSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS-SNRSDSSNSSDSSDSSDSSNSSDSS 880

Query: 565  GTDDGFTDFKTADS-----VSPLEPPTKDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDM 619
             + D      ++DS      S  +      +   S  S +    + +   +  N +D   
Sbjct: 881  DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940

Query: 620  FSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEY 679
             S  + SS+   S  +  S+  S S+  S  +++  +  + +  SS + D  + S   + 
Sbjct: 941  SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000

Query: 680  SGLAPVGEQDDFADFMAFSNSSISSE-QKPDDKYDALKEEASPVPLTSNVGSTVKGGQNS 738
            S  +   +  D +D    S+SS SS+     D  D+     S     S+  S      +S
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060

Query: 739  TAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSD-DDFADFHSSKFSSINSDKSLGEKA 797
            + +S   D         S    E    +  S  SD  D +D   S  SS +SD S    +
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120

Query: 798  VAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLD 857
                 + + S S  S D  +   SS   E S+   S   D   +    D       S   
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS--SDSSDSSDSSDSSDSSDSSDSSDSS 1178

Query: 858  LPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGS 917
              + S     ++D  D   ++  S SS+ + S+  S D SD  D++     S    S+ S
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS-DSSDSSDSSDSSDSSDSSDSNESSDS 1237

Query: 918  GSPSATSILQKKETSFGSSENITMTS 943
               S +S       S  SS++   TS
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTS 1263



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 91/448 (20%), Positives = 160/448 (35%), Gaps = 26/448 (5%)

Query: 669  DFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSS------ISSEQKPD-----DKYDALKE 717
            DF + S+ G+    +     +D A+  + +NSS       +S++  D     D   A  +
Sbjct: 454  DFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDD 513

Query: 718  EASPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFA 777
            ++     T+N  S    G N    + K D  +  S         D  D++ S  S D   
Sbjct: 514  DSDSTSDTNNSDSN-GNGNNGNDDNDKSDSGKGKSDSSDS----DSSDSSNSSDSSDSSD 568

Query: 778  DFHSSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFD 837
               S   SS +SD S  + + +      DS++       S    S    DS D+ S    
Sbjct: 569  SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628

Query: 838  MKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLT----- 892
             +      D K   SDSS    + S  +  ++D  +   ++  S SS+ + S+ +     
Sbjct: 629  SESDSSDSDSK---SDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685

Query: 893  SYDWSDRDDATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKVTTFVS 952
            S D SD  D++   + S    S  S S S+ S       S  S  + +  S     +  S
Sbjct: 686  SSDSSDSSDSSNSSESSD--SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS 743

Query: 953  EDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGA 1012
             D+   +     +   D+   +      ++ D  D +         +   +  S  SS +
Sbjct: 744  SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDS 803

Query: 1013 SQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKR 1072
            S  + +  S D  +  S     S      + S +   SS+    S+ +  D S +     
Sbjct: 804  SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863

Query: 1073 SLSLGDKEISRSSPSPALEQPFRDRSNT 1100
            S    D   S +S   +      + SN+
Sbjct: 864  SSDSSDSSDSSNSSDSSDSSDSNESSNS 891



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 68/349 (19%), Positives = 125/349 (35%), Gaps = 17/349 (4%)

Query: 438  SSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQELPASSKTSNSQHGNSAPS 497
            SS    +  +N     +  +  D  D+S S    DS        +S  + +S   NS+ S
Sbjct: 962  SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021

Query: 498  LLMPLPGTKALPSMDKYAVFKGIAADKS----SENTVPPGDPGDKYSAFRELEQTAENKP 553
                     +  S    +     ++D S    S N+    D  D  S   +   ++++  
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS-SDSSDSSDSSDSSD 1080

Query: 554  LGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKDKTFPPSFPSGTIQQKQQTQVKNPLN 613
              ES     S+ + D      ++DS    +      +   S  S +      +   +  N
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140

Query: 614  LADLDMFSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF 673
             +D    S  + SS+   S  +  S+  S S+  S  S +     + +  SS + D  + 
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS-----SDSSDSSDSSDSSDS 1195

Query: 674  SLFGEYSGLAPVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGSTVK 733
            S   + S  +   +  D +D    S+SS SS+   D    +   ++S    +SN   +  
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS-DSNESSDSSDSSDSSDSSNSSDSSD 1254

Query: 734  GGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSS 782
               +S + S   D     S  G+G       +N     SD + +D + S
Sbjct: 1255 SSDSSDSTSDSNDESDSQSKSGNG------NNNGSDSDSDSEGSDSNHS 1297


>gi|148612857 sickle tail isoform 3 [Homo sapiens]
          Length = 1309

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 103/473 (21%), Positives = 173/473 (36%), Gaps = 64/473 (13%)

Query: 38   PQAGLMPMQQQGFPMVSVMQPNMQGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLG 97
            P +G+M    Q  P+V  +QP+   +  +N +  +        A  P  P  A     + 
Sbjct: 843  PLSGMMVRHAQSSPVV--IQPSQHSVALLNPAQNLPH-----VASSPAVPQEATSTLQMS 895

Query: 98   QAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVK 157
            QAP     P  P     MQ  F EE       + + +  E+  +++EE++Q L       
Sbjct: 896  QAP---QSPQIPMNGSAMQSLFIEEIHS-VSAKNRAVSIEKAEKKWEEKRQNL---DHYN 948

Query: 158  PKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQ 217
             K  EK  ++A   I  ++        +   PA+ P   G +  +K  +S D   S Q+ 
Sbjct: 949  GKEFEKLLEEAQANIMKSIPN------LEMPPATGPLPRGDAPVDKVELSEDSPNSEQDL 1002

Query: 218  IKLNTSEVGHKALGPGSSKKYPSLMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVG 277
             KL     G K+  P       S +  +G+          T   EN + +  S E++G  
Sbjct: 1003 EKL-----GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK-ASSEDAGPS 1056

Query: 278  V------FPSQDPAQ---PRMPPWIYNESLVPDAYK----KILETTMTPTGIDTAKLYPI 324
                   +P+++PA    P  PP   + S   +  +    KI+      +G       P+
Sbjct: 1057 PQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPV 1116

Query: 325  LMSSGLPRETLGQIWALANRTTP-------GKLTKEELYTVLAMIAVTQRGVPAMSPDAL 377
             MS+     TL +    +    P       G   K          ++    +PA+SP + 
Sbjct: 1117 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSG 1176

Query: 378  NQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAGSMPLSLGQPVMGINLVGPVGGAAAQA 437
                ++ +P+ SG S  LP P   P   PS  +  +    G P    +L+  V   + + 
Sbjct: 1177 K---SSSLPSSSGDSSNLPNP---PATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKF 1230

Query: 438  SSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDD--SFSDFQELPASSKTSN 488
             S          +    +     F   S++G      SFS     PASS + N
Sbjct: 1231 QS----------LTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLN 1273


>gi|148612813 sickle tail isoform 2 [Homo sapiens]
          Length = 1264

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 103/473 (21%), Positives = 173/473 (36%), Gaps = 64/473 (13%)

Query: 38   PQAGLMPMQQQGFPMVSVMQPNMQGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLG 97
            P +G+M    Q  P+V  +QP+   +  +N +  +        A  P  P  A     + 
Sbjct: 798  PLSGMMVRHAQSSPVV--IQPSQHSVALLNPAQNLPH-----VASSPAVPQEATSTLQMS 850

Query: 98   QAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVK 157
            QAP     P  P     MQ  F EE       + + +  E+  +++EE++Q L       
Sbjct: 851  QAP---QSPQIPMNGSAMQSLFIEEIHS-VSAKNRAVSIEKAEKKWEEKRQNL---DHYN 903

Query: 158  PKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQ 217
             K  EK  ++A   I  ++        +   PA+ P   G +  +K  +S D   S Q+ 
Sbjct: 904  GKEFEKLLEEAQANIMKSIPN------LEMPPATGPLPRGDAPVDKVELSEDSPNSEQDL 957

Query: 218  IKLNTSEVGHKALGPGSSKKYPSLMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVG 277
             KL     G K+  P       S +  +G+          T   EN + +  S E++G  
Sbjct: 958  EKL-----GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK-ASSEDAGPS 1011

Query: 278  V------FPSQDPAQ---PRMPPWIYNESLVPDAYK----KILETTMTPTGIDTAKLYPI 324
                   +P+++PA    P  PP   + S   +  +    KI+      +G       P+
Sbjct: 1012 PQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPV 1071

Query: 325  LMSSGLPRETLGQIWALANRTTP-------GKLTKEELYTVLAMIAVTQRGVPAMSPDAL 377
             MS+     TL +    +    P       G   K          ++    +PA+SP + 
Sbjct: 1072 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSG 1131

Query: 378  NQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAGSMPLSLGQPVMGINLVGPVGGAAAQA 437
                ++ +P+ SG S  LP P   P   PS  +  +    G P    +L+  V   + + 
Sbjct: 1132 K---SSSLPSSSGDSSNLPNP---PATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKF 1185

Query: 438  SSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDD--SFSDFQELPASSKTSN 488
             S          +    +     F   S++G      SFS     PASS + N
Sbjct: 1186 QS----------LTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLN 1228


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 37/119 (31%), Positives = 48/119 (40%), Gaps = 17/119 (14%)

Query: 6   GAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFP-MVSVMQPN-MQGI 63
           GAG GGGG  G G G AGGGG      GG++P  A +     +G P  V ++Q + MQG 
Sbjct: 28  GAGGGGGGGGGGGGGGAGGGG------GGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGA 81

Query: 64  MGMNYSSQMSQGPIAMQAGIPMGPMPA---------AGMPYLGQAPFLGMRPPGPQYTP 113
           M  +    M          +P     A         A  P+ G A  +   P  P   P
Sbjct: 82  MAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPP 140



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 1/46 (2%)

Query: 5   PGAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGF 50
           PG G G   AA A A +A     +  +AGG +PP   L+  Q  GF
Sbjct: 184 PG-GWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGF 228


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 179/889 (20%), Positives = 298/889 (33%), Gaps = 125/889 (14%)

Query: 181  RDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGHKALGPGSSKKYPS 240
            +    H +P S      P+      VS + +TS       +T+        PG S+   +
Sbjct: 3605 KSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 3664

Query: 241  LMASNG----------VAVDGCVSGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQPRMP 290
              +S G              G    +TT+ + + S        S   +   Q+       
Sbjct: 3665 SHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSS 3724

Query: 291  PWIYNESLVPDAYKK--ILETTM---TPTGIDTAKLYPILMSS-GLPRE-TLGQIWALAN 343
            P   + +L PD+     I+E +    + TG     L P   +S GL  E T  Q    + 
Sbjct: 3725 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 3784

Query: 344  RTTPGKLTKEELYTVLAMIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQPT 403
             TTP   +     T     + T    P  +P     FPA+   T SG S       S P 
Sbjct: 3785 HTTP---SPPSTATAPVEESTTYHRSPGSTPTT--HFPASS--TTSGHSEKSTIFHSSPD 3837

Query: 404  VIPSGPAGSMPLSLGQPVMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQD 463
               + P+ +   + G+     + + P         S  I T P +       +    F  
Sbjct: 3838 ASGTTPSSAHSTTSGRGESTTSRISP--------GSTEITTLPGSTTTPGLSEASTTFYS 3889

Query: 464  ASKSGSLDDSFSDFQELPAS--SKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIA 521
            + +S +   S +    L     S TS SQ G++  ++    P +   P + + +     +
Sbjct: 3890 SPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS---PASTTTPGLSEESTTVYSS 3946

Query: 522  ADKSSENTVPPGDPGDKYSAFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSP 581
            +  S+E TV P       S  RE   T  ++P       F    T  G T+  TA     
Sbjct: 3947 SPGSTETTVFPRSTTT--SVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA----- 3999

Query: 582  LEPPTKDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSK 641
                     FP S P+ T     QT +   L  ADL                       +
Sbjct: 4000 ---------FPGS-PAST-----QTGLPATLTTADLG---------------------EE 4023

Query: 642  SVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSS 701
            S + P S+GS  T  + A + TS L  +     L    +    +            S + 
Sbjct: 4024 STTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTF 4083

Query: 702  ISSEQKPDDKYDALKEEASPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVE 761
             +S + PD          SP   TS+  S      +S   ST    F   S   SGL  E
Sbjct: 4084 YTSPRSPD-------ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPD-STTTSGLSQE 4135

Query: 762  DLKDNTPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGG- 820
                ++  G ++       ++      +  SLG+++  F  +  D+ +    D     G 
Sbjct: 4136 PTTSHSSQGSTE-------ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL 4188

Query: 821  --SSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAA 878
              +S     S  +L        +   G  +   +  S    + +   PP+     ++ + 
Sbjct: 4189 VEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVST 4248

Query: 879  FGSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSP--------SATSILQKKE 930
              +Y S  + +  T +  S     T GR      + +  G+         SATS+L  + 
Sbjct: 4249 --TYHSRPSSTPTTHFSAS---STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP 4303

Query: 931  T----SFGSSE------NITMTSLS-KVTTFVSEDALPETTFPALASFKDTIPQ---TSE 976
            T    S GS+E      + T   LS K TTF S    P+TT    ++    + +   TS 
Sbjct: 4304 TTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 4363

Query: 977  QKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNECSDDFG 1025
             +          +   +P   +   A+  SP S+  +    +  +   G
Sbjct: 4364 SRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG 4412



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 173/885 (19%), Positives = 302/885 (34%), Gaps = 110/885 (12%)

Query: 181  RDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGHKALGPGSSKKYPS 240
            +    H +P S      P+      VS + +TS       +T+        PG S+   +
Sbjct: 2048 KSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 2107

Query: 241  LMASNGVAVDGCV--SGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQPRMPPWIYNESL 298
              +S G      +  S TT+  ++ ++  + S   +   + P    A           S 
Sbjct: 2108 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS 2167

Query: 299  VPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTV 358
                +  +   + T +GI  A    +  S+G PR TL      A+ T+PG   +   +  
Sbjct: 2168 PGSTHTTLFPDSTTSSGIVEASTR-VHSSTGSPRTTLSP----ASSTSPGLQGESTAFQT 2222

Query: 359  LAMIAVTQRGVPAMSPDALNQF------PAAPIPTLSGFSMTLPTPVSQPTVIPSGP--A 410
                  T    P+ +   + +       P +   T    S T      + T+  S P  +
Sbjct: 2223 HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 2282

Query: 411  GSMPLSLGQPVMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSL 470
            G+ P S      G    G    +     S  I T P +       +    F  + +S + 
Sbjct: 2283 GTTPSSAHSTTSGR---GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 2339

Query: 471  DDSFSDFQELPAS--SKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSEN 528
              S +    L     S TS SQ G++  ++    P +   P + + +     ++  S+E 
Sbjct: 2340 TLSPASMTSLGVGEESTTSRSQPGSTHSTVS---PASTTTPGLSEESTTVYSSSPGSTET 2396

Query: 529  TVPPGDPGDKYSAFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKD 588
            TV P  P    S   E   T  ++P       F    T  G T+  TA            
Sbjct: 2397 TVFPRTPTT--SVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA------------ 2442

Query: 589  KTFPPSFPSGTIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVSTPQS 648
              FP S P+ T     QT +   L  ADL                       +S + P S
Sbjct: 2443 --FPGS-PAST-----QTGLPATLTTADLG---------------------EESTTFPSS 2473

Query: 649  TGSAATMTALAATKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISSEQKP 708
            +GS  T  + A + TS L  +     L    +    +            S +  +S + P
Sbjct: 2474 SGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP 2533

Query: 709  DDKYDALKEEASPVPLTSNVGSTVKGGQNSTA---ASTKYDVFRQLSLEGSGLGVEDL-- 763
            D         +S V   S+   +  G  ++TA   ++T   + R  +   S  G  D   
Sbjct: 2534 DATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 2593

Query: 764  --KDNTPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGS 821
                 T SG S +     HSS  S   +D +L   +       ++S +  S   P    +
Sbjct: 2594 LPASTTTSGPSQESTTS-HSSPGS---TDTALSPGSTTALSFGQESTTFHS--SPGSTHT 2647

Query: 822  SVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQ------HP--------- 866
            ++  + +  +  V+   ++    G  +  +S +S   P + G+      HP         
Sbjct: 2648 TLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSP 2707

Query: 867  ------PAADIEDLKYAAFGSYSSNFAVSTLTSYD------WSDRDDATQGRKLSPFVLS 914
                  P  +      +   + +++F  S+ TS        +    DA+     S    +
Sbjct: 2708 PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 2767

Query: 915  AGSGSPSATSILQKKETSFGSSENITMT-SLSKV-TTFVSEDALPETTF-PALASFKDTI 971
            +G G  S TS +    T   +    T T  LS+  TTF S    P TT  PA  +     
Sbjct: 2768 SGRGE-STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 2826

Query: 972  PQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQET 1016
             +++  +      +   +     T   S+E+T    +S G+++ T
Sbjct: 2827 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETT 2871



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 165/829 (19%), Positives = 277/829 (33%), Gaps = 108/829 (13%)

Query: 181  RDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGHKALGPGSSKKYPS 240
            R    H +P S      P+      VS + +TS       +T+        PG S+   +
Sbjct: 965  RSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTT 1024

Query: 241  LMASNGVAVDGCV--SGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQPRMPPWIYNESL 298
              +S G      +  S TT+  ++ ++  + S   +   + P    A           S 
Sbjct: 1025 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSN 1084

Query: 299  VPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTV 358
                +  +   + T +GI  A    +  S+G PR TL      A+ T+PG   +   +  
Sbjct: 1085 PGSTHTTLFPDSTTSSGIVEASTR-VHSSTGSPRTTLSP----ASSTSPGLQGESTAFQT 1139

Query: 359  LAMIAVTQRGVPAMSPDALNQF------PAAPIPTLSGFSMTLPTPVSQPTVIPSGP--A 410
                  T    P+ +   + +       P +   T    S T      + T+  S P  +
Sbjct: 1140 HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 1199

Query: 411  GSMPLSLGQPVMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSL 470
            G+ P S      G    G    +     S  I T P +       +    F  + +S + 
Sbjct: 1200 GTTPSSAHSTTSGR---GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 1256

Query: 471  DDSFSDFQELPAS--SKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSEN 528
              S +    L     S TS SQ G++  ++    P +   P + + +     ++  S+E 
Sbjct: 1257 TLSPASMTSLGVGEESTTSRSQPGSTHSTVS---PASTTTPGLSEESTTVYSSSRGSTET 1313

Query: 529  TVPPGDPGDKYSAFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKD 588
            TV P       S   E   T  ++P       F    T  G T+  TA            
Sbjct: 1314 TVFPHSTTT--SVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA------------ 1359

Query: 589  KTFPPSFPSGTIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVSTPQS 648
              FP S P+ T     QT +   L  ADL                       +S + P S
Sbjct: 1360 --FPGS-PAST-----QTGLPATLTTADLG---------------------EESTTFPSS 1390

Query: 649  TGSAATMTALAATKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISSEQKP 708
            +GS  T  + A + TS L  +     L    +    +            S +  +S + P
Sbjct: 1391 SGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP 1450

Query: 709  DDKYDALKEEASPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTP 768
            D          SP   TS+  S      +S   ST    F   S   S L  E    ++ 
Sbjct: 1451 D-------ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPD-STTTSDLSQEPTTSHSS 1502

Query: 769  SGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGG---SSVGK 825
             G ++       ++      +  SLG+++  F  +  D+ +    D     G   +S   
Sbjct: 1503 QGSTE-------ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 1555

Query: 826  EDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSN 885
              S  +L        +   G  +   +  S    + +   PP      ++ +   +Y S 
Sbjct: 1556 HSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVST--TYHSR 1613

Query: 886  FAVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSP--------SATSILQKKET----SF 933
             + +  T +  S     T GR      + +  G+         SATS+L  + T    S 
Sbjct: 1614 PSSTPTTHFSAS---STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISS 1670

Query: 934  GSSE------NITMTSLS-KVTTFVSEDALPETTFPALASFKDTIPQTS 975
            GS+E      + T   LS K TTF S    P+TT    ++    + + S
Sbjct: 1671 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEES 1719



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 215/1054 (20%), Positives = 348/1054 (33%), Gaps = 170/1054 (16%)

Query: 180  SRDAKMHPTPASHPKKPGPSLEEKFLV-SCDISTSGQEQIKLNTSEVGHKALGPGSSKKY 238
            SR A  H T  +         EE         ST       L T+++G +      S  +
Sbjct: 1334 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE------STTF 1387

Query: 239  PSLMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVGVFPSQD--PAQPRMPPWIYNE 296
            PS   S G  +    S T+    E+T  + LS   +     P     P+        Y  
Sbjct: 1388 PSSSGSTGTKLSPARSTTSGLVGESTPSR-LSPSSTETTTLPGSPTTPSLSEKSTTFYTS 1446

Query: 297  SLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELY 356
               PDA   +   T T +G+          S   P  T     A  + TT   L++E   
Sbjct: 1447 PRSPDA--TLSPATTTSSGVSEESS----TSHSQPGST--HTTAFPDSTTTSDLSQE--- 1495

Query: 357  TVLAMIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAGSMPLS 416
                             P   +    +   TLS  S T  +   Q T   S P  +    
Sbjct: 1496 -----------------PTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTL 1538

Query: 417  LGQPVMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSD 476
            L    +   LV         +S+G + T      + P          +S S  L +  + 
Sbjct: 1539 LPDDTITSGLVE--ASTPTHSSTGSLHT-----TLTPA---------SSTSAGLQEESTT 1582

Query: 477  FQELPASSKTSNSQHG-NSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENTVPPGDP 535
            FQ  P+SS T+ S  G  +AP  +     ++   +   +         +S E+T     P
Sbjct: 1583 FQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 1642

Query: 536  GDKYSAFRELEQTAENKPLGESFAEFRSAG-----------TDDGFTDFKTADSVSPLEP 584
            G   +A     ++A +  +GE      S+G           T  G ++  T    SP  P
Sbjct: 1643 GATGTALFP-TRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 1701

Query: 585  PTKDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVS 644
             T     P S  S  + ++  T    P              ++  P S +    + +S +
Sbjct: 1702 DT--TLSPASTTSSGVSEESTTSHSRP----------GSTHTTAFPGSTTMPGVSQESTA 1749

Query: 645  TPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISS 704
            +  S GS  T  +  +T  SSL  +   F      +    + +    +  +  S    SS
Sbjct: 1750 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS 1809

Query: 705  EQKPDDKYDALKEEASPVPLTSNVGSTVKGGQNST------------AASTKYDVFRQLS 752
                           SP    S  GST + G+++T            A  T    F +LS
Sbjct: 1810 -------------TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS 1856

Query: 753  LEGSGL-----GVEDLKDNTPSGKSDDDFADFHSSKFSSI-------NSDKSLGEKAVAF 800
                G             +T  G+S++     HSS  ++        ++   L E++ A+
Sbjct: 1857 TTSHGSPSSTPTTHFSASSTTLGRSEES-TTVHSSPVATATTPSPARSTTSGLVEESTAY 1915

Query: 801  RHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPT 860
              +   + ++   +  +  G S     S  + +       +     ++   S  S    T
Sbjct: 1916 HSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGST 1975

Query: 861  VSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSP 920
             +   P ++        +  S+SS  A  T+     S           SP  +S+GS   
Sbjct: 1976 ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP--ISSGSMET 2033

Query: 921  SA------TSILQKKETSFGSSENITMTSLSKVTTF---VSEDALPETTFPA---LASFK 968
            +A      T  L +K T+F SS     T+LS  +T    VSE++    + P      +F 
Sbjct: 2034 TALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 2093

Query: 969  D--TIPQTSEQKEYENRDYKDFTKQDLP----TAERSQEATC--PSPASSGASQETPNEC 1020
            D  T P  S      +          LP    T+  SQE+T    SP S+  +    +  
Sbjct: 2094 DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTT 2153

Query: 1021 SDDFGE----FQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSL 1076
            +  FG+    F S         F  +T+ S +  +   + S          GS + +LS 
Sbjct: 2154 ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSS--------TGSPRTTLS- 2204

Query: 1077 GDKEISRSSPSPALE---QPFRDRSNTLNEKPALPVIRDKYKDLTGEVEENERYAYEWQR 1133
                   SS SP L+     F+    + +  P+ P         T  VEE+  Y     R
Sbjct: 2205 -----PASSTSPGLQGESTAFQTHPASTHTTPSPP------STATAPVEESTTY----HR 2249

Query: 1134 CLGSALNVIKKANDTLNGISSSSVCTEVIQSAQG 1167
              GS       A+ T +G S  S        A G
Sbjct: 2250 SPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 2283



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 215/1051 (20%), Positives = 350/1051 (33%), Gaps = 164/1051 (15%)

Query: 180  SRDAKMHPTPASHPKKPGPSLEEKFLV-SCDISTSGQEQIKLNTSEVGHKALGPGSSKKY 238
            SR A  H T  +         EE         ST       L T+++G +      S  +
Sbjct: 2891 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE------STTF 2944

Query: 239  PSLMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVGVFPSQD--PAQPRMPPWIYNE 296
            PS   S G  +    S T+    E+T  + LS   +     P     P+        Y  
Sbjct: 2945 PSSSGSTGTTLSPARSTTSGLVGESTPSR-LSPSSTETTTLPGSPTTPSLSEKSTTFYTS 3003

Query: 297  SLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELY 356
               PDA      TT                SSG+  E+        + + PG       +
Sbjct: 3004 PRSPDATLSPATTT----------------SSGVSEESS------TSHSQPGST-----H 3036

Query: 357  TVLAMIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAGSMPLS 416
            T     + T  G+ +  P A +    +   TLS  S T  +   Q T   S P  +    
Sbjct: 3037 TTAFPDSTTTSGL-SQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTL 3095

Query: 417  LGQPVMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSD 476
            L    +   LV         +S+G + T      + P          +S S  L +  + 
Sbjct: 3096 LPDDTITSGLVE--ASTPTHSSTGSLHT-----TLTPA---------SSTSAGLQEESTT 3139

Query: 477  FQELPASSKTSNSQHG-NSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENTVPPGDP 535
            FQ  P+SS T+ S  G  +AP  +     ++   +   +         +S E+T     P
Sbjct: 3140 FQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 3199

Query: 536  GDKYSAFRELEQTAENKPLGESFAEFRSAG-----------TDDGFTDFKTADSVSPLEP 584
            G   +A     ++A +  +GE      S+G           T  G ++  T    SP  P
Sbjct: 3200 GATGTALFP-TRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 3258

Query: 585  PTKDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVS 644
             T     P S  S  + ++  T    P              ++  P S +    + +S +
Sbjct: 3259 DT--TLSPASTTSSGVSEESTTSHSRP----------GSTHTTAFPGSTTMPGVSQESTA 3306

Query: 645  TPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADFMAFSNSSISS 704
            +  S GS  T  +  +T  SSL  +   F   G  S    +   +  A  +  +++ + S
Sbjct: 3307 SHSSPGSTDTTLSPGSTTASSLGPESTTFH-SGPGSTETTLLPDNTTASGLLEASTPVHS 3365

Query: 705  EQKPDDKYDALKEEASPVPLTSNVGSTVKGGQNST------------AASTKYDVFRQLS 752
                           SP    S  GST + G+++T            A  T    F +LS
Sbjct: 3366 ------------STGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELS 3413

Query: 753  LEGSGL-----GVEDLKDNTPSGKSDDDFADFHSSKFSSI-------NSDKSLGEKAVAF 800
                G             +T  G+S++     HSS  ++        ++   L E++  +
Sbjct: 3414 TTSHGSPSSTPTTHFSASSTTLGRSEES-TTVHSSPVATATTPSPARSTTSGLVEESTTY 3472

Query: 801  RHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPT 860
              +   + ++   +  +  G       S  + +       +     ++   S  S    T
Sbjct: 3473 HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST 3532

Query: 861  VSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSP 920
             +   P ++        +  S+SS  A  T+     S           SP  +S+GS   
Sbjct: 3533 ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP--ISSGSMET 3590

Query: 921  SA------TSILQKKETSFGSSENITMTSLSKVTTF---VSEDALPETTFPA---LASFK 968
            +A      T  L +K T+F SS     T+LS  +T    VSE++    + P      +F 
Sbjct: 3591 TALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 3650

Query: 969  D--TIPQTSEQKEYENRDYKDFTKQDLP----TAERSQEATCPSPASSGASQETPNECSD 1022
            D  T P  S      +          LP    T+  SQE+T  S +SSG++    +  S 
Sbjct: 3651 DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQEST-TSHSSSGSTDTALSPGST 3709

Query: 1023 DFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKEIS 1082
                F  E            T  S   S+   +  +  T    V+ S +   S G    +
Sbjct: 3710 TALSFGQES----------TTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 3759

Query: 1083 ---RSSPSPALE---QPFRDRSNTLNEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLG 1136
                SS SP L+     F+    + +  P+ P         T  VEE+  Y     R  G
Sbjct: 3760 LSPASSTSPGLQGESTAFQTHPASTHTTPSPP------STATAPVEESTTY----HRSPG 3809

Query: 1137 SALNVIKKANDTLNGISSSSVCTEVIQSAQG 1167
            S       A+ T +G S  S        A G
Sbjct: 3810 STPTTHFPASSTTSGHSEKSTIFHSSPDASG 3840


>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
            sapiens]
          Length = 1782

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 94/433 (21%), Positives = 154/433 (35%), Gaps = 50/433 (11%)

Query: 635  AVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYSGLAPVGEQDDFADF 694
            A+ ++  +    Q  G  +T+  +A     SL     E  L G+   L   G  +   + 
Sbjct: 45   AIAASDPATKLLQKNGQLSTINGVAEQDELSLQ----EGDLNGQKGALNGQGALNSQEEE 100

Query: 695  MAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLE 754
                      + +   K D+ KE A+   +  ++      GQ  T      ++  Q+   
Sbjct: 101  EVIVTEVGQRDSEDVSKRDSDKEMATKSAVVHDI---TDDGQEETP-----EIIEQIPSS 152

Query: 755  GSGLGVEDLKDNTPSGKSDDDFAD---FHSSKFSSINSDKSLGEKAVAFRHTKED----S 807
             S L  E+L   T S  +D  F     F   KF+ +  DK+     V     K+D    +
Sbjct: 153  ESNL--EELTQPTESQANDIGFKKVFKFVGFKFT-VKKDKTEKPDTVQLLTVKKDEGEGA 209

Query: 808  ASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPP 867
            A       PS+G      ++SE   S +   +       LK   S + +  P  SGQ   
Sbjct: 210  AGAGDHKDPSLGAGEAASKESEPKQSTEKPEET------LKREQSHAEISPPAESGQAVE 263

Query: 868  AADIE-DLKYAAFGSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSPSATSIL 926
                E + K     S S+    S +TS           G     F     +G    TS  
Sbjct: 264  ECKEEGEEKQEKEPSKSAESPTSPVTS---------ETGSTFKKFFTQGWAGWRKKTSFR 314

Query: 927  QKKETSFGSSENITMTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYK 986
            + KE    +SE        KV T   ED   E     L + +   PQ   +  +E R   
Sbjct: 315  KPKEDEVEASEKKKEQEPEKVDT--EEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSA 372

Query: 987  DFTKQDLPTAERSQEATCPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQS 1046
            ++ K +LP+ E+          S G S+E P   +    E   EK ++ + + +     S
Sbjct: 373  EYEKVELPSEEQVS-------GSQGPSEEKPAPLAT---EVFDEKIEVHQEEVVAEVHVS 422

Query: 1047 KMKSSEEMIKSEL 1059
             ++   E  K+E+
Sbjct: 423  TVEERTEEQKTEV 435



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 5/168 (2%)

Query: 907  KLSPFVLSAGSGSPSATSILQKKETS--FGSSENITMTSLSKVTTFVS-EDALPETTFPA 963
            K +P ++SA +    ++ +  +K TS  + S E     +  +V   V+ ED  PE     
Sbjct: 1482 KSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIEDLEPENGILE 1541

Query: 964  LASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNECSDD 1023
            L +    + Q   Q   +     + T  ++ T+E   +A      S  A QET  E  + 
Sbjct: 1542 LETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEP 1601

Query: 1024 FGEFQSEKPKISKFDFLVATS--QSKMKSSEEMIKSELATFDLSVQGS 1069
                Q E P  S  +   +T+  Q+    S++M ++   T  + V+GS
Sbjct: 1602 QASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGS 1649


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 116/538 (21%), Positives = 192/538 (35%), Gaps = 78/538 (14%)

Query: 253  VSGTTTAEAE-NTSDQNLSIEESGVGVFPSQDPAQPR------MPPWIYNESLVPDAYKK 305
            VS TT A +E NT    L+   + V  + SQ  + P       MP   Y+E   P     
Sbjct: 1933 VSTTTVASSEINTLSTTLADTRTPVTTY-SQASSSPTTADGTSMPTPAYSEGSTPLTSMP 1991

Query: 306  ILETTMTPTGIDTAKLYPILMSSGLPRETLGQIW-ALANRTTPGKLTKEELYTVLAMIAV 364
            +  T +  +   T    P+  S+     T G      A  T+    T  E  T LA + V
Sbjct: 1992 LSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPV 2051

Query: 365  TQRGVPAMSPDALNQFP------------AAPIPTLSGFSMTLPTPVSQPTVIPSGPAGS 412
            +   V +   + L+  P            A+   T  G SMT+  P     ++ S P  +
Sbjct: 2052 STTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLST 2111

Query: 413  MPLSLGQPVMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDD 472
             P++   P        PV   +   +S  + + P    +  E    Q             
Sbjct: 2112 TPVA--SPEASTLSTTPVDSNSPVITSTEVSSSP----IPTEGTSMQT-----------S 2154

Query: 473  SFSDFQELPASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENT-VP 531
            ++SD +    S   S +   +SA S L   P   + P  +     +  ++  +SE T +P
Sbjct: 2155 TYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNST---EARSSPTTSEGTSMP 2211

Query: 532  PGDPGDKYSAFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKDKTF 591
               P +  + F  +       P+  S A   SA   D  T   T+   +   P T + T 
Sbjct: 2212 TSTPSEGSTPFTSMP--VSTMPVVTSEASTLSATPVDTSTPVTTSTEATS-SPTTAEGT- 2267

Query: 592  PPSFPSGTIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGS 651
              S P+ T+ +        P++   L   S V+  S  P+  +  F+TS   S+P  T  
Sbjct: 2268 --SIPTSTLSEGTTPLTSIPVSHT-LVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAE 2324

Query: 652  AATM-------------------TALAATKTSSL----ADDFGEFSLFGEYSGLAPVGEQ 688
              +M                   T +A+ +TS+L    AD     + + + +G +P    
Sbjct: 2325 GTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQ-AGSSPTTAD 2383

Query: 689  DDFADFMAFSNSSISSEQKPDDKYDALKEEAS-----PVPLTSNVGSTVKGGQNSTAA 741
            D       +S  S      P      +  EAS     PV  ++ V ++ +   + T A
Sbjct: 2384 DTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTA 2441



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 146/788 (18%), Positives = 270/788 (34%), Gaps = 89/788 (11%)

Query: 210 ISTSGQEQIKLNTSEVGHKALGPGSSKKYPSLMASNGVAVDGCVSGTTTAEAENTSDQNL 269
           +ST  +E I    + V    L   S + Y SL     V +   ++ +T A +  T+ ++ 
Sbjct: 149 MSTPSEESISSTMAFVSTAPLP--SFEAYTSLTYK--VDMSTPLTTSTQASSSPTTPEST 204

Query: 270 SIEESGVGVFPSQDPAQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSG 329
           +I        P    ++   P      S +  A  + +    TP  I T        SS 
Sbjct: 205 TI--------PKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSS 256

Query: 330 LPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRGVPAMSPDALNQFP------AA 383
               T  +  +L+N    G  T      +  M+ V+       +  A    P      A+
Sbjct: 257 ---PTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEAS 313

Query: 384 PIPTLS-GFSMTLPTPVSQPTVIPSGPAGSMPLSLGQPVMGINLVGPVGGAAAQASSGFI 442
             PT + G S+   T     T + S PA +MP++  +  M    + PV  +    +S   
Sbjct: 314 SSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSE--MSTLSITPVDTSTLVTTS--- 368

Query: 443 PTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQELPASSKTSNSQHGNSAPSLLMPL 502
            T P++     E         +  + +L +  +    +P S+    S   ++  ++ +  
Sbjct: 369 -TEPSSLPTTAE-------ATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPV-- 418

Query: 503 PGTKALPSMDKYAVFKGIAADKSSENTVPPGDPGDKYSAFRELEQTAENKPLGESFAEFR 562
             +K   +    A      A+ +S  T  P +     ++           P+  S A   
Sbjct: 419 -DSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTS-----MPVSTTPVASSEASNL 472

Query: 563 SAGTDDGFTDFKTADSVSPLEPPTKDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDMFSS 622
           S    D  T   T+   S   P  +  + P S PS           +    L  + + + 
Sbjct: 473 STTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPS-----------EGSTPLTSMSVSTM 521

Query: 623 VNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYSGL 682
              SSE     +    TS  V+T     S++T     +  TS+ ++     +     + L
Sbjct: 522 PVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRL 581

Query: 683 APVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGSTVKGGQNSTAAS 742
               E    +   A SN+ +++  +        +  + P    S  G+T+     ST   
Sbjct: 582 VVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLV 641

Query: 743 TKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRH 802
                    S E S L    +  NTP   S +  +   +++ +S+ +  +  E +     
Sbjct: 642 A--------SSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPT-STYTEGSTPLTS 692

Query: 803 TKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS 862
              ++  V S +  ++  + V   D+   ++   +   +    D       +S+   T S
Sbjct: 693 MPVNTTLVASSEASTLSTTPV---DTSTPVTTSTEASSSPTTAD------GASMPTSTPS 743

Query: 863 GQHPPAADIEDLKYAAFGSYSSNFAVSTL-------TSYDWSDRDDATQGRKLSPFVLSA 915
               P   +   K     S +S  + + L       TS + S     T+G  +   + + 
Sbjct: 744 EGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMP--ISTP 801

Query: 916 GSGSPSATSI------LQKKETSFGSSENITMTSLSKVTTFVSEDALPE--TTFPALASF 967
             GSP  TSI      +   E S  S+  +   S    +T VS    P   T+ P     
Sbjct: 802 SEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYS 861

Query: 968 KDTIPQTS 975
           +   P TS
Sbjct: 862 EGRTPLTS 869



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 89/448 (19%), Positives = 154/448 (34%), Gaps = 60/448 (13%)

Query: 240  SLMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQPRMPPWIYNESLV 299
            +L+A++ ++        T+    N+++   S   S     P+  P +   P     +S  
Sbjct: 875  TLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTT 934

Query: 300  PDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVL 359
            P    +    T++ T +DT+   P+  S+                +TP + T     T +
Sbjct: 935  PVVSSEA--RTLSATPVDTST--PVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPV 990

Query: 360  AMIAVTQRGVPAMS--------PDALNQFPAAPIPTLSGFSMTLPTPVSQPTVIPSGPAG 411
            +   V       +S        P   +   ++P PT  G SM   TP    T     P  
Sbjct: 991  SHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGST-----PLT 1045

Query: 412  SMPLSLGQPVMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLD 471
             MP+S                  A + +  + T PA+            +  AS S +  
Sbjct: 1046 RMPVSTTM--------------VASSETSTLSTTPAD-----TSTPVTTYSQASSSSTTA 1086

Query: 472  DSFSDFQELPASSKTSNSQHGNSAP-----------SLLMPLPGTKALP-SMDKYAVFKG 519
            D  S    +P S+ +  S    S P           S L   P   ++P +    A    
Sbjct: 1087 DGTS----MPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSP 1142

Query: 520  IAADKSSENTVPPGDPGDKYSAFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSV 579
              A+ +S  T PP + G    A   +  T     +  S A   S    D  T   T+   
Sbjct: 1143 TTAEGTSIPTSPPSE-GTTPLASMPVSTTL----VVSSEANTLSTTPVDSKTQVATSTEA 1197

Query: 580  SPLEPPTKDKTFPPSFPSGTIQQKQQTQVKN-PLNLADLDMFSSVNCSSEKPLSFSAVFS 638
            S   P  +  + P S P           V++ P+  ++    S+    +  P++ SA   
Sbjct: 1198 SSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSA--E 1255

Query: 639  TSKSVSTPQSTGSAATMTALAATKTSSL 666
            TS S +T + T    + T+  +T  +S+
Sbjct: 1256 TSSSPTTAEGTSLPTSTTSEGSTLLTSI 1283


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 3/90 (3%)

Query: 328 SGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRG--VPAMSPDALNQFPAAPI 385
           SGLP+  L QIWALA+    G++ + E    + +I +  +G  +P+  P  + Q P A I
Sbjct: 51  SGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVA-I 109

Query: 386 PTLSGFSMTLPTPVSQPTVIPSGPAGSMPL 415
            +   F M     +   T +   P GS+P+
Sbjct: 110 SSAPAFGMGGIASMPPLTAVAPVPMGSIPV 139



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 76/295 (25%), Positives = 121/295 (41%), Gaps = 38/295 (12%)

Query: 114 DMQKQFAEEQQKRFEQQQKLLE-----EERKRRQFEEQKQKLRLLSSVKPKTG-EKSRDD 167
           +++KQ  E Q++  E+ ++ LE     +E +R +   +++KL+   SVK K G EK + +
Sbjct: 641 ELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQE 700

Query: 168 ALEAIKGNLDGFSRDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGH 227
           A        D   R    H  PA    +   S  EK      ++ S QE +K+    V +
Sbjct: 701 A-------QDKLGRLFHQHQEPAKPAVQAPWSTAEK----GPLTISAQENVKV----VYY 745

Query: 228 KALGPGSSKKYPSLMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESG-VGVFPSQDPAQ 286
           +AL P  S+ +  +    G  V   V G    E++      L  E  G  G FP+     
Sbjct: 746 RALYPFESRSHDEITIQPGDIV--MVKGEWVDESQTGEPGWLGGELKGKTGWFPAN--YA 801

Query: 287 PRMPPWIYNESLVPDAYKKILETTMTPTGIDTAK--LYPILMSSGLPRETLGQIWALANR 344
            ++P     E+ VP   K + ++T  P      +    P+ ++S  P  T    WA  + 
Sbjct: 802 EKIP-----ENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTSSEPSTTPNN-WADFSS 855

Query: 345 TTPGKLTKEELYTVLAMIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPV 399
           T P   T E+  T        Q  +   S   L Q  A    T +G S   P+PV
Sbjct: 856 TWPTS-TNEKPETDNWDAWAAQPSLTVPSAGQLRQRSAFTPATATGSS---PSPV 906



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 20/47 (42%), Positives = 25/47 (53%)

Query: 324 ILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRGVP 370
           ILM S LP+  L  IW L++    GKLT EE    + +I V   G P
Sbjct: 248 ILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQP 294


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 3/90 (3%)

Query: 328 SGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRG--VPAMSPDALNQFPAAPI 385
           SGLP+  L QIWALA+    G++ + E    + +I +  +G  +P+  P  + Q P A I
Sbjct: 51  SGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVA-I 109

Query: 386 PTLSGFSMTLPTPVSQPTVIPSGPAGSMPL 415
            +   F M     +   T +   P GS+P+
Sbjct: 110 SSAPAFGMGGIASMPPLTAVAPVPMGSIPV 139



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 76/295 (25%), Positives = 121/295 (41%), Gaps = 38/295 (12%)

Query: 114 DMQKQFAEEQQKRFEQQQKLLE-----EERKRRQFEEQKQKLRLLSSVKPKTG-EKSRDD 167
           +++KQ  E Q++  E+ ++ LE     +E +R +   +++KL+   SVK K G EK + +
Sbjct: 641 ELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQE 700

Query: 168 ALEAIKGNLDGFSRDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGH 227
           A        D   R    H  PA    +   S  EK      ++ S QE +K+    V +
Sbjct: 701 A-------QDKLGRLFHQHQEPAKPAVQAPWSTAEK----GPLTISAQENVKV----VYY 745

Query: 228 KALGPGSSKKYPSLMASNGVAVDGCVSGTTTAEAENTSDQNLSIEESG-VGVFPSQDPAQ 286
           +AL P  S+ +  +    G  V   V G    E++      L  E  G  G FP+     
Sbjct: 746 RALYPFESRSHDEITIQPGDIV--MVKGEWVDESQTGEPGWLGGELKGKTGWFPAN--YA 801

Query: 287 PRMPPWIYNESLVPDAYKKILETTMTPTGIDTAK--LYPILMSSGLPRETLGQIWALANR 344
            ++P     E+ VP   K + ++T  P      +    P+ ++S  P  T    WA  + 
Sbjct: 802 EKIP-----ENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTSSEPSTTPNN-WADFSS 855

Query: 345 TTPGKLTKEELYTVLAMIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPV 399
           T P   T E+  T        Q  +   S   L Q  A    T +G S   P+PV
Sbjct: 856 TWPTS-TNEKPETDNWDAWAAQPSLTVPSAGQLRQRSAFTPATATGSS---PSPV 906



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 20/47 (42%), Positives = 25/47 (53%)

Query: 324 ILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRGVP 370
           ILM S LP+  L  IW L++    GKLT EE    + +I V   G P
Sbjct: 248 ILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQP 294


>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
            sapiens]
          Length = 1684

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 82/357 (22%), Positives = 130/357 (36%), Gaps = 46/357 (12%)

Query: 711  KYDALKEEASPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSG 770
            K D+ KE A+   +  ++      GQ  T      ++  Q+    S L  E+L   T S 
Sbjct: 19   KRDSDKEMATKSAVVHDI---TDDGQEETP-----EIIEQIPSSESNL--EELTQPTESQ 68

Query: 771  KSDDDFAD---FHSSKFSSINSDKSLGEKAVAFRHTKED----SASVKSLDLPSIGGSSV 823
             +D  F     F   KF+ +  DK+     V     K+D    +A       PS+G    
Sbjct: 69   ANDIGFKKVFKFVGFKFT-VKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGEA 127

Query: 824  GKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADIE-DLKYAAFGSY 882
              ++SE   S +   +       LK   S + +  P  SGQ       E + K     S 
Sbjct: 128  ASKESEPKQSTEKPEET------LKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSK 181

Query: 883  SSNFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMT 942
            S+    S +TS           G     F     +G    TS  + KE    +SE     
Sbjct: 182  SAESPTSPVTS---------ETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQ 232

Query: 943  SLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEA 1002
               KV T   ED   E     L + +   PQ   +  +E R   ++ K +LP+ E+    
Sbjct: 233  EPEKVDT--EEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVS-- 288

Query: 1003 TCPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSEL 1059
                  S G S+E P   +    E   EK ++ + + +     S ++   E  K+E+
Sbjct: 289  -----GSQGPSEEKPAPLAT---EVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEV 337



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 5/168 (2%)

Query: 907  KLSPFVLSAGSGSPSATSILQKKETS--FGSSENITMTSLSKVTTFVS-EDALPETTFPA 963
            K +P ++SA +    ++ +  +K TS  + S E     +  +V   V+ ED  PE     
Sbjct: 1384 KSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIEDLEPENGILE 1443

Query: 964  LASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNECSDD 1023
            L +    + Q   Q   +     + T  ++ T+E   +A      S  A QET  E  + 
Sbjct: 1444 LETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEP 1503

Query: 1024 FGEFQSEKPKISKFDFLVATS--QSKMKSSEEMIKSELATFDLSVQGS 1069
                Q E P  S  +   +T+  Q+    S++M ++   T  + V+GS
Sbjct: 1504 QASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGS 1551



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 59/308 (19%), Positives = 115/308 (37%), Gaps = 31/308 (10%)

Query: 822  SVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPA-ADIEDLKYAAFG 880
            +VG+ DSED      D ++A     +  +  D   + P +  Q P + +++E+L      
Sbjct: 8    TVGQRDSEDVSKRDSDKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPT-E 66

Query: 881  SYSSNFA---VSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSE 937
            S +++     V     + ++ + D T+       +         A      K+ S G+ E
Sbjct: 67   SQANDIGFKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGE 126

Query: 938  NITMTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAE 997
              +  S  K +T       PE T     S  +  P     +  E    +   KQ+   ++
Sbjct: 127  AASKESEPKQST-----EKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSK 181

Query: 998  RSQEATCPSPASSGAS-------------QETPNECSDDFGEFQSEKPKISKFDFLVATS 1044
             ++  T P  + +G++             ++T      +     SEK K  + + +    
Sbjct: 182  SAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEE 241

Query: 1045 QSKMK-SSEEMIKSELATFDLSVQGSHKRSLS-------LGDKEISRSSPSPALEQPFRD 1096
              K + +SE++  SE A      + +H+  LS       L  +E    S  P+ E+P   
Sbjct: 242  DGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPL 301

Query: 1097 RSNTLNEK 1104
             +   +EK
Sbjct: 302  ATEVFDEK 309


>gi|110349786 Alstrom syndrome 1 [Homo sapiens]
          Length = 4169

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 133/583 (22%), Positives = 214/583 (36%), Gaps = 128/583 (21%)

Query: 647  QSTGSAATMTALAATKTSSLADDFGEFSLFGEYS-------GLAPVGEQDDFADFMAFSN 699
            Q+TG A T+T+ + ++  + +  F + +L G            AP G  D        ++
Sbjct: 1512 QTTG-APTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAP-GPADQTTGIPTITS 1569

Query: 700  SSISSEQKPDDKYDA------LKEEASPVPLTSNVGSTVK------GGQNSTAASTKYDV 747
            +S S  +KP   Y        L EEA  V + S  G T K      G   S+A   K   
Sbjct: 1570 TSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVS--GPTEKKTDIPAGPLGSSALGEKPIT 1627

Query: 748  FRQLSLEGSGLGVEDLKDNTPSGKSDD--DFADFHSSKFSSINSDKSLGEKAVAFRHTKE 805
            F + +L  S L  E +K +   G +D   +    HS+ +S+        ++ ++  H  E
Sbjct: 1628 FYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPE 1687

Query: 806  DSASV--------KSLDLPSIGGSSVG---------------KEDSEDALSVQFDMKLAD 842
            ++  V        +  + PS+  S                   E +++AL V    + AD
Sbjct: 1688 EALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPAD 1747

Query: 843  VGGDLKHVMSD--SSLDLPTVSGQHP-PAADI--EDLKYAAF-GSYSSNFAVSTLTSYDW 896
                L  V S   S  + P +S Q   P + +  E LK +   G       VST+TS  +
Sbjct: 1748 QKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVTSTSY 1807

Query: 897  SDRD---------------------------DATQGRKLSPF---------VLSAGSGSP 920
            S R+                           D   G  + P          V+S     P
Sbjct: 1808 SHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSVISYEQELP 1867

Query: 921  SATSILQK---------KETSFGSSENITMTSLSKVTTF-------VSEDALPETTFPAL 964
              T +  K         ++T    + + + ++  K + F       V+E+AL     P  
Sbjct: 1868 DLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALNVFVVPGQ 1927

Query: 965  ASFKDTIPQTSEQKEYENRDYKD-FTKQDLPTAERSQEATCPSPASSGASQET--PNECS 1021
               K  IP T     Y  R+     ++Q+LP +  ++EA   SP S  A Q+T  P   S
Sbjct: 1928 GDRKTEIP-TVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAEQKTGIPIGLS 1986

Query: 1022 DDFGEFQSEKPKIS--------KFDFLVATSQSKMKSSEEMIKSELATFDLSV--QGSHK 1071
              +     EK KIS        K +F  AT  S  +  +  I + +   D     Q +  
Sbjct: 1987 SSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTPSQTAFH 2046

Query: 1072 RSLSLGDKEISRSSPSPALEQ--PFRDRSNTLNEKPALPVIRD 1112
             S S   K      P+   +Q  P RD+S  + +  A+P + D
Sbjct: 2047 SSYSQTVK------PNILFQQQLPDRDQSKGILKISAVPELTD 2083



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 110/494 (22%), Positives = 166/494 (33%), Gaps = 74/494 (14%)

Query: 579  VSPLEPPTKDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFS 638
            VS +  P   KT  P+ PS     +++  V     L D  +        E+ L  SAV  
Sbjct: 791  VSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHL-------PEEALKVSAVSG 843

Query: 639  TSKS-VSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYSGLAPV-GEQDDFADFMA 696
             +     TP  T +++  ++L    ++          L  E   ++ V G  D      +
Sbjct: 844  PADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPS 903

Query: 697  FSNSSISSEQKP---------DDKY--DALKEEASPVPLTSNVGSTVKGGQNSTAASTKY 745
              +S  S  +KP         D  +  +ALK  A  V      G T     NS + S K 
Sbjct: 904  APSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTG-TPTVSSNSHSHSEKS 962

Query: 746  DVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFAD---FHSSKFSSINSDKSLGEKAVAFRH 802
             VF Q  L  S L  E LK +   G +D          S  FS         ++     +
Sbjct: 963  SVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSY 1022

Query: 803  TKEDSASVKS--------LDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDS 854
              E +  V +         ++P++  SS  + +    L  Q              V+SDS
Sbjct: 1023 ATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQ--------------VLSDS 1068

Query: 855  SLDLPT--VSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDATQGRKLS--P 910
             L   +  VS    PA  + D        YS              +     +  K+S  P
Sbjct: 1069 HLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAP 1128

Query: 911  FVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKVTTFVSEDALPETTFPALASFKDT 970
             +    +G+P+ TS      TS+            K + F  + ALP T  P  A     
Sbjct: 1129 GLADQKTGTPTVTS------TSYSQHRE-------KPSIF-HQQALPGTHIPEEAQKVSA 1174

Query: 971  IPQTSEQKE---------YENRDYKD-FTKQDLPTAERSQEATCPSPASSGASQETPNEC 1020
            +     QK          Y  R+    F +Q LP +   +EA   SP    A Q+T    
Sbjct: 1175 VTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPT 1234

Query: 1021 SDDFGEFQSEKPKI 1034
                    +EKP I
Sbjct: 1235 PTSASYSHTEKPGI 1248


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 20/31 (64%), Positives = 20/31 (64%)

Query: 4   RPGAGSGGGGAAGAGAGSAGGGGFMFPVAGG 34
           RPGAG GGGG  G G GS GGGG     AGG
Sbjct: 245 RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGG 275



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 33/111 (29%), Positives = 43/111 (38%), Gaps = 9/111 (8%)

Query: 12  GGAAGAGAGS---AGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVMQPNMQGIMGMNY 68
           GG   AG  S   +   G   P      P      P    G P  S   P     MG++ 
Sbjct: 763 GGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPG--MGISA 820

Query: 69  SSQM-SQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQ 118
           ++QM  QGP      +P+G MP+AGM      PF G        +P M +Q
Sbjct: 821 NNQMHGQGPSQPCGAVPLGRMPSAGMQ---NRPFPGNMSSMTPSSPGMSQQ 868



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 13/20 (65%), Positives = 13/20 (65%)

Query: 6   GAGSGGGGAAGAGAGSAGGG 25
           G   GGGG  GAGAG AG G
Sbjct: 260 GGSGGGGGGGGAGAGGAGAG 279



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 20/118 (16%)

Query: 6   GAGSGGGGA---------AGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVM 56
           GAG+GG GA         A A AG  GGGG+     GG       L   +QQG  M  +M
Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY-----GGSSAGYGVLSSPRQQGGGM--MM 322

Query: 57  QPNMQGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQ---APFLGMRPPGPQY 111
            P   G   ++ ++  S      Q        P+   P L Q   +P   MR  G  Y
Sbjct: 323 GPGGGGAASLSKAAAGSAAG-GFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 23/104 (22%), Positives = 38/104 (36%), Gaps = 7/104 (6%)

Query: 38  PQAGLMPMQQQGFPMVSVMQPNMQGIMGMNYSSQMSQGPIAMQAGIPM-----GPMPAAG 92
           P     P   Q +P + +       + GM Y  Q   G    +    +     G    +G
Sbjct: 488 PGGSYGPPGPQRYP-IGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSG 546

Query: 93  MPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEE 136
               GQ P+   +P  P   P  Q     + Q+R++ QQ + +E
Sbjct: 547 YCQQGQQPYYSQQPQPPHLPPQAQ-YLPSQSQQRYQPQQDMSQE 589



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 14/36 (38%), Positives = 15/36 (41%)

Query: 6   GAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAG 41
           G G  GGG  G GAG+ G G      A       AG
Sbjct: 258 GGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAG 293


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 20/31 (64%), Positives = 20/31 (64%)

Query: 4   RPGAGSGGGGAAGAGAGSAGGGGFMFPVAGG 34
           RPGAG GGGG  G G GS GGGG     AGG
Sbjct: 245 RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGG 275



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 33/111 (29%), Positives = 43/111 (38%), Gaps = 9/111 (8%)

Query: 12  GGAAGAGAGS---AGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVMQPNMQGIMGMNY 68
           GG   AG  S   +   G   P      P      P    G P  S   P     MG++ 
Sbjct: 750 GGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPG--MGISA 807

Query: 69  SSQM-SQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQ 118
           ++QM  QGP      +P+G MP+AGM      PF G        +P M +Q
Sbjct: 808 NNQMHGQGPSQPCGAVPLGRMPSAGMQ---NRPFPGNMSSMTPSSPGMSQQ 855



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 44/181 (24%), Positives = 62/181 (34%), Gaps = 49/181 (27%)

Query: 2   ALRPGAGSGGGGAAGAGAGSAGGGGFMFPVAG------------GIRPPQAGLMPMQQQG 49
           A   GA +GG  AA AG G     G  +  A              + P   G    + QG
Sbjct: 399 AAAAGAAAGGQQAA-AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQG 457

Query: 50  FPM--VSVMQPNMQGIMGMNYSSQMSQG----------------PIAMQAGIP------- 84
            PM  + + +P + G MG N  SQ  Q                 PI +Q   P       
Sbjct: 458 SPMDPMVMKRPQLYG-MGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQ 516

Query: 85  ---------MGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLE 135
                     G    +G    GQ P+   +P  P   P  Q     + Q+R++ QQ + +
Sbjct: 517 YPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ-YLPSQSQQRYQPQQDMSQ 575

Query: 136 E 136
           E
Sbjct: 576 E 576



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 13/20 (65%), Positives = 13/20 (65%)

Query: 6   GAGSGGGGAAGAGAGSAGGG 25
           G   GGGG  GAGAG AG G
Sbjct: 260 GGSGGGGGGGGAGAGGAGAG 279



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 20/118 (16%)

Query: 6   GAGSGGGGA---------AGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVM 56
           GAG+GG GA         A A AG  GGGG+     GG       L   +QQG  M  +M
Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY-----GGSSAGYGVLSSPRQQGGGM--MM 322

Query: 57  QPNMQGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQ---APFLGMRPPGPQY 111
            P   G   ++ ++  S      Q        P+   P L Q   +P   MR  G  Y
Sbjct: 323 GPGGGGAASLSKAAAGSAAG-GFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 14/36 (38%), Positives = 15/36 (41%)

Query: 6   GAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAG 41
           G G  GGG  G GAG+ G G      A       AG
Sbjct: 258 GGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAG 293


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 20/31 (64%), Positives = 20/31 (64%)

Query: 4   RPGAGSGGGGAAGAGAGSAGGGGFMFPVAGG 34
           RPGAG GGGG  G G GS GGGG     AGG
Sbjct: 245 RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGG 275



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 33/111 (29%), Positives = 43/111 (38%), Gaps = 9/111 (8%)

Query: 12  GGAAGAGAGS---AGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVMQPNMQGIMGMNY 68
           GG   AG  S   +   G   P      P      P    G P  S   P     MG++ 
Sbjct: 750 GGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPG--MGISA 807

Query: 69  SSQM-SQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQ 118
           ++QM  QGP      +P+G MP+AGM      PF G        +P M +Q
Sbjct: 808 NNQMHGQGPSQPCGAVPLGRMPSAGMQ---NRPFPGNMSSMTPSSPGMSQQ 855



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 44/181 (24%), Positives = 62/181 (34%), Gaps = 49/181 (27%)

Query: 2   ALRPGAGSGGGGAAGAGAGSAGGGGFMFPVAG------------GIRPPQAGLMPMQQQG 49
           A   GA +GG  AA AG G     G  +  A              + P   G    + QG
Sbjct: 399 AAAAGAAAGGQQAA-AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQG 457

Query: 50  FPM--VSVMQPNMQGIMGMNYSSQMSQG----------------PIAMQAGIP------- 84
            PM  + + +P + G MG N  SQ  Q                 PI +Q   P       
Sbjct: 458 SPMDPMVMKRPQLYG-MGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQ 516

Query: 85  ---------MGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLE 135
                     G    +G    GQ P+   +P  P   P  Q     + Q+R++ QQ + +
Sbjct: 517 YPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ-YLPSQSQQRYQPQQDMSQ 575

Query: 136 E 136
           E
Sbjct: 576 E 576



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 13/20 (65%), Positives = 13/20 (65%)

Query: 6   GAGSGGGGAAGAGAGSAGGG 25
           G   GGGG  GAGAG AG G
Sbjct: 260 GGSGGGGGGGGAGAGGAGAG 279



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 20/118 (16%)

Query: 6   GAGSGGGGA---------AGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVM 56
           GAG+GG GA         A A AG  GGGG+     GG       L   +QQG  M  +M
Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY-----GGSSAGYGVLSSPRQQGGGM--MM 322

Query: 57  QPNMQGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQ---APFLGMRPPGPQY 111
            P   G   ++ ++  S      Q        P+   P L Q   +P   MR  G  Y
Sbjct: 323 GPGGGGAASLSKAAAGSAAG-GFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 14/36 (38%), Positives = 15/36 (41%)

Query: 6   GAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAG 41
           G G  GGG  G GAG+ G G      A       AG
Sbjct: 258 GGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAG 293


>gi|45439359 triple functional domain (PTPRF interacting) [Homo
            sapiens]
          Length = 3097

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 62/275 (22%), Positives = 92/275 (33%), Gaps = 23/275 (8%)

Query: 6    GAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPMVSVMQPNMQGIMG 65
            G G GG G +G G GS GGG           P   G  P   +  P   + QP       
Sbjct: 2293 GGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPS-RIPQPVRHHPPV 2351

Query: 66   MNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQK 125
            +  S+  SQ      +G      P   +P  G AP  G  P  P   P        E++ 
Sbjct: 2352 LVSSAASSQAEADKMSGT---STPGPSLPPPGAAPEAG--PSAPSRRPPGADAEGSEREA 2406

Query: 126  RFEQQQKLLEEERK----------RRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGN 175
                + K+LE  RK              ++ +  L  L   KP+ G      A   +   
Sbjct: 2407 EPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAG------AASPLNSP 2460

Query: 176  LDGFSRDAKMHPTPASHPKKPGPSLEEKFLVSCDISTSGQEQIKLNTSEVGHKALGPGSS 235
            L          P P S P + G S       S   S  G      ++  +  +     + 
Sbjct: 2461 LSSAVPSLGKEPFPPSSPLQKGGSFWSSIPAS-PASRPGSFTFPGDSDSLQRQTPRHAAP 2519

Query: 236  KKYPSLMASNGVAVDGCVSGTTTAEAENTSDQNLS 270
             K    M++   A +  V  T +  +E++S  N+S
Sbjct: 2520 GKDTDRMSTCSSASEQSVQSTQSNGSESSSSSNIS 2554


>gi|4503593 epidermal growth factor receptor pathway substrate 15
           isoform A [Homo sapiens]
          Length = 896

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 19/94 (20%)

Query: 325 LMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRGVPAMSPDALNQFPAAP 384
           L  SGLP   LG+IW LA+    G L K+E +  L ++A  Q G+               
Sbjct: 43  LKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEV------------- 89

Query: 385 IPTLSGFSMTLPTP----VSQPTVIPSGPAGSMP 414
             +LS  ++ +P P     S P +I    A  +P
Sbjct: 90  --SLSSLNLAVPPPRFHDTSSPLLISGTSAAELP 121



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 2/60 (3%)

Query: 320 KLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMI--AVTQRGVPAMSPDAL 377
           K+ P+L++S LP + LG++W L++    G L ++E    + ++  A+ +  VP   P AL
Sbjct: 150 KVKPVLLNSKLPVDILGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPAL 209



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 2/51 (3%)

Query: 324 ILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRGVPAMSP 374
           I + +GLP   L  IW+L +    GKL+K++    LA   ++Q+ +  + P
Sbjct: 251 IFLKTGLPSTLLAHIWSLCDTKDCGKLSKDQF--ALAFHLISQKLIKGIDP 299


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 97/494 (19%), Positives = 176/494 (35%), Gaps = 62/494 (12%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYS 680
            S    +S +    + V +T    +   +TGS  T+T+   ++T++++    E ++  E S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690

Query: 681  G----------LAPVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
            G             V          +   S I++      +      E S     S  GS
Sbjct: 691  GTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGS 750

Query: 731  TVKG----GQNSTAASTKYDVFRQLSLEG------SGLGVEDLKDNTPSGKSDDDFADFH 780
                    G  +T AST        S+ G      S +G E  K +T S K    F +  
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-- 808

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
                   NS+ ++         T  ++ +V +    +I  S+ G E +    +   +   
Sbjct: 809  -------NSETTIAST------TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTT 855

Query: 841  ADVGGDLKHVMSDSSLDLPTVS--GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSD 898
            A   G      S  S +  T +  G     A  E              + +T TS + S+
Sbjct: 856  ASTEGSETTTASTESSETTTATTIGSETTTASTEG-------------SETTTTSTEGSE 902

Query: 899  RDDA-TQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKV---TTFVSED 954
               A T+G +++     + +GS + T+  +  ET+  S+E   +T++S     T  VS +
Sbjct: 903  TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 955  ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQ 1014
                TT   + S   T      +    +    + T   +  +E +  ++  S  ++ ++ 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1015 ETPNECSDDFG-EFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRS 1073
             T    +   G E  +     S+   +  T      +S E   SE  T  +S  GS   +
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTE--GSETTT--VSTTGSETTT 1075

Query: 1074 LSLGDKEISRSSPS 1087
             S  D E +  S S
Sbjct: 1076 ASTADLETTTVSTS 1089



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 71/368 (19%), Positives = 136/368 (36%), Gaps = 27/368 (7%)

Query: 636 VFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF---SLFG-EYSGLAPVGEQDDF 691
           V + S  V+T  + GS     +   ++T++++    E    S+ G E S  +  G +   
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 692 ADFMAFSNSSISSEQKPDDKYDALKEEASPVPLT-SNVGSTVKGGQNSTAASTKYDVFRQ 750
           A       ++ S+E            E + V +T S   +T   G   TA ST       
Sbjct: 376 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 751 LSLEGSGLGVEDLKDN-TPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSAS 809
            S EGS + +    D+ T +  ++       ++  S   +  + G +     +T  ++ +
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 810 VKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS--GQHPP 867
           V ++   +   S+ G E +  + +   +M      G     +S +  +  TVS  G    
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 868 AADIEDLKYAAF---------------GSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFV 912
               E  +                   G+ +++ A S  T+   +D ++ T     S   
Sbjct: 555 TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 614

Query: 913 LSAGSGSPSATSILQKKETSFGS---SENITMTSLSKVTTFVSEDALPETTFPALASFKD 969
            ++ +GS + T+     ET+  S   SE  T+++    TT VS      T      S   
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 970 TIPQTSEQ 977
           T+  T  +
Sbjct: 675 TVSATGSE 682



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 87/507 (17%), Positives = 172/507 (33%), Gaps = 53/507 (10%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGE----FSLF 676
            S    +S      + VF+      TP + GS  T  + A ++T++++    E     +  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 677  GEYSGLAPVGEQDDFAD------FMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
             E +  + +G +            ++ + S  ++    D + +    E S     S  G 
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 731  TVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSD 790
                   + +  T        +   S +G E  K +T S +    FA    +  +S    
Sbjct: 282  ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS---- 337

Query: 791  KSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHV 850
             ++G +      T  ++ +   +   +   S+ G E +  A +   +   A   G     
Sbjct: 338  -TVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE-TTTASTEGSETTTASTEGSEATT 395

Query: 851  MSDSSLDLPTVS-------GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDAT 903
            +S +  +  TVS             +++  +    F + +++   S +T    SD +  T
Sbjct: 396  VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTT 455

Query: 904  QGRKLSPFVLSAGSGSPSATSILQKKETSFGS-----------------------SENIT 940
               + S       +GS + T+     ET+  S                       SE   
Sbjct: 456  ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 941  MTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQ 1000
            +++     T VS +    TT     S   T+  T  +    + +  + T      AE + 
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575

Query: 1001 EAT--CPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            ++T    + A+S A  ET    + D     SE    S  D    ++ +    +     + 
Sbjct: 576  DSTEGSGTTAASTAGSETTTVSTAD-----SENTTASTADSETTSASTTGSETTTASTTS 630

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSS 1085
              T   S +GS   ++S  D E +  S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVS 657


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 98/494 (19%), Positives = 178/494 (36%), Gaps = 62/494 (12%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYS 680
            S    +S +    + V +T    +   +TGS  T+T+   ++T++++    E ++  E S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690

Query: 681  GLAPV---GEQDDFADFMAFSNSSISSEQK-------PDDKYDALKEEASPVPLTSNVGS 730
            G   V   G +           ++ S+E            +      E S     S  GS
Sbjct: 691  GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS 750

Query: 731  TVKG----GQNSTAASTKYDVFRQLSLEG------SGLGVEDLKDNTPSGKSDDDFADFH 780
                    G  +T AST        S+ G      S +G E  K +T S K    F +  
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-- 808

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
                   NS+ ++         T  ++ +V +    +I  S+ G E +    +   +   
Sbjct: 809  -------NSETTIAST------TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTT 855

Query: 841  ADVGGDLKHVMSDSSLDLPTVS--GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSD 898
            A   G      S  S +  T +  G     A  E              + +T TS + S+
Sbjct: 856  ASTEGSETTTASTESSETTTATTIGSETTTASTEG-------------SETTTTSTEGSE 902

Query: 899  RDDA-TQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKV---TTFVSED 954
               A T+G +++     + +GS + T+  +  ET+  S+E   +T++S     T  VS +
Sbjct: 903  TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 955  ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQ 1014
                TT   + S   T      +    +    + T   +  +E +  ++  S  ++ ++ 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1015 ETPNECSDDFG-EFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRS 1073
             T    +   G E  +     S+   +  T      +S E   SE  T  +S  GS   +
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTE--GSETTT--VSTTGSETTT 1075

Query: 1074 LSLGDKEISRSSPS 1087
             S  D E +  S S
Sbjct: 1076 ASTADLETTTVSTS 1089



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 71/368 (19%), Positives = 136/368 (36%), Gaps = 27/368 (7%)

Query: 636 VFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF---SLFG-EYSGLAPVGEQDDF 691
           V + S  V+T  + GS     +   ++T++++    E    S+ G E S  +  G +   
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 692 ADFMAFSNSSISSEQKPDDKYDALKEEASPVPLT-SNVGSTVKGGQNSTAASTKYDVFRQ 750
           A       ++ S+E            E + V +T S   +T   G   TA ST       
Sbjct: 376 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 751 LSLEGSGLGVEDLKDN-TPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSAS 809
            S EGS + +    D+ T +  ++       ++  S   +  + G +     +T  ++ +
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 810 VKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS--GQHPP 867
           V ++   +   S+ G E +  + +   +M      G     +S +  +  TVS  G    
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 868 AADIEDLKYAAF---------------GSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFV 912
               E  +                   G+ +++ A S  T+   +D ++ T     S   
Sbjct: 555 TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 614

Query: 913 LSAGSGSPSATSILQKKETSFGS---SENITMTSLSKVTTFVSEDALPETTFPALASFKD 969
            ++ +GS + T+     ET+  S   SE  T+++    TT VS      T      S   
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 970 TIPQTSEQ 977
           T+  T  +
Sbjct: 675 TVSATGSE 682



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 87/507 (17%), Positives = 172/507 (33%), Gaps = 53/507 (10%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGE----FSLF 676
            S    +S      + VF+      TP + GS  T  + A ++T++++    E     +  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 677  GEYSGLAPVGEQDDFAD------FMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
             E +  + +G +            ++ + S  ++    D + +    E S     S  G 
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 731  TVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSD 790
                   + +  T        +   S +G E  K +T S +    FA    +  +S    
Sbjct: 282  ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS---- 337

Query: 791  KSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHV 850
             ++G +      T  ++ +   +   +   S+ G E +  A +   +   A   G     
Sbjct: 338  -TVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE-TTTASTEGSETTTASTEGSEATT 395

Query: 851  MSDSSLDLPTVS-------GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDAT 903
            +S +  +  TVS             +++  +    F + +++   S +T    SD +  T
Sbjct: 396  VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTT 455

Query: 904  QGRKLSPFVLSAGSGSPSATSILQKKETSFGS-----------------------SENIT 940
               + S       +GS + T+     ET+  S                       SE   
Sbjct: 456  ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 941  MTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQ 1000
            +++     T VS +    TT     S   T+  T  +    + +  + T      AE + 
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575

Query: 1001 EAT--CPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            ++T    + A+S A  ET    + D     SE    S  D    ++ +    +     + 
Sbjct: 576  DSTEGSGTTAASTAGSETTTVSTAD-----SENTTASTADSETTSASTTGSETTTASTTS 630

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSS 1085
              T   S +GS   ++S  D E +  S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVS 657


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 98/494 (19%), Positives = 178/494 (36%), Gaps = 62/494 (12%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYS 680
            S    +S +    + V +T    +   +TGS  T+T+   ++T++++    E ++  E S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690

Query: 681  GLAPV---GEQDDFADFMAFSNSSISSEQK-------PDDKYDALKEEASPVPLTSNVGS 730
            G   V   G +           ++ S+E            +      E S     S  GS
Sbjct: 691  GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS 750

Query: 731  TVKG----GQNSTAASTKYDVFRQLSLEG------SGLGVEDLKDNTPSGKSDDDFADFH 780
                    G  +T AST        S+ G      S +G E  K +T S K    F +  
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-- 808

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
                   NS+ ++         T  ++ +V +    +I  S+ G E +    +   +   
Sbjct: 809  -------NSETTIAST------TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTT 855

Query: 841  ADVGGDLKHVMSDSSLDLPTVS--GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSD 898
            A   G      S  S +  T +  G     A  E              + +T TS + S+
Sbjct: 856  ASTEGSETTTASTESSETTTATTIGSETTTASTEG-------------SETTTTSTEGSE 902

Query: 899  RDDA-TQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKV---TTFVSED 954
               A T+G +++     + +GS + T+  +  ET+  S+E   +T++S     T  VS +
Sbjct: 903  TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 955  ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQ 1014
                TT   + S   T      +    +    + T   +  +E +  ++  S  ++ ++ 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1015 ETPNECSDDFG-EFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRS 1073
             T    +   G E  +     S+   +  T      +S E   SE  T  +S  GS   +
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTE--GSETTT--VSTTGSETTT 1075

Query: 1074 LSLGDKEISRSSPS 1087
             S  D E +  S S
Sbjct: 1076 ASTADLETTTVSTS 1089



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 71/368 (19%), Positives = 136/368 (36%), Gaps = 27/368 (7%)

Query: 636 VFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF---SLFG-EYSGLAPVGEQDDF 691
           V + S  V+T  + GS     +   ++T++++    E    S+ G E S  +  G +   
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 692 ADFMAFSNSSISSEQKPDDKYDALKEEASPVPLT-SNVGSTVKGGQNSTAASTKYDVFRQ 750
           A       ++ S+E            E + V +T S   +T   G   TA ST       
Sbjct: 376 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 751 LSLEGSGLGVEDLKDN-TPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSAS 809
            S EGS + +    D+ T +  ++       ++  S   +  + G +     +T  ++ +
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 810 VKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS--GQHPP 867
           V ++   +   S+ G E +  + +   +M      G     +S +  +  TVS  G    
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 868 AADIEDLKYAAF---------------GSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFV 912
               E  +                   G+ +++ A S  T+   +D ++ T     S   
Sbjct: 555 TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 614

Query: 913 LSAGSGSPSATSILQKKETSFGS---SENITMTSLSKVTTFVSEDALPETTFPALASFKD 969
            ++ +GS + T+     ET+  S   SE  T+++    TT VS      T      S   
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 970 TIPQTSEQ 977
           T+  T  +
Sbjct: 675 TVSATGSE 682



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 87/507 (17%), Positives = 172/507 (33%), Gaps = 53/507 (10%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGE----FSLF 676
            S    +S      + VF+      TP + GS  T  + A ++T++++    E     +  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 677  GEYSGLAPVGEQDDFAD------FMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
             E +  + +G +            ++ + S  ++    D + +    E S     S  G 
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 731  TVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSD 790
                   + +  T        +   S +G E  K +T S +    FA    +  +S    
Sbjct: 282  ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS---- 337

Query: 791  KSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHV 850
             ++G +      T  ++ +   +   +   S+ G E +  A +   +   A   G     
Sbjct: 338  -TVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE-TTTASTEGSETTTASTEGSEATT 395

Query: 851  MSDSSLDLPTVS-------GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDAT 903
            +S +  +  TVS             +++  +    F + +++   S +T    SD +  T
Sbjct: 396  VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTT 455

Query: 904  QGRKLSPFVLSAGSGSPSATSILQKKETSFGS-----------------------SENIT 940
               + S       +GS + T+     ET+  S                       SE   
Sbjct: 456  ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 941  MTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQ 1000
            +++     T VS +    TT     S   T+  T  +    + +  + T      AE + 
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575

Query: 1001 EAT--CPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            ++T    + A+S A  ET    + D     SE    S  D    ++ +    +     + 
Sbjct: 576  DSTEGSGTTAASTAGSETTTVSTAD-----SENTTASTADSETTSASTTGSETTTASTTS 630

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSS 1085
              T   S +GS   ++S  D E +  S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVS 657


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 98/494 (19%), Positives = 178/494 (36%), Gaps = 62/494 (12%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYS 680
            S    +S +    + V +T    +   +TGS  T+T+   ++T++++    E ++  E S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690

Query: 681  GLAPV---GEQDDFADFMAFSNSSISSEQK-------PDDKYDALKEEASPVPLTSNVGS 730
            G   V   G +           ++ S+E            +      E S     S  GS
Sbjct: 691  GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS 750

Query: 731  TVKG----GQNSTAASTKYDVFRQLSLEG------SGLGVEDLKDNTPSGKSDDDFADFH 780
                    G  +T AST        S+ G      S +G E  K +T S K    F +  
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-- 808

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
                   NS+ ++         T  ++ +V +    +I  S+ G E +    +   +   
Sbjct: 809  -------NSETTIAST------TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTT 855

Query: 841  ADVGGDLKHVMSDSSLDLPTVS--GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSD 898
            A   G      S  S +  T +  G     A  E              + +T TS + S+
Sbjct: 856  ASTEGSETTTASTESSETTTATTIGSETTTASTEG-------------SETTTTSTEGSE 902

Query: 899  RDDA-TQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKV---TTFVSED 954
               A T+G +++     + +GS + T+  +  ET+  S+E   +T++S     T  VS +
Sbjct: 903  TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 955  ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQ 1014
                TT   + S   T      +    +    + T   +  +E +  ++  S  ++ ++ 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1015 ETPNECSDDFG-EFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRS 1073
             T    +   G E  +     S+   +  T      +S E   SE  T  +S  GS   +
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTE--GSETTT--VSTTGSETTT 1075

Query: 1074 LSLGDKEISRSSPS 1087
             S  D E +  S S
Sbjct: 1076 ASTADLETTTVSTS 1089



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 71/368 (19%), Positives = 136/368 (36%), Gaps = 27/368 (7%)

Query: 636 VFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF---SLFG-EYSGLAPVGEQDDF 691
           V + S  V+T  + GS     +   ++T++++    E    S+ G E S  +  G +   
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 692 ADFMAFSNSSISSEQKPDDKYDALKEEASPVPLT-SNVGSTVKGGQNSTAASTKYDVFRQ 750
           A       ++ S+E            E + V +T S   +T   G   TA ST       
Sbjct: 376 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 751 LSLEGSGLGVEDLKDN-TPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSAS 809
            S EGS + +    D+ T +  ++       ++  S   +  + G +     +T  ++ +
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 810 VKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS--GQHPP 867
           V ++   +   S+ G E +  + +   +M      G     +S +  +  TVS  G    
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 868 AADIEDLKYAAF---------------GSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFV 912
               E  +                   G+ +++ A S  T+   +D ++ T     S   
Sbjct: 555 TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 614

Query: 913 LSAGSGSPSATSILQKKETSFGS---SENITMTSLSKVTTFVSEDALPETTFPALASFKD 969
            ++ +GS + T+     ET+  S   SE  T+++    TT VS      T      S   
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 970 TIPQTSEQ 977
           T+  T  +
Sbjct: 675 TVSATGSE 682



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 87/507 (17%), Positives = 172/507 (33%), Gaps = 53/507 (10%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGE----FSLF 676
            S    +S      + VF+      TP + GS  T  + A ++T++++    E     +  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 677  GEYSGLAPVGEQDDFAD------FMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
             E +  + +G +            ++ + S  ++    D + +    E S     S  G 
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 731  TVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSD 790
                   + +  T        +   S +G E  K +T S +    FA    +  +S    
Sbjct: 282  ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS---- 337

Query: 791  KSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHV 850
             ++G +      T  ++ +   +   +   S+ G E +  A +   +   A   G     
Sbjct: 338  -TVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE-TTTASTEGSETTTASTEGSEATT 395

Query: 851  MSDSSLDLPTVS-------GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDAT 903
            +S +  +  TVS             +++  +    F + +++   S +T    SD +  T
Sbjct: 396  VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTT 455

Query: 904  QGRKLSPFVLSAGSGSPSATSILQKKETSFGS-----------------------SENIT 940
               + S       +GS + T+     ET+  S                       SE   
Sbjct: 456  ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 941  MTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQ 1000
            +++     T VS +    TT     S   T+  T  +    + +  + T      AE + 
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575

Query: 1001 EAT--CPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            ++T    + A+S A  ET    + D     SE    S  D    ++ +    +     + 
Sbjct: 576  DSTEGSGTTAASTAGSETTTVSTAD-----SENTTASTADSETTSASTTGSETTTASTTS 630

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSS 1085
              T   S +GS   ++S  D E +  S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVS 657


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 98/494 (19%), Positives = 178/494 (36%), Gaps = 62/494 (12%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYS 680
            S    +S +    + V +T    +   +TGS  T+T+   ++T++++    E ++  E S
Sbjct: 652  SETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 711

Query: 681  GLAPV---GEQDDFADFMAFSNSSISSEQK-------PDDKYDALKEEASPVPLTSNVGS 730
            G   V   G +           ++ S+E            +      E S     S  GS
Sbjct: 712  GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS 771

Query: 731  TVKG----GQNSTAASTKYDVFRQLSLEG------SGLGVEDLKDNTPSGKSDDDFADFH 780
                    G  +T AST        S+ G      S +G E  K +T S K    F +  
Sbjct: 772  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-- 829

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
                   NS+ ++         T  ++ +V +    +I  S+ G E +    +   +   
Sbjct: 830  -------NSETTIAST------TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTT 876

Query: 841  ADVGGDLKHVMSDSSLDLPTVS--GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSD 898
            A   G      S  S +  T +  G     A  E              + +T TS + S+
Sbjct: 877  ASTEGSETTTASTESSETTTATTIGSETTTASTEG-------------SETTTTSTEGSE 923

Query: 899  RDDA-TQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKV---TTFVSED 954
               A T+G +++     + +GS + T+  +  ET+  S+E   +T++S     T  VS +
Sbjct: 924  TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 980

Query: 955  ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQ 1014
                TT   + S   T      +    +    + T   +  +E +  ++  S  ++ ++ 
Sbjct: 981  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1040

Query: 1015 ETPNECSDDFG-EFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRS 1073
             T    +   G E  +     S+   +  T      +S E   SE  T  +S  GS   +
Sbjct: 1041 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTE--GSETTT--VSTTGSETTT 1096

Query: 1074 LSLGDKEISRSSPS 1087
             S  D E +  S S
Sbjct: 1097 ASTADLETTTVSTS 1110



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 71/368 (19%), Positives = 136/368 (36%), Gaps = 27/368 (7%)

Query: 636 VFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF---SLFG-EYSGLAPVGEQDDF 691
           V + S  V+T  + GS     +   ++T++++    E    S+ G E S  +  G +   
Sbjct: 337 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 396

Query: 692 ADFMAFSNSSISSEQKPDDKYDALKEEASPVPLT-SNVGSTVKGGQNSTAASTKYDVFRQ 750
           A       ++ S+E            E + V +T S   +T   G   TA ST       
Sbjct: 397 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 456

Query: 751 LSLEGSGLGVEDLKDN-TPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSAS 809
            S EGS + +    D+ T +  ++       ++  S   +  + G +     +T  ++ +
Sbjct: 457 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 516

Query: 810 VKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS--GQHPP 867
           V ++   +   S+ G E +  + +   +M      G     +S +  +  TVS  G    
Sbjct: 517 VFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 575

Query: 868 AADIEDLKYAAF---------------GSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFV 912
               E  +                   G+ +++ A S  T+   +D ++ T     S   
Sbjct: 576 TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 635

Query: 913 LSAGSGSPSATSILQKKETSFGS---SENITMTSLSKVTTFVSEDALPETTFPALASFKD 969
            ++ +GS + T+     ET+  S   SE  T+++    TT VS      T      S   
Sbjct: 636 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 695

Query: 970 TIPQTSEQ 977
           T+  T  +
Sbjct: 696 TVSATGSE 703



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 87/507 (17%), Positives = 172/507 (33%), Gaps = 53/507 (10%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGE----FSLF 676
            S    +S      + VF+      TP + GS  T  + A ++T++++    E     +  
Sbjct: 183  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 242

Query: 677  GEYSGLAPVGEQDDFAD------FMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
             E +  + +G +            ++ + S  ++    D + +    E S     S  G 
Sbjct: 243  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 302

Query: 731  TVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSD 790
                   + +  T        +   S +G E  K +T S +    FA    +  +S    
Sbjct: 303  ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS---- 358

Query: 791  KSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHV 850
             ++G +      T  ++ +   +   +   S+ G E +  A +   +   A   G     
Sbjct: 359  -TVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE-TTTASTEGSETTTASTEGSEATT 416

Query: 851  MSDSSLDLPTVS-------GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDAT 903
            +S +  +  TVS             +++  +    F + +++   S +T    SD +  T
Sbjct: 417  VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTT 476

Query: 904  QGRKLSPFVLSAGSGSPSATSILQKKETSFGS-----------------------SENIT 940
               + S       +GS + T+     ET+  S                       SE   
Sbjct: 477  ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 536

Query: 941  MTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQ 1000
            +++     T VS +    TT     S   T+  T  +    + +  + T      AE + 
Sbjct: 537  VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 596

Query: 1001 EAT--CPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            ++T    + A+S A  ET    + D     SE    S  D    ++ +    +     + 
Sbjct: 597  DSTEGSGTTAASTAGSETTTVSTAD-----SENTTASTADSETTSASTTGSETTTASTTS 651

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSS 1085
              T   S +GS   ++S  D E +  S
Sbjct: 652  SETTTASTEGSETTTVSTTDSETTMVS 678


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 98/494 (19%), Positives = 178/494 (36%), Gaps = 62/494 (12%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYS 680
            S    +S +    + V +T    +   +TGS  T+T+   ++T++++    E ++  E S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690

Query: 681  GLAPV---GEQDDFADFMAFSNSSISSEQK-------PDDKYDALKEEASPVPLTSNVGS 730
            G   V   G +           ++ S+E            +      E S     S  GS
Sbjct: 691  GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS 750

Query: 731  TVKG----GQNSTAASTKYDVFRQLSLEG------SGLGVEDLKDNTPSGKSDDDFADFH 780
                    G  +T AST        S+ G      S +G E  K +T S K    F +  
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-- 808

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
                   NS+ ++         T  ++ +V +    +I  S+ G E +    +   +   
Sbjct: 809  -------NSETTIAST------TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTT 855

Query: 841  ADVGGDLKHVMSDSSLDLPTVS--GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSD 898
            A   G      S  S +  T +  G     A  E              + +T TS + S+
Sbjct: 856  ASTEGSETTTASTESSETTTATTIGSETTTASTEG-------------SETTTTSTEGSE 902

Query: 899  RDDA-TQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKV---TTFVSED 954
               A T+G +++     + +GS + T+  +  ET+  S+E   +T++S     T  VS +
Sbjct: 903  TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 955  ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQ 1014
                TT   + S   T      +    +    + T   +  +E +  ++  S  ++ ++ 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1015 ETPNECSDDFG-EFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRS 1073
             T    +   G E  +     S+   +  T      +S E   SE  T  +S  GS   +
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTE--GSETTT--VSTTGSETTT 1075

Query: 1074 LSLGDKEISRSSPS 1087
             S  D E +  S S
Sbjct: 1076 ASTADLETTTVSTS 1089



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 71/368 (19%), Positives = 136/368 (36%), Gaps = 27/368 (7%)

Query: 636 VFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF---SLFG-EYSGLAPVGEQDDF 691
           V + S  V+T  + GS     +   ++T++++    E    S+ G E S  +  G +   
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 692 ADFMAFSNSSISSEQKPDDKYDALKEEASPVPLT-SNVGSTVKGGQNSTAASTKYDVFRQ 750
           A       ++ S+E            E + V +T S   +T   G   TA ST       
Sbjct: 376 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 751 LSLEGSGLGVEDLKDN-TPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSAS 809
            S EGS + +    D+ T +  ++       ++  S   +  + G +     +T  ++ +
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 810 VKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS--GQHPP 867
           V ++   +   S+ G E +  + +   +M      G     +S +  +  TVS  G    
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 868 AADIEDLKYAAF---------------GSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFV 912
               E  +                   G+ +++ A S  T+   +D ++ T     S   
Sbjct: 555 TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 614

Query: 913 LSAGSGSPSATSILQKKETSFGS---SENITMTSLSKVTTFVSEDALPETTFPALASFKD 969
            ++ +GS + T+     ET+  S   SE  T+++    TT VS      T      S   
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 970 TIPQTSEQ 977
           T+  T  +
Sbjct: 675 TVSATGSE 682



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 87/507 (17%), Positives = 172/507 (33%), Gaps = 53/507 (10%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGE----FSLF 676
            S    +S      + VF+      TP + GS  T  + A ++T++++    E     +  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 677  GEYSGLAPVGEQDDFAD------FMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
             E +  + +G +            ++ + S  ++    D + +    E S     S  G 
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 731  TVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSD 790
                   + +  T        +   S +G E  K +T S +    FA    +  +S    
Sbjct: 282  ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS---- 337

Query: 791  KSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHV 850
             ++G +      T  ++ +   +   +   S+ G E +  A +   +   A   G     
Sbjct: 338  -TVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE-TTTASTEGSETTTASTEGSEATT 395

Query: 851  MSDSSLDLPTVS-------GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDAT 903
            +S +  +  TVS             +++  +    F + +++   S +T    SD +  T
Sbjct: 396  VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTT 455

Query: 904  QGRKLSPFVLSAGSGSPSATSILQKKETSFGS-----------------------SENIT 940
               + S       +GS + T+     ET+  S                       SE   
Sbjct: 456  ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 941  MTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQ 1000
            +++     T VS +    TT     S   T+  T  +    + +  + T      AE + 
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575

Query: 1001 EAT--CPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            ++T    + A+S A  ET    + D     SE    S  D    ++ +    +     + 
Sbjct: 576  DSTEGSGTTAASTAGSETTTVSTAD-----SENTTASTADSETTSASTTGSETTTASTTS 630

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSS 1085
              T   S +GS   ++S  D E +  S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVS 657


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 98/494 (19%), Positives = 178/494 (36%), Gaps = 62/494 (12%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYS 680
            S    +S +    + V +T    +   +TGS  T+T+   ++T++++    E ++  E S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690

Query: 681  GLAPV---GEQDDFADFMAFSNSSISSEQK-------PDDKYDALKEEASPVPLTSNVGS 730
            G   V   G +           ++ S+E            +      E S     S  GS
Sbjct: 691  GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS 750

Query: 731  TVKG----GQNSTAASTKYDVFRQLSLEG------SGLGVEDLKDNTPSGKSDDDFADFH 780
                    G  +T AST        S+ G      S +G E  K +T S K    F +  
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-- 808

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
                   NS+ ++         T  ++ +V +    +I  S+ G E +    +   +   
Sbjct: 809  -------NSETTIAST------TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTT 855

Query: 841  ADVGGDLKHVMSDSSLDLPTVS--GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSD 898
            A   G      S  S +  T +  G     A  E              + +T TS + S+
Sbjct: 856  ASTEGSETTTASTESSETTTATTIGSETTTASTEG-------------SETTTTSTEGSE 902

Query: 899  RDDA-TQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKV---TTFVSED 954
               A T+G +++     + +GS + T+  +  ET+  S+E   +T++S     T  VS +
Sbjct: 903  TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 955  ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQ 1014
                TT   + S   T      +    +    + T   +  +E +  ++  S  ++ ++ 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1015 ETPNECSDDFG-EFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRS 1073
             T    +   G E  +     S+   +  T      +S E   SE  T  +S  GS   +
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTE--GSETTT--VSTTGSETTT 1075

Query: 1074 LSLGDKEISRSSPS 1087
             S  D E +  S S
Sbjct: 1076 ASTADLETTTVSTS 1089



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 71/368 (19%), Positives = 136/368 (36%), Gaps = 27/368 (7%)

Query: 636 VFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF---SLFG-EYSGLAPVGEQDDF 691
           V + S  V+T  + GS     +   ++T++++    E    S+ G E S  +  G +   
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 692 ADFMAFSNSSISSEQKPDDKYDALKEEASPVPLT-SNVGSTVKGGQNSTAASTKYDVFRQ 750
           A       ++ S+E            E + V +T S   +T   G   TA ST       
Sbjct: 376 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 751 LSLEGSGLGVEDLKDN-TPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSAS 809
            S EGS + +    D+ T +  ++       ++  S   +  + G +     +T  ++ +
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 810 VKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS--GQHPP 867
           V ++   +   S+ G E +  + +   +M      G     +S +  +  TVS  G    
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 868 AADIEDLKYAAF---------------GSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFV 912
               E  +                   G+ +++ A S  T+   +D ++ T     S   
Sbjct: 555 TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 614

Query: 913 LSAGSGSPSATSILQKKETSFGS---SENITMTSLSKVTTFVSEDALPETTFPALASFKD 969
            ++ +GS + T+     ET+  S   SE  T+++    TT VS      T      S   
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 970 TIPQTSEQ 977
           T+  T  +
Sbjct: 675 TVSATGSE 682



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 87/507 (17%), Positives = 172/507 (33%), Gaps = 53/507 (10%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGE----FSLF 676
            S    +S      + VF+      TP + GS  T  + A ++T++++    E     +  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 677  GEYSGLAPVGEQDDFAD------FMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
             E +  + +G +            ++ + S  ++    D + +    E S     S  G 
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 731  TVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSD 790
                   + +  T        +   S +G E  K +T S +    FA    +  +S    
Sbjct: 282  ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS---- 337

Query: 791  KSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHV 850
             ++G +      T  ++ +   +   +   S+ G E +  A +   +   A   G     
Sbjct: 338  -TVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE-TTTASTEGSETTTASTEGSEATT 395

Query: 851  MSDSSLDLPTVS-------GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDAT 903
            +S +  +  TVS             +++  +    F + +++   S +T    SD +  T
Sbjct: 396  VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTT 455

Query: 904  QGRKLSPFVLSAGSGSPSATSILQKKETSFGS-----------------------SENIT 940
               + S       +GS + T+     ET+  S                       SE   
Sbjct: 456  ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 941  MTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQ 1000
            +++     T VS +    TT     S   T+  T  +    + +  + T      AE + 
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575

Query: 1001 EAT--CPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            ++T    + A+S A  ET    + D     SE    S  D    ++ +    +     + 
Sbjct: 576  DSTEGSGTTAASTAGSETTTVSTAD-----SENTTASTADSETTSASTTGSETTTASTTS 630

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSS 1085
              T   S +GS   ++S  D E +  S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVS 657


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 98/494 (19%), Positives = 178/494 (36%), Gaps = 62/494 (12%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYS 680
            S    +S +    + V +T    +   +TGS  T+T+   ++T++++    E ++  E S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690

Query: 681  GLAPV---GEQDDFADFMAFSNSSISSEQK-------PDDKYDALKEEASPVPLTSNVGS 730
            G   V   G +           ++ S+E            +      E S     S  GS
Sbjct: 691  GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS 750

Query: 731  TVKG----GQNSTAASTKYDVFRQLSLEG------SGLGVEDLKDNTPSGKSDDDFADFH 780
                    G  +T AST        S+ G      S +G E  K +T S K    F +  
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-- 808

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
                   NS+ ++         T  ++ +V +    +I  S+ G E +    +   +   
Sbjct: 809  -------NSETTIAST------TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTT 855

Query: 841  ADVGGDLKHVMSDSSLDLPTVS--GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSD 898
            A   G      S  S +  T +  G     A  E              + +T TS + S+
Sbjct: 856  ASTEGSETTTASTESSETTTATTIGSETTTASTEG-------------SETTTTSTEGSE 902

Query: 899  RDDA-TQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKV---TTFVSED 954
               A T+G +++     + +GS + T+  +  ET+  S+E   +T++S     T  VS +
Sbjct: 903  TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 955  ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQ 1014
                TT   + S   T      +    +    + T   +  +E +  ++  S  ++ ++ 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1015 ETPNECSDDFG-EFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRS 1073
             T    +   G E  +     S+   +  T      +S E   SE  T  +S  GS   +
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTE--GSETTT--VSTTGSETTT 1075

Query: 1074 LSLGDKEISRSSPS 1087
             S  D E +  S S
Sbjct: 1076 ASTADLETTTVSTS 1089



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 71/368 (19%), Positives = 136/368 (36%), Gaps = 27/368 (7%)

Query: 636 VFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF---SLFG-EYSGLAPVGEQDDF 691
           V + S  V+T  + GS     +   ++T++++    E    S+ G E S  +  G +   
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 692 ADFMAFSNSSISSEQKPDDKYDALKEEASPVPLT-SNVGSTVKGGQNSTAASTKYDVFRQ 750
           A       ++ S+E            E + V +T S   +T   G   TA ST       
Sbjct: 376 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 751 LSLEGSGLGVEDLKDN-TPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSAS 809
            S EGS + +    D+ T +  ++       ++  S   +  + G +     +T  ++ +
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 810 VKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS--GQHPP 867
           V ++   +   S+ G E +  + +   +M      G     +S +  +  TVS  G    
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 868 AADIEDLKYAAF---------------GSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFV 912
               E  +                   G+ +++ A S  T+   +D ++ T     S   
Sbjct: 555 TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 614

Query: 913 LSAGSGSPSATSILQKKETSFGS---SENITMTSLSKVTTFVSEDALPETTFPALASFKD 969
            ++ +GS + T+     ET+  S   SE  T+++    TT VS      T      S   
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 970 TIPQTSEQ 977
           T+  T  +
Sbjct: 675 TVSATGSE 682



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 87/507 (17%), Positives = 172/507 (33%), Gaps = 53/507 (10%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGE----FSLF 676
            S    +S      + VF+      TP + GS  T  + A ++T++++    E     +  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 677  GEYSGLAPVGEQDDFAD------FMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
             E +  + +G +            ++ + S  ++    D + +    E S     S  G 
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 731  TVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSD 790
                   + +  T        +   S +G E  K +T S +    FA    +  +S    
Sbjct: 282  ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS---- 337

Query: 791  KSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHV 850
             ++G +      T  ++ +   +   +   S+ G E +  A +   +   A   G     
Sbjct: 338  -TVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE-TTTASTEGSETTTASTEGSEATT 395

Query: 851  MSDSSLDLPTVS-------GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDAT 903
            +S +  +  TVS             +++  +    F + +++   S +T    SD +  T
Sbjct: 396  VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTT 455

Query: 904  QGRKLSPFVLSAGSGSPSATSILQKKETSFGS-----------------------SENIT 940
               + S       +GS + T+     ET+  S                       SE   
Sbjct: 456  ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 941  MTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQ 1000
            +++     T VS +    TT     S   T+  T  +    + +  + T      AE + 
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575

Query: 1001 EAT--CPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            ++T    + A+S A  ET    + D     SE    S  D    ++ +    +     + 
Sbjct: 576  DSTEGSGTTAASTAGSETTTVSTAD-----SENTTASTADSETTSASTTGSETTTASTTS 630

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSS 1085
              T   S +GS   ++S  D E +  S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVS 657


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 98/494 (19%), Positives = 178/494 (36%), Gaps = 62/494 (12%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYS 680
            S    +S +    + V +T    +   +TGS  T+T+   ++T++++    E ++  E S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690

Query: 681  GLAPV---GEQDDFADFMAFSNSSISSEQK-------PDDKYDALKEEASPVPLTSNVGS 730
            G   V   G +           ++ S+E            +      E S     S  GS
Sbjct: 691  GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS 750

Query: 731  TVKG----GQNSTAASTKYDVFRQLSLEG------SGLGVEDLKDNTPSGKSDDDFADFH 780
                    G  +T AST        S+ G      S +G E  K +T S K    F +  
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-- 808

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
                   NS+ ++         T  ++ +V +    +I  S+ G E +    +   +   
Sbjct: 809  -------NSETTIAST------TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTT 855

Query: 841  ADVGGDLKHVMSDSSLDLPTVS--GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSD 898
            A   G      S  S +  T +  G     A  E              + +T TS + S+
Sbjct: 856  ASTEGSETTTASTESSETTTATTIGSETTTASTEG-------------SETTTTSTEGSE 902

Query: 899  RDDA-TQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKV---TTFVSED 954
               A T+G +++     + +GS + T+  +  ET+  S+E   +T++S     T  VS +
Sbjct: 903  TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 955  ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQ 1014
                TT   + S   T      +    +    + T   +  +E +  ++  S  ++ ++ 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1015 ETPNECSDDFG-EFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRS 1073
             T    +   G E  +     S+   +  T      +S E   SE  T  +S  GS   +
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTE--GSETTT--VSTTGSETTT 1075

Query: 1074 LSLGDKEISRSSPS 1087
             S  D E +  S S
Sbjct: 1076 ASTADLETTTVSTS 1089



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 71/368 (19%), Positives = 136/368 (36%), Gaps = 27/368 (7%)

Query: 636 VFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF---SLFG-EYSGLAPVGEQDDF 691
           V + S  V+T  + GS     +   ++T++++    E    S+ G E S  +  G +   
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 692 ADFMAFSNSSISSEQKPDDKYDALKEEASPVPLT-SNVGSTVKGGQNSTAASTKYDVFRQ 750
           A       ++ S+E            E + V +T S   +T   G   TA ST       
Sbjct: 376 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 751 LSLEGSGLGVEDLKDN-TPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSAS 809
            S EGS + +    D+ T +  ++       ++  S   +  + G +     +T  ++ +
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 810 VKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS--GQHPP 867
           V ++   +   S+ G E +  + +   +M      G     +S +  +  TVS  G    
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 868 AADIEDLKYAAF---------------GSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFV 912
               E  +                   G+ +++ A S  T+   +D ++ T     S   
Sbjct: 555 TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 614

Query: 913 LSAGSGSPSATSILQKKETSFGS---SENITMTSLSKVTTFVSEDALPETTFPALASFKD 969
            ++ +GS + T+     ET+  S   SE  T+++    TT VS      T      S   
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 970 TIPQTSEQ 977
           T+  T  +
Sbjct: 675 TVSATGSE 682



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 87/507 (17%), Positives = 172/507 (33%), Gaps = 53/507 (10%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGE----FSLF 676
            S    +S      + VF+      TP + GS  T  + A ++T++++    E     +  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 677  GEYSGLAPVGEQDDFAD------FMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
             E +  + +G +            ++ + S  ++    D + +    E S     S  G 
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 731  TVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSD 790
                   + +  T        +   S +G E  K +T S +    FA    +  +S    
Sbjct: 282  ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS---- 337

Query: 791  KSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHV 850
             ++G +      T  ++ +   +   +   S+ G E +  A +   +   A   G     
Sbjct: 338  -TVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE-TTTASTEGSETTTASTEGSEATT 395

Query: 851  MSDSSLDLPTVS-------GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDAT 903
            +S +  +  TVS             +++  +    F + +++   S +T    SD +  T
Sbjct: 396  VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTT 455

Query: 904  QGRKLSPFVLSAGSGSPSATSILQKKETSFGS-----------------------SENIT 940
               + S       +GS + T+     ET+  S                       SE   
Sbjct: 456  ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 941  MTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQ 1000
            +++     T VS +    TT     S   T+  T  +    + +  + T      AE + 
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575

Query: 1001 EAT--CPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            ++T    + A+S A  ET    + D     SE    S  D    ++ +    +     + 
Sbjct: 576  DSTEGSGTTAASTAGSETTTVSTAD-----SENTTASTADSETTSASTTGSETTTASTTS 630

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSS 1085
              T   S +GS   ++S  D E +  S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVS 657


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 98/494 (19%), Positives = 178/494 (36%), Gaps = 62/494 (12%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEFSLFGEYS 680
            S    +S +    + V +T    +   +TGS  T+T+   ++T++++    E ++  E S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690

Query: 681  GLAPV---GEQDDFADFMAFSNSSISSEQK-------PDDKYDALKEEASPVPLTSNVGS 730
            G   V   G +           ++ S+E            +      E S     S  GS
Sbjct: 691  GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS 750

Query: 731  TVKG----GQNSTAASTKYDVFRQLSLEG------SGLGVEDLKDNTPSGKSDDDFADFH 780
                    G  +T AST        S+ G      S +G E  K +T S K    F +  
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-- 808

Query: 781  SSKFSSINSDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKL 840
                   NS+ ++         T  ++ +V +    +I  S+ G E +    +   +   
Sbjct: 809  -------NSETTIAST------TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTT 855

Query: 841  ADVGGDLKHVMSDSSLDLPTVS--GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSD 898
            A   G      S  S +  T +  G     A  E              + +T TS + S+
Sbjct: 856  ASTEGSETTTASTESSETTTATTIGSETTTASTEG-------------SETTTTSTEGSE 902

Query: 899  RDDA-TQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKV---TTFVSED 954
               A T+G +++     + +GS + T+  +  ET+  S+E   +T++S     T  VS +
Sbjct: 903  TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 955  ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQ 1014
                TT   + S   T      +    +    + T   +  +E +  ++  S  ++ ++ 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1015 ETPNECSDDFG-EFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRS 1073
             T    +   G E  +     S+   +  T      +S E   SE  T  +S  GS   +
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTE--GSETTT--VSTTGSETTT 1075

Query: 1074 LSLGDKEISRSSPS 1087
             S  D E +  S S
Sbjct: 1076 ASTADLETTTVSTS 1089



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 71/368 (19%), Positives = 136/368 (36%), Gaps = 27/368 (7%)

Query: 636 VFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGEF---SLFG-EYSGLAPVGEQDDF 691
           V + S  V+T  + GS     +   ++T++++    E    S+ G E S  +  G +   
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 692 ADFMAFSNSSISSEQKPDDKYDALKEEASPVPLT-SNVGSTVKGGQNSTAASTKYDVFRQ 750
           A       ++ S+E            E + V +T S   +T   G   TA ST       
Sbjct: 376 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 751 LSLEGSGLGVEDLKDN-TPSGKSDDDFADFHSSKFSSINSDKSLGEKAVAFRHTKEDSAS 809
            S EGS + +    D+ T +  ++       ++  S   +  + G +     +T  ++ +
Sbjct: 436 ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 810 VKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVS--GQHPP 867
           V ++   +   S+ G E +  + +   +M      G     +S +  +  TVS  G    
Sbjct: 496 VFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 868 AADIEDLKYAAF---------------GSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFV 912
               E  +                   G+ +++ A S  T+   +D ++ T     S   
Sbjct: 555 TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 614

Query: 913 LSAGSGSPSATSILQKKETSFGS---SENITMTSLSKVTTFVSEDALPETTFPALASFKD 969
            ++ +GS + T+     ET+  S   SE  T+++    TT VS      T      S   
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 970 TIPQTSEQ 977
           T+  T  +
Sbjct: 675 TVSATGSE 682



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 87/507 (17%), Positives = 172/507 (33%), Gaps = 53/507 (10%)

Query: 621  SSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSAATMTALAATKTSSLADDFGE----FSLF 676
            S    +S      + VF+      TP + GS  T  + A ++T++++    E     +  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 677  GEYSGLAPVGEQDDFAD------FMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGS 730
             E +  + +G +            ++ + S  ++    D + +    E S     S  G 
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 731  TVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSSINSD 790
                   + +  T        +   S +G E  K +T S +    FA    +  +S    
Sbjct: 282  ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS---- 337

Query: 791  KSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHV 850
             ++G +      T  ++ +   +   +   S+ G E +  A +   +   A   G     
Sbjct: 338  -TVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE-TTTASTEGSETTTASTEGSEATT 395

Query: 851  MSDSSLDLPTVS-------GQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDAT 903
            +S +  +  TVS             +++  +    F + +++   S +T    SD +  T
Sbjct: 396  VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTT 455

Query: 904  QGRKLSPFVLSAGSGSPSATSILQKKETSFGS-----------------------SENIT 940
               + S       +GS + T+     ET+  S                       SE   
Sbjct: 456  ASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515

Query: 941  MTSLSKVTTFVSEDALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQ 1000
            +++     T VS +    TT     S   T+  T  +    + +  + T      AE + 
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575

Query: 1001 EAT--CPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSE 1058
            ++T    + A+S A  ET    + D     SE    S  D    ++ +    +     + 
Sbjct: 576  DSTEGSGTTAASTAGSETTTVSTAD-----SENTTASTADSETTSASTTGSETTTASTTS 630

Query: 1059 LATFDLSVQGSHKRSLSLGDKEISRSS 1085
              T   S +GS   ++S  D E +  S
Sbjct: 631  SETTTASTEGSETTTVSTTDSETTMVS 657


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 44/178 (24%), Positives = 72/178 (40%), Gaps = 33/178 (18%)

Query: 326 MSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRG--VPAMSPDALNQFPAA 383
           + SGLP   L +IWAL++    GK+ ++E    + +I +  +G  +P + P  + Q    
Sbjct: 50  LQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQ---- 105

Query: 384 PIPTLSGFSMTLPTPVSQPTVIPSGPAGSMP-LSLGQPVMGINLVGPVGGAAAQASSGFI 442
                         P+  P +      GSMP LS+ QP   +    P+   ++  S   +
Sbjct: 106 -------------PPMFSPLISARFGMGSMPNLSIPQP---LPPAAPITSLSSATSGTNL 149

Query: 443 PTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQELPASSKTSNSQHGNSAPSLLM 500
           P       + P           S S   + + S  Q LP    +S   HG+S  SL+M
Sbjct: 150 PPLMMPTPLVP---------SVSTSSLPNGTASLIQPLPIPYSSSTLPHGSSY-SLMM 197


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 44/178 (24%), Positives = 72/178 (40%), Gaps = 33/178 (18%)

Query: 326 MSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRG--VPAMSPDALNQFPAA 383
           + SGLP   L +IWAL++    GK+ ++E    + +I +  +G  +P + P  + Q    
Sbjct: 50  LQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQ---- 105

Query: 384 PIPTLSGFSMTLPTPVSQPTVIPSGPAGSMP-LSLGQPVMGINLVGPVGGAAAQASSGFI 442
                         P+  P +      GSMP LS+ QP   +    P+   ++  S   +
Sbjct: 106 -------------PPMFSPLISARFGMGSMPNLSIPQP---LPPAAPITSLSSATSGTNL 149

Query: 443 PTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQELPASSKTSNSQHGNSAPSLLM 500
           P       + P           S S   + + S  Q LP    +S   HG+S  SL+M
Sbjct: 150 PPLMMPTPLVP---------SVSTSSLPNGTASLIQPLPIPYSSSTLPHGSSY-SLMM 197


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,907,735
Number of Sequences: 37866
Number of extensions: 2762974
Number of successful extensions: 23763
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 191
Number of HSP's successfully gapped in prelim test: 396
Number of HSP's that attempted gapping in prelim test: 16768
Number of HSP's gapped (non-prelim): 5426
length of query: 1302
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1188
effective length of database: 13,930,794
effective search space: 16549783272
effective search space used: 16549783272
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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